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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">ATCC 44560</strain>
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    </dbReference>
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    </evidence>
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        <source>
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            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
    <sequence length="316" mass="34604" checksum="C362BF1FA36FDB6C" modified="2014-04-16" version="1">MAKKCVHKGCGKTYEDENEECAYHPGPPVFHEGQKGWKCCKPRVLTFDEFLAIEPCTKGKHSDVDDTPAPEPVETPDIPNGTAVNLGSLDESLPPPAPRVPTAQAAPKPTASPAPPPESEDDDPSIAVKEGMTCRRKGCGAVHKGGDRQGEGCVHHPGAPIFHEGSKGWSCCKRRVLEFDQFMNIEGCKTKDRHLFVGSGKKNEGEEKLDTVRHDYYQTATSVVASLYLKKIDKATARVEFQASSVKLDLPTSDSKRYQTEFPLFSTIKPEESKFRILGTKLEMTLVKADGASWPVLRSDEKPTGEMIQVGRAGRA</sequence>
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<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YL16</accession>
    <name>W6YL16_COCMI</name>
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            <fullName evidence="11">Nucleoporin Nup82</fullName>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
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    <dbReference type="eggNOG" id="ENOG502QUNM">
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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    <dbReference type="PANTHER" id="PTHR13257:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP88"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR13257">
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    </dbReference>
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    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
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    <keyword evidence="2" id="KW-0813">Transport</keyword>
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            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC39897.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
    <sequence length="843" mass="93687" checksum="1ED06D0F0C6E6634" modified="2014-04-16" version="1"> </sequence>
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    <accession>W6YM96</accession>
    <name>W6YM96_COCMI</name>
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            <fullName evidence="3">UbiA prenyltransferase family protein</fullName>
        </recommendedName>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964170">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="11997" checksum="FCA31E98D1090495" modified="2014-04-16" version="1" fragment="single">MSLPKQLALLVSVSRPLSWVVAPAIWFSGLIHSGKYELVAFGVNDVYDYTSDSQNRRKTSQWTDGTALDQHHHRYVLLAAKISTALVLLITFSSWRKSSELFSCIVA</sequence>
</entry>
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    <accession>W6YP96</accession>
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            <fullName evidence="6">EXS domain-containing protein</fullName>
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    </protein>
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    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964116">
        <property type="protein sequence ID" value="EUC41177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692316.1">
        <property type="nucleotide sequence ID" value="XM_007694126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YP96"/>
    <dbReference type="STRING" id="930090.W6YP96"/>
    <dbReference type="GeneID" id="19118938"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106872"/>
    <dbReference type="eggNOG" id="KOG1162">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024081_2_1_1"/>
    <dbReference type="OrthoDB" id="2159384at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF46">
        <property type="entry name" value="PROTEIN ERD1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="6">
        <location>
            <begin position="190"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="415" mass="46932" checksum="2324A03870200AE4" modified="2014-04-16" version="1">MDGDPAIEPEIDGFTRILPLPYRVALIIVLGIWAWGLNLHYLSLIKIDVPSLIRYPSRASPHHPSHHLSCYRIATFLSIPLALSLLLFWALTHGSTKAIADWEILPNLYLLVLVIGFVAPVPFVSRNGRSRTLATLKRISTGGIAEAQDGKFGDILLADALTSYAKVLGDLFISLCMFFSSGQRSTAAPNRNCGGTFWVPFIIVVPYLIRFRQCITEYYRVKRGNERTGQINPATGWGGTHLANAAKYSTAFPVIILSALQRSPDPSSFGVSEATLYRMWLFAVIVNSGYSYYWDVAKDWDLTLFSSARIRNSPEYPWGLRRHRWFHAKEFYYAAVVVDALLRCTWSLKLSVHLDHFNDLEGGIFTMEVLEVIRRWIWIFFRVETEWVRNHKGPAPDDVLLGDVGAGNRYDDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPL9</accession>
    <name>W6YPL9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_111089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964310">
        <property type="protein sequence ID" value="EUC39605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693877.1">
        <property type="nucleotide sequence ID" value="XM_007695687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPL9"/>
    <dbReference type="GeneID" id="19119713"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111089"/>
    <dbReference type="HOGENOM" id="CLU_2209554_0_0_1"/>
    <dbReference type="OrthoDB" id="3693192at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="107" mass="12244" checksum="0200B55E885321C2" modified="2014-04-16" version="1">MTAPTMLWRVIYDGFRAQYLDGDGIWAEDQDSGITLNSGKGTLRRVLGYDFIWWLKRASPFISAYSNKRLASSKQAEQLVKEGKKNVTICEIDVYASNRRAEHYSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPU9</accession>
    <name>W6YPU9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">6-phosphogluconate dehydrogenase NADP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_106258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964104">
        <property type="protein sequence ID" value="EUC41402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692071.1">
        <property type="nucleotide sequence ID" value="XM_007693881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPU9"/>
    <dbReference type="STRING" id="930090.W6YPU9"/>
    <dbReference type="GeneID" id="19118827"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106258"/>
    <dbReference type="eggNOG" id="KOG0409">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035117_5_0_1"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF8">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE NADP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="2">
        <location>
            <begin position="9"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="363" mass="38592" checksum="8AB928C3CC8191B1" modified="2014-04-16" version="1">MDFSEKLHVGWIGLGSMGLAMAANIQKHIQQHPDAYPPLKYWNRTLSRGKPLEELGATACPTIADLVQTCNVIFISVSDDTALTTLATTIQSSGPLSQKIIIDTTTVHPSTTTTISTSFAQKNASYISAPVFGATPVATAGQLLIAVAGPPDAISRVAPLLKGVLARRVLHVGDEASQAMLLKTTSNFVTAGLMTLLSEAHILAETSGLPSSTLESLIEENFGAYALGVSQRLTSGSYLPTVGQAPASGLELGIKDVGHGVAVARKKGVQLRIGEMYLEAAGEARGYVEERGRRADSSAVYGVLRQRAGLGFESEVVRRRDGEGKKEHVVYPNIIDAYAKPQPLIYISATHLRQPFAPPLLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQJ7</accession>
    <name>W6YQJ7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_105476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964090">
        <property type="protein sequence ID" value="EUC41692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691787.1">
        <property type="nucleotide sequence ID" value="XM_007693597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQJ7"/>
    <dbReference type="GeneID" id="19118688"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105476"/>
    <dbReference type="HOGENOM" id="CLU_3049989_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="54" mass="5940" checksum="D8FF71D5ACB8F22C" modified="2014-04-16" version="1">MLGSERVGVTTKIAEVQQCPLSFPINVSTYLSDISLSQLRIHRAKSSQTPTRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQP4</accession>
    <name>W6YQP4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_40110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964088">
        <property type="protein sequence ID" value="EUC41737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691732.1">
        <property type="nucleotide sequence ID" value="XM_007693542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQP4"/>
    <dbReference type="STRING" id="930090.W6YQP4"/>
    <dbReference type="GeneID" id="19123814"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40110"/>
    <dbReference type="eggNOG" id="KOG3854">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012966_3_2_1"/>
    <dbReference type="OrthoDB" id="20772at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035240">
        <property type="entry name" value="SprT_Zn_ribbon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099:SF0">
        <property type="entry name" value="GERM CELL NUCLEAR ACIDIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17283">
        <property type="entry name" value="Zn_ribbon_SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SprT-like" evidence="2">
        <location>
            <begin position="500"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="682"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="767" mass="85530" checksum="78F900909CAD640E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR94</accession>
    <name>W6YR94_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964207">
        <property type="protein sequence ID" value="EUC40023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693455.1">
        <property type="nucleotide sequence ID" value="XM_007695265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR94"/>
    <dbReference type="STRING" id="930090.W6YR94"/>
    <dbReference type="GeneID" id="19121779"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30959"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_6_21_1"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="63"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="484" mass="54349" checksum="31A9675BC30F42BC" modified="2014-04-16" version="1">MKLAIERTGGPDADECLRDLRVTDPREDRARIEGDKDRLLRDCYAWILDDDSFQRWRTQDESRLLWIKGDPGKGKTTMVMGVIAELSRGYKTRLSSRTMVKVLTKLKLGSQSCLVTYFFCQSTRPELNNAVSVLQGLLYLLIAQKKELIRHVQKRYKAVGRLLFEGPTAVYALREVLADVLSATALPPTCLLVDALDECTSGLSELLHIITDASLGRRSRVKWLVTSRNIPEIERYLQSDAAGVKVSLEVKASHVSRAVAAFVDYKVQRLATVQQYDVSLVCKELEGVPLYRAREVLQALPPGLDPLYERMMAQIAEQDAKTVEYCRAILRSITLAFRPLQLRELHIAAGLPRDQFSNVQAVADLVGRCGSFLTMREGVVSSIHLSARDFFTIGSGRQVFSGPLEEEQKRMTYRLLDAMDSTLRRDMCSLQKPGMRIQEATGHIQGSCVPQIAYACEYWMEHLQAGGHACSSMLADGGIVHRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRG7</accession>
    <name>W6YRG7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 128 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_109639</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964198">
        <property type="protein sequence ID" value="EUC40098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693376.1">
        <property type="nucleotide sequence ID" value="XM_007695186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRG7"/>
    <dbReference type="GeneID" id="19119474"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109639"/>
    <dbReference type="eggNOG" id="ENOG502SHCN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040908_3_2_1"/>
    <dbReference type="OrthoDB" id="5959761at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071966">
        <property type="term" value="P:fungal-type cell wall polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886009" evidence="2">
        <location>
            <begin position="31"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="3">
        <location>
            <begin position="37"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="336" mass="36820" checksum="C45DAC657E62D48F" modified="2014-04-16" version="1">MPRLHTSRQHKQQMGLTTTVLSILATTALAQQSKRGFAFIGDTHKSDNRLLTSETSQLSWYYNWSPYPNSDLIPADRLEFVPMIHGIDATKDQQTERVIRGLPESSKHLLSFNEPDGSEGSGGSSISPEDAAKAYIDYVVPFRNGDSGGRKWLISHPSTTGSPNGLDWLRRFNESCYDIDSKNGCPADFVAVHWYGAFDGLAGWLGTLDEFYNTNTSRSVPLKLWITEMALPQQDADNTVDMMNQTLPYLDGEENVERYAWFGAFRPDDANEWTGDGVALFDDDGGLTELGALYMGDGFKEGQKGEGAAEDAGSGLRVSVGTMAALAVCATVFGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT53</accession>
    <name>W6YT53_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4385 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_30408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964145">
        <property type="protein sequence ID" value="EUC40703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692786.1">
        <property type="nucleotide sequence ID" value="XM_007694596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT53"/>
    <dbReference type="GeneID" id="19121669"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30408"/>
    <dbReference type="eggNOG" id="ENOG502S5KA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079668_2_0_1"/>
    <dbReference type="OrthoDB" id="2589819at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025494">
        <property type="entry name" value="DUF4385"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14328">
        <property type="entry name" value="DUF4385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="18739" checksum="08A566A3111157A6" modified="2014-04-16" version="1">MPTERLTKAQRMTYRIGRGETGVLTFEPYKSSILPLWRFKTPSIARQSSCAIYTKFLHYNDENDFIGMDMARKFLQMGMTRAKRYANHAGGRKYDKKTGQELEKSTGHTGMKEKLEASEVFREVWERAKAHEGYQMKKEAFLKEQKEWDREKKRKVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV20</accession>
    <name>W6YV20_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leo1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_8867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964104">
        <property type="protein sequence ID" value="EUC41403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692060.1">
        <property type="nucleotide sequence ID" value="XM_007693870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV20"/>
    <dbReference type="STRING" id="930090.W6YV20"/>
    <dbReference type="GeneID" id="19127325"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8867"/>
    <dbReference type="eggNOG" id="KOG2428">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030892_0_0_1"/>
    <dbReference type="OrthoDB" id="20844at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990269">
        <property type="term" value="F:RNA polymerase II C-terminal domain phosphoserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007149">
        <property type="entry name" value="Leo1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23146">
        <property type="entry name" value="LEO1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23146:SF0">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN LEO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04004">
        <property type="entry name" value="Leo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="51792" checksum="F25C6D2EE2BDA4CD" modified="2014-04-16" version="1">MSDAGHDPTLSDDEANGHATPADDGEGGTPLNTVEENGLDDDDDDLFGDGGADDDAEGDAQAEQRKLDDAELDSGDDEGRTDRVRQAEAVEEVEQQTFAYMDADLARHAVPEPTDNELYLLKIPRFLSFEDKAFDHRTFQPPTTDHHSKVGASEHFSAYHTAMTTIRWRHSPSNNAVLQSNARILRWSDGSFTLQLASDPTVQFDIDANTLAPPQINPKIPTPTAVREDKTGAKTNAKKESYTYLVAPYEEANVMRVTNKLTASLNVVPAANTKDAALEKLQNDLAKVASKGRDDADQAISFINVDEDPELRRQREEATFKEKQRQLRAREKHEARQAERANRTMGRSSGRASGGGLDVDGLEDRAPRKQQQRKGGGLRRDWSDDEDYGGPRRNREDDYDEEDDFIAASDEEPEIVEDDDDPDEGIAPSPKRARGGAVAADDDDDDDEVVVSRTKRRRVVDDDEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVC6</accession>
    <name>W6YVC6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964100">
        <property type="protein sequence ID" value="EUC41498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691987.1">
        <property type="nucleotide sequence ID" value="XM_007693797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVC6"/>
    <dbReference type="GeneID" id="19123863"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40353"/>
    <dbReference type="HOGENOM" id="CLU_1970148_0_0_1"/>
    <dbReference type="OrthoDB" id="3694462at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889267" description="Hydrophobin" evidence="1">
        <location>
            <begin position="19"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="13260" checksum="97E0ECF03961A992" modified="2014-04-16" version="1">MFVSTIVLALAGAASILAAPVAEAAPASAVQARDIPPLGSCPSWKGIYGRAGSTVCCVYSGGPTSCCVNNSPVSVYFPEVNYTYLSCQSPWFVDINNFVHFSSCYIPSNLGSANCADVPKIYGNYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVG5</accession>
    <name>W6YVG5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit J</fullName>
            <shortName evidence="5">eIF3j</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 30 kDa subunit homolog</fullName>
            <shortName evidence="5">eIF-3 30 kDa subunit homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HCR1</name>
        <name evidence="7" type="ORF">COCMIDRAFT_105929</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit J family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964098">
        <property type="protein sequence ID" value="EUC41540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691955.1">
        <property type="nucleotide sequence ID" value="XM_007693765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVG5"/>
    <dbReference type="STRING" id="930090.W6YVG5"/>
    <dbReference type="GeneID" id="19118771"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105929"/>
    <dbReference type="eggNOG" id="KOG4813">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087988_0_0_1"/>
    <dbReference type="OrthoDB" id="20381at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.60:FF:000003">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.60">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03009">
        <property type="entry name" value="eIF3j"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023194">
        <property type="entry name" value="eIF3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013906">
        <property type="entry name" value="eIF3j"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08597">
        <property type="entry name" value="eIF3_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="268" mass="29891" checksum="4EDBECE4E3D2581C" modified="2014-04-16" version="1">MAPGKWDDEEESSSPPSPTVAPIARRSKFEDEEEEDVLESWDAAEDSEVEREKAKKAAEAKAKADAEAKANHKSKAQRIEEHRQAALRRRQMEDEGESEEEETEAERRARLRQQEIDGSRAQAEELFGDLTVSNKRSGKAVTIADESDPNNTINLSSLSIFNPNTKDQFTKLRETLTPLIAANSKKGQYTLFLQEFTKQIAKDLPSEQIKKIASGLTTLSNEKMKEEKAAEKGGKKTKAAKTKTTLNASRDVGLKADTRAYDDDDFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWM7</accession>
    <name>W6YWM7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF396-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_104779</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SVP26 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964079">
        <property type="protein sequence ID" value="EUC41960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691540.1">
        <property type="nucleotide sequence ID" value="XM_007693350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWM7"/>
    <dbReference type="STRING" id="930090.W6YWM7"/>
    <dbReference type="GeneID" id="19118568"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104779"/>
    <dbReference type="eggNOG" id="KOG4136">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058268_0_0_1"/>
    <dbReference type="OrthoDB" id="28257at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097020">
        <property type="term" value="F:COPII receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007277">
        <property type="entry name" value="Svp26/Tex261"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13144:SF0">
        <property type="entry name" value="PROTEIN TEX261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13144">
        <property type="entry name" value="TEX261 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04148">
        <property type="entry name" value="Erv26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="26894" checksum="D1B347A20607D1E0" modified="2014-04-16" version="1">MWILPLLGYVGLILGFAFLTLAIASGLYYLSELVEEHTVLAKKLLYRLIYGVVGVQFLLLVVDKFPVGLSLLSVVSHGIYAQNLRRFPVVKLTDPLFLLSCALVIANHYLWFRHFSAPPANSYSSYPYTRDTNIPTFTEIAAYFGLCVWLVPFALFVSLSAGENVLPSMGSEYATGDGSSYINPGKAPDSYGSGSGVGVSGIQGKRRARSGTNAGMAKAVVTGVREWVGETGEVMGFWKGERTRPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWR1</accession>
    <name>W6YWR1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_99836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689651.1">
        <property type="nucleotide sequence ID" value="XM_007691461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWR1"/>
    <dbReference type="GeneID" id="19129546"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99836"/>
    <dbReference type="eggNOG" id="ENOG502RK4M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_589260_0_0_1"/>
    <dbReference type="OrthoDB" id="3937309at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="465" mass="51238" checksum="34AB29C78D064FE8" modified="2014-04-16" version="1" fragment="single">PLSSVASPSDPSDDVFRTPAVSGDLTRRHRNSYRLTSNDFSTLGPRNLSSIVGSVKQSDHTSVRPRERGSDATSASTSYSWYGSLSSDTRFPSSEHSQDESSPPLQLDGVRTRSHGPSPLPSMPYTRMHNDATSAPPPTLDDSRQISGGYVEAATAAVHDLQSPLDPYAEHYQRRVHTQHALLNYPTYANPANPSLSTRGNSPTFLRPSQSFRMEQGSSENAPVSVPVNHGDASRYGRVPAHRAAYQRLQSPPYTTYSGAIGGSEMSSSRYSAQPAAAPHDTSNRFRNYMAHGSATTGMPRGGEVSRSASALPMHALQHEFQMQSHHHVVEAESPRSSPRQPWGQYRAEFASHAPVRMYRSRSSFLSLQPRRDGPLSALASFEQGSGTTSRYTQSSLIRATAAATGRTYRRIRPEQRDQENHGDGMAMGREEANVAARYGDEEQYRTMMNETPPRIGRVERRMME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWW3</accession>
    <name>W6YWW3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_6741</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964017">
        <property type="protein sequence ID" value="EUC43877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689591.1">
        <property type="nucleotide sequence ID" value="XM_007691401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWW3"/>
    <dbReference type="STRING" id="930090.W6YWW3"/>
    <dbReference type="GeneID" id="19125064"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6741"/>
    <dbReference type="eggNOG" id="KOG2282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_11_6_1"/>
    <dbReference type="OrthoDB" id="10249365at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02773">
        <property type="entry name" value="MopB_Res-Cmplx1_Nad11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.740:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.210:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.740:FF:000033">
        <property type="entry name" value="NUAM protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054351">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NDUFS1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF13">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13510">
        <property type="entry name" value="Fer2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22151">
        <property type="entry name" value="Fer4_NDSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22117">
        <property type="entry name" value="Fer4_Nqo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="12">
        <location>
            <begin position="33"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="14">
        <location>
            <begin position="111"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="13">
        <location>
            <begin position="250"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC43877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="747" mass="82054" checksum="6399698E097350FE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX08</accession>
    <name>W6YX08_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964203">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="4844402at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889480" evidence="1">
        <location>
            <begin position="25"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="74" mass="7387" checksum="301E87F53B4AB5E2" modified="2014-04-16" version="1">MQFRSIILAATGLLSVAYAAPASGSPVPENPLLTRQCAANGVCAPNPTACSNLRCCSGAKQGRGGGVCCCVSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX35</accession>
    <name>W6YX35_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_109691</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964200">
        <property type="protein sequence ID" value="EUC40084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693401.1">
        <property type="nucleotide sequence ID" value="XM_007695211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX35"/>
    <dbReference type="STRING" id="930090.W6YX35"/>
    <dbReference type="GeneID" id="19119484"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109691"/>
    <dbReference type="eggNOG" id="KOG0534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_6_0_1"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF189">
        <property type="entry name" value="CYTOCHROME C MITOCHONDRIAL IMPORT FACTOR CYC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0274">FAD</keyword>
    <keyword evidence="4 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="40"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC40084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="342" mass="37588" checksum="F862CFC7EFE0C897" modified="2014-04-16" version="1">MSWLKRRAGPLIVLGSSALGGAAYRLARPADASDATLNPHTFTQYTLVSKEPVSSTSAIFTLRNSNGVSDAESIKEVSKRSVWSVQIKQPQLQIARAYTPLPRTTDSTKTGDDDLGGMRLLIRQETGGEVSTYLHRLPEQSTIELRGPNTELKLPRDIIEVIFLAGGTGIAPAMQVAQALGRRTGSKMHILWANRKREECVGGVSDDSGQDQYGQDRIGWWKSLFGSPVQAPLVEPPSATEKGAIVTELDTLKKRSEAATKGLTVNYYVDEEKTFIQPGEIEQKIRRRREEAGSRLIIVSGPDGFIEYWAGRKLWANGTEVQGPLGGQLSRMDLGEWRVVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXI2</accession>
    <name>W6YXI2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cysteine-rich transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_39686</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endomembrane system</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CYSTM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964068">
        <property type="protein sequence ID" value="EUC42250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691237.1">
        <property type="nucleotide sequence ID" value="XM_007693047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXI2"/>
    <dbReference type="GeneID" id="19123734"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39686"/>
    <dbReference type="eggNOG" id="ENOG502SBQW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156676_0_1_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051671">
        <property type="entry name" value="CYSTM1_HM_Tolerance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028144">
        <property type="entry name" value="CYSTM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35470">
        <property type="entry name" value="CADMIUM TOLERANT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35470:SF6">
        <property type="entry name" value="PROTEIN CYSTEINE-RICH TRANSMEMBRANE MODULE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12734">
        <property type="entry name" value="CYSTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cysteine-rich transmembrane" evidence="8">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="76" mass="8442" checksum="76F43A4877A41416" modified="2014-04-16" version="1">MSYPQQQQMNYGPPQPGYGPPPQQPMYYQQAPPPPPPEEKKDRGCLTACLATLCCCWLCGETCECCLDCLDCCDCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXT4</accession>
    <name>W6YXT4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964063">
        <property type="protein sequence ID" value="EUC42380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691108.1">
        <property type="nucleotide sequence ID" value="XM_007692918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXT4"/>
    <dbReference type="GeneID" id="19118353"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103665"/>
    <dbReference type="HOGENOM" id="CLU_2628453_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="78" mass="8618" checksum="E55CEBDDCD0E85B8" modified="2014-04-16" version="1" fragment="single">QCRRRVSLEIEEKAEIVEEKEEAEQAGCQGERRRAREPACSRTTDGLLLQAIFLCSCRRAGNGSRKGPCLHKAGVTCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXV2</accession>
    <name>W6YXV2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_8037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964063">
        <property type="protein sequence ID" value="EUC42393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691092.1">
        <property type="nucleotide sequence ID" value="XM_007692902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXV2"/>
    <dbReference type="GeneID" id="19125657"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8037"/>
    <dbReference type="eggNOG" id="ENOG502T9TA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1875073_0_0_1"/>
    <dbReference type="OrthoDB" id="3797248at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="136" mass="14356" checksum="71703558AA5E1850" modified="2014-04-16" version="1">MASTRPTYHIPFPTSFLAVNTPVKKTVAAVPAAEPLVPAHGFLSNRQNSGRHQSVSSISSNSSIGAPPSEASTLSPPSSPTATKHDDSPILGLKIFSPLAVNAKYAAPPGSLKEMSAAERQRRMSFERSAFLSNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXX1</accession>
    <name>W6YXX1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_6433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964009">
        <property type="protein sequence ID" value="EUC44187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689260.1">
        <property type="nucleotide sequence ID" value="XM_007691070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXX1"/>
    <dbReference type="GeneID" id="19124960"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6433"/>
    <dbReference type="HOGENOM" id="CLU_2885444_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="63" mass="6592" checksum="66C6634AFC0C6A0D" modified="2014-04-16" version="1">MPTYVLTYCNTLSIVLGIPVRNKHPGCNGNNPQGEAAGSKVEGPRGSSLQVRGLGFCVTKISC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY93</accession>
    <name>W6YY93_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_103246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964058">
        <property type="protein sequence ID" value="EUC42540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690964.1">
        <property type="nucleotide sequence ID" value="XM_007692774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY93"/>
    <dbReference type="GeneID" id="19118253"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103246"/>
    <dbReference type="eggNOG" id="ENOG502SXED">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_567587_0_0_1"/>
    <dbReference type="OrthoDB" id="4755622at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="475" mass="51724" checksum="955B96B44BDF704D" modified="2014-04-16" version="1">MDPSAIPCPSHSSGTQGLTLTPENTYIHCGPSRTNTPPHINNSNYSHSPLTPYTPHTPASTAPNTCTVDEPLYTRVAVHTAKCTECDKRNMDTMRRCPGCTFQVCQPCYEKRQRQGKGLVHGNMPSPEETGAATPGGTGARASRKKPVGSAAKAKSSEKEVDEDDSEECANGAIKGGKHTPSVPKSKAGKRSRGRSCVKDSEAEDSSEGELDHASHTPSKRHQTLSFAESALATATRAPPTTRAAALRSNPSIASRAPPTLQSETVAHRVPVTHSREDFPYDDILYQNCVVDYDEPLLARCEPVAHNPAARIPAIIQRGGRRRPTADEICQNIQRKVREKLERMQAEKSVAGAEASSVPASYQAPDYKTAVTVLQFVEREAKRHQDANNLSEDDAKALFRIMQVEAISWGKKTFKKQEYGMRRLLLPGLNLRLDRIPSKYTVELRVLMDGVAEHALHELDEAATLSATSPPPPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYF4</accession>
    <name>W6YYF4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_41092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964152">
        <property type="protein sequence ID" value="EUC40594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692872.1">
        <property type="nucleotide sequence ID" value="XM_007694682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYF4"/>
    <dbReference type="GeneID" id="19123996"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41092"/>
    <dbReference type="eggNOG" id="ENOG502SSYQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1220231_0_0_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF3">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="22830" checksum="AEBA3EF39D77CE1A" modified="2014-04-16" version="1">MQIQVQLVTDEDIGLKVLRDAPAEATTEPMDIVAVHGIGAHPDDSWCKNAGTAEEPQWCNWLTKDDMLPAVAPNARIMRYGYESQWFGQEAMQHGVSTVAEQLLRALKQQRKDVPFRPLVFIAHCFGGLVVIKALLEAEQYQNEWSGLFASTTGLVFFGTPFRGTEGMNQMEMLEAARRGYHDEQLPEENAGPGLQDSGRVLLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYK1</accession>
    <name>W6YYK1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_9514</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964149">
        <property type="protein sequence ID" value="EUC40639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692840.1">
        <property type="nucleotide sequence ID" value="XM_007694650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYK1"/>
    <dbReference type="GeneID" id="19128591"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9514"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_3_1"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000297">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF182">
        <property type="entry name" value="POLYAMINE TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="42"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC40639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="473" mass="52543" checksum="17E7E84CFF0C8B18" modified="2014-04-16" version="1">MMDTKSVSNLPHPEVEVAGLDWDDVSNVDNPQNWPTWKKILHSAIPAVYGLALTMGTSTYVAGVLLVMKQFDISRTVALLPIVVYTIGFSLGPLVAAPISEIYGRLIVYRFCLPMLMVFNIIAAASNNLTVLIVFRFLAGFGGSGVLAVGAGTVADIWSQRQAGLVALTYILAPFLGPTLGPLIGAYIIDQYDNDWKWSIWVIPILCAPIAASLLFMQETSKSRIIYLKSSKTVQATQEVPITQRIGLAMLRPLHMILLEPLAFFLSLYTGFNFAMIFSFFGSYSYVYSRVYGFNLKEIGLTYIGLIVGYLLALVTVGYFDRKKYQPESQKTNGRVAPEHRLYAAMFGSFLLPVGLFWFAWTPRESVHWIVPVLAGVPFGWGTLAVFLASVTYLMDTYQATNGASAIAANGFLRFILGAIFPLFTIQMYENLGIHWAGSIFAFISLALIPVPWVFFWKGKDLRKRSSYETCSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZQ6</accession>
    <name>W6YZQ6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_40738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZQ6"/>
    <dbReference type="GeneID" id="19123938"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40738"/>
    <dbReference type="eggNOG" id="ENOG502QTD3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070319_0_0_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="GATase1_Hsp31_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
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        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
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        <property type="entry name" value="ThiJ-like"/>
    </dbReference>
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        <property type="entry name" value="DJ-1_PFPI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17124">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="252" mass="27769" checksum="01B7BEDC45BF8969" modified="2014-04-16" version="1">MAPNKKVLIILSDASSFPLYNTGSDGKTVSQDSGYFLMELAKPLSKILDAGYEVTFASPEGKEPTPDPLSVSLAAFAGNYYEKQRELDLIERMKKENGFSRPKKFSEISDEELKGFDGVFIPGGHAPLRDLGDNADLGRVLSHFHGELKPTAAICHGPWAFLSTKYGPKKEFEYKGYKMTSWSDAEEKVMETMLRGEIDKVESRLREEGADMQEGIGKSLGSITVDRELVTGDNPMAANALGDKFLEMLAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0C5</accession>
    <name>W6Z0C5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964031">
        <property type="protein sequence ID" value="EUC43360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690104.1">
        <property type="nucleotide sequence ID" value="XM_007691914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0C5"/>
    <dbReference type="GeneID" id="19123519"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38677"/>
    <dbReference type="eggNOG" id="ENOG502RAAA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1294180_0_0_1"/>
    <dbReference type="OrthoDB" id="3795253at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="214" mass="22328" checksum="0CC6BCC730AEAECA" modified="2014-04-16" version="1">MTSRPSFMPPTEGSFLSSGSFTPSGLTPSTRNQAEEALTANSTAQTDSAAPDPRLLPLMGSGGGNETPTQDGPAEALKAYTGYRRPGVVRASSTNYENALKRAQEASVSSDLSTDSEVPDNINNGQTVASPVSISTPFPLPGQGVVPLNYNSPVGLSQGDSQKKSRSRGLSLSGLAQQQGWTEQDYKRIYSAELMAADPKHSAGYGSAPKTETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1H3</accession>
    <name>W6Z1H3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_95154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_95154"/>
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    <dbReference type="OrthoDB" id="10494724at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="70" mass="7812" checksum="B6A306127BD89359" modified="2014-04-16" version="1">MSLCIPPTPPLSPGESSKRIHATRIFCGLNPIWRHLVFVFISANTYIPRTVRSPHTYDFSLSCPKAVNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2L0</accession>
    <name>W6Z2L0_COCMI</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_25872</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC45992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="19120836"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25872"/>
    <dbReference type="eggNOG" id="ENOG502SRIH">
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    </dbReference>
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    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="370" mass="42058" checksum="EB6B8ED999BF5955" modified="2014-04-16" version="1">MASLALIRSLRLTLPRHTAARFTIVTNNHRHSQRCSLSTRATFHYLEDRPEYQTVKPYHINIPERAFDPGLQSNEVSIAYHDIPVTGLRNRIGDFTLDRNGFKVVIEDEDRGGEMLCRALPYEEYADEASVRDRARKAVEEFLKRNIDGCEDAVAFSHQVRRRDRLFPMLPRGTSGAVPQPVQGVHVVCGALLDMTPDGSHSEVQDALAARGYTDMSKRRWAVVHIWRPLFGPLQDWPLALMDYTSLDKARDLISSDNIYVHRIRENYNVLWNKRHKWYFLEDQQPNEILVFKTFDTHATKGHARLCAHASFRNPLAAPTARPRESFECLSVVIFPEGSAASNSFEEPLPAETPPGLLGEKLAEMKGGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2P5</accession>
    <name>W6Z2P5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964009">
        <property type="protein sequence ID" value="EUC44200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689271.1">
        <property type="nucleotide sequence ID" value="XM_007691081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2P5"/>
    <dbReference type="GeneID" id="19123354"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37926"/>
    <dbReference type="eggNOG" id="ENOG502QSKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="41579" checksum="176203DDD92CF02C" modified="2014-04-16" version="1">MSAAPTSASGPQQASPPPATSSQPQPPQQQQPPTTTAPQADVGNLQSVLHLDVDTAANSDDDSAFDNESSASTSLASTILNYEYLNGRRYHGYRSGAYILPNDEQEQDRLDLQHHVFLLILQGKLYDAPISPSPQRVLDIGTGTGIWAIDFADEFPGAEVIGTDLSPIQPTWVPPNVKFYIDDAESEWVYSPAEAFDYIHCRNMSGGISDWDKFVRQTFTHTKPGGWVEFQEPLAQADCDDGTIDMAKDFLQWQTLCHDAAATWGRDIRAGIGIKQQMLDAGFVDVHEKVVKIPLGPWPRDPRMKEIGRYQREHMSMGVEPYTLGLLGKVAGWTEEECCVMIARVVSDVRRRDVHMYIKFYFVHGRKPDHSGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z399</accession>
    <name>W6Z399_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_98900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964010">
        <property type="protein sequence ID" value="EUC44183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689341.1">
        <property type="nucleotide sequence ID" value="XM_007691151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z399"/>
    <dbReference type="GeneID" id="19129353"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98900"/>
    <dbReference type="eggNOG" id="ENOG502STSC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_518747_0_0_1"/>
    <dbReference type="OrthoDB" id="3800261at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889665" evidence="2">
        <location>
            <begin position="19"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="531" mass="54634" checksum="E5E34DFB3354EF7E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3A1</accession>
    <name>W6Z3A1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anaphase-promoting complex subunit CDC26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_37713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </dbReference>
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    </dbReference>
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            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6946" checksum="01653BC94068EBAA" modified="2014-04-16" version="1">MLRRTPTTITLTQNDIEQWEAVRQRKLYEAKQQQAEQEQQAASREEAKARSKKDRIMGA</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="128" mass="13744" checksum="B87F0E27CC0C7CA0" modified="2014-04-16" version="1" fragment="single">TVASILPFSPYIGDQTCSSTSSSLLMLIVHCRPFRSRTTASAWGEAQTKILAQACSSGNLLLMCSLTSSHVELISSMVSKWLGRSVSIVSKRKGVSHLLAFMASWKSSCRSVPYNIGALALLVAFTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z433</accession>
    <name>W6Z433_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_37687</name>
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            <taxon>Dothideomycetes</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="4120989at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="324"/>
        </location>
    </feature>
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        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="395" mass="44344" checksum="A870B87B62357CCD" modified="2014-04-16" version="1">MDASTRLYKRLGEIPEDPNHPDSLDDLIVCAFGAFERYYLCWKTKGGEYKQDGYELPPALKDWLYPSDGTTRDFDSLQVVFGRGEEYFASDKNGKLEYKEPEVRKLALADDEEKHDKQALRRSRTVSFLRPLSETSVRSDSVMSETRRSNRSSSISSQRTSRPPSLTYTNSRTNSEISLLGDTIIEGQTSQPVRPSYLSQWSAMAPNVKGEEHELSPKNRTGQQLESNLGKVQEHTRTDSLVTPTMPPQPQPTSTTNTRSQPTTTTTLAPSHCTCGCHHSQPASSPPKPTYANATTQTSPPPSPHRNPPSLTIDPTPPYWQTQPAYPPDEYYYEEDDYAAPPVLMGRMSSYFNKPGYQLGDSLFSGYQPINWGQPVTNAVETYVYQDSFGDEALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4P6</accession>
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        <recommendedName>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4P6"/>
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    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="432528at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
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    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="512"/>
            <end position="578"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="696"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="11"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="696"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="711"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="727" mass="80028" checksum="54BC42EFF8B62AAD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4Z1</accession>
    <name>W6Z4Z1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_97295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688707.1">
        <property type="nucleotide sequence ID" value="XM_007690517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4Z1"/>
    <dbReference type="GeneID" id="19129030"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97295"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019225_1_0_1"/>
    <dbReference type="OrthoDB" id="2915840at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="568" mass="64190" checksum="40351FA2ACB5EA2D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5B6</accession>
    <name>W6Z5B6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_26818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688526.1">
        <property type="nucleotide sequence ID" value="XM_007690336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5B6"/>
    <dbReference type="GeneID" id="19121008"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26818"/>
    <dbReference type="HOGENOM" id="CLU_921291_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="302" mass="32922" checksum="FF929DA778153C1F" modified="2014-04-16" version="1">MAMGLFTQSGLHFPNTIDLPQGSTQCVWAKKGAGKESWAGCEDKVPRGAGPEFGFVGLVQSHDIMVPRSKTLKISKCSPWERRIGGQAGGRGAPFSLCRAQQQRGRGPKHITRVSGLPRGDAAPARIHCKSPAYTHPTGARVKANDDARIRTSWKLPFKRATATTDMFASDRPKQPSACNCPQTRRRWSRLHGSEAYTYRASALPAPAPAPAPIPHIFAFACACACDRVSGAPTYSHKEPGYSKGGHYRSNCPRDDGTCTQMGVALQPHYPQHTARLVWTRRTQHKEGRFAVPHALASGYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5E8</accession>
    <name>W6Z5E8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_91254</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC46997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686508.1">
        <property type="nucleotide sequence ID" value="XM_007688318.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z5E8"/>
    <dbReference type="GeneID" id="19127845"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91254"/>
    <dbReference type="eggNOG" id="KOG0065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_35_0_1"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001465">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="491"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="576"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="610"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="633"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="712"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1144"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1168"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1209"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1254"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1279"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1313"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1403"/>
            <end position="1425"/>
        </location>
    </feature>
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            <begin position="101"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="801"/>
            <end position="1050"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
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            <end position="795"/>
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            <end position="792"/>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1437" mass="160138" checksum="9343C509E7CA8AB8" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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    </dbReference>
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            <dbReference type="EMBL" id="EUC45205.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="613" mass="69168" checksum="D2F23D89FD7001F2" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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    </evidence>
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</entry>
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    <name>W6Z6A9_COCMI</name>
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        <recommendedName>
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            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the putative lipase ROG1 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="8">
        <location>
            <begin position="87"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="261" mass="28687" checksum="05EE1CE9E963B0C6" modified="2014-04-16" version="1">MCAFKLSNHSIVAVHGINGEPFTTWTDAGGSGNLWLRDFLPKAIPSSRIFTFGYTADFFSRSDMNILDCARSLLAGLDSQRTDGDELRPLVFIGHSLGGLVIKAALLEAKEKENPTWDAVRHGGVMFMGVPHDGAKLASFASSVSMIANIYSSTNTKMLKQLKSDSRDLWELSRRFGNIQKYLRLVSVLEAERTVSGSGRGSIKVVHDDSARLNLGEDEYKIDGSDHSTVCKFGDANNPEYIKVQNSLKKLTQPTQPVSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6H4</accession>
    <name>W6Z6H4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_36884</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963985">
        <property type="protein sequence ID" value="EUC45408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689901.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19123133"/>
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    <dbReference type="eggNOG" id="KOG2202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059852_1_0_1"/>
    <dbReference type="OrthoDB" id="423462at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="C:U2-type prespliceosome"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="C:U2AF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="entry name" value="RRM_U2AF35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000066">
        <property type="entry name" value="Splicing factor u2af 23 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009145">
        <property type="entry name" value="U2AF_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12620">
        <property type="entry name" value="U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01848">
        <property type="entry name" value="U2AUXFACTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="44"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC45408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="24462" checksum="DC6987665347493C" modified="2014-04-16" version="1">MANYLASIFGTEQDKVNCSFYYKIGACRHGDRCSRKHVKPSYSQTILLPNLYQNPAYDPKNKMNAQQMQMHFDAFYEDIWCELCQYGLVEELVVCDNNNDHLIGNVYVRFKYEEDAQKACDALNSRWYAGRPIYCELSPVTDFREACCRLNSGEGCVRGGFCNFIHRKEPSPELDRELDMCTRKWLKERGRDARSMSRSPTPPATAAKTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6Z1</accession>
    <name>W6Z6Z1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MmgE/PrpD family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_38737</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpD family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964033">
        <property type="protein sequence ID" value="EUC43319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690165.1">
        <property type="nucleotide sequence ID" value="XM_007691975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6Z1"/>
    <dbReference type="STRING" id="930090.W6Z6Z1"/>
    <dbReference type="GeneID" id="19123535"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38737"/>
    <dbReference type="eggNOG" id="ENOG502QVEB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026574_2_1_1"/>
    <dbReference type="OrthoDB" id="10267976at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4100.10">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.120">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036148">
        <property type="entry name" value="MmgE/PrpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042183">
        <property type="entry name" value="MmgE/PrpD_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042188">
        <property type="entry name" value="MmgE/PrpD_sf_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005656">
        <property type="entry name" value="MmgE_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045337">
        <property type="entry name" value="MmgE_PrpD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045336">
        <property type="entry name" value="MmgE_PrpD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943:SF8">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19305">
        <property type="entry name" value="MmgE_PrpD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03972">
        <property type="entry name" value="MmgE_PrpD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103378">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MmgE/PrpD N-terminal" evidence="2">
        <location>
            <begin position="5"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="MmgE/PrpD C-terminal" evidence="3">
        <location>
            <begin position="272"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="48245" checksum="E50093611096F5FE" modified="2014-04-16" version="1">MATLQLASWATNLTYSSLTSSVLAAANKSFFNWAGCAIGGFPFQAAPQIALNVTLSAFSGPPTSSILGANDSTSQALGDAQTAALINGITSHVDDYDDTHLETIIHPAGPVASALLAVAEAHGPITGHEFITAFVAGIEAECKLGLSVSPEHYDVGWHITSTTGSIGAAVGVSKLLRLNTTHMQHAIGIAATQVVGMQVYFGSDTKSFHIGRAAQGGILAALLAKNGYTSSLEALEAKYGWLHVVSTRENATAYFDQLGKIWEIEKNTFKPYPCGIVMHPTIDAAIYLRNETLLRSRSIEDIDTVQLRVNPEVLILTGKKEPRTGLEGKFSIYHAAAVGLVYGEARPTQFTDGVVKDPTVISGRNKVTATEDEGVSRSEAYVTLTFKDGTILQKHIEHAKGSIQNPLTEEELKKKFIEQVSLAIGPDRALGAYASFSNVLEMSDVAAIRHTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z779</accession>
    <name>W6Z779_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_36642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687818.1">
        <property type="nucleotide sequence ID" value="XM_007689628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z779"/>
    <dbReference type="STRING" id="930090.W6Z779"/>
    <dbReference type="GeneID" id="19123078"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36642"/>
    <dbReference type="eggNOG" id="ENOG502TDDT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_819257_0_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037381">
        <property type="entry name" value="RFWD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16047:SF7">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RFWD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16047">
        <property type="entry name" value="RFWD3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="338" mass="37804" checksum="BDF0D940657A1378" modified="2014-04-16" version="1">MERFINTQLHPVDACSICTEPFSTTHQPVALPCQHIFGHNCIKKWLTGGRGNTNACPTCRHILVPKSNPRGSFNVQSIWEELCHQPNERLQVFMQKLWPSLQTLWKIHPNGSFSITSMLNRALFPALTHTIRTTRPSPGPSPDPVLDCYNLISASWDSLGRPDIATGLAIPLVRLARLTANAGAVLPKYLTTSSRTNRLIWRANACLPLAADHISWDFIMQAAAPASIRYFDLLHLYTVLISQGIAHFPAPHPFPTRRHEVVNLVVERCCSKIGSGGCAWRGRPSAEFKDVLVGVYEELRKWQGEMGRMSLRGSYEEEGVVRGVWAIAAWGKERPVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7E2</accession>
    <name>W6Z7E2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964027">
        <property type="protein sequence ID" value="EUC43494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689968.1">
        <property type="nucleotide sequence ID" value="XM_007691778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7E2"/>
    <dbReference type="GeneID" id="19121224"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28020"/>
    <dbReference type="HOGENOM" id="CLU_622538_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="440" mass="47306" checksum="138A7726C1859732" modified="2014-04-16" version="1">MAWLPDTLAPKPDAEDHVGATLEMVPCWAKPYRIGAKSTRPRCMVANQGWRYCGNAPKHPGPEGKSKSYHQLPVWRRREWMSSCRPIHGGETGVSEDWGPESKRHDTSEACAGPGASPLHCQGGVQGGRSSVLERVKAKPSVEANITDGAQGCDGEAKCRQRHVCFVLACQLVLALQGLVGPGPGPGSSTHLGMRRRFLATHASAQTWFRYHKNGQALAMAMAIEAKASNVDVPAPLAALAYLGPASVRGLLGEVSEETCLRTRTLIAKPASIVVGCVLDVCVQVHGRVIFLAMCRSGPTQSCACARACACALTSPGHGRWPHDEALWRTWIERDGWLVSLVVQADRWAWEWAAKVVRLSGVLVHAWLFPSYVSQPWCRSACTHGAREGSATHLAGSCPRSSGSVAWLRGHLPLASPKPTTKLWPIGPSTLTVALNGPCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7Y0</accession>
    <name>W6Z7Y0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mannose-P-dolichol utilization defect 1 protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_4742</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the MPDU1 (TC 2.A.43.3) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963971">
        <property type="protein sequence ID" value="EUC46115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687324.1">
        <property type="nucleotide sequence ID" value="XM_007689134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7Y0"/>
    <dbReference type="STRING" id="930090.W6Z7Y0"/>
    <dbReference type="GeneID" id="19124360"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4742"/>
    <dbReference type="eggNOG" id="KOG3211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053568_0_1_1"/>
    <dbReference type="OrthoDB" id="271506at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000006">
        <property type="entry name" value="mannose-P-dolichol utilization defect 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016817">
        <property type="entry name" value="MannP-dilichol_defect-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226:SF2">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023381">
        <property type="entry name" value="MannP-dilichol_defect-1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="251"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="256"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR023381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC46115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="291" mass="30761" checksum="C638427E2A120C34" modified="2014-04-16" version="1">MEALQSTLQPLTRALPQPIADIGISLLGPSCYQTLIYNVDLTATDCVKLAISKGLGIGIIGASSIVKIPQLVKLLNSQSAEGLSFLSYLLESSSYLISLAYNVRHGFPFSTFGETALILVQNIAIASLVLKYSGKGVGIAAWVGGLMAAGAALFNEDLVGEDKLALLQASAGVLGVASKVPQILTVWSEGGTGQLSAFAVINYLLGSLSRIFTTIQEVDDPLILYGFIAGFCLNVILFLQVMYYWNAPASKKTQSKKLEKPIIAGGEKKEATRSVSTGRAAGKSPSTRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z925</accession>
    <name>W6Z925_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_99215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964012">
        <property type="protein sequence ID" value="EUC44059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689407.1">
        <property type="nucleotide sequence ID" value="XM_007691217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z925"/>
    <dbReference type="STRING" id="930090.W6Z925"/>
    <dbReference type="GeneID" id="19129423"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99215"/>
    <dbReference type="eggNOG" id="KOG1360">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015846_3_0_1"/>
    <dbReference type="OrthoDB" id="2382073at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF77">
        <property type="entry name" value="8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="5">
        <location>
            <begin position="64"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC44059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="526" mass="58112" checksum="E3AD3D06AF2610E6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z982</accession>
    <name>W6Z982_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_87858</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685273.1">
        <property type="nucleotide sequence ID" value="XM_007687083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z982"/>
    <dbReference type="GeneID" id="19127143"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87858"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_0_1"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="57693" checksum="3A613FFE21649B57" modified="2014-04-16" version="1">MDSQIFSESALIAQVTTLSALVITFLALLPKLSLQFKLSKLPVFGLSTNNDKQRAFFLKYCTELYRKGYTQFTRSVYRMAADDDIQYVVIPPRFLPELNKLSDDVVDLPAAVKKMLEGHYTKHETNFPTLMHSIKADLTPSLKRLNEHVSAEVDNAMERFMPPCEDWTKLTIYESVTNIIAQVSGRLFVGPEHCRDPEYLDIAVNFTNETTTAAFAVKNCNKWLRPFKASHLSEVQHLQNRYERATKFFQPILHQRQESDRKNFDDMLQWLTDRAKSSGVPMEISSLIRQQLTLTVAAVHTTAMTATNSLFSLAAMPEYLEPLREEIQTVLDGNGGSLTPRALQQLVKLDSFIKEVGRWYPFSITSFARYVHKPFILSNGQHIPAGVIIEVPSDAVSFDPAIFTNPNEFDGFRFYKMRENAGTGELARSQFVSANERDMLFGYGKHACPGRFFAANEIKMVLVRMIMDYDIVMPDGRKERYEPLQVDRQVMPNPSNSLLLRRRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9D4</accession>
    <name>W6Z9D4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone deacetylase complex subunit SAP18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_35743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686831.1">
        <property type="nucleotide sequence ID" value="XM_007688641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9D4"/>
    <dbReference type="STRING" id="930090.W6Z9D4"/>
    <dbReference type="GeneID" id="19122858"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35743"/>
    <dbReference type="eggNOG" id="KOG3391">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064128_0_0_1"/>
    <dbReference type="OrthoDB" id="440566at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.550">
        <property type="entry name" value="ASAP complex, SAP18 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010516">
        <property type="entry name" value="SAP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042534">
        <property type="entry name" value="SAP18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13082:SF0">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13082">
        <property type="entry name" value="SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06487">
        <property type="entry name" value="SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="28446" checksum="4C3BD2E6C308D39D" modified="2014-04-16" version="1">MAAPAKIDRQTTTPFLLRLFFKQGSFHRLDEFDPTLPRLPTNVQIYTWQSCTLRELCQLLLSAVPSMLPQPYAGSRIAFRLVYPDIQGSNRPGAPGRFISRDIGSVIVGAPSRNDDVDMEMNEGGSVAEALKQLDGDPDRTLADVKFLIGDYIACAILPPLPDGGVPAAPPPLSGPGRGPPAGSYGGRGRENGFGGRGDWGGYGRGGRGGGGGRFDDRRLSGGGVPSGEWRRGEVPPERESGFGRGGRGRGGGDDWRDRGRGRGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA89</accession>
    <name>W6ZA89_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_91543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686576.1">
        <property type="nucleotide sequence ID" value="XM_007688386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA89"/>
    <dbReference type="STRING" id="930090.W6ZA89"/>
    <dbReference type="GeneID" id="19127902"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91543"/>
    <dbReference type="eggNOG" id="KOG3043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_2_1_1"/>
    <dbReference type="OrthoDB" id="10019231at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF55">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G01900)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="243" mass="26798" checksum="8A3A3DC566032412" modified="2014-04-16" version="1">MSCDNCKSGFKWNGQTVGKETKLNNANAYVTGDNKDAAILIITDLFGWTLPNVRLIADHYAQEANATVYVPDLFDGEVVDPDALSDPEKQKNFDIGAFLGRHNKEVRFPEIKGHAQTLKSQYKKVAAIGFCYGGWAAFKLAADPALVDAIATAHPSLLEKSEIESVKVPVQILSPENDFAYTAELKQATFDILPKTGVQWEYIYFPGLTHGFAVRGNPNDAAQKAGLERAKRSAVNFFKEFLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAE1</accession>
    <name>W6ZAE1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_6200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688971.1">
        <property type="nucleotide sequence ID" value="XM_007690781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAE1"/>
    <dbReference type="ESTHER" id="cocsn-m2rnk8">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="19124877"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6200"/>
    <dbReference type="eggNOG" id="KOG4389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_7_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="80"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC44499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="630" mass="70563" checksum="0965729D56463D69" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAJ8</accession>
    <name>W6ZAJ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_3999</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="2"/>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC47005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686456.1">
        <property type="nucleotide sequence ID" value="XM_007688266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAJ8"/>
    <dbReference type="STRING" id="930090.W6ZAJ8"/>
    <dbReference type="GeneID" id="19123786"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3999"/>
    <dbReference type="eggNOG" id="KOG2007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013528_3_1_1"/>
    <dbReference type="OrthoDB" id="438179at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000186">
        <property type="entry name" value="Putative Cysteinyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF3">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="13">
        <location>
            <begin position="42"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="756"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="703"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="764"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC47005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="800" mass="89544" checksum="8F09D040307B2D15" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAN2</accession>
    <name>W6ZAN2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_97966</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688966.1">
        <property type="nucleotide sequence ID" value="XM_007690776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAN2"/>
    <dbReference type="GeneID" id="19129158"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97966"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000217">
        <property type="entry name" value="MFS lactose permease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF70">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14540)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="59"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC44569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="537" mass="59272" checksum="5B1BA41233EC9EA0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB37</accession>
    <name>W6ZB37_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine cleavage system P protein</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_3870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GcvP family.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686299.1">
        <property type="nucleotide sequence ID" value="XM_007688109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB37"/>
    <dbReference type="STRING" id="930090.W6ZB37"/>
    <dbReference type="GeneID" id="19123527"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3870"/>
    <dbReference type="eggNOG" id="KOG2040">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_3_2_1"/>
    <dbReference type="OrthoDB" id="6537869at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016594">
        <property type="term" value="F:glycine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000005">
        <property type="entry name" value="Glycine dehydrogenase (decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000007">
        <property type="entry name" value="glycine dehydrogenase (Decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000007">
        <property type="entry name" value="Glycine dehydrogenase (decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049316">
        <property type="entry name" value="GDC-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049315">
        <property type="entry name" value="GDC-P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773:SF1">
        <property type="entry name" value="GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="GLYCINE DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21478">
        <property type="entry name" value="GcvP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="8">
        <location>
            <begin position="93"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="8">
        <location>
            <begin position="582"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine dehydrogenase C-terminal" evidence="9">
        <location>
            <begin position="886"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF21478"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47160.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="1077" mass="117210" checksum="E78D2263AF1BB7AF" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="139"/>
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            <end position="169"/>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
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    </dbReference>
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        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF9">
        <property type="entry name" value="MEAB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
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            <end position="80"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC49397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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        </source>
    </evidence>
    <sequence length="423" mass="46601" checksum="7ACC349AF6EDD87B" modified="2014-04-16" version="1">MTAPVGKVEAQRDGSTSSIGSSPEPGLAEPYPQEEPQQQKRKGGLATASMIELTRPRKIYATSEERKQRNRQAQAAFRERRTEYIKQLENTIKHHEDTLQNLQNSHRNAADECLMLRYKNSLLERILLEKGIDVQAELRAKTGSPNLGATRPPLSAHASPNQAPLQQRAMLNRQQQRRSLQGPPKIDASNGLPMIQPDGPIQRSPLTQPTPGSHLSSPAQSATRSPNFMPHGQSVSPNFGPMHSQQQQQQQQQQQPQQQQPLRPQPPRSNFTPMMGAQRPSLVTNQPSSNGMSNASTVGNSGNGVAPNNGPSSFYQTQFTDHMKQEYEEQADSYDHDDPSDQSAGPGPFPQQNFPPSNNMPPPMPPSQNPPFTSPAALAPNDGGQVFNGMSNNHLFDPYDPMLDADPFGLSASMHFPTMYESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC93</accession>
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            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687936.1"/>
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    <dbReference type="STRING" id="930090.W6ZC93"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="225"/>
        </location>
    </feature>
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            <end position="281"/>
        </location>
    </feature>
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        <location>
            <begin position="296"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="435"/>
        </location>
    </feature>
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            <end position="183"/>
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            <begin position="1"/>
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        </location>
    </feature>
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        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
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        </location>
    </feature>
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            <end position="279"/>
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    </feature>
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        <location>
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            <end position="329"/>
        </location>
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            <end position="344"/>
        </location>
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            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="435" mass="48039" checksum="9C8EE8BE25A680FE" modified="2014-04-16" version="1">MRTPSPPTPQLTSPPPTTKLPDQASALADLGAGLYPQDQVNSASVQELRAMVNSLSNALRDMRLSAAHYKLQHNMAVMESQEAASRMAVELAMAQRELDVLQQAEEKRRATMAAPEQTYQDSANAVMVSELTRQNQVLQSENDELREMLEQQKRLTEHREGELASLIEENDRLKTRIRNNRDHIAPLLEQIEQSSPRSTFGTPAQPTPRNRLNRVPPPPLSQQNRSQSNFEALLLADKMLSQDASTAPSTPNRVQAPRARFSHQRGAQSMSSLPQTPNQRAAFPRAEVPRTPPLFAPTNIPQSAPPVHYQQKPESIRRQSSNSTITASSIDEEEAFTDREDDQVPESQASQMARSLLQQPPPAKGIMSAPASQPSNLVQSKIFGQVKKGHGLTRANELKRGRMPSTADLRNQTSPPKRGRVDQGVGLGIGGLLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCA3</accession>
    <name>W6ZCA3_COCMI</name>
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        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_96658</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963992">
        <property type="protein sequence ID" value="EUC45059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007690264.1"/>
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    <dbReference type="STRING" id="930090.W6ZCA3"/>
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    <dbReference type="eggNOG" id="KOG0598">
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05578">
        <property type="entry name" value="STKc_Yank1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AGC/YANK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Serine/threonine-protein kinase 32B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
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    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355:SF30">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 32B ISOFORM X1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="521"/>
            <end position="551"/>
        </location>
    </feature>
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        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
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            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
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        <location>
            <begin position="442"/>
            <end position="456"/>
        </location>
    </feature>
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            <end position="469"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="540"/>
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        </location>
    </feature>
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        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="563" mass="63017" checksum="00DA481ED16C34F2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCI9</accession>
    <name>W6ZCI9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vegetative cell wall protein gp1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_89924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685928.1">
        <property type="nucleotide sequence ID" value="XM_007687738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCI9"/>
    <dbReference type="STRING" id="930090.W6ZCI9"/>
    <dbReference type="GeneID" id="19127577"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89924"/>
    <dbReference type="eggNOG" id="ENOG502SK85">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039952_1_2_1"/>
    <dbReference type="OrthoDB" id="5398854at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="46990" checksum="1E829DFF4AAB05B9" modified="2014-04-16" version="1">MYAPQYPTPPPGYMPYDYHRTTPPMSPGPGANYYSPRHAPQMATPRASPKVSGHSRRASHAVPSTQYQQYTASPRGGAVPHYGAAEFAAPRTHATPRGTPEYVSYFGYTLPSRHRRDSDVPPLKRSHRERKRRSSQSARQVHTRVVYDDRGYGYECDYDVYDYPPPPYEQYARHDMYRGDADRYYYDQVPIYDPEPKSSRPRRASASTRQPAASPKKPAPTKTSPKATEEDARRAGIPAGYSYKNWDPTEEPIMLLGSVFDANSLGKWIYDWTVFHYGPATPLAEMAGELWLLLIQLAGKVKRADETMPKIRKKENHEMVEDFLESGERLWVRFAKLLKVCEDYMWKAAKKESGKEKPVSMGKNSGKEFVESIFGRDRELEKTEKLMTGMRLWSMRFDANCEDILRYPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD85</accession>
    <name>W6ZD85_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963985">
        <property type="protein sequence ID" value="EUC45399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688105.1">
        <property type="nucleotide sequence ID" value="XM_007689915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD85"/>
    <dbReference type="GeneID" id="19128704"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95664"/>
    <dbReference type="HOGENOM" id="CLU_816340_0_0_1"/>
    <dbReference type="OrthoDB" id="3692151at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="333" mass="38876" checksum="9588655CD3EAEA0F" modified="2014-04-16" version="1">MFRNILDMLRAYREKQKQTKNADKEWDEWNEWNDDIRTVPYALDHCTQHCRHPICRRVIRGNERINLDQEACQCSLEPPPATTSKYQVPIQEFSEEDIAAVQSTYDHTSKHDLITVNLGTAITLVDLLRQNFHLNLCSRLQWDPRFTPNTLLHGTQYNAAVQSTNGLVDKLFVHLMLLLGPTPNQTRCIELQELQQTLQSVMRLEFFWWQATWCFKQQQQQQQQERIAKADDSHVRKMMKDGFVRARRRYICGRQSVGIRVMMEKLEDIVEMVVGVLVWWSECTRRWAEEEKEEEDEDAESTGLDSSVASFVTAQSHVTGDDSDVNGRDGEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDB8</accession>
    <name>W6ZDB8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF985 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_22584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683631.1">
        <property type="nucleotide sequence ID" value="XM_007685441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDB8"/>
    <dbReference type="GeneID" id="19120282"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22584"/>
    <dbReference type="eggNOG" id="ENOG502RM2D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088365_1_1_1"/>
    <dbReference type="OrthoDB" id="6614653at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06121">
        <property type="entry name" value="cupin_YML079wp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009327">
        <property type="entry name" value="Cupin_DUF985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039935">
        <property type="entry name" value="YML079W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387:SF3">
        <property type="entry name" value="DUF985 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387">
        <property type="entry name" value="RMLC-LIKE JELLY ROLL FOLD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06172">
        <property type="entry name" value="Cupin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886899" description="DUF985 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="DUF985" evidence="2">
        <location>
            <begin position="27"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="168" mass="18836" checksum="150CA7078B1D74C3" modified="2014-04-16" version="1">MKKSSSIWFAISLLGVSASHRDGLSAQDVIDRLHLEPNPEKGYYRQTFEDASNLNNRSYSTAIYYLLEGEVGPSYWHRVVDAVEIWHYYAGAPLQMDLSWNNGTATEHRLLGNDFFANHSPQVVIEKGRWQRATSLGTWTLVGTTVAPGFSEEGFELPGPGFEPNDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE13</accession>
    <name>W6ZE13_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_83059</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683473.1">
        <property type="nucleotide sequence ID" value="XM_007685283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE13"/>
    <dbReference type="GeneID" id="19126179"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83059"/>
    <dbReference type="eggNOG" id="KOG3020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031506_1_0_1"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000072">
        <property type="entry name" value="Hydrolase, TatD family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="313" mass="34451" checksum="B709B904E531A813" modified="2014-04-16" version="1">MAASTQLKYIDIGINFTDPIFRGEYHGTQRHENDFEDVLQRAVDAGCKKFMVTGSDLEESKHAIEIAKAHPGLCYATVGVHPCSANHFDKHPGGASELLSALKSLAVEAKEAGHAVAFGEIGLDYDRLFLTAKEPQLKYFEAQLEIAIEVQLPLFLHSRAASEDFERLLTAKLDQLPKRGLVHSFTGTAQEMQHLVDLGFDIGVNGCSMKTDENIAVVKQIPLERLQIETDGPWCEMRPSHASAKFLTDAPPLPKAVKKEKWAKGMMVKGRNEPATIPHVAYAIAKIKEISVEEVCDAAWKNSVKMFGLGEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEZ5</accession>
    <name>W6ZEZ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pirin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_4823</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963972">
        <property type="protein sequence ID" value="EUC46084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687391.1">
        <property type="nucleotide sequence ID" value="XM_007689201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEZ5"/>
    <dbReference type="GeneID" id="19124392"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4823"/>
    <dbReference type="eggNOG" id="ENOG502RXW4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064194_3_1_1"/>
    <dbReference type="OrthoDB" id="10261807at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02910">
        <property type="entry name" value="cupin_Yhhw_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212:SF3">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="19"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="267" mass="29587" checksum="A945F30EA3416843" modified="2014-04-16" version="1">MSTATPASLKITKRPWSQRGHADHGWLYTYHTFSFASYYDPRHESWGPLRVINEDRVEAGTGFGTHSHAEFLIFSYIVSGTLEHKDSMGNLENLQRGEVQFTSAGTGIRHSEYNRNRDSEVHFLQIWAKPNKRGLKPHYETKKFSDEEKKDRLVRIMESTDRLAKSEGAIGLQADLSMDASILGPGKKVVHEIVAEGPRKLFAHVVMSGRTQPKTGGGAQIKIGETILGEGDGAYIDGAKGPGKIEIESVGDKDAEFLLFDMGPEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFZ4</accession>
    <name>W6ZFZ4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_21748</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFZ4"/>
    <dbReference type="STRING" id="930090.W6ZFZ4"/>
    <dbReference type="GeneID" id="19120115"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21748"/>
    <dbReference type="eggNOG" id="ENOG502RYA1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054222_0_0_1"/>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12526:SF510">
        <property type="entry name" value="D-INOSITOL 3-PHOSPHATE GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12526">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="4">
        <location>
            <begin position="351"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="485" mass="53961" checksum="E4EE475D8C3B7F23" modified="2014-04-16" version="1">MLYQSPVHSSSSSALSSSTVSDTSTSGPSLFPMRVFLVQTARGLFSSSGGYKANICLLRYLASRGHSVRQLCYSYHGEVEMYTQIIAKGGGRDMNLHKRLLHLRGENNAAGTDVTVHEFVMDDGVQIVALDSDEFDAAFGGKKNIHKAMTRETADLIETGTTSARLQDFVSFLQQEITMFMPTHIISNDGLSMQATSALQMPSLSVCRVGIVHTAEQLPFGPFAGGLPGHASSPGESKLLQNLDGIWSVSDAIKKYALEHGRLRTSFFVHHPWTYLEETSHRIPAHLHNWDKKFVCMINPCVVKGSPIFIDIAKACPQHDFLVYKSWGFDDVIGKRMEELPNITIRPACTNMEEAWQDIKLLLVPSLWLEAWGIVLVEAHLRGIPVISSSSGALPEAMLGLDHIVPVNPINGDRDEEGAYIVPPQDIRPWVKTVNRLMNNRSEYENLSIAVREKTVQWLKDMDEMALENWLAHLAIDSNGYRTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG36</accession>
    <name>W6ZG36_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964060">
        <property type="protein sequence ID" value="EUC42466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691016.1">
        <property type="nucleotide sequence ID" value="XM_007692826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG36"/>
    <dbReference type="GeneID" id="19118296"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103413"/>
    <dbReference type="HOGENOM" id="CLU_3037808_0_0_1"/>
    <dbReference type="OrthoDB" id="3683942at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="55" mass="6469" checksum="B5BCDF18815B57C0" modified="2014-04-16" version="1" fragment="single">RLAQSVERETLSLSRSNRHDYSVHLKVVGSTPTSGLYVLFLLFIIHPTYSWFLFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG51</accession>
    <name>W6ZG51_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Arabinan endo-1,5-alpha-L-arabinosidase</fullName>
            <ecNumber evidence="4 7">3.2.1.99</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_7962</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Endohydrolysis of (1-&gt;5)-alpha-arabinofuranosidic linkages in (1-&gt;5)-arabinans.</text>
            <dbReference type="EC" id="3.2.1.99"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.99" evidence="4 7"/>
    <dbReference type="EMBL" id="KI964060">
        <property type="protein sequence ID" value="EUC42481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690999.1">
        <property type="nucleotide sequence ID" value="XM_007692809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG51"/>
    <dbReference type="STRING" id="930090.W6ZG51"/>
    <dbReference type="GeneID" id="19125512"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7962"/>
    <dbReference type="eggNOG" id="ENOG502QTQG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009397_5_0_1"/>
    <dbReference type="OrthoDB" id="195678at2759"/>
    <dbReference type="UniPathway" id="UPA00667"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046558">
        <property type="term" value="F:arabinan endo-1,5-alpha-L-arabinosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18831">
        <property type="entry name" value="GH43_AnAbnA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016840">
        <property type="entry name" value="Glyco_hydro_43_endo_a_Ara-ase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026534">
        <property type="entry name" value="Endo_alpha-L-arabinosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887461" description="Arabinan endo-1,5-alpha-L-arabinosidase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="9">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR026534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC42481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="319" mass="34310" checksum="3D676BC6DAEAABF6" modified="2014-04-16" version="1">MRYSLVASLLSAVTAVYGYANPMECTGICNNAHDPALIRRADGTYFRFSTGGKIAIHTAPKITGPWTYKGAAIPAGSKINLPGKDDLWAPDVTLVGDTYYLYYSVSSFGSQNSAIGVATSKDLSTWNDLGSTGIQSSSGKNYNAIDGALYWDGSKFVMSFGSFWQDLFSIGMTNPPLKTSSSTVTNIAFKPEGTHAQEAPFIALNGKYHYLFFSVGKCCAFDASRPAPGEEYKIQVCRSTSATGGFVDKNGVDCTRGGGTTVLESHGWVYGPGGQGVYYDPQLGPVLYYHYVDTRIGYADGQKKFGINKINFSSGWPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGJ2</accession>
    <name>W6ZGJ2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_33660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGJ2"/>
    <dbReference type="STRING" id="930090.W6ZGJ2"/>
    <dbReference type="GeneID" id="19122377"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33660"/>
    <dbReference type="eggNOG" id="KOG0745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014218_1_1_1"/>
    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="205"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="5">
        <location>
            <begin position="468"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="163"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="66931" checksum="19505457C155D989" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGZ7</accession>
    <name>W6ZGZ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal RNA-processing protein 41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_7698</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Component of the RNA exosome complex. Specifically part of the catalytically inactive RNA exosome core complex (Exo-9) which may associate with the catalytic subunits RRP6 and DIS3 in cytoplasmic- and nuclear-specific RNA exosome complex forms. Exo-9 is formed by a hexameric base ring of RNase PH domain-containing subunits and a cap ring consisting of CSL4, RRP4 and RRP40.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964049">
        <property type="protein sequence ID" value="EUC42796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690685.1">
        <property type="nucleotide sequence ID" value="XM_007692495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGZ7"/>
    <dbReference type="STRING" id="930090.W6ZGZ7"/>
    <dbReference type="GeneID" id="19125365"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7698"/>
    <dbReference type="eggNOG" id="KOG1068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063514_0_1_1"/>
    <dbReference type="OrthoDB" id="437922at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030847">
        <property type="term" value="P:termination of RNA polymerase II transcription, exosome-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd11370">
        <property type="entry name" value="RNase_PH_RRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.70:FF:000004">
        <property type="entry name" value="Exosome complex component Rrp41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF0">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="22"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="9">
        <location>
            <begin position="182"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00063066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00077929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="254" mass="27234" checksum="B01972A82B5B85B6" modified="2014-04-16" version="1">MPLDTSTYSLALLRLDGRRWNELRHIHAQISTQAAADGSSYLEMGNTKILVSVTGPAAEGRQTGQRGGGATSDKLAKIDVEINFAGFSGVDRRKRKSDKKTSEMEHCLRSAFEGVLSLHLYPRSTITINVHVVSQDGSLLAACLNAATLALVDAGIPMTDYLVACTAASSASAEAADNASADDPLLDLNNQEELELPFLTVATLGESDNVAVCVMESRVRMERLESMLAVGIEGCKRMRGILDDVVKGYGKRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH10</accession>
    <name>W6ZH10_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="19">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">COCMIDRAFT_102515</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 19">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="19"/>
    <dbReference type="EMBL" id="KI964048">
        <property type="protein sequence ID" value="EUC42811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690668.1">
        <property type="nucleotide sequence ID" value="XM_007692478.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZH10"/>
    <dbReference type="GeneID" id="19118095"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102515"/>
    <dbReference type="eggNOG" id="KOG0210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000846_6_0_1"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000067">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000009">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF5">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 18 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 19" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="561"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1089"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1118"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1167"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1209"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1233"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1259"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="21">
        <location>
            <begin position="177"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="22">
        <location>
            <begin position="1055"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="275"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="16">
        <location>
            <position position="625"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="625"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="625"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="626"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="627"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="627"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="733"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="777"/>
        </location>
        <ligand>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22456">
        <property type="entry name" value="KH-I_Rnc1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22457">
        <property type="entry name" value="KH-I_Rnc1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049786">
        <property type="entry name" value="Rnc1_KH-I_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="43"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="129"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="283"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="223"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC49350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="365" mass="38491" checksum="B2E8F701EEEA242E" modified="2014-04-16" version="1">MSTEEPQPGPGQDATRVADQLDRLNMDGEGEVVPRTEEEYAEAQLTLRAIVSSKEAGVIIGKAGKNVADLRDETGVRAGVSKVVQGVHDRVLSVTGSLSGISKAYGLAAKGLLEGAPAMGMGGVIRTDGTHPIRLLISHNQMGTIIGRQGLKIKQIQDASGVRMVAQKEMLPQSTERIVEVQGSPAGIEKAVWEIGKCLIDDHERGYGTVLYNPAVRVQPGVGPGPAANGGSAPASGMGGGRSYNRTGHGADFSDSPPAFSRRSGSDAASRPPPPTHTEDGEEMQTQNISIPSDMVGCIIGRGGSKISEIRKTSNARISIAKAPHDDTGERMFTITGSASANEKALYLLYENLEAEKMRRSQTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIN7</accession>
    <name>W6ZIN7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="7">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_1455</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="7"/>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683612.1">
        <property type="nucleotide sequence ID" value="XM_007685422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIN7"/>
    <dbReference type="STRING" id="930090.W6ZIN7"/>
    <dbReference type="GeneID" id="19119871"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1455"/>
    <dbReference type="eggNOG" id="KOG2951">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_1_2_1"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="UniPathway" id="UPA00823">
        <property type="reaction ID" value="UER00788"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000004">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000012">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="314" mass="34263" checksum="0AC33E817A984204" modified="2014-04-16" version="1">MASTDSQGFKLALSKHGLTADHLNEIHDLLMEIAIDGGKIMVAAEHSVLAVAQYKNNTSDLVTEFDKQIEDTVESRLRNEYPAFGFLGEETFKHGTKLADTPTFVCDPIDGTLNFSKGVPNCAISLALTVDKKPVVGVVYNPFRGDLYHAVKGQGAYLKNTFTGTEIKLPIQAVPPPMPSLNSCLVAIEWGNQRSGENWALRTSVHNKLLTSKVEGGAMCKSVRSNGSAALDFCYVAQGIIDVFWEGGVWIWDVCAGWIILEEAGGIVASANPGDWDPSLEGRVYFAVRHANPEDQKAVVEELWGIMGDRKFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIY6</accession>
    <name>W6ZIY6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4211 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_83409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683593.1">
        <property type="nucleotide sequence ID" value="XM_007685403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIY6"/>
    <dbReference type="STRING" id="930090.W6ZIY6"/>
    <dbReference type="GeneID" id="19126250"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83409"/>
    <dbReference type="eggNOG" id="ENOG502S7B9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021433_0_0_1"/>
    <dbReference type="OrthoDB" id="21499at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025451">
        <property type="entry name" value="DUF4211"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14689:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14689">
        <property type="entry name" value="PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13926">
        <property type="entry name" value="DUF4211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4211" evidence="2">
        <location>
            <begin position="360"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49985.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="653" mass="74119" checksum="76A43AFD1EF98AC0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIZ7</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </feature>
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            <end position="316"/>
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    </feature>
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        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="316" mass="35828" checksum="C69340B50B3DCE82" modified="2014-04-16" version="1">MSTPDDANLRALLLLSKESLLARARESLLRGLPDDDLAELVAQMVSRDKPRGDLEEIARMMLDVLVRRDAQNDALLSLTTNDNSTAAASTEEIRVKYTSDVSPEIRTSHGRLSMRKRPASEQSVSTMEETASAKRAKHEDEDTAPSLRTWDQEQIAGKTVQVAGVVYWNPYKECYFKLALENDKDRIANLIADEFDAEYLSESDHIDTWKDMLKNPKHYMKKRWCVGRALNEKEEEFLGDDNMSTKKTTCTSCIQQQRICARLVNFAGSIKLAFFPLPPQLQCVDEIAEQGFWSQSSKYDEDDCSEDVSVTGQERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ84</accession>
    <name>W6ZJ84_COCMI</name>
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            <fullName evidence="12">Acyl-coenzyme A oxidase</fullName>
        </recommendedName>
    </protein>
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        <name evidence="19" type="ORF">COCMIDRAFT_32645</name>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
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        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2</text>
            <dbReference type="Rhea" id="RHEA:38959"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; peroxisomal fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
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    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
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    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF250">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 14" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="17">
        <location>
            <begin position="33"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="16">
        <location>
            <begin position="148"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="18">
        <location>
            <begin position="289"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-terminal" evidence="15">
        <location>
            <begin position="511"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000168"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR000168-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC50078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="694" mass="78296" checksum="06F81D04234619CF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJC3</accession>
    <name>W6ZJC3_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_38402</name>
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    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964022">
        <property type="protein sequence ID" value="EUC43671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689799.1">
        <property type="nucleotide sequence ID" value="XM_007691609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJC3"/>
    <dbReference type="STRING" id="930090.W6ZJC3"/>
    <dbReference type="GeneID" id="19123456"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38402"/>
    <dbReference type="eggNOG" id="ENOG502SIMU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_7_1"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DUF7708" evidence="2">
        <location>
            <begin position="76"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="288"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1138" mass="130387" checksum="BEF2651ADB98735F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJY7</accession>
    <name>W6ZJY7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Isoleucine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_89350</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="3"/>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685803.1">
        <property type="nucleotide sequence ID" value="XM_007687613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJY7"/>
    <dbReference type="STRING" id="930090.W6ZJY7"/>
    <dbReference type="GeneID" id="19127461"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89350"/>
    <dbReference type="eggNOG" id="KOG0433">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_7_2_1"/>
    <dbReference type="OrthoDB" id="10264412at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000111">
        <property type="entry name" value="Mitochondrial isoleucyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050081">
        <property type="entry name" value="Ile-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="13">
        <location>
            <begin position="59"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="14">
        <location>
            <begin position="756"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC47754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1021" mass="114076" checksum="AB6811604BD05622" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKH5</accession>
    <name>W6ZKH5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_88531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685525.1">
        <property type="nucleotide sequence ID" value="XM_007687335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKH5"/>
    <dbReference type="GeneID" id="19127291"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88531"/>
    <dbReference type="eggNOG" id="ENOG502S42K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047269_1_0_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF2">
        <property type="entry name" value="ALPHA_BETA-HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="149"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="393" mass="44612" checksum="EE9EE95836838D89" modified="2014-04-16" version="1">MILGQISYLDCIAFLVFLAPQLLIQIGIIPLLTWLLPQLPFLTFKVIVIPIQFIHERLFVPVEQRAPWVRKATPFQDLVIRFVRYAFANMPAFLGRVFFSKQVSLPFLRFRMLRHGVVTSPIRWTDIKRPNFKGVWIVYNQQEQPDLIVYYCHGGGFSMGSSYFYMEFLLAWVALLKAAGYRNPALFALEYTLVPDATYPTQLHETLAGYEYVLSLAQSSTRIVVGGDSAGATLMLSFLLYLSEHTELRHQKPGLAIMISPWVKIISPENRNTKSDYLNSSSLEQYGRQYIGSKVSSGDAMVSPGNCKDIQKWTEASPEKGWYFLYGSEEVLGPETRNLIALLEKTGKEVDTWEERGGIHAWPVASLYLGETKEARLSGLKSVVGAIKERIHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL32</accession>
    <name>W6ZL32_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_87950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685241.1">
        <property type="nucleotide sequence ID" value="XM_007687051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL32"/>
    <dbReference type="GeneID" id="19127166"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87950"/>
    <dbReference type="eggNOG" id="KOG2588">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_966455_0_0_1"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11395">
        <property type="entry name" value="bHLHzip_SREBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="189"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="288" mass="32049" checksum="932DD77CDC94A62A" modified="2014-04-16" version="1">MPYSNYFDNPYLSDVFDPGPDYTLNSFFDSDNFFSQPTTSIEGASNTQPKSQRTTASKLPVTILPSSSHQQSYPQTYNQPQFGQFEQYRGDFSIHPTPPQAGEHDSFSPITTVTTSHSSSHSSDAPHQAVSPSLSPHTLKRESPSSPASASESSTPKRPTRKRGRPRMSRSSTDSQLAATSPTLKSQTSRRQPHNQVERKYREGLNSELERLRRAVPLLRQNDGTSSIGQPKPSKATILASAIDYIQAIEKERDALRAEVEQLRRDQAGMLQNSDGRNPCLNEYLMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM24</accession>
    <name>W6ZM24_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_86921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684850.1">
        <property type="nucleotide sequence ID" value="XM_007686660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM24"/>
    <dbReference type="GeneID" id="19126953"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86921"/>
    <dbReference type="eggNOG" id="ENOG502SHAY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_1_1"/>
    <dbReference type="OrthoDB" id="3923077at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF21">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="30"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC48594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="355" mass="38526" checksum="244CD10E22FA420A" modified="2014-04-16" version="1">MATVPVAGDGVALLYCAIVLLALTWVTFFLRATVRIWRKAWGMDDYLMLLGILLFTVTAALCIVCCFYGSGQLSRDLPPATMAIGIKLFYIAEYFYCVSAMFIKISVAVALLRIAATRDFFKWGLWILIGACIVAALVFCIGIANICHPINTLWGESNGVCNLQVNTNVSLFYSAIEIAADFSLSILPAILLWNVQMKTRVKASVAVMLALASFASTATIVRLKYLTLYSDPGEFMFSTGKIGFWSLTEEGIGLIAGSLPALRPLLSLRIRVTVGSNTPGASSGRAYNSGSHHLQPPSRSRGIPMDNFQTLGDNDDCDNSDGDSQKNIIKETKFSVTTTATGPKSNPVMPWNANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM51</accession>
    <name>W6ZM51_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_86800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684860.1">
        <property type="nucleotide sequence ID" value="XM_007686670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM51"/>
    <dbReference type="GeneID" id="19126935"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86800"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF40">
        <property type="entry name" value="THIAMINE PATHWAY TRANSPORTER THI73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="67"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="508" mass="56287" checksum="775C9B6E755EDBDF" modified="2014-04-16" version="1">MGDFEKDVSKSGDISPSPQYSDVEIGTVHDTTKNGDSALEFLRTAHDVGELTPEEERRLLRKIDWMIMPLMWCCYCLQYLDKTLVNYAAVMGLYDDANITTDQFSNLALFFYVSYLVVEFPHGYAMQRLPTAKYLGSAVILWGLVTALTCVCKNYGALVATRVLLGCFEAAVAPSLILITSMWYKRTEQPLGTGIWYLGVGTGTMIGSLISFGFQHYHRDTFTSWQIMFLVVGLVTVAVGITVVFLLPDNPMSSRLTPSEKVWAITRLRSNQTGIENTTFKPYQVLECFKDPQTWLLSLITISSNVPNGAVSSYQATLIKSFGFDSKTTALLQLPSGAISIISILIATYLAGRYNQRGLNIVTLLIPGMLGGCLMAFLPSSAKTGKLIGNYLTNCIGSSLPLLYSWVAADYAGHTKKVTMNAVLLMSFCLGNIIGPLTFRKEDSPDFVPAKITIIITCAVAAGLAVVLRVYYGVENGKRERREVGERVENEEFLDLTDRENARFRYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM80</accession>
    <name>W6ZM80_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 6">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_21499</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 6"/>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682329.1">
        <property type="nucleotide sequence ID" value="XM_007684139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM80"/>
    <dbReference type="STRING" id="930090.W6ZM80"/>
    <dbReference type="GeneID" id="19120072"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21499"/>
    <dbReference type="eggNOG" id="KOG0169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002738_1_0_1"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16207">
        <property type="entry name" value="EFh_ScPlc1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13360">
        <property type="entry name" value="PH_PLC_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000396">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000049">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037755">
        <property type="entry name" value="Plc1_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="744"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="863"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="68"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="668"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1041"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="693"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1087"/>
            <end position="1101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC51113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1113" mass="123913" checksum="FF333F71AA86F1CC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMG5</accession>
    <name>W6ZMG5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_80116</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682466.1">
        <property type="nucleotide sequence ID" value="XM_007684276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMG5"/>
    <dbReference type="GeneID" id="19125603"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80116"/>
    <dbReference type="eggNOG" id="KOG4372">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027968_1_1_1"/>
    <dbReference type="OrthoDB" id="273452at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000223">
        <property type="entry name" value="Lipase/serine esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF65">
        <property type="entry name" value="ESTERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="3"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC51173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="444" mass="49784" checksum="1DB3CF515650205C" modified="2014-04-16" version="1">MSEKPDHLCVLVHGLWGNPDHLKYVSTTLSERFPSEKLHVLVAARNSGSFTYDGIDTGGERVAQEIEVKLEELAESGHNITKISIIGYSLGGLISRYAIGLLYRRGIFDKIRPINFTTFATPHLGVRTPLKGYHSHLWNVLGARTLSMSGRQLFGVDKFRDTSRPLLGVLADSESIFIQGLAQFKNRSLYANVVNDRTVTYYTAGISSTDPFVDLDKIKINYVDDYDDVIVDREHPVSPREPEEPRAFAQRLTEGTKTVIGRASIVALLSVLVPVGVTAFLINSAFQSVRSHQRIRLHQQGRSGIDYTHYRIPLMINAVRREAENIYGNANHAQSQEYLSNGSEEVASPTQQKTLGEAHKTGSDSEVDSIQAQKEEANLKFPTLALTPEQFKMIDALDNVGFKKHPVHIHNHRHSHAAIIVRMQKEAFNEGKIVIQHWLDNFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMP0</accession>
    <name>W6ZMP0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_33859</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684733.1">
        <property type="nucleotide sequence ID" value="XM_007686543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMP0"/>
    <dbReference type="STRING" id="930090.W6ZMP0"/>
    <dbReference type="GeneID" id="19122423"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33859"/>
    <dbReference type="eggNOG" id="KOG0069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_0_1"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12163">
        <property type="entry name" value="2-Hacid_dh_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="137"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="233"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="373" mass="41191" checksum="C6A086F5367CC4EF" modified="2014-04-16" version="1">MGGGPDIPVRAGASREKELVLCTLPWPEDQASAGTQELKEAFGDVEIKYYHTKYANGKIEPLDVPEEILRRASYLVTLFWLPPDDSSIPSVKLIQFVSAGTNHVANHPIYTDSKIPLCSANGVHGPQIAEWVIMMDLVHSHSYTTLYDNQKKKVWDQRAGMNVSDRVGKRVGILGYGSIGRQVARVAKAMGMDVIAYTASPRKIPESKHDNGYIVPGTGDPDGSIPSAWFSGTEKEHIHEFLKQEIDLLVIAVPLTKDTTHLFSTPEFELLHKSNPKGTYVVNIARGQIIDQKALITALETEQIQGAALDVTDPEPLPEDDPLWDAPNVLITPHCSGASDVYVNRAFQLLIENIKHERSGGQLINEVNRKRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMV9</accession>
    <name>W6ZMV9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UBR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_79598</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682227.1">
        <property type="nucleotide sequence ID" value="XM_007684037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMV9"/>
    <dbReference type="STRING" id="930090.W6ZMV9"/>
    <dbReference type="GeneID" id="19125507"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79598"/>
    <dbReference type="eggNOG" id="KOG2752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025221_1_0_1"/>
    <dbReference type="OrthoDB" id="10262564at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19677">
        <property type="entry name" value="UBR-box_UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040204">
        <property type="entry name" value="UBR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047506">
        <property type="entry name" value="UBR7-like_UBR-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02207">
        <property type="entry name" value="zf-UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
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            <begin position="34"/>
            <end position="112"/>
        </location>
    </feature>
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        <location>
            <begin position="34"/>
            <end position="112"/>
        </location>
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        </location>
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            <end position="393"/>
        </location>
    </feature>
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            <begin position="519"/>
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        </location>
    </feature>
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            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="534"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC51333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="547" mass="58856" checksum="60BE716403C2C418" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP18</accession>
    <name>W6ZP18_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">COCMIDRAFT_85105</name>
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            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="205"/>
        </location>
    </feature>
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            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
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            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="95"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="263" mass="28565" checksum="72D96641450FC1B1" modified="2014-04-16" version="1">MAKALRQTQGGRQRKGSLRKAAMARMRERSSSLRKAAKPSIVTTFDKPLLDSSPADTTAWVPAVQLPSSPAEPTCASRDVLEPPPSPPLLASPISPMAASPAAPYASTTDDDDVMSFYRPLAASSDYSSFAVPSQGPVASLAHRRSTRSNRRTSITALVTPAEIDSDDEWDYSETEWWGWVVLIATWIVFVVGMGSCLGVWSWAWDVGETPYAPPDLEDDATLPITGYYPALIVCTAVTSWVWVVVAWVGMKYFRHAKVGVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPE0</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_84757</name>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="54" mass="6126" checksum="564CF3D5161CEADC" modified="2014-04-16" version="1">MSKRITHYESTLVRNPYTYDDLLPTSKLYGLIGALNEAYFKLIGVGFVHESSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZR37</accession>
    <name>W6ZR37_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">60S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_4773</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC46151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689139.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZR37"/>
    <dbReference type="GeneID" id="19124371"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4773"/>
    <dbReference type="eggNOG" id="KOG1732">
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    </dbReference>
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    <dbReference type="OrthoDB" id="1539250at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3260:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="entry name" value="Ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_eL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018259">
        <property type="entry name" value="Ribosomal_eL21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_eL21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01171">
        <property type="entry name" value="RIBOSOMAL_L21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="116"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="18261" checksum="2EBE26766B8F1416" modified="2014-04-16" version="1">MGHAAGLRAGTRYAFSRDFKKKGMIPLSTYLKQYKVGDIVDVVANGAVQKGMPYKVYHGKTGIVYNVTKSAVGVILQKQVGNRYLEKRINVRIEHVRHSRSREDFLKRVKLNFAKQQKAKETGEPQQMKRQPAMPRGERVVSLKDNKPENITPVPYETYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZS48</accession>
    <name>W6ZS48_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_82473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683220.1">
        <property type="nucleotide sequence ID" value="XM_007685030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZS48"/>
    <dbReference type="STRING" id="930090.W6ZS48"/>
    <dbReference type="GeneID" id="19126061"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82473"/>
    <dbReference type="eggNOG" id="ENOG502SCMA">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071095_0_0_1"/>
    <dbReference type="OrthoDB" id="1894652at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219:SF1">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21203">
        <property type="entry name" value="ECM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890186" evidence="1">
        <location>
            <begin position="17"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="184" mass="19668" checksum="4CD9315E512DF714" modified="2014-04-16" version="1">MLFSRLLLLPLAVASSVTLYVAPVPASEDTAAIASPVPLAQIDYDADQPVGTLVSYTPPTGSYSADRLLRVGLTDPKSNSLHGVVTSAASFSEHYHKKIVIHVDDKGEPFHVGFSTSTKGSGKEIEVEIQRKSTGPKPVLNKPIVLNAEGKLGGEEPEKTFLQKYWWAIALFLLVQLAAGGGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSR6</accession>
    <name>W6ZSR6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_81685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682888.1">
        <property type="nucleotide sequence ID" value="XM_007684698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSR6"/>
    <dbReference type="GeneID" id="19125915"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81685"/>
    <dbReference type="eggNOG" id="ENOG502R9Z7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182433_1_1_1"/>
    <dbReference type="OrthoDB" id="4966402at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="56" mass="6842" checksum="41460A75CAF080B8" modified="2014-04-16" version="1">MCSYNKINFRCGHFEYRIAVYCHFARNDPNHQCFGAWTVKRAWDEPREVCRKCARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUB9</accession>
    <name>W6ZUB9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_24780</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CHS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686151.1">
        <property type="nucleotide sequence ID" value="XM_007687961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUB9"/>
    <dbReference type="STRING" id="930090.W6ZUB9"/>
    <dbReference type="GeneID" id="19120639"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24780"/>
    <dbReference type="eggNOG" id="ENOG502QRVH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050424_1_1_1"/>
    <dbReference type="OrthoDB" id="2189463at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF2">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC47296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="331" mass="36979" checksum="4295465E31AB7022" modified="2014-04-16" version="1">MGFGDFQTICEKAPIPLCAAVGHQDISNGVGIQTRCYARTIEIANTLIFEAANDFMHILALVMTVVMIIHVRSKFTAVGRKEITTFFYIYFLLTIISLVLDAGVTAPGSATYPYFAAAQNGLTSALCTCLLINGFVGFQLYEDGTTLSVWLLRLSSLAMFIVGGAVNLLTFKGWAGLSPMNPIGIFIVTYLVNAICLFIYTVSQIILVIGTLEDRWPLGDILFGIFFFVIGQVILYVFSDTICEGVQHYIDGLFFTTICNLLAVMMVYKYWDSITREDLEFSVGVKQHNWEIKEPYPEDERRGTMYQDSDYTPSLYQQPHGRNSHYSAVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUG8</accession>
    <name>W6ZUG8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_3647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686060.1">
        <property type="nucleotide sequence ID" value="XM_007687870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUG8"/>
    <dbReference type="GeneID" id="19123038"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3647"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_9_1_1"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890031" description="Peptidase A1 domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="42"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="408" mass="43771" checksum="E8C6C6A9BA244C7E" modified="2014-04-16" version="1">MPDSKIVSRALLAALALPALSAELPPGTIAVPMIRDADLAAYYAEFHVGTPPQKEWLKVDTGSPRYSFLDPRNQECVLDATACSTYGTFDNLTSSTCHYEGPGFFDALYASGTGDYLNDTLVLGGVTLPKMYFGYTSQYPFLGRVPKPIGTILGLSLECGGQGPECMDKGPYLLPQLKNASLIDTMATSFYLGPDEFNVTNAQMIIGGAYDKAKVGGDMITLDMVDPFSFVLSSGQTNNVNVTALEVVLDGGNRTSQTFGESGVGVPVLIDTGVASWYVTKTIFGAVSYAFGITDSAPPGKQVVPVDCINRDPNHSKGYISVEFGASGKIDVPLHEIVTLFADGTCGIFMHPREESISIFGDPFMRAVYTIFDQENKTITFARVKHTTEQNIVPFPKGGFKVGSKVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUU4</accession>
    <name>W6ZUU4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_89586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685861.1">
        <property type="nucleotide sequence ID" value="XM_007687671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUU4"/>
    <dbReference type="STRING" id="930090.W6ZUU4"/>
    <dbReference type="GeneID" id="19127508"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89586"/>
    <dbReference type="eggNOG" id="ENOG502QQXX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006632_1_1_1"/>
    <dbReference type="OrthoDB" id="2264294at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="95"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="642"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="654"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="718" mass="80521" checksum="93F85D96EDBD5583" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVK4</accession>
    <name>W6ZVK4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_89191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685703.1">
        <property type="nucleotide sequence ID" value="XM_007687513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZVK4"/>
    <dbReference type="STRING" id="930090.W6ZVK4"/>
    <dbReference type="GeneID" id="19127424"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89191"/>
    <dbReference type="eggNOG" id="ENOG502QQNH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015737_0_0_1"/>
    <dbReference type="OrthoDB" id="5592486at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="36469" checksum="9740065E06F41249" modified="2014-04-16" version="1">MIGICVRATLRSPAPRPLHILAKPTYAYCRQFSSSQLRKEDPRIPGAGREIVDEFAVLREKYDAPKNTIVLAHGLLGFDELRLAGQFIPGIQYWRGITDALAKKGIEVIVAAVPPSGSIENRSAKLAESIALKAKGKQVNIIAGLDSRYMISRLRPTDFKILSLTTIATPHRGSAFADYMFETIGPRQIKRIYKAMEYFGFETGAFSQLTREYMKTSFNPRTPDIPDVKYYSYGASLEPSRWSIFAPSHAIMKPIEGVNDGLVSVESSRWGDYKGTLIGVSHLDLINWTNRLKWFFWELTGSKRNFNAIAFYLDICDMLAKEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVV2</accession>
    <name>W6ZVV2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_88845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685641.1">
        <property type="nucleotide sequence ID" value="XM_007687451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZVV2"/>
    <dbReference type="STRING" id="930090.W6ZVV2"/>
    <dbReference type="GeneID" id="19127355"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88845"/>
    <dbReference type="eggNOG" id="KOG0101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_0_3_1"/>
    <dbReference type="OrthoDB" id="29851at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006452">
        <property type="term" value="P:translational frameshifting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd10232">
        <property type="entry name" value="ASKHA_NBD_HSP70_ScSsz1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000009">
        <property type="entry name" value="Heat shock protein Hsp70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000023">
        <property type="entry name" value="Hsp70 chaperone (BiP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="471"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="471"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="489"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="571" mass="60909" checksum="9B445211F8EEF34F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWM6</accession>
    <name>W6ZWM6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_47701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685233.1">
        <property type="nucleotide sequence ID" value="XM_007687043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWM6"/>
    <dbReference type="GeneID" id="19124369"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_47701"/>
    <dbReference type="eggNOG" id="ENOG502SA3X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1042103_0_0_1"/>
    <dbReference type="OrthoDB" id="443402at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="223" mass="25639" checksum="182EFEF6FCB81E95" modified="2014-04-16" version="1" fragment="single">PNGPLPNDTASAHTNHLWSPGSTKIEQIEICSRMNDQIFLPELKKRYKKHRLMVSRWFSPFRFHHCDFVKFRKVSVDRVFFSCGGLPEDGVFANEYEYDPKPPLGKIPLIELDVFAACLESCDDGCKWSALGPWLHDCFQLPPDTERTTCIPKKRREFDMKSTHDAENLVWGIQPSYALSLFMISIYALVPLLSAFGFWIYWLARHPGDWQNASVPMVTAVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYK0</accession>
    <name>W6ZYK0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_86444</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 19">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="13"/>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684761.1">
        <property type="nucleotide sequence ID" value="XM_007686571.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZYK0"/>
    <dbReference type="GeneID" id="19126856"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86444"/>
    <dbReference type="eggNOG" id="KOG0354">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002513_0_1_1"/>
    <dbReference type="OrthoDB" id="164902at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18033">
        <property type="entry name" value="DEXDc_FANCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12091">
        <property type="entry name" value="FANCM_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18801">
        <property type="entry name" value="SF2_C_FANCM_Hef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000861">
        <property type="entry name" value="Fanconi anemia, complementation group M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1320.20">
        <property type="entry name" value="hef helicase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039686">
        <property type="entry name" value="FANCM/Mph1-like_ID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044749">
        <property type="entry name" value="FANCM_DEXDc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025">
        <property type="entry name" value="FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="FANCONI ANEMIA GROUP M PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="1254"/>
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            <begin position="47"/>
            <end position="62"/>
        </location>
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            <end position="219"/>
        </location>
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        </location>
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            <end position="1095"/>
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            <end position="1125"/>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        </source>
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        </source>
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            <dbReference type="EMBL" id="EUC48741.1"/>
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            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
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    <sequence length="1334" mass="148069" checksum="27E2CE4D158DFCE8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
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    <protein>
        <recommendedName>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
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                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
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                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <text>prephenate + NADP(+) = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH</text>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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    <accession>W7A430</accession>
    <name>W7A430_COCMI</name>
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            <fullName evidence="5">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    </gene>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684575.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W7A430"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_80864"/>
    <dbReference type="eggNOG" id="ENOG502S2S3">
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    </dbReference>
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    <dbReference type="OrthoDB" id="5854584at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039632">
        <property type="entry name" value="TMEM42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="20927" checksum="FC08C3AA1337AA11" modified="2014-04-16" version="1">MSVPKTRSAWLALAVSSGACAAFNGVFAKLTTTTLTASWSSSIAVAFGLSASNKVVEYAIRGLFFGMNLLFNAIMWGLFTRALTLASSTVRVSIINTSANFIITAILSFIIFSESLPALWWLGAAMLVAGSVIIGMREETEKQGVMATTGEAPLLDRDGDANTEGFRDDDEDQDHVELNSVNNGEEESSDEDGVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPE6</accession>
    <name>W6YPE6_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_9026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964113">
        <property type="protein sequence ID" value="EUC41237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPE6"/>
    <dbReference type="GeneID" id="19127649"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9026"/>
    <dbReference type="HOGENOM" id="CLU_1844739_0_0_1"/>
    <dbReference type="OrthoDB" id="6486656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="139" mass="15623" checksum="D017DE4A87A64622" modified="2014-04-16" version="1">MTAIKSPEGCQLLCTIDLVGIANNIYSYDVEQAGGWKSVACNLVEVVLRERGRGVEDAMDVMGKMYRDLFLSLSDDYNDLPTFKDAEQDQVLKEYALGMLDWVKANVEFSLGGQRYFGLEAGSERTRVERMVELLPQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ07</accession>
    <name>W6YQ07_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_61618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964278">
        <property type="protein sequence ID" value="EUC39690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693793.1">
        <property type="nucleotide sequence ID" value="XM_007695603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ07"/>
    <dbReference type="STRING" id="930090.W6YQ07"/>
    <dbReference type="GeneID" id="19124866"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_61618"/>
    <dbReference type="eggNOG" id="ENOG502RNPP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1207286_0_0_1"/>
    <dbReference type="OrthoDB" id="5069333at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="230" mass="25454" checksum="F6D214E2933BEA86" modified="2014-04-16" version="1" fragment="single">LEPVAGTNLGFDMISFPQTSLAEFTTSIPQEDSSAWAFDSIFGPLQHIGEPNEQYKLSFDNLSEGSDSSPTNMDVSISNANEDCLVDRISMSEACFCSTTLLQQLADFVLCCTRCGPRYSSALIICYGIDEISISFGMGTLWGEVSSDRLPIGNAVARDEFNLRFGSYSVKDTDRRALLRVLALKRLNEMQRVIGRLHQIIQQAFIVKSPHHAICADMVSELARNIQARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQJ8</accession>
    <name>W6YQJ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_10079</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964220">
        <property type="protein sequence ID" value="EUC39940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693548.1">
        <property type="nucleotide sequence ID" value="XM_007695358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQJ8"/>
    <dbReference type="GeneID" id="19117746"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10079"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016060_0_0_1"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000614">
        <property type="entry name" value="Zinc finger protein 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="508"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="536"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="566"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="595"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="678"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="688"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC39940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="698" mass="77123" checksum="479F84480A41F1B8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQL5</accession>
    <name>W6YQL5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">54S ribosomal protein L4, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_10188</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964252">
        <property type="protein sequence ID" value="EUC39788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693691.1">
        <property type="nucleotide sequence ID" value="XM_007695501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQL5"/>
    <dbReference type="STRING" id="930090.W6YQL5"/>
    <dbReference type="GeneID" id="19117955"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10188"/>
    <dbReference type="eggNOG" id="KOG3331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063281_1_0_1"/>
    <dbReference type="OrthoDB" id="270763at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038340">
        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010729">
        <property type="entry name" value="Ribosomal_uL29_mit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06984">
        <property type="entry name" value="MRP-L47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="206"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC39788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="255" mass="28917" checksum="678545138E69B321" modified="2014-04-16" version="1">MPTMPSARLLRPGLASTPSDALLAFLAPSAQCAHNGSRACFSTSPQWRKRDNNKIRGVSAVRATALRPRQTLSVRQKDFEKQQLPKPVPIEHKVTGTPDHGLWGFFKDQKLLQTPVDEQRHGRAWTVGELRSRDWDALHQLWWVCVKERNRLATEKIERKRLNAGYGDYENQERDKTVQETMKAILDTLAERHQAYQEAYALAQRDPDIDLSRTDGPQYTQPPYDPLEADDAPYEAQAASASEEAGKDKTIAESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRD0</accession>
    <name>W6YRD0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_109715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964201">
        <property type="protein sequence ID" value="EUC40073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693407.1">
        <property type="nucleotide sequence ID" value="XM_007695217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRD0"/>
    <dbReference type="GeneID" id="19119490"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109715"/>
    <dbReference type="HOGENOM" id="CLU_3068300_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="53" mass="5871" checksum="DB38BF6D1AE24948" modified="2014-04-16" version="1">MACLPCDTTDPRIGCTYALIPNRMYVATVSHQCQTTNRVSRFGRAICEVFSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRR5</accession>
    <name>W6YRR5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7703 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_109138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964176">
        <property type="protein sequence ID" value="EUC40315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693166.1">
        <property type="nucleotide sequence ID" value="XM_007694976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRR5"/>
    <dbReference type="STRING" id="930090.W6YRR5"/>
    <dbReference type="GeneID" id="19119374"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109138"/>
    <dbReference type="eggNOG" id="ENOG502SIDK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045148_0_1_1"/>
    <dbReference type="OrthoDB" id="405906at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056120">
        <property type="entry name" value="DUF7703"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24802">
        <property type="entry name" value="DUF7703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7703" evidence="2">
        <location>
            <begin position="28"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="335" mass="37925" checksum="13B30F276AD06BA9" modified="2014-04-16" version="1">MANVTTPGNGITGANFDIYGANRVLPRAMTAFTAIAWYNSLELLVLIFCIFKKYSGLYFWSLIINALSAWMKQNNVGHNADLYNVLLTVGWILMVPGQSMVLYSRLHLISPNSNLLRIIFWTIILSAICLCVPTVTLNLRQYTTKSPTVYTRGYSIMEKIQMVLFTLQEIFISCVYLCETRKLMLVIFDGKTRKWMWQLVAMNLLLVFLDATLLTMEFLNLYMIQTTFKSLLYSFKLKIEFGVLSQIVRIIQRSSRDATPELGIQTDVEAQKEKKVGVVSEVEVLQHNVPPEWRLSRGATAKVSPIALNAPSRCFLESDASSVASIDLMYPGRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTF5</accession>
    <name>W6YTF5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_107634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964133">
        <property type="protein sequence ID" value="EUC40880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692596.1">
        <property type="nucleotide sequence ID" value="XM_007694406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTF5"/>
    <dbReference type="GeneID" id="19119088"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107634"/>
    <dbReference type="HOGENOM" id="CLU_2928855_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="61" mass="7019" checksum="EFAD97E926520E0E" modified="2014-04-16" version="1" fragment="single">WVAVETLRRVWIADLSGTNKGGKRLFKCCLDILGTPIYHWSFSTHFSTVTIVEFLYNLNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTP4</accession>
    <name>W6YTP4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_107456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964128">
        <property type="protein sequence ID" value="EUC40960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692516.1">
        <property type="nucleotide sequence ID" value="XM_007694326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTP4"/>
    <dbReference type="STRING" id="930090.W6YTP4"/>
    <dbReference type="GeneID" id="19119049"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107456"/>
    <dbReference type="eggNOG" id="KOG0187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112958_0_1_1"/>
    <dbReference type="OrthoDB" id="1727351at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.60.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.20">
        <property type="entry name" value="Ribosomal protein S17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00511">
        <property type="entry name" value="Ribosomal_eS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001210">
        <property type="entry name" value="Ribosomal_eS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018273">
        <property type="entry name" value="Ribosomal_eS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036401">
        <property type="entry name" value="Ribosomal_eS17_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002242">
        <property type="entry name" value="PRK01151.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00833">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116820">
        <property type="entry name" value="Rps17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00712">
        <property type="entry name" value="RIBOSOMAL_S17E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16873" checksum="F63F9F71A8378FB4" modified="2014-04-16" version="1">MGRVRTKTVKKSAKVIIERYYPKLSLDFETNKRICDEIAIIASKRLRNKIAGYTTHLMKRIQRGPVRGISFKLQEEERERKDQYVPEISALDFTQNSESGSLDVDQETKDLLKSMGFDSIPTNVVAVSQQQVVERPRRFNDRPGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUI8</accession>
    <name>W6YUI8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_106799</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin-dependent halogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964115">
        <property type="protein sequence ID" value="EUC41200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692298.1">
        <property type="nucleotide sequence ID" value="XM_007694108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUI8"/>
    <dbReference type="GeneID" id="19118925"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106799"/>
    <dbReference type="eggNOG" id="ENOG502QW6Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024648_4_2_1"/>
    <dbReference type="OrthoDB" id="3340390at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050816">
        <property type="entry name" value="Flavin-dep_Halogenase_NPB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43747:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43747">
        <property type="entry name" value="FAD-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC41200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="545" mass="59554" checksum="3AD940DE0ED2A4EC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUS9</accession>
    <name>W6YUS9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_106484</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="KI964109">
        <property type="protein sequence ID" value="EUC41310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692171.1">
        <property type="nucleotide sequence ID" value="XM_007693981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUS9"/>
    <dbReference type="STRING" id="930090.W6YUS9"/>
    <dbReference type="MEROPS" id="C12.002"/>
    <dbReference type="GeneID" id="19118870"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106484"/>
    <dbReference type="eggNOG" id="KOG1415">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054406_0_2_1"/>
    <dbReference type="OrthoDB" id="427186at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000006">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="10">
        <location>
            <begin position="11"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC41310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="246" mass="27109" checksum="DA0D71D9A4407AF0" modified="2014-04-16" version="1">MAKSTQTYSKHFIPLESSPEIFTELAHNLGLPASLGFQDVLSLDDPELLGMLPRPVYGLILILPTTEAYEKTVEDEDTKLESLQGPKQNDDVVFFRQTINNACGLYAILHAVCNGGVREMIESGSIIAKVLSSSLTNDVDELARALENRQELEKAYADAAIKGDTDAPVNAEDEVDYHYVAFVQSSKSRHLYQLDGDRKRPIDLGTLETDEDALGSKCLDVIRNMVALENNNVNFSLMALVEGAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUX0</accession>
    <name>W6YUX0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_106413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964108">
        <property type="protein sequence ID" value="EUC41345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692156.1">
        <property type="nucleotide sequence ID" value="XM_007693966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUX0"/>
    <dbReference type="GeneID" id="19118858"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106413"/>
    <dbReference type="HOGENOM" id="CLU_031810_0_0_1"/>
    <dbReference type="OrthoDB" id="3798868at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="444" mass="50577" checksum="BFFF662A7C260E3D" modified="2014-04-16" version="1">MVLYEEDGRVVIVHEKYLEEEAEKERGSVREKYPYTDPINVCKQRNGPKSTEDVKIIIESQIFKTLYCEKMFGWGSDFEYIKSFRQREDKILSGSLCRETLILCSSFAKDHFTYNPDSNELRLPVSYPQAKGVNQPDDQLAYIRADEIEAYIFPWLDKVKAYMNSPRSNQTTSQKMKDYLTNPNGPIAMRIPSSLLEKIHLYNCMLQLGLPKFIQSPLIDALIHQLYKTKLSACHLDTIEITICRFYSRGIAILDPVINHLIGTYSLRSLPDRNHPKPAGKRKHKYKDYLPPQTKELAADDVVRLDGTLEIKFENEIVRAVDFSETNRRYLKFTRYEVSRGKLGKDSCLLPPVLPVLGHCIRHWSGVRKNGGTAAAYTGLPLNVGWGKKFAGRGDGVLAEEGDYEVEGGNRLVGWGYFRANGPGLGEEREKEGGPDEDMFSDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVD7</accession>
    <name>W6YVD7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_111489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964417">
        <property type="protein sequence ID" value="EUC39469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007694012.1">
        <property type="nucleotide sequence ID" value="XM_007695822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVD7"/>
    <dbReference type="GeneID" id="19119780"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111489"/>
    <dbReference type="HOGENOM" id="CLU_190102_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="95" mass="10837" checksum="686577A395957CE3" modified="2014-04-16" version="1">MSFEDLEEARAERAEKEKEKEKASAAKGSKKRGRKPKSFAEVPVEEMTEGAGTNLQREDEEANATVRANSMLRLRQPETESLWRAPMYCKNVLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWN7</accession>
    <name>W6YWN7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_31022</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964220">
        <property type="protein sequence ID" value="EUC39939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693547.1">
        <property type="nucleotide sequence ID" value="XM_007695357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWN7"/>
    <dbReference type="GeneID" id="19121789"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31022"/>
    <dbReference type="eggNOG" id="ENOG502ST5U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133420_1_0_1"/>
    <dbReference type="OrthoDB" id="5415072at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031632">
        <property type="entry name" value="SVIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15811">
        <property type="entry name" value="SVIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0519">Myristate</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC39939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="118" mass="12299" checksum="C1D90855EF483893" modified="2014-04-16" version="1">MGNLCGKQSKDNFDGPGRTLGSAPAPTTRASVPSNAAAPKPKVGGPPRTLGDSNKQDDPKAAAAAAAEARANKSASGDLQKKLDAQKRQTNNQTLQQAANENLRAREADQATETRNYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX19</accession>
    <name>W6YX19_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_29251</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964074">
        <property type="protein sequence ID" value="EUC42068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691405.1">
        <property type="nucleotide sequence ID" value="XM_007693215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX19"/>
    <dbReference type="STRING" id="930090.W6YX19"/>
    <dbReference type="GeneID" id="19121470"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29251"/>
    <dbReference type="eggNOG" id="ENOG502QSCH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007574_0_0_1"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF87">
        <property type="entry name" value="COL-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="266"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="654" mass="74042" checksum="D808FCB1F44A648D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX38</accession>
    <name>W6YX38_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_39813</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691383.1">
        <property type="nucleotide sequence ID" value="XM_007693193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX38"/>
    <dbReference type="STRING" id="930090.W6YX38"/>
    <dbReference type="GeneID" id="19123757"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39813"/>
    <dbReference type="eggNOG" id="ENOG502S18R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_3_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="2"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="379"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="449" mass="49676" checksum="A3B0F680857133C7" modified="2014-04-16" version="1">MEIIIVGAGLAGLSTALALSHSLSGTKSKHRILLLESAPQLAEIGAGVQLTPVATRFFLRCGLGPSLLAASAVPSSWHLRRGSDGEVLNRVPMDRFTEWYGGPYIVVHRADLHRILWEELVARREKETAVDVQMRLGTRVVEYGVEEGWVQVQGGERLKADLVIACDGINSSARGQLMRSLGVPQQEWVAGSGMAAYRVMADVTKVRADPLTREIVEEHAGNCWADTNKLVMTYMVRDSDKLNLVLSHPDTDDTSSWTQEQYKAELTRFYGDMDPRVKRLIELASGPVTNWPVHQVLPLPSWTSWAKNFVLIGDAAHAMSFYLSMGVSLAIEDGLVLATALAYHVSRPETFSLASAVTLFETVRKPRAEKISAASQHAGDLLHLGPGPQRDMRDRAARRDGAEGEEETKGDPLLDWTSYGITDKKIRQWVYGHDVLQEVESKKQQMSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYJ0</accession>
    <name>W6YYJ0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Orange domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_7811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964054">
        <property type="protein sequence ID" value="EUC42635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690828.1">
        <property type="nucleotide sequence ID" value="XM_007692638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYJ0"/>
    <dbReference type="GeneID" id="19125399"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7811"/>
    <dbReference type="eggNOG" id="ENOG502RZUI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081019_0_0_1"/>
    <dbReference type="OrthoDB" id="5553410at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.10">
        <property type="entry name" value="PNP-oxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019595">
        <property type="entry name" value="DUF2470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037119">
        <property type="entry name" value="Haem_oxidase_HugZ-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003650">
        <property type="entry name" value="Orange_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37783">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04315)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37783:SF1">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04315)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10615">
        <property type="entry name" value="DUF2470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51054">
        <property type="entry name" value="ORANGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Orange" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="227" mass="26260" checksum="148FBF6C2CAEFD98" modified="2014-04-16" version="1">MATKEATDEATRQRIIKHMNADHHDSIRRYVEAYASRSMFQSRSAKMIDIDLDKMVFSCGSQQAVIGLDPPMTTLREARERMVKMDKDALETLGRSDISITQFVPAYTRPAHLWNFTQCLLAFLLLPRAANWQPGSPIYDYALFMVPSFANFAARYGWLIFMMMLPIHSIEVVIMVMRLAKHGCTFLDGVWWKWVGTCFVEGITSFWRLDALIEEKKRVKEKATKQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYW4</accession>
    <name>W6YYW4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_41005</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase type-X family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="KI964144">
        <property type="protein sequence ID" value="EUC40719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692772.1">
        <property type="nucleotide sequence ID" value="XM_007694582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYW4"/>
    <dbReference type="STRING" id="930090.W6YYW4"/>
    <dbReference type="GeneID" id="19123983"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41005"/>
    <dbReference type="eggNOG" id="KOG2534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008698_4_1_1"/>
    <dbReference type="OrthoDB" id="205514at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.210.10:FF:000005">
        <property type="entry name" value="DNA polymerase IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000010">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.110:FF:000005">
        <property type="entry name" value="DNA polymerase POL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019843">
        <property type="entry name" value="DNA_pol-X_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF29">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY PROTEIN POL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10391">
        <property type="entry name" value="DNA_pol_lambd_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81585">
        <property type="entry name" value="PsbU/PolX domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00522">
        <property type="entry name" value="DNA_POLYMERASE_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase X" evidence="13">
        <location>
            <begin position="337"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="99"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="258"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC40719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="706" mass="79141" checksum="45E9973D55B837EB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z049</accession>
    <name>W6Z049_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_40626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964117">
        <property type="protein sequence ID" value="EUC41149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692328.1">
        <property type="nucleotide sequence ID" value="XM_007694138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z049"/>
    <dbReference type="STRING" id="930090.W6Z049"/>
    <dbReference type="GeneID" id="19123916"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40626"/>
    <dbReference type="eggNOG" id="ENOG502RZJP">
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    <dbReference type="HOGENOM" id="CLU_027207_0_0_1"/>
    <dbReference type="OrthoDB" id="5348546at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
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    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="121"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="523" mass="57674" checksum="39D31BB9B271AC6F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0A1</accession>
    <name>W6Z0A1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_38738</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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            <begin position="26"/>
            <end position="48"/>
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    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="86" mass="10268" checksum="51AED43D0D9FE9CC" modified="2014-04-16" version="1">MALLEKSRDTDYCGRRDYSHILQRRAWGMVGVHVLWLVSMYVRMYVWLSLRMLRRARGCPCACPSRADRPTHGYNAQDSLWMRMKM</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
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                <person name="Salamov A."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
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        <location>
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            <end position="453"/>
        </location>
    </feature>
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        <location>
            <position position="518"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41849.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="518" mass="56080" checksum="0523E5ED1D12CDA8" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3J0</accession>
    <name>W6Z3J0_COCMI</name>
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        <recommendedName>
            <fullName evidence="3 4">Adenylyl cyclase-associated protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="7" type="ORF">COCMIDRAFT_4594</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The N-terminal domain binds to adenylyl cyclase, thereby enabling adenylyl cyclase to be activated by upstream regulatory signals, such as Ras. The C-terminal domain is required for normal cellular morphology and growth control.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CAP family.</text>
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    </dbReference>
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    <dbReference type="eggNOG" id="KOG2675">
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        </source>
    </evidence>
    <sequence length="537" mass="57441" checksum="12A959982F322DA0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3K8</accession>
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        <submittedName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="201" mass="21087" checksum="1D8810D4353D8955" modified="2014-04-16" version="1">MASHDYYGQSQGHGQQGYGQNYEGTSQRQWGSADNNQGYPPQPQAYGQPQHDQYGQANHSPYPPAQSPYPPPSYDSYGQSQNNYGAPPQPVDQYQQGYDPNRSTSPYPPTAHHQQGYQDPSQQYGAPQQQGHHDPQQGYGAPQYGQPGAPGDAAEGDRGLGSALIGGAGGAFVGNKLGGGTLGTLGGAILGAVAANMVPDK</sequence>
</entry>
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        </recommendedName>
    </protein>
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    </gene>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
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        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310:SF10">
        <property type="entry name" value="INOSITOLPHOSPHOTRANSFERASE AUR1_IPT1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Inositolphosphotransferase Aur1/Ipt1" evidence="6">
        <location>
            <begin position="181"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="406" mass="46689" checksum="852636C7CA523287" modified="2014-04-16" version="1">MANSTLPDNGQWNSKPAWKLPGWCEPVMVASILFFAMFITRKRNYKIFAAPSGRNGYLDDAPNDSMDRLLQQSDSDSEFDDVYAAKNPNSPKVRSIGCWKVTTPSTSRFRNNIHSRILQRFPFLIEMFYWVINYAFYRLTAVASAKLFAGRGIWDVSQEHGISVLEAEQFGFLSFLFPVRERDVQQWFMHGHQDALTVLNKCYALIHIPGTVGFICWYYYVAPSFDTFAVARRTLTLTNFCAFMTFVVFPCMPPRLLPAEYGFLDTVRHDDAQSVWMSGKFVNQLAAMPSMHFGYSFCIGMTLIYHSGLFRRTLEPGEVRKNAFWKIFYLVLGIGYPSFILTVIVATANHYFMDALVATCFVFLSFFCNKVFYVFIPLEDLLLYVIRADKPVPTTGDRYRENSGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3M2</accession>
    <name>W6Z3M2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">VanZ-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_4519</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687076.1">
        <property type="nucleotide sequence ID" value="XM_007688886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3M2"/>
    <dbReference type="GeneID" id="19124269"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4519"/>
    <dbReference type="eggNOG" id="ENOG502S56A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096870_0_0_1"/>
    <dbReference type="OrthoDB" id="63581at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037970">
        <property type="entry name" value="vanZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889673" description="VanZ-like domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="22073" checksum="2F6034E8B9D197C7" modified="2014-04-16" version="1">MRIRKPFAGAFVGLIFISAAAGFSPPDYKIPTYKQSDKALHFTAFFLLTLCFYWILETNRRKVVQLTFTVCTLGLGFASEVIQGLLPIHRDFDYYDIVANVLGSLLALGLCNWYHKRMLERKRAARGYTAVAGDEERDIELGENVEGQESGIVRPTVEEELDRWDENAEDWETTEPEAINGRKSLDEDGKKRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3Y8</accession>
    <name>W6Z3Y8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein uS5m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_92840</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687072.1">
        <property type="nucleotide sequence ID" value="XM_007688882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3Y8"/>
    <dbReference type="STRING" id="930090.W6Z3Y8"/>
    <dbReference type="GeneID" id="19128156"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92840"/>
    <dbReference type="eggNOG" id="KOG2646">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037994_1_0_1"/>
    <dbReference type="OrthoDB" id="309483at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000022">
        <property type="entry name" value="28S ribosomal protein S5, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000041">
        <property type="entry name" value="37S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="11">
        <location>
            <begin position="258"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC46472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="422" mass="47516" checksum="665DB8B325A9FF07" modified="2014-04-16" version="1">MSVCRPARCLFTKAASTTLPKPPPQRTFHASASRQARKKRPHYPSIKADELKLLNQAAEAEYPKYDTSETTLLEKKYTPSQIAAIKAAETTIDARDVLTQGQRRTDFWRLNYEDDLAEVDPVTDRPEKLTGDDIEGPKTFRIANEVERDENISRIASENLAKMYPDGIPEDDPGLQNAMDAAITQAALDPRATYTSKNPAALQALGDERHSVIAPDLPRVENRMARQTRRLSTEEEEDPRQKRLLQYLGWDKQKLRSIRVKTLVVHGVTNQTRMGKIRSLYYLTIAGNQDGLLGVGEGKSVEPEEGRKQSVMSAIRNMRPVPRYENRTTFGDLEKKVGATKVQLFSRPPGFGLRVQHLIFELARAAGLQDLSAKTPRSRNKMNVIKATWEALTSQKLPDEIARARGKKLVDVRKVYYGGSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z419</accession>
    <name>W6Z419_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_98024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        </source>
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="20"/>
            <end position="71"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="125"/>
        </location>
    </feature>
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        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="581" mass="65011" checksum="F1CFECC0E27F642C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z434</accession>
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        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_25484</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 10">ATCC 44560</strain>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="protein sequence ID" value="EUC46527.1"/>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_25484"/>
    <dbReference type="eggNOG" id="KOG2615">
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    <dbReference type="HOGENOM" id="CLU_001265_54_5_1"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF6">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08740)-RELATED"/>
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    </dbReference>
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        <property type="entry name" value="MFS"/>
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            <end position="143"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="274"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="326"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="556"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="119"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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            <end position="109"/>
        </location>
    </feature>
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        <location>
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            <end position="21"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
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            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z438</accession>
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            <fullName evidence="5">TOG domain-containing protein</fullName>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
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        </subcellularLocation>
    </comment>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990498">
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="InterPro" id="IPR034085">
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        <property type="entry name" value="XMAP215"/>
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    <dbReference type="InterPro" id="IPR048491">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12609">
        <property type="entry name" value="MICROTUBULE ASSOCIATED PROTEIN XMAP215"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Stu2_CTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21041">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="271"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="227"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="501"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="734"/>
            <end position="855"/>
        </location>
    </feature>
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        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="517"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="540"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="618"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="756"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="795"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC44508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="879" mass="96117" checksum="9794A5DAB943343C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z458</accession>
    <name>W6Z458_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Tetraspanin</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_35781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688698.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z458"/>
    <dbReference type="GeneID" id="19122867"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35781"/>
    <dbReference type="eggNOG" id="ENOG502S3E8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066479_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="24603" checksum="998E51DD4524F79F" modified="2014-04-16" version="1">MPTKLMMTFVGMDLLFAGCGGLLLGFSLISEQSMRASPTVDNVTKNLLLGQCPLTAGVVNAIFVFVTFLLSLPGLFLPNNRGWLRIQGWLVVVCATFTLGLGVAIWVETLETRRNLSALWGRETPLIQSLLQQRFDCCGYVNSTTPPFVQDSTCQNTLVAAQKGGCIGKFSSFANKYLDQIFTAAFGIVGVDVILVLCIAMVLKYRMEQERYRHIDEKNGFGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4A2</accession>
    <name>W6Z4A2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome assembly factor mrt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_5989</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Associates with the pre-60S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4A2"/>
    <dbReference type="STRING" id="930090.W6Z4A2"/>
    <dbReference type="GeneID" id="19124798"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5989"/>
    <dbReference type="eggNOG" id="KOG0816">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071690_0_0_1"/>
    <dbReference type="OrthoDB" id="10262308at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05796">
        <property type="entry name" value="Ribosomal_P0_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000003">
        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033867">
        <property type="entry name" value="Mrt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051742">
        <property type="entry name" value="Ribosome_Assembly_uL10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841:SF1">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 MRTO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="125"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="235" mass="26245" checksum="C1707885FE5F951C" modified="2014-04-16" version="1">MPKSKRAKVVHLTKTDKKGKELSLKLFANVQEAADNFEHIFVFAVENMRNSYLKEVRAEFADSRFFFGKTKVMAKALGQTPAEEHLTNLSQLTEHLNGNVGLLFTNREPSEIIEYFANYSQTDFARAGVVATQTFTVPAGVVYSRGGEVPEEDDVPLPHSMETTIRKWGMPTRLDKGKVILDAPYTIAEEGKPMNSHQTALLKLFGVAMADFKIDLKAYYSKATESVTEVGAMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4D2</accession>
    <name>W6Z4D2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">MAP kinase kinase kinase</fullName>
            <ecNumber evidence="11">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_6114</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Activates the PBS2 MAP kinase kinase by phosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Interacts with by SSK1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="11"/>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688871.1">
        <property type="nucleotide sequence ID" value="XM_007690681.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z4D2"/>
    <dbReference type="GeneID" id="19124846"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6114"/>
    <dbReference type="eggNOG" id="KOG4645">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001999_2_0_1"/>
    <dbReference type="OrthoDB" id="1043025at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038066">
        <property type="term" value="P:p38MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051403">
        <property type="term" value="P:stress-activated MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06626">
        <property type="entry name" value="STKc_MEKK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000482">
        <property type="entry name" value="MAP kinase kinase kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017240">
        <property type="entry name" value="MAPKKK_Ssk2/Ssk22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF32">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037579">
        <property type="entry name" value="MAPKKK_SSK22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="1044"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="72"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="170"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1326"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1329"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="1073"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00065095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR037579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC44608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1350" mass="151796" checksum="61AF88A5C58F7DED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4P0</accession>
    <name>W6Z4P0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">COCMIDRAFT_103126</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(6)-biotinyl-L-lysyl-[protein] + hydrogencarbonate + ATP = N(6)-carboxybiotinyl-L-lysyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11308"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <dbReference type="EMBL" id="KI964056">
        <property type="protein sequence ID" value="EUC42569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690903.1">
        <property type="nucleotide sequence ID" value="XM_007692713.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z4P0"/>
    <dbReference type="GeneID" id="19118229"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103126"/>
    <dbReference type="eggNOG" id="KOG0368">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_5_2_1"/>
    <dbReference type="OrthoDB" id="14612at2759"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.460.10:FF:000001">
        <property type="entry name" value="Acetyl-CoA carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000005">
        <property type="entry name" value="Acetyl-CoA carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000005">
        <property type="entry name" value="Acetyl-CoA carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000005">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000010">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.460.10">
        <property type="entry name" value="Biotin dependent carboxylase carboxyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1770.10">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049076">
        <property type="entry name" value="ACCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049074">
        <property type="entry name" value="ACCA_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013537">
        <property type="entry name" value="AcCoA_COase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
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        </source>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4Z7</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Han J."/>
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</entry>
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                <person name="Schackwitz W."/>
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                <person name="Han J."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
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        </source>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CBS-domain pair"/>
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    </dbReference>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="18307" checksum="56E352E0DF7B686A" modified="2014-04-16" version="1">MAAEPSTASDAPNGDYQALWANKYRGATVEDLDPPPALSVKPTDPISWALMSGLERDYTHLTVIAETNRALLGYISIPHLQQLLKEGKVKDSDPVEEAMHKFQRRGRRYKVITTETPLEELEEFFNGGVDGSGKQEFAVVTDASRKFVLGVATRADLENFAKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7L1</accession>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963973">
        <property type="protein sequence ID" value="EUC46000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687479.1">
        <property type="nucleotide sequence ID" value="XM_007689289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7L1"/>
    <dbReference type="STRING" id="930090.W6Z7L1"/>
    <dbReference type="GeneID" id="19128372"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94025"/>
    <dbReference type="eggNOG" id="KOG0829">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080773_1_1_1"/>
    <dbReference type="OrthoDB" id="1294322at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL20" evidence="5">
        <location>
            <begin position="22"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="190" mass="22436" checksum="DA84D1B8F2FA465D" modified="2014-04-16" version="1">MRLLGFSRPHLNRPSTTDLRCEYQIIGRHLPSEANPAPKIYRMRIFAPNEVVAKSRFWYFLGKLRKIKKANGEIVSVNQIHEKKPQKVKNFGIWIKYDSRSGTHNMYKEYREMSRVAAVEALYQDMAARHRTRFRSVQILKVVEVEKADDLRRPYIKQLLTKNLKFPLPHRINKKAGKKVFAAHRPSTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7Q3</accession>
    <name>W6Z7Q3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA N(6)-methyladenine demethylase</fullName>
            <ecNumber evidence="2">1.14.11.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_100394</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an N(6)-methyladenosine in mRNA + 2-oxoglutarate + O2 = an adenosine in mRNA + formaldehyde + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:49520"/>
            <dbReference type="Rhea" id="RHEA-COMP:12414"/>
            <dbReference type="Rhea" id="RHEA-COMP:12417"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="1.14.11.53"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:49521"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="9">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.53" evidence="2"/>
    <dbReference type="EMBL" id="KI964024">
        <property type="protein sequence ID" value="EUC43609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689892.1">
        <property type="nucleotide sequence ID" value="XM_007691702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7Q3"/>
    <dbReference type="STRING" id="930090.W6Z7Q3"/>
    <dbReference type="GeneID" id="19117666"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100394"/>
    <dbReference type="eggNOG" id="KOG2731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029471_0_0_1"/>
    <dbReference type="OrthoDB" id="6614653at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990931">
        <property type="term" value="F:mRNA N6-methyladenosine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.590:FF:000014">
        <property type="entry name" value="Oxidoreductase, 2OG-Fe(II) oxygenase family family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004574">
        <property type="entry name" value="Alkb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557:SF3">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Alpha-ketoglutarate-dependent dioxygenase AlkB-like" evidence="11">
        <location>
            <begin position="180"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604574-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC43609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="366" mass="41301" checksum="012DD3B9D2832DC6" modified="2014-04-16" version="1">MDLSMDATERKGSVQHDTHATPPQFIQKEHWRYQSMRKADLENDPDIFDLSKRNQFSEDWKDIWRPAGAIPAAQIEAACMAYAGGEPLSAPVQDAQIFEHRDFPGLQVVSQLLPPETQVLFTSCLMHRDLADPGHKINLQADFDIPYPPKPTSEPSRFDSNFFLRDRAAEPDCLIPKSPDKQKPLNNEQFLYSKLRWLTLGEQYDWPTRSYAKHATPFPEDLSRLVTGLFPHIRPESGVVLMYSAKDFMPVHRDVSEQCQRALASFSVGCDGIFIMAKGEDGGQGENAPRSVAIRVHSGDVVHLTGDARWAWHAMARCIPSTCPPHLASWPVGTPGATPAEEKAYKKWKGYMSTKRINVSCRQVWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z890</accession>
    <name>W6Z890_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycogen [starch] synthase</fullName>
            <ecNumber evidence="8">2.4.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_93452</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18549"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.11"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:18550"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 3 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.11" evidence="8"/>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687305.1">
        <property type="nucleotide sequence ID" value="XM_007689115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z890"/>
    <dbReference type="STRING" id="930090.W6Z890"/>
    <dbReference type="GeneID" id="19128272"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93452"/>
    <dbReference type="eggNOG" id="KOG3742">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015910_1_0_1"/>
    <dbReference type="OrthoDB" id="6335297at2759"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03793">
        <property type="entry name" value="GT3_GSY2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000014">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000045">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008631">
        <property type="entry name" value="Glycogen_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176:SF3">
        <property type="entry name" value="GLYCOGEN [STARCH] SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176">
        <property type="entry name" value="GLYCOGEN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05693">
        <property type="entry name" value="Glycogen_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="615"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="680"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="686"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC46175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="704" mass="79761" checksum="BAA1AB754F3649D5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8F3</accession>
    <name>W6Z8F3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_99829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689649.1">
        <property type="nucleotide sequence ID" value="XM_007691459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8F3"/>
    <dbReference type="STRING" id="930090.W6Z8F3"/>
    <dbReference type="GeneID" id="19129545"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99829"/>
    <dbReference type="eggNOG" id="KOG1674">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018149_3_1_1"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
        <property type="entry name" value="PHO85 CYCLIN-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="74"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="358" mass="40186" checksum="763EB51D42619FDD" modified="2014-04-16" version="1">MPYSPNLAAENQAALDHFIQLPVSSDMISYLAQKATQVIRCEPCVNKTLPPTPPASPSQHIASHPREPALPSVEEFITSIVERSHVQTATLMSSLIYLSRLRSRLPPVAKGMRCTVHRIFLASLILAAKNLNDSSPKNKHWAKYSSVRGYDNFGFSITEVNLMEKQLLFLLDWDLRINTDDLYYHFEPFLAPIRVWQSRQAEKARLAEKEKELARKQYQLTTENLSRSVHTYPSNSSMSSHTSRAQRHRMQYVPSSRAPSRTPSLSPPTRSSSASVSSESPSSFHEEPSEAVLHRYDADQGANVVYINGPIPYTASKQQHALPLYEHQPSKKVKTSAGGIFSRMFGQTGAYAGRQVTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8X1</accession>
    <name>W6Z8X1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_4716</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687271.1">
        <property type="nucleotide sequence ID" value="XM_007689081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8X1"/>
    <dbReference type="STRING" id="930090.W6Z8X1"/>
    <dbReference type="GeneID" id="19124349"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4716"/>
    <dbReference type="eggNOG" id="KOG0183">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_4_0_1"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042175">
        <property type="term" value="C:nuclear outer membrane-endoplasmic reticulum membrane network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03755">
        <property type="entry name" value="proteasome_alpha_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000004">
        <property type="entry name" value="Proteasome subunit alpha type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="273" mass="29659" checksum="074E75FCDF49AE3E" modified="2014-04-16" version="1">MASGYDRALSVFSPDGHVFQVEYALEAVKRGTCAVGVKGSDIVVLGCEKRSAMKLQDTRITPSKICLVDTHVALAFAGLNADARILVDKARLEAQSHRLTVEDPVSIEYITKYVAGVQQRYTQSGGVRPFGISTLIVGFDPNDKTPRLYQTEPSGIYSAWKANAIGRSSKTVREFLERNHKEGMDREETIKLTVKSLLEVVQTGAKNIEIAIMAPGKPIEMLPVEDIEKYVDNINTEKQEEAANRRPGRQPGTGQAAILTRQTPGEGSGAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z961</accession>
    <name>W6Z961_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_87935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685261.1">
        <property type="nucleotide sequence ID" value="XM_007687071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z961"/>
    <dbReference type="STRING" id="930090.W6Z961"/>
    <dbReference type="GeneID" id="19127163"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87935"/>
    <dbReference type="eggNOG" id="ENOG502RAK8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1082088_0_0_1"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052276">
        <property type="entry name" value="Diphthamide-biosynth_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44240">
        <property type="entry name" value="DNAJ DOMAIN (PROKARYOTIC HEAT SHOCK PROTEIN)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44240:SF10">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="98"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="269" mass="30235" checksum="08C2495F1ED551FE" modified="2014-04-16" version="1">MSPSPLPSDQVWKSSFSPFRSPSPAKRFAHERNQSEAVQRPRPMSISSNSPAVQHSKRASIYVSDASVILAQRTPMASPISSPDSTYDPALESPDAVDHYAILEITPKATTDEVKAAYRRLRVVYFSSDAKKYRALQAAFDTLMNPETREVYDANYQPHPAAPTSLASIGEILDPGKHWRQDSAHGDDSAIAEEEEEEEQLQQLQEEPEEQEEVRNDDPNWGLKHYNPRFEPVLGTEPYMSYIPLPTNLLLFCRGPTYVGNFAFNARPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z967</accession>
    <name>W6Z967_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689345.1">
        <property type="nucleotide sequence ID" value="XM_007691155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z967"/>
    <dbReference type="GeneID" id="19124982"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6515"/>
    <dbReference type="eggNOG" id="ENOG502S62I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100997_3_2_1"/>
    <dbReference type="OrthoDB" id="2820488at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886772" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19512" checksum="A9B0A2FAC2EB3704" modified="2014-04-16" version="1">MRFTFLASTIVTSVSVLAAPTGLHSRTDVLVEPRAALAKPAPCVRDPSATEMQNKARFNTFVQALIYKPDITEAFSYVAQDYVNHGIPLLNGFDTGWDVFSLTWDLSSITPLGSTFQYPQGWVKYKKQFREVVERFRMDGGCIVEHWVQNEEVPLNAMTVKRSHSNPITHCCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9M3</accession>
    <name>W6Z9M3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Agmatinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_41255</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964168">
        <property type="protein sequence ID" value="EUC40401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693073.1">
        <property type="nucleotide sequence ID" value="XM_007694883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9M3"/>
    <dbReference type="STRING" id="930090.W6Z9M3"/>
    <dbReference type="GeneID" id="19124024"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41255"/>
    <dbReference type="eggNOG" id="KOG2964">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_1_1_1"/>
    <dbReference type="OrthoDB" id="288726at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033389">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via agmatine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF26">
        <property type="entry name" value="GUANIDINO ACID HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
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    </dbReference>
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    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="35620" checksum="395259AE83E60FD1" modified="2014-04-16" version="1">MRLNSWTGLLPTVAALDVGPDYSHPIEGLYPSWLCKEKKGRSYNTVWEVNPFEEGLAIVDCGDVPFTPFDAAHVVKRVEQGYRQVLYHPTSSANSWEHPRIISLGGDNSITLPILRSLKTVYGSISVIHLDSHLDTWDPYQGYTGIRSNQSALTHGTFFWHASRKGCISKRTSVHGSLRTKPFASALTLHPKDYEIERDVGFGIIEAHEIDDIDMNGIIAKTLNFVKDTPAYLSIDIDVLDPSIAPATGTPEFGGWTTRELKRFIRGLEGINLFGVDVVEVSPPYDTAAKITSIAAADLIVDIMAAMAKSNKGPALLRVKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9T0</accession>
    <name>W6Z9T0_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_25495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9T0"/>
    <dbReference type="GeneID" id="19120771"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25495"/>
    <dbReference type="HOGENOM" id="CLU_1695168_0_0_1"/>
    <dbReference type="OrthoDB" id="432483at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="155" mass="17181" checksum="C7A614F642C76A16" modified="2014-04-16" version="1">MVFDCAGNQCEHARLSNPAFTLDTISEKAKQLGRHEKDIGQNIAVTKCVETKIQEEIRQLNTASDLKSNNAERAQQKSFSDLVDDESNDATKELTTEQQLLKSSDQTYYQLSKEALRKTMSQCTGTNVSIRGVTVTEQGLTINGVIPETGKELKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9U7</accession>
    <name>W6Z9U7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_35627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9U7"/>
    <dbReference type="GeneID" id="19122827"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35627"/>
    <dbReference type="eggNOG" id="ENOG502SJFX">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_3_1"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF10">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="271"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="2">
        <location>
            <begin position="546"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="846" mass="95025" checksum="8B4BFC16E7D3CEBD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAV0</accession>
    <name>W6ZAV0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_25013</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686406.1">
        <property type="nucleotide sequence ID" value="XM_007688216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAV0"/>
    <dbReference type="STRING" id="930090.W6ZAV0"/>
    <dbReference type="GeneID" id="19120688"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25013"/>
    <dbReference type="eggNOG" id="KOG0955">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002663_0_0_1"/>
    <dbReference type="OrthoDB" id="20839at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15492">
        <property type="entry name" value="PHD_BRPF_JADE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000007">
        <property type="entry name" value="Bromodomain containing 1, isoform CRA_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="394"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="453"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="175"/>
            <end position="233"/>
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            <end position="392"/>
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            <end position="643"/>
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            <end position="1085"/>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS51805"/>
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            <dbReference type="EMBL" id="EUC47100.1"/>
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            <dbReference type="Proteomes" id="UP000054032"/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
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            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fung_rhodopsin"/>
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    </dbReference>
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        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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    </feature>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="387" mass="42961" checksum="5553C1C73827A751" modified="2014-04-16" version="1">MAPIIDPQESLMAFRQRLDGVAIFTYILIMLLVPLKIWCRYRHRGWRNVQWDDYMSIVALALANGFFYVCIIGMRDSLGLHIYEIENPLQIIAFLKNIYVGNILYTLCITSVKLSVLAFYWRLFEIKARITIYIVTAAAIAWCTSILLCVIFNCIPVQAAWDVTITGAKCISIRAIYLGGSVPNVCLDLVIVLMPLPHVWRLHAPLAQRIVLAGMFALGTFIAVVSLVRLIIFLQIPIATQGDVTYNFREIIVWSIVEVNIGLACACLPSLKPVFQAVGLSKLFSFSSSRPSDVESQGPAHQFASGGSSGSRPRKKGATGGLFSTLAGISRMDDEEETKFVTEDLGKNNVDIELARVSEDSEQRNAAGGINVQKNWSVLVDERKPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC50</accession>
    <name>W6ZC50_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_35068</name>
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    <organism evidence="2 3">
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686083.1">
        <property type="nucleotide sequence ID" value="XM_007687893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC50"/>
    <dbReference type="GeneID" id="19122702"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35068"/>
    <dbReference type="eggNOG" id="ENOG502QR1X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078562_0_0_1"/>
    <dbReference type="OrthoDB" id="4311043at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="283" mass="31245" checksum="4FE60798EFEDDEF1" modified="2014-04-16" version="1">MEDVATLEFFARDVIDLDYIVISHAHFDHLPGADRLALKTSATVIADCEAINFAGGERVPLFTKDILTKASENSIEFAPSPPLALPKPHVKFASLAVHVWPSLHSLMLRVSPHDIPEVFDTNKSDQGGGDGYACSLDITQLIWYGLFRLEAFIPEDHMDAGTSAFSDYIQDRKKNIMSPCDGGKFMCNFIIGVKIPKPDVAILGAGGRANLNGRPFVGSAAEFLKLQTQWLHEPPQILFCLHDESIIKPYKTDVIAAKEVIEQHTRSKVLGTELATPYVLFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCH0</accession>
    <name>W6ZCH0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_90064</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686043.1">
        <property type="nucleotide sequence ID" value="XM_007687853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCH0"/>
    <dbReference type="GeneID" id="19127604"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90064"/>
    <dbReference type="eggNOG" id="ENOG502QQA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021993_0_0_1"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="39"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="437" mass="46666" checksum="C14EBD60DEBB15F7" modified="2014-04-16" version="1">MSHPSGSNEASPLLGDNRRTSVTPDQGPSQEDPETMNARLIFKIAAAMYSFATLGLFNSSIGAVLPLLSQHYNLSDIQVSSIFLAGPVGYVFAAQFSDAVHYRFGQRGIAFAGPILQVLATATVAAHPGFGLILVAFAFQGLGTGLLDGSWCAWAGSMKKANTISGLLHGSFSVGAALGPLLLTMLTAKHRHWWTWYSILAGACALSFIVQVAAFRHESASVYRQSKQSKISDSRIDLREIFKHPATWLCAAFFLTYVGVETSISGWVVSFMLRERHASDYIAGLSSSGYWIGMAIGRLVLGFATDRMGVRPATTLYFLFAIVFEALFAAFSSLEASVIFMTATGFVHGPLFPSGVVVLTRLLPAELHVAAVSFVASLGQIGGAVLPFAIGAVVQGLGIGVFRFAIVVETLLALLLWLAFARLRPALLPISAAHTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD13</accession>
    <name>W6ZD13_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_36906</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM234 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963986">
        <property type="protein sequence ID" value="EUC45329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688131.1">
        <property type="nucleotide sequence ID" value="XM_007689941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD13"/>
    <dbReference type="GeneID" id="19123136"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36906"/>
    <dbReference type="eggNOG" id="ENOG502SCJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108086_3_0_1"/>
    <dbReference type="OrthoDB" id="43458at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018908">
        <property type="entry name" value="TMEM234"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10639">
        <property type="entry name" value="TMEM234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC45329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="16877" checksum="47A8E86157CD3204" modified="2014-04-16" version="1">MDPDEPIANEPQPSIFRWILGFLMVGACWGLTTPFMRKAAMNYTPPQRPTLTDPNNSWLKKKVLGVFYAVIGVLSRPAYAIPLLLNVTGSVWFFILIGKAELSLTVPITNSLAFLFTVLGEWWAEKKVISRDTWIGMAFVLGGIGLCVQSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDI2</accession>
    <name>W6ZDI2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cornichon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_3025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cornichon family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685385.1">
        <property type="nucleotide sequence ID" value="XM_007687195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDI2"/>
    <dbReference type="STRING" id="930090.W6ZDI2"/>
    <dbReference type="GeneID" id="19121648"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3025"/>
    <dbReference type="eggNOG" id="KOG2729">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112942_0_0_1"/>
    <dbReference type="OrthoDB" id="434393at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003377">
        <property type="entry name" value="Cornichon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033466">
        <property type="entry name" value="Cornichon_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03311">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01398">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01340">
        <property type="entry name" value="CORNICHON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="16273" checksum="738286D46B39A04E" modified="2014-04-16" version="1">MTGEAWLYLLAVLINAVNLFLQVFFTIMYSDLECDYINPIDLCNRLNTYIIPEAAVHAFLTFLFLINGYWMALVLNLPLLAWNAKKIFENQHLLDATEIFRKLNVHKKESFIKLGFHLLMFFFYLYSMIVALIRDESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDU0</accession>
    <name>W6ZDU0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">L-cystine transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_34472</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cystine(out) + H(+)(out) = L-cystine(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:66172"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:35491"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:66173"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cystinosin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685412.1">
        <property type="nucleotide sequence ID" value="XM_007687222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDU0"/>
    <dbReference type="GeneID" id="19122565"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34472"/>
    <dbReference type="eggNOG" id="KOG3145">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046327_0_1_1"/>
    <dbReference type="OrthoDB" id="75720at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015184">
        <property type="term" value="F:L-cystine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000016">
        <property type="entry name" value="Cystinosin homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005282">
        <property type="entry name" value="LC_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00951">
        <property type="entry name" value="2A43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131:SF5">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0458">Lysosome</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0769">Symport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC48078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="31937" checksum="803FC67B441C67CC" modified="2014-04-16" version="1">MNPELEAFARAISRVLGWAYFLAWSLSFYPQPISNYVRKSTLGLAIDFPTLNVLGFTCYTISTASFLYSPTIKAQYAQRHPEAPVTTVRFNDFLFAAHGAVMCFIIYSQFFEPIWGFEVGKRQRVSRVVFTVWWACVAVIFAVVLLVRFKGQNGGYNADGWAWIDVIYTLGYVKLLTVFLKYIPQAWVNYKRKSTVGWSIYPMLLDFAGGWLSLAQLCIDSALENDWSGVTGNPVKFGLGNITIVFDVIFMVQHYVLYRHASEKRVEDEEESEALVGAMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE30</accession>
    <name>W6ZE30_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Only prolin and serin are matching in the corresponding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_1296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683378.1">
        <property type="nucleotide sequence ID" value="XM_007685188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE30"/>
    <dbReference type="GeneID" id="19119834"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1296"/>
    <dbReference type="eggNOG" id="ENOG502SJFJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020684_1_0_1"/>
    <dbReference type="OrthoDB" id="3882058at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="57462" checksum="F167DB025523CB2E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEX9</accession>
    <name>W6ZEX9_COCMI</name>
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        <recommendedName>
            <fullName evidence="5 12">Vacuolar protein sorting-associated protein 27</fullName>
        </recommendedName>
    </protein>
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        <name evidence="17" type="ORF">COCMIDRAFT_2639</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Endosome membrane</location>
            <topology evidence="2 12">Peripheral membrane protein</topology>
            <orientation evidence="2 12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the VPS27 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC48575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686719.1"/>
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    <dbReference type="STRING" id="930090.W6ZEX9"/>
    <dbReference type="GeneID" id="19120923"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2639"/>
    <dbReference type="eggNOG" id="KOG1818">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011862_1_0_1"/>
    <dbReference type="OrthoDB" id="957735at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="FYVE_spVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21385">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16979">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000031">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR017073">
        <property type="entry name" value="HGS/VPS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR049425">
        <property type="entry name" value="Vps27_GAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21356">
        <property type="entry name" value="Vps27_GAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036956">
        <property type="entry name" value="Hrs_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0967">Endosome</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VHS" evidence="16">
        <location>
            <begin position="26"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="15">
        <location>
            <begin position="168"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="280"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="477"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="335"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="461"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="542"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="585"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="632"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="669"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC48575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="754" mass="83557" checksum="4DFFB1061103D85E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFC2</accession>
    <name>W6ZFC2_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_4697</name>
    </gene>
    <organism evidence="4 5">
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
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    </reference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
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        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="213"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="380" mass="42627" checksum="69497B1D08CB9D52" modified="2014-04-16" version="1">MCPEPSESDRITYEEARNGAAAYLQSRLSAKNEEADKDFEIPVINLEPSFSDSLSDRQKVADQIRKACTTSGFFYITNHRIPKSACDGILHQAKRFMKELPLEKKEELHLKHNKFGLGWEPSEYTSIAGDKEEKEVFNFAYEADLDPTGGDGQYKNLDGSTGNANMWPKEEDLPGFYREVKEYYGNVLSLARHLFRLFALSLSLPESHFDPLTTHPGGIARLLYYPPPSSPLPSSSSSSPSSDETSQIGLGAHSDYECFTLLLPSFVPGLEILKPSGTWYIAPHFPNTLIVNVADFLMRWTNGMYKSTVHRVVNRGTEERYSVPFFFSVNYDVVVETLPGCKKEGEGEGEWKPVRAGEYILERLRSTVGYGKGFEVGKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFG9</accession>
    <name>W6ZFG9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_86366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684767.1">
        <property type="nucleotide sequence ID" value="XM_007686577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFG9"/>
    <dbReference type="STRING" id="930090.W6ZFG9"/>
    <dbReference type="GeneID" id="19126842"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86366"/>
    <dbReference type="eggNOG" id="ENOG502S22Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035244_1_0_1"/>
    <dbReference type="OrthoDB" id="10039566at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="354" mass="38381" checksum="982C65B4D9E94E76" modified="2014-04-16" version="1">MDDKGGTTRTDGVYTTPQKRSGVMNKLYPPGEKPGVKGRMKNHCRKFWWCDLLVFAIIVLIIVLPIIYVAIPKRAQREINASTIEVLSQEVTNPTPDGIHLKLDTVIRSDSSYHPKIDGFRGALSIAGQTPFLYIDIPQVKSEAETPVTVDQELKLANKDAFSNYTKLVLGSEEFSIHLDGKTNIHLGGLPTMDVNYNKIVTMKGLNRLAGLNITDVSILSGDKILADNSNLIAQVSIPNPSVMTLDLGNVTMNLGVDGKSIGYCLIPNVLLKPGANTFPLQSRVDQLSILGLIQSKYNNAVLPLQISGNSSVRNGEHLVYYEDAIKSNTINLNLNVGPALAAVGINVTSFGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFL4</accession>
    <name>W6ZFL4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_29088</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964067">
        <property type="protein sequence ID" value="EUC42276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691209.1">
        <property type="nucleotide sequence ID" value="XM_007693019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFL4"/>
    <dbReference type="GeneID" id="19121437"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29088"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019225_1_0_1"/>
    <dbReference type="OrthoDB" id="2915840at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13738">
        <property type="entry name" value="Pyr_redox_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC42276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="568" mass="63533" checksum="BFE3FD459251BA5F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFN6</accession>
    <name>W6ZFN6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_29064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964066">
        <property type="protein sequence ID" value="EUC42306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691174.1">
        <property type="nucleotide sequence ID" value="XM_007692984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFN6"/>
    <dbReference type="STRING" id="930090.W6ZFN6"/>
    <dbReference type="GeneID" id="19121430"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29064"/>
    <dbReference type="eggNOG" id="KOG3923">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034311_1_0_1"/>
    <dbReference type="OrthoDB" id="409956at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF16">
        <property type="entry name" value="D-AMINO ACID OXIDASE (AFU_ORTHOLOGUE AFUA_5G11290)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="364" mass="39423" checksum="BC3C20E080FCD3C4" modified="2014-04-16" version="1">MSTKNVVVAGAGVIGLSAALVLSRHKNLSITVVAKHMPGDYDIEYASPWAGANYFPVGKPGSILQKFERATWPELERLCRQVPEAGIHFQNTRVYGRKKDAGTATGQWFEELTKEDAWFKDVVPNFRVLPKSELPEDCDTGTEFSSVCINTAVYLPWILGQCVKAGVIIKRGILSHISEAASFHPSGHADVIVNCTGLLASKLGGVMDSNVYPGRGQIVLVRNEPGVMLTVSGTDDGSEEATYIMQRAVGGGTILGGCLQHGSWESQPDPNLAQRIMQRSIDLCPALAPKTGKVTELDIVRHGVGLRPMRTGGPRVEKEVIDGKWVVHSYGHAGYGYQSGWGSAWEAEQLVLSIVQDDKTKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFW5</accession>
    <name>W6ZFW5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_85912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684539.1">
        <property type="nucleotide sequence ID" value="XM_007686349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFW5"/>
    <dbReference type="GeneID" id="19126763"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85912"/>
    <dbReference type="HOGENOM" id="CLU_1959190_0_0_1"/>
    <dbReference type="OrthoDB" id="3798501at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="128" mass="14446" checksum="F37DE222247735CD" modified="2014-04-16" version="1">MEIHQIRNRRPFLDQEGPPVPPKPYASNAPSTTHDRLTHDRLATVTSSRDATSKPLPPVPGSRLSRGARSKVESKPLPKPPKSSILQSTFLWILGFAVWFLLIVILLPVVTEKDAMPGFNRWLRNRFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG47</accession>
    <name>W6ZG47_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">1,3,6,8-tetra-HN reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_86046</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684661.1">
        <property type="nucleotide sequence ID" value="XM_007686471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG47"/>
    <dbReference type="STRING" id="930090.W6ZG47"/>
    <dbReference type="GeneID" id="19126791"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86046"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="28473" checksum="DBCCDE649779CF67" modified="2014-04-16" version="1">MVVTVPTASLEGQVALITGAGRGIGRGCAIELGKRGASVVVNYVSSEGPANEVCEIIRGFNNGAKAVAIKADVSKVSEIHRLFEEAKQAFGKINIVMSNSGTESWDKTEEISEEKYDHVFNLNTRAQFFVGQTAYKYIEDNGRIILMSSIAAGLLGVKDHALYNASKMAVIGFIKAFATDFGKRGVTVNGVAPGGIKSDMFTQNAWHYIPGGTPEWPAEKIESLMASHCPLGRCAVPEDVARVVAFLASEDGGWVNGQVLTISGGSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGQ9</accession>
    <name>W6ZGQ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrodipicolinate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_23190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684295.1">
        <property type="nucleotide sequence ID" value="XM_007686105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGQ9"/>
    <dbReference type="STRING" id="930090.W6ZGQ9"/>
    <dbReference type="GeneID" id="19120388"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23190"/>
    <dbReference type="eggNOG" id="ENOG502SG3E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_0_2_1"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF47">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="35511" checksum="2FDD1E48129320B2" modified="2014-04-16" version="1">MPISKSTIDEKKIMLPPGVYTPVISLYKPTKTQEIDLEAMYKHCQYLVRAGQHGLVYQGTNGEAVLLSRSEKISILQTARRAVTDLGFPNYPLVAGISGQSTNESIELAQDARDAGASFGLLLPPSFWAKSLTEDALLGFYRDVADASSLPIVIYNFPAVTSGVDLNSDDLAALAQHPNIVAVKLTCGNVGKAIRLTSRFSPAQFSVYGGSSDFLFPTLEGGGVGCVTGMGNVFPKSTARVYDLWMEGKKEEARALQNVVANAEWACKKSLALTKFAAGHFLGSKLGIKSEAFWPRRPYLPPGEKIREWTVDVMGVLEAEENSIEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGU9</accession>
    <name>W6ZGU9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_33394</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684298.1">
        <property type="nucleotide sequence ID" value="XM_007686108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGU9"/>
    <dbReference type="GeneID" id="19122315"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33394"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF29">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="37"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC49128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="520" mass="58439" checksum="C91E7E5F2D35E2A4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHU6</accession>
    <name>W6ZHU6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Long chronological lifespan protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_91304</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LCL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC46984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686501.1">
        <property type="nucleotide sequence ID" value="XM_007688311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHU6"/>
    <dbReference type="STRING" id="930090.W6ZHU6"/>
    <dbReference type="GeneID" id="19127858"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91304"/>
    <dbReference type="eggNOG" id="ENOG502S416">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142363_0_0_1"/>
    <dbReference type="OrthoDB" id="2234316at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23996">
        <property type="entry name" value="LCL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034543">
        <property type="entry name" value="LCL2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38425">
        <property type="entry name" value="LONG CHRONOLOGICAL LIFESPAN PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38425:SF1">
        <property type="entry name" value="LONG CHRONOLOGICAL LIFESPAN PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887510" description="Long chronological lifespan protein 2" evidence="5">
        <location>
            <begin position="21"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="129" mass="14095" checksum="01737E09C5DA5D3A" modified="2014-04-16" version="1">MPRLNAIILLLFSLAYPITAQFGFFDQMFGGGNHHGGHNHGGGHNHGEAQNVRSDSSWYQAQYEGAQCSHYLCPGTLSCVHFPHHCPCAWENVEDKVELGDGIAICGSKGGWKEGEFAKKVELARKGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHW2</accession>
    <name>W6ZHW2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_1625</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683831.1">
        <property type="nucleotide sequence ID" value="XM_007685641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHW2"/>
    <dbReference type="STRING" id="930090.W6ZHW2"/>
    <dbReference type="GeneID" id="19119908"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1625"/>
    <dbReference type="eggNOG" id="KOG1039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018150_1_0_1"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045072">
        <property type="entry name" value="MKRN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224:SF10">
        <property type="entry name" value="IP09428P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224">
        <property type="entry name" value="MAKORIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="301"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="408"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="476"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="539"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="555"/>
            <end position="567"/>
        </location>
    </feature>
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        <location>
            <begin position="588"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="606"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="642"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="659" mass="70400" checksum="A9C198855638E997" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIB4</accession>
    <name>W6ZIB4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2-oxoisovalerate dehydrogenase subunit alpha</fullName>
            <ecNumber evidence="9">1.2.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_38780</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the BCKDHA family.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="9"/>
    <dbReference type="EMBL" id="KI964035">
        <property type="protein sequence ID" value="EUC43246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690223.1">
        <property type="nucleotide sequence ID" value="XM_007692033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIB4"/>
    <dbReference type="STRING" id="930090.W6ZIB4"/>
    <dbReference type="GeneID" id="19123546"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38780"/>
    <dbReference type="eggNOG" id="KOG1182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_1_2_1"/>
    <dbReference type="OrthoDB" id="3845at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:branched-chain 2-oxo acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02000">
        <property type="entry name" value="TPP_E1_PDC_ADC_BCADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000015">
        <property type="entry name" value="2-oxoisovalerate dehydrogenase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050771">
        <property type="entry name" value="Alpha-ketoacid_DH_E1_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="10">
        <location>
            <begin position="105"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC43246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="463" mass="52091" checksum="BE01AAD6148E62C4" modified="2014-04-16" version="1">MSFRYISRRLQLQRLLSLSARPSNASIRPTGPPWQTTCRGVASTPTAERVLFPGALNSEFTNTMEFMHPSKTKAISTYRVMDQYGEIINKEVGVETSDEEALSLYKNMVKLSIMDLLMFEAQRQGRLSFYMVSAGEEGIAIGSASALSPSDVIFCQYRESGVYLQRGFTLSSFMNQLFANSKDNGLGRNMPVHYGSKELNIHTISSTLATQIPHAAGAAYALKMQNIQNPDTEPRVAVCYFGEGAASEGDFHAALNIAATRQVPCIFICRNNGYAISTPTSDQYRGDGIASRGAGYGIATLRVDGNDIFAVRRATSHARRLALQDGGQPVLIEMMAYRVGHHSTSDDSFAYRQRVEVEDWKRRDNPITRLRKWLESRELWDEDKEKEVRSAMRKEVLRAFEEAEKEKKPSIRNAFEGVWENLTEEQRAHAEELKDVLERYPKEYDLEGFEGGIGGLEDMLKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ63</accession>
    <name>W6ZJ63_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964023">
        <property type="protein sequence ID" value="EUC43646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689829.1">
        <property type="nucleotide sequence ID" value="XM_007691639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ63"/>
    <dbReference type="GeneID" id="19125134"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6954"/>
    <dbReference type="eggNOG" id="ENOG502TGYF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105490_0_0_1"/>
    <dbReference type="OrthoDB" id="3799784at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="226" mass="24381" checksum="B143728CD392F446" modified="2014-04-16" version="1">MDHTASIVPSYPEAFPPLDTCTPITTQHNDIASPICAISSPTTTTTTPTTLDPLFQIHYETPLYTEINIPLPRLPPPRNPARTTKPSSPTSPTPTSPTTAQAPPRGRSKTLSSLSLFRTRRSSSTSSSSSQQPLSPSTSRPSTSSLASVSETQQQQQRPRKETVKSREVNALMDLRHQSKKGRSGTIDALAVVPAVLVLSAELFTPGEKGGRRKDSGVGRWEDGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJH4</accession>
    <name>W6ZJH4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_100060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964020">
        <property type="protein sequence ID" value="EUC43741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689739.1">
        <property type="nucleotide sequence ID" value="XM_007691549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJH4"/>
    <dbReference type="GeneID" id="19117596"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100060"/>
    <dbReference type="HOGENOM" id="CLU_132241_0_0_1"/>
    <dbReference type="OrthoDB" id="3913028at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="160" mass="17975" checksum="DBB88F205AF8B8C0" modified="2014-04-16" version="1">MVLLGANIRSTPVTTSNSERIKVSVLYGLDENSKKPILVFKLCSDAKGPEVKTECGLCAKLDNDKYPLLPFLYVTKKLISRRDSHLEILNKDLLLPSVLKWCFNAAIKASLVDVKLALLAGWRHKLTGAYKYLFIVSRAHHPWPEASMENHPESGVHELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK22</accession>
    <name>W6ZK22_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683148.1">
        <property type="nucleotide sequence ID" value="XM_007684958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK22"/>
    <dbReference type="GeneID" id="19120209"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22231"/>
    <dbReference type="HOGENOM" id="CLU_554306_0_0_1"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="494" mass="54481" checksum="D1620B2F64D6B581" modified="2014-04-16" version="1">MHFDLLSLKAKKSISQLLCRKNDTENNFAGIDRNLIERGTTPVPSPDKASVRPTANDSPSSNESPSRRKGLVGSLKENKLRSINSLRSLRSPTKAKQPDGDASPCTDSPHTPIPRPRSSLLLTFQESPADEPLFDLSRTDSTSFGHDFCYSSPLPIPSSENQNPQSFASPSVLPDGTIPSSPAPLRKLLDLDQNLNEDFPSPMFGPAFDLDLACVDLLVPLQDDMQEPHQIQGTSREMTGIVQAAVEHRHVPTKSPEREQPNTDGITELANDHRFIQEDSNVHKLTEKFDQHCINTNEGMADPSDNVLMIIGKEYMLRVFHNGDLKRRIGITAYDGQGYASSNDSEMILGRREEDFAAAERILPELGRFVVLNRDMLGNTSRELMLDEALAEGVLPEWLDLDLDMGSSERLHSRISNAGKRQNRESTWGQHAGLYDGTGYGTGSSSRSSTAAETGMDDACHYVEKGNPEDDVADILPGVYEKTYPFRSTPDSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKB0</accession>
    <name>W6ZKB0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964013">
        <property type="protein sequence ID" value="EUC44021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689426.1">
        <property type="nucleotide sequence ID" value="XM_007691236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKB0"/>
    <dbReference type="GeneID" id="19125010"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6583"/>
    <dbReference type="eggNOG" id="ENOG502RY5I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_2_1"/>
    <dbReference type="OrthoDB" id="64477at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43415:SF3">
        <property type="entry name" value="GNAT-FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43415">
        <property type="entry name" value="SPERMIDINE N(1)-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="43"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="246" mass="27969" checksum="D0020E0345260178" modified="2014-04-16" version="1">MSSKYPNPWRSPRLHYRAIRPCDKPIFLALTTDPAMYMASTHATLKLPTEQDADENMHQGPPSAGEGNSESLLQAIIWRPHDTPIASLPLEQKEAVLEEMKRVNPAQILDPEYGVAVGHIHSAPSSLHEAHHRTMEIALDILPAYQGKGYGSEAINWALDFGFRRAGLHSVRLRAFGWNKGAIRLYERLGFVVEGREREAVWFEGEWWDSFTLGMLDREWRAREAGKQEEAEFGHMDEEAQFGHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKF9</accession>
    <name>W6ZKF9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide SHNi-TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_88734</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685516.1">
        <property type="nucleotide sequence ID" value="XM_007687326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKF9"/>
    <dbReference type="STRING" id="930090.W6ZKF9"/>
    <dbReference type="GeneID" id="19127336"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88734"/>
    <dbReference type="eggNOG" id="KOG4563">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028900_1_0_1"/>
    <dbReference type="OrthoDB" id="5587616at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034080">
        <property type="term" value="P:CENP-A containing chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051730">
        <property type="entry name" value="NASP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019544">
        <property type="entry name" value="Tetratricopeptide_SHNi-TPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081:SF1">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10516">
        <property type="entry name" value="SHNi-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
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        <location>
            <begin position="212"/>
            <end position="249"/>
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        <location>
            <begin position="430"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10516"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="453" mass="49991" checksum="E6D6001CF8E17F19" modified="2014-04-16" version="1">MAEPTTEPLATVAETDDIPKTKEKLSELSQVASIHYSTKNFPAAAENYANAVEIQAELNGEMAPENAELLFYYGRALYKVAVAKSDMLGNKVAQEEKKNKQPKPKKAAKKETAEGLNAAKSQPKTESVENKPYFQLQGDENWTDSEDEDEEAQEDEQEEDDDDFGNAYEIFELARVLYEKQLQALKEGESGDKGKGKAELSPRERIIKERIADCHGFLVEISLENERFHDAVADARKSLALQEELYPFEHENVTEAHYSLSLALEFASVSKVREDQTGQSTDAPAETEQGKEDEDGVNWELRKEAAEQTDLAIQSLEARLKKEEAALDSDALKPEQKKEKQVIIDDKKGMLEDLKTRLVELKSDPTKQQFDSIDSSVFQGLLGGMMGADAATQKAKLAEAAKNANDVSGMVKKKAKPAAPAATSGPKDAGSSKRKLEVDDSGADEKRAKTEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKJ7</accession>
    <name>W6ZKJ7_COCMI</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_88628</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC48004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007687350.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
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        <property type="entry name" value="ARM-like"/>
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        <property type="entry name" value="ARM-type_fold"/>
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        <property type="entry name" value="TELO2-interacting_protein_1"/>
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        <property type="entry name" value="TPR_TTI1_N"/>
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        <property type="entry name" value="TTI1_rpt"/>
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        <property type="entry name" value="TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER"/>
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    </dbReference>
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        <property type="entry name" value="TELO2-INTERACTING PROTEIN 1 HOMOLOG"/>
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    </dbReference>
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            <begin position="7"/>
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            <begin position="726"/>
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            <begin position="716"/>
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            <begin position="792"/>
            <end position="803"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF24173"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF24181"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1060" mass="117633" checksum="46692C9FA4B2187C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKK9</accession>
    <name>W6ZKK9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_88292</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKK9"/>
    <dbReference type="GeneID" id="19127235"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88292"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="508119at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF21">
        <property type="entry name" value="QUINATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="469"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="39"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="542" mass="59127" checksum="89307323573D6D60" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL53</accession>
    <name>W6ZL53_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_98397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964006">
        <property type="protein sequence ID" value="EUC44336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689150.1">
        <property type="nucleotide sequence ID" value="XM_007690960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL53"/>
    <dbReference type="STRING" id="930090.W6ZL53"/>
    <dbReference type="GeneID" id="19129253"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98397"/>
    <dbReference type="eggNOG" id="ENOG502S3YT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_9_0_1"/>
    <dbReference type="OrthoDB" id="447842at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035539">
        <property type="term" value="F:8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006203">
        <property type="term" value="P:dGTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04678">
        <property type="entry name" value="NUDIX_MTH2_Nudt15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000060">
        <property type="entry name" value="Nudix hydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16099">
        <property type="entry name" value="8-OXO-DGTP DIPHOSPHATES NUDT15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16099:SF5">
        <property type="entry name" value="NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="162" mass="17906" checksum="1CAF23330234DF7A" modified="2014-04-16" version="1">MSEAQRPKVGVAAIIHDEAGNIIMGERAGSHGAGTFQCPGGHLEYSESFAATAAREVLEETGLEVGNIKFLTATNDVFGEGKHYVTIFVTCTIVGEEKVAKPMEPHKCAAWVWVPWSQMWAWAGEQAKAEKEGKEVKRKMFLPLVNLWREYPELEFALGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLE1</accession>
    <name>W6ZLE1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_34223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685154.1">
        <property type="nucleotide sequence ID" value="XM_007686964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLE1"/>
    <dbReference type="GeneID" id="19122517"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34223"/>
    <dbReference type="HOGENOM" id="CLU_104263_0_0_1"/>
    <dbReference type="OrthoDB" id="3692422at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="244" mass="26157" checksum="7B2E17DF1D28C80E" modified="2014-04-16" version="1">MQLQHKTQYPPVVHISVHVHPTSLTYAAHAHDAADDDDDSLAPPLDHHTTTSVPDTDCTRPKQMARQVAASVCTVSSPSILILTGAHGAATLIIIHPARLLPHPHHVVQVGPLGKGGARACVMQHLSELDALPIYEPRFLASSPMYTLSLYALPPPPPVQTESPAPWPAHALTCIQPGCTLPRPPTASASKWESSFATLLPTRNLLLHSPTLPIPVQNIHLHRPLGHPLSTSAPSRAQPLGYNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLV0</accession>
    <name>W6ZLV0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_37649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688941.1">
        <property type="nucleotide sequence ID" value="XM_007690751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLV0"/>
    <dbReference type="GeneID" id="19123295"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37649"/>
    <dbReference type="eggNOG" id="ENOG502SS8R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149482_0_0_1"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="128" mass="14504" checksum="CC51A2F0BD3AF7F2" modified="2014-04-16" version="1">MRIDIVFTFTSLLGMTDALRRSRRHNPRNWGKGRNDFNTHLPPGINLGLPCLPRRRYCRRNSPNGDGAYAIVSGGTLNSIAGIFCTIEDALAVENLHFIRNKAGIRTGWVIQDPCSFNQQSSSYRQYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM58</accession>
    <name>W6ZM58_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein mL38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_80144</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682416.1">
        <property type="nucleotide sequence ID" value="XM_007684226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM58"/>
    <dbReference type="STRING" id="930090.W6ZM58"/>
    <dbReference type="GeneID" id="19125610"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80144"/>
    <dbReference type="eggNOG" id="KOG3346">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035836_0_0_1"/>
    <dbReference type="OrthoDB" id="2153661at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1180:FF:000001">
        <property type="entry name" value="Mitochondrial large ribosomal subunit YmL35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.280.10:FF:000004">
        <property type="entry name" value="Mitochondrial large ribosomal subunit YmL35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF82">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC51068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="455" mass="51818" checksum="7505496D3F6D073F" modified="2014-04-16" version="1">MASTPSVRQFSACLRCVRQLPGAIGTRRLLSTSAVAHEEVQTQSANATRPPPPSNPPEGAAQNASPQAVPEFMQKWGTLDPQMVENKKQERRLLRREHVQPVGSRRRRAALRRSAIQKATEIPFEQLPYQCFQEARKFLLEDRQEKIKEIETQQLRIKNLMDQDPSVSGGPAAKEHRLRSMRKHLNELIILADINDPVVKRKFEDGQGDMNKPIYRYLADKKWRQYKRLVLEQRVTQLAIIPDILPSLDLVADIDLGFGRKSAAPGDFVDSAISEKMPRLNVQMFTPGEKLVTVVVVDADVPVPETDSFTYRCHLIASNIPLSPNNTSIPLQRIAQEDQKVEDPSAKKIALPWIAPWAHRGAPYHRLGIFVFEQNAGQALDVTKFNNVKRIGFNLRSFTDSNKLHPITATLFRTKWDDSMAGVMERAGMKSQINVEFKRKKVEPLPYKRRTERMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMG2</accession>
    <name>W6ZMG2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 15 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_21277</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682094.1">
        <property type="nucleotide sequence ID" value="XM_007683904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMG2"/>
    <dbReference type="GeneID" id="19120035"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21277"/>
    <dbReference type="eggNOG" id="ENOG502QS7A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010399_2_0_1"/>
    <dbReference type="OrthoDB" id="406733at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF0">
        <property type="entry name" value="GLUCAN 1,4-ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="TREH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trehalase-like N-terminal" evidence="3">
        <location>
            <begin position="78"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="GH15-like" evidence="2">
        <location>
            <begin position="349"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC51290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="738" mass="83707" checksum="0E3326ECCE03221E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMH1</accession>
    <name>W6ZMH1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U three protein 23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_33794</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in rRNA-processing and ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UTP23/FCF1 family. UTP23 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684722.1">
        <property type="nucleotide sequence ID" value="XM_007686532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMH1"/>
    <dbReference type="STRING" id="930090.W6ZMH1"/>
    <dbReference type="GeneID" id="19122408"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33794"/>
    <dbReference type="eggNOG" id="KOG3164">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053567_1_0_1"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09865">
        <property type="entry name" value="PIN_ScUtp23p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000006">
        <property type="entry name" value="rRNA-processing protein UTP23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057776">
        <property type="entry name" value="UTP23_sensor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24779">
        <property type="entry name" value="UTP23_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP23 sensor motif region" evidence="9">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="162"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00076388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="295" mass="33170" checksum="6BDBA9C235D00803" modified="2014-04-16" version="1">MKLKRAKAYKKQLHQYEVNFGFREPYQVLLDSQILQDAYNFKIDLVARIQKMLGGQVKPMITTCDMRHLYNAKPKNETLILQAKEYERRRCNHQDLDEPLSTHDCLSSVVDPKDNATNKHRYVVAANDSDTRAKMRTIAGVPIIYLAKSVVLMESMAEITEQHREREEKSKFKLGLKGQRKPDVPLKRKREDEGQDGEGSRSIEENSTGDAKPKPKKRKGPKGPNPLSVKKPKKEKTAAQSSATKKTRPSTSNTTDGGNRGNEGEDGAPRKRRRKHKPKAEGGDEAQGGEGPASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMX5</accession>
    <name>W6ZMX5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Survival protein SurE-like phosphatase/nucleotidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_2314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684592.1">
        <property type="nucleotide sequence ID" value="XM_007686402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMX5"/>
    <dbReference type="STRING" id="930090.W6ZMX5"/>
    <dbReference type="GeneID" id="19120378"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2314"/>
    <dbReference type="eggNOG" id="KOG2157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049222_2_0_1"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="entry name" value="Survival protein SurE-like phosphatase/nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027746">
        <property type="entry name" value="TTL"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551:SF1">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SurE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival protein SurE-like phosphatase/nucleotidase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="345" mass="37790" checksum="4716E59F2E72BE26" modified="2014-04-16" version="1">MHILVTNDDGPPSDQSSPYVHSLVSTLQKYGHTVSVVLPHTQRSWIGKAHLVGKSISPTYYRPEPLQTTAGGRLTNHGTTHNSPLPPSSNEEEWVLVDSTPASCVQIGLYHYFTERGPIDLVVSGPNYGRNSTAIFSLSSGTIGGAMEAAVCGMKSIALSYAFFDRNHDANIISGASELSAKLIQYLWDNWDKNTHLYSVNVPLVENVGERKVLWTNMLQNTWKSGSCFQVVEVPSEADDKPADIEGQIRKQEEKLGKKELKSNSENAGGASGTDSGQDTPSGQPHSRYTHKHFKWAPSFKDVYQSVEESEPGNDGWAVAQGFTSVTPLRANFMHVNGFEGEIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN20</accession>
    <name>W6ZN20_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_79451</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682269.1">
        <property type="nucleotide sequence ID" value="XM_007684079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN20"/>
    <dbReference type="STRING" id="930090.W6ZN20"/>
    <dbReference type="GeneID" id="19125476"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79451"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031576_0_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11070">
        <property type="entry name" value="CYP56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF223">
        <property type="entry name" value="CYTOCHROME P450-DIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC51403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="58001" checksum="8CDC1C3273EA23D8" modified="2014-04-16" version="1">MVSYLSLVFVGAFAAIFGVFTFFVYLFTPPRNFPKDIPTIPFYYGLLPLFKDVDQAELYREYLKEPLARYGAVKLFFGGQWNILVTKPAYIAEVFKQEDTYAKSGNQVKIPHSVLAEYTGENIISAHGEKWKLYQRVIKPALQADQDSESIWKNSRILRDMFLSESKNTRGNRVPVYALLHRYALANLGEVLYGSSFETLQNASAPLHTLQTKIKPIIFHPIFLNFPFLDHLPLKIRKLGRVLSRQFRGTLRSAIAKGHTQHVCNENDNRNVACRLLGSHREGILSDKDLDDNLVSTFLAGHENPQLALMSLMYLLGKHTHVQDAVRKEIAALYPSNAPADYEPDYSDIHDLPLLTSVLYESLRMFPPISQLINRRTTTPVVLGNTVPVPAGVYMGYNAYSTNRDTEFWGTDADDFKPERWGTTNEDINKLYRRANSKSAFISFHGGRRACLGQKFAMQQLRITLVQLVRDVKWKLDETWDGRMTPAGPLYPRGLKLKFESVHQVSEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNY2</accession>
    <name>W6ZNY2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_96011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688212.1">
        <property type="nucleotide sequence ID" value="XM_007690022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNY2"/>
    <dbReference type="GeneID" id="19128768"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96011"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_2_2_1"/>
    <dbReference type="OrthoDB" id="1935484at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000247">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000106">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF14">
        <property type="entry name" value="MFS GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
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            <end position="510"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="63053" checksum="DCF577C547266E04" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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            <begin position="1"/>
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        </location>
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            <begin position="17"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="250" mass="26777" checksum="651DD76EF458E044" modified="2014-04-16" version="1">MLPVLLVLFGHFSAGGLVGPSRPGQGRCSPQLIARLPLVSCAPPSNKKETCCPPHCKTNIFKPLSFPRFFAPRTRTCTCTPCLPCPALHCTGACVLSERGTLHACDPNHVCIEFQWDTLLLLLLLLLLLHANAHPPASPSTATLCASLQLRYPSLNHAHSFAPRCKGLPCSGQRAPPPLPRPQPSPAGPNGCAWLAPAFSSCACAPYTTLLTAKTCRRPPSLLASTPTWRSRETFKAWQADVSDAQCGIT</sequence>
</entry>
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    <accession>W6ZPJ9</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889973" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="18946" checksum="A78830D40D28D52C" modified="2014-04-16" version="1">MADMLGGLLALVQASTCAVPYPCRLCWGRDKGNPEFVMVIVYDGCSTAPIFTALGSANRSSVSRSSPTGQQVYPPIHCGLQRGIVALPQSPFYLLNASPTTSHTARNAVCPGSGSLQADLRPGANFRSIHPPEFFCVPSTMPMQHEAYNGTYDMPVPHFAHGTMCRFIRALDATPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPV5</accession>
    <name>W6ZPV5_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
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        <name evidence="5" type="ORF">COCMIDRAFT_1762</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685755.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZPV5"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_1762"/>
    <dbReference type="eggNOG" id="ENOG502QQXX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006632_1_1_1"/>
    <dbReference type="OrthoDB" id="2264294at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
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    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="80"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC49514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="697" mass="78209" checksum="7692BF769A455FB8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ50</accession>
    <name>W6ZQ50_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_84128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683918.1">
        <property type="nucleotide sequence ID" value="XM_007685728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ50"/>
    <dbReference type="GeneID" id="19126401"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84128"/>
    <dbReference type="HOGENOM" id="CLU_163488_0_0_1"/>
    <dbReference type="OrthoDB" id="10494613at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="89" mass="10318" checksum="5029D144F433DE3D" modified="2014-04-16" version="1">MPTRLAKGIVQSWGCNGMLWYDMWCYDISYIVCRVSEWGIWGGIGRNRMMQESETTEEKKNTKGKTTCQHDEVVRVKADGGLEVKIDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ98</accession>
    <name>W6ZQ98_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-ornithine N(5)-monooxygenase</fullName>
            <ecNumber evidence="5">1.14.13.196</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">L-ornithine N(5)-oxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_36413</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-ornithine + NADH + O2 = N(5)-hydroxy-L-ornithine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41512"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-ornithine + NADPH + O2 = N(5)-hydroxy-L-ornithine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41508"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.196" evidence="5"/>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687573.1">
        <property type="nucleotide sequence ID" value="XM_007689383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ98"/>
    <dbReference type="STRING" id="930090.W6ZQ98"/>
    <dbReference type="GeneID" id="19123021"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36413"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020931_2_0_1"/>
    <dbReference type="OrthoDB" id="3519933at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000195">
        <property type="entry name" value="L-ornithine N(5)-monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802:SF1">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="Lys_Orn_oxgnase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC45906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="529" mass="59074" checksum="8F6F9C75A40AE141" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSE4</accession>
    <name>W6ZSE4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_81932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683073.1">
        <property type="nucleotide sequence ID" value="XM_007684883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSE4"/>
    <dbReference type="GeneID" id="19125959"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81932"/>
    <dbReference type="eggNOG" id="ENOG502SQ6I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077197_0_0_1"/>
    <dbReference type="OrthoDB" id="4232400at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054722">
        <property type="entry name" value="PolX-like_BBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40628">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40628:SF1">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22936">
        <property type="entry name" value="Pol_BBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel" evidence="2">
        <location>
            <begin position="20"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="367" mass="42171" checksum="6DAD3C31D1AF0687" modified="2014-04-16" version="1">MAAHGTTPICPDWIFLDNSNVHVAKDRGWFMTYTPFNSYIKSSLFCSPRYLPVLGVGTVRIPTKCSSTQSGISNHSYLRLEQVLHVPGFICNVISSSVMISDGYNIQKHVSRRSKGAVKDRSGKQIAFFNRNTPHYSIRVRSRPEGPRLGPHVLRKNGMYMISCYWVHNGEQKCHWEQSEEQKWLDYKAGDCDKYSKSVSAIATGTSSSDTNANPPYTKAEKRFLEDSCDGEYEFLFNHGLDFYNSEDRERSRLLLRALMRREGLDGECADEEESDDEEEEEEEEEDEEESNNEEEGSNYSFDDAELYDPAEFSSEELKWVRTHYRDVDAFMAAYGLNPNWFYDRMDARGMVNGLLKEEKLANAVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSQ2</accession>
    <name>W6ZSQ2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_81519</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682877.1">
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    </dbReference>
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        <property type="entry name" value="Ankyrin_rpt"/>
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        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
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        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
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    </dbReference>
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        <property type="entry name" value="PROTEIN FEM-1 HOMOLOG CG6966"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="494"/>
            <end position="527"/>
        </location>
    </feature>
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        <location>
            <begin position="200"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="585" mass="63357" checksum="FCB756AD5A388A09" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZT05</accession>
    <name>W6ZT05_COCMI</name>
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        <recommendedName>
            <fullName evidence="9">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="10" type="ORF">COCMIDRAFT_4114</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exportin family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC46826.1"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:kinetochore"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071528">
        <property type="term" value="P:tRNA re-export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000469">
        <property type="entry name" value="Crm1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000490">
        <property type="entry name" value="CRM1p Major karyopherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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        <property type="entry name" value="CRM1_repeat"/>
    </dbReference>
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        <property type="entry name" value="Exp1_repeat_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
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        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
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        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014877">
        <property type="entry name" value="XPO1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040485">
        <property type="entry name" value="XPO1_repeat_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CRM1_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18784">
        <property type="entry name" value="CRM1_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18787">
        <property type="entry name" value="CRM1_repeat_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01102">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="26"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1039"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1039"/>
            <end position="1053"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC46826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1069" mass="122618" checksum="44776A815EB71A6C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX33</accession>
    <name>W6ZX33_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_2668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685000.1">
        <property type="nucleotide sequence ID" value="XM_007686810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX33"/>
    <dbReference type="STRING" id="930090.W6ZX33"/>
    <dbReference type="GeneID" id="19120973"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2668"/>
    <dbReference type="eggNOG" id="ENOG502SQG8">
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    <dbReference type="HOGENOM" id="CLU_035845_0_1_1"/>
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        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYP0"/>
    <dbReference type="GeneID" id="19120602"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2450"/>
    <dbReference type="HOGENOM" id="CLU_2654124_0_0_1"/>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC48796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="76" mass="7993" checksum="67055C7FC32D72DD" modified="2014-04-16" version="1">MPPADPNISQSDRLCPSLNALSYVSGVCIALMRLAEVLATGVSPYNGLNFPIIGSHTSVHIAAEINGPVEGWVMKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYR3</accession>
    <name>W6ZYR3_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
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            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007686431.1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_33698"/>
    <dbReference type="eggNOG" id="KOG0029">
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    </dbReference>
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    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="554" mass="60732" checksum="97C7836BA0A6BF74" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W7A241</accession>
    <name>W7A241_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963926">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A241"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_22416"/>
    <dbReference type="eggNOG" id="ENOG502SW6C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_765016_0_0_1"/>
    <dbReference type="OrthoDB" id="5431248at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="362" mass="39935" checksum="C68CACBDBDC234DC" modified="2014-04-16" version="1">MDIDDALPPPIRRSPRAALEARKQRSEYRTFIFDDINEQGDEAPLPPIAPDESASVRRNGYNEPTLHESVSPGVNPLRSHPVGAPSPRNLARKYSYPLLVSEPKDGTSPDPTPVIEPPASRRHPRGLVSYRNNKRELKINKKLPPHLRRQTSLETINSVTTTASDNQSEDSHDPPEAEAPCSEWYAMEDDLYSNPPPSIISKASSTHSSISSSIQSTTPVETPLEYASLDHHTPQSLFRKMMPRKLSDKTQDGSSSPSRLVIEKTTSVNRSSSSFTLSGSTTSPSEEYRSLHSIREEVGRDRSASKSSGSSKWSASDFDTSTLSEAELKRCKKKGINPALYAEMRAAKKGRWASPIAGNTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W7A442</accession>
    <name>W7A442_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_81139</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682773.1">
        <property type="nucleotide sequence ID" value="XM_007684583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A442"/>
    <dbReference type="STRING" id="930090.W7A442"/>
    <dbReference type="GeneID" id="19125809"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81139"/>
    <dbReference type="eggNOG" id="KOG0801">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1819">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022550_2_0_1"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070936">
        <property type="term" value="P:protein K48-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15737">
        <property type="entry name" value="FYVE2_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16489">
        <property type="entry name" value="mRING-CH-C4HC2H_ZNRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051878">
        <property type="entry name" value="ZNRF_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46661">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46661:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="15" id="KW-0458">Lysosome</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0519">Myristate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="20">
        <location>
            <begin position="194"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="19">
        <location>
            <begin position="546"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="289"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="480"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="492"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC50816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="592" mass="64927" checksum="C860F08F5364F8D1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W7A537</accession>
    <name>W7A537_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_79766</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682176.1">
        <property type="nucleotide sequence ID" value="XM_007683986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A537"/>
    <dbReference type="STRING" id="930090.W7A537"/>
    <dbReference type="GeneID" id="19125542"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79766"/>
    <dbReference type="eggNOG" id="KOG0058">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18573">
        <property type="entry name" value="ABC_6TM_ABCB10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000048">
        <property type="entry name" value="ATP-binding cassette sub-family B member 10, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000218">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002773">
        <property type="entry name" value="ABC_prm/ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="226"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
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            <end position="470"/>
        </location>
    </feature>
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        <location>
            <begin position="503"/>
            <end position="740"/>
        </location>
    </feature>
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        <location>
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            <end position="781"/>
        </location>
    </feature>
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            <end position="759"/>
        </location>
    </feature>
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        <location>
            <begin position="760"/>
            <end position="773"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005580"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC51211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="781" mass="84114" checksum="03389F45A0812433" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W7A5I2</accession>
    <name>W7A5I2_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">DSBA-like thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_193</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_193"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="DsbA_FrnE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13887">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13887:SF41">
        <property type="entry name" value="THIOREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="5"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="219" mass="24772" checksum="DB73CEFBF7C372F9" modified="2014-04-16" version="1">MTNFQVNIVSDTVCPWCYVGKKRLEKGIAAYKEKHPDSNDTFSTSWFPFYLNPSAGKSMNKEQVWASKFGKERTIMMKERLTEVGKAEGINFKYGGNTGNTRDSHRLVQLGKTKGPQVQTRVIEELFAAYFENEKDITTHEVLTEVGVKAGLDEKEVKEWLESGKGGPEVDREVEQARQQHITGVPNFTINDQYEVSGAQDPAAFVQLFERLKKQEGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YL86</accession>
    <name>W6YL86_COCMI</name>
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        <recommendedName>
            <fullName evidence="9">Metal homeostatis protein bsd2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_110039</name>
    </gene>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EUC39962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YL86"/>
    <dbReference type="STRING" id="930090.W6YL86"/>
    <dbReference type="GeneID" id="19119535"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110039"/>
    <dbReference type="eggNOG" id="KOG4812">
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    </dbReference>
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    <dbReference type="OrthoDB" id="10003116at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031398">
        <property type="term" value="P:positive regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22212">
        <property type="entry name" value="NDFIP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019325">
        <property type="entry name" value="NEDD4/Bsd2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396:SF5">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN 1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10176">
        <property type="entry name" value="NEDD4_Bsd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC39962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="37115" checksum="CC63243F7EF144A7" modified="2014-04-16" version="1">MPSQRYERVAAQDEDDSHASSTSAQQWPPASPPPSFHSRASSPNGTSRRLLAQDPAPTDEDRTLADTFDSDSDDDDDDNGDDRQRLMRGNPRSEDEPPAPGIQRRVTELPVFNTQAPTSGRVYGGGNGGVWANLSAKPTRGEDAEEKPPTYEQAAADATPPYWETTILAPGTFGDEVFVEGLPVGSLFSFLWNAMISMSFQLVGFLLTYLLHTTHAAKNGSRAGLGITLVQFGFGFRSAVLNPSNGSNDNPGQGFNGGVPSDPNSHDFDPDKVSTGSSGGDSTPTSSAITGSDWVAYGLMIVGWFILIKSVSDFIRARRHEQLVLQSPDRGLGVAVVAEGESPERSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMF1</accession>
    <name>W6YMF1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC40467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMF1"/>
    <dbReference type="GeneID" id="19119300"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108738"/>
    <dbReference type="HOGENOM" id="CLU_3147106_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="49" mass="4990" checksum="DE76317A7E6D593C" modified="2014-04-16" version="1" fragment="single">ARLGWVANLLTTHRHGFAKGEGGRGEGTRGGGAGSALSLTRHGRSLFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YP09</accession>
    <name>W6YP09_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_106996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964118">
        <property type="protein sequence ID" value="EUC41132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YP09"/>
    <dbReference type="STRING" id="930090.W6YP09"/>
    <dbReference type="GeneID" id="19118958"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106996"/>
    <dbReference type="eggNOG" id="ENOG502S4EX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017006_2_0_1"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06197">
        <property type="entry name" value="FNR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815:SF2">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="348"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="599" mass="65462" checksum="54E4E34B451299CD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPQ8</accession>
    <name>W6YPQ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_10404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964373">
        <property type="protein sequence ID" value="EUC39503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695788.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_10404"/>
    <dbReference type="HOGENOM" id="CLU_1563838_0_0_1"/>
    <dbReference type="OrthoDB" id="3682743at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="45"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="171" mass="18944" checksum="0B1D091287B55A1A" modified="2014-04-16" version="1">MSDWIGPNVYRIESHKDRKTAVTVKDGNKDDGAAVVLKASDANKNDHWQFVHVGTGVSGKEEFLIINCNTGYHLTYAEEAKQAPLTVTRNSPTHYRCRWNIAPTRNGTGAFWIVAAKDNKMMLVTEGEKTIDNVNLQIWKGTVGSLGTWWYLKLVDGQTLQSADLGKAPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQL7</accession>
    <name>W6YQL7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADPH-dependent 1-acyldihydroxyacetone phosphate reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_10067</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964217">
        <property type="protein sequence ID" value="EUC39955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693529.1">
        <property type="nucleotide sequence ID" value="XM_007695339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQL7"/>
    <dbReference type="STRING" id="930090.W6YQL7"/>
    <dbReference type="GeneID" id="19117722"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10067"/>
    <dbReference type="eggNOG" id="KOG1209">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_1"/>
    <dbReference type="OrthoDB" id="2102561at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000140">
        <property type="term" value="F:acylglycerone-phosphate reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC39955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="29202" checksum="0368B8D97525DB03" modified="2014-04-16" version="1">MTTKAKTVVITGCSANSIGEALAFEFHRNGYMVCATCLPNEQLTEMEALGMICCPLDVTNDDSVAKFSEFLHEHYRGIDVLVNSAGINYVMPILDLDMTELRRIFDINVFGMVRVTQTLSDLLIKNQGAYNGSKAALLAMGNTLRIELGPFGVKVMTILAGPIASGLMTRTIRTLPSSSLYLPVKEEFESRMSHKSHGVDTLSRSKFAEAVVAKVEKPPFNFWIGPWNRVVWVLETFGLLSIWDRIFRKMFKLDKLRKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQV9</accession>
    <name>W6YQV9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_109903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964209">
        <property type="protein sequence ID" value="EUC40015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693473.1">
        <property type="nucleotide sequence ID" value="XM_007695283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQV9"/>
    <dbReference type="GeneID" id="19119516"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109903"/>
    <dbReference type="HOGENOM" id="CLU_1686249_0_0_1"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33734">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING GPI-ANCHORED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33734:SF22">
        <property type="entry name" value="MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886117" description="LysM domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="42"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="108"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="156" mass="15720" checksum="5A3C02624B9693C5" modified="2014-04-16" version="1">MLSILVLTTTFAAAVLGSPHSRPPTPIVTPTPIVARQCGGIATHVVAQGDTLSRIAAQLGVGVCNIAASNHIENINTIYASQTLTVRASGCEAVNHGPECTLLPKLAGVHVAVAGDTFWKLAAAQGLPATAIITANPAIPTNAIPIGQAIVIPAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR07</accession>
    <name>W6YR07_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7770 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964082">
        <property type="protein sequence ID" value="EUC41877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691599.1">
        <property type="nucleotide sequence ID" value="XM_007693409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR07"/>
    <dbReference type="GeneID" id="19123788"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40003"/>
    <dbReference type="eggNOG" id="ENOG502TF8D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081383_0_0_1"/>
    <dbReference type="OrthoDB" id="3527137at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056672">
        <property type="entry name" value="DUF7770"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24968">
        <property type="entry name" value="DUF7770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7770" evidence="1">
        <location>
            <begin position="28"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="194" mass="22659" checksum="B2E7591EA6A50D0A" modified="2014-04-16" version="1">MPSISHIVALEEQNREYFNNNTSTFSKIRVTIHTTGAWPNSLHSNNHVTTLLLLDRGGAVQVNMRTDDGDRRGQLQWKLVNYRHSSSEVKCIDYELYAPVQVKTLYRAIRHDWKLHQYLFSSGGTGCRYWTYVLLDTMSNDTRRFALHPGVPAHAWGVFGKSYSRSGAERPCNPIRQDQFQSYEEWWNDWFTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRT9</accession>
    <name>W6YRT9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964188">
        <property type="protein sequence ID" value="EUC40193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693288.1">
        <property type="nucleotide sequence ID" value="XM_007695098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRT9"/>
    <dbReference type="GeneID" id="19121753"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30830"/>
    <dbReference type="eggNOG" id="ENOG502S92K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064039_0_0_1"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052358">
        <property type="entry name" value="Aro_Compnd_Degr_Hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563:SF2">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889360" description="Amidohydrolase-related domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="62"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="339" mass="38002" checksum="CB6E758A32B73CCC" modified="2014-04-16" version="1">MAFTRIILVTVLLSCIQIFVTNAQPYLRTVARSAKLAPSIANQHVAYDNNATIAKRIPAHSWDTHMHVTDPNYPEVAGAEYTPGLHNLSNALSFESTIGMRNIVIVQPSIYGNDNTLLINALTKLGTRHGRGVVGFDANTISFETLREWDKLGVRGVRLNIKSNNITLTKAQLQAQVKHYAQIIKPLNWVLELYIGMEDFPKLEPIVADLGVTLSIAHFGAPNLPPPENRTIPFDPYSLVGFQSLVNLLKGGNTYLKFSGAYRFDKDPEYGGVEGIARELLKFAGDRIIFASDWPHTRFEGLDIRPFVEKVLDWTEETNLKEKVFSRNAHVLWDIPLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS03</accession>
    <name>W6YS03_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_41364</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964179">
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
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                <person name="Han J."/>
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                <person name="Lindquist E."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="645" mass="72741" checksum="DB201BB351897F46" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUF8</accession>
    <name>W6YUF8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_101717</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690365.1">
        <property type="nucleotide sequence ID" value="XM_007692175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUF8"/>
    <dbReference type="GeneID" id="19117919"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101717"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_0_1"/>
    <dbReference type="OrthoDB" id="4500315at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000396">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="521"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="564"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="609"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="636"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="674"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="704"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="138"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="69"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="322"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="322"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="354"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="416"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="453"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="742" mass="82381" checksum="E3A31AB9C668A585" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV74</accession>
    <name>W6YV74_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exosome complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_50233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the C1D family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964102">
        <property type="protein sequence ID" value="EUC41448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV74"/>
    <dbReference type="STRING" id="930090.W6YV74"/>
    <dbReference type="GeneID" id="19124469"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_50233"/>
    <dbReference type="eggNOG" id="KOG4835">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064339_1_0_1"/>
    <dbReference type="OrthoDB" id="1421013at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011082">
        <property type="entry name" value="Exosome-assoc_fac/DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341:SF3">
        <property type="entry name" value="NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341">
        <property type="entry name" value="SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="136"/>
            <end position="300"/>
        </location>
    </feature>
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        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
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            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="300" mass="33531" checksum="0B86A6E3BDBD5E4B" modified="2014-04-16" version="1" fragment="single">MDPQIDLPDLVEDLEVDIDELTTALEPLLSKPLSTTASSLPLLDKAKLYCLAAYAIESLLFASLTASGVNATEHAIFKEIARLRQYNSKIKEIEDRGIKGSAEGRARLDVAAAGRFIKHGLSGNDKYDLERQERMAKERARAHLKAQQINKKFDNEGKEVQKGQNVTPKKRGVEEQEEQDGSDEQVLEGLEEEPAVKKARVQDGAEADTARPRKRGRPSKKDRKAEEAQTRTTRKRNTRLANQDAEENQEEEGQAEEEEEEEGEDDVEVPDQAPKTRSETFTALLDGSLSEKHKQKKAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVF8</accession>
    <name>W6YVF8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_8796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
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        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="78"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="601" mass="69393" checksum="8401F684640DED34" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
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        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886167" evidence="1">
        <location>
            <begin position="20"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="119" mass="12896" checksum="5E680632DA4983B5" modified="2014-04-16" version="1">MIISGSIVAIVTLLPTVWSVPTNYTNKLPTCGANECLTDGYFDGCAPGNLICICNLEQDDVDRYVKTVQPCLDGKPGKKACTLGAVANYKQLLADVCSKPEYGNLNKTVSFEPVYYPPR</sequence>
</entry>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="432483at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="257" mass="28415" checksum="69C5E3EB03A17617" modified="2014-04-16" version="1">MDPLSITASAIGITAFATSSIVQLRNIIDGLSEAQDVVADVASSLANIERPLAALERLSISDESTSVAAKEDLRKAGVAEAVNECGNICNKFSKNLSKWTKHSSSTKLSLRDRLSVGVWNREKIRTLNTQLQSMVQLRSEKTSETDRENVKRQLQTLETKIQEHLDLTKRQQDQALERKRALEEEPEDEEDGGAQRMLAIKEVEQQSRLLEADQVSCGVVFSQVRSKRSGQEISNIITLDNSKALVGLLESVIGKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWB1</accession>
    <name>W6YWB1_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964242">
        <property type="protein sequence ID" value="EUC39824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693658.1">
        <property type="nucleotide sequence ID" value="XM_007695468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWB1"/>
    <dbReference type="GeneID" id="19117898"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10164"/>
    <dbReference type="eggNOG" id="ENOG502RXHN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072358_1_0_1"/>
    <dbReference type="OrthoDB" id="5030973at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="313" mass="34483" checksum="5D193B7B663C4C14" modified="2014-04-16" version="1">MAEVSNNDLVQTEEEYENDGDGDGDDDDDDVFDIMLNPGGDEGSSFRTRNDPSAPYQRANVTERKGALDIRCACLDVIHGLMSPDADEFATIIVLNFRFDSRKTARRILAVNITLQFAPEQPGDPEPEVFQITPFDSMVMVQTMQTEEKKIMAGVNLGAPPLAGVELGVDLGWERSVNRETTDATRVIGSIDLLGRTYGNADSASWSLIENSTTKTGVPSTMRTAILLKRQDEKPFRCDFKIEAKVDPKSSIERSFQRLFGGRPKDDPLLFDPQLPPTNKLQMYDLTALGSVDLGSLSGVTFQTVLDSAVKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWI3</accession>
    <name>W6YWI3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
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    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_52760</name>
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    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964082">
        <property type="protein sequence ID" value="EUC41883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691607.1">
        <property type="nucleotide sequence ID" value="XM_007693417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWI3"/>
    <dbReference type="GeneID" id="19124556"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_52760"/>
    <dbReference type="HOGENOM" id="CLU_000134_45_3_1"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="87" mass="9727" checksum="D857D7DEF15AD3FD" modified="2014-04-16" version="1" fragment="single">TALHLTSMLGMVHHVQQLLQESGTDVNVTNDDLQTPLALAVRNNRARVVELLLHVESIDCEQKDKLGRTPFLIAAELKDTNIMKQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWL2</accession>
    <name>W6YWL2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein mS41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_104801</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS41 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964079">
        <property type="protein sequence ID" value="EUC41945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691531.1">
        <property type="nucleotide sequence ID" value="XM_007693341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWL2"/>
    <dbReference type="STRING" id="930090.W6YWL2"/>
    <dbReference type="GeneID" id="19118576"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104801"/>
    <dbReference type="eggNOG" id="ENOG502SCMV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087049_0_0_1"/>
    <dbReference type="OrthoDB" id="18595at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039603">
        <property type="entry name" value="Ribosomal_mS41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019083">
        <property type="entry name" value="SAM_Ribosomal_mS41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28235">
        <property type="entry name" value="PROTEIN FYV4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28235:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09597">
        <property type="entry name" value="SAM_Ribosomal_mS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01238">
        <property type="entry name" value="IGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS41 SAM" evidence="6">
        <location>
            <begin position="44"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="210"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="242" mass="26407" checksum="6480DA24F43B0258" modified="2014-04-16" version="1">MILRRPLLNATSAAVSIPKTCVRNLQHSIPMRPVPKPIPFIPDHTAFLSAIGRGLSAHATKIPSWEALFTLTSPQLKELGVEPARARRYLLHWREKFRNGEYGIGGDCKHVTDGVAELKVVEAPVPPNPQLGNTISPRSALATATHDPGTRKLVVNVPVGADTPPEPVETLPKVQGVVVKGANTIKGSFVEPVKGSGGLRARIRLQEGIWEERRGHKVDGGERRKAEVRAKRRAAENKEKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWZ5</accession>
    <name>W6YWZ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_99594</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689572.1">
        <property type="nucleotide sequence ID" value="XM_007691382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWZ5"/>
    <dbReference type="STRING" id="930090.W6YWZ5"/>
    <dbReference type="GeneID" id="19129498"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99594"/>
    <dbReference type="eggNOG" id="KOG0834">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022000_7_0_1"/>
    <dbReference type="OrthoDB" id="25002at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000072">
        <property type="entry name" value="Cyclin Pch1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000201">
        <property type="entry name" value="Cyclin pch1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028758">
        <property type="entry name" value="Cyclin, C/H/G types"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="34"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="153"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="245"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC43912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="306" mass="34855" checksum="A30CC715E739C70B" modified="2014-04-16" version="1">MQWIFTEEELLLAPSITDGMAPEEERTLRRKGVGFILQVGMMLKLPQTTLSTAAVFFNRYLMRMSLKPRPGYKPLHHYQIAATALFLATKVEENCRKMKELVVSCVRVALKDPNKLVDEQTKDFWKWRDTILYSEDVLLEALCFDLNVESPYKIMYDMMKYYGVEHNKKLRNSAWAFLSDSTSTQMCLLFPSRTIATASLYAGARMAEVELSDDDGKPWWEIQHIQLRDIRKACNLMADLYEKTPDKDGEPNMYAGLRTPEDGIDFGDTPRSMEGVQMTSQSQPTANGTADGNVTERGSEEGELDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXJ9</accession>
    <name>W6YXJ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_8126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
    <sequence length="411" mass="45887" checksum="049115FB7FFE9309" modified="2014-04-16" version="1">MADADQTPLPLPVPSLTRLAPGVILSQPLSRKGSGPGLIVIVNQSGATNDTTLRIENGVPSPLMKWGEESYTVVELLEEAFLEGKDPISLAVSELSKADKCEPKNAIGVIAYDLKLWNRAAPYLTSHPSIVGAVVYADAAEHHKLAMTSVPVLQHMAGKMRKPPRTETRVVHDYPNAKSHLFATPFQPEFDYNMESVSHTRNLSFLKPRMNGPWFDLEAIWDEHTYWEFENRSVPQTMATMVQEPYVNHVPTLTGGIGREALTDFYTNHFVYSNPKDIETELISRSMGIDRVIDEFIFKCTHDAPLDWLIPGIPPTGRKLEIPFMAVVNIRGDRLYHEHIAWDQGTVLAQLGLLPEYLPIPYALPSGQNQDGNKLEYKLPITGVETAQKLRNKDAVTSNVMLGFQVRNKNA</sequence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">ATCC 44560</strain>
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    </dbReference>
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        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        <location>
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        <location>
            <begin position="974"/>
            <end position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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        <source>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="OrthoDB" id="3687409at2759"/>
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    </dbReference>
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        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
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        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="73" mass="7993" checksum="04280D573FB62C29" modified="2014-04-16" version="1">MAPVSLHQSSHPFLTPTRASDISSWTLSVPERSSNSSTQSTDAQSRQAAIEAYRQMKAALFSRSLHSNLSRST</sequence>
</entry>
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    <accession>W6Z051</accession>
    <name>W6Z051_COCMI</name>
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        </submittedName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="75"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="102" mass="11535" checksum="25EC360C516A63AF" modified="2014-04-16" version="1">MFVVVAWRGTYSDVAHTMHLISIRHARSIRRRMYLLEDDDGNGDNNDDDDNNDDDDNNDDDDNNDDDDNNDDDDNGSMRLSADAVDVGNYFHATAPCPIRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z056</accession>
    <name>W6Z056_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Rad4 beta-hairpin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_7285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPC family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC43245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690213.1">
        <property type="nucleotide sequence ID" value="XM_007692023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z056"/>
    <dbReference type="STRING" id="930090.W6Z056"/>
    <dbReference type="GeneID" id="19125239"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7285"/>
    <dbReference type="eggNOG" id="KOG2179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003639_1_0_1"/>
    <dbReference type="OrthoDB" id="300780at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000111">
        <property type="term" value="C:nucleotide-excision repair factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071942">
        <property type="term" value="C:XPC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Rad4, beta-hairpin domain BHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.290">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rad4, beta-hairpin domain BHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.260.10">
        <property type="entry name" value="Transglutaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BHD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004583">
        <property type="entry name" value="DNA_repair_Rad4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018325">
        <property type="entry name" value="Rad4/PNGase_transGLS-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018326">
        <property type="entry name" value="Rad4_beta-hairpin_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018328">
        <property type="entry name" value="Rad4_beta-hairpin_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042488">
        <property type="entry name" value="Rad4_BHD3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036985">
        <property type="entry name" value="Transglutaminase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135">
        <property type="entry name" value="DNA REPAIR PROTEIN XP-C / RAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10403">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10404">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10405">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03835">
        <property type="entry name" value="Rad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01030">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01031">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01032">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="7">
        <location>
            <begin position="524"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="8">
        <location>
            <begin position="584"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="9">
        <location>
            <begin position="653"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="342"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="601"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="797"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="868"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="605"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="883"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="900"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="931"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="948"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="962"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="981"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC43245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="997" mass="110890" checksum="ECD221071EDD6689" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0D0</accession>
    <name>W6Z0D0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_5565</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Non-reducing polyketide synthase; part of a gene cluster that mediates the biosynthesis of a yet unidentified natural product.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007690083.1"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    <dbReference type="GO" id="GO:0008168">
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0016491">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Probable polyketide synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000011">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.110:FF:000001">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="387"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="1315"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="1706"/>
            <end position="1783"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1315"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1478"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1637"/>
            <end position="1702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1642"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1692"/>
            <end position="1701"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="1347"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00055753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC45162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1784" mass="195166" checksum="3A83F116C4F9379C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z138</accession>
    <name>W6Z138_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_7169</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
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        <property type="protein sequence ID" value="EUC43408.1"/>
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        <property type="nucleotide sequence ID" value="XM_007691879.1"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017149">
        <property type="entry name" value="GSH_degradosome_Dug2"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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        <property type="entry name" value="WD40_repeat_CS"/>
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    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF8">
        <property type="entry name" value="DI- AND TRIPEPTIDASE DUG2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037237">
        <property type="entry name" value="Peptidase_WD_repeats_DUG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="189"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="392"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="463"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="9">
        <location>
            <begin position="700"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="25"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="270"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="921"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="929"/>
            <end position="946"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC43408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1033" mass="113863" checksum="9D1ABD4C7BC18D33" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1Z9</accession>
    <name>W6Z1Z9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavoprotein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_100109</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964021">
        <property type="protein sequence ID" value="EUC43728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689786.1">
        <property type="nucleotide sequence ID" value="XM_007691596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1Z9"/>
    <dbReference type="STRING" id="930090.W6Z1Z9"/>
    <dbReference type="GeneID" id="19117607"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100109"/>
    <dbReference type="eggNOG" id="KOG0672">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033319_3_0_1"/>
    <dbReference type="OrthoDB" id="1532798at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071513">
        <property type="term" value="C:phosphopantothenoylcysteine decarboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359">
        <property type="entry name" value="HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359:SF6">
        <property type="entry name" value="PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="3">
        <location>
            <begin position="39"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="269" mass="30280" checksum="F8ABDB36F5DB8A01" modified="2014-04-16" version="1">MTADIRDLKPLNIRPVQHQVRDPPEADPFAFDHHDDKIHVLLCASGSVATIKIPNIINALAKHANVQIRLIFTAAATNFLQGQSGEQPSLEDIEALPNIHGIYFDEDEWREPWVRGNKILHIELRRWADIMVIAPLSANELAKIAQGWSDNLLLSVVRAWDTTGLIDPVRRIPGVQWPQQEGGIQKKRILVAPSMNTAMWYQPITSKQVRILEEEWGVKNGGWFEVLQPMEKELACGDIGGGAMKDWREIVAVVEERLGLAAQTSETWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2A1</accession>
    <name>W6Z2A1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_99797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689657.1">
        <property type="nucleotide sequence ID" value="XM_007691467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2A1"/>
    <dbReference type="GeneID" id="19129535"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99797"/>
    <dbReference type="HOGENOM" id="CLU_1618846_0_0_1"/>
    <dbReference type="OrthoDB" id="3686819at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="186" mass="21115" checksum="CBF1EFE480006B46" modified="2014-04-16" version="1">MWHNTKTRPVRLNSKVRPLRTTICGFVCSVLGQRLPSTTTRHSRPSKSARLANRRVLVKAIQLLPTHSPTYRAPLCLPQPLTCMSMPSKACYKLPPAIRELLQQRFSSSFCMNMLCPPTLHHHHHHQLYQCVILRLSRSGTNIQTTRFISGQLLCRLVQDEIAEVCLGRVLGMPCMLILTLTPMLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2N1</accession>
    <name>W6Z2N1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964014">
        <property type="protein sequence ID" value="EUC43988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689483.1">
        <property type="nucleotide sequence ID" value="XM_007691293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2N1"/>
    <dbReference type="STRING" id="930090.W6Z2N1"/>
    <dbReference type="GeneID" id="19123398"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38114"/>
    <dbReference type="eggNOG" id="ENOG502SMU2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_7_4_1"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="49"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="487" mass="55307" checksum="EE9C15F9C1ADDD8F" modified="2014-04-16" version="1">MASTSLYQPLDPTREEFRLLRIHPTNIPESIISCQLFTASLAEEPLDITKPIIVNGVRVQVTPNLEAALRRIRPSDSEVTLWVDAVCINQQDLDERNVQVAMMSKLYSKTMLTYAWLGEDDDGSAERVFSFIRGFVGDFTNRVKDIDHFTTKFGKGQCDNMYFGLRDYIAQNLRDGKSALGVSGVLDMRLVFSRSYWYRTWIHQELFLPSKVSMLSGSVSISFNMMIVLGDIIIVQFSTPNQATGALLDFVVSNITMSYPTGTTFLQALCCNILGYRSVDDFQYRVSMYDIRTFLHWILDYGKEKPMLYGRFPAFVDQNNVMAVFEFVPDEISMSLRFAAVTGALDHLVEPYKDAKDHSAFLSITPQQRMAPFWGSESYPDAFQADIEWKIPSECVNLETMRRRTRDWADRKILIVTEKGYIGFATRGVSVGDDVCIVAGCPYPTIIRPSGSHYQVIGGGFIFEMMDGELFRDGHLTNDSQQTFEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2N6</accession>
    <name>W6Z2N6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_38118</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964014">
        <property type="protein sequence ID" value="EUC43993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689485.1">
        <property type="nucleotide sequence ID" value="XM_007691295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2N6"/>
    <dbReference type="STRING" id="930090.W6Z2N6"/>
    <dbReference type="GeneID" id="19123400"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38118"/>
    <dbReference type="eggNOG" id="ENOG502S175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106783_0_0_1"/>
    <dbReference type="OrthoDB" id="3892274at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="119"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="132"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC43993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="226" mass="25555" checksum="0FF7D488BB3CFBBD" modified="2014-04-16" version="1">MDSHSFDYWMAQSNYVVPPHQTTVFDMPPELSKVPSLSGSPVSSTYDQFPAQIQHAYYPQIVDEPVQFGSYPMPMTPSDFGSDHDSPYCSPRPLQHVEPTFGAVHTPAPAERTHTTSGRRRAQNRAAQRAFRERKEKHARDLENQLSILNEKYSKLEVSHSELNAAYEKLRKTIELLTQDDDAEGEDEDGTSTRRCSTNSDTLRKLLEILHGEFKSTTPVKTEAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2X3</accession>
    <name>W6Z2X3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">6-phosphogluconolactonase</fullName>
            <shortName evidence="6">6PGL</shortName>
            <ecNumber evidence="4 6">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_36189</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="4 6"/>
    <dbReference type="EMBL" id="KI963971">
        <property type="protein sequence ID" value="EUC46102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687341.1">
        <property type="nucleotide sequence ID" value="XM_007689151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2X3"/>
    <dbReference type="STRING" id="930090.W6Z2X3"/>
    <dbReference type="GeneID" id="19122968"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36189"/>
    <dbReference type="eggNOG" id="KOG3147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053947_0_1_1"/>
    <dbReference type="OrthoDB" id="432544at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000005">
        <property type="entry name" value="6-phosphogluconolactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="6PGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054:SF0">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="7">
        <location>
            <begin position="12"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="262" mass="28913" checksum="0087A1E0017CACFE" modified="2014-04-16" version="1">MGKPPNLYAFQSTAELAPSLRAYVLDAQNAALDRHHVFRVAVSGGSLPKTLAQALLKETNGEGKIQFDKWEIFYADERAVPLDHEDSNHRLVKEELLDKIPQELGTPKVYPIDVKYLDDVQELADQYEKTLVSVFAARDSVKLPLFDLLLLGCGPDGHTCSLFPGSDLLRETEAWVLPISDSPKPPPKRITISLPVAQHGLKIAFVATGGGKKDIMRQIFDTDEGQQLPCGLVNHKGGERVSWFVDYPAIEGVSFPARRGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z378</accession>
    <name>W6Z378_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">catechol O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_37769</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.6" evidence="1"/>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689082.1">
        <property type="nucleotide sequence ID" value="XM_007690892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z378"/>
    <dbReference type="STRING" id="930090.W6Z378"/>
    <dbReference type="GeneID" id="19123321"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37769"/>
    <dbReference type="eggNOG" id="KOG1663">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050461_0_0_1"/>
    <dbReference type="OrthoDB" id="186626at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006584">
        <property type="term" value="P:catecholamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836:SF2">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0128">Catecholamine metabolism</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="273" mass="28884" checksum="303E912DFC7177B4" modified="2014-04-16" version="1">MAAVLPANTATPVGGTSKYFDTDTLVDGSAPKVANSAGFFNATVAANHNQGAEELALLKYVYSHPDLEQIRGNPDAVCNAIDDFAATIPRGLMTIGAEKREFITKLLTTAEPAPTLFLEFGSYVGYSAICLASAMVARAGPGQRVRYPVAASLADLAGLRDIVTIYVGSASESLARLVKEGKVSKSTVDFMLLDHWKDFYISDLQLCEKLSLLKPGSVVLADNIVFPGAPEYLAYVQAGKAEASPDGFSYTTKTADFILPFGGPDQLAISTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3I3</accession>
    <name>W6Z3I3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_98527</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964007">
        <property type="protein sequence ID" value="EUC44288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689197.1">
        <property type="nucleotide sequence ID" value="XM_007691007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3I3"/>
    <dbReference type="GeneID" id="19129282"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98527"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:001516">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF49">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="45"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="483" mass="53038" checksum="4003BD512954A8AE" modified="2014-04-16" version="1">MAVHHDAEKHGEVSDKYTDIQNIDAIEETNAPAVRALIWKQDLRIIPLCATIYLLCFLDRSNIGNAKTLNANEGHSLLQETHMTNYQFTIALMVFLVAYAVFEVPSNYFLKKFKPSRWIAFLMFGWGACTIGLGGAKNYATVTAVRFLLGACEAGLFPGLVYYLTFWYRARERSIRVAIILASATLAGAFGGAIAYGVGHMKMVHGLSAWRWLFILEGIPSCVSSVAVWLLLPDYPEEASWLSTSERELAVARLENEGSKGNAPSLTWKTAKETLLDGRLWVHYIIYFGISAPFSSLSLFTPTITAGLGYENLQAQLMTVPPYAVAYVVSIVTAWSSDYFNARALHAAALSTIGAIGFLASALLPADAFHARYGCLIIAASGAFSCIPPLLGWLSTNMHSTAATGLAIALNVSWGAPGQIVGVWIYKANEKKAGYPTGHWTNFAMLMMVAVGCIGLRFYYQWCNKRMRQLGTDGTNAMREFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z400</accession>
    <name>W6Z400_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_98149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964004">
        <property type="protein sequence ID" value="EUC44463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689058.1">
        <property type="nucleotide sequence ID" value="XM_007690868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z400"/>
    <dbReference type="GeneID" id="19129201"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98149"/>
    <dbReference type="HOGENOM" id="CLU_2605676_0_0_1"/>
    <dbReference type="OrthoDB" id="3681517at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="84" mass="9879" checksum="8EEAD5E77485242D" modified="2014-04-16" version="1">MLVNRILVVSTRRHLEVLPQDSVQTGWAEKGTRGLFGYLLSSYMLDYYWSRFYLLLTRADRHSLCDWESNILKIAVPMLQPLEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4T2</accession>
    <name>W6Z4T2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_103055</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964055">
        <property type="protein sequence ID" value="EUC42614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690884.1">
        <property type="nucleotide sequence ID" value="XM_007692694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4T2"/>
    <dbReference type="GeneID" id="19118212"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103055"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="OrthoDB" id="1669814at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF83">
        <property type="entry name" value="(3R)-3-HYDROXYACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC42614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="252" mass="26524" checksum="CDDEEECDB73B6E85" modified="2014-04-16" version="1">MAKEFEGKVALITGAGSGIGRATALKLSSLGASISLCDINQSNLEVVASESSTPCYTQKVNVSKKEEVESFVNNTVKQLGGLNYVFNCAGVNPTSMKVEDTSEEYWDKLVNTNLKGVFLVTQACLPHLERGSAIVNVSSISGIRGSALQSVYCTTKFGLIGMSKSHALEFGPRGIRVNCVAPGYIDTPSNAGIVKGGEAVERMRNGNALERLGTPEEVADVVAFLFGDGARYVNGAVVEIDGAVKMSSTTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4V5</accession>
    <name>W6Z4V5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_5909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688660.1">
        <property type="nucleotide sequence ID" value="XM_007690470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4V5"/>
    <dbReference type="STRING" id="930090.W6Z4V5"/>
    <dbReference type="GeneID" id="19124774"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5909"/>
    <dbReference type="eggNOG" id="KOG3007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042088_0_1_1"/>
    <dbReference type="OrthoDB" id="41492at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="entry name" value="ornithine cyclodeaminase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812:SF19">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="38695" checksum="2A332C0F375485BD" modified="2014-04-16" version="1">MVFTVLSDADIRSLLCNLDPADAENLTSQLNQALSQYSCNDEAPYQPHRAQVTRPDGQVSLFMPATTPSSIGVKIVGVAPSQTPPPGEKPKPALKSVLTICDELGQAVGVLNAAELTAFRTALGTMLLYRYRKSTQNIVVFGAGKQAEWHIRLALLLKSNDISKITIVNRSRARADQLVGSLTRAGLSSHIQIKVFEGDEEPLKSLVKESHVIFCTTPSTTPLFPASYLASEADKPRFISAIGSYRLDMQEIDPDLLSQITSPSGLFASQVHNACIAVDSIKGCMDEAGELVKADIATERMIEVGKIDGLRQDDGVKRWLEQGLVVYKSVGVGVMDIAIGKALLELSGEKGVGVRVDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z672</accession>
    <name>W6Z672_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3'(2'),5'-bisphosphate nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_101884</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964041">
        <property type="protein sequence ID" value="EUC43059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690443.1">
        <property type="nucleotide sequence ID" value="XM_007692253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z672"/>
    <dbReference type="STRING" id="930090.W6Z672"/>
    <dbReference type="GeneID" id="19117956"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101884"/>
    <dbReference type="eggNOG" id="KOG1528">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033446_1_0_1"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF2">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC43059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="42097" checksum="68D39EDAB716DAE4" modified="2014-04-16" version="1">MAYTAELRLALRAVHRASVLTKSVLRSLSNNVSAETKADDSPVTIADFAAQALLISALHAAYPHDAFLGEESADALRQNEALADRVWQLVQQAKEEADARLDANGKDQEATASTAAAAAAAHDLNEDPVLAFPASKEDMFDLIDRGGNGQVTGLGRVWVMDPVDGTATFMRGQQYAVCLCLLVDGVQQVGVIACPNLAFPLQGTLGSIHISEDNVDSDGYGVVLSAVKGQGTFLRTMEASGPGAHARHVDLTTLPPKQTSDLNFVEATIGKTSLSQTEHEAVATALSASWPGTVLWSQQMKYVALTLGATDVMVRIPKTLDRFTCIWDHAGGHLLFQEAGGIISDFRGEQIDFSAGRKIKGERNWGMIACMPAVFEQVGTAVKHVLNQRDADQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6J7</accession>
    <name>W6Z6J7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_36815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963984">
        <property type="protein sequence ID" value="EUC45433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688031.1">
        <property type="nucleotide sequence ID" value="XM_007689841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6J7"/>
    <dbReference type="GeneID" id="19123117"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36815"/>
    <dbReference type="eggNOG" id="ENOG502TFYI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2498611_0_0_1"/>
    <dbReference type="OrthoDB" id="4159814at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="102" mass="10924" checksum="12761223021C7C17" modified="2014-04-16" version="1">MLPYTSAAPLIKRDEGYLLPKPVIILLIIIGAGLLVCVGFAVHSAFGFRSNGNGMKNMGSEQMEYMTAVRGRNLAVMMAQGQRSRMEGAGPGGVRMGESVYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7G4</accession>
    <name>W6Z7G4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleotide exchange factor Fes1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_36595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FES1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687775.1">
        <property type="nucleotide sequence ID" value="XM_007689585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7G4"/>
    <dbReference type="STRING" id="930090.W6Z7G4"/>
    <dbReference type="GeneID" id="19123066"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36595"/>
    <dbReference type="eggNOG" id="KOG2160">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084507_0_0_1"/>
    <dbReference type="OrthoDB" id="10250458at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071629">
        <property type="term" value="P:cytoplasm protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000434">
        <property type="entry name" value="Hsp70 nucleotide exchange factor fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013918">
        <property type="entry name" value="Nucleotide_exch_fac_Fes1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08609">
        <property type="entry name" value="Fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Nucleotide exchange factor Fes1" evidence="7">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="210" mass="23361" checksum="9C609C05A026103B" modified="2014-04-16" version="1">MNDPGLNNLLKWGIQNSEASRTDGAAADQRPAQIDVEALQRLVTGMSGPSDAQLMQESMQVIQNEEAELEHRTTAFDNFEQLIENLDNANNIESLGLWMPLVQQLENKESELRFYAAWCCGTAVQNNIRTQERLLVVGAIPTLVRMATSDADKKVRKKAIFALSSSVRNFQAGLDAALEHVPAELKPKEKLDANDMESVDLLINKLRDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7Z3</accession>
    <name>W6Z7Z3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_41753</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964246">
        <property type="protein sequence ID" value="EUC39811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693670.1">
        <property type="nucleotide sequence ID" value="XM_007695480.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z7Z3"/>
    <dbReference type="GeneID" id="19124129"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41753"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901336">
        <property type="term" value="P:lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF50">
        <property type="entry name" value="HIGHLY REDUCING POLYKETIDE SYNTHASE SRDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="4"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="11">
        <location>
            <begin position="863"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2174"/>
            <end position="2252"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="863"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1011"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="895"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1075"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC39811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="2254" mass="246296" checksum="9620CFAC66285475" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z846</accession>
    <name>W6Z846_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_88850</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685625.1">
        <property type="nucleotide sequence ID" value="XM_007687435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z846"/>
    <dbReference type="STRING" id="930090.W6Z846"/>
    <dbReference type="GeneID" id="19127357"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88850"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_1_0_1"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000005">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000095">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="11">
        <location>
            <begin position="8"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC47902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="398" mass="43677" checksum="34FE27ABECD84F47" modified="2014-04-16" version="1">MNSAPSGYKNVAYFVNWAIYGRNHHPQDLPAEELTHVLYAFADVRDTGEVFLTDSWSDTDKHYANDSWNDVGNNVYGCVKQLFLQKKRNRKLKVLLSIGGWTYSSHFATPASTAQGRAKFASSAVALLANLGFDGLDVDWEYPANDSQANDMVLLLQETRRALTAYSNENANGQHLLLTIASPAGPKNYNIMKLAQMDQYLDFWNLMAYDYAGSWDTTSGHLANWAPSVSNSNSTPFSTTAAINDYVAAGVPASKIVLGMPLYGRSFANTDGPGKPYQGVGQGTWETGVYDYKVLPQAGAQVYTDNQITASWSYDSNSRLMISYDTPEIIAKKTQLIRDNGLGGGMWWESSSDKKGSDSLVSTFVNNIGGISALDQSTNLLSFPTSKYDNLRAGFPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8D2</accession>
    <name>W6Z8D2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component SEC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_93839</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the exocyst complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SEC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963972">
        <property type="protein sequence ID" value="EUC46048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687416.1">
        <property type="nucleotide sequence ID" value="XM_007689226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8D2"/>
    <dbReference type="STRING" id="930090.W6Z8D2"/>
    <dbReference type="GeneID" id="19128338"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93839"/>
    <dbReference type="eggNOG" id="KOG2347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011308_0_0_1"/>
    <dbReference type="OrthoDB" id="26242at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029175">
        <property type="entry name" value="EXOC2/Sec5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039481">
        <property type="entry name" value="EXOC2/Sec5_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15469">
        <property type="entry name" value="Sec5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC2/Sec5 N-terminal" evidence="6">
        <location>
            <begin position="87"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="187"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="516"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="572"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="573"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1060" mass="118702" checksum="F8E07FC5C3229787" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8W7</accession>
    <name>W6Z8W7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor TFIID subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_92911</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a component of both the DNA-binding general transcription initiation factor complex TFIID and the transcription coactivator SAGA complex. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription. SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription. At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B. SAGA interacts with DNA via upstream activating sequences (UASs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TAF10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687068.1">
        <property type="nucleotide sequence ID" value="XM_007688878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8W7"/>
    <dbReference type="STRING" id="930090.W6Z8W7"/>
    <dbReference type="GeneID" id="19128170"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92911"/>
    <dbReference type="eggNOG" id="KOG3423">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064104_0_1_1"/>
    <dbReference type="OrthoDB" id="154356at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990841">
        <property type="term" value="F:promoter-specific chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07982">
        <property type="entry name" value="HFD_TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003923">
        <property type="entry name" value="TAF10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03540">
        <property type="entry name" value="TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017246">
        <property type="entry name" value="TFIID_TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="139"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="222" mass="23383" checksum="CEEB9D1D427BBAFF" modified="2014-04-16" version="1">MSENNSQPLDTNMEVNDELDRTVDEEIKQDATQLEADAMNLDGANDTEPSAMNGAADPVASFEARIPAKKDATLREFLGKMDEYAPIIPDAVTNYYLTRAGLPPPPQTSQHLARLLALATQKFIADIAADAYQFSRIRSSNTTSNNPMGGAGGPPGAAAPGGVPGGKDSGAKAKDYNLGIQRPGYGGGGQGGSQGRTVLTMEDLGMAVGEYGVNIKRGEFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9Q1</accession>
    <name>W6Z9Q1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Concentrative nucleoside transporter C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_92144</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686793.1">
        <property type="nucleotide sequence ID" value="XM_007688603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9Q1"/>
    <dbReference type="STRING" id="930090.W6Z9Q1"/>
    <dbReference type="GeneID" id="19128020"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92144"/>
    <dbReference type="eggNOG" id="KOG3747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016813_1_1_1"/>
    <dbReference type="OrthoDB" id="6075923at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="618"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="9">
        <location>
            <begin position="236"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="11">
        <location>
            <begin position="317"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="10">
        <location>
            <begin position="421"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC46715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="651" mass="71800" checksum="7D9C407272DE03B0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9R2</accession>
    <name>W6Z9R2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">SSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_2555</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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    <sequence length="1271" mass="140294" checksum="77E341FF23F95307" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Han J."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_24984"/>
    <dbReference type="HOGENOM" id="CLU_1758496_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC47065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="148" mass="16229" checksum="FE58EE2A635DFBB0" modified="2014-04-16" version="1">MPTTVAIDVVQNTHFQLTPPNIGPRAGPKSSAAMYTANTLPLSLPHPVFQIRNTALPLNKTGLRQYTSSKGAKMSGSKLMPTRTRELQGIHLQGLVIYKSPETWGSRGTSMVSVSAWRDNKDEGISAAVHLWARGQFLWGLMVHDMSM</sequence>
</entry>
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    <accession>W6ZAW4</accession>
    <name>W6ZAW4_COCMI</name>
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        </submittedName>
    </protein>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAW4"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_40870"/>
    <dbReference type="HOGENOM" id="CLU_1731139_0_0_1"/>
    <dbReference type="OrthoDB" id="3692737at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="137" mass="15090" checksum="AF35DC4EE11F7D35" modified="2014-04-16" version="1">MTGALLAIIGNGIVALLDFGQRLKGYLEHQPGFLGQSIPLVVPFVGDILVAGMTHCRISIMYEWTVQSMNFACIGLCASASAIGQHFFEFFEYFDHPSWIGLPRHAVISAQVVASTSWKDYILDFGWSGEDITLYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB55</accession>
    <name>W6ZB55_COCMI</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">COCMIDRAFT_24941</name>
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            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="19120666"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="128" mass="14304" checksum="EE45F7A0C389420A" modified="2014-04-16" version="1">MRIVALTCNDVIGNMSEQARIGTTTPPQSTHWNKRVFWTQPRLARDFVVYCIQQRHASLQPKGLGRARCKWNSLAASGQQRSARCEGSIRVARRDAEELGLTLQSGRLQCNSTVMLCTSYSTGTQHVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBU3</accession>
    <name>W6ZBU3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_37346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBU3"/>
    <dbReference type="GeneID" id="19123230"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37346"/>
    <dbReference type="HOGENOM" id="CLU_2903873_0_0_1"/>
    <dbReference type="OrthoDB" id="3658492at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="62" mass="7217" checksum="91F3A6ED98F92B3C" modified="2014-04-16" version="1">MFACLMKCVMMGYVGFKISIKLWAGPWPDASWKWNYKFKGSKETEATYKAIWTSLRQIFLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCE0</accession>
    <name>W6ZCE0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PWI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_89556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007687680.1"/>
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    <dbReference type="STRING" id="930090.W6ZCE0"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_89556"/>
    <dbReference type="eggNOG" id="KOG2146">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073353_0_0_1"/>
    <dbReference type="OrthoDB" id="163257at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052225">
        <property type="entry name" value="Ser/Arg_repetitive_matrix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148">
        <property type="entry name" value="SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148:SF0">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWI" evidence="3">
        <location>
            <begin position="12"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="328" mass="36615" checksum="961C5927D4189EF7" modified="2014-04-16" version="1">MALSIDQKRLKATKFPPEFDKKVDIEKVNIDLMKRWIANKITTILGDEDDIVVETCYNLVEQSQFPKIKEIQIQLTGFLGKDTAPFCKELWDLMLSAQDSPVGVPRELLEAKKAELQQEQLSKAAADARRAEDQAQNAMIDSFRQSERSDRPERGRGGGGRYRGSDREEGIPHRIASATYTYLEEAEVAVVEGVTIGHASAVVPLQAVVLHPHHLVVHVAHHRQDHREVHPGAELVARHRLIALGLRLAARDGDPLQEAILRPRDDEGHARTGLGLLAKIREGYLGIIRDLVLLVVNRAHQRPGSERGHHHKALHAVDVALLRGLLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCM7</accession>
    <name>W6ZCM7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_89746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685956.1">
        <property type="nucleotide sequence ID" value="XM_007687766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCM7"/>
    <dbReference type="STRING" id="930090.W6ZCM7"/>
    <dbReference type="GeneID" id="19127540"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89746"/>
    <dbReference type="eggNOG" id="ENOG502SSWY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1001110_0_0_1"/>
    <dbReference type="OrthoDB" id="5313288at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="278" mass="31609" checksum="16CCE388F3956660" modified="2014-04-16" version="1">MPSLDSLPPELLFHILSYTSPPNCLTLPIYPLNALAATNRHLHAIVEEYARNLLKRHAGMELPKNARVSSCRRKWLGEICWFCKRKSRRKACFGRGMTCCLGCDRREFAKMTMTQATQQTHLSKFDLFTPSPLHPNLPPLATGSYPVMGDVATMISTPDVMARSAHIRSLLGEKAQDETFMRKRAAAHARIMKHMNMDYHQGKGWLAYREMTKKGPKSMQTEEGRRKYIEEGLRKEWEALGVEPYEHVLARVNGQLMKWVIPPEGDGRGGSRESAIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD27</accession>
    <name>W6ZD27_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inner kinetochore subunit AME1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_3343</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685730.1">
        <property type="nucleotide sequence ID" value="XM_007687540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD27"/>
    <dbReference type="GeneID" id="19122328"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3343"/>
    <dbReference type="eggNOG" id="ENOG502SGUR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028282_0_0_1"/>
    <dbReference type="OrthoDB" id="5377952at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048743">
        <property type="entry name" value="AME1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20994">
        <property type="entry name" value="CENPU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inner kinetochore subunit AME1" evidence="3">
        <location>
            <begin position="494"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="547"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="180"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="426"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="691" mass="75241" checksum="E218CF549ABCEAFB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD77</accession>
    <name>W6ZD77_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">allantoinase</fullName>
            <ecNumber evidence="6">3.5.2.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_88589</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-allantoin + H2O = allantoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17029"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15678"/>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
            <dbReference type="EC" id="3.5.2.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.5" evidence="6"/>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685508.1">
        <property type="nucleotide sequence ID" value="XM_007687318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD77"/>
    <dbReference type="STRING" id="930090.W6ZD77"/>
    <dbReference type="GeneID" id="19127308"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88589"/>
    <dbReference type="eggNOG" id="KOG2584">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015572_4_0_1"/>
    <dbReference type="OrthoDB" id="10258955at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004038">
        <property type="term" value="F:allantoinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009442">
        <property type="term" value="P:allantoin assimilation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000032">
        <property type="entry name" value="Allantoinase Dal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050138">
        <property type="entry name" value="DHOase/Allantoinase_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668:SF2">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="10">
        <location>
            <begin position="74"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="522" mass="56197" checksum="45EA3C1F1643750A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDF5</accession>
    <name>W6ZDF5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 36 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_88862</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-galactosyl-(1-&gt;3)-1D-myo-inositol + sucrose = raffinose + myo-inositol</text>
            <dbReference type="Rhea" id="RHEA:20161"/>
            <dbReference type="ChEBI" id="CHEBI:16634"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:17505"/>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
            <dbReference type="EC" id="2.4.1.82"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolases 36 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685604.1">
        <property type="nucleotide sequence ID" value="XM_007687414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDF5"/>
    <dbReference type="GeneID" id="19127361"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88862"/>
    <dbReference type="eggNOG" id="ENOG502QPVE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006630_0_0_1"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047274">
        <property type="term" value="F:galactinol-sucrose galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000222">
        <property type="entry name" value="Raffinose synthase Sip1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008811">
        <property type="entry name" value="Glycosyl_hydrolases_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268:SF32">
        <property type="entry name" value="GALACTINOL--SUCROSE GALACTOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05691">
        <property type="entry name" value="Raffinose_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="838" mass="92927" checksum="B7BFD38002D3E657" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEM1</accession>
    <name>W6ZEM1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_87436</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685086.1">
        <property type="nucleotide sequence ID" value="XM_007686896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEM1"/>
    <dbReference type="GeneID" id="19127056"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87436"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="520"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC48465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="61970" checksum="B62FBA99348E1AE7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFN8</accession>
    <name>W6ZFN8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_802</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682813.1">
        <property type="nucleotide sequence ID" value="XM_007684623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFN8"/>
    <dbReference type="GeneID" id="19125624"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_802"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_16_0_1"/>
    <dbReference type="OrthoDB" id="3233595at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
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        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF5">
        <property type="entry name" value="OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="9"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="335" mass="35888" checksum="192BC73DA32FC666" modified="2014-04-16" version="1">MKEAQVSKGTVVVIKDVEIPQPGPKQVVIKVIVSGTNPKDWKLPELGMQNDANTGDDIAGYVHSVGSEVYEFKPGDRVASFHEMMTPGGSFAEYAVGWQHTTFHIPKSVSFEEAATIPLAAMTSAIGLQVRLGLPDPWTPVPDGKKLPLVVYSGASAVGAFAIKIAHKANIHPIIAVAGRGTSYVETLLDRSKGDTIIDYRSGDDAVVNGIRDALQGEKLHYAFDAVSEHGSYNNIAKVLDPSGAIALVLPAKEKEGIPETVTLTMTMVGSAHAQDADFAHVMFRWMARGLQEGWFKGHPFEVVPGGLAGVETGLRNLKEGKASAVKYVYKIGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG40</accession>
    <name>W6ZG40_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_35841</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686959.1">
        <property type="nucleotide sequence ID" value="XM_007688769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG40"/>
    <dbReference type="GeneID" id="19122881"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35841"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000364">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF54">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="65"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="520" mass="57953" checksum="F89CC8F9C0FD2258" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGD6</accession>
    <name>W6ZGD6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_92490</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686908.1">
        <property type="nucleotide sequence ID" value="XM_007688718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGD6"/>
    <dbReference type="STRING" id="930090.W6ZGD6"/>
    <dbReference type="GeneID" id="19128088"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92490"/>
    <dbReference type="eggNOG" id="KOG0737">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004223_1_1_1"/>
    <dbReference type="OrthoDB" id="39734at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056027">
        <property type="entry name" value="DUF7608"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051701">
        <property type="entry name" value="Mito_OM_Translocase_MSP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644:SF56">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24581">
        <property type="entry name" value="DUF7608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="902"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="40"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1097"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1207" mass="131932" checksum="3FE8AE59009D5983" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGG9</accession>
    <name>W6ZGG9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I and III subunit RPAC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_80762</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682595.1">
        <property type="nucleotide sequence ID" value="XM_007684405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGG9"/>
    <dbReference type="STRING" id="930090.W6ZGG9"/>
    <dbReference type="GeneID" id="19125730"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80762"/>
    <dbReference type="eggNOG" id="KOG1521">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038421_0_1_1"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055029">
        <property type="term" value="C:nuclear DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07032">
        <property type="entry name" value="RNAP_I_II_AC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000003">
        <property type="entry name" value="Dna-directed rna polymerases i and iii subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033901">
        <property type="entry name" value="RNAPI/III_AC40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF13">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="7">
        <location>
            <begin position="61"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="376" mass="42736" checksum="E20F8AD394AF957A" modified="2014-04-16" version="1">MSKPSAQELMKRKTLQVGPETVMNQQSTDFPGHWPGENHEWDLDYFKENFNVTFHSHSPFDTQFSLTGIDTSVANAFRRILLSEIPTLAIEDVFIYQNTSIIQDEVLAHRLGLVPLCGDREGLRAMKWYSKPTEEDPESGTPTDWNTVVLRLDVECKWQEGGLQRAVAGETDPDKLYIGHNVYAKDIEFKPIGRQAELFSSEQGKEIRSTNPDILIAKMRPGQSINLSMHAIKGIGQDHAKFSPVATASYRLMPTIDITKPIVGPDAKKFARCFPRGVIRLDTVTETDVKQHPELEGKEGEAKAVVANAMNDTVSRECLRHPEFKDKVRLGRIRDHFIFRVESTGQWESDELFLESIKLLKIKCQRIKRGLEEMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGY2</accession>
    <name>W6ZGY2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_92088</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686778.1">
        <property type="nucleotide sequence ID" value="XM_007688588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGY2"/>
    <dbReference type="STRING" id="930090.W6ZGY2"/>
    <dbReference type="GeneID" id="19128007"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92088"/>
    <dbReference type="eggNOG" id="KOG4628">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132739_0_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16473">
        <property type="entry name" value="RING-H2_RNF103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45969:SF81">
        <property type="entry name" value="OS08G0157400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45969">
        <property type="entry name" value="RING ZINC FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="100"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="170" mass="19015" checksum="7E8493AA06788209" modified="2014-04-16" version="1">MSSNSTETKEPSGPRGGTLVIAIIVPSVLIILLVVLIIVNRRRGFLLPRLAREERRVRENGWKTRKEELESRVKAQCFSEWVTGQKEKGSGAPQMSDALCAICLDDFADDSQVRGLECAHAFHSHCLDEWYTKYNEYCPLCHGPIIPGARLAKKKAREVGEPTIPVILMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHB9</accession>
    <name>W6ZHB9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_63</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682055.1">
        <property type="nucleotide sequence ID" value="XM_007683865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHB9"/>
    <dbReference type="GeneID" id="19124913"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_63"/>
    <dbReference type="HOGENOM" id="CLU_2096648_0_0_1"/>
    <dbReference type="OrthoDB" id="3694712at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890019" evidence="2">
        <location>
            <begin position="19"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="116" mass="12318" checksum="ACF3D5E8A99A3596" modified="2014-04-16" version="1">MKFILPTILLLLATLTTATPSSPFTGASIQQCNEALTARAAHAYTDAHPQLAARSSNNNNKKKKGKKTKKPKGGHLGSNNDTETESAAMMRFVPPMGALQVGVVGFGVLEVVRLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHC7</accession>
    <name>W6ZHC7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="11">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_35557</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="11"/>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686630.1">
        <property type="nucleotide sequence ID" value="XM_007688440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHC7"/>
    <dbReference type="STRING" id="930090.W6ZHC7"/>
    <dbReference type="GeneID" id="19122809"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35557"/>
    <dbReference type="eggNOG" id="KOG0975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031922_0_0_1"/>
    <dbReference type="OrthoDB" id="1732691at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000012">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF69">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC46824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="447" mass="49038" checksum="12EA4A6F9E2FF150" modified="2014-04-16" version="1">MAPIAVTPPNQNENVTDLTQEGIKSALLKNAPGQINSSSLTNSITATPPNEPASKTQDVVEAPLAELDASKITCTFTNSPCSVPAVGSAEMASQKVCTDHMVQAKWTVESGWEAPTLQPYGPISLAPTASCLHYATECFEGMKLYRGHDGKLRLFRPDLNCRRMLMSTNRIALPAFDPQELLKLIVKLCATDGKRWLPKDRPGQFLYIRPTMIASDPALGVERPKEALLFVILCCFAPMGDMNGGIKLLASQDDMCRAWPGGFGYAKVGANYGPSLVAQGEARKRGYHQILWLFGEDCTITEAGASNFFVIWRTKEGKLQLVTADLNERIVLDGVTRRSILELARAKLVSDAPQDLETLEVVERKFNIFEIEEAAKEGRLVEAFAAGTAWFVAPISQIHFRGKDMDVPMAKGNSGAYAEFFKSSLKGIMWGCDGMESHEWGRVIDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHP5</accession>
    <name>W6ZHP5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_101806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964040">
        <property type="protein sequence ID" value="EUC43076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690397.1">
        <property type="nucleotide sequence ID" value="XM_007692207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHP5"/>
    <dbReference type="GeneID" id="19117939"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101806"/>
    <dbReference type="HOGENOM" id="CLU_3087068_0_0_1"/>
    <dbReference type="OrthoDB" id="3665968at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="52" mass="5975" checksum="8989D765B39AF189" modified="2014-04-16" version="1">MCLIWACMDQRFHYLPISLWGSLSGPRPYLILTPQTHQTKGCALLLKQCIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHV2</accession>
    <name>W6ZHV2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_1767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0235 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683947.1">
        <property type="nucleotide sequence ID" value="XM_007685757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHV2"/>
    <dbReference type="STRING" id="930090.W6ZHV2"/>
    <dbReference type="GeneID" id="19119943"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1767"/>
    <dbReference type="eggNOG" id="KOG3276">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130694_1_0_1"/>
    <dbReference type="OrthoDB" id="244097at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="entry name" value="YggU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00634">
        <property type="entry name" value="UPF0235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00251">
        <property type="entry name" value="DUF167 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13420">
        <property type="entry name" value="UPF0235 PROTEIN C15ORF40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13420:SF7">
        <property type="entry name" value="UPF0235 PROTEIN C15ORF40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="YggU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="118" mass="12547" checksum="6FA7BE16CD5F0330" modified="2014-04-16" version="1">MSGQAIRFVAAVAARPSTGTIQLLCHVKPGVSASREGIAAVSDERIHLCVAAQARDGEANKAVRRVVADALGVPKSDVEVIKGMKSRDKTVAVRTSLLQAPEEQVERTKLMLQRSSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI22</accession>
    <name>W6ZI22_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_84058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683929.1">
        <property type="nucleotide sequence ID" value="XM_007685739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI22"/>
    <dbReference type="GeneID" id="19126386"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84058"/>
    <dbReference type="eggNOG" id="ENOG502SQ0A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1741824_0_0_1"/>
    <dbReference type="OrthoDB" id="3923202at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="144" mass="15138" checksum="9F79E7C14BB1B666" modified="2014-04-16" version="1">MSCPVIGTTNDHLPPNHPSVDLSKDGQTCPVVGATTDHHHNLHAHPPVPTNETSATACPALKNNIIKQPRAQEMDDALCPIVGVATTVLPPDHPDMLKANEGDICPVTKATVGHHKDKVVTHPSVEAARDGAVCPVTGQKQQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI57</accession>
    <name>W6ZI57_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonucleases P/MRP subunit Pop8-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_38863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964037">
        <property type="protein sequence ID" value="EUC43191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690301.1">
        <property type="nucleotide sequence ID" value="XM_007692111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI57"/>
    <dbReference type="STRING" id="930090.W6ZI57"/>
    <dbReference type="GeneID" id="19123568"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38863"/>
    <dbReference type="eggNOG" id="ENOG502SCWV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115053_1_0_1"/>
    <dbReference type="OrthoDB" id="5530243at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000171">
        <property type="term" value="F:ribonuclease MRP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034965">
        <property type="term" value="P:intronic box C/D snoRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000294">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, RNase MRP-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020347">
        <property type="entry name" value="Pop8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049128">
        <property type="entry name" value="Pop8-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28173">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28173:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20976">
        <property type="entry name" value="Pop8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonucleases P/MRP subunit Pop8-like" evidence="2">
        <location>
            <begin position="55"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="178" mass="18401" checksum="279828B91E984744" modified="2014-04-16" version="1">MAQDNAPNVAPNNPPAHTDTDADTSMPDAATPKPASKPEKPAHILHQTTLRKPTWSYLHLTLTSPSFPSSTSSASTTTPTTDISPLLISPLLTSALRAYLGTMGAAIPVDILKTAGREVWIRVPRQDVRGVKAALGSWVGRVEGEDVGGEAGRVGVAWRVVGGAGVLGGMGDGGEVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIE5</accession>
    <name>W6ZIE5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Lysophospholipase NTE1</fullName>
            <ecNumber evidence="3 16">3.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Intracellular phospholipase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">COCMIDRAFT_90994</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 16">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the NTE family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="3 16"/>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686360.1">
        <property type="nucleotide sequence ID" value="XM_007688170.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZIE5"/>
    <dbReference type="GeneID" id="19127799"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90994"/>
    <dbReference type="eggNOG" id="KOG2968">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_1_1_1"/>
    <dbReference type="OrthoDB" id="421051at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034638">
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071071">
        <property type="term" value="P:regulation of phospholipid biosynthetic process"/>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Lysophospholipase NTE1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Lysophospholipase NTE1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
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        <property type="entry name" value="cNMP-bd_dom"/>
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        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="LysoPLipase_patatin_CS"/>
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        <property type="entry name" value="NTE1_P-loop_dom"/>
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        <property type="entry name" value="PNPLA_dom"/>
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        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
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        <property type="entry name" value="NEUROPATHY TARGET ESTERASE SWS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NTE_Ploop"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="FabD/lysophospholipase-like"/>
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    </dbReference>
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        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UPF0028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 15 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 15 16" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11 15 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="18">
        <location>
            <begin position="653"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="18">
        <location>
            <begin position="804"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="19">
        <location>
            <begin position="1183"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="239"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="474"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="718"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="15">
        <location>
            <begin position="1187"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="15">
        <location>
            <begin position="1214"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="15">
        <location>
            <begin position="1334"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="480"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
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        <location>
            <position position="1216"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="1334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006636"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00018317"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
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            <dbReference type="ARBA" id="ARBA00024965"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00049531"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1486" mass="164197" checksum="1DC64E06C50D6BF8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIS8</accession>
    <name>W6ZIS8_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_1312</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="104"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="663" mass="75016" checksum="6636C464DA1EC42C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIU5</accession>
    <name>W6ZIU5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Class E vacuolar protein-sorting machinery protein HSE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Class E vacuolar protein-sorting machinery protein hse1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_22484</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the STAM family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIU5"/>
    <dbReference type="STRING" id="930090.W6ZIU5"/>
    <dbReference type="GeneID" id="19120258"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22484"/>
    <dbReference type="eggNOG" id="KOG3417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002632_0_0_1"/>
    <dbReference type="OrthoDB" id="546434at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Unconventional Myosin IB"/>
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    </dbReference>
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        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
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        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
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    </dbReference>
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        <property type="entry name" value="WW_fungi"/>
    </dbReference>
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        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF7783"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00617">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
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        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0967">Endosome</keyword>
    <keyword evidence="8 10" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
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        <location>
            <begin position="10"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="15">
        <location>
            <begin position="728"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="14">
        <location>
            <begin position="897"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="71"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="193"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="440"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="627"/>
            <end position="681"/>
        </location>
    </feature>
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        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
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        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
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            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
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        <location>
            <begin position="440"/>
            <end position="454"/>
        </location>
    </feature>
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        <location>
            <begin position="628"/>
            <end position="644"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009666"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1151" mass="128201" checksum="843AF364CCB013FB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKR4</accession>
    <name>W6ZKR4_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_88445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889912" evidence="2">
        <location>
            <begin position="23"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="76"/>
        </location>
    </feature>
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        <location>
            <begin position="37"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="276" mass="29652" checksum="2921F67251F1FD3E" modified="2014-04-16" version="1">MLSNTLLTTLLLFSAQTTTTLALPTKTHCQCKIVPNTPSSSTSTTTSPYAIDSPSAAHWAPASPSEDDSASPSPYPLASSTICNTLASQLSQFQHTNPDLYALYLQRAPTRSIDDSVAQNPIPTSVLLSATSSDAPSTGANEFKIVCYQDESSPESAMPLRDIQSSPLTLLILQLIVVLSIVACIAEGLHMLKNLISPPPTPSHSLRLAGAEKRLLAIPPTPYDNSLDAMSSPGAEKKLRAYYEAPRYFVAQGKSGRREFIAYDDDSDDEINRPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL79</accession>
    <name>W6ZL79_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_87823</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC48274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685278.1">
        <property type="nucleotide sequence ID" value="XM_007687088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL79"/>
    <dbReference type="STRING" id="930090.W6ZL79"/>
    <dbReference type="GeneID" id="19127135"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87823"/>
    <dbReference type="eggNOG" id="KOG0181">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_4_1_1"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03750">
        <property type="entry name" value="proteasome_alpha_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000048">
        <property type="entry name" value="Proteasome subunit alpha type-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="8">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC48274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="279" mass="30069" checksum="73E49CAE7848D70D" modified="2014-04-16" version="1">MADRYSFSLTTFSPSGKLVQIEYALNAVNQGVTSLGIKATNGIVLATEKKSSSPLIDSQSSSKISLITPNLGMVYSGMGPDYRVLVDKARKVSHTGYKRVYNEYPPTRILVQDVARVMQEATQSGGVRPYGVSLLIAGWDDGIEPEAEGKSDEQTSEEKKKVSGKTGGILKGGPSLYQVDPSGSYFPWKATAIGKSATSAKTFLEKRYTDGLELEDAIHIALLTLKETIEGEMNGETVEIGIVGPPEERLLGVEGVEGAVGPRFRKLSPSEVEDYLTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLR9</accession>
    <name>W6ZLR9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_37623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688936.1">
        <property type="nucleotide sequence ID" value="XM_007690746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLR9"/>
    <dbReference type="GeneID" id="19123289"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37623"/>
    <dbReference type="eggNOG" id="KOG4754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039184_1_2_1"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF24">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="28545" checksum="1F1E0080BA9A23F7" modified="2014-04-16" version="1">MAPKLVLIRHAQAQHNATNDWSIRDPPLTELGEQQCRELHEHLKQTEIGNQIELIVVSAQRRTLQTATIGLDWLIKKGIKVIPDANWQENADKPCDTGTPLDVISKEFPQYDFSVVDPSFPDKTTNGPKNPYAFTEKAIVARGQRCLEDLYSRPEKVIAVVSHSGFLRTAICNRMFFNADYRVFDFDEEAMKKQPGTFVLKESDETEKSGGGMGRSEVGVFGIVPGDFPPEVDEQDVAKEADKVDDEAVREKPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZME9</accession>
    <name>W6ZME9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_62765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682200.1">
        <property type="nucleotide sequence ID" value="XM_007684010.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZME9"/>
    <dbReference type="GeneID" id="19124908"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_62765"/>
    <dbReference type="HOGENOM" id="CLU_1839842_0_0_1"/>
    <dbReference type="OrthoDB" id="3695699at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="140" mass="15567" checksum="517BFBB084DAB254" modified="2014-04-16" version="1" fragment="single">NIYISSEIYHALESTGPIILAITPTAIATSTVAYEKEDKEGNDHEPYPHTTSPPQSKAAKPAWVNPSTAALLCFDFLASTFFVWCWVMGWFSWLRGDQDHASVMGQARGQAYRVGEARDSGMQVLANQNVEQEMRRLGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN27</accession>
    <name>W6ZN27_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_5744</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC44986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688463.1">
        <property type="nucleotide sequence ID" value="XM_007690273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN27"/>
    <dbReference type="STRING" id="930090.W6ZN27"/>
    <dbReference type="GeneID" id="19124724"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5744"/>
    <dbReference type="eggNOG" id="ENOG502SN5U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037979_0_0_1"/>
    <dbReference type="OrthoDB" id="4161589at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="130"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="528" mass="57793" checksum="4869F6FA3B5B24F8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ89</accession>
    <name>W6ZQ89_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_25962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687559.1">
        <property type="nucleotide sequence ID" value="XM_007689369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ89"/>
    <dbReference type="GeneID" id="19120858"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25962"/>
    <dbReference type="HOGENOM" id="CLU_1959748_0_0_1"/>
    <dbReference type="OrthoDB" id="2251794at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889988" description="SH3 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="14122" checksum="A65538D2C8F7CD1B" modified="2014-04-16" version="1">MKFTAFAIATLLPLTALSAPTAEAGGALLFAPEVEGELPVLQDIKARSLEKRAITGTVTADALKHRRCPRTSCTADGQFSRGTRIQIRCFTGTDTTVVSGNPYWGKLQASGVANNNWVSLYYVTWSGGIPEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZS09</accession>
    <name>W6ZS09_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_92681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686975.1">
        <property type="nucleotide sequence ID" value="XM_007688785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZS09"/>
    <dbReference type="GeneID" id="19128120"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92681"/>
    <dbReference type="eggNOG" id="ENOG502R909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129947_0_0_1"/>
    <dbReference type="OrthoDB" id="3793724at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012949275" description="Secreted protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="18627" checksum="880A983B3C7E85ED" modified="2014-04-16" version="1">MRVALLAAILPVALAGWNPKACNGAGGCTHVGFSTPDPYVCPDGSRLNLPSFANENLNAGNGNADSVSKDDFPKTCTSGAVPPADATFIKVKSVNNQTMFFYVTSKCDTPKPEAFNCYNKNPNPSTHTFCSMYDSKGALCKGNPAAGYCERWGYSTVNPQCDFWKPGGPDLPNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZS22</accession>
    <name>W6ZS22_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein kinase MEC1</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">ATR homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">DNA-damage checkpoint kinase MEC1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Mitosis entry checkpoint protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">COCMIDRAFT_1026</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26 27">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683122.1">
        <property type="nucleotide sequence ID" value="XM_007684932.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZS22"/>
    <dbReference type="GeneID" id="19118111"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1026"/>
    <dbReference type="eggNOG" id="KOG0890">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000178_4_1_1"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00892">
        <property type="entry name" value="PIKKc_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000032">
        <property type="entry name" value="Protein kinase rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056802">
        <property type="entry name" value="ATR-like_M-HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058681">
        <property type="entry name" value="HEAT_MEC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012993">
        <property type="entry name" value="UME"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF125">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MEC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
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        <property type="entry name" value="TPR-like"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
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    </dbReference>
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        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0469">Meiosis</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="24">
        <location>
            <begin position="1484"/>
            <end position="2060"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="23">
        <location>
            <begin position="2172"/>
            <end position="2481"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="25">
        <location>
            <begin position="2476"/>
            <end position="2508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00030459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00033001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="2508" mass="282792" checksum="EC8DF16D69993277" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZS87</accession>
    <name>W6ZS87_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">V-type proton ATPase subunit E</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_92415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase E subunit family.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25985" checksum="0777FCBB4415BA96" modified="2014-04-16" version="1">MSQVHALSDDQVAGELKKMTAFIRQEAMEKANEIRLKADEEFAIEKSKLVRQEQASIDASYEKKFKQASMSQQITRSTVSNKSRLRILSARQELLNRLFEDAEKKLGDISKDKNKYQSILKNLILEGAYALNEDKLQVKVRKADIDLTKKAIEEAQTEFKKNLSKDVAITIDESDPLPEGSAGGAIIVGTNGKIDINNTFQERLKLLESQALPSIRVTLFGENENRKFHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSA5</accession>
    <name>W6ZSA5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_92434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSA5"/>
    <dbReference type="GeneID" id="19128077"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92434"/>
    <dbReference type="eggNOG" id="ENOG502QPIS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032141_0_0_1"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09615">
        <property type="entry name" value="Jacalin_EEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF1">
        <property type="entry name" value="SPHINGOMYELINASE DDB_G0288017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00915">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890006" description="Jacalin-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Jacalin-type lectin" evidence="2">
        <location>
            <begin position="299"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="440" mass="46591" checksum="A3787385A1C38A30" modified="2014-04-16" version="1">MHSILASAVALSSLLPLSLAQTSGTLNTLTFNVAGLPAALNGNDVPGDKTTNTARIGELFTKYNISLIHVQEDFNYHATLYASDKHPYRTATSGGVPFGSGLNSLSNFPFTSFNRVKWNTCSTFDSADCLTPKGFTAMRVKFAEGVVIDAYNLHADAGTTDADNKARADNLRQVSDYIKTYSIGNPVIVFGDSNSRYTRTNDIPAVFKEQNGMTDVWIDLIKKGVPPAKGADALLCSNPSTTNDCEIVDKTWYRGSAAVKLTARKFDYAGHMFLQDNGDILSDHNGVLVDFDWAAVDRFTLSDTFGGEGGNWFNDLDTVAGVSGAKVASVTLRGADRVDNIAFTLASGQTLAHGGTGGTAASLTLASGETLTSATMCQGQRNGTNRLFYVEFKTSAGKTLATGAKTSDCVTRTAPAGKSIVGLLGRAADGVDQAGLIYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSF0</accession>
    <name>W6ZSF0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">DASH complex subunit SPC34</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="22">Outer kinetochore protein SPC34</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">COCMIDRAFT_92255</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="27 28">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Chromosome</location>
            <location evidence="4">Centromere</location>
            <location evidence="4">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
            <location evidence="3">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DASH complex SPC34 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686845.1">
        <property type="nucleotide sequence ID" value="XM_007688655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSF0"/>
    <dbReference type="STRING" id="930090.W6ZSF0"/>
    <dbReference type="GeneID" id="19128039"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92255"/>
    <dbReference type="eggNOG" id="KOG0140">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_426981_0_0_1"/>
    <dbReference type="OrthoDB" id="10016597at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046359">
        <property type="term" value="P:butyrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00567">
        <property type="entry name" value="ACAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013966">
        <property type="entry name" value="Spc34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08657">
        <property type="entry name" value="DASH_Spc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="19" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="20" id="KW-0137">Centromere</keyword>
    <keyword evidence="7" id="KW-0158">Chromosome</keyword>
    <keyword evidence="14" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="16 23" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="17" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="13" id="KW-0274">FAD</keyword>
    <keyword evidence="10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="15" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0498">Mitosis</keyword>
    <keyword evidence="18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="26">
        <location>
            <begin position="219"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="25">
        <location>
            <begin position="470"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="33"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="23">
        <location>
            <begin position="155"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="24">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="24">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00044112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00044346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="EUC46626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="641" mass="69683" checksum="5BE1792DDC054787" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSZ3</accession>
    <name>W6ZSZ3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_25161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686620.1">
        <property type="nucleotide sequence ID" value="XM_007688430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSZ3"/>
    <dbReference type="GeneID" id="19120716"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25161"/>
    <dbReference type="HOGENOM" id="CLU_1427751_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="190" mass="20254" checksum="46B801CA6F828ACF" modified="2014-04-16" version="1">MQLFTTREVGIWVAGTAGSVGICATSVARPSGFKSPPQDVIPDISPPSSPSSPCLALPTPHKPKHSHPLSSSSSSSSSSTKNATSYSRANARSASLTTPFSSSSSSSSSSSSSSPPPSSLSSFLSPYNHATNASNVRTSTFSNFKMRSQWIFRRAARDNKWRRRGEHAASFSSWTGMRVGGWLIMQFTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTM1</accession>
    <name>W6ZTM1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial</fullName>
            <ecNumber evidence="11">1.14.15.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">2-methoxy-6-polyprenolphenol 4-hydroxylase</fullName>
            <ecNumber evidence="11">1.14.15.46</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">COQ6</name>
        <name evidence="13" type="ORF">COCMIDRAFT_31795</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-polyprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid. Also acts downstream of coq4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-polyprenyl)phenol to 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to coq6 from NADPH via a ferredoxin/ferredoxin reductase system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2-methoxy-6-(all-trans-polyprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:81183"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10858"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="ChEBI" id="CHEBI:84166"/>
            <dbReference type="EC" id="1.14.15.46"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:81195"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10930"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:64694"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="1.14.15.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.45" evidence="11"/>
    <dbReference type="EC" id="1.14.15.46" evidence="11"/>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682545.1">
        <property type="nucleotide sequence ID" value="XM_007684355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTM1"/>
    <dbReference type="STRING" id="930090.W6ZTM1"/>
    <dbReference type="GeneID" id="19121966"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31795"/>
    <dbReference type="eggNOG" id="KOG3855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_8_0_1"/>
    <dbReference type="OrthoDB" id="683240at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120538">
        <property type="term" value="F:2-methoxy-6-polyprenolphenol 4-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106364">
        <property type="term" value="F:4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000021">
        <property type="entry name" value="Ubiquinone biosynthesis monooxygenase COQ6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000245">
        <property type="entry name" value="Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03193">
        <property type="entry name" value="COQ6_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051205">
        <property type="entry name" value="UbiH/COQ6_monooxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000689">
        <property type="entry name" value="UbQ_mOase_COQ6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="3 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="40"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC50899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="494" mass="53179" checksum="AF372C3EDF545BF4" modified="2014-04-16" version="1">MPPQISLAPSRALLSPLTRCVRLQPRRRFLSSSADAPEVYDVVCVGGGPAGLSLLTGLKASPITNGLKVALIEGQDLHRSRLAQDASLETFSNRCSSLTPASVRNLQEIGAWAHVNQPRVQPYQEMQVWDGVSGARISFDWHTAKPLLTPRNPAQPTTIAYMIENVNTVTALLSRLEELGGVDFYTSTKVNSIDLGTDTDKMDFSSWPILTLSNGKSLAARLLVGADGANSPVRTFAGIESRGFDYNRHGVVASLKLEGQGWGGSDHKIAYQRFLPTGPIAMLPLPGNMSTLVWSTTPERAAKLKSLSQQEFVAMVNAGFRLSPTDLEYLHTLSSGHEEEVAWREKHTPVNEHAIPMRVANVQAGTVASFPLRMRHADTYTGERVALVGDAAHTIHPLAGQGLNQGQGDAAALVRTISYAVQTGQDIGSTLALESYNSERYAENNAMLGVCDKLHRLYSVESGPLVGLRSLGLRAVDAMGPLKGFFMSKAAGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUA9</accession>
    <name>W6ZUA9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_60881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682446.1">
        <property type="nucleotide sequence ID" value="XM_007684256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUA9"/>
    <dbReference type="GeneID" id="19124830"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_60881"/>
    <dbReference type="HOGENOM" id="CLU_153369_0_0_1"/>
    <dbReference type="OrthoDB" id="3790043at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="109" mass="12199" checksum="0F8972896E19E3EF" modified="2014-04-16" version="1" fragment="single">KYIPVYSPFLPTLLICSCMLFFFYHLVPSFTTATDDIVTLLVDNLNLRPSGSNDCTQEIGTVQCCSLFLDATPCLDECRKLHVDRETLSLTLAYDNCASQCLAEYHSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUV7</accession>
    <name>W6ZUV7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 128 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_89568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC47616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007687675.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_89568"/>
    <dbReference type="eggNOG" id="ENOG502RXK9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040908_4_0_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:fungal-type cell wall polysaccharide metabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ASL1"/>
    </dbReference>
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        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
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        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF10">
        <property type="entry name" value="ASL1-LIKE GLYCOSYL HYDROLASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="1">
        <location>
            <begin position="40"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="263" mass="28898" checksum="D65CFC4B5C7C5AC0" modified="2014-04-16" version="1">MALAGLSALTEASPLMPRAGGKRGIAFPKQHNGVAGSQWARMMAQSSKIFWMYDWEAVIDGEAPDLEYVPLLHSNQEWCASTWANNVANARKNYKVSHILSFNEPDQVGGGGSNIDVATAVDTHRKLIQPLAAEGLRIGSPAVTNGNEPGKGINWLKSFMDGCKDCQIDFVVTHYYAWAKPQDFKDYLNKFHDAFNLPLWITEFGVTEGNADEFLKDVLPWLDAQPWIERYAYHMAAPSDGNQFLITADGGSLSPAGQVYASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWQ8</accession>
    <name>W6ZWQ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SAGA-associated factor 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_87780</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the SGF11 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC48241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685260.1">
        <property type="nucleotide sequence ID" value="XM_007687070.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZWQ8"/>
    <dbReference type="GeneID" id="19127126"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87780"/>
    <dbReference type="eggNOG" id="KOG3322">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007205_0_0_1"/>
    <dbReference type="OrthoDB" id="442863at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070461">
        <property type="term" value="C:SAGA-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039182">
        <property type="entry name" value="Pop1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055079">
        <property type="entry name" value="POP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009723">
        <property type="entry name" value="Pop1_N"/>
    </dbReference>
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        <property type="entry name" value="POPLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013246">
        <property type="entry name" value="SAGA_su_Sgf11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731:SF3">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22770">
        <property type="entry name" value="POP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06978">
        <property type="entry name" value="POP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08170">
        <property type="entry name" value="POPLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08209">
        <property type="entry name" value="Sgf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pop1 N-terminal" evidence="13">
        <location>
            <begin position="52"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="POPLD" evidence="14">
        <location>
            <begin position="539"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="POP1 C-terminal" evidence="15">
        <location>
            <begin position="695"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="71"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="738"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1012"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1105"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="740"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1013"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1155"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1205"/>
            <end position="1235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU261113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC48241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1267" mass="140600" checksum="3D381B17744B03C1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYI6</accession>
    <name>W6ZYI6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_86440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrion-specific ribosomal protein mL54 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684749.1">
        <property type="nucleotide sequence ID" value="XM_007686559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYI6"/>
    <dbReference type="STRING" id="930090.W6ZYI6"/>
    <dbReference type="GeneID" id="19126854"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86440"/>
    <dbReference type="eggNOG" id="ENOG502S8RU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086132_1_0_1"/>
    <dbReference type="OrthoDB" id="10252718at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013870">
        <property type="entry name" value="Ribosomal_mL54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08561">
        <property type="entry name" value="Ribosomal_L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="33"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC48721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="237" mass="25604" checksum="14AE71BE3A791FF4" modified="2014-04-16" version="1">MICRSCLRAASRSAHQIPPVSLRRPQNPRFFTTASTLRNATPISSSTATQSMPRQGDSTSSHAPPTATSTSAAQPFSEPLTPAPGPDVKAAAAEAAKKKVAPLVKSSIPAGQPLKGLNFLKDRQDPIAAPDDEYPAWLWTLLDRQEKKAEKGAGDLFSKSKKQRRLAAKRLRKEQAENPEMLIPKVPLYEQTIDLPAGDGTLAGAVQAAEARDELTKAMRNKRRASIKEANFLKAMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYS7</accession>
    <name>W6ZYS7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_33728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684628.1">
        <property type="nucleotide sequence ID" value="XM_007686438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYS7"/>
    <dbReference type="GeneID" id="19122391"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33728"/>
    <dbReference type="HOGENOM" id="CLU_2589384_0_0_1"/>
    <dbReference type="OrthoDB" id="10482942at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="80" mass="8392" checksum="7CFAACF3B4CC1B2C" modified="2014-04-16" version="1">MPDLFPQICTRSRTRAHIPRHDGRQVVGYSSSPVALGACGLATLILATLAHLPTPSSLSSPHKALSHLLSPLPLVSSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZ40</accession>
    <name>W6ZZ40_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_2084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684368.1">
        <property type="nucleotide sequence ID" value="XM_007686178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZ40"/>
    <dbReference type="GeneID" id="19120001"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2084"/>
    <dbReference type="eggNOG" id="ENOG502SPMP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039960_1_0_1"/>
    <dbReference type="OrthoDB" id="21678at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="LIPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="43"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="401" mass="44395" checksum="912735487AA26E8B" modified="2014-04-16" version="1">MLSSSITKWISTILTLTSPSNNVNQASLLLTIKFPWIQSFASIGDSYSAGLGSGHRLDWLCSRYTHSYPNILHTSLLGTNPNRNHTFLACSGATSTEILATQVPALPPNLDLLTISAGGNDVGLTGILSACIYQFYMAAEDACAEAIDQARARIANETELYHNTSLLIDAAQQKMKPHHGIIYYTGYATFFGADDEACDNVTWAIWKDVEWKKQYLTRDLRGKLNDMVRSVNSILAQAVSDAGPGIHFIDYDAEIRQLRGRYCESGVVEPAPNRAGLAFYEWATVDQGENSTALLNQTGDGVPRFSFQGGIAREVEKTLERHPDWEIEHGKGFVDKEKDREKEGGDVGGEGWLGDEVHWLLPDSYKRVFHLRPMGHEVIARMVVDDLEKRSVGQGAEIEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZZ9</accession>
    <name>W6ZZZ9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684248.1">
        <property type="nucleotide sequence ID" value="XM_007686058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZZ9"/>
    <dbReference type="GeneID" id="19126609"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85126"/>
    <dbReference type="HOGENOM" id="CLU_2120679_0_0_1"/>
    <dbReference type="OrthoDB" id="3661627at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="126" mass="14469" checksum="64CE295A6583FE8B" modified="2014-04-16" version="1">MLKHINCFSNFKSFYIAVLFLSISTHLLVTRGGWQQCHMFAHTLLLHKFPRQVTIQRISQAPPRPSQQTHSTLIVQNSFLDSHISRTPCDIPTSLECIMNAARAAKRILLGHTRCKRAIKEKTTMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0L0</accession>
    <name>W7A0L0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phenazine biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_1617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683829.1">
        <property type="nucleotide sequence ID" value="XM_007685639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0L0"/>
    <dbReference type="STRING" id="930090.W7A0L0"/>
    <dbReference type="GeneID" id="19119906"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1617"/>
    <dbReference type="eggNOG" id="KOG3033">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048756_1_0_1"/>
    <dbReference type="OrthoDB" id="412383at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774:SF32">
        <property type="entry name" value="ANTISENSE-ENHANCING SEQUENCE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="34982" checksum="8D007015C1BF8123" modified="2014-04-16" version="1">MATSAELDFVTVDVFTSKPYQGNPLAIVRIPSGRTLTQEHKQVIAREFNLSETTFLHENAEGEANLAWTVDIFIPSRELPFAGHPTVGTACYVLGRTAQAQGLDHGVIEAAFRLKAGPVRLQYDVAKKTTKASIPHDVHIHQQRYTNEMLFKLQPRLGEAHRQDKIKVKDDFPIVSIVKGMTFVLIELESVEALAMVSLAGQSLVVNGLDEGWDETFVGTYFFVRVANKNQGVTTLRTRMIEGPFEDPATGSAASDLAAYLSLTEGGANKTFQYEIVQGAEMGRRSEILIDVDMNENGSISEVRLEGGAVQVMKGQVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0U0</accession>
    <name>W7A0U0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="2">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_32888</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="2"/>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683754.1">
        <property type="nucleotide sequence ID" value="XM_007685564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0U0"/>
    <dbReference type="STRING" id="930090.W7A0U0"/>
    <dbReference type="GeneID" id="19122200"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32888"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_4_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="230" mass="24642" checksum="6278B32B23FA20D3" modified="2014-04-16" version="1">MKIRKIAFTGSTLTGHAILKALAESSLKKVSLSLGGKSPTIIFGDANLEETATWAAIGITAGEGDICTAGSQIHVQDTVYGRSLEAFSNRYKSLAPSDTMALGTNKGSFISDQKQIGNSNAIETAAFFDVPEDSAIMKEEIFGPVASIAKFREEEEEEKEEEEEEESIQKANNTEYGSSAAISIQGLVRAHRFVDRLDSGQVTINAWSLLIANLPFGGTKQSGFGRDDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W7A246</accession>
    <name>W7A246_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_1277</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683375.1">
        <property type="nucleotide sequence ID" value="XM_007685185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A246"/>
    <dbReference type="GeneID" id="19119830"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1277"/>
    <dbReference type="HOGENOM" id="CLU_1001113_0_0_1"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11395">
        <property type="entry name" value="bHLHzip_SREBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="203"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="296" mass="31758" checksum="6916E89EDE2EC2D2" modified="2014-04-16" version="1">MAVHNLPAFTAGPDPTYSPPESDTFPSPDELESPCYGDSYPPLSEYSSLDSNSGPCFTRPSEPVDPSNSLNWNAPLSNGFMSPPSAVVCPPATHGLPTSPQFAPMWQTGVPTPLSTSGDFQHGYISPEYTASAFPSVPSPLPTPSNHGSPASLSPVVATNPTPSPQDPISKPLPRKRGRPRIHRPASEPSATGSTSPAKHARTQCMPHTEVERKYREKLNAELERLRKAVPLLPQSDASSESGGVKPSKSMVLAVAIDYIKELERQRDLAVEEVERLGGKVKFGRVGGWRRGSEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W7A349</accession>
    <name>W7A349_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">acetylglutamate kinase</fullName>
            <ecNumber evidence="6">2.7.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">COCMIDRAFT_82130</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>N-acetyl-L-glutamate + ATP = N-acetyl-L-glutamyl 5-phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 19">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 19">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 19">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 19">In the C-terminal section; belongs to the NAGSA dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">In the N-terminal section; belongs to the acetylglutamate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="6"/>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683082.1">
        <property type="nucleotide sequence ID" value="XM_007684892.1"/>
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    <dbReference type="STRING" id="930090.W7A349"/>
    <dbReference type="GeneID" id="19125996"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82130"/>
    <dbReference type="eggNOG" id="KOG2436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4354">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006384_4_0_1"/>
    <dbReference type="OrthoDB" id="438291at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:L-arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23936">
        <property type="entry name" value="AGPR_C_ARG5_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd24149">
        <property type="entry name" value="AGPR_N_ARG5_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04263">
        <property type="entry name" value="DUF619-NAGK-FABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000019">
        <property type="entry name" value="Bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000046">
        <property type="entry name" value="N-acetylglutamate kinase / N-acetylglutamate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058924">
        <property type="entry name" value="AGPR_dimerisation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011241">
        <property type="entry name" value="NAGK/NAGSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006855">
        <property type="entry name" value="Vertebrate-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342:SF0">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04768">
        <property type="entry name" value="NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22698">
        <property type="entry name" value="Semialdhyde_dhC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036440">
        <property type="entry name" value="ARG5-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51731">
        <property type="entry name" value="GNAT_NAGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 19" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="12 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="16 19" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17 19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13 19" id="KW-0521">NADP</keyword>
    <keyword evidence="10 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="22">
        <location>
            <begin position="337"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="522"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="540"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="active site" evidence="20">
        <location>
            <position position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR036440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EUC50456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="885" mass="98151" checksum="111AD0EE856884B9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3G5</accession>
    <name>W7A3G5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Agmatinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_81424</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684699.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W7A3G5"/>
    <dbReference type="GeneID" id="19125867"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81424"/>
    <dbReference type="eggNOG" id="KOG2964">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_1_0_1"/>
    <dbReference type="OrthoDB" id="288726at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033389">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via agmatine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11592">
        <property type="entry name" value="Agmatinase_PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000001">
        <property type="entry name" value="Agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF28">
        <property type="entry name" value="HYPOTHETICAL ARGINASE FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0745">Spermidine biosynthesis</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887891" description="Agmatinase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR036979-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="373" mass="39795" checksum="9464112EF744CE4C" modified="2014-04-16" version="1">MALVSLLSITPFLTVAYTREITFPPVSGYGSQQAFPQGLFETDVTQAKFAGLTTYASLPYVHCLAPEGDDVEPFDIAILGAPFDTAVTGRPGTRFGPGGIRAGSRRMGPSWSIYTGENVFFDWAKIVDCGDAPLTFLDNTVALKQLDKAHEIISSRDANSSEHGRTPKIITLGGDHTTTLPALRSAHNHWGPVSVIHFDSHIDTWDPKVLGGGISHYAGVNHGTFLHIAHEEGLIRNTSIHAGIRAPVLRPKGDVRNDIRCGFDMVKARDLDRIGVSGIIETLKARVGDSKVYISVDIDVLDPAFAPATGTAEVGGWSTRELLSILDGLAGLDVIGADIVEVAPIYDNPGEPTVLAAAEIVLSLITLMVKAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3Z8</accession>
    <name>W7A3Z8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycoside hydrolase family 71 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_81223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682740.1">
        <property type="nucleotide sequence ID" value="XM_007684550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3Z8"/>
    <dbReference type="STRING" id="930090.W7A3Z8"/>
    <dbReference type="GeneID" id="19125825"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81223"/>
    <dbReference type="eggNOG" id="ENOG502SK1G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019141_3_0_1"/>
    <dbReference type="OrthoDB" id="3257981at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051118">
        <property type="term" value="F:glucan endo-1,3-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11577">
        <property type="entry name" value="GH71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005197">
        <property type="entry name" value="Glyco_hydro_71"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03659">
        <property type="entry name" value="Glyco_hydro_71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="371" mass="41456" checksum="6D22E4C53481BD2B" modified="2014-04-16" version="1">MFNHADELGDFSLFFSFDHGKGILKDPLDYATYFTKYSGRPSYLKMKDRNSDARKPVLSTFGGENISNDRWNQFKRKVGDVLIIPGFSEVYNPTTSFFQGRSALDGVFNWNSWPTVQEGRVTVSAAVDRTFQTAARNANKYFMMGISPLQFKHTSYGNWYRRGEDNLENRIGQILNVQPDMVQLQTWNDGGESHYMGRLHPEPLDDRTKALTDGYDHTGYWQILPSFINAWKRGDTSTANMYPTNGKPVQGTFWHHTLTIGGSCYADEIAKPDSIVRGGEDAVSGVLLVAQNKQGLKAEVKVGNVRLGNIISLTPGFNKFKLTGLEKLVPGKVQVEVWDGSSMVGGGYGSIEVTKEKPLCNYNFQVVGLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YM61</accession>
    <name>W6YM61_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Reticulon-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_9775</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Endoplasmic reticulum membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964175">
        <property type="protein sequence ID" value="EUC40322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693154.1">
        <property type="nucleotide sequence ID" value="XM_007694964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YM61"/>
    <dbReference type="STRING" id="930090.W6YM61"/>
    <dbReference type="GeneID" id="19129117"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9775"/>
    <dbReference type="eggNOG" id="KOG1792">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046578_1_0_1"/>
    <dbReference type="OrthoDB" id="567788at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003388">
        <property type="entry name" value="Reticulon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02453">
        <property type="entry name" value="Reticulon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50845">
        <property type="entry name" value="RETICULON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Reticulon" evidence="8">
        <location>
            <begin position="128"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="327"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="372" mass="40720" checksum="26FB5452D28B8F29" modified="2014-04-16" version="1">MSGEAPRVELNSTDLDFDLTAPVNQKLSQMNSDAAPLPNGNADHSLPNGAVQTNGSLLDSASNAINAANNHPSVQNIKNTVMNGPVAQNVKAEGAKTRDEFADLANSKTIPDQKAATGQNLTHYHSMFYRLLSWKNPRATAIAFASTVVFIFAARYLNLIRYIFKSSYLVLGATATAEIAGQLTIGRGITSQFRPRQYFTIPKASLERLTDDFEQLINFFVIESQRIVFAENVYVTVAAFFASLISYFLIKWVPLWGLGLIATHIAFLGPLIYIKNKDVIDAQLEKGYTIANQQAQQVKGLANQHAENAMKTVQGYTQQATAKAQETVNQYRGRSASPEVKKQTLPNAPKHEPIAESSSEEEDDVPVAQAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMD2</accession>
    <name>W6YMD2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_108848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964166">
        <property type="protein sequence ID" value="EUC40432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693050.1">
        <property type="nucleotide sequence ID" value="XM_007694860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMD2"/>
    <dbReference type="GeneID" id="19119320"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108848"/>
    <dbReference type="HOGENOM" id="CLU_1541056_0_0_1"/>
    <dbReference type="OrthoDB" id="3784677at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="155" mass="16874" checksum="E77A5FC2D8F225EE" modified="2014-04-16" version="1">MSSNTTKPFTPTTELHDLGATRFDRDTAAPSDRDTALLHRHPAVPVITPQGRAPPGLEAKVHEWTTFRFTTEDVDRVEELKGDLHGGMLHRVNRAARGEVGGGPVMRRGGKGRNEDMAQETTLCGGRKGEGDVAPVAKGMAEEMGKDMFWSEPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMU0</accession>
    <name>W6YMU0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Luciferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_108395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964152">
        <property type="protein sequence ID" value="EUC40602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692880.1">
        <property type="nucleotide sequence ID" value="XM_007694690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMU0"/>
    <dbReference type="GeneID" id="19119236"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108395"/>
    <dbReference type="eggNOG" id="ENOG502QSR6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022256_0_0_1"/>
    <dbReference type="OrthoDB" id="5561043at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051260">
        <property type="entry name" value="Diverse_substr_monoxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011:SF30">
        <property type="entry name" value="XENOBIOTIC COMPOUND MONOOXYGENASE, DSZA FAMILY (AFU_ORTHOLOGUE AFUA_6G01920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="2">
        <location>
            <begin position="43"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="483" mass="53779" checksum="CB5A39395F1149F6" modified="2014-04-16" version="1">MASASNKIDTEPSKKRIFLNGFDMFTPSHLSFGQWRRPEDRSKDKRRDLSYWIDVAQILERGDITAFFLADTYGQHDVYKGSAEPTVRTACQYPMGDPSIPVTAMAAATKNLSFAITTSTSYESPFVVAKRFSTIDHLTKGRFGWNIVTSFKESAAKAVGVPFVEHDKRYAIADDYLRCLYKIWEASWADDALKEDAENEKYADFDRIRYIQHQTEIFKINASHILDPSPQRTPFLFQAGTSSAGMAFAASHAEGVFVAAPSPHILAPRVANIRREAEALGRDPRSVKVFAVITPIIGHTQEEAQEKYQRALEFASAEGGLAFYSSNAGIDLSKYDLDCEITPDDVSVDGRVHSLVNSLKYHGNDTPSWTPRNIGKAVSLGGNGPVPVGNAEKVADILEEWIEIADLDGFNVGYVVSPGSFEDLVDLLVPELRRRGRYPEKKDLDSGVTLREQIYGRGQSKLRNDHIGSSYKYEHYEKIVGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNL8</accession>
    <name>W6YNL8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_107466</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964129">
        <property type="protein sequence ID" value="EUC40952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692539.1">
        <property type="nucleotide sequence ID" value="XM_007694349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNL8"/>
    <dbReference type="GeneID" id="19119055"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107466"/>
    <dbReference type="eggNOG" id="ENOG502SMC4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021916_2_1_1"/>
    <dbReference type="OrthoDB" id="5386330at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF48">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="598" mass="67235" checksum="02726F8740BA1A4B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNM9</accession>
    <name>W6YNM9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">ER membrane protein complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_107434</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964128">
        <property type="protein sequence ID" value="EUC40967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692522.1">
        <property type="nucleotide sequence ID" value="XM_007694332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNM9"/>
    <dbReference type="STRING" id="930090.W6YNM9"/>
    <dbReference type="GeneID" id="19119046"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107434"/>
    <dbReference type="eggNOG" id="KOG3318">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098404_2_0_1"/>
    <dbReference type="OrthoDB" id="369569at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009445">
        <property type="entry name" value="TMEM85/Emc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19315">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06417">
        <property type="entry name" value="EMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017207">
        <property type="entry name" value="UCP017207_TM-p85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="184" mass="20359" checksum="F4D58F85045E3846" modified="2014-04-16" version="1">MAAAPPPPPQWVVDLNSTPASKPKNPALIDPPGYTASLTKKERSQASKNQRVPPTADEMDTLKMKKAWEVAIAPAKQLPMNAFGMYMTGNTLQIFSVFMVFTLFKTPVLAVLGLQRTFAPYQTPGTAGRLLGVKLVYIACNLLMLALGIWKVNAMGLLPTTRSDWLAWESERTWSERAVPQEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNU8</accession>
    <name>W6YNU8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_107159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HyuE racemase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964122">
        <property type="protein sequence ID" value="EUC41062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692423.1">
        <property type="nucleotide sequence ID" value="XM_007694233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNU8"/>
    <dbReference type="STRING" id="930090.W6YNU8"/>
    <dbReference type="GeneID" id="19118992"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107159"/>
    <dbReference type="eggNOG" id="KOG0806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_446181_0_0_1"/>
    <dbReference type="OrthoDB" id="412018at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047661">
        <property type="term" value="F:amino-acid racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052186">
        <property type="entry name" value="Hydantoin_racemase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053714">
        <property type="entry name" value="Iso_Racemase_Enz_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047:SF6">
        <property type="entry name" value="CN HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="606" mass="66044" checksum="03D37679687DBA8E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQA5</accession>
    <name>W6YQA5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pre-rRNA-processing protein IPI3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_105684</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the WD repeat IPI3/WDR18 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964094">
        <property type="protein sequence ID" value="EUC41617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691868.1">
        <property type="nucleotide sequence ID" value="XM_007693678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQA5"/>
    <dbReference type="STRING" id="930090.W6YQA5"/>
    <dbReference type="GeneID" id="19118729"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105684"/>
    <dbReference type="eggNOG" id="KOG0646">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025946_1_0_1"/>
    <dbReference type="OrthoDB" id="756370at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120330">
        <property type="term" value="C:rixosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000929">
        <property type="entry name" value="Ribosomal assembly complex component Ipi3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045227">
        <property type="entry name" value="WDR18/Ipi3/RID3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763">
        <property type="entry name" value="WD-REPEAT PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 5 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="123"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="174"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="504"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="552" mass="59097" checksum="31B568FA5B4F1527" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQH8</accession>
    <name>W6YQH8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964223">
        <property type="protein sequence ID" value="EUC39915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693564.1">
        <property type="nucleotide sequence ID" value="XM_007695374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQH8"/>
    <dbReference type="GeneID" id="19119553"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110165"/>
    <dbReference type="HOGENOM" id="CLU_1120080_0_0_1"/>
    <dbReference type="OrthoDB" id="3680878at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="251" mass="27879" checksum="2E1381D6ED3949CC" modified="2014-04-16" version="1">MSRSRSNEPTPCHRTQHDSAAMQICEGGRRGGVAARGEGSDSTMPSKRDSNIPAHQCFLLSEDEDSDWDPYPPSPPLSPKTVVIEPRSRYSQRTSTLHQYGSAKRRPGWKPSLKEELLRRTSMDAAMGHTEPRASTQTGRSRSKTTRLDYTAEEGIEIPQPRRRRGSTLLHPSSPIIGSAILHTDAPPTQTDTPSLPPQPYPCFENRPKTLLRKGSSLLHPSPPLSDAESEASMRIAQLKTVLSFPPRKQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQP1</accession>
    <name>W6YQP1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_105438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964089">
        <property type="protein sequence ID" value="EUC41732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691769.1">
        <property type="nucleotide sequence ID" value="XM_007693579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQP1"/>
    <dbReference type="GeneID" id="19118682"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105438"/>
    <dbReference type="HOGENOM" id="CLU_581365_0_0_1"/>
    <dbReference type="OrthoDB" id="3797115at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="470" mass="53616" checksum="C888F266B77113DF" modified="2014-04-16" version="1">MNRHITPSPSSTAVSLTDSRDGSTRRRNTLDTSAQAAEIDYLKRQLQSLARAKAKASKKSDDLFREISSWSEKFEKEKARRTQSEEKLSKERRVVIGLKKEMNELKDKTNKEVREAKSRLENERKKWMGQGIFTNTKPKGVVQTSASNLQGRIKYLEEENARLESLTKSHDYDELYGEAQQQIDDAMALLRTTEAELEELRYLETADEELTEQHYLDTLKIEELSDELRCCKATVEKLEDEIAAADEQRSVESPTSSNSNIPDISPGAFSTPTAPLVDTAETDYLRQSLGDLEIENQKIICAFAKLSHEHCDTMVELDKLSEQIFTLHEANLDLEARNDALESQLDTAVQILRATIEETGQDPPAHNRTYTTLSDSDFVEDLPTPEPNSRTPVTIRLFEKRDWPLLYHVQRTLFRTSPLQIDGPSVLVREFVKLMQGEDAEFQEMKGRVEKLERAFEVGVQEMKALKQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRJ3</accession>
    <name>W6YRJ3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Arsenical-resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_41507</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964196">
        <property type="protein sequence ID" value="EUC40118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693363.1">
        <property type="nucleotide sequence ID" value="XM_007695173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRJ3"/>
    <dbReference type="GeneID" id="19124071"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41507"/>
    <dbReference type="eggNOG" id="ENOG502QPKH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022869_0_0_1"/>
    <dbReference type="OrthoDB" id="187348at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015104">
        <property type="term" value="F:antimonite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000009">
        <property type="entry name" value="Arsenite transporter, ACR3 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057:SF1">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="ARSENITE EFFLUX TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0059">Arsenical resistance</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="202"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39519" checksum="45A2A26BE96CC8E1" modified="2014-04-16" version="1">MALSSEEPQPVDTEPISPHRDADVEKLQLKEQVAVKDRSVIKGLGWLDRFLALWILVAMIIGILLGNFVEETGPALQKGKFVGVSIPIALGLLVMMYPILCKVRYETLYCLFRTRALWVQIGLSIFMNWIIAPLLMLGLAWAFLPDRSDLRTGLISVGLARCIAMYCAILVAVNSILQMILYAPLAILFIKVISRENGTVAVSYGTVATSVAVFLGIPLGAAVLTRFTLRTFVSPEWYEKTFLKWLAPWSLIGLLYTILVLFASQGRQVVHQVASVVRVAAPLIVYFVLGYGYKLGATQSLTAASNNFELAIAVAVATYGPNSDQALAATVGPLIEVPVLIALVYLVRCMGSRWAWKQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT39</accession>
    <name>W6YT39_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_9405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964141">
        <property type="protein sequence ID" value="EUC40755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692712.1">
        <property type="nucleotide sequence ID" value="XM_007694522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT39"/>
    <dbReference type="SMR" id="W6YT39"/>
    <dbReference type="STRING" id="930090.W6YT39"/>
    <dbReference type="GeneID" id="19128380"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9405"/>
    <dbReference type="eggNOG" id="KOG2684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_3_1_1"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="5">
        <location>
            <begin position="2"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="274" mass="30192" checksum="1F448BCE76CB93B4" modified="2014-04-16" version="1">MNTSDNHNYSAFADLLAESSRVLCLVGAGLSAPSGLATWRGTNGLWNDINVKELASPKKFREDPITVWRFYGERLLEALEARPNAAHHALAALADWHQGWLTINQNVDGLLEQTGHPMSRLLNVHGTLKTVRCTACNYSIDVHKPEDVPFLLSLSNTDHKARPVALSDLPHCPQCANLLRPRVVWFGERLAAGAPDNVDEWMSEEYIDLVITAGTSLQVFPAAEWVSTARADGASLAIIDTEDYETVDGFDEGDWLFKGDIAFTLPKIVDILNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT61</accession>
    <name>W6YT61_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heme-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_102964</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964054">
        <property type="protein sequence ID" value="EUC42652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690854.1">
        <property type="nucleotide sequence ID" value="XM_007692664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT61"/>
    <dbReference type="GeneID" id="19118197"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102964"/>
    <dbReference type="eggNOG" id="ENOG502SUKI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103773_2_1_1"/>
    <dbReference type="OrthoDB" id="5075159at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="entry name" value="Haem-degrading domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052517">
        <property type="entry name" value="GlcG_carb_metab_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34309:SF1">
        <property type="entry name" value="PROTEIN GLCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34309">
        <property type="entry name" value="SLR1406 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="HbpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="GlcG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="15294" checksum="528A78D087AEDA8B" modified="2014-04-16" version="1">MNNTNGIGSTPAQRFVISADQAQTVIKAAVANATALQIPENIAIVDPAGMLVAFHRMDNAYLGSIDISQKKARTAVLFNGLSSGDLYAAVQPGAPLYSAENSNGGLIVFGGGLPIYLNGRLIGGVGVSGGSVEQDLSAAYAGVEGLGASSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTZ1</accession>
    <name>W6YTZ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UNC-45/Cro1/She4 central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_102280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964045">
        <property type="protein sequence ID" value="EUC42922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690578.1">
        <property type="nucleotide sequence ID" value="XM_007692388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTZ1"/>
    <dbReference type="STRING" id="930090.W6YTZ1"/>
    <dbReference type="GeneID" id="19118050"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102280"/>
    <dbReference type="eggNOG" id="KOG4151">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016305_0_0_1"/>
    <dbReference type="OrthoDB" id="5574718at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024660">
        <property type="entry name" value="UCS_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994:SF1">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11701">
        <property type="entry name" value="UNC45-central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="UNC-45/Cro1/She4 central" evidence="4">
        <location>
            <begin position="219"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="818" mass="89917" checksum="84A6FC16B5AE7973" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUS8</accession>
    <name>W6YUS8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lysine decarboxylase-like protein-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_101500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964037">
        <property type="protein sequence ID" value="EUC43182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690310.1">
        <property type="nucleotide sequence ID" value="XM_007692120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUS8"/>
    <dbReference type="GeneID" id="19117879"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101500"/>
    <dbReference type="eggNOG" id="ENOG502QSR9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058336_1_0_1"/>
    <dbReference type="OrthoDB" id="414463at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000018">
        <property type="entry name" value="Lysine decarboxylase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00730">
        <property type="entry name" value="Rossman fold protein, TIGR00730 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="23740" checksum="6408D2D9E113A874" modified="2014-04-16" version="1">MATTNDTPKQPVVCVFCGASSGTSPVHMEAARALAHALHKANTKLVYGGGTVGLMGEVARTLVSLSGPDSVHGIIPAALTRLEQNHDPADPDKHSIDESIYGRTTVVKDMHTRKQMMAQEVIKGGPGGGFVALSGGYGTFEELMEITTWNQLGIHSMPVIVFNVDGYWSGLIEWVKNAVKSGFIAPTNAGILSEALTADEVITCLNEYENAPGRFNLTWEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY31</accession>
    <name>W6YY31_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phenylalanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_39440</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="KI964059">
        <property type="protein sequence ID" value="EUC42490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690975.1">
        <property type="nucleotide sequence ID" value="XM_007692785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY31"/>
    <dbReference type="STRING" id="930090.W6YY31"/>
    <dbReference type="GeneID" id="19123690"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39440"/>
    <dbReference type="eggNOG" id="KOG2783">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022696_0_1_1"/>
    <dbReference type="OrthoDB" id="4457at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070156">
        <property type="term" value="P:mitochondrial phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.380:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000053">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="entry name" value="Ferrodoxin-fold anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00469">
        <property type="entry name" value="pheS_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="Anticodon-binding domain of PheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="15">
        <location>
            <begin position="79"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="16">
        <location>
            <begin position="365"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00057761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00073229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC42490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="476" mass="54123" checksum="12F21E499DA40C4E" modified="2014-04-16" version="1">MLGRDVSPATFKGTIADMETSVGVSTYAAQYSPGELPKEVKIEGKTYKTDEWMNTPSSILDAIPRRLHLQPDHPLTITRKLIESRFPGYKTHNNLFPIVTTGQNFDSLGFPLDHIGRSRTDTYYLNKETVLRTHTSAHQADTFRNNESEGYLISADVYRRDAIDRSHYPVFHQMEGARTWDRQQAEKEGKNLAYIIWEDVEKIPKHDIAVEDPNPTYHAERNPLQTGHSPEAVEAIAAHLKRSLEDMVVTIFNAAKSASDAETSGEPLKVRWVEAYFPFTSPSWELEVFWQGDWLEVLGCGIVSQPILNNASVPNRIGWAFGLGLERIAMLLYSIPDIRLFWSKDERFLLQFSEQKSISPFVPFSKYPECFKDVSFWLRGGSSAAGTPIASAAPVPTSTPSFHENDVMEIAREICGDLVEDVRLVDEFVHPKTGRRSMCYRINYRSLERTLTNKETNELHERLRTTIVARLGVELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYQ5</accession>
    <name>W6YYQ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exocyst complex component SEC15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_7775</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the SEC15 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964052">
        <property type="protein sequence ID" value="EUC42708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690772.1">
        <property type="nucleotide sequence ID" value="XM_007692582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYQ5"/>
    <dbReference type="STRING" id="930090.W6YYQ5"/>
    <dbReference type="GeneID" id="19125386"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7775"/>
    <dbReference type="eggNOG" id="KOG2176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009437_2_0_1"/>
    <dbReference type="OrthoDB" id="10267033at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.30:FF:000004">
        <property type="entry name" value="Exocyst complex component SEC15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.30">
        <property type="entry name" value="Exocyst complex subunit Sec15 C-terminal domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007225">
        <property type="entry name" value="EXOC6/Sec15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046361">
        <property type="entry name" value="EXOC6/Sec15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042045">
        <property type="entry name" value="EXOC6/Sec15_C_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048359">
        <property type="entry name" value="EXOC6_Sec15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702">
        <property type="entry name" value="SEC15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20651">
        <property type="entry name" value="EXOC6_Sec15_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04091">
        <property type="entry name" value="Sec15_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025007">
        <property type="entry name" value="Sec15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC6/Sec15 N-terminal" evidence="7">
        <location>
            <begin position="49"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex subunit EXOC6/Sec15 C-terminal" evidence="6">
        <location>
            <begin position="400"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR025007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="771" mass="87848" checksum="8794C4ED4AA9B4B7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYZ6</accession>
    <name>W6YYZ6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_102617</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964049">
        <property type="protein sequence ID" value="EUC42795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690708.1">
        <property type="nucleotide sequence ID" value="XM_007692518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYZ6"/>
    <dbReference type="STRING" id="930090.W6YYZ6"/>
    <dbReference type="GeneID" id="19118117"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102617"/>
    <dbReference type="eggNOG" id="KOG0387">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_4_0_1"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000019">
        <property type="entry name" value="DNA excision repair protein ERCC-6-like 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029256">
        <property type="entry name" value="Heliccase-ass-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057931">
        <property type="entry name" value="RHH_ERCC6L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25806">
        <property type="entry name" value="RHH_ERCC6L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14773">
        <property type="entry name" value="VIGSSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="272"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="647"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="55"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="961"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
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            <end position="73"/>
        </location>
    </feature>
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        <location>
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            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="961"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1067" mass="120811" checksum="09A6D3F3065105B5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZH0</accession>
    <name>W6YZH0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_9283</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964130">
        <property type="protein sequence ID" value="EUC40934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694359.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19128155"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9283"/>
    <dbReference type="eggNOG" id="ENOG502QVU5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_1_1_1"/>
    <dbReference type="OrthoDB" id="10250730at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07730">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF5">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="64"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="369" mass="40840" checksum="591D3E51234BB3A2" modified="2014-04-16" version="1">MAEKSPEITWHPIPHSDATCKVHLIQAGGIYIPYDLVLLPDSDKPSDPSRSEASIEERKTYYAPDYVFLIEHMASGTKYMFDLGIRPDLENLPPFIKENVLPVFKCEPKSPEHILREHGSPEQQPEKVKAVIFSHMHFDHMGDGAKGGFEGAELWVGPTCCTYARPGYPVEERAPTLSDSLPVDGSRKVVECYIPDDLLRDTGDKRAGQVMEGLKEGKYAAVDLKKPEWICIGAFERAYDVFGDGAAYIVDAPGHSPGHQMMLVRTTSSSGSEESSFVLLGGDCFHHANVLQDPNRAARPPYSKGCMHVDPEKAVNMMLRTREFARKDNVWVIGAHDATIGQGIHPGVKELTGLTDITNWQASGWKTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZP5</accession>
    <name>W6YZP5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_38964</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="Lowry S."/>
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                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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</entry>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_27944"/>
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    <dbReference type="OrthoDB" id="3690070at2759"/>
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            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="123" mass="13649" checksum="87F175CE8CE8C9A4" modified="2014-04-16" version="1">MEQATQEDISLKFCGQEPHLPATTSDSKQYTQTDCPVHGRPILEPPRQNIPPGVHPSQRLEYTPLWHLPVGMSGGCRVGTSASAGCICVHNPDILKDEMTREMEVIVQEAKQKGKKQEEKKST</sequence>
</entry>
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            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
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        <name evidence="7" type="ORF">COCMIDRAFT_66973</name>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:DNA-templated transcription"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Zn2Cys6_DnaBD"/>
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    </dbReference>
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        <location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41474.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="598" mass="67427" checksum="95452C109FAEB2BC" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1M7</accession>
    <name>W6Z1M7_COCMI</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
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    </reference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="107"/>
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            <end position="161"/>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC43618.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="174"/>
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    </feature>
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    </evidence>
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            <dbReference type="EMBL" id="EUC43875.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
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    </evidence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
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    </dbReference>
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    </dbReference>
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        <location>
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        <location>
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    </feature>
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        <location>
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            <end position="422"/>
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    </feature>
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        <location>
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            <end position="639"/>
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    </feature>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z383</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="30421" checksum="F035074C80D1FC7E" modified="2014-04-16" version="1">MLLLGLTGSIATGKSTVSSLLSKPPYSLPIIDADLIARQVVEPGTAGYNAIVKYFSPSTPDLLLPDATPKGAPLNRPALGRRVFGSGEEKERDRKMLNSIVHPAIRREMYKQMIWAYLRGNWAVVLDVPLLFESGWERYCGTILVVGVSDPAIQIQRLRARDSHLTEEDARNRVMSQGDVREKAERCLRRGPGNGVVVWNDHDREHLEKEVQRVMQDIRKRSPRWWSFLLWVFPPFGAMAGLWSWYKMRNVQLQWESEKKKEKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3G1</accession>
    <name>W6Z3G1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450 76C3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_98757</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689252.1">
        <property type="nucleotide sequence ID" value="XM_007691062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3G1"/>
    <dbReference type="GeneID" id="19129326"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98757"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF11">
        <property type="entry name" value="OXIDOREDUCTASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886417" description="Cytochrome P450 76C3" evidence="6">
        <location>
            <begin position="21"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="61009" checksum="E730D777EAD92DB7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3H2</accession>
    <name>W6Z3H2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="12">DHBP synthase</shortName>
            <ecNumber evidence="3 12">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_6209</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="12">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="12">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="3 12"/>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688974.1">
        <property type="nucleotide sequence ID" value="XM_007690784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3H2"/>
    <dbReference type="STRING" id="930090.W6Z3H2"/>
    <dbReference type="GeneID" id="19124880"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6209"/>
    <dbReference type="eggNOG" id="KOG1284">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020273_3_1_1"/>
    <dbReference type="OrthoDB" id="60371at2759"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.870.10:FF:000002">
        <property type="entry name" value="3,4-dihydroxy-2-butanone 4-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327:SF18">
        <property type="entry name" value="3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327">
        <property type="entry name" value="GTP CYCLOHYDROLASE II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0318">Glutathionylation</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 12" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0686">Riboflavin biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC44510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="253" mass="27089" checksum="D4489A69F41E2C31" modified="2014-04-16" version="1">MTAELENGLPANGTNGVNGKVTETINSTPSHPAFDSIPDVIQAFANDEFVIVLDSPSRENEGDLIIAASALTPSKASFMIRYSSGYICAPLPVSRAAALHLPQMVSDNADPNRTAYAVSIDAADPSVTTGISAHDRSLTCRMLADPSAKASHFRRPGHILPLQARDGGVRERMGHTEAAVDLCRLAGKEPVGVICELITDGEEVPGKPEFKDGGMMRRDECLEFGKKWGIKVCTIEDLVRYIEENEGVLGKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4L1</accession>
    <name>W6Z4L1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Glycosyltransferase family 57 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_37339</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688583.1">
        <property type="nucleotide sequence ID" value="XM_007690393.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z4L1"/>
    <dbReference type="GeneID" id="19123229"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37339"/>
    <dbReference type="eggNOG" id="KOG1245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2576">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002631_0_0_1"/>
    <dbReference type="OrthoDB" id="1689333at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018501">
        <property type="entry name" value="DDT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013136">
        <property type="entry name" value="WSTF_Acf1_Cbp146"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32075">
        <property type="entry name" value="ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32075:SF6">
        <property type="entry name" value="ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02791">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10537">
        <property type="entry name" value="WAC_Acf1_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50827">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51136">
        <property type="entry name" value="WAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="217"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="WAC" evidence="17">
        <location>
            <begin position="517"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="DDT" evidence="16">
        <location>
            <begin position="961"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="889"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1026"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1228"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1485"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1539"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1182"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="892"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1032"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1275"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1287"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1511"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1546"/>
            <end position="1562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC44905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1562" mass="177697" checksum="1E9F10B028DB101A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4N4</accession>
    <name>W6Z4N4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_96903</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688550.1">
        <property type="nucleotide sequence ID" value="XM_007690360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4N4"/>
    <dbReference type="STRING" id="930090.W6Z4N4"/>
    <dbReference type="GeneID" id="19128940"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96903"/>
    <dbReference type="eggNOG" id="KOG0811">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059257_2_0_1"/>
    <dbReference type="OrthoDB" id="364348at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15840">
        <property type="entry name" value="SNARE_Qa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000059">
        <property type="entry name" value="Related to syntaxin 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF38">
        <property type="entry name" value="LD27581P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14523">
        <property type="entry name" value="Syntaxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
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            <begin position="1"/>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="272" mass="30914" checksum="2E06BF9420B80475" modified="2014-04-16" version="1">MSFQRSSALESQPTTWRREDDAAYADDPEFRDFADKLSDDLFALTRNVARLSQETAKLGTKHETARVRERVKTTVEETSDKFKELGESLKKITTWPDVGPSQKFTQSKLQREFKASLTEFQQLQKQALEKEKQSAQAARTALQDATSPSEERGDYGSHQLQEQEQLRLANQDEVDFQESLIIERESEIRNIEQSVGELNELFRDVAHMVHEQGAQLDIIEENVETTHDASRGAHINLKQASNYQKSARSKACILLLILAIVLVIIILAVVLD</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="578" mass="63279" checksum="31C4C3E70E45A217" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
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        </recommendedName>
    </protein>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063:SF60">
        <property type="entry name" value="LYSOPHOSPHATIDIC ACID:OLEOYL-COA ACYLTRANSFERASE 1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0808">Transferase</keyword>
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            <end position="52"/>
        </location>
    </feature>
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            <end position="81"/>
        </location>
    </feature>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="40228" checksum="9A80755085683F21" modified="2014-04-16" version="1">MEKYSQFRDKGTAIAPFLPVPPPPVGILWYPIYLFLFCVRTPFVIAFSLLYFFGLEFIPVGRRLKYVVLWLMLGIPGVWWVDLQVDGVKRGQLYSAKNHLPKAGTIVASSFTSPLDPLYLAGIFQPIFTKSYPHLRRVERITLFRAILLAFSPPSLTPNDPSKLITLKQLISENPDRIICVFPETTTTNGRGILPLCPSLLSADGKTKIYPVNLRYTPQDVTTPVPGGYFSWFWRLLSKPSHQMRVRIASRVYNSTNQDSPAKAKSDLHESKATTSGYDANIFEQPDFKDGFIGTNGGAGDGMDVDAGGADDGREISPEEQKVLERVAEDLARLGRVKRVGLSVETKIEFLKVWGSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5G4</accession>
    <name>W6Z5G4_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="3 4">
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963989">
        <property type="protein sequence ID" value="EUC45195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688279.1">
        <property type="nucleotide sequence ID" value="XM_007690089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5G4"/>
    <dbReference type="GeneID" id="19124665"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5593"/>
    <dbReference type="HOGENOM" id="CLU_534177_0_0_1"/>
    <dbReference type="OrthoDB" id="3690364at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="54"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="510" mass="57123" checksum="A9BFE0C06D2C66D4" modified="2014-04-16" version="1">MRRTHVAGELQKGKSAVSSKNIPSDFAQSILATTKDDHEPPENPEGASTARELQASLSRLPEELLLYILQHLKDQKDDLARLCRVNRRCKRISQELLYGTVGGVRPHHGDAYAISRWPALARNVRMLVYAFTDSEDKKSEREAFLCVLKNGHDIRWITLGVDLAKTDDNDELASTRTTTAGWLRLFNQAIAPSLEPRNRFSKLTHLCIKARRLASRNFPIESLSSLFRLPSLLHLQLDGFHQTTPFKSWPISPSTSPIKELFLHRAMLDITALSHLVTSIHSLEHFEYNFHTAPWEPFAADSNPLSIFPEHSWSQLGTALQHHRTCLERLSLSDASDAEIVKTVYPEGHDFGVLGSLSNFDCLHSMACPLKIFVNVDTAGEGELLALLPPRLEAFSTIVREKEADEAAGHVALITSTRDAVKARGLEVSVYFQYIRKCQVRTSQRLSDAAKRAVETGVVLFFKGGEKDEQTWVQGRQNGEEEDEDGEEEDGSMDGEENVDDDIMDDGDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5J4</accession>
    <name>W6Z5J4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_7623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964047">
        <property type="protein sequence ID" value="EUC42834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690615.1">
        <property type="nucleotide sequence ID" value="XM_007692425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5J4"/>
    <dbReference type="STRING" id="930090.W6Z5J4"/>
    <dbReference type="GeneID" id="19125338"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7623"/>
    <dbReference type="eggNOG" id="KOG3086">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038085_0_0_1"/>
    <dbReference type="OrthoDB" id="417112at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="333" mass="36413" checksum="C716AEE476E71137" modified="2014-04-16" version="1">MVTRKASHAGSWYTDNGQLLSQQLDDWLGAVPASTTPIGSASSQKGQVSIPTPNARAIIAPHAGYSYSGPAAAWAYKSADWANAKRVFLLGPSHHYYLSGAATTGCDKYHTPLGDLTVDTNLVQAIQQEWDLEIMSKRTDEDEHSLEMHLPYIYKMLSLKNKDFQSNPSSVPLVPIMVGNTDAAAEARYGSLLAPYLADSTNIFVISSDFCHWGSRFRYTYYQPPNGAAATQLKSSSRVPSDYPIHEGIAAVDHESMDAIETGSHRKFLDQLRKTGNTVCGRHPIGLFMAAVESAEALEEGKGIFSFLRYERSSLVEDLQDSSVSYCSAFAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5S3</accession>
    <name>W6Z5S3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">biotin synthase</fullName>
            <ecNumber evidence="3">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_36893</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="14">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="3"/>
    <dbReference type="EMBL" id="KI963986">
        <property type="protein sequence ID" value="EUC45315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688130.1">
        <property type="nucleotide sequence ID" value="XM_007689940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5S3"/>
    <dbReference type="STRING" id="930090.W6Z5S3"/>
    <dbReference type="GeneID" id="19123135"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36893"/>
    <dbReference type="eggNOG" id="KOG2900">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033172_3_2_1"/>
    <dbReference type="OrthoDB" id="2414104at2759"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000011">
        <property type="entry name" value="Biotin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="BIOTIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976:SF2">
        <property type="entry name" value="BIOTIN SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01060">
        <property type="entry name" value="BATS_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00272">
        <property type="entry name" value="biotin_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01278">
        <property type="entry name" value="biotin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="93"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
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    <sequence length="405" mass="44464" checksum="7C658699B02F84B1" modified="2014-04-16" version="1">MAQRMLLRASGPRRVYYGFTTRSFSTVLDTPVDPGTQQIRLTTPRTTVFENALNAKAPRTNWTKEEISEIYNTSLIDLTYASASVHRRFHDPAAIQMCTLFNIKTGGCSEDCSYCAQSSRYDTGLKATKLSSVESVLEAARIAKENGSSRFCMGAAWRDMRGRKTNLKNIKEMIKGVRGMGMEACVTLGMVDAAQAKELKDAGLTAYNHNVDTSREHYPSVITTRTYDERLNTIKNVQEAGIHVCTGGILGLGEKARDHVGLIHTVATLPAHPESFPVNALVPIKGTPLGETQAISFDAILRTIATARLVLPTTIIRLAAGRHTMREEKQILCFQAGANAVFTGEKMLTTACNGWEEDKAMFEKWGLRPMKMEETIGEKRKVPGQEEAEAVVAAAEKEATVQALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="11">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12 13">ATCC 44560</strain>
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    </reference>
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        <subcellularLocation>
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        <property type="entry name" value="Haloacid_Dehalogenase"/>
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    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
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    </feature>
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    </evidence>
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    </evidence>
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        <source>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1107" mass="122454" checksum="29B96507306E83DA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z746</accession>
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        <recommendedName>
            <fullName evidence="8">L-2-hydroxyglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="7">1.1.99.2</ecNumber>
        </recommendedName>
    </protein>
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        <name evidence="10" type="ORF">COCMIDRAFT_101015</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2</text>
            <dbReference type="Rhea" id="RHEA:21252"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:16782"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.1.99.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the L2HGDH family.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.2" evidence="7"/>
    <dbReference type="EMBL" id="KI964031">
        <property type="protein sequence ID" value="EUC43379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690121.1">
        <property type="nucleotide sequence ID" value="XM_007691931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z746"/>
    <dbReference type="STRING" id="930090.W6Z746"/>
    <dbReference type="GeneID" id="19117787"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101015"/>
    <dbReference type="eggNOG" id="KOG2665">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024775_1_0_1"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047545">
        <property type="term" value="F:(S)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104:SF4">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="9">
        <location>
            <begin position="38"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC43379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="408" mass="43999" checksum="D00456DD6D5F8000" modified="2014-04-16" version="1">MLSLRAAQRATLKVPKHSRTLHRSFASTARLDADFTHAVIGGGVVGLAIARKLQSRPSTSTVLIEKHGTAGTETSSRNSEVIHAGLYYGPSSRKTKLCIRGKTLLYELCAQQGIPHRNTGKWIVAQDAEQMEALEKVHDFAQSVGVPTRFLNKQEASTREPEVRAEAGVLESPSTGIIDSHSLMQYLEGDFENNGGICAFNSPVTSITPIDSGRRGWEITTTTAEETSTITAETFINAAGLYAIPLANTILPPSRQKAAFYAKGSYFSYSSSRPRTSTLIYPAPIPGHAGLGTHLTLDLAGRIRFGPDVEWTDSPSDYTPNTKNLAAAIADIKTYLPGVQADAIAPDYVGIRPKLGKLAATNGGKGFQDFYIEKEEGFEGWVNLLAIESPGLTSCLAIAEEVEGLLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z780</accession>
    <name>W6Z780_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_4977</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the VPS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687601.1">
        <property type="nucleotide sequence ID" value="XM_007689411.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z780"/>
    <dbReference type="GeneID" id="19124450"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4977"/>
    <dbReference type="eggNOG" id="KOG1809">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000135_0_0_1"/>
    <dbReference type="OrthoDB" id="428159at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056748">
        <property type="entry name" value="VPS13-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056747">
        <property type="entry name" value="VPS13-like_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017148">
        <property type="entry name" value="VPS13_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009543">
        <property type="entry name" value="VPS13_VAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25037">
        <property type="entry name" value="VPS13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25033">
        <property type="entry name" value="VPS13_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25036">
        <property type="entry name" value="VPS13_VAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037235">
        <property type="entry name" value="VPS13_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="3 4" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="domain" description="VPS13-like middle region" evidence="7">
        <location>
            <begin position="1120"/>
            <end position="1903"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding" evidence="8">
        <location>
            <begin position="1972"/>
            <end position="2545"/>
        </location>
    </feature>
    <feature type="domain" description="Intermembrane lipid transfer protein VPS13-like C-terminal" evidence="9">
        <location>
            <begin position="3066"/>
            <end position="3171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="561"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="842"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="889"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1063"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1392"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1582"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1754"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="564"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="582"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="859"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1582"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1783"/>
            <end position="1794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC45840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="3197" mass="359261" checksum="7FD9E1A3C97ADF78" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z795</accession>
    <name>W6Z795_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_89546</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685856.1">
        <property type="nucleotide sequence ID" value="XM_007687666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z795"/>
    <dbReference type="STRING" id="930090.W6Z795"/>
    <dbReference type="GeneID" id="19127500"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89546"/>
    <dbReference type="eggNOG" id="ENOG502S2AR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008243_1_0_1"/>
    <dbReference type="OrthoDB" id="9368434at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Zinc_finger_trans_reg"/>
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        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
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        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
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    </dbReference>
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        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="429"/>
            <end position="456"/>
        </location>
    </feature>
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            <begin position="1"/>
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        </location>
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        </location>
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        </location>
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            <begin position="518"/>
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        </location>
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            <begin position="147"/>
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        </location>
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            <begin position="531"/>
            <end position="540"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="763" mass="85826" checksum="EA0D99AF5ABD384F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7W6</accession>
    <name>W6Z7W6_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_89056</name>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889786" description="Transcription factor domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="31053" checksum="4E5ABB54AEF07BA6" modified="2014-04-16" version="1">MAEIGFKHPYVLHLMLAFTALHLAYSRPHRKEEYVAMADRHYERALVLVTPQITNLNPENSDAILLAEQLICFISWGRGPQPGEYLAFGRDKKSDWLVMFRGIRATSSNVELLQSERPSAAAANGILPPLPPLEEPEDYEKQLESLMAFVRSMSKDTPGYRNDVEAVYILREMYENRYRSGEGEYHVSFGWLYRVSDDFLERLQQHDPVPMIIYAHFVVLVRILEQFWYMQGWTHHIVSGIWDLLPTEYRAWLDWPIKRIGWIRP</sequence>
</entry>
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    <accession>W6Z866</accession>
    <name>W6Z866_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">SIS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_36382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z866"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_36382"/>
    <dbReference type="eggNOG" id="ENOG502RXQH">
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    </dbReference>
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    <dbReference type="OrthoDB" id="1872003at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38418">
        <property type="entry name" value="SUGAR ISOMERASE, KPSF/GUTQ (AFU_ORTHOLOGUE AFUA_6G08860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38418:SF2">
        <property type="entry name" value="SUGAR ISOMERASE, KPSF_GUTQ (AFU_ORTHOLOGUE AFUA_6G08860)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="99"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="294" mass="30644" checksum="1F6BBEC6ADD9ED86" modified="2014-04-16" version="1">MAEPLADTPPLSSSASASASPSPSPSPASSPSPSPVSLKRKRAPSDAQPLTPPLSADDPKGTHLLSRAVHVLSTAATALSQVTFLYQSDHVARHGLLQAVEVITKNSEAGGKLIVCGVGKSGLVGRKIVATMKSLGIASSFMHAAEALHGDLGDIRKNDAVMFISYSGKTAELVALLDHIPSHTPILAITSHTKPSECPILRNRPCSILLPAPIHELEEVSFGVCAPTTSTTVTIAVGDMLALTIAEAMHQEDTKVVFRRNHPGGAIGAKTRRIEEETDTQTNKCTGLVTPPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z875</accession>
    <name>W6Z875_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nuclear cap-binding protein subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">20 kDa nuclear cap-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_10106</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RRM NCBP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964227">
        <property type="protein sequence ID" value="EUC39896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693580.1">
        <property type="nucleotide sequence ID" value="XM_007695390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z875"/>
    <dbReference type="STRING" id="930090.W6Z875"/>
    <dbReference type="GeneID" id="19117793"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10106"/>
    <dbReference type="eggNOG" id="KOG0121">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070952_1_1_1"/>
    <dbReference type="OrthoDB" id="201398at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12240">
        <property type="entry name" value="RRM_NCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000399">
        <property type="entry name" value="Nuclear cap-binding protein subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027157">
        <property type="entry name" value="NCBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034148">
        <property type="entry name" value="NCBP2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847">
        <property type="entry name" value="20 KD NUCLEAR CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="48"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC39896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="168" mass="19388" checksum="0432BD3D1EA52443" modified="2014-04-16" version="1">MPALRSTIDRLDKPSSYATAKKRRRDRNTRDEDRARSPSPEDKLKDATTLYVGNLSFYTTEEQIHELFSKCGEIKRLVMGLDRFQKTPCGFCFVEYYTHQDALDCMKYIGGTKLDERVIRTDLDEGFTEGRQYGRGKSGGQVRDEYRAEYDPGRGGYGRAVDEYHEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8C1</accession>
    <name>W6Z8C1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alcohol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_34549</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685501.1">
        <property type="nucleotide sequence ID" value="XM_007687311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8C1"/>
    <dbReference type="STRING" id="930090.W6Z8C1"/>
    <dbReference type="GeneID" id="19122581"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34549"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_1_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="9">
        <location>
            <begin position="16"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="356" mass="37579" checksum="1C891386E108DF79" modified="2014-04-16" version="1">MEVPTTQKAAVKQGSGDKTTIVIKDVPVPAPSPDEVLVKINYTGLCATDKSLLYDEWPITMTEATNGICGHEGAGTVVAVGSNVKDLWQIGNRAGIKWVASVCRRCEFCTNGQDECACPKLRNSGFHVAGTFQEYCVADGHYATKLPDGVKDEEAGPIMCGGVTAYVACKRSNVRPGQWVVIPGAGGGLGHFGIQYAKHMGMRVIAIDGGDAKRDLCLKLGAEKFIDFTTCADITSEVLKITQYGAHGILVFPATNAAYESAPHLLRPGGTMVCVGLPKDPNFVAGASPLLLCAKKLNVVGSVTGTLKEVEEALDFTARGLVRPILTYGGLEDIDRFFADMGAGKLAGRAVIKVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8F4</accession>
    <name>W6Z8F4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_25687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687209.1">
        <property type="nucleotide sequence ID" value="XM_007689019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8F4"/>
    <dbReference type="GeneID" id="19120807"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25687"/>
    <dbReference type="HOGENOM" id="CLU_2249625_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887263" evidence="2">
        <location>
            <begin position="26"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="104" mass="10862" checksum="6933E04F0AE63DCA" modified="2014-04-16" version="1">MLPKVLPLTAVTFCLYSLLLSSVIACSSDCKAAVRTTKLPPTPAPAPAPAPAPTPTPTPVPIPTSNGAWQSHPMLSPSPLAICTASLPNTNQGRVTRYRQVCWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z991</accession>
    <name>W6Z991_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_2889</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685209.1">
        <property type="nucleotide sequence ID" value="XM_007687019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z991"/>
    <dbReference type="GeneID" id="19121398"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2889"/>
    <dbReference type="eggNOG" id="KOG1012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002125_2_0_1"/>
    <dbReference type="OrthoDB" id="419768at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04041">
        <property type="entry name" value="C2A_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21676">
        <property type="entry name" value="SMP_Mug190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057349">
        <property type="entry name" value="C2_Mug190_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037767">
        <property type="entry name" value="C2A_Mug190-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348:SF3">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25331">
        <property type="entry name" value="C2_Mug190_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="250"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="475"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="664"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="114"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="638"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="700"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1058"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="705"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1085"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1103"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1144"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1163"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1181"/>
            <end position="1197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC48277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1244" mass="139282" checksum="DC7D302A02A46AD7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9F2</accession>
    <name>W6Z9F2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_34225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685155.1">
        <property type="nucleotide sequence ID" value="XM_007686965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9F2"/>
    <dbReference type="STRING" id="930090.W6Z9F2"/>
    <dbReference type="GeneID" id="19122518"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34225"/>
    <dbReference type="eggNOG" id="KOG2111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025895_0_0_1"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="247"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="392" mass="42701" checksum="7F54721C8943FF8E" modified="2014-04-16" version="1">MNTRPILDSDTGPFVLSASFNADCSHFSVALETGFRVFSSTTCEERIAREVGGGIGCAEMLGNKSYIALVGGGKQPKYPQNKVRPEDSDWIWVEKTDIIFKVQIWNDKTERFTTSVEFKTPIQRVRLSQTHMVVALLNSVCIYKMKVPPVKTAEYETVNNPFGLLELGSSIVAFPGRAAGQVKIYDLNTGNVSIIPAHESPLRAIGISRSCDLIATASEQGTIIRLWSFPSCTKLAELRRGVDPAAVFSLAFSPDGSTLAVTSDKSTLHIYDLKTATAAAQADPAQHKYGILSKIPLLPRQFSDTYPTATVKFEMGDEPTSWGPHGKSATLSVGIPGVPGGRPTKGLIGWLDDQTVLVLGAGQDARWERFIMGVDDKGKKCLVANGWRRYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9Y5</accession>
    <name>W6Z9Y5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964158">
        <property type="protein sequence ID" value="EUC40521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692955.1">
        <property type="nucleotide sequence ID" value="XM_007694765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9Y5"/>
    <dbReference type="GeneID" id="19119274"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108591"/>
    <dbReference type="HOGENOM" id="CLU_2782665_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="69" mass="7730" checksum="9AB4502D51067BA4" modified="2014-04-16" version="1" fragment="single">FFSRRIDLIRYIANGWKKKSKNGISCDPRLSMSARSSCNGSRRRQARRLRKGVRRAVISASTGAMNSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA12</accession>
    <name>W6ZA12_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_91700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686650.1">
        <property type="nucleotide sequence ID" value="XM_007688460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA12"/>
    <dbReference type="GeneID" id="19127932"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91700"/>
    <dbReference type="HOGENOM" id="CLU_1119999_0_0_1"/>
    <dbReference type="OrthoDB" id="3676551at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="248" mass="28191" checksum="CCA402314C1073D4" modified="2014-04-16" version="1">MSLPRPCPLTTTHRQTSSEDDVTADSDFSESDSDWGFDSDDDEDENGDVDEECFYINAIISVPGPYTLSWDCSSSLLWSKSLVQHGEFEAADAILLAFVVDVAMKLYIVDGINYSVLNILDTSQLVWTVLSIIHNSIYKRVSCCGWSKGDVIQTVESFFLAAAPGLHRIRERFDIAFLQKILDPYTKLLFAKKLILHENFTPNTGKIAKVYRWVYGEPPELVLFNDMEDGEPPSQRPINIRQWVFEYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA60</accession>
    <name>W6ZA60_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_86932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684871.1">
        <property type="nucleotide sequence ID" value="XM_007686681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA60"/>
    <dbReference type="GeneID" id="19126955"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86932"/>
    <dbReference type="HOGENOM" id="CLU_2960386_0_0_1"/>
    <dbReference type="OrthoDB" id="3659212at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="59" mass="6872" checksum="A18CD5A9E66BF382" modified="2014-04-16" version="1">MRQTPTWPMMPADPRLSSLGPRTVDCGSLIEMRQWLSGALAQRYCHQLNQRDFRRLNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA71</accession>
    <name>W6ZA71_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Elongation factor 1-alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_41086</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964151">
        <property type="protein sequence ID" value="EUC40616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692866.1">
        <property type="nucleotide sequence ID" value="XM_007694676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA71"/>
    <dbReference type="STRING" id="930090.W6ZA71"/>
    <dbReference type="GeneID" id="19123995"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41086"/>
    <dbReference type="eggNOG" id="KOG0052">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_3_5_1"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000003">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000005">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000211">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_A">
        <property type="entry name" value="EF_Tu_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004539">
        <property type="entry name" value="Transl_elong_EF1A_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00483">
        <property type="entry name" value="EF-1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008969">
        <property type="entry name" value="PRK12317.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="10 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="5"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC40616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="459" mass="50080" checksum="A3EA98315643D900" modified="2014-04-16" version="1">MGKEKIHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPRYYVTVRCIDAPGHRDFIKNMITGTSQADCAILIIAAGTGEFEAGISKDGQTREHALLAYTLGVKQLIVAINKMDTTKWSEDRYQEIIKETSNFIKKVGYNPKHVPFVPISGFNGDNMIEASTNCPWYKGWEKETKSKSTGKTLLEAIDAIDPPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGIIKAGMVVTFAPAGVTTEVKSVEMHHEQLTEGVPGDNVGFNVKNVSVKEIRRGNVAGDSKNDPPKASESFNAQVIVLNHPGQVGAGYAPVLDCHTAHIACKFSELLEKIDRRTGKSVENSPKFIKSGDAAIVKMVPSKPMCVEAFTDYPPLGRFAVRDMRQTVAVGVIKSVAKVDKAGKVTKAAVKASKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB80</accession>
    <name>W6ZB80_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_97568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688811.1">
        <property type="nucleotide sequence ID" value="XM_007690621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB80"/>
    <dbReference type="GeneID" id="19129086"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97568"/>
    <dbReference type="eggNOG" id="ENOG502SSKF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1310339_0_0_1"/>
    <dbReference type="OrthoDB" id="3800879at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="224" mass="26049" checksum="1CA7F41963887CB2" modified="2014-04-16" version="1">MCLVKVKQEEDHIVPYRVVQRARSPPRRRVSRHSRDIERRYSRSEVVRDSPPRPSSSYIAVPSPKPLQIPAPQPVPVFVQPSPPPPPPPAPMPAPPPPPSHISSHHTSHHGGAHYVEVSPRSSITSHTSSLDDRSEYVYREREVRRERQRAYSPDNPRYEHYRYVEPASSESDHYERYQTRDRSRQRSRSRAGYDDSRGGYRETTNMRVSIGENDGRRRRDYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB86</accession>
    <name>W6ZB86_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_2125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684383.1">
        <property type="nucleotide sequence ID" value="XM_007686193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB86"/>
    <dbReference type="GeneID" id="19120027"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2125"/>
    <dbReference type="HOGENOM" id="CLU_1189817_0_0_1"/>
    <dbReference type="OrthoDB" id="3664019at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="200" mass="22376" checksum="678813EBB7892853" modified="2014-04-16" version="1">MSLETKVGLAMIPIAVGLCAWGLVLLILWRRRKTHQSHHRITSFTAFGPEKANSPLLPSPSSSLSSSTRSRRIFTMAAFYSRDNKQGMSVMRPTTPPPFNSPVERAKTDSNPDSPIDGGSPFRLRPGEARKSLGSEISELWPSPPPTAWARRLDILEQLPESRFGRDMTGPRLKRSENRKSLRDARDVTRPSMGDDWPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBC9</accession>
    <name>W6ZBC9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_85657</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684471.1">
        <property type="nucleotide sequence ID" value="XM_007686281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBC9"/>
    <dbReference type="STRING" id="930090.W6ZBC9"/>
    <dbReference type="GeneID" id="19126702"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85657"/>
    <dbReference type="eggNOG" id="KOG1965">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005912_5_2_1"/>
    <dbReference type="OrthoDB" id="196264at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF187">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="234"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="354"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="49"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="484"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="496"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="568"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC49107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="653" mass="71360" checksum="A631601E8197AE22" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBH3</accession>
    <name>W6ZBH3_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_33415</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the REI1 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
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        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
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        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
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        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
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            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="305"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="499"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="389"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="555" mass="62041" checksum="6D231B99808F524F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBK4</accession>
    <name>W6ZBK4_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_85403</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684341.1">
        <property type="nucleotide sequence ID" value="XM_007686151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBK4"/>
    <dbReference type="STRING" id="930090.W6ZBK4"/>
    <dbReference type="GeneID" id="19126659"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85403"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_2_1"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF34">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="98"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="544" mass="58517" checksum="6B2F87DEFEA0B85C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBU1</accession>
    <name>W6ZBU1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glutamine--fructose-6-phosphate transaminase (isomerizing)</fullName>
            <ecNumber evidence="4">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_9085</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="4"/>
    <dbReference type="EMBL" id="KI964116">
        <property type="protein sequence ID" value="EUC41181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692301.1">
        <property type="nucleotide sequence ID" value="XM_007694111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBU1"/>
    <dbReference type="STRING" id="930090.W6ZBU1"/>
    <dbReference type="GeneID" id="19127767"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9085"/>
    <dbReference type="eggNOG" id="KOG1268">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_5_2_1"/>
    <dbReference type="OrthoDB" id="15235at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00528"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00714">
        <property type="entry name" value="GFAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000001">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047084">
        <property type="entry name" value="GFAT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001484">
        <property type="entry name" value="PRK00331.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="11">
        <location>
            <begin position="2"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="12">
        <location>
            <begin position="371"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="12">
        <location>
            <begin position="542"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC41181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="693" mass="77175" checksum="2CAF8622D8637281" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCA4</accession>
    <name>W6ZCA4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tubulin-tyrosine ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_24749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686076.1">
        <property type="nucleotide sequence ID" value="XM_007687886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCA4"/>
    <dbReference type="STRING" id="930090.W6ZCA4"/>
    <dbReference type="GeneID" id="19120633"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24749"/>
    <dbReference type="eggNOG" id="KOG2157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031301_0_0_1"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027746">
        <property type="entry name" value="TTL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551:SF1">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="471" mass="52877" checksum="9B74CC9C9567E469" modified="2014-04-16" version="1">MASSGSKIGDKIYALINYEDLYVQPLILSALEKRLPTSSYELITSLSQLPTPSSPLLQFVQYESIDFDHLMEYSSTSLANAYVIRKALIRKHYLSTTIANWITKYPDSVLKKHVKPSVEFEVDYAEFLDDALVEAWELKESWARNEELGDDEDGASSSKKEWWILKPGMSDRGQGIRLFSSEQELTEIFEEWDPDSDDEDEEEDARSDSNAQQLKIEKDEDNGIITSQLRHFIAQPYIHPPLLLTPPNNPTSDLRKFHIRTYILAAGALKLYVYKPMLALFAAHPYLPPWSADVEPNSQKAMRAHLTNTCLQDSGDREGSVGLFWDLPDSLPAQPDFSGSSNSEGGDAERKVNVPSNWKDAIFQQICDITGSTFEAAARGMSIHFQPLPNSFEVFGLDFMVGLDEETGGLNTWLLEVNAFPDFRQTGSDLQGLVNGLMEGVVEKGIKPFFGLEGAENEDMVEVLNVDLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCJ7</accession>
    <name>W6ZCJ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_84388</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684038.1">
        <property type="nucleotide sequence ID" value="XM_007685848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCJ7"/>
    <dbReference type="STRING" id="930090.W6ZCJ7"/>
    <dbReference type="GeneID" id="19126458"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84388"/>
    <dbReference type="eggNOG" id="KOG3030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021458_0_2_1"/>
    <dbReference type="OrthoDB" id="10030083at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF84">
        <property type="entry name" value="PHOSPHATIDIC ACID PHOSPHATASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="116"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="327" mass="37230" checksum="05A0A051BBAAD2D1" modified="2014-04-16" version="1">MLAPGKHHWLRPGYYNTPSFRQICRDSWLNIFTGTLCVILAILLWRLCPPIIPHYLPYFEGVETHPIGLKYSQPLREEYINTIMMAAISFLVPSSIMLVMNLRVLRDYYNWDASFTGLSYALSTSTLFSCIIKVLIGGPRPNFYEICRPAAYLLEPTAPHMWSIVQYYPVSQLCTNTDKFSLNEAQKSFPASHASSAFAGFVFLALWLSAQYKTFGRSRLDTKHHNPVTETVLHDPKSGLKILSGRYFDAVPHWKIIIFSIPLWVAVALSLSKLRDGWHHPVDVVCGACIGTFFAVVAYKMVFWSVWDARDNHVPRRHVDGAVESRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCN4</accession>
    <name>W6ZCN4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Domain of unknown function at the cortex 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_8809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964100">
        <property type="protein sequence ID" value="EUC41496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691979.1">
        <property type="nucleotide sequence ID" value="XM_007693789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCN4"/>
    <dbReference type="GeneID" id="19127198"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8809"/>
    <dbReference type="eggNOG" id="ENOG502RXNE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047849_0_1_1"/>
    <dbReference type="OrthoDB" id="2119945at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013897">
        <property type="entry name" value="Duc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826:SF2">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08588">
        <property type="entry name" value="Duc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Domain of unknown function at the cortex 1" evidence="2">
        <location>
            <begin position="9"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="325" mass="36847" checksum="FBC0F148947B0F93" modified="2014-04-16" version="1">MTSHEQYMLRVTAGPTYDVSKHEAVPVNREKPVSILSDHIDAKVHMRIKDYRGLPEGSPSTSPYFSTPQHPYDRYSISFSFTPKQDIAGDKLVFGNDFDHPIRDRLPPLFDKAFGIVKWWIDPGLDGDVYADEPYLYGALLSSINVFRIGSKKDEHSEDKGAEGEAQTEDDVEKSGSEGEVVVYEEGADGDGAAIRKEKSIPDKAGARQKFFLSEQNRKDFTFEAGREYQCDFFNPYLDFNEFALKIGYGLPNISMIRHWDGQPLRYVLKNRETNQELFVVVIELLPTEQAKKEGVEDAEEKFAEAHGKEGEKEAEKDSKDDDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCX0</accession>
    <name>W6ZCX0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_34716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685680.1">
        <property type="nucleotide sequence ID" value="XM_007687490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCX0"/>
    <dbReference type="GeneID" id="19122625"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34716"/>
    <dbReference type="HOGENOM" id="CLU_2960388_0_0_1"/>
    <dbReference type="OrthoDB" id="10287085at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="59" mass="6687" checksum="E47C0550DFA3994C" modified="2014-04-16" version="1">MTGVPAAPMCNHYLRRRLSTFLLCCAPWPSFGEMLSNSESITWSQPRANDVQRRTVNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD12</accession>
    <name>W6ZD12_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_34603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685577.1">
        <property type="nucleotide sequence ID" value="XM_007687387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD12"/>
    <dbReference type="STRING" id="930090.W6ZD12"/>
    <dbReference type="GeneID" id="19122593"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34603"/>
    <dbReference type="eggNOG" id="ENOG502S4IP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_621369_0_0_1"/>
    <dbReference type="OrthoDB" id="3798666at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887382" evidence="2">
        <location>
            <begin position="21"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="463" mass="49422" checksum="0BF096E9A2C962FF" modified="2014-04-16" version="1">MAPARNSVLVLLGLAISIRAAPAGFQERQGEINPPQQSVSWDTGNPEPTEGPYEPINPPKPTDQISLGKPSFWISWETSEPEPTPEPEYPPPKPSDQISIGNPSYSISWDGEGPGASTPTPVPTPTPKPTPEYPSVTPSPSVPTSSSTSKQASSSVPTSKSISTGKVSSTRKPGYPPWNPWPPRPTTFKSTTRPKPSSTQTPTSTKEVQTSSPPPQYSISWNMEQRNVKPTSTKKPTPTSTKKPTPKPTPKPTSKVTPKPTSKPTSKPTSKSTPPSTSKATPTPTPTSTSKAASTPTPTPTPKPTPTPTPEPDTTSYAPPDITLGPPDFSISWGKRTPEPTSAPFPDEEDPFPEDPEEEDPDFPLPPPTLPTPPNEISIQPPTATVIWGKRQEDDDDDDDFPPPSIPSQVNSVGVEQPTATVIWGKKRQDDGGDDDDDFPPPSTPTQHDSAGIEQPTATVIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD35</accession>
    <name>W6ZD35_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61</fullName>
            <ecNumber evidence="1">2.1.1.220</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(m1A58)-methyltransferase subunit TRM61</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_3350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.220" evidence="1"/>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685733.1">
        <property type="nucleotide sequence ID" value="XM_007687543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD35"/>
    <dbReference type="STRING" id="930090.W6ZD35"/>
    <dbReference type="GeneID" id="19122340"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3350"/>
    <dbReference type="eggNOG" id="KOG2915">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029873_1_0_1"/>
    <dbReference type="OrthoDB" id="5585464at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160107">
        <property type="term" value="F:tRNA (adenine(58)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.330.20:FF:000003">
        <property type="entry name" value="tRNA (Adenine(58)-N(1))-methyltransferase, mitochondrial isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049470">
        <property type="entry name" value="TRM61_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133:SF1">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08704">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 C-terminal" evidence="9">
        <location>
            <begin position="207"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="326"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="329"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="402" mass="44724" checksum="F8CFDFF993C59A83" modified="2014-04-16" version="1">MRHSPLHLLQRLPLKTPARYFTKGDLVLLREKKDTHDGRLVKLQASKSTGTHLGVVQHADIIGRQPRQIVQSNKGASYRIHDPTLAEYVRLTPRLVTPIYPSDANLIISLFDINVDRPSAGLSTDPPLEILEAGTGHGALTLHLSRAIHAANPPIPRAPAHSGSEDGPEDAVYLGESVSDLQHSYLESWKQSRRAILHTLDISPKYSQHAKKIVEGFRHGMYAANVDFHVGDVSDWISKQRRTRRTQQPFLSHVFLDLPNPTHHLPNVAPVLHVNGLLAVFNPSITQVAECVEAIREQKLPYLLEQVVELGAGTIREWDVRAVKPRATLQKSSAEQTSAPSGNRSQDSETEQASRDGELEAALNKQKEEEEEKWAMVCRPKAGQQVIGGGFLGLWRRMEQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDW3</accession>
    <name>W6ZDW3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trehalose-6-phosphate synthase</fullName>
            <ecNumber evidence="6">2.4.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">UDP-glucose-glucosephosphate glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_88118</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-glucose 6-phosphate + UDP-alpha-D-glucose = alpha,alpha-trehalose 6-phosphate + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="2.4.1.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="6"/>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685333.1">
        <property type="nucleotide sequence ID" value="XM_007687143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDW3"/>
    <dbReference type="STRING" id="930090.W6ZDW3"/>
    <dbReference type="GeneID" id="19127205"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88118"/>
    <dbReference type="eggNOG" id="KOG1050">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002351_7_2_1"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000007">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000035">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012766">
        <property type="entry name" value="Trehalose_OtsA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02400">
        <property type="entry name" value="trehalose_OtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF106">
        <property type="entry name" value="BCDNA.GH08860"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="497"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC48113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="520" mass="58381" checksum="A7A3F35885DF35E5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE23</accession>
    <name>W6ZE23_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RlpA-like protein double-psi beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_82947</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683477.1">
        <property type="nucleotide sequence ID" value="XM_007685287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE23"/>
    <dbReference type="STRING" id="930090.W6ZE23"/>
    <dbReference type="GeneID" id="19126157"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82947"/>
    <dbReference type="eggNOG" id="ENOG502S2E4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_956800_0_0_1"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887410" description="RlpA-like protein double-psi beta-barrel domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="30895" checksum="74FE5F450B8A65B6" modified="2014-04-16" version="1">MKASTVLASLLFGSIAAAAPVDKRALVYKTEVVTEVVVIYTTVYGDEPTPTPSAVSSSSTTAAAFYEQKKPVPSSTPAALPAYTPAPAPASSAPAPPVYTPPVEEKPKPSPTPSPEPQPEPQPSPSPEPQPEPQPSPSQAPAPAPQPEEVYTPAPAPSPTPSPSPTPAPAPAPAPAKYPTTESSSSGGDVHQDVDITVYDNTGAAGACGEPLTDDMMVVAIAKGAWNAKGGSTYDVMTGASSNPWCGAKINIEYEGKSCQATIMDLCPGCEGLYDIDLSRAAWKALGITETTRLKANWSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEL8</accession>
    <name>W6ZEL8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">D-serine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-serine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_8377</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the conversion of D-serine to pyruvate and ammonia. May play a role in D-serine detoxification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13977"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="EC" id="4.3.1.18"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:13978"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DSD1 family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.18" evidence="11"/>
    <dbReference type="EMBL" id="KI964078">
        <property type="protein sequence ID" value="EUC41971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691497.1">
        <property type="nucleotide sequence ID" value="XM_007693307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEL8"/>
    <dbReference type="STRING" id="930090.W6ZEL8"/>
    <dbReference type="GeneID" id="19126324"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8377"/>
    <dbReference type="eggNOG" id="ENOG502QWI8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031639_0_0_1"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036088">
        <property type="term" value="P:D-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000016">
        <property type="entry name" value="D-serine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0216">Detoxification</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="14">
        <location>
            <begin position="333"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00066349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00075219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC41971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="467" mass="50227" checksum="A7A87EB5B4DD0694" modified="2014-04-16" version="1">MSELFTLQNYPLPSSSSLAAQFVGKTLNELPTPAVVLDRALIKRNCNAMLNVCKELGVGFRAHVKSHKTAELSKLQVGEEGAANFIVSTIIEAEKLAELVVKEQGKGRDASILYGVPVPQSGIPRLIALAEKLKPRSINLIIDNQDAFLKLAQRLAVSSSQVELGIFIKIDTGYERAGIKTSSPSFPTLVSTVVSKTQETGSKCFLQGFYSHFGHSYAGSSEDDAANGLMEELVGLEAATKAVPASFAGKLVLSVGATPTATAAQNMLSSASPRVREFQTVLSRLQAQHLVELHAGVYPLLDCQQVATHARPPTSSSAEPRPAFQPLSKSNIGIRMLLEVTSVYNERAKPEALVSAGSLAMGREPCKSYAGWGIVTPDLGNSSAQHIYDEQAGRTGWVVGRISQEHGILTWEGDKAACNELVIGDKVMIWPNHACVAGAGFGWYLVVDSEEGRGETVVDVWVRWRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF97</accession>
    <name>W6ZF97_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Organic hydroperoxide resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_87071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OsmC/Ohr family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684997.1">
        <property type="nucleotide sequence ID" value="XM_007686807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF97"/>
    <dbReference type="GeneID" id="19126979"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87071"/>
    <dbReference type="eggNOG" id="ENOG502S77G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106355_2_1_1"/>
    <dbReference type="OrthoDB" id="60422at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019953">
        <property type="entry name" value="OHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03561">
        <property type="entry name" value="organ_hyd_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33797">
        <property type="entry name" value="ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33797:SF2">
        <property type="entry name" value="ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="OsmC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="19273" checksum="8D32B8EFE214239C" modified="2014-04-16" version="1">MASRTFTPIFRQTLRVSQRKIVAAPCRRFLNTETAPNLYSARAKVVGARTGHVDGENLKVELTMAKVLGGAGDKGKTNPEELFAAGYGACFQSAMNASAASLGIKMPTTPEDSIVESTVELVGDMKELDLGLRVNLLVKVRGLSEQELEKVVNKAREVCPYSRATQGNVHTTIKCETM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFH9</accession>
    <name>W6ZFH9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_29141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964069">
        <property type="protein sequence ID" value="EUC42226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691263.1">
        <property type="nucleotide sequence ID" value="XM_007693073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFH9"/>
    <dbReference type="GeneID" id="19121446"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29141"/>
    <dbReference type="HOGENOM" id="CLU_1434232_0_0_1"/>
    <dbReference type="OrthoDB" id="3686254at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="192" mass="22023" checksum="25ADC66C45C575AD" modified="2014-04-16" version="1">MYGAPDAYACRLLIVLKPRAARATFLDLPGELRNQIYAYSIYPDLSSIFVANCTKPEHFGATILHLPIFRTCRQIRAETLSYLCATLQLGFLGIHSAVLFFSLAGKAASEIKSLFLIEPLCIGEEYTESKETVEQFLRALEAMRELSEIQVNNIGRLTPPDQKTWFWKFTKRLEKLQERRENLRFRSAWPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGQ4</accession>
    <name>W6ZGQ4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_102934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964053">
        <property type="protein sequence ID" value="EUC42666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690815.1">
        <property type="nucleotide sequence ID" value="XM_007692625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGQ4"/>
    <dbReference type="GeneID" id="19118188"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102934"/>
    <dbReference type="HOGENOM" id="CLU_2819378_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="55" mass="6094" checksum="0D7B6F4CE5A9E2FB" modified="2014-04-16" version="1" fragment="single">NTTKQKALSNQNIKILKRRRVVEVKSGGGDASPPAKPITKTTTRGRSMRLPSKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHS8</accession>
    <name>W6ZHS8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_79348</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the heterotrimeric canonical replication protein A complex (RPA).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682261.1">
        <property type="nucleotide sequence ID" value="XM_007684071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHS8"/>
    <dbReference type="STRING" id="930090.W6ZHS8"/>
    <dbReference type="GeneID" id="19125459"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79348"/>
    <dbReference type="eggNOG" id="KOG0851">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012393_2_1_1"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140445">
        <property type="term" value="C:chromosome, telomeric repeat region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033260">
        <property type="term" value="P:nuclear DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
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        <property type="entry name" value="Euk_RPA1_DBD_C"/>
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        <property type="entry name" value="NA-bd_OB_tRNA"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
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    </dbReference>
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        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="Nucleic acid-binding proteins"/>
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    </dbReference>
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        <location>
            <begin position="6"/>
            <end position="107"/>
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        <location>
            <begin position="181"/>
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        </location>
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        <location>
            <begin position="290"/>
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        <location>
            <begin position="445"/>
            <end position="594"/>
        </location>
    </feature>
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        <location>
            <begin position="123"/>
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            <begin position="149"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC51392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="611" mass="68165" checksum="CDE641485DB2E7D0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHU8</accession>
    <name>W6ZHU8_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_55120</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="61" mass="6332" checksum="617D13C73EC5CD8B" modified="2014-04-16" version="1" fragment="single">AVTTTEVISATTYVCPEETTITYGPSTYTVPASGTLSIPQYTATYVHTPVVPAPAKSTPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHV1</accession>
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        <recommendedName>
            <fullName evidence="2">Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein</fullName>
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    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_84282</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_007685692.1"/>
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    <dbReference type="STRING" id="930090.W6ZHV1"/>
    <dbReference type="GeneID" id="19126435"/>
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    <dbReference type="eggNOG" id="KOG1906">
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    </dbReference>
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    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="2">
        <location>
            <begin position="179"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="562" mass="63730" checksum="BCEBF41EB147148B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHV9</accession>
    <name>W6ZHV9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_84205</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="P:mannosyl diphosphorylinositol ceramide metabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="entry name" value="Aureobasidin resistance protein Aur1"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE CATALYTIC SUBUNIT AUR1"/>
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    </dbReference>
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        <property type="entry name" value="PAP2_3"/>
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        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
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            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="397"/>
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        </location>
    </feature>
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            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC49575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="448" mass="50062" checksum="AD920AE2190C384A" modified="2014-04-16" version="1">MTNKSYLAFLENTTASDMLSRTTVPGLAALPSLIPHRVRRKWRATKSRIRSRQSPTSSIASLETSFSPSDTLRSLRTHSWSIYDAQYLFLAIVAIFSLSVSEAPGPFAKTFVATLLMTGLCLPITRQFLLPLLPTLTWLFLFSSCKYISEDYRPAIWVRVLPALENILYGSNLSNILSAHKHTVLDILAWLPYGVVHYVSPVIVSGCMFIWGPPGTLPIWARAFGYMNITAVLIQIVFPCSPPWYENTYGLAPANYSIHGDAAGLKAIDKLTGIDIYTSAFLGSPMVFGAFPSLHSGWATLETLFMGHVFPKLFPVYVFYTMWLWWSTMYFSHHYAVDLVAGSLLAGVCYFFGRANFLPHPQADKEFRWDYDFVEIGDPMDRAGYSMLDIYEEFPPNSDSDDWATGSSSSYSTGGRSPIGARSPTDDNQSLWDGDTVGSDTEHTLRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIF2</accession>
    <name>W6ZIF2_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_83482</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="EUC49780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="29207" checksum="1F23F3A82A2152ED" modified="2014-04-16" version="1">MPSWAITGASRGIGLEYVRQLSADVGNQVFALIRSQPSEDLSKLDSERKNLHVIKADVTDTQSLSEAATKVGKLTENKLDVFISNACHTGLDLRFYPTSAFLGKEKELKNEIDAPMSVNLIGAINSINRFLPLIRNGELKKIIYITSPTGDAEFTRKCGVTVTIGYTATKAAMNLVMSKYAAELKGEGIKTLALSPGWVDTDGTRDMAPTPEVLEMALQMFQKVNPDLTRLLSPEESVRMQLDVINNLTEEQSGLALSHHGNHNWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIU9</accession>
    <name>W6ZIU9_COCMI</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83195</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887104" evidence="1">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="55" mass="6436" checksum="9117C4B9C3ECFE85" modified="2014-04-16" version="1">MKTRNKRQKLLVHVPPSPPPSFLLLLLLLLLFWCVQQSDYSKTFMNRPPKENSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ06</accession>
    <name>W6ZJ06_COCMI</name>
    <protein>
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            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683591.1">
        <property type="nucleotide sequence ID" value="XM_007685401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ06"/>
    <dbReference type="GeneID" id="19126249"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83408"/>
    <dbReference type="HOGENOM" id="CLU_2654305_0_0_1"/>
    <dbReference type="OrthoDB" id="3693684at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887114" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="8378" checksum="15B846D53C6BD1CB" modified="2014-04-16" version="1">MHLPNLSAAVALLAIAVVTGPPLVGCMVGGRERDTVRLAVTCSVLHLHHGRGLFDPFVLFSERYSQHRLCKPRYPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ59</accession>
    <name>W6ZJ59_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Target of rapamycin complex subunit LST8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_82832</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683459.1">
        <property type="nucleotide sequence ID" value="XM_007685269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ59"/>
    <dbReference type="STRING" id="930090.W6ZJ59"/>
    <dbReference type="GeneID" id="19126137"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82832"/>
    <dbReference type="eggNOG" id="KOG0315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_5_1"/>
    <dbReference type="OrthoDB" id="400at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030950">
        <property type="term" value="P:establishment or maintenance of actin cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001558">
        <property type="term" value="P:regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000339">
        <property type="entry name" value="WD-repeat protein pop3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF0">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="71"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="112"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="203"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="267"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="328" mass="36045" checksum="F73DA25D9B518432" modified="2014-04-16" version="1">MSVILCTAGYDHTIRFWEALSGICSRTIPHPDSQVNRLCISPDKRYLAAAGHHTVKLYDIKSTNPNAILTFDGHTSNITGVAFHCESKWLVTSSEDGTVKIWDTRSGNVQRNYTHGVPVNDVVIHPNQGELISCDRGGNVRIWDLGENKCSHQLIPEDDVSVASVTVASDGSMVCAGNNAGNVYVWRMIQRSDTTSILPICKFIAHTTYITRVLLSPDVRHLATCSADHTARIWSVDTSAPHNVTPNDNLPSASERDPAAFPLETTLHGHQRWVWDCAFSADSAYLVTACSDHYARLWELGSQSIIRQYNGHHRGAVCVALNDTAVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJB0</accession>
    <name>W6ZJB0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tcp11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_22430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683396.1">
        <property type="nucleotide sequence ID" value="XM_007685206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJB0"/>
    <dbReference type="GeneID" id="19120248"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22430"/>
    <dbReference type="eggNOG" id="KOG1981">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005050_0_0_1"/>
    <dbReference type="OrthoDB" id="276323at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010737">
        <property type="term" value="P:protein kinase A signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF18">
        <property type="entry name" value="IQ CALMODULIN-BINDING MOTIF DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="449"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="982" mass="109647" checksum="38FBC5EB439DCE9C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJJ8</accession>
    <name>W6ZJJ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_99932</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
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        </source>
    </evidence>
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            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC43771.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="523" mass="56794" checksum="3F2F2C6D0B825752" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </location>
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        </location>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
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                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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            <end position="154"/>
        </location>
    </feature>
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        <source>
            <dbReference type="EMBL" id="EUC50785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="154" mass="15366" checksum="4003C82B955FF525" modified="2014-04-16" version="1">MFKLIVGSFLAMQMTALAAPQQQSGSSGVQITSLEKNATSTIGSGNVAAAGNLTPFGDIGVGCGINWKADTSYGGGLQAGSSDFGLGSGFTMTPGFINIGAGIGMNTVNASANIQFTGSKNGSVELVFESTSPVVCTPGTRDGKSIVTCKTINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLZ0</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="165" mass="18081" checksum="03538C3C93069155" modified="2014-04-16" version="1">MPAYVQSQSHQLSAAESVDPTTSPAASHALTATAARGDISLGPMVPPRPPPFALDNDQGAEIFQCNASSQLVTVCIKNARHTCLTTLLSCCYFHLSNSALGHDSYSSAIARAMVPPQPRQASSRTRRWLATSNRRRILAYAIMYYQPYLSGDICNKYTYIPHTYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM04</accession>
    <name>W6ZM04_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">DUF1254 domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="3" type="ORF">COCMIDRAFT_21406</name>
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    <organism evidence="3 4">
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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    </evidence>
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    <sequence length="155" mass="16839" checksum="4A5CA32EB738D53A" modified="2014-04-16" version="1">MVLPLVLVVLEAAVSVATEAAVATEAIVVVDGTTIDVAGATTEDPAVLTMNRSAAGIDTATVMVDMVEAETMAHESARTMATTTTTHEHDEGTKLDLRLSHVVQWFVKKVTSLFFAPAFLVNEGKIDSVQLLTFRLYSTAQYRRVRSTQHHEQHS</sequence>
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                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
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                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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            <strain evidence="2 3">ATCC 44560</strain>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963990">
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        </location>
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            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8213" evidence="2">
        <location>
            <begin position="25"/>
            <end position="150"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45116.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="150" mass="15009" checksum="4C031466CD87B60A" modified="2014-04-16" version="1">MYLLSVCLSALLAIQASAAPGLGKRQISCLRVGATATATWTNAAGRTCRWTGIVGSNFGTNSVNGGDYSCNGRCGAGCSGAALGNVYTLDCFSHDVCSWFNNASGGASDPNCGAAFNAAVDDTISGAVRGCGQTNPSNPAVRPSTSPICS</sequence>
</entry>
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    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC45331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="STRING" id="930090.W6ZP10"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_5435"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23297">
        <property type="entry name" value="ACP_SdgA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="20"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="996"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="2188"/>
            <end position="2265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="476"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="996"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1155"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="476"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="1028"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC45331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="2274" mass="249479" checksum="3E5EA9BCFCD2FE3F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPL7</accession>
    <name>W6ZPL7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_95276</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPL7"/>
    <dbReference type="GeneID" id="19128622"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95276"/>
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    <dbReference type="OrthoDB" id="10421478at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="58" mass="6662" checksum="3F61C09F87611D03" modified="2014-04-16" version="1" fragment="single">SFFQSYSELGCLVLRVVLHPLFLLGTNQCSHSNTCTVYVVFFFLFKIAQHLLCSSCWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ04</accession>
    <name>W6ZQ04_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane ATPase</fullName>
            <ecNumber evidence="10">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_94826</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="10"/>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687792.1">
        <property type="nucleotide sequence ID" value="XM_007689602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ04"/>
    <dbReference type="STRING" id="930090.W6ZQ04"/>
    <dbReference type="GeneID" id="19128522"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94826"/>
    <dbReference type="eggNOG" id="KOG0205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_6_0_1"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008553">
        <property type="term" value="F:P-type proton-exporting transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000005">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000008">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="386"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="747"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="774"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="805"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="839"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="876"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="916"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="78"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC45701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1002" mass="110399" checksum="E334D27B44D3EF99" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ30</accession>
    <name>W6ZQ30_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ30"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_22773"/>
    <dbReference type="eggNOG" id="ENOG502SX1G">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1142428_0_0_1"/>
    <dbReference type="OrthoDB" id="4821403at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890161" evidence="1">
        <location>
            <begin position="18"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="228" mass="25119" checksum="600A286D877532F7" modified="2014-04-16" version="1">MILSAVLTSAFALLASARYIPDGCPRKIGPDGVHARIPPFLNTTSQHYHSKPWCPPPVGFYFKPWWIVLATNPQYATMRNLQYDPTPVDPKDPTGLVNDLFSFQRPGNNTIFTTYGVDTPDPHLPAVLDFAATGILKGATSRFAILVWGCDSNRVPYYASYSTETNLTKTPPGIDLLSTNDKGPDQATIDAILKALKDLNTPEITEYVNKLNRTAQDGARKNLPRVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ67</accession>
    <name>W6ZQ67_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">P-type Cu(+) transporter</fullName>
            <ecNumber evidence="3">7.2.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Cu(2+)-ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_94551</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="17">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.8" evidence="3"/>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687699.1">
        <property type="nucleotide sequence ID" value="XM_007689509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ67"/>
    <dbReference type="STRING" id="930090.W6ZQ67"/>
    <dbReference type="GeneID" id="19128469"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94551"/>
    <dbReference type="eggNOG" id="KOG0207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_0_1_1"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="F:ATP hydrolysis activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:P-type divalent copper transporter activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140581">
        <property type="term" value="F:P-type monovalent copper transporter activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="4"/>
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    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
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        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
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    </dbReference>
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        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
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    </dbReference>
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        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
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        <property type="entry name" value="ATPase_P-typ_P_site"/>
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        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
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        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
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        <property type="entry name" value="ATPase_P-type_domA"/>
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        <property type="entry name" value="HAD-like_sf"/>
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        <property type="entry name" value="HAD_sf"/>
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    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
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    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
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        <property type="entry name" value="HMA_dom_sf"/>
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    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
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    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
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        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
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        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="ATP7, ISOFORM B"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF8">
        <property type="entry name" value="P-TYPE CU(+) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="HMA"/>
        <property type="match status" value="4"/>
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    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00942">
        <property type="entry name" value="CUATPASEI"/>
    </dbReference>
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        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
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    </dbReference>
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        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HAD-like"/>
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        <property type="entry name" value="HMA, heavy metal-associated domain"/>
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        <property type="entry name" value="ATPASE_E1_E2"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-0187">Copper transport</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="451"/>
            <end position="474"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="661"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="703"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1052"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1081"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="18">
        <location>
            <begin position="12"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="18">
        <location>
            <begin position="112"/>
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        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="18">
        <location>
            <begin position="201"/>
            <end position="267"/>
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    </feature>
    <feature type="domain" description="HMA" evidence="18">
        <location>
            <begin position="284"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00080126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC45821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1168" mass="124095" checksum="4D183901E572470A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZR09</accession>
    <name>W6ZR09_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">inositol-3-phosphate synthase</fullName>
            <ecNumber evidence="6">5.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_83140</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10716"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="5.5.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.4" evidence="6"/>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683564.1">
        <property type="nucleotide sequence ID" value="XM_007685374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZR09"/>
    <dbReference type="STRING" id="930090.W6ZR09"/>
    <dbReference type="GeneID" id="19126195"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83140"/>
    <dbReference type="eggNOG" id="KOG0693">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021486_2_0_1"/>
    <dbReference type="OrthoDB" id="2887at2759"/>
    <dbReference type="UniPathway" id="UPA00823">
        <property type="reaction ID" value="UER00787"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000069">
        <property type="entry name" value="Inositol-3-phosphate synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000204">
        <property type="entry name" value="Inositol-3-phosphate synthase 1-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11510">
        <property type="entry name" value="MYO-INOSITOL-1 PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07994">
        <property type="entry name" value="NAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0398">Inositol biosynthesis</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="14" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myo-inositol-1-phosphate synthase GAPDH-like" evidence="15">
        <location>
            <begin position="330"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC49934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="536" mass="58627" checksum="2EB6926CAE118A89" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6ZSC9</accession>
    <name>W6ZSC9_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">Ketopantoate reductase C-terminal domain-containing protein</fullName>
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        <name evidence="4" type="ORF">COCMIDRAFT_92553</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <dbReference type="EMBL" id="EUC46601.1"/>
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    </evidence>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
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            <end position="513"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="498"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46676.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
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        </location>
    </feature>
    <feature type="chain" id="PRO_5004887721" evidence="2">
        <location>
            <begin position="20"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="133"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51334.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="154" mass="16100" checksum="09AFCF8DC1462FF2" modified="2014-04-16" version="1" fragment="single">MVIFSKILLLAACSTCVVGGPVPRNHQRRQFTGYFNTSSIISSTSEKVVAQLDTALVVEPIQPTVFTSIAPGITFVNPDGEPLATQDPETVLSTSFITPTQKPTTEKSYSVIPTSTTTPGLKQAPVESSPTPTLSSDALSALSSSVKAAENSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVQ1</accession>
    <name>W6ZVQ1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_3165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685552.1">
        <property type="nucleotide sequence ID" value="XM_007687362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZVQ1"/>
    <dbReference type="GeneID" id="19121919"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3165"/>
    <dbReference type="HOGENOM" id="CLU_034958_0_0_1"/>
    <dbReference type="OrthoDB" id="3801515at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="426" mass="46491" checksum="4FB441B0DB8EA2B2" modified="2014-04-16" version="1">MTSSSRAIAVVDSVVLTSTDTDNISTPVTPADRFRTRPLRNDSAESSLDAAAASPNRAYAHPCPHHDSANYPNALPNTPPLKPAESRSRPVSPLGLANVRIRRSHHGSRLLQSPARAGHAARMRQLFEDASHEQQTLQPSHLPYPQLPNISAKASSPLARRGHVHSHSQQATTSPIRRLESLCIATTLLPGPPPGFAKTSQQSSQSWSDDSGYLIPGSRNKPNPKSIRASVLDDRISRWLTGVSTPNVHEPYAKLPQPNTYPKPQFCQRPSSNLSETASRSGQEALEASLADTVTIRDVFHIRTESTIRLATPPQLRPRAANNQVSFPDPDIQLSPLSPNVCIERGPSRYHSSRNLHNTASPTKSHYVSSKENAAPTNTPSHHAQRGSAQDSPCKIGIGTRFQHPSHTTHTSREIRTRRVDPQSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYK4</accession>
    <name>W6ZYK4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_23518</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684707.1">
        <property type="nucleotide sequence ID" value="XM_007686517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYK4"/>
    <dbReference type="GeneID" id="19120451"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23518"/>
    <dbReference type="eggNOG" id="ENOG502SWNK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075861_0_0_1"/>
    <dbReference type="OrthoDB" id="5400539at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020999">
        <property type="entry name" value="Chitin_synth_reg_RCR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12273">
        <property type="entry name" value="RCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="207" mass="23428" checksum="21CDD83A05683543" modified="2014-04-16" version="1">MALLKRYYCAETVDGDTECFVEDGFWYTERGIIIKWIVFALFFIIFFGWFVGGRIHAKQRLRKGLPLLSYHRFLISYSERQRHGQVPQNHFTFYQTQNPYATNNGANPQYTQRQDGAWAEPPPLYQNNDAPPQYFAPQGPAKTTPNQYAMEMGQYSGPPMAPGPQQSGVVGSAPATSDVEQGQASSQELPPRPAQAKIMGVLGRFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W7A059</accession>
    <name>W7A059_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH dehydrogenase [ubiquinone] iron-sulfur protein 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-15 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase 15 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_84709</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFS5 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684124.1">
        <property type="nucleotide sequence ID" value="XM_007685934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A059"/>
    <dbReference type="STRING" id="930090.W7A059"/>
    <dbReference type="GeneID" id="19126514"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84709"/>
    <dbReference type="eggNOG" id="ENOG502S71X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162182_0_1_1"/>
    <dbReference type="OrthoDB" id="9992197at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24141">
        <property type="entry name" value="NDUFS5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019342">
        <property type="entry name" value="NADH_UbQ_OxRdtase_FeS-su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="14"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR619342-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC49391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="112" mass="12457" checksum="48CFC42A5D53CBED" modified="2014-04-16" version="1">MASGYGLAGGPSRCFPFWQEVLACYTTNTTAEDNSGKAKCSPVLEDYYECLHHKKEAARTLALQAAYRKAEANITRDDAPSAGEIRRLGVLDAPLEEKNLKPSKWFPHRQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0F6</accession>
    <name>W7A0F6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_84394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684023.1">
        <property type="nucleotide sequence ID" value="XM_007685833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0F6"/>
    <dbReference type="STRING" id="930090.W7A0F6"/>
    <dbReference type="GeneID" id="19126460"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84394"/>
    <dbReference type="HOGENOM" id="CLU_099102_0_0_1"/>
    <dbReference type="OrthoDB" id="3692092at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="246" mass="27370" checksum="794E6816287ED8BE" modified="2014-04-16" version="1">MASLNELSCSRGLDNYPDPSCAVYPNAATNPSGVKVINHHSKNEAKPKNEVTPAFKRSMNFFCEADGTYRMPNVKPLWPDPLTWPPPTQQHPEKWSFSSTKCSTVWPDLSSSPPAPQGPIEPPTSKYRLRNQEKEEPYEKLGSAALLEGSIPYFGTGYREHGREIDTNAICRFFDKNRMRRRQSAKEDTPTIFSSVLPPSTRQVAAPSRQPDPPLGVCAYPAPPQPVTPSAPRYETYSHALASRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0G5</accession>
    <name>W7A0G5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_33152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683984.1">
        <property type="nucleotide sequence ID" value="XM_007685794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0G5"/>
    <dbReference type="GeneID" id="19122256"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33152"/>
    <dbReference type="HOGENOM" id="CLU_1447418_0_0_1"/>
    <dbReference type="OrthoDB" id="10296524at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="187" mass="20764" checksum="D6BBFA470B869204" modified="2014-04-16" version="1">MELRKLHMDIGRYPHMLSSMQVQHAITIFVGTYQWAGLNDRDSTPRGVLLQVPTGDVISLSRPLTTHADQQRVRLYQSQHHPPKTPGYPNWVVRNVPGCSKPGRADSAAPCLGWGLLTGRHGLLRCRCKAVKLLKSHKARDCASLSNNLWNPSIINHSCPTACASPSPRLHSSITSSSRLHFDPHID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2W3</accession>
    <name>W7A2W3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Golgi apparatus membrane protein TVP18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_1057</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Golgi membrane protein involved in vesicular trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TVP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683127.1">
        <property type="nucleotide sequence ID" value="XM_007684937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2W3"/>
    <dbReference type="STRING" id="930090.W7A2W3"/>
    <dbReference type="GeneID" id="19118735"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1057"/>
    <dbReference type="eggNOG" id="ENOG502S3AC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118698_0_0_1"/>
    <dbReference type="OrthoDB" id="5591789at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019365">
        <property type="entry name" value="TVP18/Ca-channel_flower"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13314">
        <property type="entry name" value="CALCIUM CHANNEL FLOWER HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13314:SF2">
        <property type="entry name" value="CALCIUM CHANNEL FLOWER HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10233">
        <property type="entry name" value="Cg6151-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01077">
        <property type="entry name" value="Cg6151-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16461" checksum="F1BE1188AD010E4D" modified="2014-04-16" version="1">MTLAEEFKSRNFSIYGQWTGVLCIFLCFALGIANIFHANFVIAFSIVCLVCSFIIIFIEIPLLLRICPTSSKFDEFIRKFSSNYMRAAIYGVMSTIQWISIWPMATSLIVAAIFLMLAAVFYALAGIKGQQFQGSKTLGGQGVAQMII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4Y8</accession>
    <name>W7A4Y8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper-fist domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_373</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682311.1">
        <property type="nucleotide sequence ID" value="XM_007684121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A4Y8"/>
    <dbReference type="GeneID" id="19123221"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_373"/>
    <dbReference type="eggNOG" id="ENOG502SQDA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021651_0_0_1"/>
    <dbReference type="OrthoDB" id="5600085at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:intracellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.430.10:FF:000001">
        <property type="entry name" value="Copper fist DNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.430.10">
        <property type="entry name" value="Copper fist DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051763">
        <property type="entry name" value="Copper_Homeo_Regul"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001083">
        <property type="entry name" value="Cu_fist_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036395">
        <property type="entry name" value="Cu_fist_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00649">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00617">
        <property type="entry name" value="COPPERFIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM01090">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00412">
        <property type="entry name" value="Cu_FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57879">
        <property type="entry name" value="Zinc domain conserved in yeast copper-regulated transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50073">
        <property type="entry name" value="COPPER_FIST_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Copper-fist" evidence="9">
        <location>
            <begin position="11"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="114"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="425"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC51161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="536" mass="56853" checksum="BDD6AC9E051B887A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YM26</accession>
    <name>W6YM26_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_109244</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964180">
        <property type="protein sequence ID" value="EUC40277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693213.1">
        <property type="nucleotide sequence ID" value="XM_007695023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YM26"/>
    <dbReference type="GeneID" id="19119393"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109244"/>
    <dbReference type="eggNOG" id="ENOG502S6CG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029871_3_2_1"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF1">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889024" description="Heme haloperoxidase family profile domain-containing protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="78"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC40277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="437" mass="46208" checksum="B9973138FC6B956C" modified="2014-04-16" version="1">MKTTSLLYSVSLFLGSALAFPANLLNADISSETLAEINSIVARIERETAAAASAKRQLGLGLVKPVFDANAQRVSVTGEHRYIAPGPNDIRGPCPGLNVLANHGYISRTGVASVIDLTTASTEVFGMATDLSAFLSVYSGLVAGDLTTVSIGGKPKSGGLLTGVTSSLGLLGEAQGLSASHNRFEADCSPTRGDLYKTGDTDSLNLAQFEELAAMPLGPNGYDLTVMHPFRGSRFNNSIATNGRYFAGPFTHYAINTATYLFTYHFFRNHSAQFPDGYLDLETLKSFEGVTGEKGSFKWAAGRERIPDNYYRRAIGDEYGIASFALDAVGALQALPYMAVVGGNTGKPNTFTGVNIADLTGGVFNAQTLLEGNNAMCFAFQFVQFASPDILDGLLGNVLLAVRKLTAVLDPILAILGCPQAAKFDMGLLSSFPGGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMN7</accession>
    <name>W6YMN7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">asparaginase</fullName>
            <ecNumber evidence="1">3.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_108523</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the asparaginase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="KI964156">
        <property type="protein sequence ID" value="EUC40552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692937.1">
        <property type="nucleotide sequence ID" value="XM_007694747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMN7"/>
    <dbReference type="STRING" id="930090.W6YMN7"/>
    <dbReference type="GeneID" id="19119264"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108523"/>
    <dbReference type="eggNOG" id="KOG0503">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019134_3_1_1"/>
    <dbReference type="OrthoDB" id="542841at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009066">
        <property type="term" value="P:aspartate family amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08963">
        <property type="entry name" value="L-asparaginase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1170:FF:000003">
        <property type="entry name" value="60 kDa lysophospholipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.40:FF:000001">
        <property type="entry name" value="L-asparaginase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000284">
        <property type="entry name" value="Lysophospholipase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="entry name" value="L-asparaginase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041725">
        <property type="entry name" value="L-asparaginase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707:SF28">
        <property type="entry name" value="60 KDA LYSOPHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500176">
        <property type="entry name" value="L_ASNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00057">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="L-asparaginase N-terminal" evidence="7">
        <location>
            <begin position="14"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase/glutaminase C-terminal" evidence="8">
        <location>
            <begin position="253"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="436"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="469"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="523" mass="56344" checksum="2483DB0468D7316F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMX2</accession>
    <name>W6YMX2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_30457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964149">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMX2"/>
    <dbReference type="GeneID" id="19121682"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30457"/>
    <dbReference type="HOGENOM" id="CLU_1916711_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="132" mass="14346" checksum="72B5DBC51B6160AD" modified="2014-04-16" version="1">MEYSETIQPHFLGRTSPAPTRQALVRSWRWQIHAGTTEAAIGGMAARPESSGCICIKRSNHVPCDAVIMDEKTFRERCMTPKVPEQVDTGVKEAVGSKSGAPVSNKNGPHKLPTEATAPRVPTISKASLFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNR5</accession>
    <name>W6YNR5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964124">
        <property type="protein sequence ID" value="EUC41027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692453.1">
        <property type="nucleotide sequence ID" value="XM_007694263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNR5"/>
    <dbReference type="GeneID" id="19127997"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9206"/>
    <dbReference type="eggNOG" id="ENOG502S91F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053362_0_0_1"/>
    <dbReference type="OrthoDB" id="5421421at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="43805" checksum="17932A2061E10CC7" modified="2014-04-16" version="1">MSPQSLQPSMSHLPESPLPSHEAIHVPASAWYGPSISAPECSSEPSYASYNNYITPHTSSINLSPPATAFPYMPKHPGSATQLDPSVTLSPGTVYSRDSVVPEPASPLEEPQSDPKYSLHQSTLRLGPQSHLLDRNHSGLSNLNTARANVSWAMNPLGIHSSHESYYPAFPSLNHSPRLSEPSVELSNQMVSPQPRRMYTPIAPLPQETPRSHSTKRYHEDEEEALDSSKRRKRSDSQTSTQFELSEEDKLLLKLKEQDSMPWKDIAARFQTELQKSYQIPALQMRYKRLRERMRVWTDTDRKALRMAHEYWLQNKFEIIAQKMLEFGAQEKWTARQCSRQWQMMDHPPLSYAQFDHHLQQGFAPYAMSPIEPPPNNSLPFLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPB2</accession>
    <name>W6YPB2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_40598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964115">
        <property type="protein sequence ID" value="EUC41197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692284.1">
        <property type="nucleotide sequence ID" value="XM_007694094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPB2"/>
    <dbReference type="STRING" id="930090.W6YPB2"/>
    <dbReference type="GeneID" id="19123906"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40598"/>
    <dbReference type="eggNOG" id="ENOG502SJ0E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115019_0_0_1"/>
    <dbReference type="OrthoDB" id="3454835at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="23"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="145" mass="16963" checksum="AEC2CF3CFAF524DB" modified="2014-04-16" version="1">MSELPSEPQQSRYLCLTICGYRKPGMSEEDYRNHMVNVSAPLTKDLMVKYGIRRWTQIHNQSATRALMSQLFDPQMVHLADFDCFSQVVFKSVDDYVRMKQDPWYKEHLVGDHEKFADTKKSMMTIGWIEEFIDDGKVVEANKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPL2</accession>
    <name>W6YPL2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="7">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_106521</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Vacuole membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="7"/>
    <dbReference type="EMBL" id="KI964110">
        <property type="protein sequence ID" value="EUC41297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692196.1">
        <property type="nucleotide sequence ID" value="XM_007694006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPL2"/>
    <dbReference type="STRING" id="930090.W6YPL2"/>
    <dbReference type="GeneID" id="19118878"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106521"/>
    <dbReference type="eggNOG" id="KOG2381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009049_2_0_1"/>
    <dbReference type="OrthoDB" id="3349449at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039756">
        <property type="entry name" value="Lsb6/PI4K2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="165"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="409"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="656"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="409"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="665"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC41297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="762" mass="87284" checksum="654BEC5043A9F5BF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQX6</accession>
    <name>W6YQX6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAD-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_41568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964205">
        <property type="protein sequence ID" value="EUC40040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693442.1">
        <property type="nucleotide sequence ID" value="XM_007695252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQX6"/>
    <dbReference type="STRING" id="930090.W6YQX6"/>
    <dbReference type="GeneID" id="19124082"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41568"/>
    <dbReference type="eggNOG" id="KOG2914">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_14_1_1"/>
    <dbReference type="OrthoDB" id="2107174at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044999">
        <property type="entry name" value="CbbY-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42896:SF2">
        <property type="entry name" value="CBBY-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42896">
        <property type="entry name" value="XYLULOSE-1,5-BISPHOSPHATE (XUBP) PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="27600" checksum="0535A3286C9C2626" modified="2014-04-16" version="1">MGKAKYIMLDCDNTLVQSERYAFEACADLTNEVLSKHNIDARYTAETLLEDFVGHNFRGMLNGLQKKHNFQMPPEEMDDYVQQELGAVTRKLSQKAVECPGVTEQLKWLKEQGYPMAVVSTSAKSRVVASIEKAGIDHFFPNEHVYSAATSLNPPSSKPDPKIYLYAAEQLGVKPSEAVTVEDSKSGATAAMRAGIPCIGYVGIYGIEEGKEKMEEMAKLLTEETKCAAIMYDWKDFPEHLKKVEASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR02</accession>
    <name>W6YR02_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964220">
        <property type="protein sequence ID" value="EUC39933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693541.1">
        <property type="nucleotide sequence ID" value="XM_007695351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR02"/>
    <dbReference type="STRING" id="930090.W6YR02"/>
    <dbReference type="GeneID" id="19119546"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110112"/>
    <dbReference type="eggNOG" id="KOG4614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047290_1_0_1"/>
    <dbReference type="OrthoDB" id="17089at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007849">
        <property type="entry name" value="ATP10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28106">
        <property type="entry name" value="MITOCHONDRIAL ATPASE COMPLEX SUBUNIT ATP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28106:SF1">
        <property type="entry name" value="MITOCHONDRIAL ATPASE COMPLEX SUBUNIT ATP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05176">
        <property type="entry name" value="ATP-synt_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="316" mass="35744" checksum="044819C6CCAAC8B9" modified="2014-04-16" version="1">MLQLRISAPRRRILPSRPSICSRCQTRIVTAAIAQQSFARTFTSAHSLRRPATDPKAPESAPTPDPKDEDIFVPKPLGRPIGFKSPPQPGENASTPKTKKDYSGMTMSQRNLEKRKDLVEKWGTNYFRDFKNIRKYRSGKTFMANPRIFKKEAALYFPNFHGDTLEGKDRDTTNVLAGKVSVVNVYSSQWGLNQVETFTGAKTNTNLHNMLAQHPGIAQMVDVNIEENTMKAWIIALFQWRLKASKPKEDWGKYFVVRKGVSERIRETIGLLNGRVGYIYLVDQDCKIRWAGSGNAEGTEMEDMNKGFAKLIAEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR35</accession>
    <name>W6YR35_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">Lanthionine synthetase C-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_104939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964081">
        <property type="protein sequence ID" value="EUC41912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693402.1"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031179">
        <property type="term" value="P:peptide modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04794">
        <property type="entry name" value="euk_LANCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12736">
        <property type="entry name" value="LANC-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12736:SF7">
        <property type="entry name" value="LANC-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF158745">
        <property type="entry name" value="LanC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR607822-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="43073" checksum="BC9EB7C4E6FCA353" modified="2014-04-16" version="1">MSEEGAPSAATAEKAAPPSIPRYFRNDAPLARRDPHKQLLASLDRLITDYPPHHIPPGGGLYYGPISVAFLFYALHDLYPDLKLDGYPLNTWSAAYIEQAQTHIKEFPPPSPKKCGVSNDIMSLLALYAITAKDPDTVKELCDHAAVMLEDGTSNEWLYGRAGYLYLLRLVRKAFTDNKEITELIEDTADEIIENIMDSPRPWKWHGKAYVGAVHGAIGIITQIVLTDPAWAPKLDAELGALLSYQYESGNFPSSLPPGRDRLVQVCHGAPGVVISLLSIRKYFPGLRDRIDRVVAKARECIWERGLLTKEPCLCHGITGNALALEGKQFEHFMTYTTGHEIKSMAKDAMLEKSDDPSALWCGEAGRAWAWAVADKDLDKRLLGYNDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS53</accession>
    <name>W6YS53_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate-binding module family 21 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_109076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964174">
        <property type="protein sequence ID" value="EUC40338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693151.1">
        <property type="nucleotide sequence ID" value="XM_007694961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS53"/>
    <dbReference type="STRING" id="930090.W6YS53"/>
    <dbReference type="GeneID" id="19119363"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109076"/>
    <dbReference type="eggNOG" id="KOG3986">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012287_0_0_1"/>
    <dbReference type="OrthoDB" id="1881at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000164">
        <property type="term" value="C:protein phosphatase type 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001069">
        <property type="term" value="F:glycogen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005979">
        <property type="term" value="P:regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="entry name" value="Carbohydrate binding type-21 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005036">
        <property type="entry name" value="CBM21_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050782">
        <property type="entry name" value="PP1_regulatory_subunit_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307:SF36">
        <property type="entry name" value="GLYCOGEN-BINDING SUBUNIT 76A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03370">
        <property type="entry name" value="CBM_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51159">
        <property type="entry name" value="CBM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM21" evidence="2">
        <location>
            <begin position="305"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="623"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="701" mass="76817" checksum="00F22956774FECBB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSZ7</accession>
    <name>W6YSZ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MIF4G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_108147</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964146">
        <property type="protein sequence ID" value="EUC40690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692802.1">
        <property type="nucleotide sequence ID" value="XM_007694612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSZ7"/>
    <dbReference type="STRING" id="930090.W6YSZ7"/>
    <dbReference type="GeneID" id="19119190"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108147"/>
    <dbReference type="eggNOG" id="KOG1104">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013816_0_0_1"/>
    <dbReference type="OrthoDB" id="10252707at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000079">
        <property type="entry name" value="Related to cap binding protein 80 (Cbp80)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000035">
        <property type="entry name" value="snRNA cap binding complex subunit (Gcr3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000045">
        <property type="entry name" value="snRNA cap binding complex subunit (Gcr3), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027159">
        <property type="entry name" value="CBP80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015172">
        <property type="entry name" value="MIF4G-like_typ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015174">
        <property type="entry name" value="MIF4G-like_typ-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412">
        <property type="entry name" value="CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412:SF2">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09088">
        <property type="entry name" value="MIF4G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09090">
        <property type="entry name" value="MIF4G_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G-like type 1" evidence="2">
        <location>
            <begin position="356"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G-like type 2" evidence="3">
        <location>
            <begin position="564"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="832"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="862" mass="97972" checksum="869171B7AD21E1A8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTU3</accession>
    <name>W6YTU3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RTA1 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_30209</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964129">
        <property type="protein sequence ID" value="EUC40953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692540.1">
        <property type="nucleotide sequence ID" value="XM_007694350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTU3"/>
    <dbReference type="GeneID" id="19121638"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30209"/>
    <dbReference type="eggNOG" id="ENOG502RDNH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_0_1_1"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF34">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="39076" checksum="901E25555D18F1CE" modified="2014-04-16" version="1">MSNGEIVPGSVYLYDPVNWAPPMFTAWFAVATIVHVWQCIKYKAWKVAGLHPVCGLLFTAGFALRSYGAIHYKDVNIYIASTILIYCAPPILELANYHVLGRILYYVPYYSPLHPGRTLTTFGFVSSIVEVLNAIGVAWLANPNAPESYIKRGDVLLKASLVLQVGVITAFCIIAGIFHARCIRGGITTRKVRGPLVTLYLSMTLILLRTVYRIVEHFGTTAIYEHSPPDWDPETIPSVLRYEWFFWVFEASPMLVNSILWNYRHPRHYLPEDYHVYVAQNGRTELQGPGWKDDMPWWMTFIDPCGLTASLTGSKRKEKPFWESNGYQAVDLEEGRSNDASQSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU63</accession>
    <name>W6YU63_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_78849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964043">
        <property type="protein sequence ID" value="EUC42997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690523.1">
        <property type="nucleotide sequence ID" value="XM_007692333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU63"/>
    <dbReference type="STRING" id="930090.W6YU63"/>
    <dbReference type="GeneID" id="19125422"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_78849"/>
    <dbReference type="eggNOG" id="ENOG502S5WK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098391_1_0_1"/>
    <dbReference type="OrthoDB" id="19690at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="145" mass="16735" checksum="F04D72D427BA928A" modified="2014-04-16" version="1" fragment="single">RTFSLFPSSRPPTNRIFDPIRQPNDLHTLTLLNAADNRALVTFWTASWCQTCQAIKPLLRKLIEEEKVGEREGGLGFVEVMMDSVLIEDLPVRYRISSMPTLLAFSRQEAQFDTRLTRPEEMRNKEFLREWLVKEALRGGRRGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU68</accession>
    <name>W6YU68_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar-sorting protein SNF7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Vacuolar protein-sorting-associated protein 32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_101926</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF7 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964042">
        <property type="protein sequence ID" value="EUC43002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690467.1">
        <property type="nucleotide sequence ID" value="XM_007692277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU68"/>
    <dbReference type="STRING" id="930090.W6YU68"/>
    <dbReference type="GeneID" id="19117973"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101926"/>
    <dbReference type="eggNOG" id="KOG1656">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071097_1_0_1"/>
    <dbReference type="OrthoDB" id="5592979at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904669">
        <property type="term" value="P:ATP export"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070676">
        <property type="term" value="P:intralumenal vesicle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF10">
        <property type="entry name" value="GH13992P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="174"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="23"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="225" mass="25137" checksum="E9ABC1EB46035DC2" modified="2014-04-16" version="1">MSGWGLGWFGGGQAKKEAPKKAILQLRGQLEMLNKREKHLQNQMDEQDALARKYVSTNKQAAKSALRRKKQFEHSLEQTSSQIMTLEQQIYSIESANINKETLDAMKNAGAAMKQIHAGLTIDKVDDVMEGLREQHAIGEEISEAITSSVANNGIDEDELDEELAELQQEKLDEQMLNTGSVPIHDAPSSQKLPQAPSTNPKAPQRVEEDDEEEELRKLQAEMAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVE3</accession>
    <name>W6YVE3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_8793</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964099">
        <property type="protein sequence ID" value="EUC41520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691962.1">
        <property type="nucleotide sequence ID" value="XM_007693772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVE3"/>
    <dbReference type="STRING" id="930090.W6YVE3"/>
    <dbReference type="GeneID" id="19127161"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8793"/>
    <dbReference type="eggNOG" id="KOG0897">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003143_1_0_1"/>
    <dbReference type="OrthoDB" id="109543at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23802">
        <property type="entry name" value="UBCc_UBE2Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000107">
        <property type="entry name" value="Ubiquitin conjugating enzyme, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051838">
        <property type="entry name" value="ARTD_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21328">
        <property type="entry name" value="POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="1032"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="104"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="956"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="294"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1220" mass="135645" checksum="EEAC3C5735F3AB98" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW14</accession>
    <name>W6YW14_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dipeptidyl-peptidase IV</fullName>
            <ecNumber evidence="4">3.4.14.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Dipeptidyl peptidase IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_8608</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. Contributes to pathogenicity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.</text>
            <dbReference type="EC" id="3.4.14.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S9B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.5" evidence="4"/>
    <dbReference type="EMBL" id="KI964089">
        <property type="protein sequence ID" value="EUC41728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691747.1">
        <property type="nucleotide sequence ID" value="XM_007693557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW14"/>
    <dbReference type="STRING" id="930090.W6YW14"/>
    <dbReference type="GeneID" id="19126794"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8608"/>
    <dbReference type="eggNOG" id="KOG2100">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006105_0_2_1"/>
    <dbReference type="OrthoDB" id="16520at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000003">
        <property type="entry name" value="Dipeptidyl peptidase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.140.10.30">
        <property type="entry name" value="Dipeptidylpeptidase IV, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050278">
        <property type="entry name" value="Serine_Prot_S9B/DPPIV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731:SF162">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731">
        <property type="entry name" value="PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
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            <begin position="1"/>
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            <begin position="17"/>
            <end position="783"/>
        </location>
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        <location>
            <begin position="102"/>
            <end position="468"/>
        </location>
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            <begin position="554"/>
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        </location>
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        </location>
    </feature>
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        </location>
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        </location>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
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        </source>
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    </evidence>
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            <dbReference type="Pfam" id="PF00326"/>
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            <dbReference type="Pfam" id="PF00930"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="783" mass="87637" checksum="ADB59C70B973B408" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWY7</accession>
    <name>W6YWY7_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">COCMIDRAFT_38172</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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            <end position="217"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="449" mass="50145" checksum="AE5E853B764BAEB3" modified="2014-04-16" version="1">MNRQTNIIDDDEVARAMAAASQAKGNNVPAASKVTGGGAVAPIRPNKTTTVPAARKATRTPVTATLSQHLRGQFYEANGLKIPLNDQDGLGDKKRQHARLAEALLRKDLEELLDIVEQYAGTEKRIEFCMLELSKVEVATWIEEKETLALGRHPKSTLPLPAKNTFDPSRTPAAPTLSNGTTTLSVPSTKENLSHTAVRNDTHEQSDSRKRRIHEDELNSQPPQKLQKLDTPAEPAAGADENQADAVQQVNSSPVIVSSLPQISKKIETHKVARDREVQHIQFMSDTGMDASNLDLSTTIFHGKNIDRVLTATTNPRTGAIQFFDTTVHRNKSIPPMLHAPFLKHGNHGRHGDFVHDPDRTTGLGHQIASHDHHKWNEFIVFNGMWRHRKPHSVSGREAMLAEREIRETWEKWQIWYGEFVEKYPGYAVAHLWPCGCEKVIEGYDSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXB7</accession>
    <name>W6YXB7_COCMI</name>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="eggNOG" id="ENOG502RZ1G">
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    <dbReference type="OrthoDB" id="5245063at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048379">
        <property type="entry name" value="Rad26-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022093">
        <property type="entry name" value="Rad26-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048380">
        <property type="entry name" value="Rad26-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21046">
        <property type="entry name" value="Rad26-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12331">
        <property type="entry name" value="Rad26-like_helical_rpts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21048">
        <property type="entry name" value="Rad26-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad26-like N-terminal" evidence="5">
        <location>
            <begin position="331"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Rad26-like helical repeats" evidence="3">
        <location>
            <begin position="436"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Rad26-like C-terminal" evidence="4">
        <location>
            <begin position="671"/>
            <end position="734"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
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        <location>
            <begin position="218"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
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        </location>
    </feature>
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        </location>
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        <location>
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        </location>
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            <end position="93"/>
        </location>
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        <location>
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            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21048"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="740" mass="81673" checksum="8BAC1AA85DE32665" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXE0</accession>
    <name>W6YXE0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_27547</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat NOL10/ENP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964012">
        <property type="protein sequence ID" value="EUC44082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689398.1">
        <property type="nucleotide sequence ID" value="XM_007691208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXE0"/>
    <dbReference type="STRING" id="930090.W6YXE0"/>
    <dbReference type="GeneID" id="19121137"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27547"/>
    <dbReference type="eggNOG" id="KOG2321">
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        </location>
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        </location>
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        </location>
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        <source>
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            <dbReference type="Pfam" id="PF23098"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44082.1"/>
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        <source>
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        </source>
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    <sequence length="736" mass="81970" checksum="82BB3E882DCFAD67" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="23414" checksum="15493E5D06C9F1F6" modified="2014-04-16" version="1">MGKTRQRVKQACNRCRYKKTKVSARVCNKCRADDAVCSYIQDEDHQRDKTSPVALLEAQIRQLQVTVQTLYEYIRTGHNLPMLPGRSPGNDRPLLHDIVAHVNTLSTYMERSSEELQHEVPWLSAASTMSLPQSQPETSSFLTFAATEPQLDTFVASSMQLDPMLTEYNLAQTDYESLESRFDLQEFWSFADANPAHAASLRRWL</sequence>
</entry>
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        <name evidence="1" type="ORF">COCMIDRAFT_103350</name>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC42510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="61" mass="6162" checksum="2CA12671775D52CC" modified="2014-04-16" version="1">MTIQVAGAAAVRRRRLIDIYGCRTIKSTLLAGWLSCPAAQGGGGCMGRVCGGSGALGARKP</sequence>
</entry>
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    <accession>W6Z007</accession>
    <name>W6Z007_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Copper radical oxidase</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_38843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692107.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z007"/>
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    <dbReference type="eggNOG" id="ENOG502SCD5">
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    </dbReference>
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    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF56">
        <property type="entry name" value="GALACTOSE OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Apple" evidence="2">
        <location>
            <begin position="123"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="697" mass="76204" checksum="915D68D6ADD8DFAA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z086</accession>
    <name>W6Z086_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_101227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964034">
        <property type="protein sequence ID" value="EUC43290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690207.1">
        <property type="nucleotide sequence ID" value="XM_007692017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z086"/>
    <dbReference type="GeneID" id="19117832"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101227"/>
    <dbReference type="HOGENOM" id="CLU_3055842_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="54" mass="5949" checksum="D06F581BD7F9A5E1" modified="2014-04-16" version="1" fragment="single">SLIALRLGTQVHRLAHTCLDSTHLDKPPYSFGPLSRPGWRHQVSLGSFTPPVCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0T4</accession>
    <name>W6Z0T4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EXPERA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_95749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963986">
        <property type="protein sequence ID" value="EUC45362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688163.1">
        <property type="nucleotide sequence ID" value="XM_007689973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0T4"/>
    <dbReference type="STRING" id="930090.W6Z0T4"/>
    <dbReference type="GeneID" id="19128718"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95749"/>
    <dbReference type="eggNOG" id="ENOG502S97T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076143_0_0_1"/>
    <dbReference type="OrthoDB" id="60858at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919">
        <property type="entry name" value="PROTEIN CBG05606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="30346" checksum="AA9CBCA69C3FB697" modified="2014-04-16" version="1">MVTTRSRPQGDFPASEPSPTKKTPRSRNSTASPAPPDFSASPSGAASLAKRAVSNAFDEISPPAPAAIGETAWCHTASKVTLVWLSISWPLVLWDTLYILLRPHTMAGGAIQWPLWTPYETYAAIDYVYGWPGWENHDGFGSAQGVLNAIELILYGLYALTVYNHGQPAAGGTGVEVSKDKGGFFAGGIKVRGKSGNRAVLIGFTAAVMTLSKTILYYCNEYFSDFANIRHNDWFTLISLYIVMNGLWIVFPAYMVTVFGTDIITALDYASDPSSKKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1M0</accession>
    <name>W6Z1M0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_36651</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP12 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687819.1">
        <property type="nucleotide sequence ID" value="XM_007689629.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z1M0"/>
    <dbReference type="GeneID" id="19123079"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36651"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1737">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3015">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001040_0_1_1"/>
    <dbReference type="OrthoDB" id="1854502at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030011">
        <property type="term" value="P:maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043461">
        <property type="term" value="P:proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13292">
        <property type="entry name" value="PH_Osh1p_Osh2p_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000281">
        <property type="entry name" value="Oxysterol binding protein (Osh1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.120:FF:000008">
        <property type="entry name" value="Oxysterol binding protein (Osh1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000061">
        <property type="entry name" value="Oxysterol binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3580.10">
        <property type="entry name" value="ATP12 ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2180.10">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011419">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042272">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023335">
        <property type="entry name" value="ATP12_ortho_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF205">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP12"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="555"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="662"/>
            <end position="694"/>
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    </feature>
    <feature type="domain" description="PH" evidence="14">
        <location>
            <begin position="750"/>
            <end position="845"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="35"/>
            <end position="89"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="372"/>
            <end position="465"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="491"/>
            <end position="510"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="870"/>
            <end position="906"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="911"/>
            <end position="930"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="946"/>
            <end position="970"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1069"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1178"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="70"/>
            <end position="82"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="372"/>
            <end position="383"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="401"/>
            <end position="412"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="444"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="493"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="878"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="893"/>
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="949"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
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            <begin position="1069"/>
            <end position="1101"/>
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        <location>
            <begin position="1109"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008231"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC45652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1621" mass="179589" checksum="BABF53D3AB9CFCE0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2A0</accession>
    <name>W6Z2A0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_94440</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="11"/>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687647.1">
        <property type="nucleotide sequence ID" value="XM_007689457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2A0"/>
    <dbReference type="STRING" id="930090.W6Z2A0"/>
    <dbReference type="GeneID" id="19128447"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94440"/>
    <dbReference type="eggNOG" id="KOG1389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_1_1_1"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF8">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="15">
        <location>
            <begin position="44"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="16">
        <location>
            <begin position="307"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="13">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC45877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="429" mass="44749" checksum="5FFA9B7745D1D97B" modified="2014-04-16" version="1">MANQAPNKVQERLTQVEGHLLGGSASSGASKGRKNLLEKRPDDVVVTCALRTAFTKGGKGGFKDTQAADLLHGAYKAIIERSGIDPKLVEDIAVGAVLAPGGGATEFRAAALAAGFPTTTAVKSLNRQCSSGLQACVDIANAIKSGMIEVGIGAGAESMSTQYGPGAVTEFSELLENHKEAANCKVPMGVLSEQMAKAKGIARADQDAFAASSFQKAVEAQKQGLFDEEIAPLTVKWTNPKTDKEETITVSKDDGVRQGITPESLSKIRPAFSKDGSIHAGNASQISDGAAAVLLMKRSTAERLGQKIIGKFVQASIVGVPPLLMGVGPAAAIPVVLEKTGLNKNEVDIYEINEAFASQCLYCINELSLDMKKINPKGGAIAFGHPLGVTGARQVSTLLTELRRTKQQIGVTSMCIGTGMGMAAVWVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2W1</accession>
    <name>W6Z2W1_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_104665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964077">
        <property type="protein sequence ID" value="EUC41999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2W1"/>
    <dbReference type="GeneID" id="19118554"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104665"/>
    <dbReference type="eggNOG" id="ENOG502RJYJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040818_0_0_1"/>
    <dbReference type="OrthoDB" id="5326588at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="442"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
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        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="460"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="514" mass="56681" checksum="BE122AC72FE0DE88" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3R8</accession>
    <name>W6Z3R8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC46392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3R8"/>
    <dbReference type="GeneID" id="19122920"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36009"/>
    <dbReference type="HOGENOM" id="CLU_2016635_0_0_1"/>
    <dbReference type="OrthoDB" id="3786647at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="116" mass="12773" checksum="B936B95CE2141463" modified="2014-04-16" version="1">MPIFRTLTTKLKTSLSASSSPDTTPVQSPISPQASSPLSSFERLSGRKQASASTTAVDATAGERPQVQERTDSFMTHHGTQGSKESVVERKMVTMTMTMTKRTSRFREELDFEAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4F4</accession>
    <name>W6Z4F4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_103365</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964059">
        <property type="protein sequence ID" value="EUC42499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4F4"/>
    <dbReference type="STRING" id="930090.W6Z4F4"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_103365"/>
    <dbReference type="eggNOG" id="KOG1646">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046346_0_0_1"/>
    <dbReference type="OrthoDB" id="10260596at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_eS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014401">
        <property type="entry name" value="Ribosomal_eS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_eS6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002129">
        <property type="entry name" value="Ribosom_S6_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="239" mass="27539" checksum="55777F290C8C5730" modified="2014-04-16" version="1">MKLNISYPNNGTQKLIEIDDERKLRVFMERRMGHEVPGDSVGDEFKGYIFRITGGNDKQGFPMKQGVMHPTRVRLLLSDGHSCYRPRRTGERKRKSVRGCIVGMDLSVLALSIVKKGDEDIPGLTDIVHPKRLGPKRATKIRRFFGLSKEDDVRKFVIRREVQPKKEGARPYTKAPKIQRLVTPQRLQHKRHRLALKRRRAEASKDAANEYAQILSKRINDAKAAHDEARKRRASSMKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4F8</accession>
    <name>W6Z4F8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_97740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4F8"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_97740"/>
    <dbReference type="HOGENOM" id="CLU_3129636_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="50" mass="5880" checksum="B4ADDB0221D208B3" modified="2014-04-16" version="1" fragment="single">NHINNRYTSSISAAARVYTPISHYRAKNLTDSSHRNHKIYSPFLRVHDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4K1</accession>
    <name>W6Z4K1_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_97085</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4K1"/>
    <dbReference type="STRING" id="930090.W6Z4K1"/>
    <dbReference type="GeneID" id="19128984"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97085"/>
    <dbReference type="eggNOG" id="ENOG502SZDW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1723464_0_0_1"/>
    <dbReference type="OrthoDB" id="4338954at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="99"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="178" mass="19691" checksum="AA6FBF689434EB33" modified="2014-04-16" version="1">MSFLLRTSTLVRQRLFTTSARARTAISLEDATAAHMAAASGASVVPKLGRVARWYLPTMAMVAIGMIYLPRDASSSQPRRPLSLGDANANIGFGVTNALNDANRKVHSALELTQEQKNQMLMDAYGERSSLQDMERAIAGLEARLTTRKDRNKILEEAYGEKTSIEDLQRAMEIYEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4U1</accession>
    <name>W6Z4U1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_96790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC44995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688497.1">
        <property type="nucleotide sequence ID" value="XM_007690307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4U1"/>
    <dbReference type="GeneID" id="19128918"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96790"/>
    <dbReference type="eggNOG" id="ENOG502SU96">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116849_1_1_1"/>
    <dbReference type="OrthoDB" id="5309803at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="119" mass="13215" checksum="6CC57733B80E7986" modified="2014-04-16" version="1">MGLFSILPESFAVVETWITRIFLFLGLIAIAPWAVLLVYDILLYVFRAGAHEIPVVGGRARGKSRPRAPSLTERPSGRRRKFSLRGFEKPVVNTGGTNADSHDARSRRITEETTEDSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z509</accession>
    <name>W6Z509_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_97111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963996">
        <property type="protein sequence ID" value="EUC44843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688649.1">
        <property type="nucleotide sequence ID" value="XM_007690459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z509"/>
    <dbReference type="GeneID" id="19128989"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97111"/>
    <dbReference type="eggNOG" id="ENOG502RI70">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1094763_0_0_1"/>
    <dbReference type="OrthoDB" id="3777003at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="266" mass="29823" checksum="C4286B9C2C4EF7D2" modified="2014-04-16" version="1">MIFGGLEIVAGGYLIHRHYRKKNQANTAENDAQQKRHHTFPGAICSKQQQQQQQHYYQQHTIQHPSQPPQHHQPALPNQKYACYAIAPQPRPQLYTPQTLPPQDFQHHQHAPPLPAHQRPQLPPQPHSFTIPRRPVPERKPQIIIQPSLQRTDSFATLSRMPIANGYRPHDVREEEPIQPASAGGHGGHGVGGGVYSNAGYSMSTPAFGATATSPGLTYEMATAEDVEGWERYGYRREGEHDRPHYAPTVSTELGERDVAPPPYVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z576</accession>
    <name>W6Z576_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nicotinamide-nucleotide adenylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_91436</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686587.1">
        <property type="nucleotide sequence ID" value="XM_007688397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z576"/>
    <dbReference type="STRING" id="930090.W6Z576"/>
    <dbReference type="GeneID" id="19127883"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91436"/>
    <dbReference type="eggNOG" id="ENOG502S55N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032651_0_0_1"/>
    <dbReference type="OrthoDB" id="5591297at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31285">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31285:SF0">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="34071" checksum="D05B3D4B7AC9EB99" modified="2014-04-16" version="1">MADMASRIASLRSLLPDLESALHSFTSSPAKFRVVRTVNDTPTQPQTLYILDSSFNPPSLAHFTLASSALKNSAPLEQSPYRLLLLFSTHNADKAPSPASFVQRIALMTAFAEDLSQSLKKGTYSSNVDIANLSIDIGLTKEPYYSDKSAAIAQATPPFYASNPRHIHLVGYDTLIRFCNPKYYPKHDPPLSALEPFFAAGHKLRVTQRPTDANDESSREFGSTQEQAKYLQDLKDGKQEAAGFRPAWSNNIEMVEAEEGVGISSTRVRNAAKQGKWDIVSELCTESVAAWIKDQELYSEDASGKKMMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5J3</accession>
    <name>W6Z5J3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_37012</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688238.1">
        <property type="nucleotide sequence ID" value="XM_007690048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5J3"/>
    <dbReference type="STRING" id="930090.W6Z5J3"/>
    <dbReference type="GeneID" id="19123163"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37012"/>
    <dbReference type="eggNOG" id="KOG2543">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028223_2_0_1"/>
    <dbReference type="OrthoDB" id="365981at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020796">
        <property type="entry name" value="ORC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047088">
        <property type="entry name" value="ORC5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048866">
        <property type="entry name" value="ORC5_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14630">
        <property type="entry name" value="ORC5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21639">
        <property type="entry name" value="ORC5_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="8">
        <location>
            <begin position="13"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="ORC5 lid" evidence="10">
        <location>
            <begin position="226"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 5 C-terminal" evidence="9">
        <location>
            <begin position="327"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="479" mass="53373" checksum="E09CA785CF995619" modified="2014-04-16" version="1">MLPDEIIAQLDAEFQCRHHQIQHLTALYSAHLPSPPLLNIHGLTATGKSSILRSFFHLSRLCHTIINVRECITTRHLVERIVASTLDALDEFHDEKTDRRSYARTENLSALCVNMGKLLHGRGKFVLVLDAMDKLREGGGTLIAALGRLGESIPNLSIILSTTLPLTPSVLHSSSTLFLHFPTYSRTDLIAILGASPPKIFLNPPSLEQFPDYTLDLAAEDDAWLWGRFLQAVYDSLAKHTGRDLVSFKNCAMRLWQPFVEPILSGQFGTRDFSRLMVNRRHLFQLEDSVLDRIVAVPGTADPVTNDTVTSATPSKKKLSNMTAHTLPYFTTHILIAAYLASYNPPRTDVTYFMKHTDKRKNKRRAPTATSFSVTGKRTGSKHRKISRHLLTPSPFTLDRLLAIFRALLDGTVPQVADLYTQIATLTSMRLLVRAGGAGTNDALEPGARWRVNFGWEYARALGRTVNLEVGEYLVGGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z636</accession>
    <name>W6Z636_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_101968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964042">
        <property type="protein sequence ID" value="EUC43029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690478.1">
        <property type="nucleotide sequence ID" value="XM_007692288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z636"/>
    <dbReference type="STRING" id="930090.W6Z636"/>
    <dbReference type="GeneID" id="19117983"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101968"/>
    <dbReference type="eggNOG" id="ENOG502SI13">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031053_0_0_1"/>
    <dbReference type="OrthoDB" id="5288318at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="424" mass="46852" checksum="F49D7C3143583B80" modified="2014-04-16" version="1">MVVLVDLEDDEAPSLQSPHASGLLNVKPLHHSLSESAAESGQRVNVIDERPNPNKNGFSAALSCYPIVSQLAAQLDLNTLHDLSRTCRQFRANLLEYRSQLVKHTLHCVNEDVEPGETPGSSLQGGRYSMAMESRLTTGRVGICARDMVGECQRCGTIVCRNCTMKPPPTPALRARHRRLCRTCTKAPLPMLMAVQKRRSSSDSSPPGSPDQRPVLFESSQPRAFTAPAFERTPCNCDDVVWFCAPCGKDLRNADTMYVRGWSWRTRYSHYLGGVGTGAGEGNEGVECGRGCACLGARIVEHETCEQDLLDTIERSHTPSSESPDRWRGTSYLTQEIEGIGGVLKMKHKKQVRVGECVKLYEDEKEKSIQYLEREVKGELRSWCSWCERVVLGKKDKAEINGVRPPSSGSSSTASTSSKPLYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6M9</accession>
    <name>W6Z6M9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_64712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686104.1">
        <property type="nucleotide sequence ID" value="XM_007687914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6M9"/>
    <dbReference type="GeneID" id="19124966"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_64712"/>
    <dbReference type="eggNOG" id="ENOG502RV5I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009988_3_1_1"/>
    <dbReference type="OrthoDB" id="4074350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Aspartic_peptidase_A1"/>
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        <property type="entry name" value="PEPTIDASE_A1"/>
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        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
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        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
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    </dbReference>
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        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Asp"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="3">
        <location>
            <begin position="25"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="455" mass="50343" checksum="063C5657DA1A6C66" modified="2014-04-16" version="1" fragment="single">RAGTTAAPISFAPSQYFEGDDGKWSTFVVRVGTPEQSFRVLPSTVSSETFLPMAGACKDDEHMSAVSLIPKDCAFSRGAELYQGRTNNGFQANLSSTWHEIGIYQTMTREELGYNASGLYGLDTLGLMIANSGGPTLENQTIGAVVNPRLWVGRLGMDVKPSNFSDFANPQRSLIKTLHEEGYIPSLSYGYTAGAYYKQPNVYGSLTYGGYDQSRFVPNNVTFPFDANDSRKPCLKIQTIIGQNMSGETISLQETVVPYMLVDFAEPHIWLPVSTCDQFAQAFNLTYDNSTDLYLVDSSTHANLVERNPTITFGLGQTASDLSGRVNIVLPYSAFDQQASYPIYENATNYFPIRRAYNESQYTLGRTFFQEAYIRIDYDRGNFSIHQALFPTSGDKQEVVPVFSPTEISNVQGRKPLSKGGIVGIAIGSILLLAIASFLGQWVWRKRRKAKAPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6Z6</accession>
    <name>W6Z6Z6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_95288</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689768.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z6Z6"/>
    <dbReference type="GeneID" id="19128623"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95288"/>
    <dbReference type="eggNOG" id="KOG0533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="346839at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF35">
        <property type="entry name" value="RNA ANNEALING PROTEIN YRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
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        <location>
            <begin position="69"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="253"/>
        </location>
    </feature>
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        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
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        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC45568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="253" mass="26212" checksum="D14EDEF1DE70FBEF" modified="2014-04-16" version="1">MSSNKMEQSLDDILKASKTSRRGRSSRRSGAGRPAAAPAPVGGVAKSTKQAKPAKAAPAAPAVILAGETKIMVSNLPRDIDQVQLQDYFASAINVGRPKKVLLQYDAAGRSVGSATIIFNKHDQAAKATAALDGVKIDGRPVRVEMLVSPSAIPAAARPASLADRVTQPKKDKPKPATTEKAAAGATRGRGQTRGRGKGRGGRDARPKKKTVEELDAEMADYFPGGETSNAASGAEVAQVTAGGDTAMDDEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7G6</accession>
    <name>W6Z7G6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Biotrophy-associated secreted protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_94092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687529.1">
        <property type="nucleotide sequence ID" value="XM_007689339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7G6"/>
    <dbReference type="GeneID" id="19128390"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94092"/>
    <dbReference type="eggNOG" id="ENOG502SURB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180920_0_0_1"/>
    <dbReference type="OrthoDB" id="2132010at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886545" description="Biotrophy-associated secreted protein 2" evidence="1">
        <location>
            <begin position="18"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="10792" checksum="B61173C4DFB1AD7F" modified="2014-04-16" version="1">MRFTIATLFTLAAMSMAQVTPNNAGAKNVGQGNGAQFITGGCVSDADCSSACCAQVASTGAGVCSAEVASQQNGKTGCGFNDPNASAVIAAAKAQVARQGFKRVVRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7K8</accession>
    <name>W6Z7K8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_26106</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963978">
        <property type="protein sequence ID" value="EUC45748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687719.1">
        <property type="nucleotide sequence ID" value="XM_007689529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7K8"/>
    <dbReference type="GeneID" id="19120878"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26106"/>
    <dbReference type="eggNOG" id="ENOG502SF4J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035048_0_0_1"/>
    <dbReference type="OrthoDB" id="5338512at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889584" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="29"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="47097" checksum="CBB80ACE102E38DC" modified="2014-04-16" version="1">MAPITPSPRLSRISVLCLFIFFITTTQASALFVRQAQTCGGNAELQQCGGDFPSSFCCPKSSTCMNLDSGSVKSVICCPAGSDCSYIQPTTCDVAQLNATLHPENQMHLSGTDGVELPKCGDKCCSLGYTCQGNMCAKDTSPTPSPSNPSTPTPSPSSTSPASASQTSDCPTSTPVETKSSFDGRSFAAGFFPGLVIGALSTIALLWVIKKRRESQSKERYSGDFGHVARQISDPIYDPQLAARTDFMRRGSRSVASSPNSADRIAQGMKESNNTVVHGFTPRIKSMWERTPKLNFGFGLPATPAPPAVRAGNPYNDPYQTPPPKPKRIHSARRTSSRRTSAIPPHVQPQYQQGRPGVGRVDSSETIDVLMPTTGSGYPMNHNNDSGFLQPPQAPGMRGPNRYTTDSAHTTFTKLMERAGFDEEPMQAVRDWKTPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8E1</accession>
    <name>W6Z8E1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">methylated diphthine methylhydrolase</fullName>
            <ecNumber evidence="6">3.1.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_93387</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>diphthine methyl ester-[translation elongation factor 2] + H2O = diphthine-[translation elongation factor 2] + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:42656"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="EC" id="3.1.1.97"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DPH7 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.97" evidence="6"/>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687236.1">
        <property type="nucleotide sequence ID" value="XM_007689046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8E1"/>
    <dbReference type="STRING" id="930090.W6Z8E1"/>
    <dbReference type="GeneID" id="19128260"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93387"/>
    <dbReference type="eggNOG" id="KOG0280">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036100_1_0_1"/>
    <dbReference type="OrthoDB" id="1930760at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061685">
        <property type="term" value="F:diphthine methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052415">
        <property type="entry name" value="Diphthine_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042:SF1">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="379" mass="41545" checksum="5B0BEC7558DD621B" modified="2014-04-16" version="1">MSSIRSLTSFKLDLPPSCIEFFPLNPQYAVVGTYNLEKSDEKDAAGSAPQDGKVSAKNQQRNGSLILVKVDGDNVNIIQTLATPSAILDIHFLTHVTSSNFGVATSTGAFAIYELQSWQRNPSISHIKTIQYFPEDVLITAFSWHPESFMVGMTLSNGQVCLGVIDTEGEDDSPTKLEVATHDLEAWTLAFLPDGSGLLSGGDDSTLRFAELSDGSGGSVPWMDGKIHGAGVTAILPVHLDTQGLLVITGSYDDHLRLVHIPISGRRQVLAETNLGGGVWRLKLLDRNPKLPEHHGVEKWRSEPPPEAILLLVSCMHAGTRIVRLTKSAGEWKIEVLAKFEEHESMNYGSDSQPGLNSQGQRTYISTSFYDRLLCLWRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8E9</accession>
    <name>W6Z8E9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_93296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687242.1">
        <property type="nucleotide sequence ID" value="XM_007689052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8E9"/>
    <dbReference type="GeneID" id="19128245"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93296"/>
    <dbReference type="eggNOG" id="ENOG502T4H2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105487_0_0_1"/>
    <dbReference type="OrthoDB" id="3694481at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886573" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="22775" checksum="1F9646DD8D50E501" modified="2014-04-16" version="1">MQFTTPLFLLVAGVAASPILINVGGLSVGVSSSSGLVSLNSATTKSSDVATSTKTTTTTATTVPTMPSSFSAPVQGKGILTLDNLPAMPPVIDKSLSGVLGVVYGLLSGVCSADFKCTITVAGSIQSLLVDGDKYAMSSSVSAWCDQGRCYGSGDIPLTATAPFIITCDHLTGGTTSACSATISGAASAIFTNGKQIELWGWVTPSGYCKDGICVASISAFGDPMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z944</accession>
    <name>W6Z944_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_87926</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKN1/KRE6 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685256.1">
        <property type="nucleotide sequence ID" value="XM_007687066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z944"/>
    <dbReference type="GeneID" id="19127160"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87926"/>
    <dbReference type="eggNOG" id="ENOG502QR13">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010811_4_1_1"/>
    <dbReference type="OrthoDB" id="412647at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02180">
        <property type="entry name" value="GH16_fungal_KRE6_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005629">
        <property type="entry name" value="Skn1/Kre6/Sbg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361:SF1">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03935">
        <property type="entry name" value="SKN1_KRE6_Sbg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="11">
        <location>
            <begin position="246"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="81"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC48237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="656" mass="72504" checksum="A2B4E95607D979BE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z980</accession>
    <name>W6Z980_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_109333</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z980"/>
    <dbReference type="GeneID" id="19119412"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109333"/>
    <dbReference type="eggNOG" id="ENOG502SMCE">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025694_2_2_1"/>
    <dbReference type="OrthoDB" id="4187847at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000006">
        <property type="entry name" value="Mannan endo-1,6-alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889618" description="mannan endo-1,6-alpha-mannosidase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="611"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="408"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="413"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="428"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="459"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="496"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC40236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="633" mass="67300" checksum="EE455CE3527F4CCA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9G9</accession>
    <name>W6Z9G9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_87751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9G9"/>
    <dbReference type="STRING" id="930090.W6Z9G9"/>
    <dbReference type="GeneID" id="19127121"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87751"/>
    <dbReference type="eggNOG" id="ENOG502S39N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038735_0_0_1"/>
    <dbReference type="OrthoDB" id="5421601at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="499" mass="56782" checksum="40E266BFAA63B74D" modified="2014-04-16" version="1">MGLLDLPPEILDLIIDRTAPDGLENFVLSCRAVYSRAASQIQRHNSLKRTWRHISNLSTTRLRDTLAILHEISREPIIAEYIESLFLWDRGSEDEVMDEDAEYSFRDDDEAMEEIKSLLRRTELYANADENEWWNQILEEDRTHNGSKIDKLYATIALLSLLPNLKVLQLPDRWHETREGEGAEDLVPLVQALVSMSNAPGHRQKPLAQLETLLPFVEEGYDIRVGLQVIEPLMVLKSIRNIYAVSCTAVDEGWGGPGFRWLNPNAKSPLTRVEFASCCMNATGLAGFLSNVPALQVFRYSHQTKWHGVQYDWNPGEVLETLANYCSGTLVDIAITIDELFGEIVNGLSSFLRFTKLERLEVDLECFCGPPLESGQRQGAEARIPEGAVAWRHADIPCMGDMLPDSMRELHVNTNFPQPSEESLLALFKNIVARRQDKLLNLHTAIIRQYRSSSAQYIAQNHQVLIEVFEKDVENPRPRSMMPLWKREFDRRVGGIVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9I9</accession>
    <name>W6Z9I9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Large ribosomal subunit protein mL60</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the mitochondrial large ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964009">
        <property type="protein sequence ID" value="EUC44194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689269.1">
        <property type="nucleotide sequence ID" value="XM_007691079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9I9"/>
    <dbReference type="GeneID" id="19123352"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37920"/>
    <dbReference type="eggNOG" id="ENOG502S81F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141719_0_0_1"/>
    <dbReference type="OrthoDB" id="2332379at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016340">
        <property type="entry name" value="Ribosomal_mL60"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28271">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L31, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28271:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09784">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002216">
        <property type="entry name" value="MRPL31_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR002216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="110" mass="13332" checksum="9C93753F55B6E614" modified="2014-04-16" version="1">MFGPFRLTNPLSGGLLWKVPWRLSRHQKYRHRERLRHVDSVVSTLDTALRRMGQSMKKVERWKTEMPTEEEMLPKDKYTVFDRKVKRYRKGIHKVPKWTRVSQRLNPPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9R3</accession>
    <name>W6Z9R3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxisomal trans-2-enoyl-CoA reductase</fullName>
            <ecNumber evidence="13">1.3.1.38</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_98669</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>(2E)-decenoyl-CoA + NADPH + H(+) = decanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44960"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61406"/>
            <dbReference type="ChEBI" id="CHEBI:61430"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:44961"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2E)-dodecenoyl-CoA + NADPH + H(+) = dodecanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57330"/>
            <dbReference type="ChEBI" id="CHEBI:57375"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:44965"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(2E)-hexenoyl-CoA + NADPH + H(+) = hexanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44956"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62077"/>
            <dbReference type="ChEBI" id="CHEBI:62620"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:44957"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>(2E)-octenoyl-CoA + NADPH + H(+) = octanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44952"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57386"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62242"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:44953"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(2E)-tetradecenoyl-CoA + NADPH + H(+) = tetradecanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44968"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61405"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:44969"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:33763"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.1.38"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:33764"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with PEX5, probably required to target it into peroxisomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.3.1.38" evidence="13"/>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689251.1">
        <property type="nucleotide sequence ID" value="XM_007691061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9R3"/>
    <dbReference type="GeneID" id="19129309"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98669"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_847382_0_0_1"/>
    <dbReference type="OrthoDB" id="414540at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019166">
        <property type="term" value="F:trans-2-enoyl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033306">
        <property type="term" value="P:phytol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052388">
        <property type="entry name" value="Peroxisomal_t2-enoyl-CoA_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24317">
        <property type="entry name" value="PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24317:SF7">
        <property type="entry name" value="PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00041063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC44254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="310" mass="32249" checksum="D223EBA38BEC9D46" modified="2014-04-16" version="1">MNQSNGSGREEGITDSEHFSPYRADGKLYGFVCVVTGATQPVGKAIVAELAAHGAACIYACSTLPSDPYSLPDHTSTQYPNTKIISYPYNMASEEDTLALIDDVLNTWGRLDVWTSSTGLLGPPSITQTGPKDLYAAFDTNALPAFFALKYAPAAMQKTTPKGNYANAAPKDVAYGSIIVVTSVAGTYGGCWAPAFTMASHAALGVVRSGVLVLKGTGVRINAVAAGQIDVGVDLKDCGVKEMAQGQFPPASLQGGESQKRTIGLERAGRPEEVGRTVGFLASGFSSYITGAELRVDGGAGVMNPITVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9W4</accession>
    <name>W6Z9W4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_87108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
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        <property type="component" value="Unassembled WGS sequence"/>
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        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="299"/>
        </location>
    </feature>
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        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="299" mass="31630" checksum="B280DFDD666A94AA" modified="2014-04-16" version="1">MTASLPIIPPPRQQPARPKLSINTEQPRILGKGASLRLDTLSAASPTVRNTYTNAYERPSTAPTLQRPQRPSLSIESDLPAAANSASTPSSASTLSSTLTSASADSATSAIPYKQPHNLVSILSNSPARSILPRKMAASRPMFPAEKHVCFRTPLEEEITTTRYTLAHSDLESSVSTLSTISSVASSTDSDVSAAHHSLIVNTSNTSSTTSISPLQLSLQKSTSTFASAESSPRSKGPRAGDKRDSSSSEDESDSCPQTPIAGRRKRTRDWRWTLGPLPSSDKSSTSSASEATTSDDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA09</accession>
    <name>W6ZA09_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_91778</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_91778"/>
    <dbReference type="eggNOG" id="KOG0254">
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    </dbReference>
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    <dbReference type="OrthoDB" id="2241241at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000044">
        <property type="entry name" value="Hexose transporter Hxt3p"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF39">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
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        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
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        <location>
            <begin position="47"/>
            <end position="496"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
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        <location>
            <begin position="530"/>
            <end position="572"/>
        </location>
    </feature>
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        <location>
            <begin position="544"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC46815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="572" mass="63901" checksum="B914659F0F451023" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAZ0</accession>
    <name>W6ZAZ0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_76143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690659.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19125335"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_76143"/>
    <dbReference type="HOGENOM" id="CLU_1859944_0_0_1"/>
    <dbReference type="OrthoDB" id="2150604at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15248" checksum="9AB2FB23F8BA0783" modified="2014-04-16" version="1" fragment="single">RWRSSKLSELTVVIITGALIAGVVSSAFSWPTINDAPWTAKALLYSALILSLTSISIGTQQSIALYRIGGHEDGLETLQALLKSPRGKNASKLQLYIWQVPVMMLNIAILVFLIGLMVLIWARAAEQPSWDQDMRVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB76</accession>
    <name>W6ZB76_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bacteriophage T5 Orf172 DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_23228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684396.1">
        <property type="nucleotide sequence ID" value="XM_007686206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB76"/>
    <dbReference type="STRING" id="930090.W6ZB76"/>
    <dbReference type="GeneID" id="19120394"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23228"/>
    <dbReference type="eggNOG" id="ENOG502QWMU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024511_1_0_1"/>
    <dbReference type="OrthoDB" id="2417614at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053006">
        <property type="entry name" value="Meiosis_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094:SF2">
        <property type="entry name" value="BACTERIOPHAGE T5 ORF172 DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10544">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00974">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage T5 Orf172 DNA-binding" evidence="2">
        <location>
            <begin position="371"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="516" mass="56447" checksum="40B82E3EF502CC8F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBP3</accession>
    <name>W6ZBP3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">prephenate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_46386</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>prephenate + H(+) = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="2"/>
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        <property type="protein sequence ID" value="EUC47218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686258.1">
        <property type="nucleotide sequence ID" value="XM_007688068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBP3"/>
    <dbReference type="STRING" id="930090.W6ZBP3"/>
    <dbReference type="GeneID" id="19124315"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_46386"/>
    <dbReference type="eggNOG" id="KOG2797">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035008_5_1_1"/>
    <dbReference type="OrthoDB" id="983542at2759"/>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04905">
        <property type="entry name" value="ACT_CM-PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13532">
        <property type="entry name" value="PBP2_PDT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000034">
        <property type="entry name" value="Chorismate mutase/prephenate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022">
        <property type="entry name" value="PREPHENATE DEHYDRATASE P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022:SF19">
        <property type="entry name" value="PREPHENATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00857">
        <property type="entry name" value="PREPHENATE_DEHYDR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="9">
        <location>
            <begin position="11"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="258"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="356" mass="39033" checksum="0B6DB9BD72D08050" modified="2014-04-16" version="1" fragment="single">MTGVEEKKKSVVAYLGPEGSYTHQAALSTFPPQDPPTTTLTPLTTIQDVFTAVQSRTAHLGVVPFENSSNGSVLFTLDLFADSSKQHADILVCDEAYVAVRHCLLGHHPFTPSSSTGTEEDFSHIKRIYSHPQAWGQCKNFLTTHFRNVEKIDVSSTSRAAQIAAEDATGTSAALSSPVAAGIFGLQVLAEGVNDRLGNMTRFLILRRRRRRQQQQQQRQSSPSSSPGLLLLSTPSPPTQNITHAKGNKRHDHWKSLVTFTVHHSNPGALANCLTAFSDQGINLTSINTRPSGDRNWHYVFFVELKGRSRRDEGDGGGEGEGEEEGPVDRALEALGKASSGYRWLGSWENRLEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC34</accession>
    <name>W6ZC34_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_29901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964110">
        <property type="protein sequence ID" value="EUC41286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692183.1">
        <property type="nucleotide sequence ID" value="XM_007693993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC34"/>
    <dbReference type="GeneID" id="19121587"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29901"/>
    <dbReference type="HOGENOM" id="CLU_2276981_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="102" mass="11337" checksum="A6CF714F7FAC12E2" modified="2014-04-16" version="1">MYADVPGNYLALLIYGYYIKLHTTPTPKRKRTILRARCNTIIPAGTGASMAADIYFSLDHLFQSLPIPTEDEEPNDLPAGAPFIVEPPDDDTEIQRADVSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC60</accession>
    <name>W6ZC60_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Caffeine-induced death protein Cid2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_3507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIX23 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685903.1">
        <property type="nucleotide sequence ID" value="XM_007687713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC60"/>
    <dbReference type="STRING" id="930090.W6ZC60"/>
    <dbReference type="GeneID" id="19122703"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3507"/>
    <dbReference type="eggNOG" id="KOG4613">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081050_1_0_1"/>
    <dbReference type="OrthoDB" id="5593818at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019171">
        <property type="entry name" value="MIX23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016805">
        <property type="entry name" value="MIX23_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31905">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31905:SF2">
        <property type="entry name" value="PROTEIN MIX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09774">
        <property type="entry name" value="MIX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022603">
        <property type="entry name" value="UCP022603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21858" checksum="EE993BD0999A69A3" modified="2014-04-16" version="1">MSKPSAQPHLTPQFCFNQTALRDFLRISRSSIDDSITQNLNALLTPAQRGFDPNSTSTRQLSPPGHARVLEPEQCEGFKEKVLFPSWAVRSDVLDYCAGVATSPDPDDPDSLLRQIEDAKARERTVDERLDPYSGRYFPAEARTESLANLMRNERAVEKIIRMRTWSVLGERCGISSESADDAFDKWRVARQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCV6</accession>
    <name>W6ZCV6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_34697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685673.1">
        <property type="nucleotide sequence ID" value="XM_007687483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCV6"/>
    <dbReference type="GeneID" id="19122618"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34697"/>
    <dbReference type="eggNOG" id="ENOG502SCCK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_24_1_1"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="217" mass="24016" checksum="8A2ED3A2345908F6" modified="2014-04-16" version="1">MIPSKISTDRLTLVRLTNTHPSHPHVQLFHENWSNPTATAWSLRGTTHSLAESREWMIESLDRFDNYFYAVFEGDEEDELGVHIGSVSLRLQPSGPTLPPLSLSRHIGSPDPEKQKGSGEDDIPLRALGYAIFPTAWGKGYGTEANRGLLNAYSAAVAQQSGGKGRVYVEAAVDDENAGSLALIQKLGFERVGWKESEKVWLNGGWRGGYWVYGLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD14</accession>
    <name>W6ZD14_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Translation machinery-associated protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_40215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TMA16 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964093">
        <property type="protein sequence ID" value="EUC41636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691848.1">
        <property type="nucleotide sequence ID" value="XM_007693658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD14"/>
    <dbReference type="STRING" id="930090.W6ZD14"/>
    <dbReference type="GeneID" id="19123837"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40215"/>
    <dbReference type="eggNOG" id="ENOG502RY79">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106785_1_0_1"/>
    <dbReference type="OrthoDB" id="270284at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.170">
        <property type="entry name" value="Translation machinery-associated protein 16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021346">
        <property type="entry name" value="Tma16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038356">
        <property type="entry name" value="Tma16_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13349">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13349:SF2">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11176">
        <property type="entry name" value="Tma16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="20817" checksum="E546791ACBD230AE" modified="2014-04-16" version="1">MVSNRLDKVHKQIAKKKGKNPNLHEGSRDTKRLQSAAQRDDKLNRLSKIRENQNRTYLSRIKSFQSYTTEHESPLSVAEIQAMIEDYVGRDDEELAKLKAERRPGRPPSTRQNLLEINQKTERDEYASGFWVPDLEDAANLRKLKEWNGMWAQLAILKFCRISKEGFKRESSFPPKGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDU2</accession>
    <name>W6ZDU2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_88271</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685451.1">
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            <begin position="206"/>
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        </location>
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        </location>
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        </location>
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        </location>
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            <begin position="461"/>
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        <source>
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        </source>
    </evidence>
    <sequence length="618" mass="68243" checksum="23070794C5054A22" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">ATCC 44560</strain>
        </source>
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    </feature>
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        </source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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    <accession>W6ZEA2</accession>
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        </submittedName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
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                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
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        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="55" mass="6348" checksum="13C8853245838BFC" modified="2014-04-16" version="1">MVRREGQHGWLLPTNKPPKTLERNPARHSVRRFSRKRTMGAKGFTQQGVPDHAEV</sequence>
</entry>
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    <accession>W6ZED4</accession>
    <name>W6ZED4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_87487</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="4149149at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="371" mass="43055" checksum="90F62B888D6F93BC" modified="2014-04-16" version="1">MATLRDTPRQPREGYLNLTRRMENEEQDQFDVDLTILDFLVFKATGLIFEWKSSSDPYHSDLPNALVNMTAVDWRVFLGHRHQGRCLDPKASFRSRLLQFALLFTHRLHHTETWTTEASLNSLRDQNKSRGEYWRQRTQHPPALEQPFDQHKDFPLSDGALYENRSELASALRMPMDQRRWVTDVASTPSLHCLLPVFIELTAARATLDDTWLPTSKWYDLAAQFMLQAVIGEYLRNGSYGPETFNTIFSYGCPGVERWADEPTDVSAMRILFCDPDNQRQENREWTRIKRRYIDELLPKDRAQSSLQALQAAQQRYPYAAFERALLAFLQSLHEGLVKPDLAQVEEGRINIDGSELSEAESRAMIRRMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZES3</accession>
    <name>W6ZES3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_25886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963973">
        <property type="protein sequence ID" value="EUC46009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687461.1">
        <property type="nucleotide sequence ID" value="XM_007689271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZES3"/>
    <dbReference type="GeneID" id="19120841"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25886"/>
    <dbReference type="HOGENOM" id="CLU_1175232_0_0_1"/>
    <dbReference type="OrthoDB" id="10452205at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="236" mass="25592" checksum="C3522B24E4B6048D" modified="2014-04-16" version="1">MGCPWPVYSSNVTASLLASTPRPSQEGKSNGRIRVQCDHMRCLQDAVHGAVQQDRDTSTVGRMLCSLSDFLVPCLFNGRRGSWWTRCPKRSSLSARSYLIDLCDQELHNADAPPLIQQQHGLPIATPAPAPAPAPAPAPAPAPAPTRKSNASRIPATLCFCAPMLHKPSSAPTRSPQSAVWGAEHVHPLDRHCALSIMQLLKLYALTTATEQPGGDLHDAIPRLRLPRAYLLVRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEW9</accession>
    <name>W6ZEW9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_78577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964075">
        <property type="protein sequence ID" value="EUC42056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691449.1">
        <property type="nucleotide sequence ID" value="XM_007693259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEW9"/>
    <dbReference type="GeneID" id="19125411"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_78577"/>
    <dbReference type="HOGENOM" id="CLU_2984399_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="58" mass="6463" checksum="1FA71E3C054E959F" modified="2014-04-16" version="1" fragment="single">TLDTALRMLQSRLTTPLSNAKQPAAIRLLRELSHLPLPCPTTSRTPPPRAHHHLAHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF10</accession>
    <name>W6ZF10_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_86880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684851.1">
        <property type="nucleotide sequence ID" value="XM_007686661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF10"/>
    <dbReference type="GeneID" id="19126947"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86880"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_13_1_1"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05323">
        <property type="entry name" value="ADH_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF10">
        <property type="entry name" value="NAD(P)-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="282" mass="29639" checksum="BFD52F095CF3FA3F" modified="2014-04-16" version="1">MASFEINDSDLTGFQGKVAIITGGSSGIGLATVELLVSLGALVVSGDIQPPPASNANCHFVQTDVRNWADLTKLFKAAKEKHGKIDFVFANAGIGPRANYLALEVDANGDPIEPNQDTIDINLDSVVKTVTIAAHYLKTQPEGGSIVIMGSSTGLHPVRAVDYSTAKAGVLGFGRSFARLVEVAGLPIRVNTLAPSWTATQVLPDLKNLLAAVSHDCQTPDVVARAVAYLMVDKSRHGELIFASNGKYTEIQNTILAPAYEAIKGDDLSDDAVLAKVMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF37</accession>
    <name>W6ZF37_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_8247</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964072">
        <property type="protein sequence ID" value="EUC42126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691342.1">
        <property type="nucleotide sequence ID" value="XM_007693152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF37"/>
    <dbReference type="GeneID" id="19126059"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8247"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:001331">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF21">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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    </feature>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1068"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1512"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1531"/>
            <end position="1543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1567"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1577"/>
            <end position="1589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1606"/>
            <end position="1620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00037935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC48950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1772" mass="195794" checksum="5F5F9649FA155A60" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGE1</accession>
    <name>W6ZGE1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF7707 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_80520</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682580.1">
        <property type="nucleotide sequence ID" value="XM_007684390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGE1"/>
    <dbReference type="GeneID" id="19125687"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80520"/>
    <dbReference type="eggNOG" id="ENOG502S9NN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084512_0_0_1"/>
    <dbReference type="OrthoDB" id="2439692at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056124">
        <property type="entry name" value="DUF7707"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118:SF2">
        <property type="entry name" value="CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24808">
        <property type="entry name" value="DUF7707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890005" description="DUF7707 domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7707" evidence="4">
        <location>
            <begin position="28"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="211" mass="22088" checksum="C93EB606FB29CDBC" modified="2014-04-16" version="1">MRSIFALGIAALTGFTAAQTTPQMNYPYTIDPDTVPQSTRDYWCSQNTAQCPLICLQQPGVNSMSTEANDCDSDNLTYNCVCDNGVSPNITEYSQTLPFFICQQWGNNCVDNCGNDPACQSACRQDHPCGAQQPYRGNTSLPTTMASTAKPSGTASNTIPVTGFGGAEPTGSSGSNSGNNNKGAGSLFMPNAGLGLAALFGSVFFGFAVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH91</accession>
    <name>W6ZH91_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_49315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684088.1">
        <property type="nucleotide sequence ID" value="XM_007685898.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZH91"/>
    <dbReference type="GeneID" id="19124433"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_49315"/>
    <dbReference type="eggNOG" id="ENOG502RITK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064359_0_0_1"/>
    <dbReference type="OrthoDB" id="3692348at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="30862" checksum="5845B2C85364F95B" modified="2014-04-16" version="1" fragment="single">SPLLNAIKLGNLRILKKLIKYLQSSQITEAHRDTLFNNPLANFCIYKAIGKSITYSRDDMFLMVTKLIRRKFGGLKPRDFDAFVRLVVKTSNVRMLRYLFRIPTSPAWVLTQNTMCAICNSAEYDLIYFVFRKADCANAHRTSRRHPLHIAVRAGLEATRAVYDTGKYDVNESVSWPYKGYWDEPVTALDVAIFRHDHAIVKWLLDHGANYRRRFPSFYMSCRIFNYIRDRAIVDDPRMVDLPSYGQYSDMCREARDSFVFGLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHZ5</accession>
    <name>W6ZHZ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TMEM205-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_84112</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683909.1">
        <property type="nucleotide sequence ID" value="XM_007685719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHZ5"/>
    <dbReference type="GeneID" id="19126397"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84112"/>
    <dbReference type="eggNOG" id="ENOG502S3VC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094297_2_1_1"/>
    <dbReference type="OrthoDB" id="1641132at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025423">
        <property type="entry name" value="TMEM205-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053009">
        <property type="entry name" value="Xanthocillin_Biosynth-Assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23241">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT PLANTS LEA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23241:SF102">
        <property type="entry name" value="LD23009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13664">
        <property type="entry name" value="DUF4149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM205-like" evidence="6">
        <location>
            <begin position="16"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC49615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="165" mass="18115" checksum="776457489BAF3811" modified="2014-04-16" version="1">MLHSIVSAVLPSVHLLAYSALIGTELYQTFVVTKITYRALPRPAFVGLQKQLFPAYFNAQFLLLLVVALTRPPYGPFSSFGEPASCIPFAVAGVTGGLNFGLYGPRSRALMIERATKATRDSKSEEKLLLNKAFSRAHAISIHLNLVTIGATLWYGWQLASKLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHZ8</accession>
    <name>W6ZHZ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA mismatch repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_3903</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686378.1">
        <property type="nucleotide sequence ID" value="XM_007688188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHZ8"/>
    <dbReference type="STRING" id="930090.W6ZHZ8"/>
    <dbReference type="GeneID" id="19123602"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3903"/>
    <dbReference type="eggNOG" id="KOG0217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_1_0_1"/>
    <dbReference type="OrthoDB" id="10252754at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032137">
        <property type="term" value="F:guanine/thymine mispair binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032138">
        <property type="term" value="F:single base insertion or deletion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043570">
        <property type="term" value="P:maintenance of DNA repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000710">
        <property type="term" value="P:meiotic mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000019">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000006">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000002">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000771">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="12">
        <location>
            <begin position="1048"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="199"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR037677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC47044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1213" mass="135488" checksum="ED0D4BAF0643749B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI19</accession>
    <name>W6ZI19_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_35365</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAPRTase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="3"/>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686416.1">
        <property type="nucleotide sequence ID" value="XM_007688226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI19"/>
    <dbReference type="STRING" id="930090.W6ZI19"/>
    <dbReference type="GeneID" id="19122767"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35365"/>
    <dbReference type="eggNOG" id="KOG2511">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030991_0_0_1"/>
    <dbReference type="OrthoDB" id="193380at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034355">
        <property type="term" value="P:NAD+ biosynthetic process via the salvage pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019358">
        <property type="term" value="P:nicotinate nucleotide salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000183">
        <property type="term" value="P:rDNA heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.140.10">
        <property type="entry name" value="nicotinate phosphoribosyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041525">
        <property type="entry name" value="N/Namide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040727">
        <property type="entry name" value="NAPRTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098">
        <property type="entry name" value="NICOTINATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098:SF1">
        <property type="entry name" value="NICOTINATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04095">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17767">
        <property type="entry name" value="NAPRTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000484">
        <property type="entry name" value="NAPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54675">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nicotinate phosphoribosyltransferase N-terminal" evidence="9">
        <location>
            <begin position="16"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Nicotinate/nicotinamide phosphoribosyltransferase" evidence="8">
        <location>
            <begin position="181"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Nicotinate/nicotinamide phosphoribosyltransferase" evidence="8">
        <location>
            <begin position="341"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="487" mass="53962" checksum="55B4FD37CFD56F94" modified="2014-04-16" version="1">MAAESATLPEGIFSLLDTDLYKLTMQCCILKFFPDVAVTYGFTNRTPDKKLSRAAFKWLQAQVDKLENVSVSDEELKFLKDSCPYLNAQYLHFLSTFRLKPSKQLRLSFTPVNDTGSDSDYGDFHIHTEGLWLDTILYEIPLLALVSEAYFKFVETDWNHEGQVEKAYQKGKALLEGGCIFSEFGSRRRRDYHTQDLVLQGLRRAADEGAKIGWKGKLSGTSNVHFAMKHGLVPVGTVAHEWFMGVAAITNNYEKANEIALEYWTATFGAGVLSIALTDTFGTPAFLRAFKQHIPRVTTAVPGGSTTLPSSGNTTTSDAVETLASTNPPVQAPYNGDAASETTYAQVFNGVRQDSGDPLEFIKLMREFYDKEGIKDKKTIVFSDSLNLELCFKYKAAAEEQGFQPTFGVGTFLTNDFVETSTGKKSVPLNIVIKIASAQGRHAVKISDNIGKNTGDQATVDEVKQRLGYQEKSWIGGDERTRWGSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIA7</accession>
    <name>W6ZIA7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mitogen-activated protein kinase kinase kinase</fullName>
            <ecNumber evidence="2">2.7.11.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_7335</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.25" evidence="2"/>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690252.1">
        <property type="nucleotide sequence ID" value="XM_007692062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIA7"/>
    <dbReference type="STRING" id="930090.W6ZIA7"/>
    <dbReference type="GeneID" id="19125258"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7335"/>
    <dbReference type="eggNOG" id="KOG0198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003051_1_2_1"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09534">
        <property type="entry name" value="SAM_Ste11_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000334">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000214">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029458">
        <property type="entry name" value="Ras-bd_By2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14847">
        <property type="entry name" value="Ras_bdg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01304">
        <property type="entry name" value="Ras_bdg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM" evidence="13">
        <location>
            <begin position="68"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="684"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="127"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="713"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC43236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="959" mass="104772" checksum="F727320CAA85D3A7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIM5</accession>
    <name>W6ZIM5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Imidazole glycerol phosphate synthase hisHF</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">Glutaminase</fullName>
                <ecNumber evidence="12">3.5.1.2</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">Cyclase</fullName>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_83723</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">In the C-terminal section; belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="12"/>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683679.1">
        <property type="nucleotide sequence ID" value="XM_007685489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIM5"/>
    <dbReference type="STRING" id="930090.W6ZIM5"/>
    <dbReference type="GeneID" id="19126312"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83723"/>
    <dbReference type="eggNOG" id="KOG0623">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037550_0_0_1"/>
    <dbReference type="OrthoDB" id="10254903at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000094">
        <property type="entry name" value="Imidazole glycerol phosphate synthase hisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000039">
        <property type="entry name" value="Imidazole glycerol phosphate synthase hisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050064">
        <property type="entry name" value="IGPS_HisA/HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014640">
        <property type="entry name" value="IGPS_HisHF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235:SF2">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF/H IGP SYNTHASE SUBUNIT HISF/H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036936">
        <property type="entry name" value="IGPS_HisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 12 15" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="16">
        <location>
            <begin position="6"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="360"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="398"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="470"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="496"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="PRFAR binding" evidence="14">
        <location>
            <begin position="519"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="13">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR036936-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR036936-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC49813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="550" mass="59901" checksum="B71BECE46BFCEAF6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIV5</accession>
    <name>W6ZIV5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MADS-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_27992</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MEF2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964026">
        <property type="protein sequence ID" value="EUC43531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689938.1">
        <property type="nucleotide sequence ID" value="XM_007691748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIV5"/>
    <dbReference type="STRING" id="930090.W6ZIV5"/>
    <dbReference type="GeneID" id="19121222"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27992"/>
    <dbReference type="eggNOG" id="KOG0014">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024080_1_0_1"/>
    <dbReference type="OrthoDB" id="1898716at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008301">
        <property type="term" value="F:DNA binding, bending"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00265">
        <property type="entry name" value="MADS_MEF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1810.10:FF:000013">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050142">
        <property type="entry name" value="MADS-box/MEF2_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033896">
        <property type="entry name" value="MEF2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48019">
        <property type="entry name" value="SERUM RESPONSE FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00350">
        <property type="entry name" value="MADS_BOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="73"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="250"/>
            <end position="293"/>
        </location>
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        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="358"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
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            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="507"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="609" mass="66792" checksum="9657F549C3EA92E5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJE2</accession>
    <name>W6ZJE2_COCMI</name>
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        <recommendedName>
            <fullName evidence="11">Ubiquitin-conjugating enzyme E2 Z</fullName>
            <ecNumber evidence="3">2.3.2.23</ecNumber>
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        <alternativeName>
            <fullName evidence="12">E2 ubiquitin-conjugating enzyme Z</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ubiquitin carrier protein Z</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquitin-protein ligase Z</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_89662</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="16 17">ATCC 44560</strain>
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    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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        <subcellularLocation>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZJE2"/>
    <dbReference type="GeneID" id="19127519"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89662"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:cysteine-type endopeptidase inhibitor activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ubiquitin conjugating enzyme, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF26">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2 Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="UBCc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="15">
        <location>
            <begin position="4"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="15">
        <location>
            <begin position="286"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00041798"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00042316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC47594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="439" mass="50727" checksum="15FA604D066D7DB5" modified="2014-04-16" version="1">MSNQCILRITRELGEIQRGSDLSIAVACRDIDVRHVRALIIGPPDTPYEFGFFEFAVKFTRDYPTKAPSVTAITTNGGRTRFNPNIYAGGKVCLSILGTWRGERGEEWSSAQGLESILISIQSLMSGNPYENEPGFEDANSDYDKKNQEAYVDKIRHESLRISVIERLEEYLGINRQRPGVTIYNAEEDYQSNRDDAPFEPFKDLCKRRFLWYYQSYLTRVDEAVKQNKDGDRFEKMPFEGPGNTMEGIFQYTSLRERLVKIFETLNKEMESWALEGMSAVKKEMSIANNLQRQYEQIVEKYKKQDAIALDLDLVDKNPFVWQLVLFGRPMTNLDGGMFRIRLYISPKFPDVLPRVRFETPILYHHRVSPDGILCYDAARKDDMRSHIEAIIAAIEEESPAYDPRTLVNPEAAKLFWGSPEDKKLYNRRLRRSAQDSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJZ0</accession>
    <name>W6ZJZ0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PARP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_76408</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689571.1">
        <property type="nucleotide sequence ID" value="XM_007691381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJZ0"/>
    <dbReference type="STRING" id="930090.W6ZJZ0"/>
    <dbReference type="GeneID" id="19125344"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_76408"/>
    <dbReference type="eggNOG" id="ENOG502S5PB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150769_0_0_1"/>
    <dbReference type="OrthoDB" id="429950at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00645">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC43906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="95" mass="10932" checksum="D8CF4E624D260B6B" modified="2014-04-16" version="1" fragment="single">EVSPNNRAGCQVKACKDEGKKITKGEFRFAVQVTIHEHVSWQYRHWGCVTPKQIENLNETCGGDTDMVDGYDELPEEFQEKVKFALEHNHIPDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK79</accession>
    <name>W6ZK79_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682985.1">
        <property type="nucleotide sequence ID" value="XM_007684795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK79"/>
    <dbReference type="GeneID" id="19120164"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22027"/>
    <dbReference type="eggNOG" id="ENOG502R90Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042936_0_0_1"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="55165" checksum="50BD8CF50EB12F6F" modified="2014-04-16" version="1">MASTAAAKRDSMDATASGLEAKTKAASLEQPTRKRPLGLTDLPPSVRNNIYRYCLDTEMVNLGEPNVSYTHKIGDGVLKFSASRKPFPINSSLFYVNTAFSKDALRYFYKKNLWVRLDVYTADARHAKTLLEDSGLLFSTASPEAVEKAIQHALEVVLVEKNSAQKRASVMFPAQYLPRLINFFDQASRATATWAPMHTLFLTVMNTYDFPISRLQGDLLEPFRLLSNFGGVTVDSNNLLPRYAEGLQSMMTEKSFTAESYLAHVTELADLSDSAREKEDYTLANEYANAVIIALTYGYLTHPEILHSQDESFSKAIQRLRWRTELGLGISLSIPLRSLTSTKHWMHTPNPTPEIKKAARDLLLAETSVSKALSLVTDSPSPASNPWFHSLPIELIPNNKPTFFSEREKAQTWYALGTVHMALGENIFACGDMERALELWGKESGVDEEDGLRGRIEEAFERARKGIDGDAESMWVGEIRPGTGLKKAARLARGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKP5</accession>
    <name>W6ZKP5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_32089</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682850.1">
        <property type="nucleotide sequence ID" value="XM_007684660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKP5"/>
    <dbReference type="GeneID" id="19122023"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32089"/>
    <dbReference type="eggNOG" id="ENOG502S3AV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042307_1_0_1"/>
    <dbReference type="OrthoDB" id="9975959at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070260">
        <property type="term" value="F:5'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051547">
        <property type="entry name" value="TDP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15822">
        <property type="entry name" value="TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15822:SF4">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC50568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="33389" checksum="65C4F47E1AD717E6" modified="2014-04-16" version="1">MLSQIRTNIQSWWQQTPLPTNTAPPSFQKWHIFDQDQWISFVSDGNSQPDIKHQLAGSFRLVTWNVNADALSPKSRISALLEVIKTTGAVNVIFLQEVSKDALTALLEEPWIQKIAPSGEPPLPSRFGRDALCCDLILNSSSKHIPDKSPLQIRLINVHLDSLPINPSLRPHQLSICTSYLSTAGRGIIGGDFNPVLPEDDGLVYANYLIDAWECIHPNDAGHTWGVYGEHVFPPNRFDKVTLFNLTPSAMGILRTSEVESHGEKMSAGGTKLAEKVQFSDHFGVWCEVRWEENRAQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKQ5</accession>
    <name>W6ZKQ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NECAP PHear domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_81688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682897.1">
        <property type="nucleotide sequence ID" value="XM_007684707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKQ5"/>
    <dbReference type="STRING" id="930090.W6ZKQ5"/>
    <dbReference type="GeneID" id="19125917"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81688"/>
    <dbReference type="eggNOG" id="KOG2500">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069884_0_0_1"/>
    <dbReference type="OrthoDB" id="10265489at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000465">
        <property type="entry name" value="Adaptin ear-binding coat-associated protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012466">
        <property type="entry name" value="NECAP_PHear"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847">
        <property type="entry name" value="ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847:SF9">
        <property type="entry name" value="NECAP-LIKE PROTEIN CG9132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07933">
        <property type="entry name" value="DUF1681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NECAP PHear" evidence="2">
        <location>
            <begin position="16"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="286" mass="30764" checksum="F2971923C6E629B9" modified="2014-04-16" version="1">MNVDPLTGAPLPSTAIQRILYLAPKVHIYQIPPATSTKGYQASMWTANNNQLQIFTARLRIVETSIPSASSDDASGADDNEKVTTTLLLEDPKNGDLFAAAPYTSERTVEQALDSSRFFAITVVGEGRKAVLGMGFEERSEAFDFSIALQDARRVLGFESKSASSLSSRSSSKTSAPVAEEAKRDFSLKAGETISINLGGLKGRRSRSHESDKSDEGKKSDQDALFSIKPPPGSGPGGAFLPPPPSAKSVKEERRRSRQTFDAASLPPKQTAEDLGFDDGEFGEFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKU9</accession>
    <name>W6ZKU9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_21973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682840.1">
        <property type="nucleotide sequence ID" value="XM_007684650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKU9"/>
    <dbReference type="STRING" id="930090.W6ZKU9"/>
    <dbReference type="GeneID" id="19120153"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21973"/>
    <dbReference type="eggNOG" id="KOG2102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002512_0_1_1"/>
    <dbReference type="OrthoDB" id="2285229at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057912">
        <property type="entry name" value="OB_CYT4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056625">
        <property type="entry name" value="SH3_CYT4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056624">
        <property type="entry name" value="WH_CYT4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF65">
        <property type="entry name" value="EXORIBONUCLEASE CYT-4, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25522">
        <property type="entry name" value="OB_cyt-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23214">
        <property type="entry name" value="SH3_CYT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23216">
        <property type="entry name" value="WHD_CYT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="2">
        <location>
            <begin position="543"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1045" mass="117482" checksum="40273540C8EDFDC4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLL0</accession>
    <name>W6ZLL0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_56280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682790.1">
        <property type="nucleotide sequence ID" value="XM_007684600.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLL0"/>
    <dbReference type="STRING" id="930090.W6ZLL0"/>
    <dbReference type="GeneID" id="19124676"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_56280"/>
    <dbReference type="eggNOG" id="KOG0502">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_18_5_1"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="18"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="113" mass="11787" checksum="6329DB1B4C28105F" modified="2014-04-16" version="1" fragment="single">VLLDRGAEVNADGVLYGTVLQAACTSGHKAVIELLLDRGADVNARGGHFETALQAACYHGCRDIVELLLERGAGVNAQGGQYGSALRAASYWGYKTVVELLVANGAKQDETGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLQ5</accession>
    <name>W6ZLQ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_97993</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ZNF598/HEL2 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688943.1">
        <property type="nucleotide sequence ID" value="XM_007690753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLQ5"/>
    <dbReference type="STRING" id="930090.W6ZLQ5"/>
    <dbReference type="GeneID" id="19129162"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97993"/>
    <dbReference type="eggNOG" id="KOG2231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008515_1_0_1"/>
    <dbReference type="OrthoDB" id="3838338at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16615">
        <property type="entry name" value="RING-HC_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057634">
        <property type="entry name" value="PAH_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041888">
        <property type="entry name" value="RING-HC_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056437">
        <property type="entry name" value="Znf-C2H2_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044288">
        <property type="entry name" value="ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938">
        <property type="entry name" value="ZINC FINGER PROTEIN 598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23202">
        <property type="entry name" value="PAH_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25447">
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</entry>
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    <accession>W6ZM29</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wang R."/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="403" mass="41973" checksum="7791F2981B6C4B2E" modified="2014-04-16" version="1">MTSTPSLRQSLTAVVLAALPLASAQGTTPPKLTADCIDVAIFMARGNDAPYHDGRTSPFSDATCAKFQAKGITCDYMDVVFDGTLGVPYCPTIQEGAVNGVRQITEYNAKCPDTLLVLNGYSQGAMVGGAILSGGGEDACDVDPQTTGLDPKSKAGQALKAVLLWGDVKHTANQPYNVLDGADKQVWPRTGANLERMNGFSSVLRSYCAAGDPICAGGTNVAQHLNYFELYTDESSSWVVDKLTPLLAKPSSSSVLSSSATPTPTPTPSPEPTPTPAPTSAASTSEVSSTEPSSTVVVPEPSIPVTSSDIQSTSTAPGTTAHPITIIPTSAHYGNSTIPASSYINTPVQPHETPSLPAGHVSYPAVPPPVPTKAPGYPAHPPVCPPVLVYETVTEYAYVYEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN93</accession>
    <name>W6ZN93_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_86013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684564.1">
        <property type="nucleotide sequence ID" value="XM_007686374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN93"/>
    <dbReference type="GeneID" id="19126786"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86013"/>
    <dbReference type="HOGENOM" id="CLU_2885439_0_0_1"/>
    <dbReference type="OrthoDB" id="3692680at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="63" mass="7078" checksum="AC545CAFACD4CCE5" modified="2014-04-16" version="1">MRTMYLRILFPAFHFHILSLGNVFWTGFRNLARKKRGKSGGQHGYGESLDTAGSTLKSTLDSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPE7</accession>
    <name>W6ZPE7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963983">
        <property type="protein sequence ID" value="EUC45486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687995.1">
        <property type="nucleotide sequence ID" value="XM_007689805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPE7"/>
    <dbReference type="STRING" id="930090.W6ZPE7"/>
    <dbReference type="GeneID" id="19128635"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95332"/>
    <dbReference type="eggNOG" id="ENOG502RYJ9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032662_2_0_1"/>
    <dbReference type="OrthoDB" id="5440at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436:SF3">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="POLYKETIDE CYCLASE SNOAL-LIKE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="46541" checksum="B56C0FF3BC68360E" modified="2014-04-16" version="1">MAQQFLADRNGWLSFRSSTPLLYITAEDAEFDVQTMKAWRDEGFVVEYIPMGNGGKQYVQTLHKLGENMSIGERYAIVAFGDAAAVCLDIFSEPRAATSKLCSLIAYYPTSIPDTRHRFTSSFRVLVHLAEGASGNECTVGVVRRPEVLGIQGKRKTVQKRVTPGIGVGGLQDKILYPCFTYEGVDAGFAEHDLPEYDAVADALAWSRSLSTVRKGFSAEVDLERVLEQNEEQKFHGKAVDKLLETYTRSPRPSINFTPTMTGGIGVSDLKRFYRDYFLRSCPPSLHMRLISRTIGADRIVDEIYFNFKHTCQMPWILPGVPPTNEKVEIVVISIVGFRAGKIWSERLYWDQASVLFQVGLLDPEEVPKEFKGKAKSGDDEDGDGGLEMLPVSGSEAARKVMDIESEEFNDMIDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPU6</accession>
    <name>W6ZPU6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_26195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687812.1">
        <property type="nucleotide sequence ID" value="XM_007689622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPU6"/>
    <dbReference type="GeneID" id="19120897"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26195"/>
    <dbReference type="HOGENOM" id="CLU_1161756_0_0_1"/>
    <dbReference type="OrthoDB" id="3795220at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890158" evidence="2">
        <location>
            <begin position="17"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="244" mass="24158" checksum="B12CA6AA3DEA4CE6" modified="2014-04-16" version="1">MSKIFSTALLVSCATAQLTTSAWMAGTGSNSLSYVASVITVQNGRTTMSIDVQGMTEDLGAAAEIGQMVTLQGNTYYGVNAVAENDGVTVTITGECTRQNTDDQEATCTMSTKGLEAAVSSACASADSEDELCSAGPLDTSATTTLPDGYFNMVQVVVTAGEDLLPSASAAATPSAGSASLTSSKSSATNSAKPTSSGSEAPASSGASRTSQTSSAAPEATNAAPLMNVVPALAGLGAAAAFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ01</accession>
    <name>W6ZQ01_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_5125</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687753.1">
        <property type="nucleotide sequence ID" value="XM_007689563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ01"/>
    <dbReference type="STRING" id="930090.W6ZQ01"/>
    <dbReference type="GeneID" id="19124502"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5125"/>
    <dbReference type="eggNOG" id="KOG0926">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_0_4_1"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17982">
        <property type="entry name" value="DEXHc_DHX37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000637">
        <property type="entry name" value="ATP-dependent RNA helicase DHX37/DHR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF99">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="417"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="617"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="140"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="687"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="201"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="252"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="320"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1246" mass="138067" checksum="9CF66281ACAA88B9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ19</accession>
    <name>W6ZQ19_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_36538</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="KI963978">
        <property type="protein sequence ID" value="EUC45736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687724.1">
        <property type="nucleotide sequence ID" value="XM_007689534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ19"/>
    <dbReference type="STRING" id="930090.W6ZQ19"/>
    <dbReference type="GeneID" id="19123055"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36538"/>
    <dbReference type="eggNOG" id="ENOG502QRTW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_0_1_1"/>
    <dbReference type="OrthoDB" id="3238762at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF9">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 15" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12 15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887243" description="AA9 family lytic polysaccharide monooxygenase" evidence="16">
        <location>
            <begin position="20"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="17">
        <location>
            <begin position="291"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC45736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="327" mass="32727" checksum="2E3B5161C0895ACF" modified="2014-04-16" version="1">MKNTLLLTGISAFATHVAAHATFQDLWVNGSTCARLPNSNSPVTSVTSNDIRCNVNQGPASSKCSVPAGTTVTIEMHQQNGDRSCANEAIGGAHYGPVLVYLSKVSDASTADGSAPFFKIFQDTWAQNPSGGGGSDDYWGTKDLNKNCGKMDVKIPADLAAGDYLLRAEAIALHAAGSSGGAQFYMTCYQITVTGGGSSVPSGVSFPGAYKASDPGILINIYQKLASYVAPGPAVIAGGTEAVAGQAGSVVTATGGPPAATPTQTSTLRTSTVVTSAAPAPTNGGGSGGGCSVAKYGQCGGKGFTGCTTCASGSSCKASGEFYSQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRJ8</accession>
    <name>W6ZRJ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_82756</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683305.1">
        <property type="nucleotide sequence ID" value="XM_007685115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRJ8"/>
    <dbReference type="STRING" id="930090.W6ZRJ8"/>
    <dbReference type="GeneID" id="19126117"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82756"/>
    <dbReference type="eggNOG" id="KOG2214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009031_5_0_1"/>
    <dbReference type="OrthoDB" id="10049244at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07229">
        <property type="entry name" value="Pat_TGL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF44">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="7">
        <location>
            <begin position="160"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="572" mass="64288" checksum="C0B19D7CCC555FDB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRL9</accession>
    <name>W6ZRL9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_92938</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687120.1">
        <property type="nucleotide sequence ID" value="XM_007688930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRL9"/>
    <dbReference type="STRING" id="930090.W6ZRL9"/>
    <dbReference type="GeneID" id="19128175"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92938"/>
    <dbReference type="eggNOG" id="KOG0137">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_4_4_1"/>
    <dbReference type="OrthoDB" id="2588832at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF28">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="3"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="511" mass="57068" checksum="4ED2996841112279" modified="2014-04-16" version="1">MPHAALTRESVASHNKPDDLWCIIDHKVYDLSDFADAHPGGSVVLEQVAGQDATTAFYNLHRQEVLDKYSELCIGTIEGEKSEVLIQKPGELSPVPYAEPLWLRPQFKSPYFKESHRALQREIRKFVDTHITPEAQQKEKDGTYISQELIDKMAANDMLAMRLGPGKHLHGKKLMGVVKGEEFDYLHDLVQAQEGVRANARGFQDGNMAGMTISLTAVLQWMPESELKTRVVNEVLSGKKKMCLAITEAFAGSDVAGIRTTATKTADGKHYIVRGTKKWITNGMFSDYFVVGCRTDKGFSVLLVERDAAVETKLIKTSYSTTAGTAFVEFNDAKVPVENLLGEEHKGFIVIMSNFNHERFMMACAVIRQSRTVVEECLKWCNQRIVFGKKLIEQPAIRQKLAKMISHVEANQAWLESIAYQMTHMSYAQQSKLLGGPIGLLKSYATRSAHEIADEAVNIFGGRGLTQSGMGRVIEQFHRTYKFDAILGGTEEILGDLGVRQAMKNFPKSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSI5</accession>
    <name>W6ZSI5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_92327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="385"/>
            <end position="594"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="166"/>
        </location>
    </feature>
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        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
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        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="601" mass="67796" checksum="DBD869EC0F1AFFE1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTR9</accession>
    <name>W6ZTR9_COCMI</name>
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        <recommendedName>
            <fullName evidence="8">Ribosome biogenesis protein NSA2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_80802</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the pre-66S ribosomal particle.</text>
    </comment>
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        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.</text>
    </comment>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
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        <property type="project" value="EnsemblFungi"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 8" id="KW-0698">rRNA processing</keyword>
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        </location>
    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
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            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005424"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="261" mass="29897" checksum="84CE066D563E6CFE" modified="2014-04-16" version="1">MPQNEYIERFTKQHGKRFDHDERQRKKEAREGHNASKKAQNLRGLRAKQYAEKRRKEKIQMKQKIRAHEERNVKSNEAPEPATEALPSYLLDRSNEKNAKALSSAIKQKRNEKAARFSVPLPKVKGISEEEMFSVVKTGKKTKKKSWKRMITKPTFVGPGFTRRPVKYERFIRPMGLRYKKANVTHPELNVTVQLPIISVKKNPQQPLYTQLGVLTKGTIIEVNVSELGLVTAGGKVVWGRYAQITNNPENDGCLNAVLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZV03</accession>
    <name>W6ZV03_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_204</name>
    </gene>
    <organism evidence="2 3">
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007683886.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_204"/>
    <dbReference type="eggNOG" id="ENOG502R1AQ">
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="173" mass="17889" checksum="B56370233FA43EE8" modified="2014-04-16" version="1">MKSEAAEAFTSKTMRPEALEAAKALADQENRQPASTGSSGTEHSLPQDTPNNVPTTVTHSPSPSHDTVRSTHDTAGDASRASTLLSEVIQGAKTAVGDVLAWAEKKVGSLDSEKGGAGPYDSPATCMPSDLDAIASGILPAMPSKSQRDGGAMAKGKEIQDTISGKEKDKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVF8</accession>
    <name>W6ZVF8_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">RAVE subunit 2/Rogdi</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_89313</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685798.1">
        <property type="nucleotide sequence ID" value="XM_007687608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZVF8"/>
    <dbReference type="STRING" id="930090.W6ZVF8"/>
    <dbReference type="GeneID" id="19127451"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89313"/>
    <dbReference type="eggNOG" id="ENOG502S2HP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043442_0_0_1"/>
    <dbReference type="OrthoDB" id="66510at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028241">
        <property type="entry name" value="RAVE2/Rogdi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618">
        <property type="entry name" value="LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618:SF1">
        <property type="entry name" value="PROTEIN ROGDI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10259">
        <property type="entry name" value="Rogdi_lz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="32904" checksum="4840E9BE14ACC572" modified="2014-04-16" version="1">MSTAIWPPIDEDRLAHEQAASQARELEWLLVQLRETLQSLKAGLDECAALLAPSENGSTLVLTSVRSESLKGLITRIGTRITKGNIKLRLASLPPPKGSLTWDLVISSAPHAPTLVVPQLTSVRTSINSCLDAIDVATWGGDATNAQFVSGQLQLLHDHIIEAQAALKGHSPVQPSWWDNPVDENTFDPPLPANVSFHLFVFDAALVLEIRTLEPHHAGDTGSLTGFSIRNTFASALGGTRAPTHDEADRTFTYKNREVRVKEKIRVESQDPALISASAKLNALGHTVMLSRKALNIVMGRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZ31</accession>
    <name>W6ZZ31_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_85516</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684424.1">
        <property type="nucleotide sequence ID" value="XM_007686234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZ31"/>
    <dbReference type="GeneID" id="19126679"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85516"/>
    <dbReference type="eggNOG" id="ENOG502SJ4C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036113_0_0_1"/>
    <dbReference type="OrthoDB" id="4137815at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC49006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="487" mass="54330" checksum="06B250C38B36CA84" modified="2014-04-16" version="1">MGRPPATRACDRCHAVKEKCRRVSGQSACERCHRLQNTCQSLRPVGTAGRKPRHHRHEGSATTLQVRRARSASSSTVSAAASSINQGTTPASPASDIVSLPTSPARSDIVSTPRTLSMFADMNERELFIIKCISQGRPQIEQFLVAPSFRVNHHKTFARHLHNAPPWIHDALIATAALLACEYDPDPSPEDRAIGHRRAASAVSTLRSVRPLDSGDLPVILLLAVSALTFALHISGSGLAICRHALLTIKPIYDSTTVLDSECSAFFVCLILSETEECYLMGEVPTLRFKMEITDGSVDRYVGIAAPMLPCMYDICEVSYLLRQDERLSDSEITGIIDAIELVVHKWMPTLPEGCASRFLQQEMVSLLAQANIFRWAVLLMIHRLRYPFGTELAAGTALSQAILEELRSAVRHTKRSIPHMEIAYMVACFELTDLKERQMALEQIDIFIEFSRRSRIRLRDQLTAFWAIKDIRGQVHWCDAVSWLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1P3</accession>
    <name>W7A1P3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_83180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683577.1">
        <property type="nucleotide sequence ID" value="XM_007685387.1"/>
    </dbReference>
    <dbReference type="GeneID" id="19126204"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83180"/>
    <dbReference type="eggNOG" id="ENOG502SA9P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_245969_0_0_1"/>
    <dbReference type="OrthoDB" id="2107553at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.430">
        <property type="entry name" value="Galactose-binding lectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887322" evidence="2">
        <location>
            <begin position="19"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1571"/>
            <end position="1646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1646" mass="174620" checksum="0EA05CDDE4E5E228" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2Y3</accession>
    <name>W7A2Y3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT-NTPase and P-loop NTPases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_1080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683132.1">
        <property type="nucleotide sequence ID" value="XM_007684942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2Y3"/>
    <dbReference type="STRING" id="930090.W7A2Y3"/>
    <dbReference type="GeneID" id="19119164"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1080"/>
    <dbReference type="eggNOG" id="ENOG502SQZW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027897_0_0_1"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031352">
        <property type="entry name" value="SesA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17107">
        <property type="entry name" value="SesA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT-NTPase and P-loop NTPases N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="429" mass="48987" checksum="6553D8EB28CF52B3" modified="2014-04-16" version="1">MEALSGVASGMAVVSLSIQLIDSIDTIKTFVRKVKDAQQELERLVDLLERLEALLKDVHNLMKRQTSLQAEHFPIPSMTIFKCLESCEKTLEPLHTIIDKYAPATSKGGTRMEKLKTGLRFSLKAKDVKDFETRIERETVFLHASLGANCGAILMQLGPALLKNQNNSEATRPTHMEISIPDSESAIVSPKEDMTSLSTARTTRVSSSVIPVHWLLGRLGVHRRKIVRRVPENLDQRTSSYEYDHDSIVSEDYETTFLWSVLGYGLTWIQRRSFGVVLPSLNTFPLVHGFPNELYDTMNNGVNLEQFVSNQIANLGPEALLRAWPFDKRVVFQTLETGEWELGFEWALDEEACGYLLISEYQSLTIEDGDDDGPRSMEWPFCEREWGLFISEWNERKSKWCLRYERRRAAKARKQRARNGQKMPGAWVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3A2</accession>
    <name>W7A3A2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_32315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683039.1">
        <property type="nucleotide sequence ID" value="XM_007684849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3A2"/>
    <dbReference type="GeneID" id="19122073"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32315"/>
    <dbReference type="HOGENOM" id="CLU_2412945_0_0_1"/>
    <dbReference type="OrthoDB" id="10371661at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="92" mass="10552" checksum="769A94363DE2D0CB" modified="2014-04-16" version="1">MDSRAARHVQFPWYLDRSRTGCRKKNEQQQQKKKNKKWEVRGPSCPWRVVTFLFCGGHYTCVSVLVLGSTLRCSCSCSCATQCTPRSLPLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3H0</accession>
    <name>W7A3H0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cx9C motif-containing protein 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_32092</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CMC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682852.1">
        <property type="nucleotide sequence ID" value="XM_007684662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3H0"/>
    <dbReference type="STRING" id="930090.W7A3H0"/>
    <dbReference type="GeneID" id="19122025"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32092"/>
    <dbReference type="eggNOG" id="ENOG502S7M4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177210_0_0_1"/>
    <dbReference type="OrthoDB" id="13601at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1130:FF:000008">
        <property type="entry name" value="Cx9C motif-containing protein 4, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027179">
        <property type="entry name" value="CMC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15590">
        <property type="entry name" value="CX9C MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15590:SF0">
        <property type="entry name" value="CX9C MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08991">
        <property type="entry name" value="CMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="14"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR627179-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="80" mass="9263" checksum="BF61F3EFDA033FCC" modified="2014-04-16" version="1">MGEMERDLQTDPPCHPRACAIQNCIQRNNYNEEKCRKEVDALYECCNAFYERQGEKASTVSCPKYSLLKLKMQQRAKGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YM21</accession>
    <name>W6YM21_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_109284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964181">
        <property type="protein sequence ID" value="EUC40267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693228.1">
        <property type="nucleotide sequence ID" value="XM_007695038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YM21"/>
    <dbReference type="STRING" id="930090.W6YM21"/>
    <dbReference type="GeneID" id="19119401"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109284"/>
    <dbReference type="eggNOG" id="ENOG502SWE6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1906384_0_0_1"/>
    <dbReference type="OrthoDB" id="3680350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886528" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="13868" checksum="CA96ADAE59D772C4" modified="2014-04-16" version="1">MHFLYLFAAVTATASASFTNKCQSCSLIINKAEAGVMGCDCFNDANQLVGSILRLSTCFANADGKLIPQANGNFVKSCSVEGLFPSSQRSLFLSVKCKDNSGNTQSGSFDINAGSTITSVNGVMKCFGQGGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMD0</accession>
    <name>W6YMD0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcium-dependent phosphotriesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_108852</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964166">
        <property type="protein sequence ID" value="EUC40427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693045.1">
        <property type="nucleotide sequence ID" value="XM_007694855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMD0"/>
    <dbReference type="GeneID" id="19119322"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108852"/>
    <dbReference type="eggNOG" id="ENOG502RYG9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033924_3_1_1"/>
    <dbReference type="OrthoDB" id="5307922at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051288">
        <property type="entry name" value="Serum_paraoxonase/arylesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799">
        <property type="entry name" value="PARAOXONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799:SF20">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="49259" checksum="221838DE3918DE89" modified="2014-04-16" version="1">MSKAVLLALVVAWGASFYQIYLKDLLVTTFGVGRVMQDIDEFPYSCRRVEHPRLEACEDIWLDDKGRTLYAACAGTSGRMAWNQAMNQVNVTGRRPGGSELIALDIDNPGADGLFNLRSIKPTGNYIGATGNTDLDLLGFDALILDDDTIQFYFVNQRPPVGPSNDIIDAFKTGDNSTIEVFEMKKGQETMRHVRTVFSSEIWTPNRVAALGDGSGAFLVTNDHSVKLGLRREFDYFIGGGNIAYCPGTGPCHPAYSGNEVDESTLKTTAASDSPPYMPYLKRFLSFIIPRPHLKFPNGLTRGTDNLFYIPSAIDGQVRVFALDPQNNYTLRLLEIINVGMPLDNISPDAKGDLYVAGFPSLAQTGKSFSDPYNEISPVTIWRIRKIGSEEGKESAEYRVEKVIEDKESKVLSGSTTVRHDVKTGRLFVSAAVHPYLVVCEPRASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMN1</accession>
    <name>W6YMN1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="4">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_9596</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16 17">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the TOP6A family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="4"/>
    <dbReference type="EMBL" id="KI964156">
        <property type="protein sequence ID" value="EUC40547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692932.1">
        <property type="nucleotide sequence ID" value="XM_007694742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMN1"/>
    <dbReference type="STRING" id="930090.W6YMN1"/>
    <dbReference type="GeneID" id="19128756"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9596"/>
    <dbReference type="eggNOG" id="KOG2795">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037229_0_0_1"/>
    <dbReference type="OrthoDB" id="5377392at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000706">
        <property type="term" value="P:meiotic DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1360.10:FF:000018">
        <property type="entry name" value="Type II DNA topoisomerase VI subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848:SF0">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21180">
        <property type="entry name" value="TOP6A-Spo11_Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="DNA topoisomerase IV, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52041">
        <property type="entry name" value="TOPO_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Spo11/DNA topoisomerase VI subunit A N-terminal" evidence="12">
        <location>
            <begin position="159"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="13">
        <location>
            <begin position="268"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC40547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="483" mass="54495" checksum="0CC01E918A03780D" modified="2014-04-16" version="1">MDEDDFEDLLFGDPGTPMCPSDMLLDESNDDILFSNRHAQFHDWESADTISSPTVPGVLSGEHTPTNSETNVYEQHGRHTAEPTQRPVRDRYWVIARIEAMLERIVDNLLEQHKSLTITLKSRANFSRRNAPSNEGDGSIPKPKERDINFPGANAQEAWKFTVLLRILELIHGSLLDNTMMTKRDIYYRHPDLFVKQSVVDRYVDDLACTFGITRSQLNVTAAAKGLVAGNFKLEQANNLFHRMSSSEGLLIPVVRDNDSWDLTETQWVLIIEKEATFRSLIGSAQWSMLGLHGVVVTAKGYPDVASRQFLRQLGNTAPHIPMFVLVDLDPDGIAILSTYKYGSYRLMHEDVALMNTPALSLPNIQWLGVKRDNMSLSLVGEDGAERKMIHQPQGLMRLTMRDRTKAIRTLEWDLCGEDGLERGWRQELQWMLMLNIKAEMQVLDELPGGLVSWLSDQLGHANNLLVTATKTGSDCSDDGMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNF6</accession>
    <name>W6YNF6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_107681</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964134">
        <property type="protein sequence ID" value="EUC40872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692621.1">
        <property type="nucleotide sequence ID" value="XM_007694431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNF6"/>
    <dbReference type="STRING" id="930090.W6YNF6"/>
    <dbReference type="GeneID" id="19119096"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107681"/>
    <dbReference type="eggNOG" id="ENOG502QPY2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011075_0_0_1"/>
    <dbReference type="OrthoDB" id="3886144at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF47">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="67"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="729" mass="80898" checksum="FD82B39C9F60B836" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNF9</accession>
    <name>W6YNF9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_77455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964133">
        <property type="protein sequence ID" value="EUC40877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692593.1">
        <property type="nucleotide sequence ID" value="XM_007694403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNF9"/>
    <dbReference type="STRING" id="930090.W6YNF9"/>
    <dbReference type="GeneID" id="19125376"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_77455"/>
    <dbReference type="HOGENOM" id="CLU_013929_17_3_1"/>
    <dbReference type="OrthoDB" id="3693029at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9270" checksum="ED998F7D90E3F2D5" modified="2014-04-16" version="1" fragment="single">MSNIEAALAAIDALGPGESFTYTEIAKRYGVVRSTLTRRHQGRCASPTTGCQKRQLLHPQQEQALIAYINRLTDRGLPPTQSMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPT1</accession>
    <name>W6YPT1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_111309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964351">
        <property type="protein sequence ID" value="EUC39533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693949.1">
        <property type="nucleotide sequence ID" value="XM_007695759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPT1"/>
    <dbReference type="GeneID" id="19119750"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111309"/>
    <dbReference type="HOGENOM" id="CLU_198479_0_0_1"/>
    <dbReference type="OrthoDB" id="10373203at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="77" mass="8532" checksum="6F14AF64D5986DDE" modified="2014-04-16" version="1" fragment="single">DIVGIGHVMCHHAKAVPSVMAGLLCDGNHQEWRQTSVMSGRKSDGRTGSNEDIRIGEYHYLLSSWSTQTVLSYQLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPT7</accession>
    <name>W6YPT7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ent-kaurene synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_106270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964105">
        <property type="protein sequence ID" value="EUC41382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692089.1">
        <property type="nucleotide sequence ID" value="XM_007693899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPT7"/>
    <dbReference type="STRING" id="930090.W6YPT7"/>
    <dbReference type="GeneID" id="19118829"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106270"/>
    <dbReference type="eggNOG" id="ENOG502QUXU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005861_0_0_1"/>
    <dbReference type="OrthoDB" id="2343925at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010333">
        <property type="term" value="F:terpene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016102">
        <property type="term" value="P:diterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017057">
        <property type="entry name" value="Ent-kaurene_synthase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050148">
        <property type="entry name" value="Terpene_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31739:SF25">
        <property type="entry name" value="(E,E)-GERANYLLINALOOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31739">
        <property type="entry name" value="ENT-COPALYL DIPHOSPHATE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036498">
        <property type="entry name" value="Ent-kaurene_synthase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="920" mass="102482" checksum="179D3120CB3EDF26" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPX4</accession>
    <name>W6YPX4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_8838</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI964102">
        <property type="protein sequence ID" value="EUC41442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692022.1">
        <property type="nucleotide sequence ID" value="XM_007693832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPX4"/>
    <dbReference type="STRING" id="930090.W6YPX4"/>
    <dbReference type="GeneID" id="19127250"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8838"/>
    <dbReference type="eggNOG" id="ENOG502SJMQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046574_1_0_1"/>
    <dbReference type="OrthoDB" id="93019at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051178">
        <property type="entry name" value="TfdA_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779:SF2">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT XANTHINE DIOXYGENASE XAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779">
        <property type="entry name" value="DIOXYGENASE RV0097-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="394" mass="45419" checksum="A16BFFDA485080C6" modified="2014-04-16" version="1">MASNFKIEPLVHPEGKTCKFGAVITGLDLNNFTEEIVAQLEKAIWEHKLLIIKGQHDLKPKRSWELLRALDPEMIIEDDDDMINLFHPHQWFRDSFQAIKVPDAGLFYFIGKGPQDDPRYGKPGLDMGNASLSHYYSIPLSDEDFEAGRTRFHVWYMNGFYWRHGISKCTILRPIKFPTEGLDKQTVEWADGSGTTMEVRPGRQAFLDVEQLYDMLSDEEKRMADHSWADYNYFPFENLKDCHYAPNGLGVVTEGREQPDEELLKLGGASKDWQKRYPLVWVNPVTGKKSFQCMHHLVRRLYIRDGPDETPKIIDDLGEVRKFLDKIQSRIIKPENIWVGPEEEHDLVLFGSYGLLHSNIDYPASWGKRSIHQAFMPTSKAPMGPVPIPDISKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQD0</accession>
    <name>W6YQD0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_40192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964092">
        <property type="protein sequence ID" value="EUC41652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691821.1">
        <property type="nucleotide sequence ID" value="XM_007693631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQD0"/>
    <dbReference type="STRING" id="930090.W6YQD0"/>
    <dbReference type="GeneID" id="19123833"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40192"/>
    <dbReference type="eggNOG" id="ENOG502S4TA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078549_0_1_1"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12467">
        <property type="entry name" value="RRM_Srp1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000123">
        <property type="entry name" value="Pre-mRNA splicing factor (Srp1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034403">
        <property type="entry name" value="Srp1p_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050907">
        <property type="entry name" value="SRSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23147">
        <property type="entry name" value="SERINE/ARGININE RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="7"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="224" mass="26212" checksum="217026911BE981D0" modified="2014-04-16" version="1">MSRGGGTTLYVTGFGHGTRARDLAYEFERYGRLVRCDIPAPRSASSRLSFAFVEYESRRDADDAYHEMHNKRIGRDDLLKIEWARTPPSASWRFDSGRDRPRGERSERGGDRGDRSDRGDRADRGVRSPRRRSTSPRRERGASPRKDDRRERDYDRRDRDRSRSPIDGDREMKDVRDREDDRGDRDRGDREERRDREREAEPPAEPRKIESPPPAAHDDLDVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQI4</accession>
    <name>W6YQI4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_105536</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964091">
        <property type="protein sequence ID" value="EUC41672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691807.1">
        <property type="nucleotide sequence ID" value="XM_007693617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQI4"/>
    <dbReference type="STRING" id="930090.W6YQI4"/>
    <dbReference type="GeneID" id="19118701"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105536"/>
    <dbReference type="eggNOG" id="KOG3022">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024839_0_1_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904564">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly scaffold complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001300">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor CFD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03039">
        <property type="entry name" value="NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028600">
        <property type="entry name" value="NUBP2/Cfd1_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF19">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="15"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC41672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="324" mass="34696" checksum="FC1B34D2C7FC7A4E" modified="2014-04-16" version="1">MPLDNIRNILLVLSGKGGVGKSSITTQLALTLSLQGHSVGVLDIDLTGPSIPRFFGIEDSKVRQAPGGWIPVDVHGAQTLPGKKLKDEEGESAQDQKIGPLSCMSLGFILASRSDAVIWRGPKKTAMVRQFLTDVLWPPLDYLLIDTPPGTSDEHISLLETLLKNTTPSPSLNPNLPFLAGAVVVTTPQAISISDVKKELNFCKKTGIRVLGVVENMAGFVCPNCSECTNVFSKGGGQVMANDFQVPFLGSVPIDPAFVELIESGTRPVYPQGTVMQGKDVSTEDVAKARNSEGSLVDKYRDCSLYPLFDGFVTRLKADVAGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRY0</accession>
    <name>W6YRY0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_39695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964069">
        <property type="protein sequence ID" value="EUC42202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691265.1">
        <property type="nucleotide sequence ID" value="XM_007693075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRY0"/>
    <dbReference type="STRING" id="930090.W6YRY0"/>
    <dbReference type="GeneID" id="19123736"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39695"/>
    <dbReference type="eggNOG" id="KOG0179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_1_0_1"/>
    <dbReference type="OrthoDB" id="268479at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03757">
        <property type="entry name" value="proteasome_beta_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000027">
        <property type="entry name" value="Proteasome subunit beta type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="28739" checksum="16701F9A92FB3810" modified="2014-04-16" version="1">MAALYTGAPPQGGPGYSFKQTPTTVPSGERQHGFYPYTDNGGSTLGISGADFAILAGDTRSTSGYNINTRYAPKLFKIGGEGSDNKGARIVLSVVGFAADAHALKERLDTIVKMYKYQHGKPMTVSACAQRLSHILYNKRFFPYYVHAILGGLDEDGKGALYSYDPVGSYEREQCRAAGAAASLIMPFLDNQVNFKNMYEPGSGVGHELKSKQAEPLPRDHVEDLVRDAFTSAVERHIEVGDGLQMMIITKEGIAETYTPLKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS35</accession>
    <name>W6YS35_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_109129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964176">
        <property type="protein sequence ID" value="EUC40318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693169.1">
        <property type="nucleotide sequence ID" value="XM_007694979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS35"/>
    <dbReference type="STRING" id="930090.W6YS35"/>
    <dbReference type="GeneID" id="19119373"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109129"/>
    <dbReference type="eggNOG" id="ENOG502SJ8C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059226_1_0_1"/>
    <dbReference type="OrthoDB" id="25129at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="363" mass="40200" checksum="D6633AACAD132CE3" modified="2014-04-16" version="1">MASPYDFTTEQGLGDYLSAAQSGHTSVKLLSGGTANYVYRCTKQDESTSIFKHAAPYLHSNKNFAFDPTRMDYEANILTQLASKSKPFFANPPNTTAHAVQLLNYNKDNKLLEIEDGGTCNLKDAYTSPDLNIPQIGQHLATWLAALHNSSTKTSLVLKGQDSSSKNNPIGVAVYRHSYHNLHLALEKYGYDTHLAYRINEDFGSLLATDDECVCHGDFWPGNVLVRSNEAQPPSLTIVDWEMVRRGTSATDVGQFAAEAFLLDRFRGGRGLLAAFLKAYVAERKDGEVLGEMWLKRMVVHWAVHVAFWPTRVEWTDAAGTQKLVDIGVGALEGMLKDDWEKVLGSPLLEDVGDVFAPILERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSL0</accession>
    <name>W6YSL0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_9534</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964151">
        <property type="protein sequence ID" value="EUC40610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692860.1">
        <property type="nucleotide sequence ID" value="XM_007694670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSL0"/>
    <dbReference type="GeneID" id="19128637"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9534"/>
    <dbReference type="HOGENOM" id="CLU_1731288_0_0_1"/>
    <dbReference type="OrthoDB" id="3932980at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889191" description="CFEM domain-containing protein" evidence="9">
        <location>
            <begin position="19"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="10">
        <location>
            <begin position="48"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="151" mass="16601" checksum="706ECDB17683E5D5" modified="2014-04-16" version="1">MHFTSIATLFSVLAVANAQLTFNITRASAPGNMAKYHCLNNNKLKGWLPSCIYECQIQASMLDGCAAEDFACHCVNHYKYSKLIEPCTVPPGLGGKGHCTVNDLYKARPIIDDMCNFYNATIYKSYDGCPQMLSPSVTYGIIMNEGVVITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSY1</accession>
    <name>W6YSY1_COCMI</name>
    <protein>
        <submittedName>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964123">
        <property type="protein sequence ID" value="EUC41043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692444.1">
        <property type="nucleotide sequence ID" value="XM_007694254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU41"/>
    <dbReference type="STRING" id="930090.W6YU41"/>
    <dbReference type="GeneID" id="19119004"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107207"/>
    <dbReference type="eggNOG" id="KOG4600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062495_1_0_1"/>
    <dbReference type="OrthoDB" id="1867012at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000042">
        <property type="entry name" value="50S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_bL27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="262" mass="28725" checksum="C7D33D4A93EA966D" modified="2014-04-16" version="1">MLLPRIFAPVRASIATSAAFIAPSTRVLDALRVANGSATPTPVLSFVRHSAHQAQGRANGAKDGPGKRLGAKKSGGEYVIPGNIIFRQRGTSWFPGENCKFGRDHCIFATESGYVRYYRDPRLHPKRQYIGVALEKDHTLPYPPNAARRRRLNFTPVPVASPPPASESAPVAAAVAGAEAPREATKKELSLRSGKGYAYREANWVIGRAAERAGVQVKEFVPGDRWTAWRKRSLRIQANVERKRLRSAGKKVAKPKARKARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV23</accession>
    <name>W6YV23_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_106290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964105">
        <property type="protein sequence ID" value="EUC41390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692092.1">
        <property type="nucleotide sequence ID" value="XM_007693902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV23"/>
    <dbReference type="GeneID" id="19118833"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106290"/>
    <dbReference type="HOGENOM" id="CLU_1506897_0_0_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="179" mass="18646" checksum="00D0414CD6850424" modified="2014-04-16" version="1" fragment="single">MTITTWGWNRNPLGGTKTSNGGNGNGGQGSPTTTRPNLPGAPTLTTLEPPYSGSECSSYLHTTRCNGSGGKSACVTQDLCVPTRPCYSTYSATGTPSCSGEYSICLSTTVIARCAQADFLAAPADATAPPSLIDDKFIAVAPSVPTPEPSLRLEEDTYRQKEPADDEPGEQEVSVPKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVI6</accession>
    <name>W6YVI6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_31310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964364">
        <property type="protein sequence ID" value="EUC39519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693961.1">
        <property type="nucleotide sequence ID" value="XM_007695771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVI6"/>
    <dbReference type="STRING" id="930090.W6YVI6"/>
    <dbReference type="GeneID" id="19121838"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31310"/>
    <dbReference type="eggNOG" id="ENOG502SUZ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_3_5_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055530">
        <property type="entry name" value="DUF7104"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF78">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23397">
        <property type="entry name" value="DUF7104"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="46"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="431"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="458" mass="52225" checksum="89DF89979DE71330" modified="2014-04-16" version="1" fragment="single">MDILIYEPIDLDRPAFRLLQLLRGKGPTIECMLYQAYLDGTDTVPYDALSYTWGGTDKTSTVIVNGKTFDVTKNLHSALQHLRSEDIDRVLWVDAICIDQDNERERGHQVQQMCKIYSQAEEVIVWLGQATEETNILMDSLRRLDGYSLMHGHRHWDLAQWTTFWLLDLRDPGFEPHKGLDLLLRRSWFRRVWILQEIANAKKASVWCGTKSVRAHTFALAPSLIGIKPERHCQAVLDIMPGRLREESWWSENRDLYNLLLKFSESEASDPRDKVYALLGISSDAWNANSLRPDYTKGLQEVIRDTSLFLFGPSDVSYETMPELLEDLTSRNATSFLEVVRTSDIKGVEHFLVRRGLEVPLSEDMIKGAVRNEKSGRDIMRLFLQERRGEVKVTEAVVKAAVKNVRNGRDIITLLLQQCDDEVQMTKVVINALQAASAGGHKAVVKLLLDKGAKTNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVY8</accession>
    <name>W6YVY8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_7015</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964025">
        <property type="protein sequence ID" value="EUC43582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689897.1">
        <property type="nucleotide sequence ID" value="XM_007691707.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6YVY8"/>
    <dbReference type="GeneID" id="19125150"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7015"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_1_0_1"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08956">
        <property type="entry name" value="KR_3_FAS_SDR_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000012">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000019">
        <property type="entry name" value="Polyketide synthase type I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF51">
        <property type="entry name" value="INACTIVE PHENOLPHTHIOCEROL SYNTHESIS POLYKETIDE SYNTHASE TYPE I PKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="555"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="648"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2059"/>
            <end position="2134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC43582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2542" mass="276183" checksum="DC09887D19380BF0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVZ0</accession>
    <name>W6YVZ0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964090">
        <property type="protein sequence ID" value="EUC41695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691779.1">
        <property type="nucleotide sequence ID" value="XM_007693589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVZ0"/>
    <dbReference type="GeneID" id="19123823"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40153"/>
    <dbReference type="eggNOG" id="ENOG502T1F7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100635_0_1_1"/>
    <dbReference type="OrthoDB" id="5230873at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886314" evidence="1">
        <location>
            <begin position="20"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="181" mass="19344" checksum="154F6B544D75A365" modified="2014-04-16" version="1">MSALKSFALLSTLPFLALGATRRAAARNFIFYGYSDQFGGSPLIYSDGYAYVGSIDATNTTDAAIVNFTSTTNNEWLGSPNVTVPGHTSSWSNATFFIPTADDSDKRVGFLTSNSTIDGKAISGFRLYGSMAAFVTDDGQLVSAWTGLQVSQNLHRLYWNDTSLGQIPVTLTTVAPSNPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWY9</accession>
    <name>W6YWY9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_10000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964205">
        <property type="protein sequence ID" value="EUC40039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWY9"/>
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    <dbReference type="GeneID" id="19117583"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10000"/>
    <dbReference type="eggNOG" id="ENOG502RHGF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033245_0_0_1"/>
    <dbReference type="OrthoDB" id="3883941at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="361"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="410" mass="45116" checksum="459A7544D2DBF6DC" modified="2014-04-16" version="1">MFSRQATQNARFAARCARRPAARVANPQYCAQHPRFQSTQTATSGNSGVGTHAAVGAVSGALAAVTVGYIFYRQSGARDVVVASKTAKGYVKSASQKIKEQTPEPNEALQWLRQAAQSYAAFIPGAKSYVDSAFDDLDAIRAKHGDEVDRIVREAYDEMRQVLGKGDMSLVTAHQTWDVITKHMSRIADLAGDASQQIMDNHPQLKEKLGGNIDKLKEYGDKYGPEAKKEVDRTWNQISDVVKTGMSAGNIEKIRSIVQEKIEKLNKMGDEVWKKGMEQAKPYLDKNPQVKKLVEENADALKGGNVQELYQRVKSAVEKGDTGDLQSYIKSVADKAKDGGFGDYEQYLKKIPGGDQILPKLSQLQEVAQKHGDEAQKLLKEAVSEIADILQKKGDEASKLAEKAKEDSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXZ7</accession>
    <name>W6YXZ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nonribosomal peptide synthetase 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Extracellular siderophore synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_98843</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964009">
        <property type="protein sequence ID" value="EUC44207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689287.1">
        <property type="nucleotide sequence ID" value="XM_007691097.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6YXZ7"/>
    <dbReference type="GeneID" id="19129343"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98843"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_60_0_1"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19542">
        <property type="entry name" value="CT_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19531">
        <property type="entry name" value="LCL_NRPS-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000084">
        <property type="entry name" value="Enniatin synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000015">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.30:FF:000003">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000014">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003417">
        <property type="entry name" value="PRK04813.1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Carrier" evidence="12">
        <location>
            <begin position="570"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="12">
        <location>
            <begin position="2066"/>
            <end position="2139"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="12">
        <location>
            <begin position="3137"/>
            <end position="3213"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="12">
        <location>
            <begin position="4641"/>
            <end position="4720"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="2058"/>
            <end position="2085"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00073487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00083595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC44207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="5158" mass="574560" checksum="6267D66E6481718C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYF1</accession>
    <name>W6YYF1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964055">
        <property type="protein sequence ID" value="EUC42600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690868.1">
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    <dbReference type="OrthoDB" id="3660116at2759"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="78" mass="9008" checksum="50248D66B1140E1B" modified="2014-04-16" version="1">MEKVESCLDPETRTADDCRKKLTSQSQSRQPQMCIRAPKHQNMMLQNASRPAPRTPCTCSQPMNHDKEKFLCWTEQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYI5</accession>
    <name>W6YYI5_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690846.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYI5"/>
    <dbReference type="GeneID" id="19118205"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103011"/>
    <dbReference type="HOGENOM" id="CLU_1895833_0_0_1"/>
    <dbReference type="OrthoDB" id="3681772at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="130" mass="14614" checksum="23270BE0ECF593BF" modified="2014-04-16" version="1">MADKPMYVRYSHPAMRHPRPTRRLPTVMFNSFEAQGEQGSPLGLFLQLQEEMDREGPWGLRPVFLPTSYANSNAPLTAINQQGIGGYLRKKAIVANAQVFSRARGQSTYFAELAMLEAGLSRLTLEDNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z039</accession>
    <name>W6Z039_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_40654</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z039"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_40654"/>
    <dbReference type="eggNOG" id="KOG2319">
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    </dbReference>
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    <dbReference type="OrthoDB" id="3660009at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24188">
        <property type="entry name" value="ANKYRIN REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24188:SF29">
        <property type="entry name" value="GH09064P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="213"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="566" mass="64896" checksum="1BCAA4DE2E16B249" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0J2</accession>
    <name>W6Z0J2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_100782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964028">
        <property type="protein sequence ID" value="EUC43480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690030.1">
        <property type="nucleotide sequence ID" value="XM_007691840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0J2"/>
    <dbReference type="GeneID" id="19117745"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100782"/>
    <dbReference type="HOGENOM" id="CLU_061853_0_0_1"/>
    <dbReference type="OrthoDB" id="3770722at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="283" mass="31660" checksum="626B7C0E3521B35C" modified="2014-04-16" version="1">MNPTNSNTNNLEHLLYGNDAPTVTPSTPTQPRPIRPITTIMPVLDRTIYNEAEETEGSERTLEYVRVQLQALRYLECYPSDTLSGHQACEWTQMISPSNFKPTAQEALRLCYYLRSKDFNTYAKVKRGYMNLYVADQESDMRGPHVDVLYWKQDVGTNEIRYQCSPRTPGPVVVVGGGGGGGGGGGGGGRRNAIATTLSLHSAEGRSLYIHFYSSHDEQRMIERQMAGPRRGEDRRTLNSLTTLAAAAEIRLQNLVNLENPDLGEIEVTLMQLEEYRALMRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z142</accession>
    <name>W6Z142_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_38672</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964030">
        <property type="protein sequence ID" value="EUC43413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690078.1">
        <property type="nucleotide sequence ID" value="XM_007691888.1"/>
    </dbReference>
    <dbReference type="GeneID" id="19123517"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38672"/>
    <dbReference type="eggNOG" id="ENOG502QU61">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003548_0_0_1"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001995">
        <property type="entry name" value="Peptidase_A2_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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            <begin position="573"/>
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        </location>
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            <end position="950"/>
        </location>
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        <location>
            <begin position="1485"/>
            <end position="1517"/>
        </location>
    </feature>
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        <location>
            <begin position="600"/>
            <end position="652"/>
        </location>
    </feature>
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        <location>
            <begin position="1167"/>
            <end position="1192"/>
        </location>
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            <end position="622"/>
        </location>
    </feature>
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        <location>
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            <end position="652"/>
        </location>
    </feature>
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        <location>
            <begin position="1179"/>
            <end position="1192"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50175"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1783" mass="201440" checksum="B1F81FC48DF58208" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6Z1E9</accession>
    <name>W6Z1E9_COCMI</name>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="362" mass="39634" checksum="6629407808EF5829" modified="2014-04-16" version="1">MTMVENMGPTWSRCYVAVSERDKPVAPFIKPGSFHDGVVVPIGFQFPLPAFSSVFAYTLIGSEKGEVFWVSMMMPRKPKSKGYRFPGPWDRFLRIVSLGKGTGHRSRTVHCLSVSRKDTSCPEKPPQHLHGVVDLQVRCDLHCMCTPRQSPRNFAGERKGIREGVDAKLSVGRRVETVETARVGQDEMSCLRQQDGLMPSIASVMVRRRTKSVCPARPWTHRMDSARPPNEATDKGLGCKGARDLVQDEDQGRAEGVARRAAAAATAAAAATAAAAAATAAAAAATRCIDVGREWDTELRRITQNALVLTWLARVEPAKSRVVAMHACPSTQTSRPVSFATHDRGLPWRLINRKHLAQGEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1M5</accession>
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        <recommendedName>
            <fullName evidence="4">DUF1770-domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="2" type="ORF">COCMIDRAFT_95052</name>
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    <organism evidence="2 3">
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502SAKD">
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140580">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20768" checksum="C6668D989DD6D6E4" modified="2014-04-16" version="1">MDSDAPIEVGSVLQGASINRNPSPRHDVNPSTAASKKQPVRLNEHPDPDVSDVGEDEIPLSVLDPVPRNKTMPPLPDLRFEQSYLKSIEHAEGWKGVLWITLRDQVIMCFAQGVLWTLLLNGWRHWNRSTKFSGQGVGARIRRWWWGVNNWSIPTTKSRLKDPKLARNVSEYYKGEFSNAAQD</sequence>
</entry>
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    <accession>W6Z328</accession>
    <name>W6Z328_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_99031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC44123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691194.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19129383"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99031"/>
    <dbReference type="eggNOG" id="ENOG502S69U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="3210850at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887120" description="G-protein coupled receptors family 1 profile domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="37326" checksum="E86BCDE32E73F309" modified="2014-04-16" version="1">MRHFLALNTIWAVSTAYVTPVPTTTHDGLDFVRQASFKYSDPVKLRISLVVTSKICLGLLAGLLGYRIRQFNQHLLKNMTLTHVYIFIDYISAMTFITAAAIVHNGLGITTDKICRAAIRLCLLFYTAGKVSMYLFLVERIHVLRAPYRSRWSDYLWIFSTIGICVSLGAIGVAGFAVPITSLSKADGRCRIGLQPYAIIPLLVCDIVINVLLTLVFIYLLSPVVRGNRPSGAGFASRLARVIGTLCGRAKQRTAVNLHPANQLLVRRVEKLLFKTLVGCLLVVLPASANLTALCIYRGKMPAFMCFTICIFDVTWAAVVLHWLTMASADRRESGAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3E7</accession>
    <name>W6Z3E7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_36104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687217.1">
        <property type="nucleotide sequence ID" value="XM_007689027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3E7"/>
    <dbReference type="GeneID" id="19122938"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36104"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_1_1"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="107"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="551" mass="60475" checksum="1078173D8142E79A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3L4</accession>
    <name>W6Z3L4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_104120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964069">
        <property type="protein sequence ID" value="EUC42204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691273.1">
        <property type="nucleotide sequence ID" value="XM_007693083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3L4"/>
    <dbReference type="STRING" id="930090.W6Z3L4"/>
    <dbReference type="GeneID" id="19118444"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104120"/>
    <dbReference type="eggNOG" id="KOG0177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_12_0_1"/>
    <dbReference type="OrthoDB" id="268428at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061133">
        <property type="term" value="F:endopeptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03758">
        <property type="entry name" value="proteasome_beta_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000008">
        <property type="entry name" value="Proteasome subunit beta type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035206">
        <property type="entry name" value="Proteasome_beta2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="203" mass="22656" checksum="5CEFCDF3586381FC" modified="2014-04-16" version="1">MEVLLGITGKDFTLIAASKAAMRGATILKASDDKTRELNKHTLMAFSGEAGDTVQFAEFIQANVQLYSMRNNMELSPAATANFVRGELASALRSRKPYTVNLLLGGYDTIADKPTLYWIDYLASQAALPYAAHGYAQYYCLSLLDKHHHPDIDYEQGLKIMRMCTEELKRRLPVDFKGVMVKAITKDGIKDVEFEDDVKVVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3P2</accession>
    <name>W6Z3P2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein transport protein SEC13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Protein transport protein sec13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_37574</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688880.1">
        <property type="nucleotide sequence ID" value="XM_007690690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3P2"/>
    <dbReference type="STRING" id="930090.W6Z3P2"/>
    <dbReference type="GeneID" id="19123274"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37574"/>
    <dbReference type="eggNOG" id="KOG1332">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032441_0_1_1"/>
    <dbReference type="OrthoDB" id="364224at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of protein exit from endoplasmic reticulum"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of TORC1 signaling"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032527">
        <property type="term" value="P:protein exit from endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000017">
        <property type="entry name" value="SEC13 homolog (S. cerevisiae)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF2">
        <property type="entry name" value="PROTEIN SEC13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
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        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="6 13" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="51"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="204"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013473"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC44580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="298" mass="32604" checksum="789451B3C0BAC9A4" modified="2014-04-16" version="1">MANVIANSGHDDMIHDAVLDYYGRRLATCSSDKTIKIFEVEGDKHTLVETLRGHEGAVWSVAWAHPKYGNILASSSYDGKVLIWREQSNSWQKIYEVALHTASVNLVAWAPHEAGCLLACASTDGNVSVLEFKDNNWTHQLFQAHGSGVNSVSWAPAIAPGQAVSAGGNQVAARRLVTGGSDCQVKIWEFSPDSGSWQNLQILPGGHLDWVRDVAWSPTVLSKSYIASASQDKTVVIWTSSDLRGEWKRTKLDVDAAAWRVSWSLSGNALAVSTGDNRVSLWKERLSGGWECVKTIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3Z2</accession>
    <name>W6Z3Z2_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_92843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC46477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688884.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_92843"/>
    <dbReference type="eggNOG" id="ENOG502SZYQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143025_0_0_1"/>
    <dbReference type="OrthoDB" id="4476188at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="46"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="155" mass="17039" checksum="E75631AE5A9D73FC" modified="2014-04-16" version="1">MSDYTGPGIYTISPFHAPEMELDIWKGETKEGTQVKLYKKASTSSNHQFQIVYAGGVGGHPEKGDREYFIIPVNSGLYVTAHETEKVVTTQLLPPRDASIRWKLAHAGNGAYYINHVDGKKQLNVRGAGKADGTEVITYKIETSPNSQFILRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z403</accession>
    <name>W6Z403_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_53779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686978.1">
        <property type="nucleotide sequence ID" value="XM_007688788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z403"/>
    <dbReference type="GeneID" id="19124594"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_53779"/>
    <dbReference type="HOGENOM" id="CLU_1708472_0_0_1"/>
    <dbReference type="OrthoDB" id="3940153at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="154" mass="16926" checksum="8929B09B92D16A1A" modified="2014-04-16" version="1" fragment="single">MSRRTRTIYDQRYDSATVLPLPPEEGALYPSAIHDSHLYGEVISPTARHSASESSYVTEVDECTPSYLHCMPMSTHEYPSQHYHTDVVAPTLRPSLPPPVNSSSTSSPSSVAPTISISTVIDGNTLGCSQCGVEFTGRYRRGNLARHARHKHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4L8</accession>
    <name>W6Z4L8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_92153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686776.1">
        <property type="nucleotide sequence ID" value="XM_007688586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4L8"/>
    <dbReference type="GeneID" id="19128022"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92153"/>
    <dbReference type="eggNOG" id="ENOG502QZN7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062681_0_0_1"/>
    <dbReference type="OrthoDB" id="5420410at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031349">
        <property type="entry name" value="Tfb6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37781:SF1">
        <property type="entry name" value="ADR380WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37781">
        <property type="entry name" value="TFIIH COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17110">
        <property type="entry name" value="TFB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="302" mass="33094" checksum="A62D8E1F83AF8352" modified="2014-04-16" version="1">MATARSPASDPFAENLPTPPASSAAPSQHPSPLPQPRKHPLKPGGPRESDLIRYLDHGINSIQKRVDNRMTNRKRKPEPGEEQGYSAFWEVARDLDGLVDVVWVSASPNLQIPYLLNIAVLTAEFLPLFTSTTRSTQATFRLVSKLDYAFSSLLTGHDLATGELLPGFENGRTVTTTDKVRLKGIVDRTRLTVVRVMSGESVVGDDQDVGEAMDTDNEREAEPRGHDGIVTFEGFENNTDDEEEDDEWEERGIATIYEKTIGELGDVLGGPPIGIITDDWASKGAEQQKSGGGFVESEIDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z510</accession>
    <name>W6Z510_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_35570</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686635.1">
        <property type="nucleotide sequence ID" value="XM_007688445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z510"/>
    <dbReference type="GeneID" id="19122815"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35570"/>
    <dbReference type="eggNOG" id="ENOG502SHVM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_7_1"/>
    <dbReference type="OrthoDB" id="5331848at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="37"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="375" mass="40946" checksum="3EA978C11093BBEC" modified="2014-04-16" version="1">MLVPKDLPEHLANEDKGPTILAVCIALTALATIFVAARLYVRGKIQSHIGLDDWLMILSMICGYVMLGLTIAAVRAGNGRHFVLLTTAQKSDAILYTIAGFCPGILSFGIPKLAVVALLTRIMNPSRGHAVFLWSMTSGCLLILLGCVVILFAQCTPTRSQWDFTVKGTCWSPWVLVYYAIVAGTISAIVDLYLAIYPAVVLYRLQMNVKKKIALSFALGLGSIAAAVAIYKSTRLPALASADFSYDTADITIWTSIEGNAIIIAACIPTLQPLIDRIFGRGVFGSTRGERGRSDYESHGQNATKLITIGSKTFRSSRRHKKTGISDTTIGQESQESILSFNRRHVNHRSKGEEDLVITRTQEVSVQVESISNHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5D9</accession>
    <name>W6Z5D9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1772 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_96201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963989">
        <property type="protein sequence ID" value="EUC45165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688300.1">
        <property type="nucleotide sequence ID" value="XM_007690110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5D9"/>
    <dbReference type="GeneID" id="19128807"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96201"/>
    <dbReference type="eggNOG" id="ENOG502SW17">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127761_0_0_1"/>
    <dbReference type="OrthoDB" id="3648235at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013901">
        <property type="entry name" value="Anthrone_oxy"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08592">
        <property type="entry name" value="Anthrone_oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="19990" checksum="9A7C5B232E19FD75" modified="2014-04-16" version="1">MAALEIAFYIIPFIHWGMIVSLFIVSGIAWSFNLWVVPIIKLNPSKSAIAQLLETSRRGGAWLEPLNASFAFMFGITAVLLSRHPDPSVASQWKPFAASFATLLQVAWWERVMIFPLEASIANLGKGKEKSGGIEGAWLDNETSKVLHKSLDEWSRWHAIRATLPLIGSLIAFVTKLQSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5H3</accession>
    <name>W6Z5H3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_102480</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964048">
        <property type="protein sequence ID" value="EUC42814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690671.1">
        <property type="nucleotide sequence ID" value="XM_007692481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5H3"/>
    <dbReference type="STRING" id="930090.W6Z5H3"/>
    <dbReference type="GeneID" id="19118090"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102480"/>
    <dbReference type="eggNOG" id="KOG1331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029501_2_0_1"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000219">
        <property type="entry name" value="tRNA (Carboxymethyluridine(34)-5-O)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="53"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="268" mass="30240" checksum="AB48B66C63CF594C" modified="2014-04-16" version="1">MASQDEPPQSYEATHVHAVYEEIAEHFSSTRYKPWPIVDRFLREQRDGAVGADVGCGNGKYLGVNDKVWIVGSDRSTNLVKIARRHEPHDVVVADNLALPHPGGIFDFAISIAVVHHLSTLERRVEAVKSVLDLLQPPSKSGHEDSSHGNGTADTSTTGGRALIYVWALEQKDSRRGWDEGHEQDVMVPWVLKQKKEKEAKRKKNKDNGMQENGSEEKGRTAEGDKTFLRYYHLYRKGELENDIEQAGGVVLESGYEKDNWWAIARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6T4</accession>
    <name>W6Z6T4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="10">P5C dehydrogenase</shortName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
                <ecNumber evidence="9">1.2.1.88</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_5245</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate 5-semialdehyde + NAD(+) + H2O = L-glutamate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="9"/>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687912.1">
        <property type="nucleotide sequence ID" value="XM_007689722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6T4"/>
    <dbReference type="STRING" id="930090.W6Z6T4"/>
    <dbReference type="GeneID" id="19124542"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5245"/>
    <dbReference type="eggNOG" id="KOG2455">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_4_1_1"/>
    <dbReference type="OrthoDB" id="5322683at2759"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:L-glutamate gamma-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07123">
        <property type="entry name" value="ALDH_F4-17_P5CDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000006">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000005">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005931">
        <property type="entry name" value="P5CDH/ALDH4A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050485">
        <property type="entry name" value="Proline_metab_enzyme"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01236">
        <property type="entry name" value="D1pyr5carbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862:SF1">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="11">
        <location>
            <begin position="94"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC45523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="584" mass="63575" checksum="78E98D86B2D1EFE5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6X2</accession>
    <name>W6Z6X2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687947.1">
        <property type="nucleotide sequence ID" value="XM_007689757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6X2"/>
    <dbReference type="STRING" id="930090.W6Z6X2"/>
    <dbReference type="GeneID" id="19128613"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95240"/>
    <dbReference type="eggNOG" id="ENOG502R1TU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032660_0_0_1"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886535" description="Amine oxidase domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="52333" checksum="AD6331EDFA6D9B52" modified="2014-04-16" version="1">MWSLLVSLVALPSLVLSAPTGDSHHHKNPVCIIGAGPAGLAAAGRLKDKGISAVVFDRQEKVGGKCQSWYDEKGIFHPLGAAFFSNGTYTETVGILNKTDVAIESFSLAGARSQYIYNFTNGDILPYPALSAQFSAMVASEIPRYVVLWNERFRPASALNYRDGVPHEFTLSGAEWFRQNNFTALPLILVNAVALYGYGDINIVPALYILKYFTPDILTAFAGIRNVYYMDFHKMFAEYTEKELCETPIYTSADVRCVDRSGPNPVLTYTVPKGNFVSWNKQECSSVIFAFPPSLDNLQRVGVDLTEEEHNTFANVTTHQYYSSAVELELPFGVSYVAASASPSVPPPNDGEPVAILRLSQQSNVSVAWSWGPYEFQTEAAAKRLLIDSLSAINKDPRNATAKPSPFTEEDVKAFRKWDYFPHFGSEALAAGAYEKYNNLQGCKKTYYASGISGMEIVEWAVRSGYDIVDRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6Y2</accession>
    <name>W6Z6Y2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_50760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964516">
        <property type="protein sequence ID" value="EUC39441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007694040.1">
        <property type="nucleotide sequence ID" value="XM_007695850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6Y2"/>
    <dbReference type="STRING" id="930090.W6Z6Y2"/>
    <dbReference type="GeneID" id="19124492"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_50760"/>
    <dbReference type="HOGENOM" id="CLU_000288_34_12_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21395" checksum="FDC501A0774BA707" modified="2014-04-16" version="1" fragment="single">MAKNHQFTIGWICPLPLEKEAARLVLDEEYPQDEVQHQNTYYLGGRIGKHKVVIGVQRRIGLTGAAILAEKMRTGFPNIKYFLLVGIAGGVPRYGQPGAFSEIVLGDVVVSSPRSNHGGVLQYDKGAWEGQGRLNFRGHTNGVPGDLMAAVNNFRAEGWSKTNIAQVLKQMRLKLNEEQKRQYADPGPSQDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7E0</accession>
    <name>W6Z7E0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TAFII55 protein conserved region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_3441</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF7 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685818.1">
        <property type="nucleotide sequence ID" value="XM_007687628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7E0"/>
    <dbReference type="STRING" id="930090.W6Z7E0"/>
    <dbReference type="GeneID" id="19122554"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3441"/>
    <dbReference type="eggNOG" id="KOG4011">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016434_1_1_1"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08047">
        <property type="entry name" value="TAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037817">
        <property type="entry name" value="TAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006751">
        <property type="entry name" value="TAFII55_prot_cons_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12228:SF0">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12228">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04658">
        <property type="entry name" value="TAFII55_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01370">
        <property type="entry name" value="TAFII55_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII55 protein conserved region" evidence="7">
        <location>
            <begin position="196"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="364"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="453"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="459"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="473"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="559" mass="61436" checksum="6E2835DD5914397E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7H5</accession>
    <name>W6Z7H5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_4897</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687497.1">
        <property type="nucleotide sequence ID" value="XM_007689307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7H5"/>
    <dbReference type="GeneID" id="19124425"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4897"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016134_0_0_1"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF3">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="354"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC45955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="677" mass="75339" checksum="A8F7B4FFD71A4CE2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7R9</accession>
    <name>W6Z7R9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964269">
        <property type="protein sequence ID" value="EUC39721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693759.1">
        <property type="nucleotide sequence ID" value="XM_007695569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7R9"/>
    <dbReference type="STRING" id="930090.W6Z7R9"/>
    <dbReference type="GeneID" id="19119654"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110745"/>
    <dbReference type="eggNOG" id="KOG1014">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_17_0_1"/>
    <dbReference type="OrthoDB" id="5399006at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431:SF7">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="26227" checksum="11851F170D094FE2" modified="2014-04-16" version="1">MTSRLIAVVAGVGPGTGASVARKFSAKYPVVLLARKPENYESLAQEINSKGGKAIGISTDVSDAGSLESAVAKIKEEFGADVGAAAAIFNASGGFLRKPFLEVGADVFQASLGVSAMGGILFSQSFLPLLLKGVQQQSEYAPSLIFTGATASVKSNAQMASFSTGKWALRALSQSLAREFGPQGVHVAHAIIDGVIDIPRTKEWLKDMPAEAKLSADAIANDYWWLHTQPKTNFTWEIDLRPAVEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z918</accession>
    <name>W6Z918_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_45094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687224.1">
        <property type="nucleotide sequence ID" value="XM_007689034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z918"/>
    <dbReference type="GeneID" id="19124265"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_45094"/>
    <dbReference type="eggNOG" id="ENOG502SUKT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129992_0_0_1"/>
    <dbReference type="OrthoDB" id="3647at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="137" mass="15347" checksum="4F8BB95ED6179BFD" modified="2014-04-16" version="1" fragment="single">MGIPYSRQINAAFEQVTPLVAAGFTVLRTTRDISILLAIIQVLTVLLLALILGVLVAMLYCINPDLEEERKRIITPWLRYAAQISIWGVMKFVVGIVVMWSVASAAVWKGIVAKQWVEDVEYEGNVRAEMALEELDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z934</accession>
    <name>W6Z934_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PLAC8-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687218.1">
        <property type="nucleotide sequence ID" value="XM_007689028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z934"/>
    <dbReference type="STRING" id="930090.W6Z934"/>
    <dbReference type="GeneID" id="19122939"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36105"/>
    <dbReference type="eggNOG" id="ENOG502S5E0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_600114_0_0_1"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="55097" checksum="3D7FF79596C4724C" modified="2014-04-16" version="1">MDPRNYGRSQEAQPQMTSRQHTRFSWQQPLDDEVPPYQERQRQAPQHQPQQLATQQYQTQQQYQQYQQPQQQQQQQQQYQHQHHQQQQQQQQHQQEPQQRVETDASRHFSYAQTPAEMRAFVYTSSPSDPPMPHSMPISLPTSPVGYTPIDPRPQSMFDAQIPVVPPQSRAADMQHSHVQQVQPPVSPVSPQHSSYPQTQQYSPVSPIPHPQPAHQGPQANTQQSRHARQMSNLSPINTNVRVHTMPTIPPTPPSGTHQTSPLPQKAPITPISANSMHKEQPRQVATSPTNQASYAHEPYSPHGFVTGQTNNMHAVFSPDAAHGPNGLDFAAHQPGQISHPNMESESSHEWSSGLCACSPEPTTCFTGLFCPCIIYGRTSYRLSQKSAKNDPTDMLGHSTTNGHCVVMGLSCGLWWLFPMLQRTRIRRAYKIKGSLGSDLLRGCCCCCCVVVQNEREVKGREEASRRWAGPASTDVYTRSGDMVYKPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z946</accession>
    <name>W6Z946_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_109440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964188">
        <property type="protein sequence ID" value="EUC40191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693286.1">
        <property type="nucleotide sequence ID" value="XM_007695096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z946"/>
    <dbReference type="GeneID" id="19119432"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109440"/>
    <dbReference type="HOGENOM" id="CLU_748042_0_0_1"/>
    <dbReference type="OrthoDB" id="5329176at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="36"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="348"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="370" mass="41535" checksum="AECA24F62EE519CD" modified="2014-04-16" version="1">MALKPGDPGYMEQDVSPTLYSITFSCLGFALLIVTLRLFSRLYILKTTRLNLAEWLVVVSSVDIASCVLIHFQIVTGMGKHIEYSRARPKMLEASMKVGLAQNSVYQALVGLIKASMLAQLHLLAAPGMQKKVEFWTGCLVCIFTIFTTFAAIFQCIPMSAAWSIDTFPRGCWNMMAMNFFTSTVNTIFDFIIFFLPLPTLLGLKMKRKKKVVSLIFTYCAGSLAIACSIVRLRNMIYFRGVGDFTYHASMVPVWGAIECNAGIVCGSFPYIMPLIKRMSGSIVDSIGVSRANPTLNQQHDGQHSKQLSWPLQSKRQSRWHQMDSESIEAITENSGWKELDHIKKTQHHVEHSVPVEHTPHIPTLPYDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9E9</accession>
    <name>W6Z9E9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane BAX inhibitor motif-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_2789</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685109.1">
        <property type="nucleotide sequence ID" value="XM_007686919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9E9"/>
    <dbReference type="STRING" id="930090.W6Z9E9"/>
    <dbReference type="GeneID" id="19121202"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2789"/>
    <dbReference type="eggNOG" id="KOG2322">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058671_0_0_1"/>
    <dbReference type="OrthoDB" id="7933078at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd10429">
        <property type="entry name" value="GAAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF50">
        <property type="entry name" value="PROTEIN LIFEGUARD 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31244" checksum="8C13C0662ED8C131" modified="2014-04-16" version="1">MAGPKYQNVPQRDSLDETAPAPSYSQAPPSYQATEPQEALLSGVPRSEDDNLPDDFKFGGVVAEATLDIRMAFIRKVYAILTVQLLATAAVSFVSMTSVTYRNWIQTHSWPLWVSMFGSFAFLGLTYWKRKSYPTNLMFLAGFTAMEAYMISVIVSFTESKIVLQAVFFTLGIFIALSLFACQSKYDFTSWVPYLFGALWVVVLFGFMSAFFPYNSTVDLGYGIVCALIFSGYILVDTQLIMRHYHVEEEIAAAISLYLDIINLFLAILRILNSQNQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9N2</accession>
    <name>W6Z9N2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_23818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685017.1">
        <property type="nucleotide sequence ID" value="XM_007686827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9N2"/>
    <dbReference type="GeneID" id="19120497"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23818"/>
    <dbReference type="eggNOG" id="ENOG502SS66">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_619609_0_0_1"/>
    <dbReference type="OrthoDB" id="5366256at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="47606" checksum="8F29F386CB6407E7" modified="2014-04-16" version="1">MTHWSSNPHQPKTTTISRRLRDRANQHLSVQPPEIPQIRGPYSCRAATLPTPRHNPIDYQTPGSHLPSLAWNTSHILDDTSHNRFSQPNSPAQDRFLDSTSAQTTHFSLDESHPGSDSTVVPTTSNQIVRTDHILLTQSQQTPTSPSVSTSTGHSLQLQSLADFEQPHDPILESQDMSTLGFMMPSSQYGMGHYGSSQTSYAPGYPPSQPYGEPRASAPGPYGPPYSSSPAPNESQQRRSEQHAVQPPYPPQHPSLPRSPYEQHSSDHMRANTASMGTNTHAYTYSTSHSTIPNQPLGGNAYPPSYAVSDYHPLPTMYPPNNTAPATYATYDSPSSAPVSNASVPALSSSPSTQGNPVMPRVINSRPKPQCWEHGCNGRQFSTFSNLLRHQREKSGTASKSTCPRCGAEFTRTTARNGHMAHDKCKPRRPSETKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9X9</accession>
    <name>W6Z9X9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_92486</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686918.1">
        <property type="nucleotide sequence ID" value="XM_007688728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9X9"/>
    <dbReference type="STRING" id="930090.W6Z9X9"/>
    <dbReference type="GeneID" id="19128087"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92486"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902181">
        <property type="term" value="P:verruculogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000063">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC46583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="518" mass="58309" checksum="6D88BAF92AEE0F5C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB19</accession>
    <name>W6ZB19_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PSI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_91234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC47008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686513.1">
        <property type="nucleotide sequence ID" value="XM_007688323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB19"/>
    <dbReference type="STRING" id="930090.W6ZB19"/>
    <dbReference type="GeneID" id="19127839"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91234"/>
    <dbReference type="eggNOG" id="ENOG502SXHK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113404_0_0_1"/>
    <dbReference type="OrthoDB" id="5427091at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="24289" checksum="1C8282CEF2F6B9A0" modified="2014-04-16" version="1">MPSNCPATSSAAKRDNDAWINATELFHHRLQSSPKEDWDRLKLCWGYMDCGDCHRSKGHCGWCAISSTCLPLPLDGFSRAFPLLSPIRHHSICALGSERFELRTAGLGCQVSTITFLTSLVTIFCTLFGVLVLYGVSKCVGWVVVGTRARRGGWVVYEDGSSGLWVREREGWGTLWRRVGGRQREEDVLEVDEGTRRRGFVWWGAAREERRPLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB96</accession>
    <name>W6ZB96_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1479 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_107347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964126">
        <property type="protein sequence ID" value="EUC40996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692488.1">
        <property type="nucleotide sequence ID" value="XM_007694298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB96"/>
    <dbReference type="GeneID" id="19119026"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107347"/>
    <dbReference type="eggNOG" id="ENOG502QWFN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011148_0_0_1"/>
    <dbReference type="OrthoDB" id="8249012at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010856">
        <property type="entry name" value="Gig2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613:SF1">
        <property type="entry name" value="DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBIU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07350">
        <property type="entry name" value="Gig2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="56976" checksum="81DC091C0D15D205" modified="2014-04-16" version="1">MMLSALRTIRSPTTRAATQVRTVATQPQRRAGDISDAFASLSGHDFKPLTPEYADLKARLIRGHESEVRDSWDRLLRNLRDEIPRIAEQGSKVIPEIDFKDIDNAPEVFSSQLRERGVAVVRGVVSEQQALQWKEDLREYIRQNPQTKAFPADNPQVFELYWSRPQLLARGNPNLLKAHRFLMSFWHSSNPHIPLSTKHPISYADRLRLRQPGDARFSIGPHVDGGSVERWDEQGYGLGKVYDSIWKGKWEEFDPWEASCRLPIVPDLHQGVGACNAFRMFQGWLSLSTTRPLEGTLLVNPLFAKATAYYMLRPFFSPKRGVEPGAQTASEATTNTSAFLSPDNWEMDSPQTSWIHGATPGHGQELSNLLHPHLHLQKTMVHVPTVRPGDYVAWHCDTIHSVDKKHQGTSDSSVLYIPACPMTEDNANHLVRQRNTFVNGTPSPDFGSGIGESEHVGRVLPDEMQKLVGDEGCRAMGLLEWDSEEPGLGPGEKVILDRANKILGFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBE3</accession>
    <name>W6ZBE3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_24759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686148.1">
        <property type="nucleotide sequence ID" value="XM_007687958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBE3"/>
    <dbReference type="STRING" id="930090.W6ZBE3"/>
    <dbReference type="GeneID" id="19120636"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24759"/>
    <dbReference type="eggNOG" id="ENOG502TCKK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068279_0_0_1"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="22"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="369" mass="41628" checksum="6B00484A269F9DEC" modified="2014-04-16" version="1">MPFMNSKGATTLGHTFRNFDQTIITVKVGAKEHPESFSCHRELLRRCSTYFNTCLEEQSSSPYNSSSLTLELEDTSPDVFDAFMLWLYTGFIPHHLIEGGKEIHPPTHAISVNGSDSTSAPPTEQGEGDDVDTASWGIALDDETPADGASAPAEATNSPTTTSAEKVQGEVEVEKPPVVLPPRNPAEKPEIPKETLCPCCSRPYKWRSLEGFLERRFISLYVFAHKYSIPKLSRAVILAWQTNDEILQVMPDHSNVIAAYESLPPDAPLCRYFLDMYSVYWNPDRDDERTIPLRSHLPQAFLFELVTMLARGERPKMEKEWCEFHEHESEEEKKACLDDLAKDPIASKALRRIKDSKGWKGLVLKKGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCB1</accession>
    <name>W6ZCB1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UMP1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_3537</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685965.1">
        <property type="nucleotide sequence ID" value="XM_007687775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCB1"/>
    <dbReference type="STRING" id="930090.W6ZCB1"/>
    <dbReference type="GeneID" id="19122768"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3537"/>
    <dbReference type="eggNOG" id="KOG3061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036918_1_0_1"/>
    <dbReference type="OrthoDB" id="15001at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05348">
        <property type="entry name" value="UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="50292" checksum="D71554A692C654DE" modified="2014-04-16" version="1">MKPIIAVPGIAALIYRAWSRNSLTPVGILAAFVTAVIHTVHPWSVFTVLLAVFFLAGSSVTKVKHDIKAKLTQSATGASGGEGARNHIQVFANSGIASVLILLHLWQLRKDGRYEDEGLCWTGNSDILVTGIVANYAAVAADTFSSELGILSKSKPRLITAPWRIVPPGTNGGVTTTGLGAGLLGALIISLSSTMFMPFCKDWSFAEKTKYTLALTAAGFNGTLLDSLLGALLQASVVDVHSGKVVEGEGGRKVLVHSKEGVTKATGTDAAGSIKASKAMLKAGASGTAVADPQHESRKIEVGSDLLDNNAVNVLMAGLSLRFVPSKAHPAQTTLETSAPSAPGVHDTLRSRLGHTSVAPTASSSSTAPVALQSAHPLEARLVQWRETQDRLKMEMLRRQFGIAEPVRRGMELKIAEAGEWRPLALGGSSSVHKDILQGRDCEIGWEDVFTGNELREVPDFHTEIEKKMKMNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD63</accession>
    <name>W6ZD63_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_34656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685589.1">
        <property type="nucleotide sequence ID" value="XM_007687399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD63"/>
    <dbReference type="GeneID" id="19122607"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34656"/>
    <dbReference type="eggNOG" id="ENOG502S7FQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084831_3_0_1"/>
    <dbReference type="OrthoDB" id="2253354at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035213">
        <property type="entry name" value="DUF5321"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17254">
        <property type="entry name" value="DUF5321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="208" mass="23826" checksum="B857F905D68859F6" modified="2014-04-16" version="1">MDPSIIFRQLLRMPAAHRNALLQPTRPHMRAFAAYTQPLPQPRYLSVPRIVQPSFWASLTPKPFKTRSETPRSKEWNPATPYIILGLLVGSQAIQILWLKQERNHDLRRAEAKIGILREVIERVQRGEKVDVEGALGTSNAVEEREWKQVLKDIQDEEALFQSKKKRRAMREAALQEEAAEKKTGQESTKSQDAAKMQVESVGGVKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDX9</accession>
    <name>W6ZDX9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_32634</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683416.1">
        <property type="nucleotide sequence ID" value="XM_007685226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDX9"/>
    <dbReference type="STRING" id="930090.W6ZDX9"/>
    <dbReference type="GeneID" id="19122147"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32634"/>
    <dbReference type="eggNOG" id="ENOG502QT45">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006746_1_0_1"/>
    <dbReference type="OrthoDB" id="546893at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050375">
        <property type="entry name" value="MFS_TsgA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702">
        <property type="entry name" value="L-FUCOSE-PROTON SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702:SF13">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="575"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="700"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="756"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="782"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="5">
        <location>
            <begin position="34"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="323"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="813"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="815"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="842"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="852"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="888"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="903" mass="99565" checksum="E45264275BF4BE55" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE56</accession>
    <name>W6ZE56_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Carnitine O-acetyltransferase, mitochondrial</fullName>
            <ecNumber evidence="16">2.3.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_8514</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA</text>
            <dbReference type="Rhea" id="RHEA:21136"/>
            <dbReference type="ChEBI" id="CHEBI:16347"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57589"/>
            <dbReference type="EC" id="2.3.1.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.7" evidence="16"/>
    <dbReference type="EMBL" id="KI964085">
        <property type="protein sequence ID" value="EUC41801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE56"/>
    <dbReference type="STRING" id="930090.W6ZE56"/>
    <dbReference type="GeneID" id="19126612"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8514"/>
    <dbReference type="eggNOG" id="KOG3717">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013513_5_1_1"/>
    <dbReference type="OrthoDB" id="240216at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009437">
        <property type="term" value="P:carnitine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.70:FF:000007">
        <property type="entry name" value="Carnitine O-acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF103">
        <property type="entry name" value="CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00439">
        <property type="entry name" value="ACYLTRANSF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 19" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="20">
        <location>
            <begin position="33"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00052702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00053195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00066910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00073438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC41801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="608" mass="69473" checksum="198463CAEC752341" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE64</accession>
    <name>W6ZE64_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_105144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964085">
        <property type="protein sequence ID" value="EUC41811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691673.1">
        <property type="nucleotide sequence ID" value="XM_007693483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE64"/>
    <dbReference type="GeneID" id="19118636"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105144"/>
    <dbReference type="HOGENOM" id="CLU_2621664_0_0_1"/>
    <dbReference type="OrthoDB" id="4492972at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8723" checksum="B75E74EF4AB2C788" modified="2014-04-16" version="1">MSSSASETVVEKYRYEILFGTWLAVTGATFLRIKRQPYSTRLKIEQYESIFKGTSLSAVLIGIGITPARSTARRFTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEK5</accession>
    <name>W6ZEK5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sulfite oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_34179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685137.1">
        <property type="nucleotide sequence ID" value="XM_007686947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEK5"/>
    <dbReference type="STRING" id="930090.W6ZEK5"/>
    <dbReference type="GeneID" id="19122499"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34179"/>
    <dbReference type="eggNOG" id="KOG0535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030575_0_0_1"/>
    <dbReference type="OrthoDB" id="10051395at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF6">
        <property type="entry name" value="SULFITE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase molybdopterin-binding" evidence="1">
        <location>
            <begin position="168"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Moybdenum cofactor oxidoreductase dimerisation" evidence="2">
        <location>
            <begin position="278"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="43937" checksum="0BC2E0B02B565D8D" modified="2014-04-16" version="1">MTDSKRQVGTTNQLTIDEEAIRTVGDRGKLFGRERKGWVGFVEWKDHPDKKLGPIPGTRWKMWHHAVGDEITQIPGDPWDIVLKEKHPDILRLLQFPYNGEPPKRFFTDREITLNPLHLSGTMVTPRLLTLDGLMDQTKFPHIEKVVTIQCSGTRLIEQILKYPDDKVMNYLVSVPWSKVKENEVLLAWEMNGEPMPRIHGCPLRLVILGYIDARSAKWVYRTKAIEKPSRAPVQSQKYLYFPQQVGKHELGLTDWIQAQKMSVSSAVMSPWTKQVPKRIELSADGGFNWYTVPFKNMSKKRKWIWRTYKFDLPYDLEGRVEIVYQCWDNALNTQPPDVRTAWNWVLYVTNSCHRISVYSVNKSSSKIYCSRCLKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFY0</accession>
    <name>W6ZFY0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_25512</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687022.1">
        <property type="nucleotide sequence ID" value="XM_007688832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFY0"/>
    <dbReference type="GeneID" id="19120775"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25512"/>
    <dbReference type="HOGENOM" id="CLU_1927229_0_0_1"/>
    <dbReference type="OrthoDB" id="10639583at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="131" mass="14277" checksum="45796FA8879B8B65" modified="2014-04-16" version="1">MGIGDAREIKWAKCTAPAPSTGDRGRRARECRGSAPGYEGTEALLQASTLYIRDGCVPPRRPRLALVHISACCAFQSQCAPGEAARFGLHVSRMGRPAPFLILSQQLGRRRRHARHRLRGNTSPGHCCLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG99</accession>
    <name>W6ZG99_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_39425</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964058">
        <property type="protein sequence ID" value="EUC42531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690952.1">
        <property type="nucleotide sequence ID" value="XM_007692762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG99"/>
    <dbReference type="STRING" id="930090.W6ZG99"/>
    <dbReference type="GeneID" id="19123686"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39425"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_2_1"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF34">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="355" mass="38488" checksum="BCB1D687DCD7350E" modified="2014-04-16" version="1">MLRFLHRVLRAVLRSIWWKKNKLVLSADNKTLAVGSGNHWKSIYDYLALSNLAVVGGRASTIGVGGLTLGGAITHHTNKYGLACYSVASYEIISASGAIVTVSEQTYPDLYLALCSGGNNFGIITTFNYEIFPQCLMFPSKRQYSATHIPALFDAFGNTVQDAEEYFDPVDVSNPPDILNDYVSIPALNEATKNTTLAEITLGLTESMPAGLRKTMWSQLFKVNTELFSGGGASSIAFQAFTKPALRAMQRKGGNALGLRPDDGPFFRVVLYLAWTDEKDDKTIYKAAQDFLAASTAESQAADPYQPVISGYGADSVARLNKVSSKYDPKGVFQTLQPTSFKLNGEAPFGAVVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGG8</accession>
    <name>W6ZGG8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_103136</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="KI964056">
        <property type="protein sequence ID" value="EUC42591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690913.1">
        <property type="nucleotide sequence ID" value="XM_007692723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGG8"/>
    <dbReference type="STRING" id="930090.W6ZGG8"/>
    <dbReference type="GeneID" id="19118232"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103136"/>
    <dbReference type="eggNOG" id="KOG0549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040321_0_1_1"/>
    <dbReference type="OrthoDB" id="431202at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022127">
        <property type="entry name" value="STIMATE/YPL162C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735:SF1">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12400">
        <property type="entry name" value="STIMATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889813" description="peptidylprolyl isomerase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="9">
        <location>
            <begin position="41"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="441"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="140"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="512" mass="55870" checksum="7FF1D68C9A1354B0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGJ1</accession>
    <name>W6ZGJ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF967 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_39355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964055">
        <property type="protein sequence ID" value="EUC42611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690872.1">
        <property type="nucleotide sequence ID" value="XM_007692682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGJ1"/>
    <dbReference type="GeneID" id="19123668"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39355"/>
    <dbReference type="eggNOG" id="ENOG502S03S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101036_1_0_1"/>
    <dbReference type="OrthoDB" id="2209940at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="entry name" value="Haem-degrading domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010371">
        <property type="entry name" value="YBR137W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255:SF1">
        <property type="entry name" value="UPF0303 PROTEIN YBR137W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="HbpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="GlcG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="20339" checksum="731C6FA0704FA965" modified="2014-04-16" version="1">MLGALPLPTRDLAELAKEEKGFTFNHFTCEHAWVIGNILRNALRTAECPVLIHIALSTQTLFHAPSLPGIMPDHEKWVERKRNTVLRWGHSTWYMGCQFDDDYKKFAEYHAMSGDEWSKYTIEGGGYPVFVKGVEGVVGAITIAGADISSVQAHSVVVKAVEEYKELRDGFRSPMRAATTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGR1</accession>
    <name>W6ZGR1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_23258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684402.1">
        <property type="nucleotide sequence ID" value="XM_007686212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGR1"/>
    <dbReference type="STRING" id="930090.W6ZGR1"/>
    <dbReference type="GeneID" id="19120401"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23258"/>
    <dbReference type="eggNOG" id="ENOG502R8N6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_762880_0_0_1"/>
    <dbReference type="OrthoDB" id="3794485at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="363" mass="40497" checksum="D2B493B5941AC53B" modified="2014-04-16" version="1">MDLIDREYPTSDDKPPWFGMKFKQSVYSDDMLESLKRRYPQGANLRERKHMAAIEFLQQELKNMQASEAALIPKTNPTTLVPDIASHNHQHQRTGSPPYSPTSQLSSPNIMDGYHGTRSPTNKVFLEQPPNVSSNVSGQEIVFSIGNRPLVQRQRRKKMTPAEKISYKQMRKIGACDSCKRQKAKCRHVGGERDRYRNSRGASSSPKRETRPISDSGTLTVDATNEHKSQTQAPQHSQDLSYDLKSSLETVSIATPVTVSGSPSPHWAQDMQGSAQSELSGYVPPSTTSKLYSSYPNATFESTIDPQLLDMNYRDPNIFNEANGVFLMSLTTGNTPSGSFYSRNTQEFWSPVQGCRTDGNPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGR9</accession>
    <name>W6ZGR9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_33564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684420.1">
        <property type="nucleotide sequence ID" value="XM_007686230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGR9"/>
    <dbReference type="GeneID" id="19122355"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33564"/>
    <dbReference type="HOGENOM" id="CLU_054430_1_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="167" mass="18673" checksum="8F3D06C0BDAE8132" modified="2014-04-16" version="1">MAAITRAVGQSGHRYLVKILLQEKPGALGRVYLVSDLKTSAYIRVADDAILDHSVFAYSFRLWKRVLRDSLWGIAALHEKGIVCIRTLSPITLWWIWEETGGNMAIPRVRIADIESAVHLAPNCVMMGAQVGNSMWWSHEAHASELKEGEGKLAVVLERQLSYCSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHF3</accession>
    <name>W6ZHF3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_35579</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686636.1">
        <property type="nucleotide sequence ID" value="XM_007688446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHF3"/>
    <dbReference type="GeneID" id="19122816"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35579"/>
    <dbReference type="eggNOG" id="ENOG502RXMI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_0_0_1"/>
    <dbReference type="OrthoDB" id="2525337at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF17">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 11" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886859" description="AA9 family lytic polysaccharide monooxygenase" evidence="12">
        <location>
            <begin position="19"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="13">
        <location>
            <begin position="19"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC46849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="334" mass="36051" checksum="A616B7DCA4486069" modified="2014-04-16" version="1">MAPNYALILSLLASQACAHTFIWGVFVNGVDQGTFTGIRIPGYNGQNGKGGYNNSPVKDLSSIDMRCNVMGDIQAHDTIKVAPGDNLTFDWHHELRNNTDEVIAYSHHGPSLIYISPDPPTNSSFVKLWHAGKIENNPFPQPGKWSTTADIRANYGRMNVRIPAGLKAGPYLIRAEMIGLHEGDVSFAQNPRRGAQFYPDCVQIEVVGEGEVELPEGVGFPGAYSYEDPGVVHNIYCSTETKKPTGSAAPCPTDYVIPGPMVWSGAWPETTAVAVGPIKGVSTATPWSTWIGTNSVVTSATYVDARSQTIVGSSKYTATWSEVYASPTATAPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHM2</accession>
    <name>W6ZHM2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_63191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684149.1">
        <property type="nucleotide sequence ID" value="XM_007685959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHM2"/>
    <dbReference type="GeneID" id="19124919"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_63191"/>
    <dbReference type="HOGENOM" id="CLU_417371_0_0_1"/>
    <dbReference type="OrthoDB" id="3687719at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019783">
        <property type="term" value="F:ubiquitin-like protein peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="297"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="582" mass="66626" checksum="3B4E63DA389B9310" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHN2</accession>
    <name>W6ZHN2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Iron-sulfur cluster assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_79874</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NifU family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682241.1">
        <property type="nucleotide sequence ID" value="XM_007684051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHN2"/>
    <dbReference type="STRING" id="930090.W6ZHN2"/>
    <dbReference type="GeneID" id="19125558"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79874"/>
    <dbReference type="eggNOG" id="KOG3361">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079283_1_1_1"/>
    <dbReference type="OrthoDB" id="1925777at2759"/>
    <dbReference type="UniPathway" id="UPA00266"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1010.10:FF:000005">
        <property type="entry name" value="Iron-sulfur cluster assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011339">
        <property type="entry name" value="ISCU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01999">
        <property type="entry name" value="iscU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="NIF system FeS cluster assembly NifU N-terminal" evidence="9">
        <location>
            <begin position="57"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC51357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="204" mass="21695" checksum="2CBA64C5BF9D88AA" modified="2014-04-16" version="1">MFRRVAAAVPAQAGRVLATAARPSIASPIRTAAPAVSAVGRRQYHEKDNNYLTYAALLDHYNRPRNVGSMSKTDSDVGTGLVGAPACGDVMKLQIRVDPNNNTISDVKFKTFGCGSAIASSSYLTELVRGMTLEDAARIKNTEIAKELCLPPVKLHCSMLAEDAIKSAISNYYTKNPKARQTDLGGKSAPLPKVEVETVSSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIG5</accession>
    <name>W6ZIG5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683817.1">
        <property type="nucleotide sequence ID" value="XM_007685627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIG5"/>
    <dbReference type="GeneID" id="19126371"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83997"/>
    <dbReference type="HOGENOM" id="CLU_3086882_0_0_1"/>
    <dbReference type="OrthoDB" id="10351461at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886877" evidence="1">
        <location>
            <begin position="17"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="52" mass="5407" checksum="FAE1C5EB40105203" modified="2014-04-16" version="1">MKLVAVLATILSVASAVAIPVELQERQCLNNGSFCTLPGGNLQCCTGFCHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZII8</accession>
    <name>W6ZII8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">COCMIDRAFT_7194</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">In the C-terminal section; belongs to the chitin synthase family. Class V subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">In the N-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC43376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007691910.1"/>
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    <dbReference type="eggNOG" id="KOG2571">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000192_0_2_1"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:fungal-type cell wall organization"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14879">
        <property type="entry name" value="MYSc_Myo17"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Chitin synthase ChsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.530:FF:000017">
        <property type="entry name" value="Chitin synthase ChsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000019">
        <property type="entry name" value="Chitin synthase ChsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000055">
        <property type="entry name" value="Chitin synthase ChsE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036037">
        <property type="entry name" value="MYSc_Myo17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF45">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 18" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 18" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10 18" id="KW-0518">Myosin</keyword>
    <keyword evidence="7 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="875"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="915"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1186"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1584"/>
            <end position="1605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1611"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1639"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="22">
        <location>
            <begin position="1"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="21">
        <location>
            <begin position="938"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="23">
        <location>
            <begin position="1782"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="589"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="18">
        <location>
            <begin position="655"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="589"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="95"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00046327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00046342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
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    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EUC43376.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1842" mass="205235" checksum="9264A92C5ECBDE91" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIK7</accession>
    <name>W6ZIK7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685478.1"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502T4Q0">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="3781412at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="70"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="119" mass="14484" checksum="EDFF76F96A1C45AC" modified="2014-04-16" version="1">MCIMRTYETRGRTVIEPPPRRGNFTSHPPAGVMRLPREWRRTESISDDGRYVEYRRSRSRPRVIEYYEEPRRSTTRARSVSRRRVTDVERRTPRTSYIDPRDSYVDERITRRSVSRVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIY3</accession>
    <name>W6ZIY3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_3640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007687869.1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_3640"/>
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    </dbReference>
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        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
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        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF16">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
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    </dbReference>
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        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="49"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="217" mass="23873" checksum="FBA197E33B1717E8" modified="2014-04-16" version="1">MSDPNFHITTPRLYLSYADPSNEAHIDFSLELINGAPALRSQGSTGTSAADRDAARKRIADTMTSLKNKGFGRYFVWLRPEPSSSSSSPSNTSTPFSSRALEPIGSVGLQLARLEGIKAPTIPDVGFIFLEKHQGKGYATEAVRVLMKYYEEEKGISVFSGFTKEDNEGARGLFRRLGFRNHGVRRVSGIMWSGEDIEADTWTWGVDEGVGLEEFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ51</accession>
    <name>W6ZJ51_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nitrogen permease regulator 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Required for meiotic nuclear division protein 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_89980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NPR3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686029.1">
        <property type="nucleotide sequence ID" value="XM_007687839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ51"/>
    <dbReference type="STRING" id="930090.W6ZJ51"/>
    <dbReference type="GeneID" id="19127592"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89980"/>
    <dbReference type="eggNOG" id="KOG3477">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3830">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014314_1_0_1"/>
    <dbReference type="OrthoDB" id="18648at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005365">
        <property type="entry name" value="Npr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153">
        <property type="entry name" value="CGTHBA PROTEIN -14 GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153:SF5">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03666">
        <property type="entry name" value="NPR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="643"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="870"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="256"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="673"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="688"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="734"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="882"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="897" mass="99519" checksum="34384D0F9E9564DB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJA4</accession>
    <name>W6ZJA4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_1091</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683237.1">
        <property type="nucleotide sequence ID" value="XM_007685047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJA4"/>
    <dbReference type="GeneID" id="19119368"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1091"/>
    <dbReference type="eggNOG" id="ENOG502SM2K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023111_0_1_1"/>
    <dbReference type="OrthoDB" id="258392at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF127">
        <property type="entry name" value="HISTIDINE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890065" description="Phosphoglycerate mutase-like protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="463"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="534"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="63147" checksum="CA61DF1D2387EE03" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJM5</accession>
    <name>W6ZJM5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_99860</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964019">
        <property type="protein sequence ID" value="EUC43796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689705.1">
        <property type="nucleotide sequence ID" value="XM_007691515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJM5"/>
    <dbReference type="STRING" id="930090.W6ZJM5"/>
    <dbReference type="GeneID" id="19129552"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99860"/>
    <dbReference type="eggNOG" id="KOG1305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009020_4_1_1"/>
    <dbReference type="OrthoDB" id="28208at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF458">
        <property type="entry name" value="SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="146"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC43796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="548" mass="59721" checksum="2F665D6F29B7EE0E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJN3</accession>
    <name>W6ZJN3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_82783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683338.1">
        <property type="nucleotide sequence ID" value="XM_007685148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJN3"/>
    <dbReference type="GeneID" id="19126128"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82783"/>
    <dbReference type="eggNOG" id="ENOG502SWHW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137468_0_0_1"/>
    <dbReference type="OrthoDB" id="5377039at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="154" mass="16832" checksum="6132544BACEA6C45" modified="2014-04-16" version="1">MELTPPSDRDGDSTMHSSPRNASDDEMFPDEALPNNPATPHNANLAAVNEISPPNSQSQTRETLGVNSNGKRPLSGGTMQSSATNPLGTSGTHTDPETGYQWSKQEDQPGYEWMNTRAREEENRALDNIVDKGYMIKLRYGDPLDASVAAKTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKA1</accession>
    <name>W6ZKA1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_99379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964014">
        <property type="protein sequence ID" value="EUC44011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689502.1">
        <property type="nucleotide sequence ID" value="XM_007691312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKA1"/>
    <dbReference type="GeneID" id="19129461"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99379"/>
    <dbReference type="HOGENOM" id="CLU_2928858_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01053">
        <property type="entry name" value="LSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="61" mass="6951" checksum="1F8AFCE0C953B911" modified="2014-04-16" version="1" fragment="single">CFLYALSMVERTVLGLLGGTSKIKCSPCWLSWNGPRGLCRNHTDVRSHPKMSLERPWKAYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKQ6</accession>
    <name>W6ZKQ6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ketoreductase (KR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_3044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685388.1">
        <property type="nucleotide sequence ID" value="XM_007687198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKQ6"/>
    <dbReference type="GeneID" id="19121677"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3044"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044999_0_0_1"/>
    <dbReference type="OrthoDB" id="2898509at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF2">
        <property type="entry name" value="KETOREDUCTASE (KR) DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="36693" checksum="8F693D0E9C2C4A33" modified="2014-04-16" version="1">MVAISAVRSHNATLKSVLPNPVAIFVGGTSGIGLFTARELVRHTVSPTVYLIGRNATEASKIVDELREINSASKVSFIQKDISLLKNVDEACNEIKSKEKHVNILFMTCGYLSVKGRDETAEGLDRKFSLHYYARMRFIQQLTPLMDAAAASNELSRVVAVLDPQAGLRLKGVNFADLSLKNTFSLKNVLVHASAMLSLSVAHLAKQHPKTTYIHAYPSGVQTGVTRQLFGPVNGAVKFALSAFGRLMFVPQEESGERHLFAATSPIYAPRVAAETTSMVGSDGVVGSGSYLLNWNGEILTDTNNARKLRDEGGVDKVWKHAEEVMKSIEERGSYSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKZ3</accession>
    <name>W6ZKZ3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CoA-transferase family III</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_98750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689254.1">
        <property type="nucleotide sequence ID" value="XM_007691064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKZ3"/>
    <dbReference type="STRING" id="930090.W6ZKZ3"/>
    <dbReference type="GeneID" id="19129324"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98750"/>
    <dbReference type="eggNOG" id="KOG3957">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033975_0_1_1"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047369">
        <property type="term" value="F:succinate-hydroxymethylglutarate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="entry name" value="formyl-coa transferase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050483">
        <property type="entry name" value="CoA-transferase_III_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207:SF3">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="49151" checksum="8F2988C61D27B584" modified="2014-04-16" version="1">MYSLARCSRPHLQFLSRQTPRQRAWVKRGIASTSSVDSKAVEKLPLAGVKVLDMTRVLAGPYCTQILGDLGADVIKIEHPTRGDDTRSWGPPNAPYVDGVERQFPGESAYYLSVNRNKKSVGLAFNNPTGTSILHKLVQQCDVLVENYLPGSLAKYKLDYATLSALNPSLIYASVTGYGQTGPYRDRAGYDVMVEAEMGLMHITGERDGPPVKVGVAVTDIMTGMYTAIGIQAALYARKSTGLGQWIDASLSDVQVSGLANIASSALVTGKGDSGRWGTAHATVVPYRAYATKDTNIAVGGCNDRLFKILCDKLSHPEWATDPRFLTNALRVQHRTTLDDMVEAELKTKTTKEWLDVFEGSGMPYAAVNDIKATVEHEHVLARGMIEEVDHKALGKVKLVNHPVKYSRAEPKIRMPPPLLGEHTDEVLREVLGYGEDKIRELRDTGIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL70</accession>
    <name>W6ZL70_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_87954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685270.1">
        <property type="nucleotide sequence ID" value="XM_007687080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL70"/>
    <dbReference type="STRING" id="930090.W6ZL70"/>
    <dbReference type="GeneID" id="19127167"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87954"/>
    <dbReference type="eggNOG" id="ENOG502S3AM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_8_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887183" description="DJ-1/PfpI domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="2">
        <location>
            <begin position="123"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="269" mass="29296" checksum="6148A9C240A643C3" modified="2014-04-16" version="1">MHFYQNAYLAAATVCTLISPCLSTPVQPPITNTSALPLHYGLVIFPHFQALDIFGPMDLINSLFMTYRNKTQEPHLSILSRTLDPVSSSMMPGGFGEAIMPTNTFKQYLSAHAPSNNTANTSVDGKPNIDVLIVPGGGGTRNDMSEEIAFIAATFPRLKYIISICTGASLLSRAGVLQGRRATTNKRSWAWATSHGENITWIPTARWVQDGNVWSSSGVSAGIDAMYAFVGNVYGKDVSTFMSLNLEYTRELHWDADPFAAVWDVPGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM41</accession>
    <name>W6ZM41_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_80403</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682447.1">
        <property type="nucleotide sequence ID" value="XM_007684257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM41"/>
    <dbReference type="STRING" id="930090.W6ZM41"/>
    <dbReference type="GeneID" id="19125663"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80403"/>
    <dbReference type="eggNOG" id="KOG2693">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015114_0_0_1"/>
    <dbReference type="OrthoDB" id="200954at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950">
        <property type="entry name" value="ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950:SF16">
        <property type="entry name" value="ZINC TRANSPORTER ZIP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890126" evidence="6">
        <location>
            <begin position="27"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC51135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="410" mass="42882" checksum="AB4BD6914A8FF77E" modified="2014-04-16" version="1">MVSRRNRTLLSLAIFIGVLAWNVAAAAVKGETGTPVENLTVHDIEEQLQECPLVQALNQHKVASNPTTSSLTAQIFAFLFPGSPAVNSLLATLYISGPPNFLLALCPPNIDPSSLSVMVAFAVGGLLGDTLFHLLPEIFLGEDEPNSVKFVMVEPNKNLLLGVAIMVGFITFVAMDKGLRIATGGAGGHDHSHGHSHEKVDATVKATGVDVDGSKDGVRARKGTADNKTAKASVTPDTEKEINASVKLGGYLNLIADFTHNITDGLALSSSFYASPTIGATTTVAVFFHEIPHEVGDFALLIQSGFSKRAAMGAQFVTAVGAFLGTCIGIAVQEFGGNSNSAVSTGPGLMGTSLQWGDMLLPFTAGTFLYVGTVAVIPELLETGPNKGQELRKTLLQFSAMFAGAGIMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMP1</accession>
    <name>W6ZMP1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RmlD-like substrate binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_31392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682126.1">
        <property type="nucleotide sequence ID" value="XM_007683936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMP1"/>
    <dbReference type="STRING" id="930090.W6ZMP1"/>
    <dbReference type="GeneID" id="19121859"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31392"/>
    <dbReference type="eggNOG" id="KOG0747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055718_0_0_1"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048269">
        <property type="term" value="C:methionine adenosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048270">
        <property type="term" value="F:methionine adenosyltransferase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="13"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="298" mass="33599" checksum="736644C95F1A5769" modified="2014-04-16" version="1">MSTSGKASDQVFLIWGGNSWIAGQLIQLLRDQGKQVVSTTVRMENREAVEKELDQVRPTHVLNCAGYTGVPNVDWCEDNKEKTIRSNVIGTINLVDCCFVRGIHVTTFSTACLYAYDEAHPIGGPGFRETDPSNFAGNFYSATKWHIENVIKHYGNCLILRIRMPVSDDLHPRSVVTKITQYDRVVNVPNSHSVLHELLPAAIILTEHNEKGVFNFVNPGAISHNEVLSLFKKHVRPSFTWKNFSVEEQNQVLKSGRSNCMLDTTKVQDTLRKYEYEIPEVHVACEQAFIRMASNGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNM3</accession>
    <name>W6ZNM3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF2264 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_85439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684328.1">
        <property type="nucleotide sequence ID" value="XM_007686138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNM3"/>
    <dbReference type="GeneID" id="19126664"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85439"/>
    <dbReference type="eggNOG" id="ENOG502R0FV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028269_1_0_1"/>
    <dbReference type="OrthoDB" id="5150166at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049237">
        <property type="entry name" value="DUF2264_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049349">
        <property type="entry name" value="DUF2264_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016624">
        <property type="entry name" value="UCP014753"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35339:SF2">
        <property type="entry name" value="DUF2264 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35339">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10022">
        <property type="entry name" value="DUF2264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20938">
        <property type="entry name" value="DUF2264_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014753">
        <property type="entry name" value="UCP014753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2264" evidence="1">
        <location>
            <begin position="14"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2264" evidence="2">
        <location>
            <begin position="383"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="703" mass="78792" checksum="D832770B83A67E07" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNR8</accession>
    <name>W6ZNR8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684340.1">
        <property type="nucleotide sequence ID" value="XM_007686150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNR8"/>
    <dbReference type="GeneID" id="19126661"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85426"/>
    <dbReference type="eggNOG" id="ENOG502SIQP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_7_4_1"/>
    <dbReference type="OrthoDB" id="3557394at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF82">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="41"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="651" mass="73448" checksum="8B5E5A2C97DC177F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNU4</accession>
    <name>W6ZNU4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688239.1">
        <property type="nucleotide sequence ID" value="XM_007690049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNU4"/>
    <dbReference type="GeneID" id="19123164"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37018"/>
    <dbReference type="HOGENOM" id="CLU_2721855_0_0_1"/>
    <dbReference type="OrthoDB" id="3687420at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887004" evidence="1">
        <location>
            <begin position="18"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="72" mass="7870" checksum="FB7075A79726AFDE" modified="2014-04-16" version="1">MKLAAVLLVALASIATASDGEALPRSCEECKMFFDACMRSCYFGRDTCPTTCGIDTCRVSSICKEHCDYKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNZ9</accession>
    <name>W6ZNZ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_95759</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963986">
        <property type="protein sequence ID" value="EUC45316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688139.1">
        <property type="nucleotide sequence ID" value="XM_007689949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNZ9"/>
    <dbReference type="STRING" id="930090.W6ZNZ9"/>
    <dbReference type="GeneID" id="19128721"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95759"/>
    <dbReference type="eggNOG" id="KOG1359">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015846_3_0_1"/>
    <dbReference type="OrthoDB" id="2382073at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF77">
        <property type="entry name" value="8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="5">
        <location>
            <begin position="34"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="415" mass="45284" checksum="C4AE08F5DDAB6996" modified="2014-04-16" version="1">MPSPPTPLEQTLSTHLSRRLTTSTLRTLTLPLPHQIDFSSNDFLSLSASPSLRTLFLSLLPPHLGSGGSRLLDGNSVLACTLESRIAAFHSADAGLLFNSGFDANAGFFAAVPQRGDTVVYDEKVHASVHDGMRLSRAARRVAFPHNSVEGLREVLEGEKEGKQNVFVAVESVYSMDGDVAPLREMVQVAEEVLGRERAYVVVDEAHATGVLGAKGRGLVCELGLEGRVFARLNTFGKALAGNGAIILGSHTLRSYLINYARPLIYTTFLSYPSLALIQASYEMLESGRSEALQAKLHDLIRTLYKRLEDLQRTSSHARRILKIPSVCPRSPIFAVQLANPKALASSLQEQGMMVRAVVSPTVPAGTERVRICLHAGNTVEEIEKLALALEKWCESQAEENTEHQPLDTLERARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP97</accession>
    <name>W6ZP97_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_33377</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684201.1">
        <property type="nucleotide sequence ID" value="XM_007686011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZP97"/>
    <dbReference type="GeneID" id="19122311"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33377"/>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_5_2_1"/>
    <dbReference type="OrthoDB" id="1535081at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF4">
        <property type="entry name" value="O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="189"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC49324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="356" mass="38642" checksum="1A86B71E29894BC1" modified="2014-04-16" version="1">MVSQFSLAETPIGKYFASMAELGIMRVFVEHGIFDAIPEEGISLENLTAQLGVEYNLIERFTAFLIAIDVLKSPAPGHVAHTSTSKAFTDARVGQFYTYLFDFFMGPTTQWPGYFATNGLAEPPRSNRSPGGFAMGMPDKTAYEIMAAIPGLATKMNGAMAIDGDIPITGVYDFSWVSAYAAGNADRELIVDVAGGKGQALKEILEESPAIPAARCVLQDQPHVIAEAVEEHKDSAILGPVKKIGHSIFGEQPIKGALVYYIRRVLNDWSDFEALQILKNIRTACADDSRVLIAEYLRPEDPSVYTSTVDMFILNIGGKVRSEKAFGELAAQAGLKIVSVAKHEKTESAVVEMIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPM9</accession>
    <name>W6ZPM9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_33085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC49444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPM9"/>
    <dbReference type="GeneID" id="19122239"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33085"/>
    <dbReference type="HOGENOM" id="CLU_132178_0_0_1"/>
    <dbReference type="OrthoDB" id="10425841at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="118" mass="12859" checksum="39C80D7C4390CD68" modified="2014-04-16" version="1">MRIHVFAAVDSGDSCHLPALQLAEPGVGSSLSRFLPLRSMLLISLLQSGSSSSRKVHSCLKLRVLGYVLAMCYTLRPGFRGRNVVNCTEPCCAISAKWLTWSFVNDSCTRIASQISLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQH6</accession>
    <name>W6ZQH6_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_1586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683725.1">
        <property type="nucleotide sequence ID" value="XM_007685535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQH6"/>
    <dbReference type="GeneID" id="19119896"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1586"/>
    <dbReference type="eggNOG" id="ENOG502SEIX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042177_0_0_1"/>
    <dbReference type="OrthoDB" id="5391950at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="301" mass="32944" checksum="832DEA0D0C17B736" modified="2014-04-16" version="1">MPTQLAHPSPKRKRDQPAPIPLLNTALALRPALESRPRDTSAPSSGGDSPRNAVADQLRDMTLTALAAIPLSPLTPTDDVLRKRPKLDATRVDSIVGPSTESVQETPTKYNKNNRDAFDIGAGTPVAESSRVIPKTPQSSQPRLLPDIASFAQPTIFASSPASKSAQPHVSADHELQAQHGSPSRSHARKRSPTPPPPTLTWQDSEITGHLVDPSTDPDDDGTGINGIGFKPTPALAYARSQKRRQQLNEWKLRETREARARRSERRLRGVRATPSREGTVEREVMSMKKVETRRTVKFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQJ2</accession>
    <name>W6ZQJ2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycosyltransferase family 31 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_36376</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687517.1">
        <property type="nucleotide sequence ID" value="XM_007689327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQJ2"/>
    <dbReference type="STRING" id="930090.W6ZQJ2"/>
    <dbReference type="GeneID" id="19123006"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36376"/>
    <dbReference type="eggNOG" id="KOG2246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_408295_0_0_1"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF47">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887649" evidence="8">
        <location>
            <begin position="25"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="54"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="444"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="448"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="528"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="629" mass="71490" checksum="BA900FBCF97ED3DA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQQ3</accession>
    <name>W6ZQQ3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_83479</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683685.1">
        <property type="nucleotide sequence ID" value="XM_007685495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQQ3"/>
    <dbReference type="GeneID" id="19126264"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83479"/>
    <dbReference type="HOGENOM" id="CLU_2793609_0_0_1"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="68" mass="7520" checksum="AD1223C50077D946" modified="2014-04-16" version="1">MNGHLQVVQILLNAGANANDCVDSQSRLYSHALHLAALRNDDKVVKMLLSAGALFSEGFRRDYPQYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZR23</accession>
    <name>W6ZR23_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dimethylglycine oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_83186</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683580.1">
        <property type="nucleotide sequence ID" value="XM_007685390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZR23"/>
    <dbReference type="STRING" id="930090.W6ZR23"/>
    <dbReference type="GeneID" id="19126205"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83186"/>
    <dbReference type="eggNOG" id="KOG2844">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_11_2_1"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032503">
        <property type="entry name" value="FAO_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF2">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16350">
        <property type="entry name" value="FAO_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase central" evidence="6">
        <location>
            <begin position="381"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="GCVT N-terminal" evidence="4">
        <location>
            <begin position="438"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="5">
        <location>
            <begin position="747"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="821"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="821"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC49954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="850" mass="93738" checksum="F33D10D10495353B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTY9</accession>
    <name>W6ZTY9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_80801</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682629.1">
        <property type="nucleotide sequence ID" value="XM_007684439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTY9"/>
    <dbReference type="GeneID" id="19125741"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80801"/>
    <dbReference type="eggNOG" id="ENOG502QPVD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028452_3_1_1"/>
    <dbReference type="OrthoDB" id="546893at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050375">
        <property type="entry name" value="MFS_TsgA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702">
        <property type="entry name" value="L-FUCOSE-PROTON SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702:SF3">
        <property type="entry name" value="PROTEIN TSGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="459"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="52958" checksum="7A84DF0958368301" modified="2014-04-16" version="1">MGFLRHPRLRNRDDQRTRAAELTLRESIGPLCLVTILFFLWGFSYGLIDTLNKHFQTTLGITRSRSSGLQAAYFGAYPLASLGHANWILRHWGYKATFIWGLTLFGIGALLAWPCLVYRSFGGFCAATFVIGNGLGSLETAANPYLAVCGPPKYSEIRINVAQAFNGIGTVVAPVLASYVFFDNVGTDKKSLENVQWTYLGIACFVFALAVVYYFTDIPEITETDADMAFQAESANAGSDVEPFRKQYRLFHATFAQFCYTGAQVAIAGSFINYVTETRVKNGRVTTNATASRFLAGAQGCFTAGRFAGSAIMKVTKPRWVFLTFMTMCIIFIIPAITERGDTGMSMLYVVLFFESIIFPTIVALGMRGLGKYSKRGSGFIVGGVAGGAVVPPLLFAASDSLGKPRPLDGYAPTATAMTVPLAFFVAASTYAICVNFVPAYTKVVDSFSTTEIGITNAHANDPENQIVHGDKAVSPDHTEHVDGETKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU00</accession>
    <name>W6ZU00_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_31581</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682336.1">
        <property type="nucleotide sequence ID" value="XM_007684146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZU00"/>
    <dbReference type="STRING" id="930090.W6ZU00"/>
    <dbReference type="GeneID" id="19121899"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31581"/>
    <dbReference type="eggNOG" id="KOG0569">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1284">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016208_0_0_1"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001591">
        <property type="entry name" value="PRK00393.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="13">
        <location>
            <begin position="17"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="241"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="493"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="643"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="495"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="519"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="671"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC51014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="860" mass="92507" checksum="014A8F52A18DD5ED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W7A085</accession>
    <name>W7A085_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pre-mRNA-processing protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_84707</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SNW family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC49431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685957.1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_84707"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006601_2_0_1"/>
    <dbReference type="OrthoDB" id="666364at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017862">
        <property type="entry name" value="SKI-int_prot_SKIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004015">
        <property type="entry name" value="SKI-int_prot_SKIP_SNW-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12096">
        <property type="entry name" value="NUCLEAR PROTEIN SKIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02731">
        <property type="entry name" value="SKIP_SNW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SKI-interacting protein SKIP SNW" evidence="5">
        <location>
            <begin position="184"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="207"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="318"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="492"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="360"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="521"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="553" mass="62693" checksum="FE06FBC114D82B4C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0X9</accession>
    <name>W7A0X9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_83808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="105" mass="11257" checksum="5B0498DBBA485ED1" modified="2014-04-16" version="1" fragment="single">PPPPVLCTSRRCAFVSFLIQKQGVTSADLTSPSRPCIGPGVAMTDWAVLPCLLARLLARHAPPKLPPSPITVPECPTRSYSHSHMSLTTTPWSRPAPIVALLSHV</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            <end position="336"/>
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    </feature>
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            <begin position="326"/>
            <end position="336"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
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            <position position="1"/>
        </location>
    </feature>
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        <source>
            <dbReference type="EMBL" id="EUC50871.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="67" mass="7425" checksum="BA07903C96789668" modified="2014-04-16" version="1" fragment="single">FVAWIQNAWASSCSLRVLSPGCSGGHRGGLRSCRFIWQRLFCPSCWKMKLKIPINVGAQLICLLSTA</sequence>
</entry>
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    <accession>W6YKJ8</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
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                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
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        </location>
    </feature>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="73" mass="7722" checksum="AFF6AB7330725E7E" modified="2014-04-16" version="1" fragment="single">MHSSEVDLRNTNDMTALMLASCSGHIDVARLLLATGSVSVQTKNAKGFSSLSLANENGHLAVVSLLHEYVASH</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964260">
        <property type="protein sequence ID" value="EUC39757.1"/>
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        <property type="nucleotide sequence ID" value="XM_007695539.1"/>
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    <dbReference type="GeneID" id="19124336"/>
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    <dbReference type="HOGENOM" id="CLU_049466_0_0_1"/>
    <dbReference type="OrthoDB" id="3801492at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="299" mass="34380" checksum="E8D26922770FFF14" modified="2014-04-16" version="1" fragment="single">LQIHLFILRCQVLQSMLDILERKPRTDEVKSNIHIHYDNIYRFASKAGKLAEGFDDTTLQARSEYWTGRGCGGLGDWQSAKTHFGNAIKLDTPNSANYHNGFQNRGLRPNERADVRFLLHIATRRYDRWVHKIEEARKTLSELEFEEIDWEKESMKDGYWTPYRDGLKRAIKQQAEIGRKTGRPMNHLLTSEGQEANILSQKEIKMVLRRLAKRDDKALLCRTLNAEEWRYIFRGNAAVGKDNLSANDTGKGETKDCLPDQPVEHSLPPSIHASAQPSPEISRNLCDELEENEYQSGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMK9</accession>
    <name>W6YMK9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ADP-ribosylation factor GTPase-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_9627</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase-activating protein for the ADP ribosylation factor family.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964159">
        <property type="protein sequence ID" value="EUC40512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692971.1">
        <property type="nucleotide sequence ID" value="XM_007694781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMK9"/>
    <dbReference type="STRING" id="930090.W6YMK9"/>
    <dbReference type="GeneID" id="19128815"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9627"/>
    <dbReference type="eggNOG" id="KOG0521">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002728_0_0_1"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07608">
        <property type="entry name" value="BAR_ArfGAP_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000051">
        <property type="entry name" value="ARF GTPase activator (Csx2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000252">
        <property type="entry name" value="ARF GTPase activator (Csx2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000017">
        <property type="entry name" value="ARF GTPase activator (Csx2), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="664"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="8">
        <location>
            <begin position="841"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="245"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="562"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="799"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1020"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1089"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="800"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="829"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1020"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1120"/>
            <end position="1129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1156" mass="127641" checksum="1C9689C496F58CE9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNC7</accession>
    <name>W6YNC7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-tryptophan decarboxylase PsiD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_9351</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964136">
        <property type="protein sequence ID" value="EUC40832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692636.1">
        <property type="nucleotide sequence ID" value="XM_007694446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNC7"/>
    <dbReference type="STRING" id="930090.W6YNC7"/>
    <dbReference type="GeneID" id="19128281"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9351"/>
    <dbReference type="eggNOG" id="KOG2419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033450_1_0_1"/>
    <dbReference type="OrthoDB" id="5973539at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022237">
        <property type="entry name" value="PsiD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF9">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G01730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12588">
        <property type="entry name" value="PSDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="L-tryptophan decarboxylase PsiD-like" evidence="4">
        <location>
            <begin position="49"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="448" mass="50775" checksum="2BF9122C3C119BE1" modified="2014-04-16" version="1">MSHQEDTKNAPEEHQMHRTGSWLPSDHRVHRKWLGGIIEKVESNPKDLHPVIQEFKDLIEKNTRIYILVNSMFEEIPVKKPYKRDPSGHRQVRDYHHMLELFNHILTTAPEWSDHDYSVGVVGTPFNAILDWPMGTPSGFAFFLDPEVNKMIKKVLGAWADFLASPDSAYVLDNNQIGWFSEHGIHDLELTANVGRSSHKFDELFQCDPKKKHYGYTSWDHFFTRLFHSDKRPVASPDDNCVIANACESKPYKVGRDVAQRDRFWIKGQPYSLMDMLAMDPLHKQFIGGTIYQAFLSALSYHRWHAPVSGTIKKAYLVEGTYFSEPLFEGLGDPSNKGGISEDGEKTGQGYLTATAIRAIIFIEADNSDLGLVCFMGIGMTEVSTCEITVKEGERVEKGDQIGMFHYGGSTHCLIFRKGVELEGFPDTQDVEHNVPVRSKLAVVKKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNH7</accession>
    <name>W6YNH7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_107576</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964132">
        <property type="protein sequence ID" value="EUC40902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692585.1">
        <property type="nucleotide sequence ID" value="XM_007694395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNH7"/>
    <dbReference type="STRING" id="930090.W6YNH7"/>
    <dbReference type="GeneID" id="19119077"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107576"/>
    <dbReference type="eggNOG" id="ENOG502QW7R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008109_0_0_1"/>
    <dbReference type="OrthoDB" id="5229455at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF43">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="749" mass="83203" checksum="D61F329E52885011" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNV9</accession>
    <name>W6YNV9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_30082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="KI964121">
        <property type="protein sequence ID" value="EUC41077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692399.1">
        <property type="nucleotide sequence ID" value="XM_007694209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNV9"/>
    <dbReference type="STRING" id="930090.W6YNV9"/>
    <dbReference type="GeneID" id="19121613"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30082"/>
    <dbReference type="eggNOG" id="KOG1065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_7_2_1"/>
    <dbReference type="OrthoDB" id="10070917at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
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        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF120">
        <property type="entry name" value="HETEROGLYCAN GLUCOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="6">
        <location>
            <begin position="351"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="7">
        <location>
            <begin position="789"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1097" mass="125721" checksum="C0E03DA378E7F726" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNW7</accession>
    <name>W6YNW7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_107117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964121">
        <property type="protein sequence ID" value="EUC41087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692409.1">
        <property type="nucleotide sequence ID" value="XM_007694219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNW7"/>
    <dbReference type="GeneID" id="19118985"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107117"/>
    <dbReference type="HOGENOM" id="CLU_2711490_0_0_1"/>
    <dbReference type="OrthoDB" id="2744543at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="73" mass="8305" checksum="16121F31191C15AE" modified="2014-04-16" version="1" fragment="single">FTNEHARYVYVSLVVDPLGQRLYPNYSPENVRLSVGIFCCPRSEDFEVKKAREAKQETTATRYAGGLARGCFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPC1</accession>
    <name>W6YPC1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_9035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Han J."/>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000082">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="96"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="538" mass="59387" checksum="9EE9F5BAE5D0883F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT49</accession>
    <name>W6YT49_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_75760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964145">
        <property type="protein sequence ID" value="EUC40698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692781.1">
        <property type="nucleotide sequence ID" value="XM_007694591.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT49"/>
    <dbReference type="GeneID" id="19125324"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_75760"/>
    <dbReference type="HOGENOM" id="CLU_158084_0_0_1"/>
    <dbReference type="OrthoDB" id="3666223at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="95" mass="10793" checksum="C996B5C48E51FF3D" modified="2014-04-16" version="1" fragment="single">AVLKQNLPVVELLLEAGADPRLPSRNGSSPIDSLEAWFKQYEIHGNTWAAEDLELRPFFEKALEAMKKARDELDGEFCTDALLWAHYLFANSRCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT73</accession>
    <name>W6YT73_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_30306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964138">
        <property type="protein sequence ID" value="EUC40795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692675.1">
        <property type="nucleotide sequence ID" value="XM_007694485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT73"/>
    <dbReference type="GeneID" id="19121658"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30306"/>
    <dbReference type="HOGENOM" id="CLU_741832_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="373" mass="40392" checksum="6FB408D01BF3B57E" modified="2014-04-16" version="1">MEATTPPAWKPSWNGRRSGPWASQPMRGLSRRLGGGLGGGGGERDREGLALGAWWARWAEAMEATTTSPAPKQWQDHARPFTHPLVPSQPIRSTAERQTWPFKLHFSHVKPLTAEAARRASGSISCAANVGEDGLADTIGPVRLDHRRLSRTSPSRRFYHAAHLGLAGGFITLHPLHSIARCYFVPPVAPAPRPAQLFLPPLCRGWMNGWMDGWMDGWMDGQHHRRCQPTTHARWPSSIDRTCRGEHPTTYDGIAIPACHALARLAPHSTHTLLAGCDLLPMLAPRASVPIAMPIHPIHSPPCRRRALAVGRVGRKKNGTGGDVQLTAHDNVAPWAVAVFVATGRRPCPAASTAPAGRAMHASCSCIMADVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTB0</accession>
    <name>W6YTB0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Ceramide very long chain fatty acid hydroxylase</fullName>
            <ecNumber evidence="18">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">COCMIDRAFT_7790</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="20">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18 19">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="18 19">Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the sterol desaturase family. SCS7 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="18"/>
    <dbReference type="EMBL" id="KI964053">
        <property type="protein sequence ID" value="EUC42667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690800.1">
        <property type="nucleotide sequence ID" value="XM_007692610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTB0"/>
    <dbReference type="STRING" id="930090.W6YTB0"/>
    <dbReference type="GeneID" id="19125394"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7790"/>
    <dbReference type="eggNOG" id="KOG0539">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034756_0_1_1"/>
    <dbReference type="OrthoDB" id="2204368at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080132">
        <property type="term" value="F:fatty acid 2-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000007">
        <property type="entry name" value="Sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
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    </dbReference>
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        <property type="entry name" value="Scs7"/>
    </dbReference>
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        <property type="entry name" value="FATTY ACID 2-HYDROXYLASE"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IPC-B_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17 18" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="10 18" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 20" id="KW-0349">Heme</keyword>
    <keyword evidence="14 18 20" id="KW-0408">Iron</keyword>
    <keyword evidence="5 18" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="16 18 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 18 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11 19" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="22">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
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        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>heme</name>
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        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
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        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>heme</name>
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        </ligand>
        <ligandPart>
            <name>Fe</name>
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        </ligandPart>
    </feature>
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        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
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            <label>1</label>
        </ligand>
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    <feature type="binding site" evidence="19">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <location>
            <position position="357"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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            <position position="358"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
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            <dbReference type="ARBA" id="ARBA00004991"/>
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    </evidence>
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        <source>
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        </source>
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        <source>
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        </source>
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        </source>
    </evidence>
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        </source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="392" mass="44476" checksum="CC01EFE30C194BDC" modified="2014-04-16" version="1">MPGRTLPTIPTAEVRAHNTDKSCYVTIGTKVYDVTDFLDGHPGGPELILEYAGKDVEAILKDEISHAHSNSAYEILEENLVGFVATESVINGAVKSSTPADIIPLPPSQAGTQELKTMSQDGKPLYAATGMSSEDDLSKETDPNKDYKEHKFLDLNRPLFMQVWNGGFSKQFYLEQVHRPRHYKGGDSAPLFGNFLEPLSKTPWWVVPTIWWPCVAYGTAVAYGGLRSVPELAGYWIFGLCFWTIIEYVLHRGLFHLDDHLPDNRVAITLHFILHGIHHYLPMDKYRLVMPPTLFTALATPFWSVAHGTIFWNWHAAVAAFCGGVFGYTCYDMTHYFLHHQKLPSYYQQLKKYHLKHHFADYQNGFGVTSRFWDWVFGTELDMGPTKVIKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU67</accession>
    <name>W6YU67_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_107135</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="10"/>
            <end position="293"/>
        </location>
    </feature>
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    </evidence>
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    </evidence>
    <sequence length="294" mass="32368" checksum="A35951668DE71C04" modified="2014-04-16" version="1">MSIRSITGTWDCHIHCFEPDKFPFKTPRAYTPCPAPVDLLLQNLLTNNVMIVQASVEASMDGLLATLEYCGKRPDHFSGLVRGTVLADASTPLSSLTDSQIERMHLLGVRCIRLHGVYGGLGQDPAWVQRQMTALAQVSQVRNLGWKISAQLPLATWSQLKHFILTDKHLAGLPIVADHIACATPSDHGSLALHDFVELLQSGRVYVKISALHRRSPRNIHAMRDIISLLARSAPQALLWGSDWPHVDASQNDFEAGPLEGADPSAELAAVQSWLSTEQFQDMLVNNPCRLFGN</sequence>
</entry>
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    <name>W6YVH1_COCMI</name>
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        <recommendedName>
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        <name evidence="2" type="ORF">COCMIDRAFT_111386</name>
    </gene>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007695786.1"/>
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    <dbReference type="eggNOG" id="ENOG502S3XQ">
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    </dbReference>
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    <dbReference type="OrthoDB" id="3701758at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051289">
        <property type="entry name" value="LAGLIDADG_Endonuclease"/>
    </dbReference>
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        <property type="entry name" value="INTRON-ENCODED ENDONUCLEASE AI3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181:SF2">
        <property type="entry name" value="INTRON-ENCODED ENDONUCLEASE AI3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LAGLIDADG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homing endonuclease LAGLIDADG" evidence="1">
        <location>
            <begin position="48"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="185" mass="21033" checksum="8B6EBF3A68975C0D" modified="2014-04-16" version="1">MEFHVLNFSILPVIGTVHKNALKKGKNNSRLENQEYLNIPSSFLAFFAGLVDGDGYIQITNTTKGFITMKLVISLHLEDLSTLEYINSVLKVGKLNIYRDNRSPTCSFFVKANNDGCFQLKQRIHKNLFEAFKLVFDTNRKIETEKGLYNQFGVSSKSDIQKVINFFSFSGLHPLVGLKGIQYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVR9</accession>
    <name>W6YVR9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_7071</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964027">
        <property type="protein sequence ID" value="EUC43512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689965.1">
        <property type="nucleotide sequence ID" value="XM_007691775.1"/>
    </dbReference>
    <dbReference type="GeneID" id="19125168"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7071"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001471">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF15">
        <property type="entry name" value="ALPHA-FACTOR-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="795"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="839"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="916"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="941"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1019"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1062"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="50"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="377"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="798"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1117"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="634"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="722"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="645"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="722"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC43512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1417" mass="156542" checksum="305DB1029CEE86AA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVY2</accession>
    <name>W6YVY2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964091">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693614.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19123832"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40186"/>
    <dbReference type="HOGENOM" id="CLU_095732_0_0_1"/>
    <dbReference type="OrthoDB" id="10512384at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="254" mass="27086" checksum="8F4875078FB08946" modified="2014-04-16" version="1">MHPLVAIANDSQAASLRATLNGDPPVPGFLAPSACRRHHRPSGPRHPSLHSRSTLQLQQPHPPARHVHGVRVRTPIDGAVLCDSMLPCVKPSRAPSGACSDYLRRPAPQQRPAWAKPSQRRRAVRRGSRWLHASKARGVRGDPGCATIEMGSIGRSTAAVRPFRLASAAALARPPTSPPQLTAPRHASFFGPTADTRLHRASCLPLSTAARLPLPCPLLQPVQCILSRGCAPFATSGPLASIHAAPIGQKRSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW94</accession>
    <name>W6YW94_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_40034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964084">
        <property type="protein sequence ID" value="EUC41825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691645.1">
        <property type="nucleotide sequence ID" value="XM_007693455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW94"/>
    <dbReference type="GeneID" id="19123795"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40034"/>
    <dbReference type="eggNOG" id="ENOG502SS2T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057547_3_1_1"/>
    <dbReference type="OrthoDB" id="4500473at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="238" mass="25895" checksum="A40A0AA86C9C4A23" modified="2014-04-16" version="1">MPGTWFLPSDFTFTTEGPLRLGMVIPHWSRPTTVLAEMGSGNNSAVTLPTIKITVERNRAFNRSKSRSDSVGMWAKFEGLASVLANTETGKSRITDYMYVVTGLRIATSSFTVTEEDSSNFSIEAEGSGPASGTTPVEVGGKIKHQSGKTAMNSYDTAPGIVFAYQLNVIRTRRAGVETELFSHKSSFLTGEGGKKEDPLVIVDATKEEIDEDLEEDVEYDSAEVGEDETCIYLLPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWB3</accession>
    <name>W6YWB3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_10155</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964240">
        <property type="protein sequence ID" value="EUC39829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693647.1">
        <property type="nucleotide sequence ID" value="XM_007695457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWB3"/>
    <dbReference type="STRING" id="930090.W6YWB3"/>
    <dbReference type="GeneID" id="19117888"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10155"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_3_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF138">
        <property type="entry name" value="DEHYDROGENASE PKFF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="569"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="613"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="614"/>
            <end position="615"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC39829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="633" mass="67882" checksum="C11D410171FC7FA5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWG2</accession>
    <name>W6YWG2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964234">
        <property type="protein sequence ID" value="EUC39864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693613.1">
        <property type="nucleotide sequence ID" value="XM_007695423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWG2"/>
    <dbReference type="STRING" id="930090.W6YWG2"/>
    <dbReference type="GeneID" id="19119584"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110339"/>
    <dbReference type="eggNOG" id="KOG1549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_2_1"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586:SF21">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE (PLP)-DEPENDENT ASPARTATE AMINOTRANSFERASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="20"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="394" mass="43501" checksum="849AE52AA64C37CE" modified="2014-04-16" version="1">MTFDITKARSRFPALQQDQVFLDNAGGSQALGEVIDSISQYLSKTNVQLGASYHTGTQSNTKYEEGYQAAAKYINAGRDEIVLGSSTTQLFVNLGSTLQFPAGSEIILSKMEHETNVKAWLLMADRLGLTVKWWASSKEDGLKLTAENLKPLLSDKVKFVACTHVSNILGTIHDVKSIADAVHEVGALFCVDGVSYAPHRAVDVKAFGVDFYAFSWYKVYGPHIAVLYASEPGQKVMKPMAHYFNPTKTLEDKIGFAGSNYECVQSIPQITSYLSGAFPAIAEHEGKLQTILLDFLNSRPDITVLGSTSTDSKVRVPTISFVVKGMNSKQVVAEAEKISNYGFRWGHFYSKRLCDEVLEIDPEGYVTRVSMVHYNTEEEIKGLVEVLKKVLPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ09</accession>
    <name>W6YZ09_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_51796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688906.1">
        <property type="nucleotide sequence ID" value="XM_007690716.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ09"/>
    <dbReference type="STRING" id="930090.W6YZ09"/>
    <dbReference type="GeneID" id="19124521"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_51796"/>
    <dbReference type="eggNOG" id="KOG2919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022731_0_2_1"/>
    <dbReference type="OrthoDB" id="239865at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051150">
        <property type="entry name" value="SWT21/TCAB1_mRNA_Telomere"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211:SF0">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="49093" checksum="11448D055318A5BF" modified="2014-04-16" version="1" fragment="single">EEVENDAEDENDAVEPSSPSSSSISSSSSSPPSLTQRLRNTHHTSCVQEAQLSPDGSCIFTSDYNRSFSVYPVSNDIGSHTSAQSLTPYASLHSPNPIWAFAANPLFNLQDANSTTVLVSRRDSYITLHNALWDISRTYANEENPPPTPGPVNISTSLASYKLINNLTEAVTAPISLTYSHDGAHFFGGTQDKIVIFDLQETDKPIHTIATIPARRNKLKGGGRGFKGYISALSLSPPSPPSRDGLLAAGSRTRHIGIYDPTSGTEVTSFALPGTSSGVKSRNENLKDVMGDGVSSLKWSPCGNYLYVAERNADVLLIYDVRSFSLALGYCAGRRALTKQKLGFDVWNAGQSPYDVEGFSHEVWAGGTDGKVRVWRDAYAKEGTVLPDEVISVGHEDEPVVASLVYPTGSLVVAATGVVRVEDEEEEQRGVQRGGGGGGGVRPRFREWGNVDILALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZX7</accession>
    <name>W6YZX7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_9159</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964121">
        <property type="protein sequence ID" value="EUC41084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694205.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_9159"/>
    <dbReference type="eggNOG" id="ENOG502RZKF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_3_0_1"/>
    <dbReference type="OrthoDB" id="428768at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
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        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF8">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="25"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC41084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="176" mass="19510" checksum="8F6B31212A44CA53" modified="2014-04-16" version="1">MTSFNDQGFPIVNLSNDGWSTENEATATCFCGSVQLVLPLQKPGLINRHICHCVDCRKIGSAFYQSNITVADSHLKHVRGEDNLTIFGETETIRANARMTNYFCKTCGTLMYRRGARFPGMSILRTGTVDDLSLAETKLRPQVEQFIERRVAWSVPIEGAAQATGMHQPSDIEGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z055</accession>
    <name>W6Z055_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exocyst complex component Sec3 PIP2-binding N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_5696</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963992">
        <property type="protein sequence ID" value="EUC45027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690227.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z055"/>
    <dbReference type="GeneID" id="19124707"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5696"/>
    <dbReference type="eggNOG" id="KOG2148">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002075_1_0_1"/>
    <dbReference type="OrthoDB" id="27109at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13315">
        <property type="entry name" value="PH_Sec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.90:FF:000003">
        <property type="entry name" value="Exocyst complex component Sec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028258">
        <property type="entry name" value="Sec3-PIP2_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048628">
        <property type="entry name" value="Sec3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019160">
        <property type="entry name" value="Sec3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092:SF14">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092">
        <property type="entry name" value="SEC3/SYNTAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15277">
        <property type="entry name" value="Sec3-PIP2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20654">
        <property type="entry name" value="Sec3_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09763">
        <property type="entry name" value="Sec3_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01313">
        <property type="entry name" value="Sec3-PIP2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec3 PIP2-binding N-terminal" evidence="7">
        <location>
            <begin position="98"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="219"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="659"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="850"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="435"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="497"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="532"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="659"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="696"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1579" mass="174589" checksum="E676EF3806B35511" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0K6</accession>
    <name>W6Z0K6_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_38814</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0K6"/>
    <dbReference type="STRING" id="930090.W6Z0K6"/>
    <dbReference type="GeneID" id="19123556"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38814"/>
    <dbReference type="HOGENOM" id="CLU_076127_0_0_1"/>
    <dbReference type="OrthoDB" id="3642826at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="227" mass="23887" checksum="58B3497FC399A33B" modified="2014-04-16" version="1">MAAESLDMVVLCPFSIRITEFNPYHTSADLTSGNHLHQHSARRCDPNGHHESAEPNFSERLDPAPLITQAPPLATVSAGSAIVVVQQELDSDNFVIEGTHTVVPGKPITTEVIVGTTVIFLQPNYPQATYGPPLVPPPPILTAGTTTVMPVTALVINRKTSSVVPVTGSIYTAVVPAALTFREQSYTVHRAGHIIMGQEATLTPGGNPVTIDGTTLSLEPSGSAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0N4</accession>
    <name>W6Z0N4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_95948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688217.1">
        <property type="nucleotide sequence ID" value="XM_007690027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0N4"/>
    <dbReference type="STRING" id="930090.W6Z0N4"/>
    <dbReference type="GeneID" id="19128753"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95948"/>
    <dbReference type="eggNOG" id="KOG0294">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030368_0_0_1"/>
    <dbReference type="OrthoDB" id="308449at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051959">
        <property type="entry name" value="PAK1-Kinase_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675:SF1">
        <property type="entry name" value="P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675">
        <property type="entry name" value="PAK1 INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="402"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="508" mass="54587" checksum="409E5A58A32C7EBF" modified="2014-04-16" version="1">MAKRKRENGESAAAAKALKSRKNEVASKFQKLAVEDATEVQTAVTENGNTIPDTTTIQVITGSYERVLHGFAASIPSTLLTGQDDASAPESDAPKVDFTDTFLFNAHASAIRCMALSPLSDETSKITLATGSTDERINLYSISTAPPSKNRPKLPSLNDGSITENPKNKELGSLLHHSSNITALYFPTRSKLLSSAEDSTIAITRTRDWTALSTIKAPIPKPQGRPSGDTAGPGEVPSGINDFAVHPSMKLMLSVGKGEKCMRLWNLVTGKKAGVLNFDRTILGAVGEGRFSSGEARRVLWDPEGEEFAVGFDRALVVFTIDSKPKAKIAPEPRSKIHQIMYLPKTMQRESILLVSTEDGRVLVYDTSKTIPQQDDEKAGKQNQNIPDAKLLAQIGGPAAGLTGRVKDFEILPLSQSTCVIVTACSDGTVRLWALDTSDLDAKSQQDGESKKGFSAPQVAKLLASYSTGTRITCLKAFPMTGTPDDADDDDEEEEGKKPQDSSSDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0Z7</accession>
    <name>W6Z0Z7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963984">
        <property type="protein sequence ID" value="EUC45432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688043.1">
        <property type="nucleotide sequence ID" value="XM_007689853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0Z7"/>
    <dbReference type="GeneID" id="19128676"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95525"/>
    <dbReference type="eggNOG" id="ENOG502S621">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047721_1_0_1"/>
    <dbReference type="OrthoDB" id="5370011at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="375" mass="42300" checksum="F976AF7138B5E177" modified="2014-04-16" version="1">MSTPPNPPAQDKAKTGLGKYVKRMSTVFKRDRSSKSQPPASAPDAPSSSSAAAAQQPQPPPPQPQQQQKLQEQQPAPASPPPQQQQQQQQQQQQEIPSIDNEASKSLDRNAMQQERAHALFAKYGLTLESHEWIAAPGPMPPLQRVEKPIRMRVHRTCHRCGTLYGADRTCVQCEHRRCKKCPRFPKKKTPEEKQAEKDAPDQPKRKRMLTIRTRAGDELVYQPTKQRIRRTCHKCSTVFVPAQAVICQNCHHARCTKCPREPAKLTKWPAGYPGDAEADSETEVDRQLETFRRTWRKPRTRVRWQCEKCNSLFQNHQPQCPGCGHERCDQCTRSPVKKAKKSDQFDAQVVAAVEAKLRAMGVDDEGPSSAAEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1C1</accession>
    <name>W6Z1C1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_95266</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687951.1">
        <property type="nucleotide sequence ID" value="XM_007689761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1C1"/>
    <dbReference type="STRING" id="930090.W6Z1C1"/>
    <dbReference type="GeneID" id="19128619"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95266"/>
    <dbReference type="eggNOG" id="KOG2101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002131_1_0_1"/>
    <dbReference type="OrthoDB" id="120967at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="Wang R."/>
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                <person name="Salamov A."/>
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                <person name="Han J."/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        </source>
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        </source>
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        </source>
    </evidence>
    <sequence length="526" mass="55257" checksum="4CD449843545A1D4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3P8</accession>
    <name>W6Z3P8_COCMI</name>
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        <submittedName>
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            <taxon>Pleosporales</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
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            <end position="236"/>
        </location>
    </feature>
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        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="236" mass="25336" checksum="8301473CCF89E7CF" modified="2014-04-16" version="1">MPRSSASSPYLHFEGEEDDRETDHDTPEVVINAATQIRGHGNIISIAQMDSVRIANLITSLLNCGDKIPVDDATRPLTPPSPVPLATAQAQRTTRTQVRGVHRYPNINITVNCGATVLGDRNIVGPGLGDIARQMQMAQRNQAAALQAHQQLQQRQAAAAAAVAAEEQKTASPPLQRSGSMYQTATSPSQYCRQVPLSHGVATPPMSRSSSLHSDGESRKRKGADVCEAAEAKRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UBX domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
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    </dbReference>
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        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
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    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SEP" evidence="4">
        <location>
            <begin position="233"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="3">
        <location>
            <begin position="353"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="315"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="45705" checksum="853792CF93FE9F27" modified="2014-04-16" version="1">MSEAATDRDAQVAQLASLTGLDAATAERYLNAANGDLTLAASLFFDQTAEQQEADSEPDVDMAGDDDSNTNPSQNPPPPSGGGRTLGGDYVPSSAPAASSSSSSQRPAGRGQPTQRGVAGARTLRDLQSSGGGQGQAHDDEDDEHSPEDDSQDFFAGGEKSGLAVQNPNQSNPRDQINNILKRARQNAPRPGGDDEQPASSHFRGAGTTLGGDDAPSRIVPDPNANMPAPPPRAHRELHLWRDGFSVDDGDLFRYDDPANARTLEMINTGHAPLHILNVEHGQEVDVEVHAHKDEDYKKPKKKYVPFSGSGNRLGSPTPGSSSTAATIPAAGSSSTGASTSGGSAQPSVEVDSSIPTLTLQVRLGDGTRLTSRFNTTHTIGDVYDFVTRASTASQGREWALMTTFPSKELTDKGQVLGDIAEFKRGGVVVQKWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z569</accession>
    <name>W6Z569_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase C14 caspase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_96320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963990">
        <property type="protein sequence ID" value="EUC45130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688353.1">
        <property type="nucleotide sequence ID" value="XM_007690163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z569"/>
    <dbReference type="GeneID" id="19128831"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96320"/>
    <dbReference type="eggNOG" id="KOG1546">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029389_3_0_1"/>
    <dbReference type="OrthoDB" id="3223806at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="319" mass="35617" checksum="A06617593955C25B" modified="2014-04-16" version="1">MAYQRKKSLLIGINYVGSSHELRGCHADVDNMAEFLYYRGYNNSPKDRVILTDRPEVPPDSPYYPTGHNILAAMDWLVSEPGCTLFLHYSGHGGQVADVDGNRTTGLDTSLVPIDFEQRGQISSTILHQHLVTRMARDCTLFVIMDCCHSGSALELPYVYRSDSDGQISLMDNLKTGLHLAEEARDIISGGFTFDKVGEAQQLLAGASSFFKGLRHMGEEQEEGLEHGEFADQYGHERKMVTMFSGCKDEQTSADAHIEGRATGAMTWAFLEMMKTTERPSYAETLKHTRKLLDESNYTQIPQLSCGLDIDLDEMTLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z667</accession>
    <name>W6Z667_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">2-oxoglutarate reductase</fullName>
            <ecNumber evidence="4">1.1.1.399</ecNumber>
            <ecNumber evidence="5">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_90804</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.399"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.399" evidence="4"/>
    <dbReference type="EC" id="1.1.1.95" evidence="5"/>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686276.1">
        <property type="nucleotide sequence ID" value="XM_007688086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z667"/>
    <dbReference type="STRING" id="930090.W6Z667"/>
    <dbReference type="GeneID" id="19127757"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90804"/>
    <dbReference type="eggNOG" id="KOG0068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_9_2_1"/>
    <dbReference type="OrthoDB" id="1621027at2759"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061759">
        <property type="term" value="F:2-oxoglutarate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04901">
        <property type="entry name" value="ACT_3PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12176">
        <property type="entry name" value="PGDH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000036">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000041">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050857">
        <property type="entry name" value="D-2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008759">
        <property type="entry name" value="PRK11790.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42789">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42789:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="16">
        <location>
            <begin position="415"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC47232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="485" mass="52508" checksum="B8E4784D42302A02" modified="2014-04-16" version="1">MTPAQDIAGSISQISRSVSNSLNISTSPTLSFHSPPSTFRQPPSASSRDGRTPNLPGTSHAQQLAKQLKPFDTKDIKVLLLENVNEAGVDILRGQGYQVEAIKASLGEDELIEKIRDIQVIGIRSKTKLTKKVLEAAKNLIVIGCFCIGTNQVDLQTAASKGIAVFNSPFSNSRSVAELVISEIIALARQLTDRSMELHNGTWNKVSKGCWEIRGKTLGIVGYGHIGSQLSVLAESMGMSVIYYDVLTTMGLGTARQVPSLDDLLAQADFVSLHVPATAETKNMIGKEQFAKMKDGSYLINNARGTVIDIAALIEASRSGKLAGAAIDVFPNEPAGNGDYFSNELNTWTKDLVGLKNIILTPHIGGSTEEAQSAIGVEVSTALVRYVNEGTTLGAVNMPEVNLRSLTLDQPDCMRVIYIHKNVPGVLRQVNGILLHHNIEKQMSDSRGDVAYLMADISEVKESEIRDIFTSLEELSSCIRTRVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z690</accession>
    <name>W6Z690_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">beta-glucosidase</fullName>
            <ecNumber evidence="4 11">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_101770</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4 11"/>
    <dbReference type="EMBL" id="KI964040">
        <property type="protein sequence ID" value="EUC43069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690394.1">
        <property type="nucleotide sequence ID" value="XM_007692204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z690"/>
    <dbReference type="STRING" id="930090.W6Z690"/>
    <dbReference type="GeneID" id="19117928"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101770"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_4_0_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000006">
        <property type="entry name" value="Beta-glucosidase H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF3">
        <property type="entry name" value="BETA-GLUCOSIDASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="12">
        <location>
            <begin position="399"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC43069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="835" mass="90721" checksum="56D9DB2EA181609F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6G6</accession>
    <name>W6Z6G6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963985">
        <property type="protein sequence ID" value="EUC45398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688089.1">
        <property type="nucleotide sequence ID" value="XM_007689899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6G6"/>
    <dbReference type="GeneID" id="19123131"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36875"/>
    <dbReference type="HOGENOM" id="CLU_719940_0_0_1"/>
    <dbReference type="OrthoDB" id="3800314at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="428" mass="48273" checksum="B884BAFC1398BB20" modified="2014-04-16" version="1">MQRPTGTKAPKELDLEWAARELVPFLEWAFGEQYGRSQRTKAYWVEKVLWAKDRIDSVTYYIDFASTIDTLRLYLVNKAHLTPKELLEFSVVAVKGESLCIRIFVHYAMRHCNYDLYSLGTHQSPYFPRSLTVPIPKHPHIKLPESEYEAIMAEIQKQLNKNSCTTTGREGSGREGSEHRVGGELVRNRFSNAGSDASSTQYSSALSSNSSQTQSKPIDRYLRAPGTLPKYNTSSVVLQESHIPSATSQESQVSSTAPQDWQNHPSSSQQGYLPPHGPYPGPRGVHGPSVPATTQTSMSQYHQQYPPSMQSQSLYPPLPTNWPYNSPRTDHMMSYYPSWTNPIIPEMSNPYVAWPPPAAIANQHMTHNFNPGQEQPTLAHTTAHTYVPHPETKEFIHEAARKSGLLQEHHSRTNVYNAAHMVSCMAPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6J1</accession>
    <name>W6Z6J1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_5340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="OrthoDB" id="3904016at2759"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="291" mass="32367" checksum="A3BF0BF0FFE5F42E" modified="2014-04-16" version="1">MKCYADSCQPWMASVTRGNYFFPIEDTFPYSVQVSRLELEKDLLENGLANCVTYLQALRKKQSRNERRLAADSSLPVRKKKKIRQSMRHLEKEIQNRERDEQAFLNNLQACKANIYLAETVSSPSTTVSSTIPDLASVSTLCSYPEEPEARDGQWNGWVDKMASSLFQKDCSNSTSIDDIAPDDHLGADGSDLAIIKSTVCAQYVAQTGATWLLPMTCTSKQFVFSPEAALFEPQNTYKDQDMQLDQQFAELRLASSIAATTLDGGGLGGSMDTCRLTKFVTAQPNPKKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6K8</accession>
    <name>W6Z6K8_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28360</name>
    </gene>
    <organism evidence="2 3">
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            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964038">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6K8"/>
    <dbReference type="GeneID" id="19121291"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28360"/>
    <dbReference type="HOGENOM" id="CLU_591817_0_0_1"/>
    <dbReference type="OrthoDB" id="10578305at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="462" mass="51446" checksum="A30A6F2B5D79090E" modified="2014-04-16" version="1">MCMYSMSRRQEYAPKRQLGGLAWDARVCQEICLKGIVTGIGSGKPGYQWPRGHRPTSHHGPVCRSSYAWDQDDTTLEYPASLKTFTRLINGDRATAVSRPSRHRRRRRKKEKGSDSLGRHPRLGCCTLLSVPWNCYRRNWMLSCRGGHNKPRVMCLAANASGRGENESFWRRTRQHTAPSHSASNLSCMCAQPAHRHILHSAAPWCPQAPCLHMGMSDTFCLWPAACHGHSYLHPLRRCKEFAAPQAYPALACCFCTWAVKVKVWSRAPANCRHALALLTSPVSTQHSTQPLQLRVCVLLLCGCAYHHARPPLPSPPPPSPWTHKAGTGPESYGRRCVRVLLPPPPLLLGSCSCCTYLYSPTTHRRRLRHASTFAQLQLSGIHVLRTPPAPPSAHPSIHPREVYFGHVDVGYMALAPHPKLPSTYQEPLCSAVVCTLYFPRLPSPEVSPAVPTVCTCYAHPP</sequence>
</entry>
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    <name>W6Z7F8_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">SUI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_36580</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7F8"/>
    <dbReference type="STRING" id="930090.W6Z7F8"/>
    <dbReference type="GeneID" id="19123061"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36580"/>
    <dbReference type="eggNOG" id="KOG2522">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012487_1_1_1"/>
    <dbReference type="OrthoDB" id="199771at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11608">
        <property type="entry name" value="eIF2D_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21156">
        <property type="entry name" value="PUA_eIF2d-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.780.10:FF:000008">
        <property type="entry name" value="eukaryotic translation initiation factor 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039757">
        <property type="entry name" value="EIF2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039759">
        <property type="entry name" value="eIF2D_SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041366">
        <property type="entry name" value="Pre-PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
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        <property type="entry name" value="PUA_eIF2d-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
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    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058886">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
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    </dbReference>
    <dbReference type="InterPro" id="IPR057429">
        <property type="entry name" value="WH_eIF2D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12217">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2D"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR12217:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17832">
        <property type="entry name" value="Pre-PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26292">
        <property type="entry name" value="PUA_elF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SWIB_eIF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25304">
        <property type="entry name" value="WHD_eIF2D"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="2">
        <location>
            <begin position="543"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="636" mass="69000" checksum="EACF7F9EAF427964" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7U1</accession>
    <name>W6Z7U1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_10226</name>
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    <organism evidence="3 4">
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964262">
        <property type="protein sequence ID" value="EUC39746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693736.1">
        <property type="nucleotide sequence ID" value="XM_007695546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7U1"/>
    <dbReference type="STRING" id="930090.W6Z7U1"/>
    <dbReference type="GeneID" id="19118044"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10226"/>
    <dbReference type="eggNOG" id="ENOG502SJFP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021439_0_0_1"/>
    <dbReference type="OrthoDB" id="5418336at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="75"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="430" mass="48380" checksum="ABE294379B2018BA" modified="2014-04-16" version="1">MSGDPRPHQDIRYVSVLQGSRAYIGTFSNCDFGNTEESQNASKQAAIACRSALFLTDPHVDRESVISAKGTRVAGTCEWITHNETYRAWLDSDGDGNGGDSKDNNTRLLWITGGPGKGKTMMSIFLTEELEEYTAYKDNTDLVFFFCSAEDKRRNTATAVLRGLVHQMITKRPQLVKHALPYFETPERTQQTLLSFETLWLIFSKLIADTKLGTMFCVLDGLDECEESTLKVLLPRLISLLTIENSPSTKGTFKLAIVSRDLLRLRGCTMRVRLDPDNDEKVASDIELFVSTRVQELSKIEDFNEDFRASVQTALLQRAEGTFLWVGFAMYELSQKRTCSEIWEALENLPSGLPAIYSRMLLQVPARQREQSQAILRWVTVAARPLQLQELVAAVGIQGTRMTVEQAARDAVARCRPLLKIQKQEVSLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7X8</accession>
    <name>W6Z7X8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_93693</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963971">
        <property type="protein sequence ID" value="EUC46110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687356.1">
        <property type="nucleotide sequence ID" value="XM_007689166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7X8"/>
    <dbReference type="STRING" id="930090.W6Z7X8"/>
    <dbReference type="GeneID" id="19128308"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93693"/>
    <dbReference type="eggNOG" id="ENOG502SASX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125562_1_0_1"/>
    <dbReference type="OrthoDB" id="2017497at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032126">
        <property type="term" value="C:eisosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070941">
        <property type="term" value="P:eisosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052649">
        <property type="entry name" value="NCE102-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165:SF2">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165">
        <property type="entry name" value="NON-CLASSICAL EXPORT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="7"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="180" mass="19598" checksum="1031566459A3C592" modified="2014-04-16" version="1">MVPSIFNVALRGVQALFGIIILGLSVTLIHGHHWGSLPAGLGYGAFVGGLSFVAAFIGLAATRFDSLGGMFGFVIDSVIALINLAGGVLYAFNLRGVDCKMRAEDPSNVEKMIDNEWLNGGCREYKFCWNGFKYGDESKAIAVYEGHCKEAKADSVFMFLTAIVMLVCALLVWLRMRRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z895</accession>
    <name>W6Z895_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF431-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_99919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964019">
        <property type="protein sequence ID" value="EUC43779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689697.1">
        <property type="nucleotide sequence ID" value="XM_007691507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z895"/>
    <dbReference type="STRING" id="930090.W6Z895"/>
    <dbReference type="GeneID" id="19129566"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99919"/>
    <dbReference type="eggNOG" id="ENOG502RZ65">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080487_0_0_1"/>
    <dbReference type="OrthoDB" id="373498at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035241">
        <property type="term" value="F:protein-arginine omega-N monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18090">
        <property type="entry name" value="Arginine_MT_Sfm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007364">
        <property type="entry name" value="SFM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517:SF1">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04252">
        <property type="entry name" value="SFM1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="22830" checksum="8603154AF8DCA1FE" modified="2014-04-16" version="1">MASTGKTFVVEHLDPELEEWSSLEYSAIAAECHASGAQFLLSSVPTSLTLPANLQGAKGLQVETRGIEEIYADKKDKVCLLDPAASKDLSPEDGDTFDIFLFGGILGDDPPRDRTSELRKKGYQGRRLGPVQMTTDTAVRVTRICVQDKVPVDQIAYIDHPDLKINKNESTQMPFRYVKGNDGQPIMPEGMRDLIVKDSAKSLNDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8M6</accession>
    <name>W6Z8M6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PSP proline-rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_6751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964017">
        <property type="protein sequence ID" value="EUC43889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689595.1">
        <property type="nucleotide sequence ID" value="XM_007691405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8M6"/>
    <dbReference type="STRING" id="930090.W6Z8M6"/>
    <dbReference type="GeneID" id="19125070"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6751"/>
    <dbReference type="eggNOG" id="KOG2330">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014435_1_1_1"/>
    <dbReference type="OrthoDB" id="10260794at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007180">
        <property type="entry name" value="DUF382"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006568">
        <property type="entry name" value="PSP_pro-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052584">
        <property type="entry name" value="U2_snRNP_Complex_Component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785">
        <property type="entry name" value="SPLICING FACTOR 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785:SF6">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04037">
        <property type="entry name" value="DUF382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04046">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00581">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP proline-rich" evidence="2">
        <location>
            <begin position="277"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="569" mass="63944" checksum="6DEB7EAAA8F3245C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8T5</accession>
    <name>W6Z8T5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_92798</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687050.1">
        <property type="nucleotide sequence ID" value="XM_007688860.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z8T5"/>
    <dbReference type="GeneID" id="19128147"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92798"/>
    <dbReference type="eggNOG" id="KOG2102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002333_0_3_1"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048027">
        <property type="term" value="F:mRNA 5'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000900">
        <property type="term" value="F:mRNA regulatory element binding translation repressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060237">
        <property type="term" value="P:regulation of fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903450">
        <property type="term" value="P:regulation of G1 to G0 transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.690:FF:000001">
        <property type="entry name" value="Cell wall biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.700:FF:000002">
        <property type="entry name" value="Cell wall biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000100">
        <property type="entry name" value="Cell wall biogenesis protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041093">
        <property type="entry name" value="Dis3l2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17877">
        <property type="entry name" value="Dis3l2_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="3">
        <location>
            <begin position="741"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="497"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="597"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1183"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="605"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1208"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1240"/>
            <end position="1255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1363" mass="150543" checksum="D7047CB0796AE611" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8U8</accession>
    <name>W6Z8U8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit TIM44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_35926</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim44 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687033.1">
        <property type="nucleotide sequence ID" value="XM_007688843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8U8"/>
    <dbReference type="STRING" id="930090.W6Z8U8"/>
    <dbReference type="GeneID" id="19122899"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35926"/>
    <dbReference type="eggNOG" id="KOG2580">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020932_2_0_1"/>
    <dbReference type="OrthoDB" id="10265990at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.240:FF:000002">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim44-like" evidence="14">
        <location>
            <begin position="393"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="98"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="127"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC46440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="553" mass="61524" checksum="CD4589FD453F86ED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8V1</accession>
    <name>W6Z8V1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_109615</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964196">
        <property type="protein sequence ID" value="EUC40116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693361.1">
        <property type="nucleotide sequence ID" value="XM_007695171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8V1"/>
    <dbReference type="GeneID" id="19119468"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109615"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_2_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF315">
        <property type="entry name" value="TRANSPORTER MCH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="328"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="41755" checksum="907BB0EC44B486B2" modified="2014-04-16" version="1">MATQSDHLSSTGAEEFDDISEHGNRRGQVPPDGGYGWICVAACFTINCFTWGTVSAYGVYLSHYLAEEVFPDASTWDFAFVGGFNYSIAMLIAPGVTILNRRLGMHTTMIIGLIFQTSGFIGASFATRIWQLYICQGFLIGCGISFLYVPSLPILSQWFVRKRSLVNGVSAAGSGVGGAAFAWGTEAIIQRFSIGWALRITGILALAANLAAITAIRDRNHIIQPSQLGFDTTLLRRYDVILLLAWAAISMLGYVVLLFSLSDFALSIGLDRAQATDVVGLLNIGTAVGRPVIGILSDRWSRIDTAGVLTLLCGLSCFAFWLPATTFALTVFFSIVCGAIVGVFWMTIGPLCVEVAGLKNLQSLLSLSWAAVVIPTTGTSYLIYRSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9D8</accession>
    <name>W6Z9D8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acyl-CoA thioesterase II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_92275</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686854.1">
        <property type="nucleotide sequence ID" value="XM_007688664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9D8"/>
    <dbReference type="STRING" id="930090.W6Z9D8"/>
    <dbReference type="GeneID" id="19128044"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92275"/>
    <dbReference type="eggNOG" id="KOG3016">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032690_3_0_1"/>
    <dbReference type="OrthoDB" id="68328at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03444">
        <property type="entry name" value="Thioesterase_II_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03445">
        <property type="entry name" value="Thioesterase_II_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000074">
        <property type="entry name" value="Acyl-CoA thioesterase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066:SF34">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="3">
        <location>
            <begin position="39"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="4">
        <location>
            <begin position="157"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="41943" checksum="285A6090472E5E7D" modified="2014-04-16" version="1">MATLIRPPPADHSQSAIENVLELTQLADIDPNIFTNTRPLWHPPGARGIFGGAAIAQTLSAAQKTVDPDFTVHSMHCYFILAGNSEIPVIYHVERVRSGKSFATRTVQARQRGKVIFTTTMSFVRQNSGGAQKVEHIYPMPDVPAPKEGSDDLRTPNDGQSPFQTQLLLIENACPGSYLVDDSDKPHTKRCRQWIKARGKISPAGGHEAHLSAIAYMSDSYFIGTVARAHKLLRYSNQRKSRARSSIDEDVLKKLLEMDDAELQRQSFVNESDKQRIREIRKAEDLAKSGDAKPEIGMMVSLDHTIYFHNPRSFRADEWIFTEMETPWAGDGRGLVSQRMYTKDGTLIASCVQEVSGLLLSVKVDWADMNRALYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9H8</accession>
    <name>W6Z9H8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_4472</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687007.1">
        <property type="nucleotide sequence ID" value="XM_007688817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9H8"/>
    <dbReference type="GeneID" id="19124245"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4472"/>
    <dbReference type="eggNOG" id="KOG3855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_9_3_1"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF7">
        <property type="entry name" value="P-HYDROXYBENZOATE-M-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="5"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="6">
        <location>
            <begin position="409"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="70261" checksum="61746FB0168AF75C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9R0</accession>
    <name>W6Z9R0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">N-terminal nucleophile aminohydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_92635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686997.1">
        <property type="nucleotide sequence ID" value="XM_007688807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9R0"/>
    <dbReference type="STRING" id="930090.W6Z9R0"/>
    <dbReference type="GeneID" id="19128109"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92635"/>
    <dbReference type="eggNOG" id="KOG1592">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021603_1_0_1"/>
    <dbReference type="OrthoDB" id="2262349at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04701">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF43">
        <property type="entry name" value="ASPARAGINASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="302"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="245"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="332"/>
            <end position="335"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="3">
        <location>
            <begin position="216"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="47344" checksum="2EAB27A6BB5C2EF6" modified="2014-04-16" version="1">MDTKQRQTHSAGSVPNTGSIPPRIIIHGGAGNITRGSLSRETYEQYRSALLRILDAAAKKLVDPGATALDVATYAVTLLEEDPLFNSARGAVFTRGGKNELEASVMVSDGYRKRGVGCTLLKRVRNPIQLARELLVRGEEVDGGGGAGDHCFYSGETAEGLARKWGLEIVDPSWFFTQRRWDEHLRGLEEEGKMIGGGGAAQGTSEWEKNHYVPLGTCGAVVVDGYGTICTATSTGGLTNKVDGRVGDTPTIGAGFWAEEWYEDAPAAKMLYQPVPQAMAPIDKLSRGDLYGALDGCLPTLGSSSSRQAAPTPSPENKEPTPIRHAMGLSGTGNGDSFLRTSAARTTAAKSRFSSQPLSDATTWMVGRGGELQKSAGNRWDGVHEGAGGIIGIELVGNKVQVVQDYNCGGMFRAWTEENGSRKCSIFREDKWESGPQSWRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9Y9</accession>
    <name>W6Z9Y9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRISE-like Rossmann-fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964158">
        <property type="protein sequence ID" value="EUC40526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692960.1">
        <property type="nucleotide sequence ID" value="XM_007694770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9Y9"/>
    <dbReference type="GeneID" id="19119272"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108582"/>
    <dbReference type="eggNOG" id="ENOG502SJ55">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030125_1_1_1"/>
    <dbReference type="OrthoDB" id="1731983at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08948">
        <property type="entry name" value="5beta-POR_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055222">
        <property type="entry name" value="PRISE-like_Rossmann-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487:SF29">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22917">
        <property type="entry name" value="PRISE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRISE-like Rossmann-fold" evidence="1">
        <location>
            <begin position="144"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="426" mass="47728" checksum="40475479D60D45E1" modified="2014-04-16" version="1">MTQQVYSDEIYHGLPDLSASPNNLTAIITGTNGLSGSHMLRRLCQNPERWSNIYCLSLHPPYGKHPDHVQHTAVDLLQSPETLAAILIAANVQAEYVFYFSHVQPPPKPGMGLWSDAGEVTRLNSLIFQNLLGGLAGARIIPRRILLQAGAKYYGGHLGPMKVPQVETDPRVDLEPNFYYSQEDSLVEYCAGGSGERRTRWNIILPGPLVGAAPRSAMNVAFPLAVYASICRKLNQSLEYPSDVVSWQMPLAMSSAGLNAHMEEWAVLTPGAADQRINQCDNSTFTWEGFWPCLAEWYGISWKGPEEDVEWIEFEMPYRPRGYGPKGVLRWKFTFGSWSQQPHVQQAWRALTDEHGLIKRELSDLSKEFAFLDGCVSLYTALLPSMNKARKLGWHGFVDTSDAFFQVFRELSALKMVPPMPLLGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9Z8</accession>
    <name>W6Z9Z8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_91760</name>
    </gene>
    <organism evidence="2 3">
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            <taxon>Pleosporales</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
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                <person name="Han J."/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="791"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="824"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="998" mass="112247" checksum="BB000E6C9EE3B9A6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAD0</accession>
    <name>W6ZAD0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyltransferase family 62 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_91502</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686605.1">
        <property type="nucleotide sequence ID" value="XM_007688415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAD0"/>
    <dbReference type="GeneID" id="19127894"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91502"/>
    <dbReference type="eggNOG" id="ENOG502QVDT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017872_4_2_1"/>
    <dbReference type="OrthoDB" id="204164at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000017">
        <property type="entry name" value="Mannan polymerase II complex ANP1 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF4">
        <property type="entry name" value="N-GLYCOSYL-TRANSFERASE (AFU_ORTHOLOGUE AFUA_4G06870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="406" mass="46072" checksum="089A2F0C63FA0098" modified="2014-04-16" version="1">MLAGKGYSWKAAQARLPPSRQVLHTARNPRFLLSLGLLTAVILLWRSMGSATGELQRFYCFGPSKPPMHMSPNENEDWHAHLTTPVVFNHHKPIEVNATDIQHVNLNSIKSTPNAVKNKERVLILTPLRDASFYLPKHFDLLAQLTYPHDLIDLAFLVGDTTDDTVAVLAKELERIQNNPEIAFRSTMIVEKDFGVTLSQSVEDRHGFEAQGPRRKALGRARNYLLATALKPDHSWVYWRDVDIVDSPSKIIEDFVAHDRDVLVPNIWFHRYKEENGKKVDIEGRFDYNSWQESPEGLKLAASLDKNVVLAEGYKQYPTHRKYMAKMGDWRADKDEEIPLDGVGGVNIIVKADVHRSGINFPCYAFENQAETEGFAKMARRAGYGVYGLPNYVVWHIDTDEKPGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAJ2</accession>
    <name>W6ZAJ2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Autophagy-related protein 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Autophagy-related E2-like conjugation enzyme ATG3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_108079</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964144">
        <property type="protein sequence ID" value="EUC40721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692773.1">
        <property type="nucleotide sequence ID" value="XM_007694583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAJ2"/>
    <dbReference type="STRING" id="930090.W6ZAJ2"/>
    <dbReference type="GeneID" id="19119180"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108079"/>
    <dbReference type="eggNOG" id="KOG2981">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027518_2_0_1"/>
    <dbReference type="OrthoDB" id="1584384at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="351" mass="39170" checksum="3671A74BDA8EE022" modified="2014-04-16" version="1">MAYNFVRSYIDTFRERTAAISHTSTFRETGQITPEEFVLAGDFLVFKFPSWQWADASSPSKRVSYLPEGKQFLVTRGVPCHRRLDDNFAGEAGQDETIVRDGFTAGEGATDDDGWLRTGGMAASQEAKVRDVRTVDESGNLGAAEDDDEIPDMEDIEDDDEAIIRDPQAESNTQAPLRTYTLYITYSAHYRTPRLYLSGYGSTSVPLKPQEMMEDIVGDYKDKTVTIEDFPFFENPLKTASVHPCKHASVMKVLLDRADAALKLRLAKLKAGKDVSKLDSGMEALVDDTRLLKLTEQAKGKDGEEAKDDWEVLSEGDDEEVAIRVDQYLVVFLKFMASVTPGIEHDFTMGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAK7</accession>
    <name>W6ZAK7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Lanosterol 14-alpha-demethylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_37644</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688940.1">
        <property type="nucleotide sequence ID" value="XM_007690750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAK7"/>
    <dbReference type="STRING" id="930090.W6ZAK7"/>
    <dbReference type="GeneID" id="19123294"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37644"/>
    <dbReference type="eggNOG" id="KOG0615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006880_0_0_1"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008398">
        <property type="term" value="F:sterol 14-demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11042">
        <property type="entry name" value="CYP51-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000033">
        <property type="entry name" value="14-alpha sterol demethylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001380">
        <property type="entry name" value="Checkpoint kinase 2-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="696"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="731"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="17">
        <location>
            <begin position="181"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="272"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="602"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="1145"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC44554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="21">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1204" mass="135465" checksum="D17EDEAB43C3786F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAZ5</accession>
    <name>W6ZAZ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_90843</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686355.1">
        <property type="nucleotide sequence ID" value="XM_007688165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAZ5"/>
    <dbReference type="STRING" id="930090.W6ZAZ5"/>
    <dbReference type="GeneID" id="19127766"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90843"/>
    <dbReference type="eggNOG" id="KOG2275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_3_0_1"/>
    <dbReference type="OrthoDB" id="3064516at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05652">
        <property type="entry name" value="M20_ArgE_DapE-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050072">
        <property type="entry name" value="Peptidase_M20A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF8">
        <property type="entry name" value="PEPTIDASE M20 DIMERISATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886825" description="Peptidase M20 dimerisation domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="7">
        <location>
            <begin position="216"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="412" mass="44023" checksum="0CD6D8728A10A717" modified="2014-04-16" version="1">MALIKSILALLAFQLASAAPQASVTSSAISSPSPTGLDPAVALSTEEVEKLYSLHEELVNIPSISGNEIECADFVSKYLADLGYYVDKVPVNETGTYNVFAYPQALKDEGVWPEVLVTSHIDTVPPFYPFERRERNGTTYHFGRGTVDAKGPVATMIIASHKFLQSRNETTSLGLLFVVSEENSGAGMRAFAKYASNTTFRAGIFGEPTEGKLASGHKGSFGITLKAIGKASHSAYPWLGVSAINYVVDAISALRALEPALPKSDLLGVSTLNTGLIAGGVASNVVPPNANASVLVRVARSEANAVDTIKDMISGLFAPLVNSAKEVNATFEYTYSTLSTRAQILDTDIEGLEVAPVFYGTDIPNLPQVEKRYLYGTGTIEVAHTPDEMLSQEELVQAAEAYGAILRTIFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB58</accession>
    <name>W6ZB58_COCMI</name>
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        <recommendedName>
            <fullName evidence="8">TM7S3/TM198-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_23215</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684394.1">
        <property type="nucleotide sequence ID" value="XM_007686204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB58"/>
    <dbReference type="GeneID" id="19120392"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23215"/>
    <dbReference type="eggNOG" id="ENOG502RXUE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003667_0_0_1"/>
    <dbReference type="OrthoDB" id="102260at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39469">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39469:SF1">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887331" description="TM7S3/TM198-like domain-containing protein" evidence="7">
        <location>
            <begin position="24"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="8">
        <location>
            <begin position="132"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="385"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="461"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="594"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="743"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="822"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="868"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="507"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="622"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="642"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="674"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="778"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="879"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="947"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC49027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1046" mass="113064" checksum="01FEC7030B50AF5E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB78</accession>
    <name>W6ZB78_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684443.1">
        <property type="nucleotide sequence ID" value="XM_007686253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB78"/>
    <dbReference type="GeneID" id="19126704"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85664"/>
    <dbReference type="eggNOG" id="ENOG502SYSW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135732_1_0_1"/>
    <dbReference type="OrthoDB" id="4788795at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886829" evidence="1">
        <location>
            <begin position="21"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="132" mass="14599" checksum="52BAEDD2D926FFA7" modified="2014-04-16" version="1">MHFSTLSLSILPFLATTASAASCTIDGSAAAYHWEVRASGVYGIPGWCGGLWDNLNRWGGLCNPSYPYCNGQDGEMVWRFTTSVGCMRGHVESVWWEATKNEFGAITCVDAPEKREVLDAPEDKKKREEFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBG0</accession>
    <name>W6ZBG0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_107185</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="KI964122">
        <property type="protein sequence ID" value="EUC41066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692426.1">
        <property type="nucleotide sequence ID" value="XM_007694236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBG0"/>
    <dbReference type="STRING" id="930090.W6ZBG0"/>
    <dbReference type="GeneID" id="19119000"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107185"/>
    <dbReference type="eggNOG" id="KOG2246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022549_3_1_1"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.50:FF:000039">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF43">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="12">
        <location>
            <begin position="167"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC41066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="446" mass="51441" checksum="D29BAC2451636686" modified="2014-04-16" version="1">MMVRLTPLRLLSAALLLCALFLTTLLPRLWRGDRGYDLLVDRPPPAGPGPVPKVVVPFGQECAPFTAGVMDDVTIVLKIGAGEVASKLPQYLNRLGRCKQDLLIFSDRKDSYNGFDIADALAHLRPEYRFNNPDFDIYDYIQSVNLTTDKSPDGWRLDKYKFLPMMEWTSYLRPQSQWYVFLELDTYVNYDNLYRFLSNFNPRTAYYFGSPVWPKKKAIFAHGGSGFVLSRAALDKIMAQGRMFGENKHFPGTHFFGVDVQKQCCGDEILAQVLKKSGVSLRGYWPMFNGEKPITMRFDNEQWCEAIMTMHHLNEEDFTSLSQWEKARSHPDRPLMFEELFTMIEPHLRRESEDWSNLSEDVTYKPSKKASKSFDHCRKACINDSSCMQFQHTGTECRLGYSIRLGRHQPREGDRQSKSGWMLDRIKAFKQARSPCQGARFVHSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCK4</accession>
    <name>W6ZCK4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_84372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684043.1">
        <property type="nucleotide sequence ID" value="XM_007685853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCK4"/>
    <dbReference type="STRING" id="930090.W6ZCK4"/>
    <dbReference type="GeneID" id="19126452"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84372"/>
    <dbReference type="eggNOG" id="KOG1729">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082207_0_0_1"/>
    <dbReference type="OrthoDB" id="10018316at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15760">
        <property type="entry name" value="FYVE_scVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164:SF30">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="163"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC49547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="274" mass="30350" checksum="52DA4D6F6F6573F7" modified="2014-04-16" version="1">MATTFSTTTTTTFPQHAPYQHHAYRKSTHSQYSPTNSAINTPANISPTSPRNTHLPLSRHQGIYQPRTAIGIPAALRKTERPASKSPPKQDSGAESNNTNPWSTNAGFEWAANDGSITPISHIGNEDMQSLYSPEPLSPVAGPITRNHWQADASTLVCSASSCQEPFGFFQRRHHCRKCGGIFCAQHSRNQVRLDELARFHPQGHWHRACDRCHSSFREWEHLRSSRTNSESSDSSGPAPAKSIQTPAIAKRPDNTRVGSLAQSLQGTWNWSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCR5</accession>
    <name>W6ZCR5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_34841</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CKS family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685839.1">
        <property type="nucleotide sequence ID" value="XM_007687649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCR5"/>
    <dbReference type="STRING" id="930090.W6ZCR5"/>
    <dbReference type="GeneID" id="19122652"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34841"/>
    <dbReference type="eggNOG" id="KOG3484">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140546_0_0_1"/>
    <dbReference type="OrthoDB" id="440676at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.170.10:FF:000002">
        <property type="entry name" value="Cyclin-dependent kinases regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00296">
        <property type="entry name" value="CYCLINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00944">
        <property type="entry name" value="CKS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00945">
        <property type="entry name" value="CKS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00068939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="117" mass="14077" checksum="360C215F54DFD1F0" modified="2014-04-16" version="1">MSGDLDIDFTRRNKKPRPLSEHEKEKLDEFVDAIHYSARYSDDVYEYRHVQLPKQMLKAIPKDYFDGARGTLKLLWEEEWRALGITQSLGWEHYEVHEPEPHILLFKRPINYQPPMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCY6</accession>
    <name>W6ZCY6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATPase inhibitor, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_89200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Inhibits the enzyme activity of ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ATPase inhibitor family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685723.1">
        <property type="nucleotide sequence ID" value="XM_007687533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCY6"/>
    <dbReference type="STRING" id="930090.W6ZCY6"/>
    <dbReference type="GeneID" id="19127425"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89200"/>
    <dbReference type="eggNOG" id="ENOG502SCJG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145563_0_0_1"/>
    <dbReference type="OrthoDB" id="5532350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042030">
        <property type="term" value="F:ATPase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007648">
        <property type="entry name" value="ATPase_inhibitor_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48417">
        <property type="entry name" value="ATP SYNTHASE F1 SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48417:SF1">
        <property type="entry name" value="ATP SYNTHASE F1 SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04568">
        <property type="entry name" value="IATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64602">
        <property type="entry name" value="F1 ATPase inhibitor, IF1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="104" mass="11377" checksum="B6C457DD0DBD8AF3" modified="2014-04-16" version="1">MLRTSIIKSARSIAAPRYFSASALRMAEGATGSGTSRPTGTAGGDAFTKREAAAEELYIRQEEKAKLLAIKAKLRQQREHMDELDKHIDQVIQESEASGQGEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE27</accession>
    <name>W6ZE27_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_26169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687765.1">
        <property type="nucleotide sequence ID" value="XM_007689575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE27"/>
    <dbReference type="GeneID" id="19120889"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26169"/>
    <dbReference type="HOGENOM" id="CLU_836749_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="332" mass="36118" checksum="5ED8E44D95CD20B1" modified="2014-04-16" version="1">MLHDSCPCEGSVSGCQTGSAQHKRSAGLRCRIVPGSVLAHTSALQTQSDRHDACARYRLLLRRRRRRRRRPSVVSSKPCLLALPLPSPPQPPLPPLPSLPSACSPILSVWPILSVPQRTPNLAADPIVARAQQVASSAKRRLHPPPPLVFCLSPPLPDAHVCATTKLSPSANRTQSHTTGPARPRCTYKTQHRPSWPPSRPCIPATLVVDPDAFPAWRATSLLRIAHLLWLERSDQHHHQHHHCHSPPPTSTLPLHPEFASPRPTDGTPAYPTTTLISPHTFDLLFFPTTTTTTTTAATAATATAAALLFFVFTAATTLYTPSSHTSHCALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE99</accession>
    <name>W6ZE99_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_58970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687697.1">
        <property type="nucleotide sequence ID" value="XM_007689507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE99"/>
    <dbReference type="GeneID" id="19124771"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_58970"/>
    <dbReference type="HOGENOM" id="CLU_3129634_0_0_1"/>
    <dbReference type="OrthoDB" id="10364488at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="50" mass="5567" checksum="0C7095C49DDC5297" modified="2014-04-16" version="1" fragment="single">SIPLIHTHTQTMVIAHFISCVFHDETLVQGARQPRTACYSSCLDICALTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZED9</accession>
    <name>W6ZED9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sterol regulatory element-binding protein cleavage-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_82634</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat SCAP family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683320.1">
        <property type="nucleotide sequence ID" value="XM_007685130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZED9"/>
    <dbReference type="STRING" id="930090.W6ZED9"/>
    <dbReference type="GeneID" id="19126094"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82634"/>
    <dbReference type="eggNOG" id="KOG1933">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004183_0_0_1"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032936">
        <property type="term" value="C:SREBP-SCAP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045540">
        <property type="term" value="P:regulation of cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032933">
        <property type="term" value="P:SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030225">
        <property type="entry name" value="SCAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46378">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46378:SF1">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="15" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="409"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="605"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="17">
        <location>
            <begin position="276"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC50177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1150" mass="127470" checksum="8658E026747A715A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEH0</accession>
    <name>W6ZEH0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_36416</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687574.1">
        <property type="nucleotide sequence ID" value="XM_007689384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEH0"/>
    <dbReference type="STRING" id="930090.W6ZEH0"/>
    <dbReference type="GeneID" id="19123022"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36416"/>
    <dbReference type="eggNOG" id="KOG3030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021458_0_0_1"/>
    <dbReference type="OrthoDB" id="10030083at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.144.10:FF:000035">
        <property type="entry name" value="Putative Lipid phosphate phosphatase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF84">
        <property type="entry name" value="PHOSPHATIDIC ACID PHOSPHATASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="138"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="412" mass="44689" checksum="F7359B25A3395FD2" modified="2014-04-16" version="1">MGLFNKRNTTPVAADTTTATGSHREKRPRRHSKSHSSSYNSRPSFGQWLKATWLDILTMAAMGAIGLGVYMADPAPSRSFPIVFQDGEIVYPEFAYPLRNEIIPIWAAALMAFFIPFAVFLIVQIRARSFWDVNNATVGLLYSLITAAVFQVFIKWLIGGLRPHFLAVCKPVIPENLRSSVGAADNGIESGSGNGNVANGYRQIMFDKSICTGDMNEINDSLESMPSGHTTAAFAGFVFLYLYLNAKLKVFSNHHPAMWKLVALYAPILGACLIGGALTIDEYHNWYDVLAGAVIGTIMAFSAYRMTYASIWDFRFNHIPLMRHAPFVYGAGPSSFDGFHDAIFTRKAGWGTHDAGSWGGAPFDAADGPRGTMMPQAEGPAGSHVNRKPVGHGAGVGHGAGVGHGVRGEHMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFB6</accession>
    <name>W6ZFB6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zygote-specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687291.1">
        <property type="nucleotide sequence ID" value="XM_007689101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFB6"/>
    <dbReference type="STRING" id="930090.W6ZFB6"/>
    <dbReference type="GeneID" id="19122954"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36139"/>
    <dbReference type="eggNOG" id="ENOG502S6ZF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166294_1_0_1"/>
    <dbReference type="OrthoDB" id="10063670at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475">
        <property type="entry name" value="ZYGOTE-SPECIFIC CLASS V COPY B GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475:SF1">
        <property type="entry name" value="ZYGOTE-SPECIFIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889789" description="Zygote-specific protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="8243" checksum="52BB0A69F75CDC8D" modified="2014-04-16" version="1">MKPLSLTKIAIAVLSLTAGQASAGPVGYAVCQAGCAGVVMACYSAAGFTWGATFGATAPASILLCNAAFGKCQAACAFVLLGPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFG0</accession>
    <name>W6ZFG0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_104111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964069">
        <property type="protein sequence ID" value="EUC42206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691274.1">
        <property type="nucleotide sequence ID" value="XM_007693084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFG0"/>
    <dbReference type="GeneID" id="19118443"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104111"/>
    <dbReference type="HOGENOM" id="CLU_2527123_0_0_1"/>
    <dbReference type="OrthoDB" id="3672618at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="84" mass="9118" checksum="E69DF33926C34CA4" modified="2014-04-16" version="1">MLGHYQRVATISTHCIAFAAETPYCAWDANVAEMLDHASLVAPSRVCIQCASLALTTASSTRYHVDTWCHGGPLDWCISASAQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFM7</accession>
    <name>W6ZFM7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cystathionine beta-lyase</fullName>
            <ecNumber evidence="3">4.4.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cysteine-S-conjugate beta-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_2541</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L,L-cystathionine + H2O = L-homocysteine + pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13965"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:18121"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29256"/>
            <dbReference type="ChEBI" id="CHEBI:58717"/>
            <dbReference type="EC" id="4.4.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homocysteine from L-cystathionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.13" evidence="3"/>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684808.1">
        <property type="nucleotide sequence ID" value="XM_007686618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFM7"/>
    <dbReference type="STRING" id="930090.W6ZFM7"/>
    <dbReference type="GeneID" id="19120757"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2541"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_1_1"/>
    <dbReference type="OrthoDB" id="2545919at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047804">
        <property type="term" value="F:cysteine-S-conjugate beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000013">
        <property type="entry name" value="Cystathionine beta-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000009">
        <property type="entry name" value="Cystathionine gamma-synthase homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006238">
        <property type="entry name" value="Cys_b_lyase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01329">
        <property type="entry name" value="cysta_beta_ly_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF50">
        <property type="entry name" value="CYSTATHIONINE BETA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 13 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="13">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC48678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="452" mass="48643" checksum="C85A32F3B80A5BA3" modified="2014-04-16" version="1">MAGESSKKTNASGKAALPLDIDGHNLPPSPAPSSPRNGRKYALMTELVYTESSDQYNASSVPIYQSATFKQESASGGGGEYDYTRSGNPTRTHLERHLAKIMNANRALVVSSGMGALDVITRLLRPGDEVITGDDLYGGTNRLLKYLSTHGGIIVHHVDTTNPEKVREVVNNKTAMVLLETPTNPLIKICDIPTIANIAHAANPTAIVAVDNTMMSPMLLNPLDLGSDIVYESGTKYLSGHHDLMAGVIAVNDSALGDRLYFTINASGCGLSPFDSWLLLRGIKTLGVRMEKQQENAMRIATFLESHGFKVRYPGLKSHPQYDLHWSMARGAGAVLSFETGDVTVSERIVESARLWGISVSFGCVNSLISMPCRMSHASIDEKTRKERNMPEDIIRLCVGIEDPEDLIDDLSRALVQAGAVNITTEGFQALAAEAPAPTQPSEAAAPAPTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFY2</accession>
    <name>W6ZFY2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_33615</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684516.1">
        <property type="nucleotide sequence ID" value="XM_007686326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFY2"/>
    <dbReference type="STRING" id="930090.W6ZFY2"/>
    <dbReference type="GeneID" id="19122363"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33615"/>
    <dbReference type="eggNOG" id="KOG0271">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_4_1"/>
    <dbReference type="OrthoDB" id="6262491at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001196">
        <property type="entry name" value="WD repeat protein (AFU_orthologue AFUA_1G12380)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="77"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="119"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="257"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC48940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="378" mass="41564" checksum="BE4BE6CC5E6B8438" modified="2014-04-16" version="1">MSLSNDPGHYFQTTSALEETARKAAKSKNTKGNPTKLPSKILAVIADPQDEHHVYVAEAAGSVKHINIETSKVVATFSGPTAPLTSIAVSPKSGTLFAGCWDKSIWSWSLSSRKVSTRFQGHSDFVKAIISFTLNGKEVLVSASQDASIIVWDVAAGKKLHTLKGHTRGILALALDPVDYEPGKDAITVFSAGSDREIRRWQIASSSACEIQPSPIISHETSIDALHFDTDGDLWTASADKTAKCLSRGRDWEEDSKFEHPDFVRDVVIDEAGGWIVTACRDEEVRVWERASGRLHHTFSGHFEEVTGLLLMGQRLISVSIDATVRQWSLKPQELAKAIEEAEKERLGEETAKEPERKESLMTLEEEAELAELLEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG02</accession>
    <name>W6ZG02_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_28921</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="KI964061">
        <property type="protein sequence ID" value="EUC42431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691029.1">
        <property type="nucleotide sequence ID" value="XM_007692839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG02"/>
    <dbReference type="STRING" id="930090.W6ZG02"/>
    <dbReference type="GeneID" id="19121407"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28921"/>
    <dbReference type="eggNOG" id="ENOG502RS1Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075887_0_0_1"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF13">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="11"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="313" mass="35279" checksum="079A9DB8D6CB88EA" modified="2014-04-16" version="1">MPYTLPPKAFLTLKKLTHHGDAGAHNQGIYLTQHLPTAKVYIEKRLLPSRAAKREILAMRLCNPHPHLVSIFTSTQSTSIISIYMQHCELGSLDTLILHFNAHATRLHDEGFVFRVFWHLALALCYLSTGADYATTRDRAFRGKSAVRKKGWHGMVHRDIKPGNVFLTRNRECKGADAHTLYPCVVLGDFGCVGAGSERYSRHARVLGRGDPRFEAPEREGNAYSDVFSVGLVLHCLARMVQVPDENLLPDRPLGGQYTGCRHLAKMVRDCLKWTPEERPSPLELPRLVFEGYRVWRQARGCDGVALPKWAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG28</accession>
    <name>W6ZG28_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_21780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682664.1">
        <property type="nucleotide sequence ID" value="XM_007684474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG28"/>
    <dbReference type="GeneID" id="19120119"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21780"/>
    <dbReference type="HOGENOM" id="CLU_745938_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="371" mass="41738" checksum="B8A6B6CE03C459C0" modified="2014-04-16" version="1">MRSEKKGTYIHQPPSSFRPLHPISLSSTIRLNQPRNHSFPHTHTRISILHLLPNPHLKHAKEKSGLRVGLQVEPNHPIRLTRVGTQADITVTPTPKRTLAKFKEAVIINCFFTCYPLLFRLGSLGVYRNASTAYDGPFEDKWGAKRVACTFGNRNCITTRGDKGLGGSHQGLYEEVLNRKGGAGSCGWIVVDSSETCFSSTFKEELVALVYLKVQIGDAVSSIYWSFRSGGIYKRTFWVSTCIRYHGQTRRSRLGLGCMTAWGREKKKGVVDGKGDIKRTLASCVIYPARSVISHVSTWSMHDTRPRCSPAIFRDYNCAESSGVESNNHEASTKKDQLKLTRQKNKNNDNQMQSIDVGSAIRFHYWLALHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGB9</accession>
    <name>W6ZGB9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_39395</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964057">
        <property type="protein sequence ID" value="EUC42551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690924.1">
        <property type="nucleotide sequence ID" value="XM_007692734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGB9"/>
    <dbReference type="STRING" id="930090.W6ZGB9"/>
    <dbReference type="GeneID" id="19123676"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39395"/>
    <dbReference type="eggNOG" id="KOG3009">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012201_3_0_1"/>
    <dbReference type="OrthoDB" id="198885at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01941">
        <property type="entry name" value="YeiC_kinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="entry name" value="Indigoidine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01876">
        <property type="entry name" value="PsiMP_glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
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            <begin position="734"/>
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        </location>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42551.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="802" mass="84894" checksum="B6B4B74F9EB4987D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGF4</accession>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_21627</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_21627"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
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    </feature>
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        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
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        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="109" mass="12284" checksum="997B3894FBCF4E6F" modified="2014-04-16" version="1">MRQPKKSNGAQRTNQAISDNAQIRPSAITNYAMEREVKCFNSTLALRIQMFARLHMVTQSRRTIQSAASLPASPLSRLVTKNPPMRRTDYGAEDRSPSSSTQRADEQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGL6</accession>
    <name>W6ZGL6_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_21688</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGL6"/>
    <dbReference type="GeneID" id="19120106"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21688"/>
    <dbReference type="eggNOG" id="ENOG502R29K">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_436129_0_0_1"/>
    <dbReference type="OrthoDB" id="3767399at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
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        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="555"/>
            <end position="609"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="64"/>
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        </location>
    </feature>
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        <location>
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            <end position="199"/>
        </location>
    </feature>
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        <location>
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            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="277"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="516"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="627" mass="69380" checksum="A977C3C16D39342D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGP5</accession>
    <name>W6ZGP5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_80071</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Vacuole membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ATG22 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGP5"/>
    <dbReference type="STRING" id="930090.W6ZGP5"/>
    <dbReference type="GeneID" id="19125596"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80071"/>
    <dbReference type="eggNOG" id="ENOG502QTJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017518_2_0_1"/>
    <dbReference type="OrthoDB" id="42657at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF5">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
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            <end position="182"/>
        </location>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
            <dbReference type="RuleBase" id="RU363073"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC51027.1"/>
        </source>
    </evidence>
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        <source>
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</entry>
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    <accession>W6ZGS6</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="EMBL" id="EUC42696.1"/>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
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                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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    </evidence>
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        <source>
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</entry>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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            <dbReference type="EMBL" id="EUC46879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="74" mass="8737" checksum="A42064247531A130" modified="2014-04-16" version="1">MCSYTYSWYYCNHDYYIWANSIEVCSSRLLSGYSYDAWSIDMCSKMKIECGGFSNYYCTDCSEDVALEFELDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI96</accession>
    <name>W6ZI96_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">alpha,alpha-trehalase</fullName>
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    </protein>
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        <name evidence="7" type="ORF">COCMIDRAFT_90915</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 65 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="3"/>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686357.1">
        <property type="nucleotide sequence ID" value="XM_007688167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI96"/>
    <dbReference type="STRING" id="930090.W6ZI96"/>
    <dbReference type="GeneID" id="19127786"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90915"/>
    <dbReference type="eggNOG" id="KOG4125">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006285_4_0_1"/>
    <dbReference type="OrthoDB" id="200349at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GH65_N"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR005196">
        <property type="entry name" value="Glyco_hydro_65_N"/>
    </dbReference>
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        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11051:SF8">
        <property type="entry name" value="PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03632">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887082" description="alpha,alpha-trehalase" evidence="4">
        <location>
            <begin position="23"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 N-terminal" evidence="6">
        <location>
            <begin position="49"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 central catalytic" evidence="5">
        <location>
            <begin position="400"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1012" mass="112099" checksum="EB81B6F9FF10C258" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIT1</accession>
    <name>W6ZIT1_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_22462"/>
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    </dbReference>
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            <end position="80"/>
        </location>
    </feature>
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        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
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        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="156" mass="17646" checksum="5D9F0B31C5C07236" modified="2014-04-16" version="1">MQVTQYYFYYGNPPGLKSAGTWGRGPVSRVCRRGNTVRYLYTRLEDVLSSALQPTALANRCDTQEERRQDEKDEQVLPNLPAGFQGPNGAIAEAYYLHEMTNKVILLRFLISPIPQLCSKQKWVTRKECGSCSLLCPSRSDSSSAATHRRSTRKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
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    <name>W6ZJ49_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_38429</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964023">
        <property type="protein sequence ID" value="EUC43626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689832.1">
        <property type="nucleotide sequence ID" value="XM_007691642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ49"/>
    <dbReference type="STRING" id="930090.W6ZJ49"/>
    <dbReference type="GeneID" id="19123461"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38429"/>
    <dbReference type="eggNOG" id="KOG0578">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076146_0_0_1"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="296" mass="33734" checksum="DF37D217D35BD2C7" modified="2014-04-16" version="1">MPPLFKVDQVLRGHKSIYITVKEVHRALDEAAVYVASVRGHWCLQNEADILGRYQSKTPFLRPIIDEVISPADPPSIILRHLDSELLTESTNKRPTRPETKQVARCILEALLVLHRDGMRFLETQLGNCGGAVSKDSKFAEGNLIGGAFTHLPTDVWSFGNAILSLVHGGDFHYFDPGRQGVKLEDREYDLIVMQRMYHSSGPFQKSVAEILNLVALELVIFFSGQRIPRKPLQRWSTKEIPSADNKFIRRILKLDPRERPMVEEIFEDEWFMEESDDTREPIPKETSKPEDEAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJV7</accession>
    <name>W6ZJV7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_89478</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687597.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19127487"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89478"/>
    <dbReference type="eggNOG" id="ENOG502QW6D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011003_0_1_1"/>
    <dbReference type="OrthoDB" id="4060227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC47724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="677" mass="75399" checksum="4BB6B6427B249004" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLI0</accession>
    <name>W6ZLI0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_80884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682772.1">
        <property type="nucleotide sequence ID" value="XM_007684582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLI0"/>
    <dbReference type="GeneID" id="19125759"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80884"/>
    <dbReference type="eggNOG" id="ENOG502QSHE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009942_1_1_1"/>
    <dbReference type="OrthoDB" id="3501663at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase 3" evidence="2">
        <location>
            <begin position="82"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="575" mass="63733" checksum="695419DCBB770F56" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMK1</accession>
    <name>W6ZMK1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_31461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682143.1">
        <property type="nucleotide sequence ID" value="XM_007683953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMK1"/>
    <dbReference type="GeneID" id="19121876"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31461"/>
    <dbReference type="eggNOG" id="ENOG502T1VM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076685_0_0_1"/>
    <dbReference type="OrthoDB" id="3914029at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="257" mass="27626" checksum="CDF5EDE8F18AD094" modified="2014-04-16" version="1">MSEKHNNAAPPPPYSPHASSVSPSILDQLNITRTQHIESVIDTHILPLIHQRITYAMVTTTLALLPSDTSLAPTKANAYSSAFLQDSPSSPDSSTSIQVLGFASDTSPPHLIHLSGPINSTEFWNLPPVLHELETILTSRLNPHSTPMPTAPSSYRDTTLSPPNAAGGAASAQILPPQRFSRRSLLARVMPSLGPEQASPGNNPEVGVRHIDNAASGTNMVTVKARWEEICLRTVSDFGLYDTISKQCVIIKVDAQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMW0</accession>
    <name>W6ZMW0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_79270</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682286.1">
        <property type="nucleotide sequence ID" value="XM_007684096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMW0"/>
    <dbReference type="STRING" id="930090.W6ZMW0"/>
    <dbReference type="GeneID" id="19125438"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79270"/>
    <dbReference type="eggNOG" id="KOG3467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109117_4_0_1"/>
    <dbReference type="OrthoDB" id="3687090at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000012">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="11">
        <location>
            <begin position="14"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC51435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="89" mass="10085" checksum="CB08EC929B200910" modified="2014-04-16" version="1" fragment="single">GAKRHRKILRDNIQGITKPAIRRLARRGGVKRISAMIYEETRGVLKTFLEGVIRDAVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNJ8</accession>
    <name>W6ZNJ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_85710</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684469.1">
        <property type="nucleotide sequence ID" value="XM_007686279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNJ8"/>
    <dbReference type="STRING" id="930090.W6ZNJ8"/>
    <dbReference type="GeneID" id="19126718"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85710"/>
    <dbReference type="eggNOG" id="KOG1494">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047181_1_0_1"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="148"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="8"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC49104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="327" mass="33855" checksum="20D660165C397B94" modified="2014-04-16" version="1">MVKAVVAGASGGIGQPLSLLLKNNQHVTELALYDVVNTPGVAADLSHISTPAIVKGYLPKDDGLKGALTGADIVVIPAGIPRKPGMTRDDLFKINAGIVKGLIEGIAQFCPKAFVLIISNPVNSTVPIAAEVLKKAGVFDPKKLFGVTTLDVVRAETFVAEIIGEKNPGNLNIPVIGGHSGETIVPLFSQAKPSVNIPADKLEALVKRVQFGGDEVVQAKDGAGSATLSMAYAGYRFAEKVIKAANGEKGIVEPSYVYLPGVEGGDAIAKATGTEFFSVPIELGPSGAEKAIDVVSSANDHEKTLLKACYEGLGGNITKGVEFVKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPM7</accession>
    <name>W6ZPM7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_95291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687956.1">
        <property type="nucleotide sequence ID" value="XM_007689766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPM7"/>
    <dbReference type="STRING" id="930090.W6ZPM7"/>
    <dbReference type="GeneID" id="19128626"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95291"/>
    <dbReference type="eggNOG" id="KOG2308">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002680_0_1_1"/>
    <dbReference type="OrthoDB" id="69269at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004177">
        <property type="entry name" value="DDHD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF6">
        <property type="entry name" value="PHOSPHOLIPASE C1020.13C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02862">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="716"/>
            <end position="912"/>
        </location>
    </feature>
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        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="517"/>
        </location>
    </feature>
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        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="938" mass="104093" checksum="B087AFEB07D1F0DD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPU9</accession>
    <name>W6ZPU9_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">Copper homeostasis protein cutC homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_84424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutC family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685835.1"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Copper homeostasis (CutC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="COPPER HOMEOSTASIS PROTEIN CUTC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CutC-like"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="221" mass="23616" checksum="F65B28B61707BFBC" modified="2014-04-16" version="1">MLEIAAFTAPSAIIASQSGATRIELCTSYALGGTTPSHSTLSIVRSATPLPITVMIRPRGGDFVYSTSEYSTMESEIASLKGLADGFVFGILDAEGRVDEERCTRLVRLAEPRACTFHRAIDDARDLREGVEAVVKCGFKRVLTSGGEKSAVEGVERICRLQEVFGGRIEIIAGGGVRSGNVGVVKGTTGVPWVHSAAVTREGEEVDGEEVRRIRELLEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQE5</accession>
    <name>W6ZQE5_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Polynucleotide 5'-hydroxyl-kinase GRC3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Polynucleotide 5'-hydroxyl-kinase grc3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_32936</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Polynucleotide 5'-kinase involved in rRNA processing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Clp1 family. NOL9/GRC3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685575.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZQE5"/>
    <dbReference type="GeneID" id="19122211"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32936"/>
    <dbReference type="eggNOG" id="KOG2750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_411112_0_0_1"/>
    <dbReference type="OrthoDB" id="4054781at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051731">
        <property type="term" value="F:polynucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000448">
        <property type="term" value="P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF3">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Clp1 P-loop" evidence="10">
        <location>
            <begin position="243"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="658" mass="72673" checksum="70F3DAEA985D2E80" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQK6</accession>
    <name>W6ZQK6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_94156</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687547.1">
        <property type="nucleotide sequence ID" value="XM_007689357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQK6"/>
    <dbReference type="STRING" id="930090.W6ZQK6"/>
    <dbReference type="GeneID" id="19128401"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94156"/>
    <dbReference type="eggNOG" id="KOG0062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_6_1"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF135">
        <property type="entry name" value="ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16440)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="45"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="477"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="747" mass="81513" checksum="F4B72BDF6A37AB4B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRE1</accession>
    <name>W6ZRE1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein prenylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_82996</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683455.1">
        <property type="nucleotide sequence ID" value="XM_007685265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRE1"/>
    <dbReference type="STRING" id="930090.W6ZRE1"/>
    <dbReference type="GeneID" id="19126167"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82996"/>
    <dbReference type="eggNOG" id="ENOG502S6DV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044597_0_0_1"/>
    <dbReference type="OrthoDB" id="5358702at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008318">
        <property type="term" value="F:protein prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF3">
        <property type="entry name" value="PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="39625" checksum="DDBEC53DE8EDB362" modified="2014-04-16" version="1">MDSDVSKKSQLQKLAYISLTEYFQEHDNEVVEITILPPSVQPPDGVLIQEGSSLGISKKALTLAYMEARRLFFENRQSNDPSTINQTTQATKIILLFDPEHLTAANYRKRVLAQLESEHKLHAGNIFPKALQRELYFLDSVLTSPLHRQSKSPTLWYHRSRIVDSLILVHLTDTSDDQRMVFWNNELEAVCKSGEQHPKNYHAWQYARRLVQKAHSLGQDDQFAQLVKKWCCRHPSDISGWSFLLYLMPRLAPSLRQELVSNVLDYAIKFSIENESLWVFIRTALAQNMSSADHSVAYRRLQDYVQNLTNKERPQDEAHAASNALKWIDTYGRHIGSQRVVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZS91</accession>
    <name>W6ZS91_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_21998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682983.1">
        <property type="nucleotide sequence ID" value="XM_007684793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZS91"/>
    <dbReference type="GeneID" id="19120160"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21998"/>
    <dbReference type="HOGENOM" id="CLU_091395_0_0_1"/>
    <dbReference type="OrthoDB" id="3800116at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="229" mass="25315" checksum="26F99826DB4D8065" modified="2014-04-16" version="1">MPHYNTPVYYPISSPSHGLPSDEYKHLKRQQEKSHLQRHLSKKHILPPPPSSSSFPSPSPSPSYPPSSYSSNSSFPPTPSSSSSFPSSSYSSSYHPTSPYPQTPYQQRNLPHAQRVHISAVKNATRKALASVFDAYDAYDGVCEAWPRSRYDGNNSNSNVYGCVRSRGDVDEYYERSKGRGEKRGSGESMRVGYHNMGYGGYGYGYGKGEDFGGPRLGSKFSFDSLDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTC7</accession>
    <name>W6ZTC7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_21798</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682667.1">
        <property type="nucleotide sequence ID" value="XM_007684477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTC7"/>
    <dbReference type="STRING" id="930090.W6ZTC7"/>
    <dbReference type="GeneID" id="19120122"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13873">
        <property type="entry name" value="CuRO_2_AAO_like_2"/>
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    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="Cu-oxidase_2nd"/>
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    </dbReference>
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        <property type="entry name" value="ascorbOXfungal"/>
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        <property type="entry name" value="FI03373P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
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    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
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        <location>
            <begin position="20"/>
            <end position="634"/>
        </location>
    </feature>
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        <location>
            <begin position="51"/>
            <end position="163"/>
        </location>
    </feature>
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        <location>
            <begin position="174"/>
            <end position="329"/>
        </location>
    </feature>
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        <location>
            <begin position="422"/>
            <end position="555"/>
        </location>
    </feature>
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        <location>
            <begin position="589"/>
            <end position="634"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="634" mass="70654" checksum="7B2262B1D798C9F1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU11</accession>
    <name>W6ZU11_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="2" type="ORF">COCMIDRAFT_90983</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="entry name" value="Hotdog Thioesterase"/>
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    </dbReference>
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        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="89"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="193" mass="21170" checksum="814E50C9FA90A3E2" modified="2014-04-16" version="1">MDEVTPRISSVPWAAALINDPNWKLISTFSRTPKSSGEDGFFGKTLKTDSTIRTFLSFLPTQEAEGDLPFLETRTILDLGPDLDGYPKTAHGGFQAALMDELCGVIVTQNRDAKVEKAQKLGQAVKAPDYYTAYLNTTYKKPLPTPGLLFCTAKVDRVEGGDRKIFIRTTLEDGNGTVYTTAEGLFVKLAVKL</sequence>
</entry>
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    <accession>W6ZUI1</accession>
    <name>W6ZUI1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUI1"/>
    <dbReference type="STRING" id="930090.W6ZUI1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_376"/>
    <dbReference type="eggNOG" id="KOG3085">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF1">
        <property type="entry name" value="HAD FAMILY PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC51164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="285" mass="31286" checksum="780461338D2704DF" modified="2014-04-16" version="1">MSVPSKPPKAILFDIGGVVVVSPFQAILDYEIENKIPVGYINYAIQKGPHDTGAWQLIERGEVELNDDWFASFKQQLSRPEIWSEYLQKLAKQQSIGGGQAVAGGTAAVPNIDAKRLFWRMMKISRTPDPYMYPALRKLGESGKFVLGAFSNNVIFPTGILDDEGTLFTKEIVHAPPPNPYANDSVDITSFFDVFLGSAAVGVRKPDPEAYKLAVREMDKIAKKKGMGEVTAGDTLFLDDIGINLKFAKKTGLRTIKVNLGKTREAVMELEAAVGIPLLDQKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWQ1</accession>
    <name>W6ZWQ1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_87986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685251.1">
        <property type="nucleotide sequence ID" value="XM_007687061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWQ1"/>
    <dbReference type="GeneID" id="19127175"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87986"/>
    <dbReference type="eggNOG" id="ENOG502SWZV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158092_1_0_1"/>
    <dbReference type="OrthoDB" id="5428081at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="91" mass="10278" checksum="4F514A400830F6EE" modified="2014-04-16" version="1">MATLQTVRRWIMTGAVAAITITGTIYGAGLKGQQEIKQQKRQILQATPEERIAQLEVTRSDLVLKKNEMERKIAMIVEKRRAKEQGQADGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZXA3</accession>
    <name>W6ZXA3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ras-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_87281</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685099.1">
        <property type="nucleotide sequence ID" value="XM_007686909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZXA3"/>
    <dbReference type="STRING" id="930090.W6ZXA3"/>
    <dbReference type="GeneID" id="19127025"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87281"/>
    <dbReference type="eggNOG" id="KOG0395">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_9_2_1"/>
    <dbReference type="OrthoDB" id="265044at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00876">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001856">
        <property type="entry name" value="RAS small monomeric GTPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="25428" checksum="1A3DFE392EE565A7" modified="2014-04-16" version="1">MDENNRITITVCGDGGCGKSSITLRLVRSEWTSEYDPTIEDSYSVTRTIDGVPYYLMLTDTAGQEEYRGLWAASNLQSDAFLLVYDITAANSLDALDYFMEMIDMETDNRLDNGKIPPIKCVVGNKCDLQGQRVIEAKKGLEWARNRKCGFMETSAREMVNIEETFALLVRRVVEARRLTANENAANRTAALPMSNANLSGPHTYSEKHDSDEPRQTFWSKLKCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0V0</accession>
    <name>W7A0V0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="9">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_22651</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="9"/>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683732.1">
        <property type="nucleotide sequence ID" value="XM_007685542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0V0"/>
    <dbReference type="STRING" id="930090.W7A0V0"/>
    <dbReference type="GeneID" id="19120292"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22651"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_1_2_1"/>
    <dbReference type="OrthoDB" id="7786253at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF111">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="10">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="218" mass="23445" checksum="18420CC3771F4B03" modified="2014-04-16" version="1">MELRRQLKPSGLFFPVDAGPSAMIGVMVGTSFSGTNAVRYGTMKDNVINPIIVLVDGSVIKTRYRPRKTTASYNLTSFFIDSKGTLGIVTEATLKLAAIPAETKVGFATFPLVRDASTAATAILWTGIQTGAMRIMDAVNRTGGTDRKWGVMPTMLLRFIGSPGQIAETTRQFSEMAISNGGGTLQFASTAEEQASLWAARKQALWSVLSLREGDEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJP6</accession>
    <name>W6YJP6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_111142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
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                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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    </evidence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Grimwood J."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
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                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
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        <property type="project" value="TreeGrafter"/>
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</entry>
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    <accession>W6YMM1</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055530">
        <property type="entry name" value="DUF7104"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23397">
        <property type="entry name" value="DUF7104"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="16929" checksum="29F1FB572068C9E5" modified="2014-04-16" version="1" fragment="single">ITEVVVKAAASNTSSGKDFMTLLLSRQDADIPITEAVIEAAAANDGSGKDVMKLLLDRWGAKIPITEAVLKAAASNHSSGTDIVTILFDRRGTDIQITETVTEAAAANDVNGTEVMKVLLRRRGAHVSITEAVVKTAARNTNKNVMTLLLDWREEEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPC2</accession>
    <name>W6YPC2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_10393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964364">
        <property type="protein sequence ID" value="EUC39520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693962.1">
        <property type="nucleotide sequence ID" value="XM_007695772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPC2"/>
    <dbReference type="STRING" id="930090.W6YPC2"/>
    <dbReference type="GeneID" id="19118408"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10393"/>
    <dbReference type="eggNOG" id="KOG1840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_15_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="341" mass="38123" checksum="74D52C7B2C377600" modified="2014-04-16" version="1">MKALFRIHQLVHTEFVWWLERHGEREKWPGAAAARAEAPGPFDEHGRKQVRSAYLQHAISATGLVNSVPGGTRTLLLEAIGQYQKRLGQYGPVETTYPIASSLSTEILGPEHPFTLMNRSRLGLVLNSQGKHKEAEEINRQTLAQYKKVLGPEHPDTLTSMSNLALVLNSQGKYKEAEAMNRHTLALRETVLGPKDPDTLMSMNNLAGALSSQGKYDKAEAMYQQTLALREKVLGPEHIDTLTSMSNLAGILKSQEKYDKAEAIHRQTLALREKVLGPDHLDTLTSVYCLAYILAKQHHVEEPLCLYQRAYAGYDSILGKGHPAALVCHQYYDDLRSLQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPJ6</accession>
    <name>W6YPJ6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Epoxide hydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_111176</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964324">
        <property type="protein sequence ID" value="EUC39580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693902.1">
        <property type="nucleotide sequence ID" value="XM_007695712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPJ6"/>
    <dbReference type="STRING" id="930090.W6YPJ6"/>
    <dbReference type="GeneID" id="19119725"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111176"/>
    <dbReference type="HOGENOM" id="CLU_1927227_0_0_1"/>
    <dbReference type="OrthoDB" id="6431331at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC39580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="131" mass="15265" checksum="322A93279F1D7DF4" modified="2014-04-16" version="1">MYKPWPYEIDIDLAFLEQTSSRVANFRSTADIAAPAWFDGPPSSNISTIAAYWSEKYDRLSDQKRLNEEFDHYTTTVPPPGDDYTDSLDIYFIHQRSEKSDAIPFLMLHRWPFTSLEWEKVIPELPKPSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ83</accession>
    <name>W6YQ83_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_8737</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964096">
        <property type="protein sequence ID" value="EUC41582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691898.1">
        <property type="nucleotide sequence ID" value="XM_007693708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ83"/>
    <dbReference type="STRING" id="930090.W6YQ83"/>
    <dbReference type="GeneID" id="19127048"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8737"/>
    <dbReference type="eggNOG" id="KOG2177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_295973_0_0_1"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16568">
        <property type="entry name" value="RING-HC_ScPSH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15898">
        <property type="entry name" value="BIFUNCTIONAL APOPTOSIS REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15898:SF13">
        <property type="entry name" value="BIFUNCTIONAL APOPTOSIS REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="112"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="345"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="646"/>
            <end position="672"/>
        </location>
    </feature>
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    </feature>
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        <source>
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    </evidence>
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        <source>
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        <source>
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            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41582.1"/>
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    </evidence>
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        <source>
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        </source>
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    <sequence length="1133" mass="123831" checksum="D0719FF7C39A257E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR66</accession>
    <name>W6YR66_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
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        <name evidence="7" type="ORF">COCMIDRAFT_29351</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">ATCC 44560</strain>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="799" mass="88917" checksum="115001BB5523E61C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRC3</accession>
    <name>W6YRC3_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">DUF7730 domain-containing protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_9981</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="22"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="280" mass="31598" checksum="CE46C66A647BF1E0" modified="2014-04-16" version="1">MALQYPQTGTTPPWTQSRNQDDTAIGFLDLPRELRDLVYDFAFRIQGALLIYTRDPTAARLVARAMNIQHAGRGPSAPQPLVNGALPVALLRTCRQLNAESSPILYSANVFSSWNARLLELSLAHRNLLVRHIVMEASPRGIFDRSLEHVKYCWKNRFWPEILKSGKALLDCFPNLESLTFSLKPPRGDELWRPGFFAVGGNKTREQRVGIVALWMSLGCCWADADQGLKACLHLEMGRQPARIARGEFVGSKFAPEEEEDDGVWDYTEFADAFDRMKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRY1</accession>
    <name>W6YRY1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_9724</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964169">
        <property type="protein sequence ID" value="EUC40390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693088.1">
        <property type="nucleotide sequence ID" value="XM_007694898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRY1"/>
    <dbReference type="GeneID" id="19129017"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9724"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF27">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="31"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC40390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="521" mass="56805" checksum="8EFDD520BEFD8B8B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSZ0</accession>
    <name>W6YSZ0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964148">
        <property type="protein sequence ID" value="EUC40658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692830.1">
        <property type="nucleotide sequence ID" value="XM_007694640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSZ0"/>
    <dbReference type="GeneID" id="19128570"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9505"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122062_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019626">
        <property type="entry name" value="Stress-induced_KGG_rpt"/>
    </dbReference>
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        <property type="entry name" value="Stress/Virulence-Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36569">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36569:SF5">
        <property type="entry name" value="CONIDIATION-SPECIFIC PROTEIN 10 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10685">
        <property type="entry name" value="KGG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="11051" checksum="4D1D6E43C89BD282" modified="2014-04-16" version="1">MASSNPANFANRPKDELREIAAKGGHASHGSSHNDSSSNDHPGRNPDGTFTKGSEVAKELGAQGGHASHGSGDSGSHTHKDSGRNPDGTFKKGSELASELGSQGGHASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTN8</accession>
    <name>W6YTN8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Queuine tRNA-ribosyltransferase catalytic subunit 1</fullName>
            <ecNumber evidence="6">2.4.2.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_9247</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>guanosine(34) in tRNA + queuine = queuosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:16633"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:18571"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:194431"/>
            <dbReference type="EC" id="2.4.2.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.64" evidence="6"/>
    <dbReference type="EMBL" id="KI964128">
        <property type="protein sequence ID" value="EUC40955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692508.1">
        <property type="nucleotide sequence ID" value="XM_007694318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTN8"/>
    <dbReference type="STRING" id="930090.W6YTN8"/>
    <dbReference type="GeneID" id="19128085"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9247"/>
    <dbReference type="eggNOG" id="KOG3908">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022060_1_0_1"/>
    <dbReference type="OrthoDB" id="10249838at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002099">
        <property type="term" value="P:tRNA wobble guanine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889401" description="Queuine tRNA-ribosyltransferase catalytic subunit 1" evidence="7">
        <location>
            <begin position="26"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="8">
        <location>
            <begin position="21"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="6">
        <location>
            <begin position="256"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="6">
        <location>
            <begin position="280"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="100"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="410" mass="45294" checksum="267C692B5FCA7E65" modified="2014-04-16" version="1">MTHASMHSALAFELLATCSVTRARAATLHLPHGPVPLPIFMPVATQASLKGLTPDQLEDQGCRLCLNNTYHLGLKPGQATLDSIGGAHKLQSWPHNILTDSGGFQMVSLLKLAKVTEEGVRFLSPHDGSPMLLTPEHSISLQNSIGSDIIMQLDDVIVTTSPDHARMREAMERSVRWLDRCIQAHKYPEKQNLFCIIQGGLDLEMRKECTVKMVARDTPGIAIGGLSGGEEKESYCKVVKTCTELLPQKKPRYVMGVGYPEDLVVSVALGADMFDCVWPTRTARFGNAITSRGSLNLRNAIYSEDFSPIEEGCNCTCCRPASAGGLGITRAYIYHVTAKETAGAHLLTMHNVYYQLNLMKLVREAIIEDRYPQFLKDFFNKLYNGQKDNYPRWAVDALRGVNVDLLSNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU64</accession>
    <name>W6YU64_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_107141</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964122">
        <property type="protein sequence ID" value="EUC41068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007694237.1"/>
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    <dbReference type="STRING" id="930090.W6YU64"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="3364892at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF26">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G07710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="151"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC41068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="407" mass="45689" checksum="6312F9C782E307CC" modified="2014-04-16" version="1">MTAGSSVRAGVSVRSDGPSDGAPDTPQAPNKAPATGVQAAGMRAVAARMVAFYFRAPVKAFFRGRIDYMGYARAINPHVMADAKWSWRMTTPAVLAHAIRTEGWGFIPKQVLPPLMANTCIGAVLYTTYLHSLSALHEPSSYQTKRVYPPPPPSVTFTAGLIGGGIQSVFAAPFDALQTRFRTADILEGKHKTMWHYAGYKLRSIGLQGIFAGWTLSFLKDAFGAAVFFGTFETVKSQAYLEFVSHYYGSRSRDTLLESSIPYLQEDYDDRPVIRPHYMLEPMFLLLAGISASVTSQLIQHPLMEVQDVHYRRLEALDFQAHQDNKPSHIVRRYYHAYEETFAQCKVLAKRAGGWRNYLYRDFFMSTIKQTPSTAAGLIVFEIVRRKYSFENEEVMINHEDARILLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVD2</accession>
    <name>W6YVD2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_100959</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964030">
        <property type="protein sequence ID" value="EUC43392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690084.1">
        <property type="nucleotide sequence ID" value="XM_007691894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVD2"/>
    <dbReference type="GeneID" id="19117773"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100959"/>
    <dbReference type="eggNOG" id="ENOG502TAYJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048470_0_0_1"/>
    <dbReference type="OrthoDB" id="61113at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="46"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="334"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="475" mass="51925" checksum="D90E4F592E53C8DB" modified="2014-04-16" version="1">MTAAPVSVASLRNHPDNANLPTSNQPATIIGTTVAFLSIAFITLSLRMWIRIKDRLWGWDDCFVVLAGIASFCGDVLVCIMPGDGLGLHLWTLDAKHLMLYFKHIYSTNAAYCASATLIKLSILFQYLRVFAESAPSATTNGYRLARRLTWMMIVICTLWGLTFFLLAVFPCRPIAKNWNMNLPGRCIGWGAKDPSKFFPMFLGHSVSNLVLDAMVLLLPLPFVTALRIAGKSRAGLIGLFILGSAVVLVALGRLIALTVNRAGTIPMLDMSFHTPVVYIFAVLEVNFAIITASIPIFWPVIATLASNKIFVVNEVEIRVEDIARHESFDSNGAISLTDRKDTPSGDSKTGMVSTILDHIPRRSGEKISSGNHARGSSAASSIHQPMGTGFVGRKGSNASTIGRPFAELGSRPSQDSSRHLYQISSKDQSSRNLTKNDGDDWFAEMDRVNPHGPVTTTVQKTSVPFEHIKAFDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVL4</accession>
    <name>W6YVL4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_8726</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964096">
        <property type="protein sequence ID" value="EUC41568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691894.1">
        <property type="nucleotide sequence ID" value="XM_007693704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVL4"/>
    <dbReference type="GeneID" id="19127018"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8726"/>
    <dbReference type="eggNOG" id="KOG0748">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029962_0_0_1"/>
    <dbReference type="OrthoDB" id="5585746at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF97">
        <property type="entry name" value="ADIPOR-LIKE RECEPTOR IZH3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="505" mass="57160" checksum="32BDB24C8A6743C9" modified="2014-04-16" version="1">MARSNSSVGVSSAVMTSQEEPIQPSYRGYGTFASQRPAQRQRRHSWHTRPCMQEAENFQVLLRNFLTELNCRLDLLEDYGHLKYDAGVEYAYNTLLAVRESCSKISDGAIEAGRRQASVFVETLEERYKDALERKETLGEKVLEGIVLMDNYLTEFEARAFALGDASIGTYAHEFYEEGRRKMDEGIEIAKGVVDGGLDKARRARENIELRVEHAVQRALAQAKAHGLIQYEDLPEPWRVNPHILKGYRFQEGKWACVRSIFGLHNELINIWTHLLGFVMVLAIAFYFYPSSANFSMSTKADIFIAAVFFFAACKCLACSTIWHTMNSISHQTLLERFACVDYTGISLLVAASIMTTEYAAFYCEPVSRWSYMCITALLGVGGVILPWHPTFNRADMAWLRVVFYCSLALTGFLPFGQLAYTRGVAWAQYFYAPITKSLLVYVTGACLYASKTPERFFPGLFDYIGCSHNIWHVAVLGGIVFHYMAMQTMFTQALTRAQTSCSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVP2</accession>
    <name>W6YVP2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_56790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964095">
        <property type="protein sequence ID" value="EUC41598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691888.1">
        <property type="nucleotide sequence ID" value="XM_007693698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVP2"/>
    <dbReference type="GeneID" id="19124699"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_56790"/>
    <dbReference type="eggNOG" id="ENOG502S67X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041445_1_1_1"/>
    <dbReference type="OrthoDB" id="3205825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="33091" checksum="5C73A35F055444C7" modified="2014-04-16" version="1" fragment="single">MINNNGLPPGYKAWGPFISKNYTIHPVSQSDLILAGTAFGIANIFGLSAAFIGFRQTRASRQPWKNTYIWMIWLELAASVVLSVVCLLFLLRVIRPSFYMYMGICNPVVCWVVQIQVLPQIIVNRIRVVLPDRQRGTYLAIGTAVIVTLINISVFCVWMPARLQISQRWIRINSIWDRIEKVLFLLLDAYLNWYFIKTVQSELVRNGLSKYNRLVRFNKRIIVVSLLLDVMIIAAMSIPNGFVQVTTNLSNPYVKLTSSSYAIFHPLAYLAKLNIEMSMAHFIRTIALAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVQ7</accession>
    <name>W6YVQ7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_8675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964093">
        <property type="protein sequence ID" value="EUC41630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691838.1">
        <property type="nucleotide sequence ID" value="XM_007693648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVQ7"/>
    <dbReference type="STRING" id="930090.W6YVQ7"/>
    <dbReference type="GeneID" id="19126923"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8675"/>
    <dbReference type="eggNOG" id="KOG1127">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1051909_0_0_1"/>
    <dbReference type="OrthoDB" id="421075at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039226">
        <property type="entry name" value="Ski3/TTC37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040962">
        <property type="entry name" value="TPR_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704">
        <property type="entry name" value="SUPERKILLER 3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704:SF7">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18833">
        <property type="entry name" value="TPR_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="287" mass="32424" checksum="D0E013FB4C264887" modified="2014-04-16" version="1">MSTKTALKAAKAAIGAKDWEEAKNQAKAVIDKDPDNYFAYLFLGRANDGLSKFDEAAKAYYKATKIKPEDPQAWLGLRAMYEGLKGAKVDENIDVGLTLAQIYMDLDDLQKSQSAIDKLVDHARAHGTKMQYARALNTQLPSSPVYTYLEGRLPDPAKVYSRIAEIHETHDAATIKRLVEERRLRVGATLEGTTAAVKNEVYAASPLEDIYEQATNWTRDDELRREYEEKLLARAYDTLMVLPAGQKAEKREKVMRLAHDMVVIKHPNLLAWTIELEWRSGMEIEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW38</accession>
    <name>W6YW38_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_110710</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964263">
        <property type="protein sequence ID" value="EUC39739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693739.1">
        <property type="nucleotide sequence ID" value="XM_007695549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW38"/>
    <dbReference type="GeneID" id="19119646"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110710"/>
    <dbReference type="eggNOG" id="ENOG502SIYQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_0_1"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF151">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="38"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC39739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="362" mass="39385" checksum="D01D0E26F7688CA3" modified="2014-04-16" version="1">MFEAVVQHRSRHDTSDRGPQLRDTTTALLVLAFVFVALRFIARSKRGLSYGADDWMIVVSLLICFVAGGLNYAMIHWGLGRHAITLPPDNVTMVLKLLVAFECVYCTAVGLVKLSLLVMYLRLFPTNSFRIGSYILGFVTIAWVIAINFVSIFQCTPVKKAWLGPAIDGTCINLKASFIGNAVPNILTDVAILCMPVAQVLKLQVTTAQRASLLFMFLLGGFVLCASAYRFVTVMQFNVTDTTGTLATACTWCVVEVASGIISACLPTLRPLMLLISSQFSSTRNRSENELVTGGRSSKTQLVTIGGTGTKRNQDFERLKDDFEVHSGFAAAHTHGSHGDASSSIDERAIVGAIYGQELKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWA3</accession>
    <name>W6YWA3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_8525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964085">
        <property type="protein sequence ID" value="EUC41813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691661.1">
        <property type="nucleotide sequence ID" value="XM_007693471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWA3"/>
    <dbReference type="GeneID" id="19126632"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8525"/>
    <dbReference type="HOGENOM" id="CLU_1106941_0_0_1"/>
    <dbReference type="OrthoDB" id="3694162at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889290" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="26330" checksum="04EFF80428DE57B9" modified="2014-04-16" version="1">MQLSLMTLVLLAPTQAIASELTRVATSEPTQVTKVTVKTSTISIPPEFTQASIVAQLQKDSILPAPSNPAWIEPSWLLYSDTTPTETSIAAATEAAVSAEAETAAATPTAKPDNWNSNPKDDKIHVMIFLGITGGLFGLMVSLGLLGSCVQAHQRRARAKKASGSSSNNDQTRDVERAAGLAGIFKGDANNSSRTLVAGEAAQQGGVVIMMPEFPAPAYRNNISPQDVHYPQGEAVSQAQRGSASMRPTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWB9</accession>
    <name>W6YWB9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 13 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_29429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964083">
        <property type="protein sequence ID" value="EUC41850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691620.1">
        <property type="nucleotide sequence ID" value="XM_007693430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWB9"/>
    <dbReference type="STRING" id="930090.W6YWB9"/>
    <dbReference type="GeneID" id="19121504"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29429"/>
    <dbReference type="eggNOG" id="KOG0471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_1_1_1"/>
    <dbReference type="OrthoDB" id="1740265at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033934">
        <property type="term" value="F:glucan 1,4-alpha-maltotriohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004574">
        <property type="term" value="F:oligo-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000025">
        <property type="term" value="P:maltose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11333">
        <property type="entry name" value="AmyAc_SI_OligoGlu_DGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.400.10:FF:000001">
        <property type="entry name" value="Maltase A3, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000064">
        <property type="entry name" value="Oligo-1,6-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000087">
        <property type="entry name" value="Oligo-1,6-glucosidase IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF232">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 13 CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="6">
        <location>
            <begin position="27"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="598" mass="69188" checksum="72C25910A2D9DB3C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWG6</accession>
    <name>W6YWG6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_51989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964081">
        <property type="protein sequence ID" value="EUC41905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691588.1">
        <property type="nucleotide sequence ID" value="XM_007693398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWG6"/>
    <dbReference type="GeneID" id="19124527"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_51989"/>
    <dbReference type="eggNOG" id="ENOG502SSYN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043317_0_0_1"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF56">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="81"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="409" mass="46644" checksum="7C0D3C746F0ABD94" modified="2014-04-16" version="1" fragment="single">EPFETLQHKIAAVAALCFEQDVSSIRVEHMKGGSYNRVAALTISPRPKRTRLTWFHALLQTLFPSWYQGALQTSESPDSKSYIIRILRFEGEDEDFGVNRDVAILKTVGALLDLPIPTVVSYDPTSNNAMGKPYMIQSRLPGKNLAALMNEKTLNIEQLKCIAKRVTELVPKIAAVEGPGGAIPLNALSSDSTQLQVESLHLQHDKLGDKLFRLPDEPQDTYEHLLEQCRRWSEYHRENSYFTFGEIWCNFGRIVQSLDERGFLEGPCVLAHRDLMAYNLLAEVRSNTDVEITGVIDWDSALMVPEFVAYRAPFWLWTEDHIASDIADDEIMVNTSPHSETCKILKQVFLDNASEKFKRFAFSPEAMLARRMYVIIKEGIASDWYMDEAWDIVRDWHLLHPDDGIQLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX57</accession>
    <name>W6YX57_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_104424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691396.1">
        <property type="nucleotide sequence ID" value="XM_007693206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX57"/>
    <dbReference type="STRING" id="930090.W6YX57"/>
    <dbReference type="GeneID" id="19118499"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104424"/>
    <dbReference type="eggNOG" id="ENOG502S1U7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041813_0_0_1"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="572" mass="64281" checksum="207F47FE2C1918C9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXE3</accession>
    <name>W6YXE3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_109439</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964188">
        <property type="protein sequence ID" value="EUC40194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693289.1">
        <property type="nucleotide sequence ID" value="XM_007695099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXE3"/>
    <dbReference type="GeneID" id="19119431"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109439"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYD6</accession>
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        <recommendedName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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</entry>
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            <taxon>Dothideomycetes</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="4">
        <location>
            <begin position="23"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="3">
        <location>
            <begin position="230"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="5">
        <location>
            <begin position="575"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="661" mass="75762" checksum="4B4B97FA42D2B4E5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ65</accession>
    <name>W6YZ65_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964136">
        <property type="protein sequence ID" value="EUC40829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692644.1">
        <property type="nucleotide sequence ID" value="XM_007694454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ65"/>
    <dbReference type="STRING" id="930090.W6YZ65"/>
    <dbReference type="GeneID" id="19123962"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40890"/>
    <dbReference type="eggNOG" id="ENOG502SFZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056399_2_1_1"/>
    <dbReference type="OrthoDB" id="9997739at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="5"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="309" mass="35448" checksum="BC3949941658211F" modified="2014-04-16" version="1">MIQSELFIFNVGKGDGKKSIAVHSKAVATKSAYFWALMNNGMAESRERTVEYTDIEPEDFARFVEYAYRHDYTTPSWVHEKTHMEDQALPVQETVIAIREPITRSIVDIGPILIDPHRQPSSTSRLGQPSLENRWENWGSDKISKKKKKSKPEGVVNLRAGFNKLSYLTSSEPQAAMLAAFKPQYNTAVDQDFTPVFLAHARLYTFACMRGVDPLKRLTLHKLHQTLVGFQLYMRRASDIVELARYAYRQGDDRKDDGTKDELRQLVLEYIVCEVTTFGKHPAFLDLLHEGGEFVVDFWSLAYKEEFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZN3</accession>
    <name>W6YZN3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_101888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964041">
        <property type="protein sequence ID" value="EUC43043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690433.1">
        <property type="nucleotide sequence ID" value="XM_007692243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZN3"/>
    <dbReference type="GeneID" id="19117958"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101888"/>
    <dbReference type="HOGENOM" id="CLU_717611_0_0_1"/>
    <dbReference type="OrthoDB" id="3542716at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="384" mass="43396" checksum="C47B6DC9C44A4368" modified="2014-04-16" version="1">MADIKLTRKARYETAEAQILDLSFTIEGAAFEHPDVFDNSKPVFINARKASSIMYKKAIAKWEENPNGPKSRETLELTAAETAQEIEEDMERYLLVGWVPQTQQQPGKVVRRYGRPVGIDRPEEDKIITFDKDEDDLPLMVVVKSLDEEVKLASVFKYVLLEQVDGLCTPYSINSKEVYHLSLYRDMTTMNHKRLAAWNQLACKYAYQGHKKPEVWNTKRSQATRDREMAVPPPNKDSGNDVDATSTEDMLEDNASYSSEMADVPSDISEDLSCDSDKIRELQAFVDAANKENAPFTQAQADVMVEEAQVLWSNAQHLDSYHVYLLAQGMREVGLAPAYPHLKAFVLEGCYHIAKMSGEVTIEELGAIALQAEETVKRVLSYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZV3</accession>
    <name>W6YZV3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Triosephosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_7410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690353.1">
        <property type="nucleotide sequence ID" value="XM_007692163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZV3"/>
    <dbReference type="STRING" id="930090.W6YZV3"/>
    <dbReference type="GeneID" id="19125280"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7410"/>
    <dbReference type="eggNOG" id="KOG1643">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024251_2_3_1"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC43118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="255" mass="27020" checksum="C4B8E334AE84FBBC" modified="2014-04-16" version="1">MPPIARPRRIVGVSLKMYFDLPSTLSYIRGVLQLDGDAWNARTDLFVIPDFVSLTESARILESSSIILGAQDTFWEDKGAYTGEVSPLVLRQAGARIVEIGHAERRALFGENDETVAKKAGAAARNGLIPLVCIGEKTHHGVASAAVGAAVDECTPQVKSVLAAVPDDTEVILAYEPVWAIGAKEPADPDHVVMVTKALRSLAAGRKGLTRIVYGGSAGPGTFAKIADGVDGLFLGRFAHDLHNLKKVIEEVGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1I4</accession>
    <name>W6Z1I4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Luciferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_38510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964025">
        <property type="protein sequence ID" value="EUC43573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689910.1">
        <property type="nucleotide sequence ID" value="XM_007691720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1I4"/>
    <dbReference type="GeneID" id="19123486"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38510"/>
    <dbReference type="eggNOG" id="ENOG502S21Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063954_1_0_1"/>
    <dbReference type="OrthoDB" id="5358398at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048273">
        <property type="entry name" value="Luciferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040841">
        <property type="entry name" value="Luciferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17648">
        <property type="entry name" value="Luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase" evidence="2">
        <location>
            <begin position="156"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="234" mass="26414" checksum="E07FCF5FD91A76B8" modified="2014-04-16" version="1">MASRYLLAGITAAGLIFWYDFKSWQSTGGTPPTLQGYLKIRRWGLYLLYSRQNLLDPSPIPDSGESYLKPEKVQNRQGPRPGLTRWTLPQRQVPENITAGASAALHNLMQEFASTAPYNEYIDTRPSKTEGGTGPAIYVKEGVKTINPVAHKIFYEVAHVHPAENSLHVYVSPQDAKLVMKRGWGQRFPVTWIAPPSWIMVYAPRNEDEVEIVREIVRAAVCHAVSMNIYEDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z210</accession>
    <name>W6Z210_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BYS1 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_99297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964013">
        <property type="protein sequence ID" value="EUC44025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689449.1">
        <property type="nucleotide sequence ID" value="XM_007691259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z210"/>
    <dbReference type="STRING" id="930090.W6Z210"/>
    <dbReference type="GeneID" id="19129442"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99297"/>
    <dbReference type="eggNOG" id="ENOG502SP0S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083650_1_1_1"/>
    <dbReference type="OrthoDB" id="3682664at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006771">
        <property type="entry name" value="CetA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36195:SF4">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36195">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01990)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04681">
        <property type="entry name" value="Bys1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887092" description="BYS1 domain protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="16107" checksum="80DCB9BB305050F0" modified="2014-04-16" version="1">MYFIIPTLLALASSATAAGIAVVLNNSPKPIYVWSVGSSVGARNDIKAEGIYWEEMRRDEKTGGIAIKITNSADGLYSGAPQQVFAYNLDNDTVWYDLSTVFGDPFAGYRLQVTGDNGGSILWPKGTHPGGSQLKSAPSEGNIFFSIDPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2I9</accession>
    <name>W6Z2I9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689551.1">
        <property type="nucleotide sequence ID" value="XM_007691361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2I9"/>
    <dbReference type="STRING" id="930090.W6Z2I9"/>
    <dbReference type="GeneID" id="19125053"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6717"/>
    <dbReference type="eggNOG" id="ENOG502RXTA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014722_0_0_1"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF6">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1996" evidence="1">
        <location>
            <begin position="40"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="361" mass="39246" checksum="CB83B6EE9A8CD55E" modified="2014-04-16" version="1">MRFTPLLFAALAGAVPQFGNNQRFTMLRFGCAQSVIDRIDPLMNPGLAPSPHMHQIAGGNAFNTTMPSTDISKLASCTTCGYSEDLSNYWTANVYFKARNGTYKRVPQVPNRDLFNDKYTSKTTGGFVVYYVSGNKGDVTAFKPGFRMLVGDAANRVSKNRKSQTCFRCYTGPNFGGDNAAPCQDAKLDTEGFPTTPCPGGIRSNILYPTCWDGVNLDSPDHKSHVAYPTNGPALFTGTSTGGACPSNHPVRIPQLMLEIVWDTTKFNNKADWPADGSQPFFLSTGDNTGYGQHGDYVFGWKDNSLQKAMDDAKGCMGANCGSLKTQQPADGNKCVVPNRVPEERDGWMKALPGMDGMPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2T1</accession>
    <name>W6Z2T1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_104780</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.2.9" evidence="1"/>
    <dbReference type="EMBL" id="KI964079">
        <property type="protein sequence ID" value="EUC41964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691542.1">
        <property type="nucleotide sequence ID" value="XM_007693352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2T1"/>
    <dbReference type="STRING" id="930090.W6Z2T1"/>
    <dbReference type="GeneID" id="19118569"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104780"/>
    <dbReference type="eggNOG" id="ENOG502S329">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030506_1_0_1"/>
    <dbReference type="OrthoDB" id="2017317at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003839">
        <property type="term" value="F:gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017939">
        <property type="entry name" value="G-Glutamylcylcotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935:SF0">
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            <end position="250"/>
        </location>
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            <position position="134"/>
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    </feature>
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        </location>
        <ligand>
            <name>substrate</name>
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        </location>
        <ligand>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="349" mass="38629" checksum="8F2B6CDB1063B044" modified="2014-04-16" version="1">MLAFDPIPQTSQARLDASLPDAPLDIATLLAHPPTPTSEKPKTVLYLAYGSNLCNETFRGARGIRPLSQVNVVVPSLRLTFDLPGVPYKEPCFANTARRIPSAQEHHKDAWHKGLVGVVYEVTLSDYAHIIATEGGGSAYADILVDCHVLDKGKDTVPTTPTSKPFKAHTLFASQEDNERIVRPDPSYAQPSARYLKLIRDGALECELPGEYREYLHGIRPFRITRKKQAVGQALFLSIWMPFVLFVFALGKKFSDEKGRAPAWLAKLTAMVFSGMWTSYDAVFKPVFGEGERTVGDEALGAMDQSIWEALSTRQDAEKEGLLEESVHTMYTAQMAVQRPSRGDDVESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2X8</accession>
    <name>W6Z2X8_COCMI</name>
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        <recommendedName>
            <fullName evidence="11">SMP-LTD domain-containing protein</fullName>
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    </protein>
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        <name evidence="12" type="ORF">COCMIDRAFT_4736</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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        </location>
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            <end position="80"/>
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        </location>
    </feature>
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    </feature>
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        </location>
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        </location>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="933" mass="101698" checksum="4E36756CD4DD1F37" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z324</accession>
    <name>W6Z324_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="930090.W6Z324"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_99091"/>
    <dbReference type="HOGENOM" id="CLU_1704078_0_0_1"/>
    <dbReference type="OrthoDB" id="3762642at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="163" mass="19133" checksum="37FEF0502021C316" modified="2014-04-16" version="1">MTNLIQGKTKESRYKSLSAGEQTRIAVRKMRQVTGTFMYMRDKDIAEIFAKEKNRIGKMIGHIDRELPKTPKVMKSGQSCTSWQTQDLEKKGVDFMDFNLKALNQEWDSQRKTDEFKSDAKDDKATQDRKQMLKATHKGIIELIKKTEDAWDKVKNWEKPKDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z329</accession>
    <name>W6Z329_COCMI</name>
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        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_93683</name>
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    <organism evidence="11 12">
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS4 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007689188.1"/>
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    <dbReference type="STRING" id="930090.W6Z329"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_93683"/>
    <dbReference type="eggNOG" id="KOG3301">
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    </dbReference>
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    <dbReference type="OrthoDB" id="1697570at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
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    </evidence>
    <sequence length="192" mass="22137" checksum="0ED563253A9CE0F2" modified="2014-04-16" version="1">MAPRSYSKTYSVPRRPFESARLDTELKLVGEYGLRNKREVWRVQLTLSKIRRAARSLLTLDEKDPKRLFEGNALIRRLVRVGVLDESRMKLDYVLALKIEDFLERRLQTCVYKLGLAKSIHHARVLIRQRHIRVGKQIVNVPSFMVRLDSQKHIDFALTSPFGGGRPGRVRRKKAKAAEKGDGDDAGEEDEE</sequence>
</entry>
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    <accession>W6Z364</accession>
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        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
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    </feature>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="35416" checksum="1271CBBFB30C66D0" modified="2014-04-16" version="1">MHSANDAYVNIHDHGREDKERPPWYWRLIAIAASWMILAGYLILPGLYAKDAQLRFTQAVLSVFVVALLTAGYSFTALLCFACRDKHFQAENVFLPALASSAFGLISIAYNFLSSRAYHWGLSATSGTVLSAVTTLTYTVLCIITFRAANKPPPRQHPDARANLWSEQSYYNNFATNMYPTAMRPADHPPAVIYTEDDRVNQQMALLLHKSDSRPSPDANSTFRIDLPEDPDQHDRELHSQELVGTPVQAHSEWQRGRGHSRPDSLGEQQAWMQLHERGRSANRAESAGGQSSHSRNLSREERRRQIEMGDLHT</sequence>
</entry>
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    <accession>W6Z3B4</accession>
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        <recommendedName>
            <fullName evidence="9">CAP-Gly domain-containing protein</fullName>
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        <name evidence="10" type="ORF">COCMIDRAFT_37727</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <subcellularLocation>
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            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CLIP1_ZNF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF93">
        <property type="entry name" value="RESTIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16641">
        <property type="entry name" value="CLIP1_ZNF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
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    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
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            <end position="440"/>
        </location>
    </feature>
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        <location>
            <begin position="97"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC44455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="731" mass="79213" checksum="D76B6D5118804998" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3B9</accession>
    <name>W6Z3B9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_25664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687207.1">
        <property type="nucleotide sequence ID" value="XM_007689017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3B9"/>
    <dbReference type="GeneID" id="19120805"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25664"/>
    <dbReference type="HOGENOM" id="CLU_413297_0_0_1"/>
    <dbReference type="OrthoDB" id="10687464at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="664" mass="72263" checksum="E4F0366D82070101" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3E3</accession>
    <name>W6Z3E3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">magnesium chelatase</fullName>
            <ecNumber evidence="1">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_4648</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="1"/>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687201.1">
        <property type="nucleotide sequence ID" value="XM_007689011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3E3"/>
    <dbReference type="GeneID" id="19124321"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4648"/>
    <dbReference type="eggNOG" id="ENOG502QQMN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034390_0_0_1"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052041">
        <property type="entry name" value="Nucleic_acid_metab_PIN/TRAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11603">
        <property type="entry name" value="AAA FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11603:SF132">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ChlI/MoxR AAA lid" evidence="3">
        <location>
            <begin position="236"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="331" mass="36252" checksum="763A66F96F4DC2E9" modified="2014-04-16" version="1">MDDADPMAEKVQSLSDLELAVLICLVAEQHCVIECEMESLRGVQVELELVAAKVFGLTCAVLECEEGMSLDEFGRGILVDGEEGDGGRIANVVVARDLNRASEQVQVQALELIRGKRNFTRTAVHAAPKPFLFVALNAADSPRLTMHLNDQFFISHRHQVEDGLPNLEELQEKERGFDDASSMSSVVRTIPFMAGKHKPQSALFTSEDLANLAKLTAGVKISSEVRAYLYNIVVFMRLHRAVAGGVSALATRHFSILAHTLAPLHGLDYMSPSMVALAARKIYPHRIVITAPENERSMQWGSSLEAVKAVLEGVTPEDVIEEVLESVEVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4A8</accession>
    <name>W6Z4A8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_103399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964060">
        <property type="protein sequence ID" value="EUC42459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691010.1">
        <property type="nucleotide sequence ID" value="XM_007692820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4A8"/>
    <dbReference type="STRING" id="930090.W6Z4A8"/>
    <dbReference type="GeneID" id="19118293"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103399"/>
    <dbReference type="eggNOG" id="ENOG502QVFK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029872_0_1_1"/>
    <dbReference type="OrthoDB" id="10071171at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01830">
        <property type="entry name" value="XynE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053140">
        <property type="entry name" value="GDSL_Rv0518-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784:SF3">
        <property type="entry name" value="GDSL FAMILY LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784">
        <property type="entry name" value="GDSL-LIKE LIPASE/ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="183"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="403" mass="43407" checksum="24E18F2AA9153D22" modified="2014-04-16" version="1">MPQLTEPANLPPAPFNQTGAVFVNSTVRQTLYVTTDANQIRLKFTNVFGGSNLPITAVTVALPANQTAGIYDIQPQTLQKVTFGGEDGISVPNGALAVSDPINFPIKAQQVITVTMYLAAGQRTNSITSHPGSRTTSWWQFGNAVSAPSLAITNPATQSAAHWYFISSIEAWVPQNVGSLLIIGDSITDGRGSTTNKNDRWPNLLLARLQKNPATKSISVGNLAAGGNRILADGLGPNAFGRVDRDVLAHPGVKYAMIFEGVNDIGSAPPTPDVQNQIYASLVQAYKQMVSLIHAHGIPVFGATITPFSAPSNFTGQPYSNPEREKTRQRINEFIRTSGVFDAVVDFDKFLADPKIPSQLAPQYDSGDYLHPGPVGYAHLAEQFPVEIFAKWKNGADEFNFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5W3</accession>
    <name>W6Z5W3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Guanine deaminase</fullName>
            <shortName evidence="8">Guanase</shortName>
            <ecNumber evidence="8">3.5.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Guanine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_35307</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>guanine + H2O + H(+) = xanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:14665"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; guanine degradation; xanthine from guanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.3" evidence="8"/>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686328.1">
        <property type="nucleotide sequence ID" value="XM_007688138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5W3"/>
    <dbReference type="STRING" id="930090.W6Z5W3"/>
    <dbReference type="GeneID" id="19122753"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35307"/>
    <dbReference type="eggNOG" id="KOG3968">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_0_0_1"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="UniPathway" id="UPA00603">
        <property type="reaction ID" value="UER00660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008892">
        <property type="term" value="F:guanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006147">
        <property type="term" value="P:guanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000022">
        <property type="entry name" value="Guanine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014311">
        <property type="entry name" value="Guanine_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02967">
        <property type="entry name" value="guan_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF6">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="79"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="484" mass="53042" checksum="6287B8B3AC94C846" modified="2014-04-16" version="1">MAASTPIPRTIYFGPFVHSISLSTLEIEPHGAIGVDSSGIIRFVNRDVESLASLLSSLDTAWTDAKVVSISETSNGFFFPGFIDTHVHAPQHPNTGLFGKTTLLDWLQKYTFPTESSFSDIKRAYRVYNNFVSRTLSHGTTTAAYYATIHVPATNTLADICLERGQRALIGRVCMNSDLSPEYYRDTSVDQSYLDSKSSIEYIRSIDPKGSIVKPIITPRFAPSCTPDCLSAMGRLAQETDAHVQTHISENKGEIELVKSLFPDSKSYADVYDTHGLLTDKTILAHCVHLTPEERRLILARKSKISHCPASNTAITSGCAPIRSLLDEGHTIGLGTDISGGFSPSILENVRQAIWVSRHLCIQTSSDAVKLSTEEALYLATRGGAAVVGLQDTVGGFEVGKEWDAQMISLGAVGEFGSEAGAFEEGPVDVFGWESWQDRVEKWVYSGDDRNTLAVWVRGRLVHCTERYPYRKEVGYAPSKGCTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z653</accession>
    <name>W6Z653_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_96171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688272.1">
        <property type="nucleotide sequence ID" value="XM_007690082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z653"/>
    <dbReference type="GeneID" id="19128801"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96171"/>
    <dbReference type="HOGENOM" id="CLU_076163_1_1_1"/>
    <dbReference type="OrthoDB" id="5289641at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39697:SF2">
        <property type="entry name" value="CYANOVIRIN-N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39697">
        <property type="entry name" value="RICIN B LECTIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="20624" checksum="9627CC40EE3F254B" modified="2014-04-16" version="1">MAHDQPTTHSFVGSETWDIPTPSASSEDTTQNASRSEIPPSSIPWPGRAYIIKSRKSGQVITFLDGEVVMDRIGGLGTFRWRCVEDKGWLGFKDPASAHCLGYQEHGILFCRFPHHRNNERIFPRMRPEGGYVLLVRHDDHLRPLGVFTNESKNGTKQKIKIMDWSSEEIVWDFIEASVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6F1</accession>
    <name>W6Z6F1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="5">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="5">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Translation initiation factor eIF3 p33 subunit homolog</fullName>
            <shortName evidence="5">eIF3 p33 homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF35</name>
        <name evidence="9" type="ORF">COCMIDRAFT_7416</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690355.1">
        <property type="nucleotide sequence ID" value="XM_007692165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6F1"/>
    <dbReference type="STRING" id="930090.W6Z6F1"/>
    <dbReference type="GeneID" id="19125282"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7416"/>
    <dbReference type="eggNOG" id="KOG0122">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034595_0_0_1"/>
    <dbReference type="OrthoDB" id="639027at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071540">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3e"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002188">
        <property type="term" value="P:translation reinitiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd12933">
        <property type="entry name" value="eIF3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000328">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037949">
        <property type="entry name" value="Transl_init_eIF-3_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="203"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="282" mass="30886" checksum="5F5CA749AE9DAB3E" modified="2014-04-16" version="1">MSRPAGRTDWAEEDDEESLTSLPPNQVIKNKDGTETVISYRIEDGKKIKTTRRIKKTVVKQVVNPRVAERKQWAKFGQEKGKPPGPQTDTVSVAENIVFRPVSNWKASTEDKGDEAKKKAELKNAKIKCRICQGDHFTTKCPFKDTMAPEGDVAPADMPDDAPGVGASGGLGAGSGGYVPPHLRGRGGAGEKMGGKFDRDDSATLRVTNVSEFAEEQDLRDMFSRYGHVTRVFLAKDRETGRAKGFAFVSYADRSDAAKACEKMDGFGFGHLILRVEFAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6Z4</accession>
    <name>W6Z6Z4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_35039</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686010.1">
        <property type="nucleotide sequence ID" value="XM_007687820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6Z4"/>
    <dbReference type="STRING" id="930090.W6Z6Z4"/>
    <dbReference type="GeneID" id="19122694"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35039"/>
    <dbReference type="eggNOG" id="KOG0423">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_658869_0_0_1"/>
    <dbReference type="OrthoDB" id="10069349at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000077">
        <property type="entry name" value="Ubiquitin conjugating enzyme E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="4"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="160"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="299"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC47512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="417" mass="46019" checksum="4912911DDFC8BB83" modified="2014-04-16" version="1">MNSKSLRRLAADHGSLHTAGLPPNYLFAPESDDAADLTSLDILLAGPVGTPYAGGVWRLHLDIPPTYPAAPPTAQFRTRLWHPNIDEATGAVCVETLKRDWSSTLKLRDVLVTISCLLIQPNPASALNEAAGKLAVEDWDGYCRRAKLMTEIHAAIPSSIAKEVREAQMRGEERTTESEPQSEPQPQPTAKLHSKGKEKERVKITPAGPRLQRRPSEDEENRRRRAATHDADSDPESDWIPGPVKTSKVPGRHESNIFGIKGLDDTMQLDTPPKRIFAAQNLPKDKGKAKGATDDSDPFLTTTTAPQKSISRPVTRSFDLAPPPPALATSTRPAEPSHPTGNEESDNSTTLLLRDFSLSWHDTFALHNNDPDAKKRIASPEFEAKAKWEMKRFRQAAWDLEKFNRGEFGPRVGVGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7B9</accession>
    <name>W6Z7B9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TATA-box-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_94399</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBP family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687649.1">
        <property type="nucleotide sequence ID" value="XM_007689459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7B9"/>
    <dbReference type="STRING" id="930090.W6Z7B9"/>
    <dbReference type="GeneID" id="19128441"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94399"/>
    <dbReference type="eggNOG" id="KOG3302">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060161_1_0_1"/>
    <dbReference type="OrthoDB" id="2127950at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04516">
        <property type="entry name" value="TBP_eukaryotes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000001">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000002">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033710">
        <property type="entry name" value="TBP_eukaryotic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="27280" checksum="24745AEDB7B6CBA7" modified="2014-04-16" version="1">MDPNSLTSHPSTAAQAQTFVAPGSLSYPQGANLDMTAPSTEHNTQQVAENANGVATPAATPDTQNGQVPSGIVPTLQNIVATVNLSARLDLKTIALHARNAEYNPKRFAAVIMRIREPKTTALVFASGKMVVTGAKSEDDSRLASRKYARIIQKLGFSAKFTDFKIQNIVGSCDIRFPIRLEGLASRHHTFSSYEPELFPGLIYRMMKPRIVLLIFVSGKIVLTGAKVREEIYQAFELIYPVLSDFRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7U6</accession>
    <name>W6Z7U6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_93882</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963972">
        <property type="protein sequence ID" value="EUC46080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687434.1">
        <property type="nucleotide sequence ID" value="XM_007689244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7U6"/>
    <dbReference type="GeneID" id="19128347"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93882"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016134_0_0_1"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF3">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="379"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="602"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC46080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="716" mass="80315" checksum="54236EC3785B67BB" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z891</accession>
    <name>W6Z891_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10 13">Catalase</fullName>
            <ecNumber evidence="3 10 13">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_25885</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 13">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10 13"/>
    <dbReference type="EMBL" id="KI963973">
        <property type="protein sequence ID" value="EUC46008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687460.1">
        <property type="nucleotide sequence ID" value="XM_007689270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z891"/>
    <dbReference type="STRING" id="930090.W6Z891"/>
    <dbReference type="GeneID" id="19120840"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25885"/>
    <dbReference type="eggNOG" id="KOG0047">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010645_3_0_1"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000003">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821:SF1">
        <property type="entry name" value="CATALASE-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 13" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 13" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="16">
        <location>
            <begin position="42"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC46008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="740" mass="83180" checksum="B54B44AE646C42B9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8C5</accession>
    <name>W6Z8C5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_25765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687284.1">
        <property type="nucleotide sequence ID" value="XM_007689094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8C5"/>
    <dbReference type="GeneID" id="19120819"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25765"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_1"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196:SF1">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="31420" checksum="BBC3CA8AE5678C03" modified="2014-04-16" version="1">MVDLDFRFRQPSSSLTKHNDTYPFIDPSKYARAHTGKTVVVTGGGQGLGKAIALAFANAGADIAIIGRSQQPLLATASEIEAKGRKCIAIPGDVTDSAFVNRAVAECVGRFSTLAADDMSKWWGVFELNVRAVAEMAHATLPIMFARGKGIIFNIASDSGIIGIPFTTAYSSSKSAVIKLTEVLSWEVASKGIRVYAIHPGTVATGFAGDQIVNHEEVATNSSMKWMLDMKGEFQEDTPELSANGLVALADMGESEVKALNGRYINLTRDVGELIEGVKAGKLGDSTALLTMKEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8L7</accession>
    <name>W6Z8L7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964205">
        <property type="protein sequence ID" value="EUC40036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693438.1">
        <property type="nucleotide sequence ID" value="XM_007695248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8L7"/>
    <dbReference type="GeneID" id="19129577"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9998"/>
    <dbReference type="eggNOG" id="ENOG502S9N5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065416_2_1_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="49"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="289" mass="31588" checksum="835BDB45B967CDE6" modified="2014-04-16" version="1">MTSSEPSMNTLYSSFASKYEISSGGCTRQLATHLLSLLPPLSNQSHIHDNACGPGILAQELLFQNPSLHPAITCTDSSPQMISLARQTVPTIITPSGAANLSFHILPGDALGPLPSNSFTHSITNMGIFFFADPLRGAAEIHRTLTPTGTAIVTTWKAAGYMPILHRAQKAVRPQDPLFEWPIAKEWYEAEHLREILRKAGFGSVEMSEVTVHFAGRSLEETCGFLVDMWRQVGPKWTEDEYAEFGKQLIVEGSKEAVTTKRAVNGKKDAEIMEVVGFPMVAHVAVAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z966</accession>
    <name>W6Z966_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_93184</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963968">
        <property type="protein sequence ID" value="EUC46308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687172.1">
        <property type="nucleotide sequence ID" value="XM_007688982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z966"/>
    <dbReference type="STRING" id="930090.W6Z966"/>
    <dbReference type="GeneID" id="19128218"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93184"/>
    <dbReference type="eggNOG" id="ENOG502S7YC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069176_1_0_1"/>
    <dbReference type="OrthoDB" id="1630758at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15898">
        <property type="entry name" value="BIFUNCTIONAL APOPTOSIS REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15898:SF13">
        <property type="entry name" value="BIFUNCTIONAL APOPTOSIS REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
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            <begin position="19"/>
            <end position="85"/>
        </location>
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        </location>
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            <begin position="252"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="305" mass="34607" checksum="CCA1D11073E13390" modified="2014-04-16" version="1">MAQTMPAAPPEDVAHDHLCPICQLLLYTPVKTQCNHLLCASCMAQWADASSTNQIEHSSLDVHLADFDPNYDPSYDLEANCPMCRTHTTASPDKPLARQLEAMYPVTYAERRVEEEVDRGSRIGQDGVEGVMILIGNKHRLIRNPVSANEHLWTFFVRTSRPELIKEVHIYLHPTFRPSHHVLRTAPYEFEAQGWGFFTIESKIVLKAPYNWIIDNAGTKKQGLELSWTLDFEGRGRQGRVRAKVKKFEAETAPAGRTLRSRHIPPTTEPEVDNSNEDGDEDSSEDNVEDEGDSEFIVPSRRSRR</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </feature>
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            <begin position="134"/>
            <end position="173"/>
        </location>
    </feature>
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            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <begin position="163"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="173" mass="19012" checksum="3CEAF08E2EB673C9" modified="2014-04-16" version="1">MPPVLFPIPPRLSSVLSRPATAELRADATPPRADILNEDSWQEIFPLQSIFSRPSGRGSPWSQMTTTSPQSSPYLRDLQGHSRKGSNTSVASTASVALERCMARLQAGFDARRMTPISPFSTAFPAPLRIRKSPSLPPGTWMRRPSTASQVGLKELETDKKLPPTPFPFETPE</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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            <dbReference type="EMBL" id="EUC46600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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            <taxon>Pleosporaceae</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="eggNOG" id="KOG1768">
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    </dbReference>
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    <dbReference type="OrthoDB" id="10262653at2759"/>
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    </dbReference>
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        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="40S ribosomal protein S26"/>
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    </dbReference>
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        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
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    </dbReference>
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        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="122" mass="13815" checksum="F4AC01B5423CACF7" modified="2014-04-16" version="1">MVKKRASNGRNKKGRGHVKPIRCSNCSRCTPKDKAIKRFTIRNMVESAAIRDISDASVFPEYTVPKMYLKLQYCVSCAIHGKIVRVRSREGRRNRAPPPRVRYNKDGKKINPNQAAAKTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAC7</accession>
    <name>W6ZAC7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_86387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
        </source>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="184"/>
            <end position="454"/>
        </location>
    </feature>
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        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48692.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="566" mass="63724" checksum="FF7A69457CC93DE6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAK1</accession>
    <name>W6ZAK1_COCMI</name>
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        </recommendedName>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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    <dbReference type="OrthoDB" id="3037908at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="C6 FINGER DOMAIN TRANSCRIPTION FACTOR DBAA-RELATED"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
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        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="578" mass="66067" checksum="767EBC7438026998" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAZ2</accession>
    <name>W6ZAZ2_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_35291</name>
    </gene>
    <organism evidence="2 3">
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="83" mass="8923" checksum="43EE4643403B2B24" modified="2014-04-16" version="1">MSREQDSVKMSASLVAQHHAAKVTTKASSGTPEVRSMSNKTLSFKSVGRTHVVGYASEAFEEDQTLHSGEETTCAKHTMVPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB15</accession>
    <name>W6ZB15_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684565.1">
        <property type="nucleotide sequence ID" value="XM_007686375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB15"/>
    <dbReference type="STRING" id="930090.W6ZB15"/>
    <dbReference type="GeneID" id="19126774"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85966"/>
    <dbReference type="eggNOG" id="KOG0747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053163_2_0_1"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08946">
        <property type="entry name" value="SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103:SF6">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="305" mass="34332" checksum="3774B70D410B2B21" modified="2014-04-16" version="1">MSSLGKRIVFTGGSGKAGRHVIPYLLQQGYSVLNLDLIDFPDPDAGVFTLKTDLTDSGQVFNALTTHFNFAGYEAPHVPGPPDAVIHFAAYARNMLVPDNECYAGNVRSTYNVIEAACKLGVRKIIIASSETTYEVCFGQGNLDYTAFPLVEDADVNPMDTYAISKLCGERVARGFARRFDADIYALRIGNVIEPHEYARDFPKYIQHPETRKRNAWAYIDARDLGQICHLCVQKDGLGFQIFNATNDTITATFPTKQFLEQYAPNTPITREMGEWEAPLSNRKIKEVLGFKEEHDWRKYYNPDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBM5</accession>
    <name>W6ZBM5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_90268</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686103.1">
        <property type="nucleotide sequence ID" value="XM_007687913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBM5"/>
    <dbReference type="STRING" id="930090.W6ZBM5"/>
    <dbReference type="GeneID" id="19127650"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90268"/>
    <dbReference type="eggNOG" id="ENOG502SK0G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046574_1_0_1"/>
    <dbReference type="OrthoDB" id="93019at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051178">
        <property type="entry name" value="TfdA_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779:SF2">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT XANTHINE DIOXYGENASE XAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779">
        <property type="entry name" value="DIOXYGENASE RV0097-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="27"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="395" mass="44716" checksum="B08C7287618B15DF" modified="2014-04-16" version="1">MSPARLALESNFEVKEMTKNIDEKYNFGAVVEELDLGNISDAEVKALSEAIWIHKLVVVKGQKNLTPIKQWELVTRFDPKAPQFHSHGDVKTFSKQGGLLSKGRDVLGIPGAENVRLIGKGYQGEDHYGLKDVTLKKGILHVWHVNVPTNEEYEAGHTRFQRWHIDAPLYARDPAWFTTLRCIKRPTAPALTIHWDDGSGQTMETEPGLTAFISNVQTYDMMTPEEKNLADHSWVEYAPYPYQWMSDCKGHPNGLGVVSQGKEKHLADLPPYDEKNIKRCPMVWLNPLTHERAFMVHGICVRRAFFRSSPHGESTVVDDVAAIRDWLRPIQERVLKPEYVLLPRVEEGDVVMWANYQLFHSAVDYPDHWGARCMHQANIGASEGPKGPVPVPDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBV0</accession>
    <name>W6ZBV0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_29988</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964115">
        <property type="protein sequence ID" value="EUC41191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692280.1">
        <property type="nucleotide sequence ID" value="XM_007694090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBV0"/>
    <dbReference type="STRING" id="930090.W6ZBV0"/>
    <dbReference type="GeneID" id="19121600"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29988"/>
    <dbReference type="eggNOG" id="ENOG502SM0C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090039_1_0_1"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF37">
        <property type="entry name" value="OXIDOREDUCTASE MDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="260" mass="28292" checksum="807EFC61A09F911B" modified="2014-04-16" version="1">MPRYAILGATGRTGQALLSALLSRPQAQIHAFCRNKRKLADAFPDLDSMKQMTVFEGSITDTDIVATCVQACQVIFLVVSTNDNIPGCRMSQDTVLAVLAALEGQKKRGSTISPKLVLLSSCTVDEHLSRHTPWLLRQILLLSASQVYHDLMEAEKLLRAQESWLTTIYMKPGALAVDKARGYALSFTDEDSPVTYEDLAGAMIEAAEDEGGVYDGRNVSVVNTNGKPAFPKGTPLCIVVGLMRHFFPVLHPYLPTGLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC64</accession>
    <name>W6ZC64_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_89887</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685952.1">
        <property type="nucleotide sequence ID" value="XM_007687762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC64"/>
    <dbReference type="STRING" id="930090.W6ZC64"/>
    <dbReference type="GeneID" id="19127569"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89887"/>
    <dbReference type="eggNOG" id="ENOG502S0UJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015417_2_0_1"/>
    <dbReference type="OrthoDB" id="5430812at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="505"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="541"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="598" mass="68810" checksum="78B121DF9D1461C6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC66</accession>
    <name>W6ZC66_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_106481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964109">
        <property type="protein sequence ID" value="EUC41321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC66"/>
    <dbReference type="GeneID" id="19118869"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106481"/>
    <dbReference type="HOGENOM" id="CLU_1895824_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="134" mass="15371" checksum="79992A05F5764C2D" modified="2014-04-16" version="1">MVVILRLKWRRVTSPARLGAKMAQSVFYSYLDVRPTSSFAHLTQNPVHPSSIPSEKGAYVVTFKDQVFKQKRPLRRAHANWQYCTLLTMPLGSHQSTYYGFLFSKCIAQYVDHISHGRTRRPRFRGSSVAPSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC99</accession>
    <name>W6ZC99_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_40441</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC41366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692107.1">
        <property type="nucleotide sequence ID" value="XM_007693917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC99"/>
    <dbReference type="GeneID" id="19123878"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40441"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="8120565at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF20">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="40"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC41366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="568" mass="62254" checksum="AB90802B03F06DEE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCD1</accession>
    <name>W6ZCD1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_64937</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684001.1">
        <property type="nucleotide sequence ID" value="XM_007685811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCD1"/>
    <dbReference type="STRING" id="930090.W6ZCD1"/>
    <dbReference type="GeneID" id="19124973"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_64937"/>
    <dbReference type="eggNOG" id="ENOG502SX9X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_45_11_1"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC49462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="126" mass="13720" checksum="1126A130FDB3E44F" modified="2014-04-16" version="1" fragment="single">VRLLLRMRLGIESEEDCEALVLHDTVRESRKELLQFMLDAGADINAQGGPYGNALQAATHTSKVEIVKVLLDAGADVNAQGGHYGNALQAARHRRTSMYRDDEMGIIVKMLLNAGAEDTDQDGEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCX7</accession>
    <name>W6ZCX7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_96014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688202.1">
        <property type="nucleotide sequence ID" value="XM_007690012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCX7"/>
    <dbReference type="GeneID" id="19128769"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96014"/>
    <dbReference type="eggNOG" id="ENOG502S1CW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051938_4_3_1"/>
    <dbReference type="OrthoDB" id="2094269at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="267" mass="30061" checksum="8D04B56EF8C92754" modified="2014-04-16" version="1">MQTAPIRAALEDFEWVFVQGTVRHTEGNWSLHTSDFSKLPLYTYYNPFDPQSIIQTHEELLDIIRSHGPFDGVFAYSGGAALAAELLIEAARSESAVEPLFRFAVFVNGASPLRVFKVDDVDTVSGHVDVSQTFQQAKEMFLRPSALRHKPGVSEEDQVDHKKLLGLLSRLEGKMMADGTAFLSDGTYGLCRWEQNKLQPALIEIPTLHVRSTAEDHTDPHHGKHLVELCDQFDVEEIHHEFGHDFPRGRQLMKQIADAIRDMAELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDM2</accession>
    <name>W6ZDM2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_88453</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate 4-semialdehyde (L-ASA) by the reductive dephosphorylation of 4-phospho-L-aspartate. Mediates the second step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-aspartate 4-semialdehyde + phosphate + NADP(+) = 4-phospho-L-aspartate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:24286"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685457.1">
        <property type="nucleotide sequence ID" value="XM_007687267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDM2"/>
    <dbReference type="SMR" id="W6ZDM2"/>
    <dbReference type="STRING" id="930090.W6ZDM2"/>
    <dbReference type="GeneID" id="19127273"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88453"/>
    <dbReference type="eggNOG" id="KOG4777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049966_1_0_1"/>
    <dbReference type="OrthoDB" id="1894490at2759"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009090">
        <property type="term" value="P:homoserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18130">
        <property type="entry name" value="ASADH_C_arch_fung_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02315">
        <property type="entry name" value="ScASADH_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000200">
        <property type="entry name" value="Aspartate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000016">
        <property type="entry name" value="Probable aspartate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051823">
        <property type="entry name" value="ASADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005676">
        <property type="entry name" value="Asp_semi-ald_DH_pep-lack"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00978">
        <property type="entry name" value="asd_EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006416">
        <property type="entry name" value="PRK08664.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718:SF1">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000148">
        <property type="entry name" value="ASA_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdehyde dehydrogenase NAD-binding" evidence="15">
        <location>
            <begin position="17"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="14">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00050041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000148-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC48095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="370" mass="40144" checksum="4467922B7F8B4A85" modified="2014-04-16" version="1">MDAEHFTSPKKEFPKKKCGVLGATGSVGQRFILLLALHPHLELHAVGASERSAGKKYKDAVKWKQALPYSERIGELVVKKCVPEEFKDCDLVFSGLDSDVAGDVEMAFLKAELAVFSNAKNYRRDPLVPLVVPTVNLPHLDVIKHQRQHHKLEKGFLVCNSNCAVIGIVIPFAALQDKFGPINQVSVVTMQAVSGAGYPGVSSMDIIDNVVPFISGEEDKLETEASKILGSVNEGVTGFVDQPMKISAACNRVPVLDGHTACVSLRFERRPPPSAEEVKQAMRDYVSDAQKLGCPSAPKKAIAVMDEPDRPQPRLDRETDRGYTVSVGRIREDESGIFDIKFVALSHNTVIGAAGSSILNAEAAVLKGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDQ3</accession>
    <name>W6ZDQ3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exoribonuclease phosphorolytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_1368</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683494.1">
        <property type="nucleotide sequence ID" value="XM_007685304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDQ3"/>
    <dbReference type="STRING" id="930090.W6ZDQ3"/>
    <dbReference type="GeneID" id="19119848"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1368"/>
    <dbReference type="eggNOG" id="KOG1069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063514_2_2_1"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11372">
        <property type="entry name" value="RNase_PH_RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="7"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC49962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="258" mass="28152" checksum="1B16DB911F6B09A3" modified="2014-04-16" version="1">MVVPTVTLTHLNRADGSATYTHNGYSIIGAVNGPIEVQRRDELPEEAAIEVNLRPAAGVGSPRERHLETLVHNTLRSIILTQSIPRTLVQITLQVRSLPEEDSTAGVNTSLSLLPHLLHTALLALLSASIPLSTTLTSIIVAQPTSPSSALLSPTANQLLRAKPIRSVHVFAFSGKRKMLLSESEGSFSYEDWNEACQMAEEACCGEDDSEDQGGIKLDVEGDVMDIDAQAEAESLEKWLRSVVKRKVEHEQRWRSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE84</accession>
    <name>W6ZE84_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_2969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685303.1">
        <property type="nucleotide sequence ID" value="XM_007687113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE84"/>
    <dbReference type="STRING" id="930090.W6ZE84"/>
    <dbReference type="GeneID" id="19121552"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2969"/>
    <dbReference type="eggNOG" id="KOG0005">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010412_6_4_1"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031386">
        <property type="term" value="F:protein tag activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01806">
        <property type="entry name" value="Ubl_NEDD8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000023">
        <property type="entry name" value="NEDD8 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038738">
        <property type="entry name" value="Nedd8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="77" mass="8661" checksum="35A1F7F44997F735" modified="2014-04-16" version="1">MQIKVRTLTGKEIELDIEADYKVSRIKERVEEKEGIPPAQQRLIYGGKQMNDDKTAADYQLEGGATLHLVLALRGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEB5</accession>
    <name>W6ZEB5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Early meiotic induction protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687618.1">
        <property type="nucleotide sequence ID" value="XM_007689428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEB5"/>
    <dbReference type="STRING" id="930090.W6ZEB5"/>
    <dbReference type="GeneID" id="19123028"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36443"/>
    <dbReference type="eggNOG" id="ENOG502S4MN">
        <property type="taxonomic scope" value="Eukaryota"/>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="901"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="935"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="991"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1048"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1274"/>
            <end position="1285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1285" mass="137046" checksum="244FD53FB463ABF6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFT6</accession>
    <name>W6ZFT6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rhomboid protease</fullName>
            <ecNumber evidence="4">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_93066</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S54 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="4"/>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687129.1">
        <property type="nucleotide sequence ID" value="XM_007688939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFT6"/>
    <dbReference type="STRING" id="930090.W6ZFT6"/>
    <dbReference type="GeneID" id="19128197"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93066"/>
    <dbReference type="eggNOG" id="KOG2632">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084816_0_0_1"/>
    <dbReference type="OrthoDB" id="10257275at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF1">
        <property type="entry name" value="RHOMBOID PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="11">
        <location>
            <begin position="60"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC46379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="262" mass="29389" checksum="853C785950DCB0CE" modified="2014-04-16" version="1">MPAPSLPQLNPARIRSYILRLPFCTKVVVAAIVGLWIATIPFPWIRDVGRLEPAKMDFTQMHRLNLFPVLHWNFIHMIFNLFAVTPLIERFESEYGTLVTLALFTGPFGTIPGGVYTLLEKFVLRSNTAVMGASVWVFLLLSAEVMKTQKTNPYFSVGPYKIPTWTTPLILIVITSILVPYVSLVGHLCGAGLGYLWATGYIKFLVPHEKILRWIETKLNLLGRLPHYVSVDQKTYGRYGVLPTTGIPLGPRSPDVAQRLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFX4</accession>
    <name>W6ZFX4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="4">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_2436</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + H2O = 2 phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684692.1">
        <property type="nucleotide sequence ID" value="XM_007686502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFX4"/>
    <dbReference type="STRING" id="930090.W6ZFX4"/>
    <dbReference type="GeneID" id="19120577"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2436"/>
    <dbReference type="eggNOG" id="KOG1626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040684_0_2_1"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.80.10:FF:000004">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="241"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC48778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="288" mass="32542" checksum="5C65936BA959884F" modified="2014-04-16" version="1">MSYTTRKIAAANTLEHRIFIEKDGQLVSPWHDIPLYANEQQTILNMVVEVPRWTNAKMEISKEEPLNPIKQDIKKGKLRYVRNCFPHKGYLWNYGAFPQTWEDPNVVHQETKAKGDNDPLDVCEIGELVAKPGEVIQVKVLGVMALLDEGETDWKIMVINVNDPLAPKLNDVEDVERHLPGLLRATNEWFRIYKIPDGKPENQFAFSGECKNKKYAMDIVRECAEAWEKLITGKTPKDEISLTNTTVSNSPDRADSGSLNIPAGENKAPAPIDPSIDKWFYISGAPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGJ9</accession>
    <name>W6ZGJ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="8">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_21669</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the glycosyl hydrolase 62 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="8"/>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682522.1">
        <property type="nucleotide sequence ID" value="XM_007684332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGJ9"/>
    <dbReference type="GeneID" id="19120100"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21669"/>
    <dbReference type="eggNOG" id="ENOG502QR18">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041805_0_0_1"/>
    <dbReference type="OrthoDB" id="3156236at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08987">
        <property type="entry name" value="GH62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005193">
        <property type="entry name" value="GH62_arabinosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40631:SF2">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40631">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE AXHA-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03664">
        <property type="entry name" value="Glyco_hydro_62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 8 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889816" description="Alpha-L-arabinofuranosidase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="358" mass="39478" checksum="AFD67709BF79851B" modified="2014-04-16" version="1">MRSFLLAGAAFAASVLARSLPLHEHAALETRQNNGGLPSTFTWSSSGILVSPKQDSRQIQGIKDPTIIQNNGVYHVFASTAKEAGYNLVYFNFTDFSQANQAPFFYLDQSGIGTGYRAAPQVFYFAPQKLWYLVYQNGNAAYSTNPDISNPRGWTAPQVFYPNGTPQTIQNGLGSTGYWVDMWVICDTALCHLYSSDDNGGLYRSQTPVSQFPRGMNEPVVTLKAAKNDLFEASTVYNIANSSTYLLVVECIGTGNSPGGLRYFRSWTTQSLTSDRWTPLAATQQTPFLGAANTQFPAGRWSQSLSHGELIRTNVDQRLQVRPCEMRYLYQGIDPNASGSYNALPWKLALATQTNSKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIB3</accession>
    <name>W6ZIB3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Centromere protein Cenp-K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_32946</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-K/MCM22 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683768.1">
        <property type="nucleotide sequence ID" value="XM_007685578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIB3"/>
    <dbReference type="GeneID" id="19122214"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32946"/>
    <dbReference type="eggNOG" id="ENOG502RXW1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048926_0_0_1"/>
    <dbReference type="OrthoDB" id="9445768at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020993">
        <property type="entry name" value="Centromere_CenpK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14401">
        <property type="entry name" value="CENTROMERE PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14401:SF6">
        <property type="entry name" value="CENTROMERE PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="246"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC49730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="40177" checksum="2EB85FA993D92A80" modified="2014-04-16" version="1">MIQAPDQTIQRIQKYAQEARNLHNDAVDFDASDTETRLAQTVKELQARVEEQQAALDQLRSQSNLDLDSIAYASEDPREKLQQLVAVKDAYKRLKPTATYLPPQGSLLPALLAARSIQQNVQGTKEAIASTQSQLLAKETALRREEANLHDANRLTQAMEDRIQRLRSQHQDRSQKTPAQLARELIAAKRAQKEHSDAEMQRLGEAMNDFINDYLSTMLAAEELGGPVVGDMLDVDDDTLAAGFTKKGRAKSSKKAPSDKTRQRRIDQIWGPTKPAVDQDDDGHEEEPPPTEAEAADAEMRRLMSDLFATLMGPGGGKAYVQLQRDSAASRFLVRAKIAQFHPKDANKLRLIDFGRELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIF7</accession>
    <name>W6ZIF7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_32949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683769.1">
        <property type="nucleotide sequence ID" value="XM_007685579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIF7"/>
    <dbReference type="GeneID" id="19122215"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32949"/>
    <dbReference type="eggNOG" id="ENOG502S78C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065192_0_0_1"/>
    <dbReference type="OrthoDB" id="5538558at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050563">
        <property type="entry name" value="4-hydroxybenzoyl-CoA_TE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793">
        <property type="entry name" value="4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793:SF39">
        <property type="entry name" value="THIOESTERASE_THIOL ESTER DEHYDRASE-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="32286" checksum="E7A95BE4B6582CDC" modified="2014-04-16" version="1">MPPLLRSIVCRVKPIRQLPGVQRVSFERYQSTSSDNAPATAALSPRWLSDVKLRIGKCISFGINPAQVEEAGSILQETAEDWRELVGGSEGFLTGKQWRGLYRQEVVWGEMGHVNNVMYNRYAESARVNWTLNFAASDPQHRAEWLELMTPKSIGLILRSIKTDYKFPMTWPDRITVLHKLRNKPSQGSDHFILDVMILSEAHRRPAARCVEDIVVYDYRTGRKSPLPPFMVEKFQETFNLQEQAKARNSGRVKALLDRVRALEKGSWDRPDAKEDFGSANDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIW4</accession>
    <name>W6ZIW4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glyoxalase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_83160</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683581.1">
        <property type="nucleotide sequence ID" value="XM_007685391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIW4"/>
    <dbReference type="STRING" id="930090.W6ZIW4"/>
    <dbReference type="GeneID" id="19126200"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83160"/>
    <dbReference type="eggNOG" id="KOG0813">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_4_0_1"/>
    <dbReference type="OrthoDB" id="515692at2759"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935">
        <property type="entry name" value="BETA LACTAMASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935:SF94">
        <property type="entry name" value="TENZING NORGAY, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="10">
        <location>
            <begin position="44"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="283" mass="31258" checksum="CD40DF6EF8D0E4E2" modified="2014-04-16" version="1">MNFLAASIKRSSLSSFVRPIAKRSSVPARAMHIQSIPMWEGTGNNYAYLVSDDKTKEAVIIDPAHPPEVLPVLKEQTTTGGLKLTKIINTHHHHDHAGGNTEILKAFNLPIIGGRDCEKVSTTPAHNETFNIGSINVKALHTPCHTQDSICFYFEDGNDRAVFTGDTLFIGGCGRFFEGNPEQMHKALNETLAALPDDTKVFPGHEYTKGNVKFAKTVLNNDAIKKLDTFSQENKQTQGKFTIGDEKQHNVFMRVTDPELQKVTGKTEPIDVMGALRAMKDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIZ0</accession>
    <name>W6ZIZ0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DUF221-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_90194</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686109.1">
        <property type="nucleotide sequence ID" value="XM_007687919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIZ0"/>
    <dbReference type="GeneID" id="19127633"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90194"/>
    <dbReference type="eggNOG" id="KOG1134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009187_1_0_1"/>
    <dbReference type="OrthoDB" id="2150324at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF149">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="488"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="606"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="664"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="688"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="11">
        <location>
            <begin position="38"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="216"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="10">
        <location>
            <begin position="394"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="828"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="263"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="828"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="867"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="950"/>
            <end position="961"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC47394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="975" mass="110589" checksum="F374C9C6FE4A2C84" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJH0</accession>
    <name>W6ZJH0_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_38329</name>
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    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="term" value="F:ubiquitin protein ligase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710:SF241">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
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            <end position="173"/>
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    </feature>
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        </location>
    </feature>
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    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC43736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="198" mass="22439" checksum="726CA14C311AFAE6" modified="2014-04-16" version="1">MSGYEVEHNISTKDDKPQQPPRRPDLSTFFSQLELVDTSDPRSHTNPNALPQPENMAAAFRLLANAFETMRGRPADEANAEGDLLASMIEILRENADDPPTELKGVPDSFLDELERVPKEKLKPSDTCPICVNPFLEDKYPLVVQLPCHDDHRFDLDCIGPWLKLNSTCPLDRKELLKKKQPPPPPVDDEEDYDDMYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK69</accession>
    <name>W6ZK69_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_44724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963947">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK69"/>
    <dbReference type="GeneID" id="19124246"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_44724"/>
    <dbReference type="HOGENOM" id="CLU_3111822_0_0_1"/>
    <dbReference type="OrthoDB" id="10354520at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="51" mass="6152" checksum="1A2EF62972E1539A" modified="2014-04-16" version="1" fragment="single">GYYAIKLRDQTKTPKVTGSKKPKYTTIVQDHRTNNLLKRIYSERKQTLKRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKB4</accession>
    <name>W6ZKB4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription elongation factor Eaf N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_38072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964013">
        <property type="protein sequence ID" value="EUC44026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689439.1">
        <property type="nucleotide sequence ID" value="XM_007691249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKB4"/>
    <dbReference type="STRING" id="930090.W6ZKB4"/>
    <dbReference type="GeneID" id="19123386"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38072"/>
    <dbReference type="eggNOG" id="ENOG502SEGQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_601261_0_0_1"/>
    <dbReference type="OrthoDB" id="125903at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019194">
        <property type="entry name" value="Tscrpt_elong_fac_Eaf_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09816">
        <property type="entry name" value="EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription elongation factor Eaf N-terminal" evidence="2">
        <location>
            <begin position="19"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="481" mass="51974" checksum="1AF0311E9EA2297C" modified="2014-04-16" version="1">MASPVVESRIEPHKKAHFTLHLSDRIRNTDDAVEYSSVKYNHKPTQTSDNRSTTLSAPSSTNTCSLRIDDTSESGDQDVFTFTGQKSQPKKSYVLILDPASQQATLEPLSSSYTFNLATRNGKDISSQHAKIYPKKLKNDAQDKDQDDDLFGEAAADDEGGDPDPDNPYDFRHFLSKEKAKRGDESDYRYASSPEHRAGTGSAAHTPQFGARAPPAAAPVRKPAAATAPKKRKTTTTNPMVKPKKAQPPPAVRLQRTATEPAAKPKGKSTAPPASKIKSAEVIHSSDESDGEIASSPAPPSPAPAQNQRHQHDEDEAEDDSDDDGGLEIEVPDARPPRRKNGALGARSLGHNLGAGYMRSPSNGPISLASAANSDVEGSPNPHARNRNTQDEIDFGDLGGGDAEGDDDDEEEEEDAEEYEYNDRDVEPMDIGPPVQPDTTSHDHKHGAIADIPADDDEDDLEELMRRGLEGGDSSEESEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL49</accession>
    <name>W6ZL49_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_27306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964006">
        <property type="protein sequence ID" value="EUC44331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689125.1">
        <property type="nucleotide sequence ID" value="XM_007690935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL49"/>
    <dbReference type="GeneID" id="19121100"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27306"/>
    <dbReference type="HOGENOM" id="CLU_672662_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="409" mass="43995" checksum="A13F4CD2868FDDFB" modified="2014-04-16" version="1">MVGRVARRRVLPRAGAIWQTGRPWKGNCVLAGLAAGTAGARHQGGLRHGGWSRRRGRQAGRQAACGSGRKGPRSGSREEQKGPKRWPTGPSTVSIGRRGTPRGAAEREKAEGEGGQRLGGGGRDWRLADLLSKKQRDEHMHAAFGSGGKRRRRGGGRIAERVPDHGLVWRKQCWILDRARQGTPGRAAGGCRRAAGSSKAVEEAKKPFGNIQEDELRVGEREGGPCSMLALHKAYICILGQARGTALANAASVGLGLCTTPTVRATHPLSPTSTARHSLHTLHSLHHARTAHQPPHLAASRSRAAVSPALASPTLQRIDAHANHGHAEHMHLHVFAQTARPKWRLALAHSRSASTLTLPHAEVIDTCQRTPFSAAIADTMVDRRPTARPLSRATGRWSRESYPTDPSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL52</accession>
    <name>W6ZL52_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_81488</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682946.1">
        <property type="nucleotide sequence ID" value="XM_007684756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL52"/>
    <dbReference type="GeneID" id="19125879"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81488"/>
    <dbReference type="eggNOG" id="KOG4169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_13_0_1"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="294" mass="32427" checksum="D6C6B8B886AB64F0" modified="2014-04-16" version="1">MPKKVALITGGASGIGFATAKALSNSSETWDIHIVDQNAEAGKKAVSELKNAFFHQADITGYQSLISAFEITWNKAERLDFVFANAGIVERDNFYAKHDLNGPPPPPPNKFSADINYKAAIDTSYLALHYFRKTKAKNGGDGFDPVLIMTASCGGLYPSEFCPIYSGSKAGLILFNRAIAVAYHDEGIRTSTICPGTIKTALMTEEEWKFFPTEYFTPVETVSDTVMQLVEGAEMKDAKGITKSKNEIWGLTVEVNGNNFYFRDGPEYCDDNMKEMMTNTSMKKQLARIEGKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLC2</accession>
    <name>W6ZLC2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_80737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682576.1">
        <property type="nucleotide sequence ID" value="XM_007684386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLC2"/>
    <dbReference type="STRING" id="930090.W6ZLC2"/>
    <dbReference type="ESTHER" id="cocmi-w6zlc2">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="19125719"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80737"/>
    <dbReference type="eggNOG" id="KOG1516">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_14_4_1"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF5">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="1">
        <location>
            <begin position="55"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="552" mass="61720" checksum="109C8E4489C9B49E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLL4</accession>
    <name>W6ZLL4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_87364</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="5"/>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685053.1">
        <property type="nucleotide sequence ID" value="XM_007686863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLL4"/>
    <dbReference type="STRING" id="930090.W6ZLL4"/>
    <dbReference type="GeneID" id="19127046"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87364"/>
    <dbReference type="eggNOG" id="KOG1358">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015846_0_2_1"/>
    <dbReference type="OrthoDB" id="3168162at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000059">
        <property type="entry name" value="Serine palmitoyl CoA transferase subunit LcbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF2">
        <property type="entry name" value="SERINE PALMITOYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="11">
        <location>
            <begin position="123"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC48409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="508" mass="55977" checksum="C1392C71C11A27C2" modified="2014-04-16" version="1">MDLSELQNATTRFITDASAQFNRIPGSAIAVRYIKSSYRNDPVRSAVELFLFLFAVRYLLAPKYSTQKKVQLTDAEIDELVDDWTPEPLVAPTTALEELENEKRPVIVGPTGPKSKLSNGRTVTNLASYNFYNFLSNDTLKDKAIQTLRTYGVGPCGPPGFYGTQDVHMKTEADVAAHLGVPACIIYAQSFSTISSVIPSFSKRGDIIVADRALNFAARKGIQISRSTVRWFEHNNMDDLEAVLKKVVKEQAKKPLTRRFIITEGLFENIGDVVNLPKLIELKLKYKFRLILDETWSYGVLGRTGGGVTEAQNVDAAEVDMIIGSLSGPLCAAGGFCAGNEEVVEHQRISSASYTYSAALPALLSTTASETISMLQKQPDILTGLRENIKAMRGQLDPRSDWVRCSSSAENPMMLLVLKEEVIEAKKLSIEDQNQIFREVVDECLANGVLITRLKSFPLGIGLNPKDAGWQPTPALKVCVTSGLTKKETEKAGTIIRHAITKIVSRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLP5</accession>
    <name>W6ZLP5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_98013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689006.1">
        <property type="nucleotide sequence ID" value="XM_007690816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLP5"/>
    <dbReference type="GeneID" id="19129166"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98013"/>
    <dbReference type="HOGENOM" id="CLU_3050191_0_0_1"/>
    <dbReference type="OrthoDB" id="3744425at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="54" mass="6237" checksum="C63ED6079B272ADE" modified="2014-04-16" version="1">MHHPSLQPSHSMMIRHWAPTILDGYAFYGRPQKPRRTDHFSMSYTAARINLGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLV4</accession>
    <name>W6ZLV4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Micro-fibrillar-associated protein 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_31617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682344.1">
        <property type="nucleotide sequence ID" value="XM_007684154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLV4"/>
    <dbReference type="STRING" id="930090.W6ZLV4"/>
    <dbReference type="GeneID" id="19121907"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31617"/>
    <dbReference type="eggNOG" id="KOG1425">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022379_0_0_1"/>
    <dbReference type="OrthoDB" id="1111734at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033194">
        <property type="entry name" value="MFAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009730">
        <property type="entry name" value="MFAP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15327">
        <property type="entry name" value="MICROFIBRIL-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06991">
        <property type="entry name" value="MFAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Micro-fibrillar-associated protein 1 C-terminal" evidence="2">
        <location>
            <begin position="123"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="412" mass="46644" checksum="D4152D2D142CDC0E" modified="2014-04-16" version="1">MPPPKPKKLTAQPVRTRQFAGKPAVAEPEERSSSESDSEDEEQKPQLKPFAKPKPAPIASSAAKSRLASRQKSEDARKALEDEFETESEGEGEKDGSGSGSGSGSDSGSGSDEDESSEEESGSEDEAPKKLLRPVFLKKSERNKITAPVKSADELAAEEEARRQEQARALVQEQVEQRIAEKAAGKKDWDDDIEDADINAIDDTDGVDPDAEYAAWKLRELKRIKRERLAIEEAEAERAEIERRRNLSAAEREAEDREFIEKQKEEKGDRGQMQYMQKYFHKGAFFTDELKELGVDRRNLMNARFEDDTNREILPEYMQIRDMTKLGKKGRTRYRDMKTEDTGKWGDFGDDRPRKDKGEYGVDERFRPDGHGARDRDRDGATGANAKPLGERKRFGESNDRDSKRPKIQDQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM31</accession>
    <name>W6ZM31_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_31680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51125.1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="22"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="198" mass="21899" checksum="7226DE73FAF64FA3" modified="2014-04-16" version="1">MTWQRELSSWMSPPRLKAADTPAVGQKAPPLPTFGESVQNGKPTIISFLRHCGCPFAEKTFLDLRAIAPTHLDVHFVAVSHSDRESTDKWLASLPDPSQNKQPNLHVIVDAERETYAAWGLGTSGVWHVLASMPSVLKLANKEGIKVRPTESGSRWQTAGNFAIDGESIVRWSRKNERADDMPDFKEGLDALLQDGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP50</accession>
    <name>W6ZP50_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">DUF7137 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_33344</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684189.1">
        <property type="nucleotide sequence ID" value="XM_007685999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZP50"/>
    <dbReference type="GeneID" id="19122298"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33344"/>
    <dbReference type="eggNOG" id="ENOG502S1TN">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058864_0_0_1"/>
    <dbReference type="OrthoDB" id="2435509at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055561">
        <property type="entry name" value="DUF7137"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42028">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42028:SF1">
        <property type="entry name" value="YALI0E30657P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23585">
        <property type="entry name" value="DUF7137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887231" description="DUF7137 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7137" evidence="3">
        <location>
            <begin position="139"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC49289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="309" mass="33226" checksum="FEACE6D83C1317C3" modified="2014-04-16" version="1">MRPARILAAVVAMSSVTHAISDAFDNIHGLADVKEVLFGRQDNNNNNNNNNNDNSKTDAPASTPAPKPTGDSNNNDNNNNSSNNNNDNKTSNNNDNKSGDNNDSKTASDPKETGTPTGKESGSKTTKKPTKSTTFDPRLPAGGITMVTPDALAGSQFYKVGDYITFAWNYTSLSVTPTAIDVLASCTANQATYTIAVNMSSAETQVVWNTKETPEGQAPFLTENYKLLIYDSNSTATAPPRAGYLGAFSGFTFGMYLPQPYTSLKDGWNCPNCNSALSNLERMTLTTMLFTCGTTVGSLVYFTYQFGLW</sequence>
</entry>
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    <accession>W6ZQW1</accession>
    <name>W6ZQW1_COCMI</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_22447</name>
    </gene>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
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    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_22447"/>
    <dbReference type="HOGENOM" id="CLU_1001112_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="278" mass="30481" checksum="FDABCF10A8077E76" modified="2014-04-16" version="1">MCKETVKDVGGVGRPVSGCGWPTVRGKNSMYYLTPRLGMGTMDVQHDSDDGEGDAQFAQSHHGRIQRVMWMWATMQVCVMCWEQLQATNMYGKGEFGGWRRSPTSSHDGADDADGADDASAGSELRRSRGPRSRHFGETEISGKMSIGVRMACQQRRACVQLINGKWASCRVSRSSVIMVIMVTGLSRSLLALACLLTSFEPAGTPGQTGRHARWVHRRSRERQAVRACLLTQKLHSDAGMRLPQASSPGTEKSLLVPLPMKSCKAPKRQPSQGISLM</sequence>
</entry>
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    <accession>W6ZRZ2</accession>
    <name>W6ZRZ2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRZ2"/>
    <dbReference type="GeneID" id="19120196"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22148"/>
    <dbReference type="HOGENOM" id="CLU_2145418_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="112" mass="12435" checksum="83735679EF0031B1" modified="2014-04-16" version="1">MYPQRPSHGPMFQLPLLGYLHLTWPVPRTHKRAIISERKPGNVHDEASGCRPPNGCMEWLRGTAARGQGNARVHAQSSGPVGWKEEKKKVRQNWQKQSRGTEGGEGRGEGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZS93</accession>
    <name>W6ZS93_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_4347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686873.1">
        <property type="nucleotide sequence ID" value="XM_007688683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZS93"/>
    <dbReference type="STRING" id="930090.W6ZS93"/>
    <dbReference type="GeneID" id="19124210"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4347"/>
    <dbReference type="eggNOG" id="KOG1408">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005113_0_0_1"/>
    <dbReference type="OrthoDB" id="6252103at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
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    <sequence length="1069" mass="115831" checksum="51AC71969F052579" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6ZSQ6</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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            <begin position="1"/>
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            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="85" mass="9307" checksum="5D86706A7E8E578B" modified="2014-04-16" version="1">MLYNPYPCLSSPSPTTMSTPLATPTLLTAEEAAFEMEKAAITSYEQGWDGWDGPVWPVGYVQCSMQMDGYVRPRVAVEGVDDVEA</sequence>
</entry>
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            <taxon>Dothideomycetes</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
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        <reaction evidence="10">
            <text>gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
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        </reaction>
    </comment>
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            <name>Mg(2+)</name>
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        </cofactor>
        <text evidence="10 12">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-grasp fold, B domain"/>
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    </dbReference>
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        <property type="entry name" value="Glutathione synthase, substrate-binding domain superfamily, eukaryotic"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
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        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
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        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
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        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01986">
        <property type="entry name" value="glut_syn_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130:SF0">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 10 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione synthase substrate-binding" evidence="14">
        <location>
            <begin position="227"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="160"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="236"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="297"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="431"/>
            <end position="434"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
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        <location>
            <position position="489"/>
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        <ligand>
            <name>substrate</name>
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        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <feature type="binding site" evidence="11">
        <location>
            <position position="497"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <feature type="binding site" evidence="13">
        <location>
            <begin position="500"/>
            <end position="501"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        </source>
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        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49026.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="515" mass="56841" checksum="6809B398529B3E7F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W7A047</accession>
    <name>W7A047_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Succinate dehydrogenase assembly factor 2, mitochondrial</fullName>
            <shortName evidence="4">SDH assembly factor 2</shortName>
            <shortName evidence="4">SDHAF2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_84785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="4">Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with the flavoprotein subunit within the SDH catalytic dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SDHAF2 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC49376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="19126531"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="SDH_sf"/>
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    <dbReference type="InterPro" id="IPR028882">
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    </dbReference>
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        <property type="entry name" value="PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="YgfY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="253"/>
        </location>
    </feature>
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        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
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        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="313" mass="34499" checksum="9E9381A866184012" modified="2014-04-16" version="1">MVSSRIITLSSRALLSLQRTQCRTFSIAPLRNGEFDALNKRTNDTSETYRKYQIEKPLNPHLTNSTSTIANKMPSVGKDSAPPELITQVDDKFAPKDSSPENTERMTGGTQNSKAQDVSGTNSELGVGEMEGAKFKVEPLKRTGEDANTMHQSRKRGTLESDLLLSTFADAHLATMSPSLMQQYDTFLDENDWDIYYWATQEPTPTSHETAEGGGSALSTSNAQGLDAATQTKLPEKDERKRDPGEGEWAQTVGTFKPAYRPVPTRWKGSEILSLLRKHVNERKAGGVIEGEGQKQQEGKGLGMMPAVKNFDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1P7</accession>
    <name>W7A1P7_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit delta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_1363</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683492.1">
        <property type="nucleotide sequence ID" value="XM_007685302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A1P7"/>
    <dbReference type="STRING" id="930090.W7A1P7"/>
    <dbReference type="GeneID" id="19119846"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1363"/>
    <dbReference type="eggNOG" id="KOG1467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016218_3_0_1"/>
    <dbReference type="OrthoDB" id="10254737at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233:SF14">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="518" mass="56389" checksum="DD929D54B9B4AF35" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W7A475</accession>
    <name>W7A475_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">uS12 prolyl 3,4-dihydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_80749</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + 2-oxoglutarate + O2 = [ribosomal protein uS12]-(3S)-3,4-dihydroxy-L-proline + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:54160"/>
            <dbReference type="Rhea" id="RHEA-COMP:13817"/>
            <dbReference type="Rhea" id="RHEA-COMP:13818"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:85428"/>
            <dbReference type="ChEBI" id="CHEBI:138052"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[ribosomal protein uS12]-L-proline + 2-oxoglutarate + O2 = [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:54156"/>
            <dbReference type="Rhea" id="RHEA-COMP:13816"/>
            <dbReference type="Rhea" id="RHEA-COMP:13818"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:85428"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682575.1">
        <property type="nucleotide sequence ID" value="XM_007684385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A475"/>
    <dbReference type="STRING" id="930090.W7A475"/>
    <dbReference type="GeneID" id="19125725"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80749"/>
    <dbReference type="eggNOG" id="KOG3844">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017005_0_0_1"/>
    <dbReference type="OrthoDB" id="430522at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019826">
        <property type="term" value="F:oxygen sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140311">
        <property type="term" value="F:protein sequestering activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071456">
        <property type="term" value="P:cellular response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000639">
        <property type="term" value="P:negative regulation of SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032436">
        <property type="term" value="P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006449">
        <property type="term" value="P:regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000014">
        <property type="entry name" value="Prolyl 3,4-dihydroxylase TPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.20">
        <property type="entry name" value="Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019601">
        <property type="entry name" value="Oxoglutarate/Fe-dep_Oase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043044">
        <property type="entry name" value="TPA1/Ofd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039558">
        <property type="entry name" value="TPA1/OFD1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051842">
        <property type="entry name" value="uS12_prolyl_hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117:SF0">
        <property type="entry name" value="PROLYL 3-HYDROXYLASE OGFOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13661">
        <property type="entry name" value="2OG-FeII_Oxy_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10637">
        <property type="entry name" value="Ofd1_CTDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="14">
        <location>
            <begin position="138"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="492"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="501"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="528"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="562"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00051966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00081607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC50876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="659" mass="74547" checksum="AAD94DF28F20C942" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJI1</accession>
    <name>W6YJI1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_10387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964361">
        <property type="protein sequence ID" value="EUC39527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693955.1">
        <property type="nucleotide sequence ID" value="XM_007695765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YJI1"/>
    <dbReference type="STRING" id="930090.W6YJI1"/>
    <dbReference type="GeneID" id="19118390"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10387"/>
    <dbReference type="HOGENOM" id="CLU_2757417_0_0_1"/>
    <dbReference type="OrthoDB" id="3686619at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="70" mass="8047" checksum="E75FB89005CB50C5" modified="2014-04-16" version="1">MSRNSNEYINVPSTTLEGDINMTGTTPNKRKSISKPKMALLEKFDGSPHELWTFLTNIDLYNEYHDVLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YKW9</accession>
    <name>W6YKW9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_41720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964238">
        <property type="protein sequence ID" value="EUC39842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693636.1">
        <property type="nucleotide sequence ID" value="XM_007695446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YKW9"/>
    <dbReference type="GeneID" id="19124121"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41720"/>
    <dbReference type="eggNOG" id="ENOG502S6FA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033740_0_0_1"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF117">
        <property type="entry name" value="ZINC FINGER PROTEIN WECKLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="108"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC39842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="405" mass="45434" checksum="11C715C8FC572999" modified="2014-04-16" version="1">MTLRTSDLFECFCGRTYTYAIDLEEHRRARGHFPSHVCRGSCRHPPVAQYNFTIRKCGYCGKLCERLDIFEDHYIATGHCFCSECDLPFESQSAWKNHCEVELHASEYRCCNCDISFKDIHALNAHMARLVHRNPLQQQPHGNARKAEKVTTASAGDRTCKKCQRTFPSLQSFQQHWKGCKRKFSAPSALLHHLESGKCCSGMDRDDIYDIVQLYDKDHTIHTLPKLTPSSSTYLSAHGLSPDSGTPTASLDSSDGWLLVTPTHSQGSVEGSLVDWTPLEDSRLSLGSRHVIDGIKPELRCPLCPRKSKAFRTIQALQQHIVSPAHCDKVYHCPRNLLSINSSKAETKQGKAKQFTTLSGLAQHLESGACHGGRQTFLRCIEFIQQHLGQWGLGGMRLLLPGSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YL58</accession>
    <name>W6YL58_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964221">
        <property type="protein sequence ID" value="EUC39932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693559.1">
        <property type="nucleotide sequence ID" value="XM_007695369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YL58"/>
    <dbReference type="STRING" id="930090.W6YL58"/>
    <dbReference type="GeneID" id="19119549"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110127"/>
    <dbReference type="eggNOG" id="ENOG502SR9S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_946612_0_0_1"/>
    <dbReference type="OrthoDB" id="3679304at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="319" mass="36281" checksum="F17A1BF463CE585D" modified="2014-04-16" version="1">MPVRRSRRRTGFQNIESAWALLIDTLNDIELSQRLTKRHDQRIAKVTADEKTTRSGASLKQHKFLKRVSAINPDFYKLCVVAFSQNQISFTKNAILDGLVERIRGERDGTIISPATRSLLHRSEDDRPIPLPQETIELPKTPSEPWVELRYAEREGIEKVFGQYLLDRIENTDLRQNWRAVFMRLPMWPQDLSGPCFMSLNLCEGSVKEVAMALFKVEVTWRTNAFWIVHENGLLQIIPHSQYTMKGVSDEDIIAVFGADIHAAITTCSIRANELREGDRRTKCVSITFSEKRAVINLILSVSEGVKIQSKLSVSATSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YM43</accession>
    <name>W6YM43_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_109146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964177">
        <property type="protein sequence ID" value="EUC40307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693178.1">
        <property type="nucleotide sequence ID" value="XM_007694988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YM43"/>
    <dbReference type="GeneID" id="19119377"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109146"/>
    <dbReference type="eggNOG" id="ENOG502SBG2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099958_0_0_1"/>
    <dbReference type="OrthoDB" id="5274873at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18683" checksum="4E075706AC23CC6F" modified="2014-04-16" version="1">MFYVMYLTGLCQRRHWPDPLFQTFRTRYGYGSTVRVNNREYSTDVEYESEELAKNAAATRAYMICRNFSVNDGMYPGQRPGEGAQGLPTPIGAGRRNTTSSNDYDSSSTISGGTSPRSSDCGLDAAQAAAAGRRPSKASATPSTPSACCCGRGYVRAYERCSGCLQDAGYRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMS9</accession>
    <name>W6YMS9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_9563</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964153">
        <property type="protein sequence ID" value="EUC40587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692895.1">
        <property type="nucleotide sequence ID" value="XM_007694705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMS9"/>
    <dbReference type="GeneID" id="19128699"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9563"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_6_1"/>
    <dbReference type="OrthoDB" id="2533084at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF181">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="517"/>
        </location>
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            <end position="535"/>
        </location>
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        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="535" mass="57913" checksum="40EDE8E3CDDFAB48" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
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    </reference>
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    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="55816" checksum="0CF120F0F11FCAED" modified="2014-04-16" version="1">MDRSTKPSFNFVNLQHPDDLKNEETQLRIRRLAMTEVGKARRKPKTKRARHEIVLEFRKPSEQSRMHVDRFGGGQLDPFGPYPVELDDSERALLANVLTTEDNNHPTVLRGSWYPVGLSYIPAFWNMLANSQNFLNEKRHGYFPSQDDAVALKIHHKALRHTTEMMKDPKMHQSDELIGSMVSFMIHQALLGNFAGDVWQKHADALARIVQLRGGYDSITTDFLRVTVSWGDLIGSFFQDRSPIVPMPSQWLMDSKSPPNSPRPANAISLSWKYQLPMQLDWITIFDDIVQLISLDRMFNEKQFMLAITSGSWMEPTVYRLLSIRPLHKGNSREHVMEEVCRLGTLLFLSPFWRALGQSPVRTSAISRNLLLVLLENMIEWNELKPLLIWAIYFAAIETKDLAERSQFVLMLGILMSGMQLQEWDGLMNIVKEVLWVEKIFAGTDDLIREEVMQIVNHHRSNNARPDSVPMGILEAFAADVEEEH</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC41152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="57" mass="6132" checksum="1AFF0AA32812F451" modified="2014-04-16" version="1">MRTGYGWGWNTLCMHCAKLHPCGKGSILLGDLRRATSAGRSSEGFGFLELPCMGNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPS2</accession>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="OrthoDB" id="10500695at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886599" evidence="1">
        <location>
            <begin position="17"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="96" mass="9915" checksum="ADAA9A6B66E6C08E" modified="2014-04-16" version="1">MNFFILSATIIATVSALTVDLALSSCPNAAAFNITQTIDGDDILPLPVDAGPVCGIQVISASPNTSFSAVECALILGEDDYPIDQVASASSPYCYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPU0</accession>
    <name>W6YPU0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_111292</name>
    </gene>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964347">
        <property type="protein sequence ID" value="EUC39538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPU0"/>
    <dbReference type="STRING" id="930090.W6YPU0"/>
    <dbReference type="GeneID" id="19119746"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111292"/>
    <dbReference type="eggNOG" id="ENOG502RZB9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1717681_0_0_1"/>
    <dbReference type="OrthoDB" id="434972at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC39538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="178" mass="19628" checksum="4747F602F60E8089" modified="2014-04-16" version="1">MWIAALHCNTLVCTIAYTAAIMIYNEGGFAAFAILKNVVGAFGLMCECWGTAVTFSDGEDLHGKKALSILIFGLIFSTTGHAQDFRDRSADAVMGRKTIPLVLSQPLARWSLAVLIAAWTAGLIVFWQPPVVISITFSFLALRTLGGYLMSYEEKDDSVSYVYYGVRLFFETKTARRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPW6</accession>
    <name>W6YPW6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_106180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964103">
        <property type="protein sequence ID" value="EUC41427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692055.1">
        <property type="nucleotide sequence ID" value="XM_007693865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPW6"/>
    <dbReference type="GeneID" id="19118815"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106180"/>
    <dbReference type="HOGENOM" id="CLU_3068297_0_0_1"/>
    <dbReference type="OrthoDB" id="10294718at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="53" mass="6090" checksum="1B9031AC581BB978" modified="2014-04-16" version="1">MEALDTPVLQPLLTSHHPLTSFPKASMGVRHVLNDWTRVYFSITKVWTLPFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPW9</accession>
    <name>W6YPW9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_106211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964103">
        <property type="protein sequence ID" value="EUC41432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692056.1">
        <property type="nucleotide sequence ID" value="XM_007693866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPW9"/>
    <dbReference type="GeneID" id="19118819"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106211"/>
    <dbReference type="eggNOG" id="ENOG502RHA2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010210_2_0_1"/>
    <dbReference type="OrthoDB" id="8059989at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818:SF3">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="335"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="891"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="893"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1074" mass="120650" checksum="18D80E28ACBA07ED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ08</accession>
    <name>W6YQ08_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fumarylacetoacetase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_29767</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964101">
        <property type="protein sequence ID" value="EUC41482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692005.1">
        <property type="nucleotide sequence ID" value="XM_007693815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ08"/>
    <dbReference type="STRING" id="930090.W6YQ08"/>
    <dbReference type="GeneID" id="19121565"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29767"/>
    <dbReference type="eggNOG" id="KOG1535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_2_1_1"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF100">
        <property type="entry name" value="FUMARYLACETOACETATE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G01490)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="90"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="257" mass="28287" checksum="4EDCA8AED913AFFF" modified="2014-04-16" version="1">MLVPWNRLIRFVATDGQVLRGEPILPHPDFDLGQTDEKTKLQARVIIGNDIYDTTGKTRVPDEVVTVRKLLGPLERNDVDILRCVGLNYAKHTDYEGELVLIIGRDAKDVKLEDALDYVAAYTAGNDISSRKLQRDPKLAGGVPQWGFSKGFDTFAPLGPALVRPDLIGDYRELLLQTMIDGDTRQKESLSDLLFDCSYLIHYLSQGTTLRKGSVIMTGTPGGVGASLKPPRYLVPGTTMEVVISKIGTLKNGVEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQE1</accession>
    <name>W6YQE1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_41823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964274">
        <property type="protein sequence ID" value="EUC39703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693775.1">
        <property type="nucleotide sequence ID" value="XM_007695585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQE1"/>
    <dbReference type="STRING" id="930090.W6YQE1"/>
    <dbReference type="GeneID" id="19124136"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41823"/>
    <dbReference type="eggNOG" id="ENOG502SNVG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_681502_0_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="45395" checksum="8FFAF9ACF7D86D78" modified="2014-04-16" version="1">MPRKRSSRTAANDDDDDWHHISDQTLRKRIQNRVAQRKHQFPDEMNLWSYPPELVLNGPFPCTSGHSSDGVSDTFMSATLNDVDLNMASNTTSLSRHPAAQMVQSGDGSLLRRPDAMPWSAGSDQEVPRNSKPSNLGNLNFIEQSLVDTTTAAKGTPQSYRSNSCSDTAGSSRGIVSQKQRADYFNTPLSAIFDFHYGRNSNSSTQDSRRESSTEDRSLDSPTAQMNNKDSRKDNSSTDSLRCVATRIEKAIENIRELGFDSIDELATQYYTADLQHRPALQHRRQLSRRRGLVDLLRAIDEDSRDKWTEWEVQRYRDEVLRSAEEILDEEFSRFVKLYGNGKNTEGNLAEQRRRFQDKLPNLSSLLNVLGMSVQPQGNADRTAATVCAISVLLDSLGVSSPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQP5</accession>
    <name>W6YQP5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein uS3m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_110456</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964241">
        <property type="protein sequence ID" value="EUC39828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693655.1">
        <property type="nucleotide sequence ID" value="XM_007695465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQP5"/>
    <dbReference type="STRING" id="930090.W6YQP5"/>
    <dbReference type="GeneID" id="19119603"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110456"/>
    <dbReference type="eggNOG" id="ENOG502SRRH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080064_0_0_1"/>
    <dbReference type="OrthoDB" id="4360278at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007980">
        <property type="entry name" value="Ribosomal_uS3m_fun"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05316">
        <property type="entry name" value="VAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC39828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="303" mass="35387" checksum="3DC67F50FC94DD31" modified="2014-04-16" version="1" fragment="single">SSVYSYNKSYLKSLISKDAVLNTLLRSYCNMLQDKIKILFKRRRDNKIRYSANKIYASRAELKHTNTKLFITLYLYNKQKSSIEYFLVNLRRKYLKLSNIPTYNIRLLKKLVRLQKILFNSLKLLNFNKSKFNSLNLNLRNFGLISLIEKLYNKKVEINLVELRSIHLNSDVFSSAVALKLRDRKNKAVRVLRKAILQMVRIPDLHTLITFDDNIEAMNKNNIINTIKQQVVSGVRFEASGRLTRRLTAMRAVFKYRYAGSLKNIRSSFNNKSSTMLRGYAKSNVQYTLINSKTRNGTFGLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR70</accession>
    <name>W6YR70_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_109590</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964195">
        <property type="protein sequence ID" value="EUC40130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693358.1">
        <property type="nucleotide sequence ID" value="XM_007695168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR70"/>
    <dbReference type="GeneID" id="19119463"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109590"/>
    <dbReference type="eggNOG" id="KOG0134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_6_3_1"/>
    <dbReference type="OrthoDB" id="1663137at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04733">
        <property type="entry name" value="OYE_like_2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051799">
        <property type="entry name" value="NADH_flavin_oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656:SF5">
        <property type="entry name" value="NADH:FLAVIN OXIDOREDUCTASE_NADH OXIDASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="5">
        <location>
            <begin position="18"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="448" mass="49488" checksum="0EE4141831E4CB64" modified="2014-04-16" version="1">MAPQRYEAEHKDPAPLGKPLDFVFSKRTAQNRFLKGAMTERLSSFDPDVLENRGVPSKELVNVYRRWGKGEYGVILTGNIMIEYDHLEAAGNPIIPRDAKFEGERFEMFKEIATEGKKHGSLMVGQVSHPGRQVTEEIQKNPISASDVQLTNNLMGMTFAKPRAATEGDIKNVVNGFAHAAEYLEKAGYDGIQLHGAHGYLLAQFLSPTTNLRTDAYGGSLENRARIVTEIGQEIRKRTSSSFILGIKLNSVEFQDKGFNTEDAATLCQLLESNSFDFVELSGGTYEHLAFSHQRESTKKREAFFLDFAEKITPSLSKTKTYVTGGFKTVPAMLNALSAVDGIGLARPTCLEPELPRQILAGEVNATIKQRMEDGEFGISLVVAGAQIKQLGKDEQPIDLSDEANYAAFLKDMEEWTRQDRKHGKGYGHMDVKSVKAVPYGAPVATTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRG4</accession>
    <name>W6YRG4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_109418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964187">
        <property type="protein sequence ID" value="EUC40205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693282.1">
        <property type="nucleotide sequence ID" value="XM_007695092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRG4"/>
    <dbReference type="GeneID" id="19119427"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109418"/>
    <dbReference type="eggNOG" id="ENOG502SQ3E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011409_12_2_1"/>
    <dbReference type="OrthoDB" id="3598904at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF12">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC40205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="570" mass="63680" checksum="EAFF7ECD9A4ADEF1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRG9</accession>
    <name>W6YRG9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_104548</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964075">
        <property type="protein sequence ID" value="EUC42042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691438.1">
        <property type="nucleotide sequence ID" value="XM_007693248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRG9"/>
    <dbReference type="GeneID" id="19118532"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104548"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF57">
        <property type="entry name" value="MALTOSE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="387"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="66"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="541" mass="59990" checksum="74A513D08E1D56F8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSM2</accession>
    <name>W6YSM2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 3 subunit B</fullName>
            <shortName evidence="8">eIF3b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Eukaryotic translation initiation factor 3 90 kDa subunit homolog</fullName>
            <shortName evidence="8">eIF3 p90</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Translation initiation factor eIF3, p90 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PRT1</name>
        <name evidence="11" type="ORF">COCMIDRAFT_9628</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the eIF-3 subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964159">
        <property type="protein sequence ID" value="EUC40513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692972.1">
        <property type="nucleotide sequence ID" value="XM_007694782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSM2"/>
    <dbReference type="STRING" id="930090.W6YSM2"/>
    <dbReference type="GeneID" id="19128818"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9628"/>
    <dbReference type="eggNOG" id="KOG2314">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011152_4_0_1"/>
    <dbReference type="OrthoDB" id="10250414at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12278">
        <property type="entry name" value="RRM_eIF3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000419">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000235">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03001">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011400">
        <property type="entry name" value="EIF3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034363">
        <property type="entry name" value="eIF3B_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036424">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="40"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR036424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="741" mass="84767" checksum="661188355CF707C3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT69</accession>
    <name>W6YT69_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_107884</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964139">
        <property type="protein sequence ID" value="EUC40790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692692.1">
        <property type="nucleotide sequence ID" value="XM_007694502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT69"/>
    <dbReference type="GeneID" id="19119140"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107884"/>
    <dbReference type="eggNOG" id="ENOG502R3M8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027816_3_1_1"/>
    <dbReference type="OrthoDB" id="3162524at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000039">
        <property type="entry name" value="Neutral amino acid transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF694">
        <property type="entry name" value="AMINO ACID PERMEASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="45"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="465" mass="49894" checksum="078CB506AEA9D66B" modified="2014-04-16" version="1">MAEKNEDVIAPAPSHSSGSIGETKSDLENDNEVFKKGEGYEDFRTVGWVQTTMILLKIIFATGVLTIPSAMYTLGALPGAINVIGWQAVNTWAALVLGQFRMRHPGCHSIADMGLLVGGPIVKEITGVLFLVAFVIVAASGIVGVSTALNALSNHSLCTNYFSLIATLMVGLCASVRKFEKIAWITWAGFVSVFIAVFIVVVGVTTRDRPAAAPQTGPYDFGYHVIGHPTFAAGITASSTIFCSSAATSAFLPVMSEMRNPRHFGRSVMTCMTFVGAAYLSFSLVVYKWCGKWVASPSLGSAGPTIKKVAYGIGIIGLLVSGALYVHIGAKYIFVRILRKSRHLQSNTFVHWGTWFGCVGGMTIVSFLIASGVPIFNYLLSLAGSLAFAPLGIGYPGWLWIYDHRDHWRGSFPQKMMYLLHVAFIGLSAFLTVGGTYGVIVQIKDAYKDGSIDSAFSCADNSNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTG1</accession>
    <name>W6YTG1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_40861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964133">
        <property type="protein sequence ID" value="EUC40885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692601.1">
        <property type="nucleotide sequence ID" value="XM_007694411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTG1"/>
    <dbReference type="GeneID" id="19123956"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40861"/>
    <dbReference type="HOGENOM" id="CLU_781120_0_0_1"/>
    <dbReference type="OrthoDB" id="3670965at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="377" mass="42261" checksum="68523B0F12A46F6C" modified="2014-04-16" version="1">MAPASADASPSDSLEDQPRENGLVIQPTSKRSYRCKSCGISFPCHEPWQHHANKHGETFPHIHIELKPLALAPDVIALHDVYCRRRTHYVRVTSSTPLGPFSAIQRIDEVEELTFKEFLKRDFTSTENHKAIVRRMEEFDKKCCKSVHERTTFVTKKLVNRLLSCFPCISVPEQSRPSRWPSRPDMRSKSPSQSTKALAANDGLSQHTEDLTLTVSRPSRLHTSLKSPSQSTEAITVNDRRSQDVDDPASTARNSLPQNVAAVVAVASFYSTAKGVHGHEVLVTTHSDTIILLQRVDLDALLQYTRTKKQLQEIVGEYAYTGLLEYRKKGIDIEEPVYQGFLPDDLPIGVGEEVRLEDCSPVLEAEVRSALDSHVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTG6</accession>
    <name>W6YTG6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable enoyl-CoA hydratase, mitochondrial</fullName>
            <ecNumber evidence="3">4.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_39218</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="3"/>
    <dbReference type="EMBL" id="KI964050">
        <property type="protein sequence ID" value="EUC42747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690721.1">
        <property type="nucleotide sequence ID" value="XM_007692531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTG6"/>
    <dbReference type="STRING" id="930090.W6YTG6"/>
    <dbReference type="GeneID" id="19123639"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39218"/>
    <dbReference type="eggNOG" id="KOG1680">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000019">
        <property type="entry name" value="Enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00073937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="289" mass="30959" checksum="BEFB9FD260082C7E" modified="2014-04-16" version="1">MQAFRSAPRVASQFRSTGLPRFVRGFTTDKSYEHLLVSVPKEGVGLIQLNRPKALNALCTPLILELNQALRDFQNAKSIGAIVLTGSEKAFAAGADIKEMKDLTFSDAYGNDFIESWSDLVTFLKKPLITAVNGHALGGGCELAMMGDIMYAGPKANFGQPEIKLGVIPGAGGSQRLTKAIGKSRAMEVILTGDNVTAQQASEWGLVAKVFETPEACVDGAIATAAKIASYSQIAVKAAKEVVNKSQDLGIREGVEYERRVFHGLFGSQDQKIGMAAFAAKEKATWTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTM4</accession>
    <name>W6YTM4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964049">
        <property type="protein sequence ID" value="EUC42797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690694.1">
        <property type="nucleotide sequence ID" value="XM_007692504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTM4"/>
    <dbReference type="STRING" id="930090.W6YTM4"/>
    <dbReference type="GeneID" id="19123635"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39208"/>
    <dbReference type="eggNOG" id="ENOG502SSJ0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000907_3_0_1"/>
    <dbReference type="OrthoDB" id="67027at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="1">
        <location>
            <begin position="93"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="239" mass="26667" checksum="0C11B9AB0C0FF988" modified="2014-04-16" version="1">MRYSSWLPLARYAAPKVAAIPLKSRSSFPRAHFQTTLQRKYDTPTINIDRKIAGVEKVFDYYFKNKMICAESVQMAAPEVLLRIKGREYSIVHNRRLELVGDKIMGLVLSQKWYQVRNQNGQTTPVKTWNDIHKSLVSNEALAARGFKLGLDAFVVPASGVHVTKNMMADAFEAMVGAVSLDAGEDAIEAVHGVLERTGFFNHPMLVRWIGVSNCDNDDPFASVTSHCVAIVDDSHVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUH1</accession>
    <name>W6YUH1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_106841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964116">
        <property type="protein sequence ID" value="EUC41175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692315.1">
        <property type="nucleotide sequence ID" value="XM_007694125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUH1"/>
    <dbReference type="STRING" id="930090.W6YUH1"/>
    <dbReference type="GeneID" id="19118931"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106841"/>
    <dbReference type="eggNOG" id="ENOG502S4UX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050730_0_0_1"/>
    <dbReference type="OrthoDB" id="2532955at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03440">
        <property type="entry name" value="hot_dog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052389">
        <property type="entry name" value="Sec_Metab_Biosynth-Assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38110">
        <property type="entry name" value="CHROMOSOME 23, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38110:SF1">
        <property type="entry name" value="THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="1">
        <location>
            <begin position="23"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="2">
        <location>
            <begin position="169"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="33155" checksum="3B3B4CC5DE417852" modified="2014-04-16" version="1">MPGWREATTVQKLSTNTYSCTLHDDWCIGTVPNGGYVTGCLLEVVKAHFSSTLSAQNQPHTIALHVEFLRRTQAGPATFTVDDVKLGRQTSIVHVSMQQDGRQEIVAYVTNSNMDTESGFSYDTEYQLSPPVASVDISKLEKGEDPLWERHAELPYASFRKATSKVLFHFPRQGHPAANTADEWICFADGSTFNDSSIGFVADMFPQLVERFKEKGTGPFWYPTLLLNLDFKKSLPAEGVKWLRVRVEMKKVFNGRMDIEVFVHDAEGELVALSHHVGLVVDASRNTAARRVGDAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW11</accession>
    <name>W6YW11_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964089">
        <property type="protein sequence ID" value="EUC41720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW11"/>
    <dbReference type="GeneID" id="19123819"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40131"/>
    <dbReference type="eggNOG" id="KOG1197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_2_1"/>
    <dbReference type="OrthoDB" id="203908at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08273">
        <property type="entry name" value="MDR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="14"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="338" mass="36334" checksum="C463F32799F582A2" modified="2014-04-16" version="1">MALPIRKVLIPTHGDPSVVTLTTTTLPAPSPTQVQIKILYSSMGGGDILMRQGIYPLQQKAPLTPGYTLIGRVSQNGSRARKFAHGALVACLCVYDGQATYSNQPEKYLVPVPEGVDLQQAVALVLDWSTAYGLAYRAAEIGPGKKVFIHGLSGSVGFALLTFCKRQGASVYGTAAAHNHAVVREAGATPFVYTDKEWMGVMKAMGGAHVVYDALGFASWDESWSILSSDGGHLVGYGGNLNSLNGDKPRGNTLQIAKLLAKGKVPFCPYRTSFFYIDRDQKTYRPELEALFEMLAKGEIKVPVRKVWGLEEVPEAHRVWAKGPGVGAVVVKVAEDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWQ6</accession>
    <name>W6YWQ6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Short-chain dehydrogenase/reductase 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Retinal short-chain dehydrogenase/reductase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_99803</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689648.1">
        <property type="nucleotide sequence ID" value="XM_007691458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWQ6"/>
    <dbReference type="GeneID" id="19129539"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99803"/>
    <dbReference type="eggNOG" id="KOG1201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_5_1_1"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052650">
        <property type="term" value="F:all-trans-retinol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05339">
        <property type="entry name" value="17beta-HSDXI-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000131">
        <property type="entry name" value="Short-chain dehydrogenase/reductase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase" evidence="14">
        <location>
            <begin position="113"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00059620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC43817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="379" mass="41656" checksum="C7F6FBB872ED5A0E" modified="2014-04-16" version="1">MRQQASCIDMPAMPSGIKEIPVQLPKSFDRPDEPWHHYLTIDLIWYVFGYTIFHPFVSWVVVLCLRAQYTPYGNLEMRLATAWAMLMSIIGLFGLLSDRIAFGPPREVDLAEEVIVVTGGAEGLGALLAETYGMRNANIAVLDTKKVDDEVSENTGVLYYECDVSDAKQVEAAAVQIIEDLGAPTILINNAGIMQPKSVLDSTAEEVERTFRVNTLAHFNTLRTFVPHMLKEGRGTIVTVASVLGHLGAANLSAYTASKAALLALHQSLRAELAQNPDAKHIKTILVTPGQMGTQMFAGLKTPSNFLAPIVTPAEIGKDIIRMIEKGDSGEIAVPLYSRYIQILGVLPFGVQHLIRKLSGMDKAVGRMREVRQELKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ59</accession>
    <name>W6YZ59_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase MRP protein 1 RNA binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_39099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964046">
        <property type="protein sequence ID" value="EUC42868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690597.1">
        <property type="nucleotide sequence ID" value="XM_007692407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ59"/>
    <dbReference type="STRING" id="930090.W6YZ59"/>
    <dbReference type="GeneID" id="19123614"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39099"/>
    <dbReference type="eggNOG" id="ENOG502S2QW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1348808_0_0_1"/>
    <dbReference type="OrthoDB" id="5414547at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000294">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, RNase MRP-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22573">
        <property type="entry name" value="RMP1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37792:SF1">
        <property type="entry name" value="RIBONUCLEASE MRP PROTEIN SUBUNIT RMP1"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="54"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="201" mass="22483" checksum="B2BAD7C32E9E14D1" modified="2014-04-16" version="1">MAIAKPSTALPHRQQSHHLTVPTTTSSSTPSISASPLFSASTHEIAMLHDIHSLLDKLFIRNRNQHRRSTWWKALHGFRKQMALLLGELEAKELREYERRQRVQARLRFWDERGEVHAWYYQFSQLVAVGPFSPLGLVMMASVARVCRITGITSVYEQIASAEVKGVLDASDELELAGKFGGVLGGGDECDEGVVIARDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ87</accession>
    <name>W6YZ87_COCMI</name>
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        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_28532</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin AB subfamily.</text>
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        <property type="protein sequence ID" value="EUC42903.1"/>
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        <property type="nucleotide sequence ID" value="XM_007692366.1"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20512">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000005">
        <property type="entry name" value="G2/mitotic-specific cyclin B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
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        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
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        <property type="entry name" value="Cyclin-like_sf"/>
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        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
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    </dbReference>
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    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0195">Cyclin</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="283"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="8">
        <location>
            <begin position="376"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="380"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="81"/>
            <end position="215"/>
        </location>
    </feature>
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        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
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            <end position="170"/>
        </location>
    </feature>
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        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006955"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="517" mass="57772" checksum="AB0BEB3D3091AD00" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZM2</accession>
    <name>W6YZM2_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">Glycosyltransferase family 15 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_5912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690471.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6YZM2"/>
    <dbReference type="GeneID" id="19124776"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5912"/>
    <dbReference type="eggNOG" id="ENOG502SMKU">
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    </dbReference>
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    <dbReference type="OrthoDB" id="3353407at2759"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205:SF2">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11885">
        <property type="entry name" value="DUF3405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889557" description="Glycosyltransferase family 15 protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="810" mass="95096" checksum="B47E6163EFB99BEE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZR7</accession>
    <name>W6YZR7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_97158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963996">
        <property type="protein sequence ID" value="EUC44832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688642.1">
        <property type="nucleotide sequence ID" value="XM_007690452.1"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="539" mass="60834" checksum="91E78700DB73BB53" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0E3</accession>
    <name>W6Z0E3_COCMI</name>
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        <recommendedName>
            <fullName evidence="8">Protein CFT1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cleavage factor two protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Protein cft1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_26607</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CFT1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC45197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_26607"/>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="mRNA cleavage and polyadenylation factor subunit"/>
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    </dbReference>
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        <property type="entry name" value="mRNA cleavage and polyadenylation factor subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
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        <location>
            <begin position="75"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="13">
        <location>
            <begin position="555"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="11">
        <location>
            <begin position="993"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1244"/>
            <end position="1270"/>
        </location>
    </feature>
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        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="457"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00038304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039443"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00041264"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC45197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1389" mass="151098" checksum="616FC5865F82A48E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0F9</accession>
    <name>W6Z0F9_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_96117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688259.1">
        <property type="nucleotide sequence ID" value="XM_007690069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0F9"/>
    <dbReference type="STRING" id="930090.W6Z0F9"/>
    <dbReference type="GeneID" id="19128790"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96117"/>
    <dbReference type="eggNOG" id="ENOG502SVIC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029545_1_0_1"/>
    <dbReference type="OrthoDB" id="128867at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052254">
        <property type="entry name" value="CUL4-DDB1_E3_ligase_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472:SF1">
        <property type="entry name" value="DDB1 AND CUL4 ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472">
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    </dbReference>
    <dbReference type="SMART" id="SM00320">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="493" mass="55101" checksum="FCD7FE6591AEB2CE" modified="2014-04-16" version="1">MNGQPIPGFYWDPEKKKYFKIQSQNAARGLDLRYSAENIRKEERKEKIQKAAVARSNKIGKERVVRRNPNSIIQTSIERELGSKRWSYYFNNLWTDVCAFGINTRPKQVISRRLCHASIRVFDRDPVSRTIYAVQGSNSVNMQRIRTKDDPPAMETDPSDHQDPLLANPYAFHPWDEVTRTTSTASSLTYLPATGALAVTTYGSDRPPEVWLSDPERDQPYVGQKFTPRDCTTIWSASARPTSFTAPPNIPTTIAASQTEHLAVAASSSLLLFTRSQCGTWDSTLALKPLSSDILALDWLSYTTLALGSRDGSIRLYDTRSGGSSHILSHPYPISKLKRADDASRLVCSGLEDSLCLYDLRSPRQLPKSSNQHYQNFPKRRKYTHGHRKAVSTPLLTFEHANREELDLDIAVHSRLGLLAAAQDLATGTAIRVSNLYTGKMVREIKCEGKGTKKGKGGWESIRSLKFVEGGGEEGGGVELWSCWNGGIGEFSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0J9</accession>
    <name>W6Z0J9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_95891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
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        <location>
            <begin position="20"/>
            <end position="351"/>
        </location>
    </feature>
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        <location>
            <begin position="29"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="213"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="351" mass="37017" checksum="717F686D03DB1753" modified="2014-04-16" version="1">MMLFKWICPVALLAVPASSSIVERATVDTLPLLTAISKDPELSIFYSLFNSTGGTSGIPGPPFEERFNVLADGRKYTAFAPVNSAFEALQPGLAAALTAPASYVLLEAILRTHIAEGLVTTKEVRSSEKPVISIEGIPLKFASEGNTVTINNQAKLVSAQGTAVGNGAIFKITSIIDPLVSIFGTDVTKNGSDIASARRRQAKKILEYELRPSGTIASALSSLPDISTYVDLLNATSPAFFSLLNSSLPAGKYISIFAPSNAALEAVGQGAKAIQPSNQPFTSYLLEYPFIDTTLVGSEKSIVGFPAVVRRDGNGAVTSVNNAAVKGEPKCVGNACVYVIDRWLDPVFGLL</sequence>
</entry>
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    <accession>W6Z1I5</accession>
    <name>W6Z1I5_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">DUF1993 domain-containing protein</fullName>
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    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_95161</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963981">
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    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1I5"/>
    <dbReference type="GeneID" id="19128599"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95161"/>
    <dbReference type="eggNOG" id="ENOG502SRAW">
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    <dbReference type="HOGENOM" id="CLU_090929_1_0_1"/>
    <dbReference type="OrthoDB" id="3724345at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR018531">
        <property type="entry name" value="DUF1993"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922">
        <property type="entry name" value="BLL2446 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922:SF1">
        <property type="entry name" value="DUF1993 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09351">
        <property type="entry name" value="DUF1993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="DinB/YfiT-like putative metalloenzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="21087" checksum="0D9E272257178998" modified="2014-04-16" version="1">MSSLTFHTMAILPAISALKNTLAFIKKGHEHALTNKIDPETFLTASLHPDMKDFRFQIYRLTDAVKFMPSRINPALETITLPDDEKTFEELEARIEKTIKYLEKFQPADFEGKEADELVVKFPSGLQISLPAVEYVYKFAHPNMWFHMTTAYGILRMKGVDIGKFDFVNGAKEIVVERWEEQK</sequence>
</entry>
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    <accession>W6Z1K9</accession>
    <name>W6Z1K9_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_99779</name>
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    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007691469.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19129531"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99779"/>
    <dbReference type="eggNOG" id="ENOG502SJHR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF7923"/>
    </dbReference>
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        <property type="entry name" value="Znf-CCCH_tandem"/>
    </dbReference>
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        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543:SF1">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25540">
        <property type="entry name" value="DUF7923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25542">
        <property type="entry name" value="zf-CCCH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25543">
        <property type="entry name" value="zf-CCCH_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="293"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="626" mass="69664" checksum="FBAADEAA58B8B98E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1V6</accession>
    <name>W6Z1V6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_100255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964022">
        <property type="protein sequence ID" value="EUC43678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691626.1"/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="LaButti K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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        </location>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <source>
            <dbReference type="EMBL" id="EUC45872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="136" mass="15010" checksum="AAC8ECD7E50D7C4A" modified="2014-04-16" version="1">MDQCKMPSFVDLKFKARMASYPSRPSPDSNATGAARLVRCSTWVRENGMQVHVHTARTKTEEPIKRGMMLIDRCRQTATEASIITGMPRHAPLYYLHGYCTVSTLALCVLISGQNRAASPLSVYIGAACRSEEATD</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat-containing domain"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="361"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="3">
        <location>
            <begin position="628"/>
            <end position="709"/>
        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="841"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC43918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="944" mass="106145" checksum="C6F3FE5B7F55CF8D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2T3</accession>
    <name>W6Z2T3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein RO7</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_99293</name>
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    <organism evidence="3 4">
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964013">
        <property type="protein sequence ID" value="EUC44033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689453.1">
        <property type="nucleotide sequence ID" value="XM_007691263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2T3"/>
    <dbReference type="STRING" id="930090.W6Z2T3"/>
    <dbReference type="GeneID" id="19129440"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99293"/>
    <dbReference type="eggNOG" id="KOG0676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023246_0_0_1"/>
    <dbReference type="OrthoDB" id="337660at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10207">
        <property type="entry name" value="ASKHA_NBD_Arp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="565" mass="62868" checksum="6D8B5726BC1A4FDC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z367</accession>
    <name>W6Z367_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="9">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_98363</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689097.1">
        <property type="nucleotide sequence ID" value="XM_007690907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z367"/>
    <dbReference type="GeneID" id="19129243"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98363"/>
    <dbReference type="eggNOG" id="ENOG502QTDU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027551_1_1_1"/>
    <dbReference type="OrthoDB" id="2425929at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF3">
        <property type="entry name" value="FERULOYL ESTERASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 9" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5029033444" description="Carboxylic ester hydrolase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC44390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="292" mass="31097" checksum="79067919DD61AE8B" modified="2014-04-16" version="1">MHSTTALISTIAAICATANGALTRVNNWGANPTNLEMNINVPAKLATKPAIILALHFCGGSGETYASTTKYNTLSEQKGFITIFPSTKKDNNCWEVNTAKGLSRDAGGDNQGLNNMIQYVIKTYSADPAKVFVTGASSGCMMTNVMMATYPDVISAATCYSGVAAGCVAGSPGASPSTADPRCANGQIIKTQAEWDAQVRAMYPSYTGQYPRFMTYHGTADSLVKYPNLGEQLKEWSGLLGVSFTRNVTNTPRSGYTSMIYGDGTKLVGVSAQNVGHWVTPDEDADMKWFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z387</accession>
    <name>W6Z387_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_39780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964072">
        <property type="protein sequence ID" value="EUC42124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691355.1">
        <property type="nucleotide sequence ID" value="XM_007693165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z387"/>
    <dbReference type="GeneID" id="19123752"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39780"/>
    <dbReference type="eggNOG" id="ENOG502SNIG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_7_0_1"/>
    <dbReference type="OrthoDB" id="9984533at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF10">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="67"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC42124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="323" mass="35212" checksum="B0DC84A0EE4BB9AF" modified="2014-04-16" version="1">MAIENILILGNGDLCRSIISALCSRQTLLSDDCNYKITVLTYLSQTLTLPINLSQFHVSHKTSDFTPTTLQSAFAGYDVILSTMAGGDSVLQISIINAVVAAGVKRFVPDEFSHDSLNKQLQARLPKHAERAKVINHLKNLSDTSPSFEWTAVATGYTLDTKIVNGDMGLDMEWQSATFHGTGMELFAVSSLARVGQVVARVLAQWEQTKNQYIYAAGAIISANDVLKSVEETTGQEFAVGNYGVEECIEEARKRVERGYPDSGLALLERSILYDGQLDASAPFRTHNANDMLGLAPELANFIVIEAYHHLKHLGKPGCACAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3Q1</accession>
    <name>W6Z3Q1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GPI inositol-deacylase winged helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_98284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="136"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="306"/>
        </location>
    </feature>
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        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44368.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="306" mass="34860" checksum="9F3B4E438AEBE356" modified="2014-04-16" version="1" fragment="single">MTWITDLVNLETGNAHLAVTSRDEQEIRTSFRHMVARNGSIAVEGEGLDGDIAAFVKDEVARLERWKNLPTIQMEIENKLVAKANGMFRYVACQIRELEDCLEPDALREALQNLPKDLNEIYSRILSRMPNGYQEKTIRLLQFLIYSPNSLSIEELVDAVAVKVDKQPAFESANRMPEPIELAKYCSSLIKLIISDSESITKAKVRLAHFTVQEYLVKYSNHSSKFTETAARADMAIVCMSYLRDIDYDSPVSQLTISFPFMTYSSKNWMSHAAASEHEKDVLGKTTDFMRDCSDLCHEYWTSIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3T2</accession>
    <name>W6Z3T2_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_4447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3T2"/>
    <dbReference type="STRING" id="930090.W6Z3T2"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_4447"/>
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    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889506" evidence="2">
        <location>
            <begin position="18"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
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            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
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            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
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            <begin position="174"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="317" mass="28989" checksum="844FF7513F1A66C4" modified="2014-04-16" version="1">MKYSIIFAIGSAALAVAAPVTVDINSRDTTVVTGGTGIGFEGQGRGGSVANGGNGGNSRKGNGGDGGAGGIAKRDTTVVTGGTGIGFEGIGRGGSVANGGDGGNTRKGNGGNGGAGGIAKRDTTVVTGGTGIGFEGRGRGGSVANGGNGGNSRKGNGGDGGAGGIGRRSTIVTGGTGIGFEGSGRGGSVANGGNGGNSRKGNGGDGGAGGIGRRSTIVTGGTGIGFEGSGRGGSVANGGNGGNSRKGDGGSGGAGGIAKRSDSIFSLIARKFTIISGGPAISFGGNAHGGDVGDAGNGGNGGRRGGSGGSSIINTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3Z6</accession>
    <name>W6Z3Z6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_103758</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC42349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692944.1"/>
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    <dbReference type="GeneID" id="19118372"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103758"/>
    <dbReference type="eggNOG" id="KOG2001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007738_0_1_1"/>
    <dbReference type="OrthoDB" id="2192946at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="209"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="545"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="36"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="771"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="861"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
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            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
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            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
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            <end position="783"/>
        </location>
    </feature>
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        <location>
            <begin position="867"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="965" mass="108670" checksum="58E32BA88A628DAE" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z475</accession>
    <name>W6Z475_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable alpha/beta-glucosidase agdC</fullName>
            <ecNumber evidence="5">3.2.1.20</ecNumber>
            <ecNumber evidence="6">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">COCMIDRAFT_5956</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="5"/>
    <dbReference type="EC" id="3.2.1.21" evidence="6"/>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688711.1">
        <property type="nucleotide sequence ID" value="XM_007690521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z475"/>
    <dbReference type="STRING" id="930090.W6Z475"/>
    <dbReference type="GeneID" id="19124792"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5956"/>
    <dbReference type="eggNOG" id="KOG1065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_11_0_1"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030459">
        <property type="entry name" value="Glyco_hydro_31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF67">
        <property type="entry name" value="ALPHA_BETA-GLUCOSIDASE AGDC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00707">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13 17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="10 17 23" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 19" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886443" description="Probable alpha/beta-glucosidase agdC" evidence="19">
        <location>
            <begin position="18"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="21">
        <location>
            <begin position="109"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="20">
        <location>
            <begin position="270"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="22">
        <location>
            <begin position="702"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="448"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EUC44715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="927" mass="103043" checksum="FFAB87852ECE8DAD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4V2</accession>
    <name>W6Z4V2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_4194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686684.1">
        <property type="nucleotide sequence ID" value="XM_007688494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4V2"/>
    <dbReference type="GeneID" id="19124159"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4194"/>
    <dbReference type="HOGENOM" id="CLU_645550_0_0_1"/>
    <dbReference type="OrthoDB" id="3688622at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="418" mass="45932" checksum="A47F93E6C26838A1" modified="2014-04-16" version="1">MSADLPSFWFPPPGPALPPLPESTLELKPPEDDPRLNGTIEYVEYLHWYMYNILQNEENYLNGNFSWNESNIHMGDVIVPVSKAPERNIYGTEYDWVRGWEMWCFRCPSTVAPEEPERDPITGYPFCGESILSMEPLRFFSTMKKEPELEVPVSTVPGADSVMACVIEQQVNPEWFRVSSTAPQLGPIITKPFIVSRSLRDSDSGARYRYDEAFPWGVLDDAQATPSPSSYPSYPTSTPTSTTDFWDWYDSYTPTSVSNPSVNPAAFTSNSKDNAPSAGLIIGVLVPVALIIGIIACFGKRARAKQQKTTAASAPPVNMNPTADAHRQAAFAAPATATVQGDGDDMPPPAYHKVISNVERMDIERRMHAEGTTPAGWPPTYTDTQHAESTVVSPPDPVASVPGTSRAPYPALPSSPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4X5</accession>
    <name>W6Z4X5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">High-temperature-induced dauer-formation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_97333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688696.1">
        <property type="nucleotide sequence ID" value="XM_007690506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4X5"/>
    <dbReference type="STRING" id="930090.W6Z4X5"/>
    <dbReference type="GeneID" id="19129035"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97333"/>
    <dbReference type="eggNOG" id="KOG2226">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007392_0_0_1"/>
    <dbReference type="OrthoDB" id="432953at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000138">
        <property type="term" value="C:Golgi trans cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026705">
        <property type="entry name" value="Hid-1/Ecm30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575:SF12">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12722">
        <property type="entry name" value="Hid1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="863"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="653"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="883" mass="98288" checksum="8D32DE61A21C619F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5I5</accession>
    <name>W6Z5I5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688236.1">
        <property type="nucleotide sequence ID" value="XM_007690046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5I5"/>
    <dbReference type="GeneID" id="19123161"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37004"/>
    <dbReference type="eggNOG" id="ENOG502QTM1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030671_1_0_1"/>
    <dbReference type="OrthoDB" id="5396at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF10">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="40417" checksum="B1B2888B4018220B" modified="2014-04-16" version="1">MDPKNTANRRLTQIKDSLTMEKTATSIPWDPNSTKFPTRKQLPGIPGAPKGAAWVWGDNDYIGRLNLLTPTRVAAAAKEIKSGEIVPVNLPLNVPNVPSFSREPFKHEVKTVIEGIVYDDMYHLNTQSGTQWDGFRHFAHIASGNFYNGTKGSDIAGPSANHKCSIHHWANHGIAGRGVLLDYRSYANKKGIAYDPYEYHPISFDELYQCGKDQGIDIRPVAQGGDIKPGDMLFVRSGWKEAYDGKSDEERAKAAVPHDAGKGGADGHRFAGVSQEEKILDWLHDCYFAAVAGDSPTFEAWPTHEEYYLHEHILALWGMPLGEMLDLEKLAQTCREKGRWFFFFSSAPANCPGGVSSHVNGTAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5M8</accession>
    <name>W6Z5M8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alcohol dehydrogenase-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_96004</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688200.1">
        <property type="nucleotide sequence ID" value="XM_007690010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5M8"/>
    <dbReference type="STRING" id="930090.W6Z5M8"/>
    <dbReference type="GeneID" id="19128767"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96004"/>
    <dbReference type="eggNOG" id="KOG0024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_3_1"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08283">
        <property type="entry name" value="FDH_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF1">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="69"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC45270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="447" mass="49372" checksum="A398088102B59521" modified="2014-04-16" version="1">MAQNVAAKQAEKVLGHDQQKTVTQTDISNPDRDGKKYADPSGEKMKALVWMGKNDVRVQDVSKPKLLEDHDVLVRVAGSTVCGSDVHLLHGVIIQTEKGDILGHEFCGVVEQVGSKVTERKVGDRVVNSFVVSCGECRFCKQNLTTACDKTNASTVHQMLYGEKLGGIFGYSHFVGGYAGGQAEYVRVPLGDQNLLKLPDSIPFEKGLYLSDVLPTSYHSVSDTGVYEGDSVAIWGLGPIGFMACVWAFKKGAKRVIGIDNNWRTEFAKKKIPGLETINYEELKNQSIPAKIHEMVPGGVDVCIEASGGEYAKTWTHKLELASGMEQDTSEMVNECIYSTRKFGRVGIIADYVGFTNHFNIGAVMERGIRLIGCGQSPVQKYWKEILEMLEKGEVDPTIMVTHRFKIEDIAKAYYMQEKRQGGLLKCFVETKFSEPRAAGTPELKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5X5</accession>
    <name>W6Z5X5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_102113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964314">
        <property type="protein sequence ID" value="EUC39601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7C9"/>
    <dbReference type="STRING" id="930090.W6Z7C9"/>
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    <dbReference type="eggNOG" id="ENOG502QQIE">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012066_2_0_1"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
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        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21666">
        <property type="entry name" value="DUF4246_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="16"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="133"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="705" mass="80660" checksum="5428265DF9A1FEA5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7W8</accession>
    <name>W6Z7W8_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">alpha-L-fucosidase</fullName>
            <ecNumber evidence="3">3.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_10194</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.</text>
    </comment>
    <comment type="similarity">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016139">
        <property type="term" value="P:glycoside catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FUC_metazoa-typ"/>
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    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
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        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057739">
        <property type="entry name" value="Glyco_hydro_29_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ALPHA-L-FUCOSIDASE-RELATED"/>
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    </dbReference>
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        <property type="entry name" value="Alpha_L_fucos"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025618706" description="alpha-L-fucosidase" evidence="7">
        <location>
            <begin position="25"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 29 N-terminal" evidence="8">
        <location>
            <begin position="154"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC39781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="619" mass="68615" checksum="2EAD8F33E1DBFBCF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z802</accession>
    <name>W6Z802_COCMI</name>
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        <recommendedName>
            <fullName evidence="13">Protein SYS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_100239</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYS1 family.</text>
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        <property type="protein sequence ID" value="EUC43674.1"/>
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        <property type="nucleotide sequence ID" value="XM_007691623.1"/>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081382_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019185">
        <property type="entry name" value="Integral_membrane_SYS1-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952:SF0">
        <property type="entry name" value="PROTEIN SYS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09801">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="155"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC43674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="22534" checksum="85FD7EA4BC7E2418" modified="2014-04-16" version="1">MPRRRRPPRPGALADLSPIRILSQIVLLQLAYYACAGILILFTALVAGKEVSLDLLFNWQSLSGDTTVGWTLGLVWMLNSLACAIFILLLIARSKLVLDFAFTVHFIHLVVTSLYTHAIPANLFWWALQICSATLMTSLGVWACQWRELRPINFGSKTPARPQPQPQPAAEEEGGESRGRGRGRGRDGAGEYEMVGMNEGDNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8D6</accession>
    <name>W6Z8D6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_31012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964217">
        <property type="protein sequence ID" value="EUC39956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693530.1">
        <property type="nucleotide sequence ID" value="XM_007695340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8D6"/>
    <dbReference type="STRING" id="930090.W6Z8D6"/>
    <dbReference type="GeneID" id="19121785"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31012"/>
    <dbReference type="eggNOG" id="KOG2551">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051938_2_2_1"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="213" mass="24291" checksum="9AF20F2136CE6118" modified="2014-04-16" version="1">MSRKILLLHGYQQNAEIFRTETSTVQKIIGETFKTETKLEYVEAPFDAGETMSGMRIRSWWDMKAIDEFDRTHATLRYVAEILEKNGPFDGFIGFSQGGALAAIVAGLLERPPADRPAFFNTTHPPIHFIVSYSGYREHHQALQPYYENKISTPILHFINSDDPIVTEDRCVRLIERCTDTDGRIVSYSSPFHRIPSSKMARKALKSFLSEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8T0</accession>
    <name>W6Z8T0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Epoxide hydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_60917</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964199">
        <property type="protein sequence ID" value="EUC40096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693394.1">
        <property type="nucleotide sequence ID" value="XM_007695204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8T0"/>
    <dbReference type="STRING" id="930090.W6Z8T0"/>
    <dbReference type="GeneID" id="19124834"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_60917"/>
    <dbReference type="eggNOG" id="KOG2565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_2_1"/>
    <dbReference type="OrthoDB" id="3694869at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="5">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="390" mass="43775" checksum="CBC9681B46B28955" modified="2014-04-16" version="1" fragment="single">YQPRPYNVSIDPSLIELARQKASIFRPTVDTSATAWFDGPPAADIESIATYWAEEYDWRAIQNSINTNFSHFYTTVPPPSEAYNESVSLHFIHQRSARLDATPILLLHGWPSTALEWASMIPRLVSPDNSSEPGFHIVAPDIPGFGFSPALNSSRVGVGRTEYATMFAALMRQLGYKKYAVYSTDMGTTIALGLVVNHAESIMQHITDFYMTFPSPSDQARYASYQTSEEENQYIGSFSSFLDTHSGYSAIQSTYPSSLAYAMNDSPVGFLAWVYHLSSTMNDRSYEKAEIITNTLLLWHQGVYSNIRCYKELFSSSMFLPDKNFTVPTSVLQFGGLKLYPELGRLNYVPLEWVKRTANVTYFARESEGGHFPAVTVPDLVVKHIRASFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9K0</accession>
    <name>W6Z9K0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_92818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687069.1">
        <property type="nucleotide sequence ID" value="XM_007688879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9K0"/>
    <dbReference type="STRING" id="930090.W6Z9K0"/>
    <dbReference type="GeneID" id="19128153"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92818"/>
    <dbReference type="eggNOG" id="ENOG502SRWN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_325434_0_0_1"/>
    <dbReference type="OrthoDB" id="30417at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="839"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="871"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="896"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="909"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="931"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="974" mass="104971" checksum="D256E1599F3BA538" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9M0</accession>
    <name>W6Z9M0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_92192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686783.1">
        <property type="nucleotide sequence ID" value="XM_007688593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9M0"/>
    <dbReference type="GeneID" id="19128027"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92192"/>
    <dbReference type="eggNOG" id="ENOG502T36I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_976564_0_0_1"/>
    <dbReference type="OrthoDB" id="3658469at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="285" mass="32843" checksum="190B928B52FEC3E4" modified="2014-04-16" version="1">MHESHASTNNDFLPIQSERHMDRRASPPSRDSSVMNIFSRLPRELRNRIYIFCFEGSYDNEVIVRRAALGRTYRFTHLIREPCGQYSYRWIEDPVSACLSKKGWDFNLAREMLECYYWTRTFKFAHHEMCLLEPFLGTDGFGFGMTPAVYARRLQIQIQPLLFAFLLPDNRKIEEQRFCSAIEALGMIQTARTEIAIEVDLGQASLSDADYEHFLDAATKFTIQIQSLVDALKKKGLRISLRVIGSQLQFETRTNASESMATSSAALKSPALPMSQRSFHKALRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9T9</accession>
    <name>W6Z9T9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_108766</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964163">
        <property type="protein sequence ID" value="EUC40471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693020.1">
        <property type="nucleotide sequence ID" value="XM_007694830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9T9"/>
    <dbReference type="STRING" id="930090.W6Z9T9"/>
    <dbReference type="GeneID" id="19119306"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108766"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_3_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF238">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886786" description="FAD-binding domain-containing protein" evidence="6">
        <location>
            <begin position="21"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="5"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC40471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="429" mass="47503" checksum="5228EE97F8F5335F" modified="2014-04-16" version="1">MSVRLDIIIVGAGLSGLAAAVQCALSGHSVTVLEAAKELAEVGAGLQLTPNATRLLQQWSVYDTIRDQVCEPTTLTVYNYRGETLAHENHFGTNIRRKYGAPFSDCHRVDLQQALVGRAKELGVHVMLDAKVNGIDFGSAPGDKARVKSHQGQAYETDLIVGADGLWSSCRSTMLGRNDNPLPTGDRAYRIVLSVDQIGDPKLKEMVQTPACRFWAGPDAHAVAYSIRGGNMYNVVLLVPDDLEEGVARTRGNLDEMRRLFEGWDPVLTQLLECVDRVDKWKLMHRAEMDSWVNPQNNLVLIGDSCHPMLPYLAQGANSSIEDGAVLGLLLDPEHYKSRLQLPDTLQLFQQLRKARSESIARETFKQRKDFHLRDGPEQAIRDATMLRQLGKSPAGAFPSRWTCPEVQPWLYGYNAAEEVAAAMRARTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9V0</accession>
    <name>W6Z9V0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_108694</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964161">
        <property type="protein sequence ID" value="EUC40486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692992.1">
        <property type="nucleotide sequence ID" value="XM_007694802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9V0"/>
    <dbReference type="STRING" id="930090.W6Z9V0"/>
    <dbReference type="GeneID" id="19119293"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108694"/>
    <dbReference type="eggNOG" id="ENOG502SJ6K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019101_2_2_1"/>
    <dbReference type="OrthoDB" id="3903189at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF149">
        <property type="entry name" value="UBID FAMILY DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="23"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="433"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="496" mass="55334" checksum="8B837C79D82B8201" modified="2014-04-16" version="1">MTLPFNQESWIWYTCAVCMIGARLISRKILFRSIKGLQFDDYIMGLFVTAAYTVLLVYSNKWLKVDSNLEPPGFDFGVLSPEELSRRVYGSKLVIVVEQMQLAVLWSCKACLLIMYHRITRTALHYENIAIKVLAVYTAIGFVVIEVLYFSAWCRPFSAYYAVPTSSLQCTTLVNHRITKAVFSISSDLSMLFISLPMLVRSLLPMRRKIILCGIFSLGLFVVIASIANAYSSFTNPYKATWISWYVRESSTAILVANLPFTWNVLKEFFEVGQFDVSPPAWTYHSARTARGRTTTQLLNQQMGTTNRTYATSTNPSRTRRSASLVMSSIEVVPPKNSHQSDDARSDLMDEAIGLQDFAPVVLRSTDDGVKVFDLESGLVDKLDARPVSYNHVRQSNNFMAVPQTIIQDGNGGFYIDGRPISSPSMAHITVSSKRTSANSVTSLFRRPNSPVPSYSTTKTNDEGGRKDSPGISGGEVTADKGRDATDAKARSRMME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAH3</accession>
    <name>W6ZAH3_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_25040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC46985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686465.1">
        <property type="nucleotide sequence ID" value="XM_007688275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAH3"/>
    <dbReference type="GeneID" id="19120696"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25040"/>
    <dbReference type="eggNOG" id="ENOG502SWW9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_319845_0_0_1"/>
    <dbReference type="OrthoDB" id="3911405at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="752"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="400"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="565"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="794"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="942" mass="106254" checksum="68C30EBAE26882A8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB60</accession>
    <name>W6ZB60_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_24945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686312.1">
        <property type="nucleotide sequence ID" value="XM_007688122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB60"/>
    <dbReference type="STRING" id="930090.W6ZB60"/>
    <dbReference type="GeneID" id="19120667"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24945"/>
    <dbReference type="eggNOG" id="KOG1200">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="291" mass="30158" checksum="657A515BDE390BAB" modified="2014-04-16" version="1">MSSSKRVEQIAGHLNYPKGMLAGQTAIITGSGQGIGAEAAKLFAKEGAKVVVADVDAKKAEAVASEINSSGGSAIAVAGDVLDDAYIKTLISKAAEFGGGKIHIIVNNAGYTWDGVIHKMTDKQWQTIVDLHGTAPFKIVRAAAPYFRVKDGEPRNIINISSTSGLNGNAGQINYALAKAGVQGMTKTIAKEWGPQFGVRANTVAFGHIQTRLTAAKEAGAFVTTPDGEKVALGIPQAQKAAVPEGQLYADIPLRRPGTATEAASAVLAVASPLFSYVNGETIKVTGGRNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB97</accession>
    <name>W6ZB97_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxymuconolactone decarboxylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_97481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688740.1">
        <property type="nucleotide sequence ID" value="XM_007690550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB97"/>
    <dbReference type="GeneID" id="19129070"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97481"/>
    <dbReference type="eggNOG" id="ENOG502RZ3K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_2_0_1"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34846:SF9">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G03690)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34846">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21218" checksum="C382C63D130A0C92" modified="2014-04-16" version="1">MRLPYVPDPPNFTSEADKAVEQRVRERRGEKGLIALDRTLLHSPPVADGWNSFLGSIRTKTSLLTSIRETAICRVAVLNRAWYEWESHSPILSSASDVTPQQVEAVLKSPPRSPLVDILGPSLSILLAYTDAMTLDVQVPDAVFAELKKSFSEREVVEITATIAAYNCVSRFLVALDVGERNAQTGPKEGGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBQ5</accession>
    <name>W6ZBQ5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_3664</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686062.1">
        <property type="nucleotide sequence ID" value="XM_007687872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBQ5"/>
    <dbReference type="GeneID" id="19123076"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3664"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_7_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF152">
        <property type="entry name" value="OXIDASE (CODA), PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="543" mass="59964" checksum="39CB8BA9C5E0A629" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCE8</accession>
    <name>W6ZCE8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_96520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688409.1">
        <property type="nucleotide sequence ID" value="XM_007690219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCE8"/>
    <dbReference type="STRING" id="930090.W6ZCE8"/>
    <dbReference type="GeneID" id="19128867"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96520"/>
    <dbReference type="eggNOG" id="KOG3041">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062658_0_1_1"/>
    <dbReference type="OrthoDB" id="10249920at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019693">
        <property type="term" value="P:ribose phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18888">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000016">
        <property type="entry name" value="ADP-sugar pyrophosphatase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF1">
        <property type="entry name" value="ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="58"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="219" mass="24674" checksum="450E61C41D00F2C8" modified="2014-04-16" version="1">MASVNSAPRKPKIVKIEPLENKDAKWATFVKTTYTDPEGVERTWESGERLTRPKDTDIDGVGVAAILQDPAKPNDEPRIVLQKQWRPPVNATVIEVPAGLMDPGESAEMCALRELKEETGYIGELVEDQTFRISPIMFNDPGFCNTNLRMIHVTVDLSRPENRNPQPSLEDNEFIETFSVPLKSLWDECIALEKEGYAIDARVGTLAEGIEFAKRWKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCV7</accession>
    <name>W6ZCV7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688240.1">
        <property type="nucleotide sequence ID" value="XM_007690050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCV7"/>
    <dbReference type="STRING" id="930090.W6ZCV7"/>
    <dbReference type="GeneID" id="19123166"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37021"/>
    <dbReference type="eggNOG" id="KOG3851">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030742_2_2_1"/>
    <dbReference type="OrthoDB" id="5376590at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070224">
        <property type="term" value="F:sulfide:quinone oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070221">
        <property type="term" value="P:sulfide oxidation, using sulfide:quinone oxidoreductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000203">
        <property type="entry name" value="Related to sulfide:quinone oxidoreductase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015904">
        <property type="entry name" value="Sulphide_quinone_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632:SF2">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="36"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="445" mass="49253" checksum="896F928C6D2F1922" modified="2014-04-16" version="1">MNCLQKSRGWDLLSKRSAIRNLATVSLAAPAARNHKIVVVGNGSAGVAVSHQLLRKGKFTKDDIAVIDPAKWHHYQPGWTLVGGGLKDKKALRTPMDDLVDGKLKFYNKSVASFSPNNNLLTLDSGDTIHYGHLVVAPGIKIDYDSINGLSEALSNPHSPVASIYSYDYCDKVFRNIQRLKSGSAVFTQPAGVIKCAGAPQKIMWLALDHWGRSGLYQNDPKKSSINVTFATGLPSMFGVPKYSSTLDALRKERAVEGLFEHDLISISGNTATFARANSQAKVHRRFDFLHVAPKNAPHDFIKVSPLSNETGYVDVDPHSLRHRKYPNIWSLGDAANLPTSKTVAAITSQAVVVTQNVLRSLEGKDASEEYDGYTSCPLLTGDKKVFLAEFKYGGVPKETFKSWVGIDQAVPRRAFYHLKKDFFPWVYDRFHVKGRWGGPKGWIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDS7</accession>
    <name>W6ZDS7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_88436</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685434.1">
        <property type="nucleotide sequence ID" value="XM_007687244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDS7"/>
    <dbReference type="GeneID" id="19127267"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88436"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005734_0_0_1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF8">
        <property type="entry name" value="CYTOCHROME P450 2E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886923" description="Major facilitator superfamily (MFS) profile domain-containing protein" evidence="9">
        <location>
            <begin position="18"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="675"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="742"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="772"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="855"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="895"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="968"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1021"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1050"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1083"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1189"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1221"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="831"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1114"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="523"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1116"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1266" mass="138270" checksum="E9F4A81462EC973B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE92</accession>
    <name>W6ZE92_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_105073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964083">
        <property type="protein sequence ID" value="EUC41846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691627.1">
        <property type="nucleotide sequence ID" value="XM_007693437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE92"/>
    <dbReference type="STRING" id="930090.W6ZE92"/>
    <dbReference type="GeneID" id="19118628"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105073"/>
    <dbReference type="eggNOG" id="ENOG502QUMF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012587_0_0_1"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="797"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="837" mass="91235" checksum="B50B36BCA22AF55C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEF2</accession>
    <name>W6ZEF2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_36398</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687568.1">
        <property type="nucleotide sequence ID" value="XM_007689378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEF2"/>
    <dbReference type="GeneID" id="19123014"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36398"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="OrthoDB" id="6509908at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="95"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="485" mass="52108" checksum="E52B8F295E3D8035" modified="2014-04-16" version="1">MDHTTPSCPKKTSYAAPASSASLNLEEKPDNQPSLASSDSVHSSGPIAVDEHPQHEKHVTESSSTQESGADLEPVRSAHPSVRDVSKIPNGGLWAWLQVLGGFFLLFNSWGIINTFGSYQAYYETTLLPNSSPSSISWIGSIQAFLLMMVGALTGPIYDAGYFRELLLVGSFLLVFGQMMLSLCHAYWQVLLAQAFCIGIGTGCLFVPSVAILSTYFSTRIGTVIGIAASGSSFGGVIYPIVFHKLLPQIGFAWTTRVLGFIIFATMVIPNVCMRVRVLPAKSRSLLDLRAFLIPAYSLQVTGFFLGFMGLYMPFFFGQVYAIQERITSEGLAFYLLAVMNSTSMFGRILPNLLSDKIGPINVVIPCALISGILCICFMAVSSSAGIIVMMAFYGFFSGSFVSLPPTIIVHLSADARDKIGTRFGQSFGIVAIGLLVGTPIGGAIQEHGGFDDLWTYGGCLLFSSAALLTCARVAFKGRGLMVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFH4</accession>
    <name>W6ZFH4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histone deacetylase interacting domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_23532</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684709.1">
        <property type="nucleotide sequence ID" value="XM_007686519.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZFH4"/>
    <dbReference type="GeneID" id="19120455"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23532"/>
    <dbReference type="eggNOG" id="KOG4204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001360_2_4_1"/>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000001">
        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="9">
        <location>
            <begin position="838"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="25"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="217"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="388"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="644"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="719"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1120"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1571"/>
            <end position="1599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="146"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="457"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="493"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1120"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1132"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1151"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1175"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1571"/>
            <end position="1585"/>
        </location>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48760.1"/>
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    </evidence>
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    </evidence>
    <sequence length="1599" mass="180345" checksum="06C992766361483B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG50</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="Salamov A."/>
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                <person name="Han J."/>
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            <dbReference type="RuleBase" id="RU003968"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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    </evidence>
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</entry>
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    <name>W6ZGY8_COCMI</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
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    </feature>
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            <end position="41"/>
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    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
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    </evidence>
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        <source>
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    <sequence length="456" mass="48855" checksum="4B0CB3C96B1CF0E5" modified="2014-04-16" version="1">MKTYIFAVALAATAAAKPAEQKRASNSKITPVTVKGNAFWAGNERFYIRGVDYQPGGASDAKDPIADEDGCKRDISKFKELGINTVRVYTVDNSANHDTCMGLLADAGIYLALDVNTPKYSINRANPQKSYNKVYLQSLFATVEMFSKYDNTLLFFSGNEVINDDKTTNCAPYVKAVTRDLKSYMNARGLRKVPVGYSAADVESNRYEMADYMNCGDDAIRSDFFGFNDYSWCDPSSYNTSGWNIKVEKFSNYSIPIFLSEYGCNTNTRKFEEVKALYDPKMTKCYSGGLVYEYSQEESKYGLVEIDGNSVNELPDFTALKSAFAGTPNPTGDGGYLSNGQASQCPPQSKTWDVTLKSNELPSLPDGAKDYFDKGAGAGPGLKGDGSQDAGSSTTDIGDAGAGAVTSGGKTPTSTASPTKSAGAAANVRPMSFSLAPIVCGAVVLASSLFGGALVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH73</accession>
    <name>W6ZH73_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">DUF4048 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
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        </location>
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        </location>
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            <begin position="598"/>
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        </location>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13257"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC46764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="609" mass="66906" checksum="FD36614D42CEEF4E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH79</accession>
    <name>W6ZH79_COCMI</name>
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        </submittedName>
    </protein>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964045">
        <property type="protein sequence ID" value="EUC42901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692375.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19118049"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102279"/>
    <dbReference type="HOGENOM" id="CLU_2873711_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="64" mass="7227" checksum="B9B0C15E1DB47941" modified="2014-04-16" version="1" fragment="single">CLFCGTSRGKNGVARWERCVCGVSEGLVTHRLRVGCICLLMIMMMMMFHKVVRFGRQGSQMEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI90</accession>
    <name>W6ZI90_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_28291</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the cytochrome c family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690255.1">
        <property type="nucleotide sequence ID" value="XM_007692065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI90"/>
    <dbReference type="STRING" id="930090.W6ZI90"/>
    <dbReference type="GeneID" id="19121277"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28291"/>
    <dbReference type="eggNOG" id="KOG3453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060944_3_0_1"/>
    <dbReference type="OrthoDB" id="449280at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000001">
        <property type="entry name" value="Cytochrome c iso-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10 12" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="13">
        <location>
            <begin position="6"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC43216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="108" mass="12072" checksum="BA91B3F421202B11" modified="2014-04-16" version="1">MGYEKGDAKKGANLFKTRCAQCHTLKAGEGNKIGPELHGLFGRKTGSVAGYSYTDANKQKGIEWNHDTLFEYLENPKKYIPGTKMAFGGLKKPKDRNDLITFLEEETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIG2</accession>
    <name>W6ZIG2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginyltransferase</fullName>
            <ecNumber evidence="2">2.3.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_7250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the R-transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.8" evidence="2"/>
    <dbReference type="EMBL" id="KI964033">
        <property type="protein sequence ID" value="EUC43326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690154.1">
        <property type="nucleotide sequence ID" value="XM_007691964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIG2"/>
    <dbReference type="STRING" id="930090.W6ZIG2"/>
    <dbReference type="GeneID" id="19125230"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7250"/>
    <dbReference type="eggNOG" id="KOG1193">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020349_0_0_1"/>
    <dbReference type="OrthoDB" id="74183at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyl-tRNA--protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="ARGININE-TRNA-PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367:SF1">
        <property type="entry name" value="ARGINYL-TRNA--PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-end aminoacyl transferase N-terminal" evidence="6">
        <location>
            <begin position="12"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="N-end rule aminoacyl transferase C-terminal" evidence="7">
        <location>
            <begin position="141"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="426" mass="48986" checksum="46C41899DFA4EE70" modified="2014-04-16" version="1">MQSSATPAGASFYFLSKRLTVEVYQLLVDRGWRRSGTLFYKPDVLRHCCPHYTIRLPVDSFKPSKDQRKAVNHWNDHVLGESYIKEASRLYPLSKQEKARLKNTFDLVREVHRAELQNVKQPPEPAHRFEVTLEPAVFTAEKYDLFKNYQQTVHKEPSSQISQSGFRRFLCDSPLQQTSRTVNGKEQLLGSFHQCYRLDGRLIAMGVLDLLPHCVSGVYMLYHSDVAEWQFGKLSALREAALALEGGYEYYYMGYYIHTCTKMKYKGDYKPQHVLDPESYEWHPLDGELRSLLDKKKYVSLARERRRQKEQASAAKQTDGADTAEQDDYSDFPLVSPTEAADAWMNGMSLFDLKMPGVMTAEEIEEKIDLATMPFRAGSRLVELQDLVSWDNSDLRDPHSIQGMVGEMVACMGPEVAWQIVVQLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIN0</accession>
    <name>W6ZIN0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_83661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683702.1">
        <property type="nucleotide sequence ID" value="XM_007685512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIN0"/>
    <dbReference type="GeneID" id="19126306"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83661"/>
    <dbReference type="eggNOG" id="ENOG502QQEE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_386866_0_0_1"/>
    <dbReference type="OrthoDB" id="3936275at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="593" mass="61864" checksum="76FD467D17D38AC3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIP9</accession>
    <name>W6ZIP9_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_83713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIP9"/>
    <dbReference type="GeneID" id="19126310"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83713"/>
    <dbReference type="HOGENOM" id="CLU_2654122_0_0_1"/>
    <dbReference type="OrthoDB" id="4788795at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="76" mass="8337" checksum="D96B765CCDF71E3A" modified="2014-04-16" version="1">MLVRNIPPTTLATLAFCLPDNLKHSGACTPLNPYCGGDPASRLLNWKFTVTTFCNSGHVDSAWWEATRNQFGAVHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIY0</accession>
    <name>W6ZIY0_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_83175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685385.1"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="5305647at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059009">
        <property type="entry name" value="Znf_C2H2_17_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059095">
        <property type="entry name" value="Znf_C2H2_17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF24">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26177">
        <property type="entry name" value="zf_C2H2_17_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="zf_C2H2_17_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="625"/>
            <end position="652"/>
        </location>
    </feature>
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        <location>
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            <end position="691"/>
        </location>
    </feature>
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        <location>
            <begin position="491"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="796" mass="88265" checksum="1FEAA68CD1D54A76" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJL6</accession>
    <name>W6ZJL6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_82493</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJL6"/>
    <dbReference type="STRING" id="930090.W6ZJL6"/>
    <dbReference type="GeneID" id="19126066"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82493"/>
    <dbReference type="eggNOG" id="KOG1944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049109_8_0_1"/>
    <dbReference type="OrthoDB" id="10267969at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF50">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YOR292C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="256" mass="29140" checksum="DA165756199BC9D6" modified="2014-04-16" version="1">MNSTRHRLLYQLNSRWIYGKIPLLHSIVFLLQMAAVSLLTRKYNQYYAARPVLTTMITNAVLGGIADTVAQTLTAVRERAVRKKGGPGKDDFLAIEIHDLDKRNPFNENDLIPDSKKLPPPFDFERTTRFMSYGFLMSPIQHRWFRFLSATFPVTKTATWMPALKRVAFDQFLFAPAGLAAFFTFMTIAEGGGKRAVQRKFQDVYVPALKANYMVWPAVQIINFRVMPIQYQIPFVSSVGIAWTAYLSLTNSAEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJN5</accession>
    <name>W6ZJN5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683110.1">
        <property type="nucleotide sequence ID" value="XM_007684920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJN5"/>
    <dbReference type="GeneID" id="19129089"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_976"/>
    <dbReference type="HOGENOM" id="CLU_2721845_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="72" mass="8240" checksum="FE5C807DA20D825E" modified="2014-04-16" version="1">MTDKLVAANVWSARSDLTPWKRQPAPEEETTMNQWIKKPPVHILGGSAEEMNNRKSAKWHPQVTMDKPKSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK68</accession>
    <name>W6ZK68_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_22078</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682998.1">
        <property type="nucleotide sequence ID" value="XM_007684808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK68"/>
    <dbReference type="STRING" id="930090.W6ZK68"/>
    <dbReference type="GeneID" id="19120177"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22078"/>
    <dbReference type="eggNOG" id="KOG2495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019845_6_2_1"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="426" mass="46296" checksum="4953D5639548EA13" modified="2014-04-16" version="1">MSTETILILGGSFAGISAAHFLLRHVVPQLPKKDDVTYNVTMVNPSKDLWWRFASPREAVSKQMMPSDKTFYPIEPAFAYASSKFRFIQGMATHVDAAGQIVSVETASGEQQSIPYAALVIATGFTTPSPLFTQATDREALEKVHAAFQESLKTAKDVIIGGGGPVGVETAGEIAEMLNGKPGFMASAPKNPKAQIRVFVADRQLLPLLRPAIGQTAEQFLKRLGCNITYDVRVIGSSKMSEGEGGKTRVDLSNGEILETDIYIDATGTRPNTGFLPKEWLDSRNRVACNAKTLRLEHESASPRVYVVGDVGSYTRGGVMDMYDAVPVAMTNLKNDLLAHLTGEPHKGDRHYVANTKEQQVVPIGTQKGVGAFNGFRLPSQMVWFIKGRDYMISQLAQATLRGDQFKKEGKWTPVQETGKAGLGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL54</accession>
    <name>W6ZL54_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_87923</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CYC8/SSN6 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685258.1">
        <property type="nucleotide sequence ID" value="XM_007687068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL54"/>
    <dbReference type="STRING" id="930090.W6ZL54"/>
    <dbReference type="GeneID" id="19127158"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87923"/>
    <dbReference type="eggNOG" id="KOG1124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006762_2_1_1"/>
    <dbReference type="OrthoDB" id="418911at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017053">
        <property type="term" value="C:transcription repressor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000403">
        <property type="entry name" value="General transcriptional repressor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000078">
        <property type="entry name" value="Transcriptional corepressor Cyc8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051630">
        <property type="entry name" value="Corepressor-Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017:SF1">
        <property type="entry name" value="LD02225P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4 9" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="49"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="117"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="190"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="299"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="333"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="415"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="519"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="580"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="626"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="713"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="750"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="798"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="858" mass="95158" checksum="21D5D9482B86136E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLV3</accession>
    <name>W6ZLV3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLV3"/>
    <dbReference type="GeneID" id="19121129"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_275"/>
    <dbReference type="eggNOG" id="ENOG502SSV2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075337_0_0_1"/>
    <dbReference type="OrthoDB" id="4757095at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790:SF9">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="4"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="160" mass="19079" checksum="96F7AC48DDA237B5" modified="2014-04-16" version="1">MISYSEAVEYLYNSNKFFISTDVEDYPTMGYLPFFIQPQRMNQITNLRIDWDLDRHGFFQADLMPQVHRDEWDRTWDVLGRMSGLRTLHIRLFFFLDLWLQCYGDFWEQNGKALLKPITTMTAPRDFTVTLPDWRCSTDLDVGKSRCVFQLPERSEDSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM15</accession>
    <name>W6ZM15_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_87138</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684998.1">
        <property type="nucleotide sequence ID" value="XM_007686808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM15"/>
    <dbReference type="STRING" id="930090.W6ZM15"/>
    <dbReference type="GeneID" id="19126996"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87138"/>
    <dbReference type="eggNOG" id="KOG0369">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_2_1"/>
    <dbReference type="OrthoDB" id="196847at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45007">
        <property type="entry name" value="CARBOXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G07570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45007:SF1">
        <property type="entry name" value="CARBOXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G07570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="9">
        <location>
            <begin position="8"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="123"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="572"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="655" mass="71060" checksum="91D2A31BEDEFF955" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNJ9</accession>
    <name>W6ZNJ9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lytic polysaccharide monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_5637</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963990">
        <property type="protein sequence ID" value="EUC45146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688330.1">
        <property type="nucleotide sequence ID" value="XM_007690140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNJ9"/>
    <dbReference type="STRING" id="930090.W6ZNJ9"/>
    <dbReference type="GeneID" id="19124682"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5637"/>
    <dbReference type="eggNOG" id="ENOG502RY3D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_1_0_1"/>
    <dbReference type="OrthoDB" id="4849160at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
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        <property type="entry name" value="AA9_LPMO"/>
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    <dbReference type="PANTHER" id="PTHR33353:SF34">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
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        <property type="entry name" value="AA9"/>
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    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="6" id="KW-0732">Signal</keyword>
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            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
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        <location>
            <begin position="22"/>
            <end position="342"/>
        </location>
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            <begin position="22"/>
            <end position="236"/>
        </location>
    </feature>
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            <begin position="249"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="268"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="342" mass="35558" checksum="1230E74A8B9AFA1E" modified="2014-04-16" version="1">MYKSLVSTITAIAALAATATAHGSLTGVSLNGVYEQGFLLEYYYAMQQGGKVPEHLGWYAENLDNGFVEPSKFGTGDIICHKAGSPKGSSDTMGKIPAGGKIDFHWNTWPASHVGPVLTYAASYTGDLQSVKKEELKWFKIEGVGYENGEWAAVKMIANNNTWTTTVPTSLAAGKYVFRHEIIALHAAGQENGAQNYPQCVNIEVTGSGTEKPEGVVGTKLYTSTDPGIKFDVYQGKLDSYVVPGPPAMAAGSGSGSGSGSGSGSGSGTAPAPTKPSPSSAPSTPSPTPSASAAPVTPEAQEPAPSSGNLPETFTLETFITWLEGKASSSASKARRHARAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP31</accession>
    <name>W6ZP31_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_78650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963986">
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689972.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19125416"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_78650"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="3801338at2759"/>
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    </dbReference>
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            <begin position="217"/>
            <end position="255"/>
        </location>
    </feature>
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        <location>
            <begin position="217"/>
            <end position="252"/>
        </location>
    </feature>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="31495" checksum="80227C431374906D" modified="2014-04-16" version="1" fragment="single">SEGSSIAIVDQCYDNLLEMIRPQRQALLTGPRITIHIGNTSVSDIYKRSAMAASSVLHRHFTNHPNSLECRFSRSQINPGAVRLLLIKWMREACNEFEAHAVPYQKTFFEDIAVLRAARLLGMERYCSHILGAYTTYLKSELPSYEEIVIIEQNATSDKDPLWTSMVNHLCHDRFKGLIPDVDEFEEFLETHDRLKTAMEAADAYFAGYAKRYANARESERRQRRQQNEAEKRERIEREKRTAQSLKKKLDEAGSGLMTVTADEAEMLRGRAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPA9</accession>
    <name>W6ZPA9_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
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        <name evidence="2" type="ORF">COCMIDRAFT_95472</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963984">
        <property type="protein sequence ID" value="EUC45451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPA9"/>
    <dbReference type="GeneID" id="19128663"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95472"/>
    <dbReference type="eggNOG" id="ENOG502TBWJ">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_562574_0_0_1"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
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        <location>
            <begin position="110"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
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        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
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        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="53167" checksum="579CD4A16EE90B76" modified="2014-04-16" version="1">MVTQRRYSVTGQTPPDDAEAMKARSPKLQSLDTSVQAPPCGYCDAAAELSASGDDGASEQRRGRKMGPNGTIVRTSSKRSATQLPSPSSPSQQLPQKIPRYRLCHDEHADVDMDSDTDSGSDGTDGLGEGSELDDDHGLESRATSVPSTPDHSLGCSALGLPEATRLEGLRLYAEERPDDEHMEDYALSPPHSRNNSVNRTQFDGASVLQAEWAAHIAMHKDKSETVHIENIQNIEPIENAEPVQNIEPAEDIQTTSTDIGQPLPTDTTHDPLTFITLPPEIRHQIYRSCENLVVDKPLVYCISTFNGEMQHPLASVSRLVRSEALAIFYSYNLWVIKVEFRMMYEAFRDWIIRLGEGAGLLRLIALSVRGSLFKPKKSHGQSVLIHGHLVQLAPGIIGPAAGSREELYCPPDGDASFRIDLSEKHAGGMVQIVRNDGTSEAGEKARVYLSKMVGGLWEKRRAGTLNGQDWITMVDGFLSFIGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPS0</accession>
    <name>W6ZPS0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_36703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963981">
        <property type="protein sequence ID" value="EUC45611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687885.1">
        <property type="nucleotide sequence ID" value="XM_007689695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPS0"/>
    <dbReference type="STRING" id="930090.W6ZPS0"/>
    <dbReference type="GeneID" id="19123095"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36703"/>
    <dbReference type="eggNOG" id="KOG2043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032842_0_0_1"/>
    <dbReference type="OrthoDB" id="342264at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="335"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="564" mass="62493" checksum="F557128D973719E1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPS8</accession>
    <name>W6ZPS8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Class II aldolase/adducin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963981">
        <property type="protein sequence ID" value="EUC45621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687911.1">
        <property type="nucleotide sequence ID" value="XM_007689721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPS8"/>
    <dbReference type="STRING" id="930090.W6ZPS8"/>
    <dbReference type="GeneID" id="19128580"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95079"/>
    <dbReference type="eggNOG" id="KOG3699">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006033_1_0_1"/>
    <dbReference type="OrthoDB" id="3238794at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000009">
        <property type="entry name" value="Class II aldolase/adducin N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF39">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="93"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="328" mass="36425" checksum="7343CA07E33860DE" modified="2014-04-16" version="1">MSTTYLRSRLLLRTYSPFKFRRASTPFYSNRCLATSSSPYNASVAAGIRVDHAEEIDNQTVAAMGRTKAGKSLKVRRYPTFTRLEDERLYRKQHLAAAYRVFASRGFDEGVAGHISVRDPIMTDHFWLNPLSTHFSLMRVSDLILVNEEGEVVEGDQPINAAAFAIHSAIHKRRPEVHAACHAHSVHGKAFSAFGRELDMITQDSVRFYKSHGVYNQFGGIVLASEEGERIADALGDGKAAILQNHGILTVGKSVDEAAFWFLSLDKTCQAQLLVDAAAAGSRHKPKIIPESEAAETYKQVGTPEKGWLAFQSYYDEILAKTNGDFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ08</accession>
    <name>W6ZQ08_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_32997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683859.1">
        <property type="nucleotide sequence ID" value="XM_007685669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ08"/>
    <dbReference type="GeneID" id="19122224"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32997"/>
    <dbReference type="eggNOG" id="ENOG502SKU0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054245_0_0_1"/>
    <dbReference type="OrthoDB" id="427711at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="160"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="294" mass="31319" checksum="B76597187CF5A5DA" modified="2014-04-16" version="1">MTVDDPTNTPAPFSYDAGSRSRLAAPSGQVAYTSQPFAPARRAFFDPWNSSSTGHQRAENRLSGSTSWRASRNVKLGEQFKGGRHGGKRIADTVGAGSDDSANVGLHSLRTGGQKSFAEVWAAGKSCKQASENKEPKTEPEFEPDTNSESNVCEDASVPLEKQLFAGLCFYLNGSTAPLVSDHKLKQILATHGATHSIALGRRTVTHVILGTVNERGGAGGGLAATKLQKEIVKAGGKTVKFINADWVLDSIKANRRLPESRYSPLKFAPKSQSTILNAISAMATSKAKKYISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQG0</accession>
    <name>W6ZQG0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_56457</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687533.1">
        <property type="nucleotide sequence ID" value="XM_007689343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQG0"/>
    <dbReference type="GeneID" id="19124685"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_56457"/>
    <dbReference type="eggNOG" id="ENOG502SQBC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_687253_0_0_1"/>
    <dbReference type="OrthoDB" id="3918601at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="29"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="332"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="361" mass="40530" checksum="E4596B365940C399" modified="2014-04-16" version="1" fragment="single">MTSIQGHMDAIKLVSWTLAVAVVVVLITRQIAKTIVFRKVGLDDSLILIASIFAISLSATVLILTANGRAMSFSLTFSQANILSKGYYTSELFYVSGVCFPKFSILVLFFNIVASRQFLRRVVLALGIFISTWTLVSLVTIAFQCELPRPWKTSSPHCLNFRIFWVIYCAFDVLTEIALVTIPMKIVASLQMPLCRKMAVVSCFSPRLLVIAGTIVRTIWVYPTIPQRHDHHRIWEPLVAMQVHLCMSIITASIPFMVPYCRELSHRLQGSTSMRSSMHLQDKKVGHPTPIWFRRHLKKRDAVTRNSDLEGAIHYELVPRVSPGIPFARSPSPMASGALQMSPKQKSSVKGLNIHIPHRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTV4</accession>
    <name>W6ZTV4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_80740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682612.1">
        <property type="nucleotide sequence ID" value="XM_007684422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTV4"/>
    <dbReference type="GeneID" id="19125722"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80740"/>
    <dbReference type="eggNOG" id="ENOG502SJ96">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052363_0_0_1"/>
    <dbReference type="OrthoDB" id="5283561at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="55061" checksum="F0B38FA2EC18E27D" modified="2014-04-16" version="1">MNINQFPYEILSQILLEVTKANVREGPTYTFGLQQAPLPLERAKLQRYVRGPVPPELLKWDATATLRSVCWRWHEWALEHSIKDVYIRRWKGGERWAELSNRRESYPLYELIDRPTGTAVYRDPFASLKRTIKICNDYPQVASKIKRMWVHGFYTAETDRLIFDCLRNCVNLTSLSIPWTTIRHVDAKAWRAMLTGSGKSLQSLELQCVDPTSQQAADKDNLVDLEPLQSVNFSQLRRLKIFGDTSFMPITDNDLFAIARTATQLEEFHLTCNSSITIDGVMAIVKASRQTLRVLEHSPRSQDGFWHPHPGSPSDSEHLCDTFRNCPKLETLSISLPSVCSHLFSNEDAKFAGDLQVRALHLCEHEHGRSTHEATDALQKLLEQARRFIRLRAESAIPRELYIELFFADCIFEPGFQAVHGDFSLAQISSEGYWPQNVEFSGKGPYGSTGLYGKEEEAQFQRIHEADFLAGVHRRLHSIQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUJ9</accession>
    <name>W6ZUJ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar import/degradation Vid27 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_79750</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682168.1">
        <property type="nucleotide sequence ID" value="XM_007683978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUJ9"/>
    <dbReference type="STRING" id="930090.W6ZUJ9"/>
    <dbReference type="GeneID" id="19125539"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79750"/>
    <dbReference type="eggNOG" id="KOG2395">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007002_0_0_1"/>
    <dbReference type="OrthoDB" id="10251113at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040458">
        <property type="entry name" value="Vid27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013863">
        <property type="entry name" value="VID27_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040979">
        <property type="entry name" value="Vid27_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040768">
        <property type="entry name" value="Vid27_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913:SF0">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08553">
        <property type="entry name" value="VID27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17748">
        <property type="entry name" value="VID27_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17747">
        <property type="entry name" value="VID27_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vid27 N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Vid27 PH-like" evidence="3">
        <location>
            <begin position="247"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar import/degradation Vid27 C-terminal" evidence="2">
        <location>
            <begin position="426"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC51199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="804" mass="91017" checksum="A400302C3F86B408" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWY5</accession>
    <name>W6ZWY5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative peptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_34215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the ZPS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685150.1">
        <property type="nucleotide sequence ID" value="XM_007686960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWY5"/>
    <dbReference type="STRING" id="930090.W6ZWY5"/>
    <dbReference type="GeneID" id="19122513"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34215"/>
    <dbReference type="eggNOG" id="ENOG502RTN8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048223_0_0_1"/>
    <dbReference type="OrthoDB" id="4689212at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11307">
        <property type="entry name" value="M35_Asp_f2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000043">
        <property type="entry name" value="Major allergen Asp F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029482">
        <property type="entry name" value="HRXXH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039124">
        <property type="entry name" value="PRA1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39399">
        <property type="entry name" value="PROTEIN ZPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39399:SF1">
        <property type="entry name" value="PROTEIN ZPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13933">
        <property type="entry name" value="HRXXH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887752" description="Putative peptidase domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Putative peptidase" evidence="5">
        <location>
            <begin position="14"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00060890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="304" mass="32546" checksum="34856406177110BC" modified="2014-04-16" version="1">MVARVSALLLLGASAVLAGPIAPRDTFTITTSENAQISVGDSTWNAGAVDSFPIHASCNATQRTMLQKGLNEAVVLARHARDHILRWGNESHIYTKYFGDSPTGEPIGWYTKIADGDKAGILFRCDDIDGNCHQDGWAGHWRGSNASSETVICDLSYELRKPLESMCMYGYNVANGATNYFWASDLIHRLLHLPPVGEGVVEHYTNEEEEKYPSVINLAKNNATYSARDSDTIQYFALEAYAYDIAVPGVGCPGRYAAPEESPAATSSATPSATSAATSAAASAAASEAVAAPAEACEPHNDHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYX1</accession>
    <name>W6ZYX1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_33602</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684514.1">
        <property type="nucleotide sequence ID" value="XM_007686324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYX1"/>
    <dbReference type="STRING" id="930090.W6ZYX1"/>
    <dbReference type="GeneID" id="19122361"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33602"/>
    <dbReference type="eggNOG" id="ENOG502R4GW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024451_0_0_1"/>
    <dbReference type="OrthoDB" id="2117459at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047168">
        <property type="entry name" value="LEC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024554">
        <property type="entry name" value="LEC1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024555">
        <property type="entry name" value="PX-associated"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185:SF2">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12825">
        <property type="entry name" value="DUF3818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12828">
        <property type="entry name" value="PXB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX-associated" evidence="3">
        <location>
            <begin position="4"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="165"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="704" mass="78713" checksum="36CF3E8394E021F9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1W1</accession>
    <name>W7A1W1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_32593</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683405.1">
        <property type="nucleotide sequence ID" value="XM_007685215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A1W1"/>
    <dbReference type="GeneID" id="19122135"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32593"/>
    <dbReference type="eggNOG" id="KOG4754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039184_1_0_1"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF54">
        <property type="entry name" value="PHOSPHATASE SPAC5H10.03-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="27172" checksum="3802353B253166DD" modified="2014-04-16" version="1">MAPKIHLVRHAQGEHNATRDYSIRDAVLTAKGKEQCRALSAAFQHHDEIETVFASPLRRTIQTAALSFGRVLSRPEVPFVLLPALQEVSNIGCDVGLADSAADLQRLLPDLFEAGEIDFDLSKIDASAVTPGWNSKDGYWAYEKTAISKRAADVRSWLFQRPEAQVLVVTHGAFAHFLTEDWDVEDPMLGTAYKNCEHRVFVFTPDSTAAKAHVEETWESRRGRSTVEVEKDPHVVDEFLTTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLU7</accession>
    <name>W6YLU7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_109496</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964191">
        <property type="protein sequence ID" value="EUC40162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693318.1">
        <property type="nucleotide sequence ID" value="XM_007695128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLU7"/>
    <dbReference type="GeneID" id="19119444"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109496"/>
    <dbReference type="eggNOG" id="KOG4157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171219_0_0_1"/>
    <dbReference type="OrthoDB" id="3681302at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="WSC" evidence="7">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC40162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="88" mass="10154" checksum="C6BAC3379CB9BCE2" modified="2014-04-16" version="1" fragment="single">YIGCYTDNDYRVLRDGYKQDNNMTRDMCAAFCKGRKYYGVQYSRECFCGDSFEIASENVPENKCNMKCTGSSLMCGGSHKMNIFEKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLZ2</accession>
    <name>W6YLZ2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">threonine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_109352</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="KI964184">
        <property type="protein sequence ID" value="EUC40232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693254.1">
        <property type="nucleotide sequence ID" value="XM_007695064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLZ2"/>
    <dbReference type="STRING" id="930090.W6YLZ2"/>
    <dbReference type="GeneID" id="19119415"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109352"/>
    <dbReference type="eggNOG" id="KOG1637">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008554_2_0_1"/>
    <dbReference type="OrthoDB" id="5423599at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070159">
        <property type="term" value="P:mitochondrial threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000039">
        <property type="entry name" value="Threonyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF50">
        <property type="entry name" value="THREONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="97"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC40232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="541" mass="61004" checksum="FEC004CCB78597B2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YM89</accession>
    <name>W6YM89_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MACPF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964171">
        <property type="protein sequence ID" value="EUC40362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693110.1">
        <property type="nucleotide sequence ID" value="XM_007694920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YM89"/>
    <dbReference type="GeneID" id="19119342"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108993"/>
    <dbReference type="eggNOG" id="ENOG502SKG1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117260_0_0_1"/>
    <dbReference type="OrthoDB" id="3231004at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="22131" checksum="F5490E0720F2B456" modified="2014-04-16" version="1">MLAPYNNSMRLGQGFNSFTQKIRMTDAVTEAKSESSSRSEDQQPKGISQIVSYSSRFVDKLSDVTDVMNVSASLSIKTGTIGGAVSGTYIDSDKFKTSDLNFFIQVKVTNQTHMAHDYTEFSKLKNLPVARFTEIYGDSFIAGWEEGGEPNALISVKILSVRTQCNTSANATPHQNASSPKNEAFNHHQNAIIARFFSGVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNY4</accession>
    <name>W6YNY4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUMO-conjugating enzyme UBC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquitin carrier protein 9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin-conjugating enzyme E2 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ubiquitin-conjugating enzyme E2-18 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_107071</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964120">
        <property type="protein sequence ID" value="EUC41092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692381.1">
        <property type="nucleotide sequence ID" value="XM_007694191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNY4"/>
    <dbReference type="STRING" id="930090.W6YNY4"/>
    <dbReference type="GeneID" id="19118974"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107071"/>
    <dbReference type="eggNOG" id="KOG0424">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_12_0_1"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="C:SUMO ligase complex"/>
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        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:SUMO conjugating enzyme activity"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000035">
        <property type="entry name" value="SUMO-conjugating enzyme ubc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="17">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="15">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00081544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC41092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="157" mass="17917" checksum="C657538D55DC07FD" modified="2014-04-16" version="1">MSLCINRLSEERKSWRRDHPFGFFAKPMRGANGMMDLKKWDCGVPGKEKTIWEGGLFKLEVTFPDEYPTKPPKCKFVPPLFHPNVYPSGTVCLSILNEEEGWKPAINIKEILLGIQSLLDEPNPESPAQADAFNLFKKDKAAYERKVRQIVKENPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQC7</accession>
    <name>W6YQC7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_31085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964236">
        <property type="protein sequence ID" value="EUC39855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693623.1">
        <property type="nucleotide sequence ID" value="XM_007695433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQC7"/>
    <dbReference type="GeneID" id="19121797"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31085"/>
    <dbReference type="eggNOG" id="ENOG502R71Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023620_5_0_1"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01299">
        <property type="entry name" value="Met_dep_hydrolase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057744">
        <property type="entry name" value="OTAase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="117"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="525" mass="58056" checksum="D67ADA1B370AA550" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQR6</accession>
    <name>W6YQR6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_110386</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964237">
        <property type="protein sequence ID" value="EUC39853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693633.1">
        <property type="nucleotide sequence ID" value="XM_007695443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQR6"/>
    <dbReference type="STRING" id="930090.W6YQR6"/>
    <dbReference type="GeneID" id="19119589"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110386"/>
    <dbReference type="eggNOG" id="KOG0769">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_6_3_1"/>
    <dbReference type="OrthoDB" id="446044at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015867">
        <property type="term" value="P:ATP transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF1">
        <property type="entry name" value="MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="10"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="119"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="212"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC39853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="36604" checksum="AC92E9E738ECD4E0" modified="2014-04-16" version="1">MGGQSKVETLPPWGNAVAGAAGAVIANTLVYPLDLIKTRLQVQVKRSPTADATNPADDEHYDSALDAIRKVFAQEGLSGLYAGMGGALLGVASTNFAYFYWYTIVRTLYMSNRALQTPPGTAVELSLGAVAGALAQLFTIPVAVVTTRQQTMSKAERKGMIATAMDVVNGEDGWTGLWRGLRASLVLVINPSITYGAYQRLREVLYPGKKNLKPMEAFLLGSLSKMLATIATQPLIVAKVGLQSKPPPSRNGKPFKSFTEVMQYIIEHEGATALFKGIGPQILKGLLVQGFLMMTKERIELSFILLFRYFRQVRAQKLQKLANLAAEKAGQAAPILVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQS1</accession>
    <name>W6YQS1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">Cytochrome c oxidase subunit 8, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytochrome c oxidase polypeptide VIII</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_105290</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cytochrome c oxidase VIIc family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964087">
        <property type="protein sequence ID" value="EUC41777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691724.1">
        <property type="nucleotide sequence ID" value="XM_007693534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQS1"/>
    <dbReference type="STRING" id="930090.W6YQS1"/>
    <dbReference type="GeneID" id="19118662"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105290"/>
    <dbReference type="eggNOG" id="ENOG502SSI3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147541_0_2_1"/>
    <dbReference type="OrthoDB" id="9974841at2759"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.49.10:FF:000001">
        <property type="entry name" value="Cytochrome c oxidase subunit 7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.49.10">
        <property type="entry name" value="Cytochrome c oxidase subunit VIIc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004202">
        <property type="entry name" value="COX7C/Cox8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036636">
        <property type="entry name" value="COX7C/Cox8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13313:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13313">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT VIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02935">
        <property type="entry name" value="COX7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81427">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00071004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC41777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="78" mass="8873" checksum="EE7CEF504AE7C05F" modified="2014-04-16" version="1">MLARATFRAVSAPTLVARRGFQSTRAQFASPYHYPEGPRSNLPFDPLKKGFAFKYWGFMATGFSLPFLLAVWQTKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRT7</accession>
    <name>W6YRT7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_41321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964174">
        <property type="protein sequence ID" value="EUC40335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693148.1">
        <property type="nucleotide sequence ID" value="XM_007694958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRT7"/>
    <dbReference type="GeneID" id="19124041"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41321"/>
    <dbReference type="HOGENOM" id="CLU_2440518_0_0_1"/>
    <dbReference type="OrthoDB" id="3687419at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="90" mass="9684" checksum="E9A934ACAAFECC73" modified="2014-04-16" version="1">MASSPSSHDINSCVLFLEGAKASALVSDVLNAALGLVRMPQSPGSLGQSSRCTRHSWVKGKMHATYPYRHLCIQCTAALSPLMSGVRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS68</accession>
    <name>W6YS68_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Cutinase</fullName>
            <ecNumber evidence="3 12">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_42991</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cutinase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="3 12"/>
    <dbReference type="EMBL" id="KI964163">
        <property type="protein sequence ID" value="EUC40470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693019.1">
        <property type="nucleotide sequence ID" value="XM_007694829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS68"/>
    <dbReference type="GeneID" id="19124192"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_42991"/>
    <dbReference type="eggNOG" id="ENOG502S47Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040058_2_2_1"/>
    <dbReference type="OrthoDB" id="2975078at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043580">
        <property type="entry name" value="CUTINASE_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF2">
        <property type="entry name" value="CUTINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00155">
        <property type="entry name" value="CUTINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 12" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="16"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="147"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC40470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="186" mass="18460" checksum="8977E02939CC333B" modified="2014-04-16" version="1" fragment="single">GLLGGSENGIVDKNCCTDMTIVFARGTGEMGNVGTVSGPPMFKAIRSKLGADRVTVQGVDYPASAAGNVNLGGDGGEKMAALVKQAKSLCPNTKVIVSGYSQGAMVVHNAFSKGLSAEDVSGAVLFGDPLKRTAVGKLPTDKVKQFCGTADQICGGGGDGGATGSHISYGSSAEAAATFAIQAAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSU6</accession>
    <name>W6YSU6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ureidoglycolate hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_30448</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-ureidoglycolate = urea + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EMBL" id="KI964148">
        <property type="protein sequence ID" value="EUC40660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692832.1">
        <property type="nucleotide sequence ID" value="XM_007694642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSU6"/>
    <dbReference type="STRING" id="930090.W6YSU6"/>
    <dbReference type="GeneID" id="19121679"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30448"/>
    <dbReference type="eggNOG" id="ENOG502S1JQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070848_0_0_1"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004848">
        <property type="term" value="F:ureidoglycolate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050385">
        <property type="term" value="F:ureidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20298">
        <property type="entry name" value="cupin_UAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="entry name" value="Ureidoglycolate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047233">
        <property type="entry name" value="UAH_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221">
        <property type="entry name" value="UREIDOGLYCOLATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221:SF1">
        <property type="entry name" value="UREIDOGLYCOLATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="34116" checksum="0C03DF8229FF267C" modified="2014-04-16" version="1">MPPSTPAPSIRIPIELLTPTAFAQFGAVIENPSTSPSAKLPIPNRVQTPEAVSANQGSATKYLDVTHMSNLYTLAPSKKPARAVMNMFVCSPRNLRPHEPSMSMPSSWGDLDLDEDEDGNDDCLKQLLDVSILERHPFTTQTFIPMGLAQQDRHTQYLVIVAPTLPASASKYRTDRAPPYPAPVMKGNGSVFDIFGRGRPSPSDEGTSTQSHFSHLHPSARPKGPGLPDLKNVRAFVATGAQAVTYGAGTWHAPMVVIGDRPIDFVVVQFANDVGNEDCQEILLKPGETATEGVVVTVDTNAAGTVQVQAGVGSVKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT58</accession>
    <name>W6YT58_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_40949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964140">
        <property type="protein sequence ID" value="EUC40780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692707.1">
        <property type="nucleotide sequence ID" value="XM_007694517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT58"/>
    <dbReference type="STRING" id="930090.W6YT58"/>
    <dbReference type="GeneID" id="19123974"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40949"/>
    <dbReference type="eggNOG" id="ENOG502SPVW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_761136_0_0_1"/>
    <dbReference type="OrthoDB" id="5362630at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="373" mass="43816" checksum="AC5771F284E81351" modified="2014-04-16" version="1">MVDSVFFRKGPSNLSPQHFLNRTVSIVEITSANQQVLAPDAPRTLQLTQIPGATLEVYVKKFDVCDGDKVDCREVDQNGKDCVYEMPPYCLAQVPDVRTNIKTYIHRERDRYLNLLLAESSSSQPMEGTESITQLTVKVALAYAEKRPESVVSMALDMWAYCRVIEREWTICGEDTLGLSKVKDPSSPWHKFIPITPIMDVQLDQIVIKDILDPLRQKLILSLEDLIKQHVPKNWFDCYLTMYILLNHIEWSCTHGNKFSKRYGMNRRYSDMRLAEAWFHTSKILLSRFHFWSNGSDPFKVNWKKPEEVKFAQLDKHQIRFMQQLQKIVKEKELHFKELRDRHYYEKDLYWTHQLFSPEWHPGLPHIVEETPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUC4</accession>
    <name>W6YUC4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Para-hydroxybenzoate--polyprenyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_28433</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964041">
        <property type="protein sequence ID" value="EUC43062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690424.1">
        <property type="nucleotide sequence ID" value="XM_007692234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUC4"/>
    <dbReference type="STRING" id="930090.W6YUC4"/>
    <dbReference type="GeneID" id="19121309"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28433"/>
    <dbReference type="eggNOG" id="KOG1381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034879_1_1_1"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="UniPathway" id="UPA00213"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate polyprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000008">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1780:FF:000001">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC43062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="30752" checksum="1D92F6D1E49D9D8D" modified="2014-04-16" version="1">MATPVAAPSAVVGTTALFFTGALVMRGAGCTINDLWDRNLDPHVERTRLRPIARRAITPLQALVFLGGQLTTGLAVLLSFPAECFWYATPSLIFVTLYPLAKRVTYYPQFVLGLTFSWGAMMGFPALGIDLLANQAALIAATCLYASNVAWTVLYDMIYAHMDIKDDVKAGIKSIALKHEKETKQVLSGLAVAQLGLLSAMGVAAGLGPIFFIGSVGGAALTLGTMIRRVKLKEVKNCWWWFVNGAWFTGGAIGLGLAGEYVAHLLGWYEDAEKKKEPGKMYVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUJ2</accession>
    <name>W6YUJ2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_29964</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964114">
        <property type="protein sequence ID" value="EUC41205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692266.1">
        <property type="nucleotide sequence ID" value="XM_007694076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUJ2"/>
    <dbReference type="GeneID" id="19121597"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29964"/>
    <dbReference type="HOGENOM" id="CLU_1414933_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="192" mass="20156" checksum="9D2124FE7A89F7B4" modified="2014-04-16" version="1">MALIHASKLPHRCSANPKPAQYCENLFCGLLHLKHARYGGTIVSSDVGLVAAHEAGSGSPGDGNAFKRVQGFVKRSLHVTKRDNSQRVTGTVSFWSTTTLAPLSAGWLKRTSRLGNYLGGSRDNTGILVYAPSEHVSCSLGNGRCRVVIVIKIGPTKAPTTTVCLDLVGSTCDDPGYGQANAATGSESSCNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUN4</accession>
    <name>W6YUN4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_29921</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964111">
        <property type="protein sequence ID" value="EUC41270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692204.1">
        <property type="nucleotide sequence ID" value="XM_007694014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUN4"/>
    <dbReference type="STRING" id="930090.W6YUN4"/>
    <dbReference type="GeneID" id="19121590"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29921"/>
    <dbReference type="eggNOG" id="KOG0393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_21_3_1"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000088">
        <property type="entry name" value="Ras-related C3 botulinum toxin substrate 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0636">Prenylation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC41270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="200" mass="22067" checksum="798974D8A4D813D6" modified="2014-04-16" version="1">MAAPATQSLKCVVTGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPISLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSIVSPPSFDNVKAKWYPEIDHHAPGVPIILVGTKLDLRDDEATKESLRQKKMAPIQYEQAVMVAKEIRAQKYLECSALTQRNLKSVFDEAIRAVLSPRAPPSAAKNKKKCTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVB7</accession>
    <name>W6YVB7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_29737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964100">
        <property type="protein sequence ID" value="EUC41488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691983.1">
        <property type="nucleotide sequence ID" value="XM_007693793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVB7"/>
    <dbReference type="GeneID" id="19121561"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29737"/>
    <dbReference type="eggNOG" id="ENOG502SIIY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF31">
        <property type="entry name" value="LAEA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="42034" checksum="7F5D83D52B128630" modified="2014-04-16" version="1">MSTRHVEAHSPPHAEAVRASSQSPAHPGAAIDSGVDVGSSSEFDQDNSAGHALVAHDDTSEASTDEGYADSDASSFLSSILSEVRRGVEIEGRLYPSYGKHAYGMPMDEKELDRNDLQHHKYTLLLRDRLFVAPVPESTFEDANCRVLDLGTGTGIWAIDMADKYPNAEILGVDIAATQPAFVPPNCIFEIDDVEEDWPYRPAHFDFIHGRDLMTAIRDWPRVIAQAYAHLKPGGWIQLASTIPGPLTDDNTIPENSGYVETARVYFEIAEKMGAPLAAPRDWNAQMKEAGFVNVQDEVYKLPMGPWPRSKRLRTVGKLEQIMILEGGFEAYMLRGYTQVLGGKVEDLQIILALAKREVRDPSIHTYVQFHITYGQKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVQ2</accession>
    <name>W6YVQ2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_105722</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964095">
        <property type="protein sequence ID" value="EUC41608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691893.1">
        <property type="nucleotide sequence ID" value="XM_007693703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVQ2"/>
    <dbReference type="STRING" id="930090.W6YVQ2"/>
    <dbReference type="GeneID" id="19118738"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105722"/>
    <dbReference type="eggNOG" id="ENOG502RVTP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_692620_0_0_1"/>
    <dbReference type="OrthoDB" id="4356994at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="15"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="400" mass="44609" checksum="D82F20A04F734C45" modified="2014-04-16" version="1">MHTDKTGRSRMNSKACDQCYRCKVKCTMELSGCGRCRLTGGVCTYSLGKWMGRPKKSSQQNSNAQARRMRDSESASLEHNHIIHVPDTRQGWELLSSSMDDSEMNTFNHETMSLFSMGDNIENKAEDCYNSPEECLSINTSEKKTSASSISPAWAQARETPTRGMETGSTQSPRESQKGTYRKHQDSTHSCLPTPQSPVYPRKFDFEMMGTDFIASPPVSMVGNIETNSTRYAEDMDCRQTHAVMQEVSTSPNEQACHCKCSQVALACLDKISVVPSEARYIDRLNIIQSALMTAERLVLCTDCPPNMTIARCCFILGNTHELVSDANSHSGDASSPTATIFSRQSIEFTRRIKRRASMLFAGLKTLQDLGSGDRRLSNMQSEFLSVLANSWLALPDYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWS5</accession>
    <name>W6YWS5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_104747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964078">
        <property type="protein sequence ID" value="EUC41973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691512.1">
        <property type="nucleotide sequence ID" value="XM_007693322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWS5"/>
    <dbReference type="STRING" id="930090.W6YWS5"/>
    <dbReference type="GeneID" id="19118564"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104747"/>
    <dbReference type="eggNOG" id="KOG0712">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1111211_0_0_1"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="8"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="250" mass="28022" checksum="DA8A1386A66686D6" modified="2014-04-16" version="1">MEPEGFEDYYATLGLQLGASPNAIRSAFHALAIKYHPDGSGISDSTLFRAAREAFDRLTNTEFRKEYDRTYWRKKLHIDPPAPSTDEQPFGNTRTYQYEAEMRERARRASPPPKKPFKKPGDPGWKYLNSAAYQKWKQLSASYYARHPECEPPVDESRPPSPGQGGLQHGLLVKMSHECVLRPCRYRSATWKVQPGGADHCVFCMEARVGCSRCPGCEALACQKCLKKIAEIEQNSCILSNKAPCATSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX85</accession>
    <name>W6YX85_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="5">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_104296</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="5"/>
    <dbReference type="EMBL" id="KI964071">
        <property type="protein sequence ID" value="EUC42150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691329.1">
        <property type="nucleotide sequence ID" value="XM_007693139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX85"/>
    <dbReference type="STRING" id="930090.W6YX85"/>
    <dbReference type="GeneID" id="19118483"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104296"/>
    <dbReference type="eggNOG" id="ENOG502SMRF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_4_2_1"/>
    <dbReference type="OrthoDB" id="5271017at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF3">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886368" description="AA9 family lytic polysaccharide monooxygenase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="7">
        <location>
            <begin position="24"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="220" mass="23394" checksum="CF25EE16BA698CEC" modified="2014-04-16" version="1">MKVSAVILAVASLASAHYTLPSINGGVPWAHVRQAKNWQDNGFVGDVTSNDIRCNQLKPGTATMTVAAGSSVKVSVNPNAYHPGPFQSYLAKVPAGADINTWDPTGAVWFRIYAEQPKFGSQLTWLAAANYDIKIPQCIAPGKYLMRNEHIAIHTAGQRGGAQFYLSCAQIEVTGGGSTSPRNLVAFPGAYSATDPGILININYPIPTSYVNPGPPTFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXH8</accession>
    <name>W6YXH8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_104001</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="KI964068">
        <property type="protein sequence ID" value="EUC42245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691245.1">
        <property type="nucleotide sequence ID" value="XM_007693055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXH8"/>
    <dbReference type="GeneID" id="19118420"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104001"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_82_4_1"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF69">
        <property type="entry name" value="HISTIDINE KINASE CONTAINING CHEY-HOMOLOGOUS RECEIVER DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="372"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="523"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="822"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="966" mass="107586" checksum="327A03D51A6CB177" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY37</accession>
    <name>W6YY37_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103336</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964059">
        <property type="protein sequence ID" value="EUC42488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690978.1">
        <property type="nucleotide sequence ID" value="XM_007692788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY37"/>
    <dbReference type="GeneID" id="19118274"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103336"/>
    <dbReference type="HOGENOM" id="CLU_2984439_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="60" mass="6504" checksum="7FA68656183F587D" modified="2014-04-16" version="1">MQFCSHGNDFSICSRAPPEMHYQSYIGIPALCAGNLPLCTSNSTTLQECCSRQTPAHVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ28</accession>
    <name>W6YZ28_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_107876</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964139">
        <property type="protein sequence ID" value="EUC40794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692696.1">
        <property type="nucleotide sequence ID" value="XM_007694506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ28"/>
    <dbReference type="GeneID" id="19119138"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107876"/>
    <dbReference type="eggNOG" id="ENOG502RR2G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007784_1_1_1"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF10">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="148"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="652" mass="73778" checksum="E72FB7B9C2F39068" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ69</accession>
    <name>W6YZ69_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mannosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_7614</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 22 family. PIGZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="KI964046">
        <property type="protein sequence ID" value="EUC42890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690590.1">
        <property type="nucleotide sequence ID" value="XM_007692400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ69"/>
    <dbReference type="STRING" id="930090.W6YZ69"/>
    <dbReference type="GeneID" id="19125334"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7614"/>
    <dbReference type="eggNOG" id="KOG4123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022957_2_0_1"/>
    <dbReference type="OrthoDB" id="10066429at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF3">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886429" description="Mannosyltransferase" evidence="12">
        <location>
            <begin position="18"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC42890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="516" mass="58890" checksum="3084949DC50A25B8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZJ4</accession>
    <name>W6YZJ4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_101994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964042">
        <property type="protein sequence ID" value="EUC43030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690479.1">
        <property type="nucleotide sequence ID" value="XM_007692289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZJ4"/>
    <dbReference type="GeneID" id="19117988"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101994"/>
    <dbReference type="HOGENOM" id="CLU_1366029_0_0_1"/>
    <dbReference type="OrthoDB" id="3685768at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="149"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="221" mass="25834" checksum="C2837B087A24FBFE" modified="2014-04-16" version="1">MPESSTNPISLVPEEYSNDWNHVQLATRYIVLRDEYLAVRTLLDGAIYARPFERERTIHNLQNMRLSLENEMQQLRTQNLQLHRACQKNRNINRELRQQYVETQETLNIVLQAQFQGDQETRAQHAKIERLQEENESLRWHMEMLVKARDEDEGSPPGLVNKGGNLQSGMDERGKTAEIPNVRVDEVKAEQEKMTKAEISGEQSCWDDNDDDDYNDDHLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZK0</accession>
    <name>W6YZK0_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688733.1">
        <property type="nucleotide sequence ID" value="XM_007690543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZK0"/>
    <dbReference type="GeneID" id="19123250"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37469"/>
    <dbReference type="HOGENOM" id="CLU_070362_0_0_1"/>
    <dbReference type="OrthoDB" id="10541236at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="228" mass="25131" checksum="FABD77E6C5A33E68" modified="2014-04-16" version="1">MSAQALNPKHQPARQPAARNWAHTGTAIGATHSHSAQRPGATTPDLPRLRRRRACDRAVLATTLAEPLEPSPELSQRAEGRIKLARRCSGARVILPCWPRGMRPPPRSSQIVGHKLPFWLRRHRLGSPRRRSLACVPKGREDPDDGGRQCRLSACILTHPAQALWNRRDSDLTKSYILADIRRADVVGSSIISSPYSCQSMVPTASLRPGSIALRPAWRCAYGIASNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZT2</accession>
    <name>W6YZT2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_38907</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690361.1">
        <property type="nucleotide sequence ID" value="XM_007692171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZT2"/>
    <dbReference type="GeneID" id="19123578"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38907"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_2_1"/>
    <dbReference type="OrthoDB" id="2213137at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF287">
        <property type="entry name" value="MFS MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="258"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC43115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="450" mass="48445" checksum="C35DC78552B1D659" modified="2014-04-16" version="1">MASTQSAQSNLTSSPHNVAPPTLDDIELFQHSDNDAPRNEASFSLPPTDGGKDAWLCLFGCFMLEAMIWGFPSCYGVFQEYYATSDEFAGQRNIAVVGACAMGIMYMDITLWFAMLKYFPRFRRYATPAGLVVVCLALGLGSLSTTVTHLIVTQGILYALGGGLAWTPILFNIEEWWVRRRGFAYGATMAGLGLSGAILPLILEWLLQSYGFRTTLRVCALSFVGLNFPIIFFFKPRLPLSQTSQSRSFDLSFWTCSNYLILQSGNVIQSLGFFLPAIYLPTFARSIGASTVQGTITIILVNAAAFVGSLCMGLATDKYHVTNCLLVSALGSAVGSFLIWGFSTSLAPLYIFCVIYGAFAGCQSSAWSAIVADTQKKRRGADSGFVWACLSAGKGVGNLCSGPLSEALMHAGNWSAGFAYGSGYGALIAFTGVTALLSGWGYAARRIGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z024</accession>
    <name>W6Z024_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_101404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690274.1">
        <property type="nucleotide sequence ID" value="XM_007692084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z024"/>
    <dbReference type="GeneID" id="19117868"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101404"/>
    <dbReference type="HOGENOM" id="CLU_2378333_0_0_1"/>
    <dbReference type="OrthoDB" id="3680457at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="92" mass="9792" checksum="D3ABE3AF87E3BEE9" modified="2014-04-16" version="1" fragment="single">TSLQAPHAASIGRSARLLGLIDGILAPVHGIRVIGHAPVKMPVLATQSQDGHVPFPYSIPNLIGCIHWESLLMAEKGPQSIAWWGKTKAPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0C4</accession>
    <name>W6Z0C4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_96396</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963990">
        <property type="protein sequence ID" value="EUC45152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688361.1">
        <property type="nucleotide sequence ID" value="XM_007690171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0C4"/>
    <dbReference type="STRING" id="930090.W6Z0C4"/>
    <dbReference type="GeneID" id="19128844"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96396"/>
    <dbReference type="eggNOG" id="KOG2386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013931_1_1_1"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14502">
        <property type="entry name" value="RNA_5'-triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000090">
        <property type="entry name" value="Dual specificity phosphatase catalytic domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF25">
        <property type="entry name" value="DUAL SPECIFICITY PHOSPHATASE CATALYTIC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="8">
        <location>
            <begin position="659"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="437"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="463"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="492"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="742" mass="81103" checksum="EB021DF921C7DF44" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1B6</accession>
    <name>W6Z1B6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_95270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687948.1">
        <property type="nucleotide sequence ID" value="XM_007689758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1B6"/>
    <dbReference type="STRING" id="930090.W6Z1B6"/>
    <dbReference type="GeneID" id="19128620"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95270"/>
    <dbReference type="eggNOG" id="KOG1199">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="OrthoDB" id="1669814at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="258" mass="26286" checksum="C281B0B485601872" modified="2014-04-16" version="1">MDTASSPHGIANNLFAITGAASGIGRATATLLIQSGAKVSLADKDEASVLQLAQELGENAVGYKVDVTKSEEVNAWIGRAGEKWGKECLDGAVNLAGISGSLAPAHAHSPSNYAAVFGVNVEGTFNCMAAELGSMRVASGDVVTGGSIVNAASITGLVGKPNCSIYCASKHAVVGLTKAAAKEQVGTGIRINAIAPGFVDTPLMHALDAELGFALPNDAVLGRRARPEEVARVIRFLLSSEASFVTGSVYQIDGGMVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z286</accession>
    <name>W6Z286_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_27489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689352.1">
        <property type="nucleotide sequence ID" value="XM_007691162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z286"/>
    <dbReference type="STRING" id="930090.W6Z286"/>
    <dbReference type="GeneID" id="19121127"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27489"/>
    <dbReference type="eggNOG" id="ENOG502SWPI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117779_0_0_1"/>
    <dbReference type="OrthoDB" id="5418867at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="153" mass="16674" checksum="37ED96848A8EB5FE" modified="2014-04-16" version="1">MPKWTPELDAIILHGVFEECNISFSKSLCIKIAERVNDAGVECTPKAIENRLYSWKKKNVSGATGLNSATSTPVQAPATPKTPRSRVKAKAEDPTTPSPSIRKRKATKLKTESAESQSEESSGLDDMLATKKKVKTEAVEEEVTLDVSAEEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2K1</accession>
    <name>W6Z2K1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_25955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687511.1">
        <property type="nucleotide sequence ID" value="XM_007689321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2K1"/>
    <dbReference type="STRING" id="930090.W6Z2K1"/>
    <dbReference type="GeneID" id="19120857"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25955"/>
    <dbReference type="eggNOG" id="KOG4178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_1_1"/>
    <dbReference type="OrthoDB" id="284184at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="33"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="300" mass="33999" checksum="7E65E34EC338B81B" modified="2014-04-16" version="1">MPELYDHDGKPVKHHLARVNGIRIHYITSGSGPPLLLLHGTPKTHYYWYRILPLLTPHFTIVAPDLRGFGATDKPPATEGYDGRTNAKDMIGIMDALEFKTFAVHGEDRGATYAFCLAGLYPNRVTHLSFCEMLLSSALTQASFFTRDNIAAQYNQTGVWNWHIPFFWLPHVPEMLIQGKEEEFWTHFMRSECCNPCALDQGAVDEWVRCAKAPGGTRGILESYRSHWVNLEIEEEILSKGKLKCKVMTVGALEFFGQRVEQQMKSVAEKGEIAEIFECGHSLAIEQPERLANLLIRLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2K3</accession>
    <name>W6Z2K3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_99500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964015">
        <property type="protein sequence ID" value="EUC43958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689536.1">
        <property type="nucleotide sequence ID" value="XM_007691346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2K3"/>
    <dbReference type="GeneID" id="19129484"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99500"/>
    <dbReference type="eggNOG" id="ENOG502R9FJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_928020_0_0_1"/>
    <dbReference type="OrthoDB" id="3678990at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="283" mass="31547" checksum="6F5E8AE47B28729A" modified="2014-04-16" version="1">MEPLHDRGRFHIPLHIPAIGDPEPIERLLDINLGEHQIISPLGRTEPPYSGNEIVSFLNMIITLRKELVCLACFKERQKRGSFRCSCTLRKRFLDRWLCVGCYVKEDHADKAMSSHIVVQDDGGGGHRHLCACGASFGAGPQPKILCNWCKGEVAGDWVDADEMEDRDAEEPDEDEQQDEEHSAADFAHMEPGELGFAKNRDESLSVYVDGTCIRGERLGRGIVRKWRLDEGLPDECICCLCEDGDANHNHNHDGNDGEANDDGDESETDENSTMAIDDGESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3U3</accession>
    <name>W6Z3U3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_103941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964067">
        <property type="protein sequence ID" value="EUC42279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691224.1">
        <property type="nucleotide sequence ID" value="XM_007693034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3U3"/>
    <dbReference type="STRING" id="930090.W6Z3U3"/>
    <dbReference type="GeneID" id="19118410"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103941"/>
    <dbReference type="eggNOG" id="ENOG502S18W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014251_1_1_1"/>
    <dbReference type="OrthoDB" id="27214at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056186">
        <property type="entry name" value="PDZ_CPAF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23658">
        <property type="entry name" value="PDZ_CPAF_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887138" evidence="2">
        <location>
            <begin position="20"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="CPAF-like PDZ" evidence="4">
        <location>
            <begin position="156"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Tail specific protease" evidence="3">
        <location>
            <begin position="359"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="766" mass="83698" checksum="0B15ED89E0BF2DE9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4G7</accession>
    <name>W6Z4G7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_97109</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963996">
        <property type="protein sequence ID" value="EUC44835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688645.1">
        <property type="nucleotide sequence ID" value="XM_007690455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4G7"/>
    <dbReference type="STRING" id="930090.W6Z4G7"/>
    <dbReference type="GeneID" id="19128987"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97109"/>
    <dbReference type="eggNOG" id="ENOG502SKUZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054797_0_0_1"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08023">
        <property type="entry name" value="GH16_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF53">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="143"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="407" mass="45498" checksum="5DC56345B6677947" modified="2014-04-16" version="1">MSGAFDKLLAKGKAKLSEFTGPSSGSHHQQGYPGQGYPGQQHQQGYPPPQGYPQAQQGYPPPNPGQYSGAQYPPQYPPQNQQWGAPPQQQQWNAPQQQQWGPPPPQQQSFGPPPIPQGSKPHTPQPGSPPPIPQNRPPSAQPPPPQNIPPPHTEKVYWRPSFDKSTPVSQNFRHEIGDHGWGNNEKQMYTDSPENSFHHDNRLIVRALVGPDKWTSARLTSHQTLSRPRGYLSATCLPPSAPGIWPAYWMLPADPFKWPTDGEVDIAESWNAETENHSCLHWGSYTGEDAQKHRVVKTSLPDLARQPHTYGFAWIEEEGIPGWRGRMIWYIDGRPVMKGSIPEGTRRMEDFRILINIAMGGTVNQGKLPAEGYYDFVVSDMKMCEEPVGGWHAFERDWGCTPEGKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4R1</accession>
    <name>W6Z4R1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="16">1.3.8.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">2-methyl branched chain acyl-CoA dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">2-methylbutyryl-coenzyme A dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="ORF">COCMIDRAFT_92070</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="31 32" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="31 32">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>(2R)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = ethylacryloyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:65296"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:156439"/>
            <dbReference type="ChEBI" id="CHEBI:156440"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:65297"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>(2S)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48256"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:88166"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:48257"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57336"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:43781"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>2-methylpropanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:44180"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57338"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62500"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="26">
            <dbReference type="Rhea" id="RHEA:44181"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24004"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:24005"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>hexanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43464"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62077"/>
            <dbReference type="ChEBI" id="CHEBI:62620"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:43465"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>valproyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-propylpent-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:65344"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:156457"/>
            <dbReference type="ChEBI" id="CHEBI:156458"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:65345"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 27">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid degradation; L-isoleucine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; mitochondrial fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 27">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.5" evidence="16"/>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686798.1">
        <property type="nucleotide sequence ID" value="XM_007688608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4R1"/>
    <dbReference type="STRING" id="930090.W6Z4R1"/>
    <dbReference type="GeneID" id="19128000"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92070"/>
    <dbReference type="eggNOG" id="KOG0139">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_0_1"/>
    <dbReference type="OrthoDB" id="10262177at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003853">
        <property type="term" value="F:short-chain 2-methyl fatty acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046395">
        <property type="term" value="P:carboxylic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01158">
        <property type="entry name" value="SCAD_SBCAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000012">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000001">
        <property type="entry name" value="Acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="Acyl-CoA_dh_N"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8 27" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7 27" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12 27" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="30">
        <location>
            <begin position="60"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="29">
        <location>
            <begin position="174"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="28">
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            <begin position="282"/>
            <end position="430"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00037895"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00039036"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00039850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00041537"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00042821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048235"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048592"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00049096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00049552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00051903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="436" mass="47602" checksum="391F987E076AD5DC" modified="2014-04-16" version="1">MASFSRSLRPLTRVATASSRSLRPAVRPAPQIRCLSMTPSRREAVDISDVPPTPITHLSETEMLMGDSVSKFANDVVLPKAREMDEAEAMDPAVVEQLFEQGLMGIEIPEEYGGSGMNFTSAIIAIEELARVDPSVSVLCDVHNTLVNTAIIKWGSEKLKKEWLPKLATNTVGSFCLSEPVSGSDAFALATKATRTENGYKINGNKMWITNSVEANFFIVFANLDPSKKYKGITAFIVEKGTPGFSIAKKEKKLGIKASSTCVLNFDDVEIPKDNLLGKEFEGYKYAIGLLNEGRIGIAAQMTGLALGAWENAAGYAWNDRKQFGQLIGEFQGMQHQLAQAWTDIQAARALVFNAARKKEAGEDFVMDAAMAKLMASQVAGRVSGQAVEWMGGMGFVREGLAEKYFRDSKIGAIYEGTSNIQLTTIAKHLQKKYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4R9</accession>
    <name>W6Z4R9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_4270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688564.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z4R9"/>
    <dbReference type="GeneID" id="19124186"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4270"/>
    <dbReference type="eggNOG" id="KOG0236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_8_1_1"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000024">
        <property type="entry name" value="Sulfate permease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
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        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
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    </dbReference>
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        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00916">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="563"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="791" mass="86695" checksum="C3181E8CE4270AAE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5A5</accession>
    <name>W6Z5A5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_5795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688511.1">
        <property type="nucleotide sequence ID" value="XM_007690321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5A5"/>
    <dbReference type="STRING" id="930090.W6Z5A5"/>
    <dbReference type="GeneID" id="19124740"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5795"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_1_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
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        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
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        <property type="entry name" value="FAD-bd"/>
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        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
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    </dbReference>
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        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
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    </dbReference>
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        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="9"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="437" mass="48607" checksum="1050EC6BD3990AE7" modified="2014-04-16" version="1">MAPAKSRPTVLIVGGGLAGLFCALECKRNGFEITVLESRPAIQTAGDFITIGPTAINALCRWPSIATALGKVAYKPDIWYHKQDGELVAGPMPPHPNFGRMISRPALHQALWHALEAENVDIRCKTKVKRYWETEDEGGVELENGDILRADMVTAADGIHTKSWTLVSRKEPEIYPSGLAMFRAAFPIERALADPTLRAKWTPTAERDKMGFFLSPTSFGIILFGQDTASWVWQHNENPETSTESWAATLSPEDALKQLDAQGHWGADLRALIATTPQNHIVDWRLMRRELKREWSSPKGRLMQIGDAAHPYLPTTVNGGTQAIEDGVSLARCLRLAIDKHGANALPAGAKVHNLLRIDRVAAIETTGMERTKKHRQVDFEQVKKNPELIRNEPAQWQIKHDPLAYAEEKFDECFASLTNGKPFINTNKPEGYVFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5H9</accession>
    <name>W6Z5H9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_102474</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964048">
        <property type="protein sequence ID" value="EUC42819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692484.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_102474"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="4188028at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
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        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="517"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
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        <location>
            <begin position="104"/>
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        </location>
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        </location>
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            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
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            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
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            <begin position="397"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
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        <location>
            <begin position="527"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
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            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
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            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="721"/>
            <end position="753"/>
        </location>
    </feature>
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        <location>
            <begin position="761"/>
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        </location>
    </feature>
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        <location>
            <begin position="805"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="824"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="854"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="892"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="916"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="936"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="973"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1079" mass="118850" checksum="E8071B2E97560BEC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5K4</accession>
    <name>W6Z5K4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_91206</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686426.1">
        <property type="nucleotide sequence ID" value="XM_007688236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5K4"/>
    <dbReference type="STRING" id="930090.W6Z5K4"/>
    <dbReference type="GeneID" id="19127833"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91206"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007230_0_0_1"/>
    <dbReference type="OrthoDB" id="5357315at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="PA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000364">
        <property type="entry name" value="Protease-associated PA domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977">
        <property type="entry name" value="TARGET OF ERK KINASE MPK-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
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    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
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        <location>
            <begin position="585"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
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            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="504"/>
            <end position="571"/>
        </location>
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        <location>
            <begin position="638"/>
            <end position="710"/>
        </location>
    </feature>
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            <begin position="151"/>
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        <location>
            <begin position="506"/>
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            <begin position="534"/>
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        </location>
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            <end position="674"/>
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        </source>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
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        <source>
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        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47047.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="747" mass="80591" checksum="B915CD7BE5C6F5B3" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6Z685</accession>
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            <fullName evidence="1">Translationally-controlled tumor protein homolog</fullName>
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        <name evidence="4" type="ORF">COCMIDRAFT_26334</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">ATCC 44560</strain>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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        <source>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC43074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z696"/>
    <dbReference type="STRING" id="930090.W6Z696"/>
    <dbReference type="GeneID" id="19121299"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28395"/>
    <dbReference type="eggNOG" id="KOG4269">
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    </dbReference>
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    <dbReference type="OrthoDB" id="185175at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF125">
        <property type="entry name" value="GTPASE ACTIVATOR (BEM2), PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04450)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="334"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="546"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="546"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="574"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="680"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="706" mass="78774" checksum="399D4810FE04D360" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6U4</accession>
    <name>W6Z6U4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_101340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
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    </dbReference>
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    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
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        <location>
            <begin position="869"/>
            <end position="1004"/>
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    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1009" mass="113574" checksum="9F7AB4593C2A1574" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z823</accession>
    <name>W6Z823_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_88977</name>
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    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
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        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="130"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="130"/>
            <end position="198"/>
        </location>
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        <location>
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            <end position="218"/>
        </location>
    </feature>
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        <location>
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            <end position="199"/>
        </location>
    </feature>
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        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC47872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="342" mass="38251" checksum="6E332717A7B1A282" modified="2014-04-16" version="1">MDSTVYSTPPTNNISLAEAIEIVEARFEDAVQSCKDDWNNGNDLVILQDNIPQLFGGILVEHFKRCVGEVSGFPVELTVMDGGNNYHTLVQMPKNMRSPQVVSSPQLAQTSPSEQTSIDLKAVAAGLKKAPRPMNCWIIFRDAMHKHLKVEFPHLTIQEISTRCSHIWHNLSPEAKKPWQDAAQSAKEEHLRQHPDYKYTPRKPGEKKKRQSRKSKRAAITATAPEVLQFQLSPNLILAVPEVTDEPTLAANPVTASGDNACPEDVSNCFDPNVFPEIYPQAPMAADFFYNAESIRHSLLDTEFNIDFNMDTTFALFDDEMLAFRDGADGDATLPSLFEDTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8F9</accession>
    <name>W6Z8F9_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_93891</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963972">
        <property type="protein sequence ID" value="EUC46078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8F9"/>
    <dbReference type="GeneID" id="19128348"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93891"/>
    <dbReference type="eggNOG" id="ENOG502SQB8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_4_1"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="31"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="356" mass="38959" checksum="B46936A51B082583" modified="2014-04-16" version="1">MSSSTAGESIAYRVIIPSVLGPVVALPLCGIRMYTKLYILRNTGHDDYAIALATILALGFSITTCYQTTNGLGKHIGDVSPYQFHQLMKIGDIAGPIFYNLSTLCIKTSLCLFYLRFSVSRGFHTVIYALLAVCVIYSSLAAFGFAWVCQPKERYWDFSITSGSCVDLDALFLANACINAATDFVLLVLPLFIIKDLTLPRRRKIGVALLLMTGSFVLVVSLIRVEAVVRGMGKIAKDGTWAMVTNFIWILVEMWMGVICTCLPTLHTFVKNRWAARCAKLVAKNNGNAMPEHQWIGLQDTPERPSSASKPVAVVNFLDSKSHGSDSSMARTIVCEEASLPPASHSNTRSTEVLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8L3</accession>
    <name>W6Z8L3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Short chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_93670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963971">
        <property type="protein sequence ID" value="EUC46133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687367.1">
        <property type="nucleotide sequence ID" value="XM_007689177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8L3"/>
    <dbReference type="STRING" id="930090.W6Z8L3"/>
    <dbReference type="GeneID" id="19128303"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93670"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_2_1"/>
    <dbReference type="OrthoDB" id="5327538at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051935">
        <property type="entry name" value="HSDL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42808">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42808:SF4">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="34327" checksum="FD235A6057C77BEE" modified="2014-04-16" version="1">MPVSTKQVALVVGASRGIGRQIAIDLAKDGYAVIVAAKSTSDASTTTPFPPDPNSPTSTISTVAREIREAGGEATPIPVDTRNYTSIESLVTTTLSTYGRLDVLIYNSGAIWWSSVAKTPMKRFQLMQRVNVEGLYGVVQACLPHFQQQDGGWRGRIVVVSPPIYSRFFRGKTAYAVGKVGMSVLTMGLAMDFQREDKTGMAVTSLWPATAIESAATKNLARDEARELRTPGIFSDAVREIVKAPVEQVNGRLLLDEDFLRERGVTEFERYSVVPGSRPRRIMPEVFPDLRVKEQDDEGKRMDSTVLRAAAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8T3</accession>
    <name>W6Z8T3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_2927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0045 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685292.1">
        <property type="nucleotide sequence ID" value="XM_007687102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8T3"/>
    <dbReference type="GeneID" id="19121475"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2927"/>
    <dbReference type="eggNOG" id="ENOG502S45I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137479_0_0_1"/>
    <dbReference type="OrthoDB" id="5587367at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029756">
        <property type="entry name" value="MTH1187/YkoF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002767">
        <property type="entry name" value="Thiamine_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051614">
        <property type="entry name" value="UPF0045_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00106">
        <property type="entry name" value="MTH1187 family thiamine-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33777">
        <property type="entry name" value="UPF0045 PROTEIN ECM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33777:SF1">
        <property type="entry name" value="UPF0045 PROTEIN ECM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01910">
        <property type="entry name" value="Thiamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89957">
        <property type="entry name" value="MTH1187/YkoF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiamine-binding protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="118" mass="12777" checksum="DA2F67BE169A8E92" modified="2014-04-16" version="1">MASSDDLSKLATPPMCTADFCLIPLGTPTASVSKEVAEVQRLLKKSGLEYSMHSAGTTLEGSWDDVMRVIGQCHAMLHQNGIVRIQSDIRVGSRTDKKQGFKDKVAAVEQLLKEDEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8Z7</accession>
    <name>W6Z8Z7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-dependent kinase 1</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_92644</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays a key role in the control of the eukaryotic cell cycle. Required for entry into S-phase and mitosis. Acts as a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II. May function in concert with npp-16 to arrest prophase blastomeres in response to anoxia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Forms a stable but non-covalent complex with a regulatory subunit and with a cyclin. Interacts with cks-1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686988.1">
        <property type="nucleotide sequence ID" value="XM_007688798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8Z7"/>
    <dbReference type="STRING" id="930090.W6Z8Z7"/>
    <dbReference type="GeneID" id="19128111"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92644"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020484_0_0_1"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
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    </dbReference>
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            <position position="35"/>
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        <ligand>
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        <source>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46510.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="715" mass="78989" checksum="AA055BF28A28EDB0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z953</accession>
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        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
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            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
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            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="203" mass="23457" checksum="DAED581291772D00" modified="2014-04-16" version="1" fragment="single">MSSNSFRENCTAVLAALSFLLLPYYITTTSKEFLLWIAISCFTNWCLKLVVNIGDAKSQERSRWKPSGVLDLLRGYPPLKANEIRILVLYPSKDRTAPLQGRFEIYDLDNGSDTSGKADQNGYEAMFNTKFPSHPMEFMVIGFKVVLIPFHLQRALLWLRHTHEERRLWIDAICVKMPERITHTQLFPQIYKRATKAIAWTGE</sequence>
</entry>
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    <accession>W6Z9J0</accession>
    <name>W6Z9J0_COCMI</name>
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        <recommendedName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_109017</name>
    </gene>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9J0"/>
    <dbReference type="STRING" id="930090.W6Z9J0"/>
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    <dbReference type="eggNOG" id="KOG4174">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF26">
        <property type="entry name" value="FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="2">
        <location>
            <begin position="86"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="396" mass="45014" checksum="052EF05BFB311A0D" modified="2014-04-16" version="1">MSKTKTKRARRELKREGERKIAAHHRKAAAKAAETKQAATKPLAKKKKQKMDSAAAKDAPPATKPAHFQPSQRKHAIPFGEYDHILLVGEGDFSFTRSLAIEHGCANVTATSYDSHEDVSSKYPTFDPISTELSSLTPPVPLFHSIDATKLSSYKHLRCKRDDNDNDNDNDGDGDQGWDTIAFMFPHTGGLSTDVNRQVRANQALLVEFFKSCIDTKDAKRRLHILQSQKREREESRKRKRGKEQGDLQEQEGGRKKKMEQNVKPFLRMGGKIIVTLFEGEPYTLWNIRDLARHVGLRVVESWKFDWEQYPGYHHVRTLGALEGGGGWKGEDREARMYVFEKIPLVADSDEEKEMERLAKVARGGRLPSQKEAMKAALQDEEKGEEKEDEDDEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9R5</accession>
    <name>W6Z9R5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_92076</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686804.1">
        <property type="nucleotide sequence ID" value="XM_007688614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9R5"/>
    <dbReference type="STRING" id="930090.W6Z9R5"/>
    <dbReference type="GeneID" id="19128004"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92076"/>
    <dbReference type="eggNOG" id="KOG2246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022549_3_1_1"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF47">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="12">
        <location>
            <begin position="177"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC46730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="473" mass="54782" checksum="03C1673925483B50" modified="2014-04-16" version="1">MPHRNLICRLLFCAIVSVSVLNIFTKASTPRLHHPAKASSHHDSSDIFCPRSPLAKDVLVVLRTGATESLEKVPVHFRTTLQCVPHYVIHSDLDEEIEGHAVHDVLKGVSDKTKQESDDFKHYHQLQKHGRRGVPQQQVMTSLSGSSQGDYMRTDNAGWQLDKWKFLPMIDQAIKEKPDAKWYVFIETDTYLGWNNLLEYLSNFDDSKPYYIGKHLYINQVEFAYGGAGFALSNPAIMKVSEQRSQHLEEYEEFTKTHWVGDCGLGKVFEDSKIPLHRAFPHFQGDSPATLNPATSKIDRDLWCYPTITYHHVSPAEIEELWEFEQDWYKRHQILLRHRDIFTELVRSKIDTSVLKWDNMSADKEYNAHDHSSAANQLERNAWKSFEHCRDLCEEQNDCMQFSFDAGSCAISTTFKLGYAKPSGRIKSGWMLDRVDDLFRQLEDRCGLRDWFAPHESASNTELKLKRMMRRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9U2</accession>
    <name>W6Z9U2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_108726</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="5">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964162">
        <property type="protein sequence ID" value="EUC40476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693002.1">
        <property type="nucleotide sequence ID" value="XM_007694812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9U2"/>
    <dbReference type="STRING" id="930090.W6Z9U2"/>
    <dbReference type="GeneID" id="19119298"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108726"/>
    <dbReference type="eggNOG" id="KOG3731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_4_0_1"/>
    <dbReference type="OrthoDB" id="96314at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005539">
        <property type="term" value="F:glycosaminoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008449">
        <property type="term" value="F:N-acetylglucosamine-6-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018958">
        <property type="term" value="P:phenol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16147">
        <property type="entry name" value="G6S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000051">
        <property type="entry name" value="Arylsulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012083">
        <property type="entry name" value="Arylsulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108:SF8">
        <property type="entry name" value="SD21168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000972">
        <property type="entry name" value="Arylsulf_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="6">
        <location>
            <begin position="8"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="5">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000972-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="547" mass="61621" checksum="83D1514E659C9687" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9X4</accession>
    <name>W6Z9X4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_86957</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48542.1"/>
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        <location>
            <begin position="461"/>
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        <source>
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        </source>
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            <dbReference type="EMBL" id="EUC48542.1"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="532" mass="55359" checksum="C7A2DBFA6F6501C8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA67</accession>
    <name>W6ZA67_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
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        <name evidence="2" type="ORF">COCMIDRAFT_91849</name>
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            <taxon>Pleosporales</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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        </source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF60">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="97"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="540" mass="60395" checksum="41C2365C2B7830E8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBM2</accession>
    <name>W6ZBM2_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_24821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC47193.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886678" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12963" checksum="D47051010976150D" modified="2014-04-16" version="1">MPLELLKSLLLLLVYLSHSWWVAVLFEARIDLQHQCGFPLLNFAPHYTHPTTISHRTRQRHPHTSVSLLSYLSEMKNPSGEMHMALQPLLHLLLSRQPLRPQSFVVPIQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCC3</accession>
    <name>W6ZCC3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_106295</name>
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    <organism evidence="2 3">
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964105">
        <property type="protein sequence ID" value="EUC41391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCC3"/>
    <dbReference type="GeneID" id="19118834"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106295"/>
    <dbReference type="HOGENOM" id="CLU_2145415_0_0_1"/>
    <dbReference type="OrthoDB" id="10399643at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="112" mass="11883" checksum="85D4F8F2CF813BD7" modified="2014-04-16" version="1">MIIVEVVAVAVAVEVAGVLAYVFAVALAPFAALLILTALDRSAHTVVVAQEVVVVVAVVVIPMTRKRERKSAPRELSQTAGSLVTLSAQRVVQLTPLHLSENAQPLVQQRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCH3</accession>
    <name>W6ZCH3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_96381</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2"/>
    <dbReference type="EMBL" id="KI963990">
        <property type="protein sequence ID" value="EUC45129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688352.1">
        <property type="nucleotide sequence ID" value="XM_007690162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCH3"/>
    <dbReference type="STRING" id="930090.W6ZCH3"/>
    <dbReference type="GeneID" id="19128843"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96381"/>
    <dbReference type="eggNOG" id="KOG1342">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007727_0_0_1"/>
    <dbReference type="OrthoDB" id="1918432at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000001">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF10">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="11">
        <location>
            <begin position="44"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="402"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="478"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="498"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="546"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="596"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="620"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC45129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="648" mass="70916" checksum="CB949288949541BB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCK7</accession>
    <name>W6ZCK7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_89879</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685942.1">
        <property type="nucleotide sequence ID" value="XM_007687752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCK7"/>
    <dbReference type="STRING" id="930090.W6ZCK7"/>
    <dbReference type="GeneID" id="19127568"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89879"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046889_1_0_1"/>
    <dbReference type="OrthoDB" id="3214149at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000201">
        <property type="entry name" value="C2H2 finger domain protein (Gli3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000031">
        <property type="entry name" value="GLI family zinc finger 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056436">
        <property type="entry name" value="Znf-C2H2_ZIC1-5/GLI1-3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23561">
        <property type="entry name" value="zf-C2H2_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="164"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="188"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="348"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="433" mass="48821" checksum="43F1594C25B4CE8A" modified="2014-04-16" version="1">MTESPSDLSEYGSDDFPEDVKGSRPRSYEATPDHDQRPNKRPRLNVRAPSSPPAPINTMPPDLDEELSEDTDGSVPASPHHHPGMSQDDDYGQEQVTVCKWDGCTAGDLHNMDKLVEHLHDDHIGTRQKKYSCEWSDCTRKGIPHASGYALRAHMRSHTREKPFYCTLPECDRSFTRSDALAKHMRTVHETEALRPSDPVPKHHSSNPTNNKQRLKLVLNNEGKKLPHDKASTPGSPSHPPNSATAVAAAASTSETDYSHNNVIYLQDLASPSAPTLVQFPPDIEFTPEELRKPANELFQLLRRQLKWATKEGEQLRAEAEELERVRREEWQAKELLLENFMEAQAATERRRRAEEGIPEDMEGWQAVEKDVAPSKALPIAPKDGKLPWWRQEGAQTHRPEVKKEEQQQQQQQPPKPADVSQQEGLQPPVPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCW3</accession>
    <name>W6ZCW3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_89714</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685889.1">
        <property type="nucleotide sequence ID" value="XM_007687699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCW3"/>
    <dbReference type="STRING" id="930090.W6ZCW3"/>
    <dbReference type="GeneID" id="19127530"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89714"/>
    <dbReference type="eggNOG" id="KOG2295">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014487_0_0_1"/>
    <dbReference type="OrthoDB" id="342064at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025239">
        <property type="entry name" value="DUF4187"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039727">
        <property type="entry name" value="SE/Ars2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007042">
        <property type="entry name" value="SERRATE/Ars2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021933">
        <property type="entry name" value="SERRATE/Ars2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165">
        <property type="entry name" value="ARSENITE-RESISTANCE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165:SF0">
        <property type="entry name" value="SERRATE RNA EFFECTOR MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04959">
        <property type="entry name" value="ARS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13821">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12066">
        <property type="entry name" value="SERRATE_Ars2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01173">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="661"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="455"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="564"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="769"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="811"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="852"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC47658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="862" mass="97784" checksum="E0C729E8F625E57E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD06</accession>
    <name>W6ZD06_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_8671</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964093">
        <property type="protein sequence ID" value="EUC41626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691835.1">
        <property type="nucleotide sequence ID" value="XM_007693645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD06"/>
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    </dbReference>
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        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41626.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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            <dbReference type="PubMed" id="23357949"/>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
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        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="49" mass="5566" checksum="CE813A300F8170DE" modified="2014-04-16" version="1" fragment="single">WHTLLPPLSMALPTFRRGTPRGELLGLNVWRSRMGKLQLAEIGRGRSHT</sequence>
</entry>
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    <name>W6ZE76_COCMI</name>
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        <recommendedName>
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            <taxon>Dothideomycetes</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FHIP family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687111.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZE76"/>
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    <dbReference type="eggNOG" id="KOG3695">
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019384">
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    </dbReference>
    <dbReference type="InterPro" id="IPR045669">
        <property type="entry name" value="FHIP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705:SF11">
        <property type="entry name" value="FHIP FAMILY PROTEIN CG3558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705">
        <property type="entry name" value="RAI16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF5917"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10257">
        <property type="entry name" value="RAI16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="567"/>
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        <location>
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            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="827"/>
            <end position="849"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00024336"/>
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    </evidence>
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        <source>
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    </evidence>
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            <dbReference type="Pfam" id="PF19314"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="891" mass="99036" checksum="FC4C3697DEDD4067" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZED0</accession>
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    <protein>
        <recommendedName>
            <fullName evidence="1">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_87516</name>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
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                <person name="Han J."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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            <strain evidence="2 3">ATCC 44560</strain>
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        </location>
    </feature>
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            <end position="548"/>
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    </feature>
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        <location>
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    </evidence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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        </location>
    </feature>
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        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46034.1"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
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    <dbReference type="NCBIfam" id="TIGR02453">
        <property type="entry name" value="TIGR02453 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CHROMOSOME 12, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
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        <name evidence="7" type="ORF">COCMIDRAFT_23476</name>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
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                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
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    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
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    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
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    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ada DNA repair protein, N-terminal domain (N-Ada 10)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="6">
        <location>
            <begin position="91"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="266" mass="29542" checksum="FC6C16579EE280B4" modified="2014-04-16" version="1">MPTYTTPTSRHRALLTRDPLSHSSFIYAVLTTHIYCRPTCPARLARRANILFFNASHEAEAAGFRACKRCKPNVAAVEDRQGQAVRRACERIEEAVGKGEEGKLRLGELSREVGFTSRYFHGVFKGRMGVTPREWVGRVVGERKRRDEEARCGVGEMGEQAWGGESFDFNDLIDFGGDAEMLNADDLTGPQDQSFTIDQELSLDANGLFQPWTGYEPAQAISGSFQTTPEVMSFGEKTMSSTSTLELDAAAMLDWDSLANMPQKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFI6</accession>
    <name>W6ZFI6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">adenosine deaminase</fullName>
            <ecNumber evidence="4">3.5.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_104043</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>adenosine + H2O + H(+) = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="4"/>
    <dbReference type="EMBL" id="KI964068">
        <property type="protein sequence ID" value="EUC42236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691240.1">
        <property type="nucleotide sequence ID" value="XM_007693050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFI6"/>
    <dbReference type="STRING" id="930090.W6ZFI6"/>
    <dbReference type="GeneID" id="19118429"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104043"/>
    <dbReference type="eggNOG" id="KOG1097">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022829_2_1_1"/>
    <dbReference type="OrthoDB" id="7202371at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006154">
        <property type="term" value="P:adenosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046103">
        <property type="term" value="P:inosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000017">
        <property type="entry name" value="Adenosine deaminase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF39">
        <property type="entry name" value="ADENOSINE DEAMINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="10">
        <location>
            <begin position="230"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC42236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="576" mass="65981" checksum="1D11A0CBF025FAA0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFI8</accession>
    <name>W6ZFI8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_86492</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684778.1">
        <property type="nucleotide sequence ID" value="XM_007686588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFI8"/>
    <dbReference type="GeneID" id="19126866"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86492"/>
    <dbReference type="HOGENOM" id="CLU_2346374_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="97" mass="10855" checksum="384D49DE811C1EA9" modified="2014-04-16" version="1">MSINPLIQNTCAPCTLDVAATSSRRLHADWLLGIKRRLAACNLYNMYSRHECCPPGPATYPATSCHILPHTPARTLYQTTQPRVKFPFSIRIPSVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHC2</accession>
    <name>W6ZHC2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">S-adenosyl-L-methionine-dependent N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_102167</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="KI964044">
        <property type="protein sequence ID" value="EUC42946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690544.1">
        <property type="nucleotide sequence ID" value="XM_007692354.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZHC2"/>
    <dbReference type="GeneID" id="19118021"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102167"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_6_3_1"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041068">
        <property type="entry name" value="HTH_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF21">
        <property type="entry name" value="NON-REDUCING POLYKETIDE SYNTHASE AUSA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18558">
        <property type="entry name" value="HTH_51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="9">
        <location>
            <begin position="218"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="10">
        <location>
            <begin position="1112"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="1469"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="1589"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1112"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1258"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1421"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1567"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1665"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1433"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1572"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="6">
        <location>
            <position position="1142"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="6">
        <location>
            <position position="1322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC42946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2066" mass="226311" checksum="F95627176138840C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHG3</accession>
    <name>W6ZHG3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TAFII28-like protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_23011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF11 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684069.1">
        <property type="nucleotide sequence ID" value="XM_007685879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHG3"/>
    <dbReference type="STRING" id="930090.W6ZHG3"/>
    <dbReference type="GeneID" id="19120362"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23011"/>
    <dbReference type="eggNOG" id="KOG3219">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035243_1_0_1"/>
    <dbReference type="OrthoDB" id="28335at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08048">
        <property type="entry name" value="HFD_TAF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045127">
        <property type="entry name" value="TAF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006809">
        <property type="entry name" value="TAFII28_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04719">
        <property type="entry name" value="TAFII28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII28-like protein" evidence="7">
        <location>
            <begin position="141"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="329" mass="36225" checksum="00628928D2C63F3D" modified="2014-04-16" version="1">MSSNRKRGSISSHSGAPAKKRKPSNLRNAFSPDAESIGGSPRQYSRSPSVESNITTSVINGVGGSKKRRKKGGDGGSVAGSSVRGGKGGDGRSAVGGEDEGEEEDDDEDEMGEEMGMEIEGGMSVEARRKQEKEYERMLEDFMTPAQMDRYATYRRIRLKRETVRKLVNQTLSQSVPQPIIIAVTSYSKTFIGELIDRALTVRDEWSAVRTHLPNPDLPGPILSQSLGRPSAHIKDERNKPTNTDIQSAGWYLNQVDRTQSIWKEVDKNASLQERLRACDKGPLTPAHLREALRRYKRDRDGGGAGFAGMSLEGVERTMGRTGGKRLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHQ4</accession>
    <name>W6ZHQ4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carbohydrate-binding module family 18 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_33155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
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            <strain evidence="2 3">ATCC 44560</strain>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="11449" checksum="F8CC0B95F10E8B26" modified="2014-04-16" version="1">MHFQYALSQLFAVMALASPSPEANSHPALSNRDSLPLDKRACSYNGCACVSGLAAGIYCGNCVVGAGTYAIRTKRVSTHAYQCNSSGGCCDYGVASDCGKSGARCQQGSPN</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">ATCC 44560</strain>
        </source>
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        <subcellularLocation>
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        </subcellularLocation>
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    </dbReference>
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        <property type="entry name" value="THOC7"/>
        <property type="match status" value="1"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
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            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC49585.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="349" mass="38823" checksum="ACF2C43878E5AB23" modified="2014-04-16" version="1">MATKEWGLLSQADEDALHNVSRLLAVEARPYTNAAGRLLKPGFFEDARPKQLLSPPPDATAAEEEAAALKVEREQQAHNIEIWRKDIMNELSLLDYAILRAEFTTNSNHTERERYAVEKTAIEAKQDHVRKTIEDLRVRLVEAKETLAVRKTYDELTEKITSSKMLKPRDEQAHAHVKLDQEIRELEHEVQSAKDTWSERRTQFGRIEEEAREMLRMIKDEKEEAERKEGMMKDGDEDGEGEGSMSRGDVSHAGTPRPDGGMTPVHASQGGEGSSLRAPPQDRLKPLSRDVSVAPSARSGAAEDTEMADLGTNSGHANADDSDGLEEGEDLEDGEHDGDDGPSMSMDES</sequence>
</entry>
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    <accession>W6ZI53</accession>
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        <name evidence="2" type="ORF">COCMIDRAFT_101565</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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            <end position="311"/>
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            <end position="92"/>
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        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="311" mass="34205" checksum="EF81D036317D6B87" modified="2014-04-16" version="1">MEPSREPPWAEHEKVYLLAEVLKAAQVPSHVLFAFIRDSNIQPRWNDMALPPGRSVRSSQMAFDTLAATYSVPGQDYRRPHLPAPMMYPGPEVPKKRPHQPETSTPVGRLLQPRPPHSYPGEYIPAGPAYPSAVHPQGEPTHKKKRGRPTKAEAQQRAQEAAARGEVYPPPRRGRQSLTGPPEQSPLGPDPRPLDRTTPPTTSSSQAPPVQTPQQQTGVEQGSESSSEKRKRARPQPLELEKLHTPTGMGSPLTYGSGDLGRNQAYSAFTPNSAPLPSSTETRDRDVRMEGVEETQARTTTPHSFKDTVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIF1</accession>
    <name>W6ZIF1_COCMI</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">COCMIDRAFT_101189</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <location>
            <begin position="35"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="205" mass="22798" checksum="07DE75406078D0EE" modified="2014-04-16" version="1">MLLFSAPPCDSLLPRGPAKQTISKRLALPFWSTTPASIPLLPRTPQKKASRPQPPPRRGKQSALQTKPTQMSPHADSPRSSTFAPTLGSIPEVFEYDPLDARHRPASLNDVPETPDAFLPEASIASPPALTRATSWPAIIQAPSRRVASSLAVSKALRRILEADRARRRRIMKAYLKAIVFLKYLWHANERYGHVMATTGMYMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIL0</accession>
    <name>W6ZIL0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_45079</name>
    </gene>
    <organism evidence="10 11">
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small Tim family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686257.1">
        <property type="nucleotide sequence ID" value="XM_007688067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIL0"/>
    <dbReference type="STRING" id="930090.W6ZIL0"/>
    <dbReference type="GeneID" id="19124264"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_45079"/>
    <dbReference type="eggNOG" id="KOG3489">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141397_1_0_1"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="85" mass="9750" checksum="620B74D23935AF9A" modified="2014-04-16" version="1" fragment="single">SGLGNLDLTKLSDRDKQELQQFAMNEGQKARIQSSIHSLTDTCFRKCIPTGTVKFGKLDRYEEPCMRQCVDRFLDANLVVLRELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIP1</accession>
    <name>W6ZIP1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_3817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686230.1">
        <property type="nucleotide sequence ID" value="XM_007688040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIP1"/>
    <dbReference type="STRING" id="930090.W6ZIP1"/>
    <dbReference type="GeneID" id="19123416"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3817"/>
    <dbReference type="eggNOG" id="ENOG502SR0E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066899_0_0_1"/>
    <dbReference type="OrthoDB" id="1638493at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="41495" checksum="93825C1DF4B9BE05" modified="2014-04-16" version="1">MLFEDLATELVVQVFLSCTSVTDVTALSSTCKRFRNIYSSSQKLTILESAAEAQFGPLHDLTQLLTHNASQPAHIFRSAPFSLALLTQIVAYGRVAEKWCDIYPFKKWKHNFENRRLLTPQERFKLRRAIYRIWLYSRAFHNPAHPRELRATRLVLLKRAALLHNWTTCDLAEISDIHNIMREVVQSNICPSNGTIARKFKKRHPGNEGGLLFNIHLNYPPSAPQAFNPFFTTTTTTTTTPNPLSTHFNNTTTYTSRFAATKYSLSPSHEVGAEGWGDDIPHYYVVQDYLKLDPAQILYLKENAPLKGMVEGYVRSLWCEYEWFTNNGETWVQTLEFVLDERGEDVGGFMEAIVEGELGVCCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIS7</accession>
    <name>W6ZIS7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_83246</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683544.1">
        <property type="nucleotide sequence ID" value="XM_007685354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIS7"/>
    <dbReference type="GeneID" id="19126217"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83246"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_0_0_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF9">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890053" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="21"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="61"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="491" mass="52733" checksum="F7DCE71FC8073346" modified="2014-04-16" version="1">MKPLASLAFVTFTLAQHALAVTSQQIHTDLAKTLSSGSEVVLTTDPSYATSFTQRWTVYSKAEPAYEVAVKPATATDVQKIIQYATKNNVPFLATGGGHGYSTSLSGVKGALNIDLSKFKKVAVDASANTMTVGAATIFADMLDPLYAAGKQMPSGGSSTPSIIGVTLGGGIGPLTGAYGLLIDSLLSVEMVTGSGQILTVSATKNSDLFWGMRGAGVNFGIVTSATYRIYDTINNGMVYNADMSFNGEKNESIFKILRTYQGTQDNKLALSVSSSVKNKVPEISLSAIYFGTKEQGDAAIKVFLDQQPIFSNISVVPYNKLVYVANFGGDAFARIKGVRADMWGYQLNDVTVSTLSSTYTKFVNFVLDNPALESSASWLIEKFGLGVTATIPDDSTAYPWRKAVAYGFFAFYLPENVSEQLTNTADQFAEKIRSDLASGCGNPQGNVFPNYARGTETPEQVYGKSKLPKLRSLKKKYDPKGLFNKYNSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJS8</accession>
    <name>W6ZJS8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein COX16, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cytochrome c oxidase assembly protein cox16, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_82336</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COX16 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683199.1">
        <property type="nucleotide sequence ID" value="XM_007685009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJS8"/>
    <dbReference type="STRING" id="930090.W6ZJS8"/>
    <dbReference type="GeneID" id="19126029"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82336"/>
    <dbReference type="eggNOG" id="ENOG502S9GT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131611_2_0_1"/>
    <dbReference type="OrthoDB" id="5516033at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020164">
        <property type="entry name" value="Cyt_c_Oxase_assmbl_COX16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17130:SF14">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17130">
        <property type="entry name" value="MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14138">
        <property type="entry name" value="COX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC50305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="116" mass="13513" checksum="41A8E9655E7F6953" modified="2014-04-16" version="1">MPGPFTSKSFSATLPNSLAARYRKSLQKHPFLLFGLPFLTTMVAGSFMLTPATALRYERYDRKNQQITQEQAMGLRGERRKVNMRDEYYRLQAKDLEDWEQRRVKRLPGEPDGTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK48</accession>
    <name>W6ZK48_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_38157</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964015">
        <property type="protein sequence ID" value="EUC43961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689522.1">
        <property type="nucleotide sequence ID" value="XM_007691332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK48"/>
    <dbReference type="GeneID" id="19123412"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38157"/>
    <dbReference type="eggNOG" id="ENOG502TKB6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035432_0_0_1"/>
    <dbReference type="OrthoDB" id="3683755at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886943" evidence="3">
        <location>
            <begin position="36"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="593"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="570"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="632" mass="71964" checksum="A466A6AD7492B35C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKB8</accession>
    <name>W6ZKB8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytoene desaturase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phytoene desaturase (3,4-didehydrolycopene-forming)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_88940</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685633.1">
        <property type="nucleotide sequence ID" value="XM_007687443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKB8"/>
    <dbReference type="STRING" id="930090.W6ZKB8"/>
    <dbReference type="GeneID" id="19127379"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88940"/>
    <dbReference type="eggNOG" id="KOG4254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019722_2_1_1"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016166">
        <property type="term" value="F:phytoene dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000171">
        <property type="entry name" value="zeta-carotene-forming phytoene desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008150">
        <property type="entry name" value="Phytoene_DH_bac_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734:SF1">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00982">
        <property type="entry name" value="PHYTOENE_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="550"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="586" mass="65457" checksum="1072F584D70E5AD5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLE3</accession>
    <name>W6ZLE3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_37760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689078.1">
        <property type="nucleotide sequence ID" value="XM_007690888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLE3"/>
    <dbReference type="GeneID" id="19123317"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37760"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_16_5_1"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="20"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="339" mass="35596" checksum="38C477BC56FFE1E1" modified="2014-04-16" version="1">MAATHRAALLSSPGKPLEITDADTLHAGLGEVLIRNHAVALQPLDAKILIAGYGPAAHLAYPAVLGTSGAGIIEAVGEQVQGLAVGDRVVFDTKAYVDTNNNQRTGAWQQLVACDAKTVAKIGDVAFEQAVLVDFPLQTAAAALHVFLGMGKPGSGAKDGKVLIWGAGGAVGSYAVQFAKQAGYTVVVTASPRDVERQMKLGASEVVNYKDTDAVAKLRSLGQYKYLFTASGDAASQSALASLLESTGGSFASVLPSAVELPSKVSLIYAAFSQAAQKEEYSEWRDWWYQQYLPKVLSGGLVEPVRFTKVQGGLSALQQASQDVFDSKAKGKLVIDPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLF4</accession>
    <name>W6ZLF4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_87557</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685188.1">
        <property type="nucleotide sequence ID" value="XM_007686998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLF4"/>
    <dbReference type="STRING" id="930090.W6ZLF4"/>
    <dbReference type="GeneID" id="19127091"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87557"/>
    <dbReference type="eggNOG" id="KOG1311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034009_0_0_1"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF23">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="13">
        <location>
            <begin position="146"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="278"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC48364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="409" mass="46416" checksum="C2C8B57038BCB196" modified="2014-04-16" version="1">MAPPPLPPAVTDPPKPGAITNPAVEQKIGQATSVIIPLLEFGAVGFATWVFVYLICIKYLINPSDQIQRDFDIQPRRSTGIALIVVYAILLLFLTITWLRLLQMIWSRPDIVPFGNTAQEKEHASTRDFAFDQYDAFICDYQGLPLWCDKCHNWKPDRTHHCKELGRCVRKMDHYCPWAGGIIGESTHKFFMQLVAYAALYTTFTWIVVAIFLAERISKMGSRPGTWIGALAVGVLFSVFSFTMSCMTGWNLMINYTSVEGIQRGGIHNIAFLISQPSRRSSTTMPPGTPPSPSGKTHKKKPDRTTEGERIEEDWPVLTTVIRASKRSYVVMQTKPFEHPWYTTLMQGWKDTMGDGILDWLLPFKQSPCKNRSHRGEFAWGEVVYDMARAYEEKHPEARLALLHGSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM88</accession>
    <name>W6ZM88_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_80179</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682474.1">
        <property type="nucleotide sequence ID" value="XM_007684284.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZM88"/>
    <dbReference type="GeneID" id="19125619"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80179"/>
    <dbReference type="eggNOG" id="ENOG502QQFV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001029_0_0_1"/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="Lowry S."/>
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                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="89" mass="9455" checksum="CFDD64506A570528" modified="2014-04-16" version="1">MFRGAGKLRWPGVAFCEAGTASPPRHARTPQHVYKAYPPAIHGSHQSRARDAWRRSSHAAAAFKLCGSLQGVFGNISVTAAAGTLIPCL</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wang R."/>
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                <person name="Copeland A."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="168"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="187" mass="20762" checksum="50E37744870AF43B" modified="2014-04-16" version="1">MARLGGIACCWLLAAGRLPACWDRPRTTRKRPVGGQGTTLTLPARPTAATGFFPYHHCHVHMYVRACTRAKQDTHPCPRLRTRLGLPVGMHIPYSTVALLYPAHIRIPSDIPPTERPSACLAWWLGSSCTAPRELGRGLVLVLVLVLVQWQCHDRCFRPPGLVAPARPFFSPHPPPSDPNTPAFRMR</sequence>
</entry>
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    <name>W6ZQ41_COCMI</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="Lowry S."/>
                <person name="LaButti K."/>
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                <person name="Lindquist E."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="314" mass="34483" checksum="A1F6EF8D98C5CCC1" modified="2014-04-16" version="1">MRAPAPALDGMGDILKSAISHTAETPISSFDSRNLSSFPSSVDDDSDPSDSLLVLAPLYIPESGNDEAAAQERPGFTTKRYNPDESSRTWRDWLITLFAGRKPTLSSHNHHKRTDSFIYNSAGTQSASQPLKPSKKQDATTAPTQKPALKHTAPCNHAPRLLLSTVIPSVCTPKSHLVTHCLSYTKISPAPLTAYTGYAVVARDDYPPERVIRGFDVPDRPALTAPSSRRNNTAANLLDRDRDAWPSWNRNITSPADLPFGKTHPGRVWISRQAGMNSRGKTGKCGGDWSNCQDASRCSSIGVEEWPFSQYCYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZT46</accession>
    <name>W6ZT46_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bax inhibitor family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_832</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682818.1">
        <property type="nucleotide sequence ID" value="XM_007684628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZT46"/>
    <dbReference type="STRING" id="930090.W6ZT46"/>
    <dbReference type="GeneID" id="19126207"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_832"/>
    <dbReference type="eggNOG" id="KOG1630">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046868_1_0_1"/>
    <dbReference type="OrthoDB" id="1277691at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF112">
        <property type="entry name" value="GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="37387" checksum="F835ED056B170B83" modified="2014-04-16" version="1">MASLLRRPFAITATLRQATHSSPQSLSIRAFHNTPLKQHPHFFRPAKPTVSSSQNVSRFQQAFRRSYQQAAYNPLAQGDLRQRLLYGAGIFGATLLGINLIFNRETREDGGMPPFEREYLNDTFLHTGLGVGMIGIAARALHMNGWSFRLMSANPWLVLGVGLVGSIGTMYGTMATHPSNYVQKYALWTAFNGTQALLLSPLFFMHPAILARAGLYTAGMMGSLAFVGATAKTDKYMYLGGPLLAGVAIVALSGLAPMVVPATAARTLMFTENIWLYGGLAVFGGFTLYDVQKVLNHARMAERGLIPKDPVNEAISLELDFINIFIRMVQILGMQQNRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTG5</accession>
    <name>W6ZTG5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_81156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682780.1">
        <property type="nucleotide sequence ID" value="XM_007684590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTG5"/>
    <dbReference type="GeneID" id="19125814"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81156"/>
    <dbReference type="HOGENOM" id="CLU_3049992_0_0_1"/>
    <dbReference type="OrthoDB" id="10580890at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="54" mass="5994" checksum="C72E02B231B7B344" modified="2014-04-16" version="1">MSDTVNQISTHHVLALPHKPTNATGYWDFALPQCSNAFHLRISIVGVCARQCDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU01</accession>
    <name>W6ZU01_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">UEV domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_31586</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682338.1">
        <property type="nucleotide sequence ID" value="XM_007684148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZU01"/>
    <dbReference type="STRING" id="930090.W6ZU01"/>
    <dbReference type="GeneID" id="19121901"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31586"/>
    <dbReference type="eggNOG" id="KOG2391">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017548_2_1_1"/>
    <dbReference type="OrthoDB" id="306304at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072666">
        <property type="term" value="P:establishment of protein localization to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11685">
        <property type="entry name" value="UEV_TSG101-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052070">
        <property type="entry name" value="ESCRT-I_UEV_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017916">
        <property type="entry name" value="SB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008883">
        <property type="entry name" value="UEV_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306:SF3">
        <property type="entry name" value="TUMOR SUPPRESSOR PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306">
        <property type="entry name" value="TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05743">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09454">
        <property type="entry name" value="Vps23_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51312">
        <property type="entry name" value="SB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51322">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="UEV" evidence="10">
        <location>
            <begin position="8"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="SB" evidence="9">
        <location>
            <begin position="505"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="148"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="280"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="347"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC51019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="63438" checksum="FBABB8AFF372FAA2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU34</accession>
    <name>W6ZU34_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC51059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZU34"/>
    <dbReference type="GeneID" id="19121243"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_281"/>
    <dbReference type="eggNOG" id="ENOG502SS9D">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_500548_0_0_1"/>
    <dbReference type="OrthoDB" id="6079484at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="544" mass="60629" checksum="83F7BC3B54159DC1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUP0</accession>
    <name>W6ZUP0_COCMI</name>
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        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
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        <name evidence="9" type="ORF">COCMIDRAFT_79724</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUP0"/>
    <dbReference type="GeneID" id="19125532"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79724"/>
    <dbReference type="eggNOG" id="ENOG502S025">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_2_1"/>
    <dbReference type="OrthoDB" id="5278984at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF131">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="51"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="300"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC51264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="343" mass="38267" checksum="89168AF8077C02BB" modified="2014-04-16" version="1">MSSPLGNGTSLFGGYQFDISQFNFEDHSSNIPLVRIPCILMIVLVLLTVALRIVARLKYIHKIFFDDVLIIFATLFTVALATACIVATTHGLGQHIWILPLLEILEKLKSIILDLYICQILYACAIALTKLAIISSYFRFVPDQRFHMWMYITMFPVVGLWITGVFVTFFQCLPYYGAWDFMIERKCIDYIAYLYASSAVNALTDLALCVLPLPYFWRLDMSRKQRIILCMLLGGGVSACIVGIVRIGLLHSLHALDITYKSVPCLILSVSECSLGIISVSIPAIRPLARQFFPAAMRGVSSPSSRARTRQIRLSSIPPSGDRVPMDADDKQKASASYGSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX59</accession>
    <name>W6ZX59_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C-CAP/cofactor C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_87384</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCC family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685067.1">
        <property type="nucleotide sequence ID" value="XM_007686877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX59"/>
    <dbReference type="STRING" id="930090.W6ZX59"/>
    <dbReference type="GeneID" id="19127049"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87384"/>
    <dbReference type="eggNOG" id="KOG2512">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032612_1_0_1"/>
    <dbReference type="OrthoDB" id="194775at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1250">
        <property type="entry name" value="Tubulin Binding Cofactor C, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027684">
        <property type="entry name" value="TBCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031925">
        <property type="entry name" value="TBCC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038397">
        <property type="entry name" value="TBCC_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139">
        <property type="entry name" value="TUBULIN FOLDING COFACTOR C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16752">
        <property type="entry name" value="TBCC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="7">
        <location>
            <begin position="137"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC48431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="313" mass="34961" checksum="156705A56DD22D84" modified="2014-04-16" version="1">MFETNLKETFYRKFQDDVASLEAQISSLPDTPAASRERNEAIEQCLAGIDRLSHDVMDASSYLPAYDQRTYSEAIKSLSEKLQSIRNAFDPPKKFSFKNKRKEATAPSSTPTPAKEQPSTSIPPPSQQQDDTPSDLTHKSSTRITLASTPSTTNSPTVSHLANCIVNLTTSPTPFATLYLRNIKNSLILCGHVAGPIHITHVTNSVIVTLCRQFRMHDSKNVDIYLHSASRPIFEDCEGLRFAPLPGCYITPQISESPNLWDQIDDFKWLKAEPSPHFSIIPEDKRIPDDVWTNIVPEEKVVPLQDVLTAVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZXJ9</accession>
    <name>W6ZXJ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thymidylate synthase</fullName>
            <ecNumber evidence="2">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_86670</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="2"/>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684853.1">
        <property type="nucleotide sequence ID" value="XM_007686663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZXJ9"/>
    <dbReference type="STRING" id="930090.W6ZXJ9"/>
    <dbReference type="GeneID" id="19126908"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86670"/>
    <dbReference type="eggNOG" id="KOG0673">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021669_0_2_1"/>
    <dbReference type="OrthoDB" id="766at2759"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.572.10:FF:000013">
        <property type="entry name" value="Thymidylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548:SF2">
        <property type="entry name" value="THYMIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="THYMIDYLATE SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate synthase/dCMP hydroxymethylase" evidence="9">
        <location>
            <begin position="35"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="341" mass="38187" checksum="879B30852F9C0774" modified="2014-04-16" version="1">MTATTIDPETRPQTQKDTETQNPPPPPSNPAHEEHQYLSLIRDILQNGEHRPDRTGTGTYAIPFPAQMKFALSRPSADPTQPPTLILPLLTTKRVFLRAVIGELLWFIAGSTHSKPLSDAGIKIWDGNGSRAYLDSVGLSHYEEGELGPVYGFQWRHFGADYKGHAHDYTGEGVDQLAEIIDKLKNKPYDRRIILSAWNPADIKKMALPPCHMFAQFYVSFPGHKQGEERPRGVLHSLLYQRSCDMGLGVPFNIASYALLTHMLAHVCDLTPGTFTHTMGDAHVYLDHVEALKVQIEREPRDFPELRIKKEVGGSIDGWVESEFEVVGYKPHASLAMKMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZXL5</accession>
    <name>W6ZXL5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide lyase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_23598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684817.1">
        <property type="nucleotide sequence ID" value="XM_007686627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZXL5"/>
    <dbReference type="GeneID" id="19120468"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23598"/>
    <dbReference type="eggNOG" id="ENOG502QW7I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016764_1_0_1"/>
    <dbReference type="OrthoDB" id="302705at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052063">
        <property type="entry name" value="Polysaccharide_Lyase_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42970">
        <property type="entry name" value="PECTATE LYASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42970:SF1">
        <property type="entry name" value="PECTATE LYASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887178" evidence="3">
        <location>
            <begin position="17"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="402" mass="42178" checksum="EBF05990D8EE6D30" modified="2014-04-16" version="1">MHFLVLLPLLATSASALAFPGAEGFGRNAVGGRGGSVYVVTNLDDAGAGSLRDAVSKPDRIVVFSVGGLITITDRMVVSKRVSILGQTAPGAGITVYGNGWSFSNADDAIVRYIRIRMGKKGASGKDAITIAEGHNMIFDHVSVSWGRNETFSISGSEVGNITVQNSIIAEGLETHSCGGLMQTALGNGISLFRNLYIDNKTRNPKVKGTNDFTNNVVYNWGNGGGYIAGDSSERSEANIVGNYFISGPSTTVPAFTRGNDLFDGFVQGNFVDSGKDGVLNGKELGVTKENYGGMNIKGTKFAYPAPAKILSASDALALAEKGAGASKVRDSVDQRLVAELKSYGKLGQLISDENAAPMNGPGTIDGGKKWVDVNGNGIPDDVESQFKNVEDWANSLVPSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZXM6</accession>
    <name>W6ZXM6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PWI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_86919</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684866.1">
        <property type="nucleotide sequence ID" value="XM_007686676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZXM6"/>
    <dbReference type="STRING" id="930090.W6ZXM6"/>
    <dbReference type="GeneID" id="19126952"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86919"/>
    <dbReference type="eggNOG" id="KOG2253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009938_0_0_1"/>
    <dbReference type="OrthoDB" id="6275295at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12446">
        <property type="entry name" value="RRM_RBM25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052768">
        <property type="entry name" value="RBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034268">
        <property type="entry name" value="RBM25_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806">
        <property type="entry name" value="RBM25 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806:SF4">
        <property type="entry name" value="RNA-BINDING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="108"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="PWI" evidence="5">
        <location>
            <begin position="631"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="302"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="504"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="302"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="333"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="504"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="723" mass="80509" checksum="529029D2BC833B29" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZU5</accession>
    <name>W6ZZU5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_85020</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684219.1">
        <property type="nucleotide sequence ID" value="XM_007686029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZU5"/>
    <dbReference type="GeneID" id="19126584"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85020"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF237">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ATNE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="544" mass="62150" checksum="07C78EF6332BD3B9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1N1</accession>
    <name>W7A1N1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinetochore protein Mis13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_22493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Martin J."/>
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                <person name="Grimwood J."/>
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                <person name="Xue C."/>
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                <person name="Salamov A."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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        </source>
    </evidence>
    <sequence length="503" mass="57631" checksum="1219A566E5158E95" modified="2014-04-16" version="1">MAQSPLIVILAGAAVSYFLYTRIALYLARRRFKKEHNCQPCKAQFHKDPILGLDVMKAMAKYSKEHITLQETKKRYERLGNTYHNRIVNQPYIMTCEPENIKAVLSLRFKDYSFAHRQPAFGPLLGHGIFNADGDRWANSRHLLRPNFARDQVADIDAFERHFNLMLKHIPKDGSTVDLQDLFFHLTLDTATEFLFNHSTDSLRMLGQEDAENEDTIFGKAFNFAQEDVTVRARYGPLDRFRRNVEGKRAIEICHTYIEKFVDDALQFRQNLDAEKAAGGDKYYFIQEVAKQTTDKKRIREELINILLAGRDTTASLLSNMFFAISKNPEIYAKLREEVATLEGRTPTYSELKNLKYVKWCLNESLRIHPVVPGNSRYATRDTVLPLGGGPDGRSPLFVLKGTTVGYSPYTMHRRQDIYGPDADEFKPERWETLRPGWEYLPFNGGPRICLGQQYALIEASYVTVRLVQEFKAIESRDPGPWQEGLTLTLCSLNGVKVGLTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPE5</accession>
    <name>W6YPE5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_111281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964344">
        <property type="protein sequence ID" value="EUC39540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693942.1">
        <property type="nucleotide sequence ID" value="XM_007695752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPE5"/>
    <dbReference type="GeneID" id="19119745"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111281"/>
    <dbReference type="HOGENOM" id="CLU_2782668_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="69" mass="7247" checksum="98B1F4A97E179529" modified="2014-04-16" version="1" fragment="single">NPPTSTGHKSTTMATIDKAFAAIASQGLEGESAYFAAIENFGVEVSTLTRRHHAQHDSCTTASFVAHIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQC0</accession>
    <name>W6YQC0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Swiss Army Knife RNA repair protein HAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_110433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964239">
        <property type="protein sequence ID" value="EUC39835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693642.1">
        <property type="nucleotide sequence ID" value="XM_007695452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQC0"/>
    <dbReference type="GeneID" id="19119596"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110433"/>
    <dbReference type="eggNOG" id="ENOG502S30I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022771_0_1_1"/>
    <dbReference type="OrthoDB" id="5596992at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018812">
        <property type="entry name" value="SAK_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF23">
        <property type="entry name" value="OB FOLD-CONTAINING PROTEIN, NUCLEIC ACID BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10307">
        <property type="entry name" value="HAD_SAK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Swiss Army Knife RNA repair protein HAD" evidence="2">
        <location>
            <begin position="56"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="536" mass="59781" checksum="78A9FEE78F799617" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQH4</accession>
    <name>W6YQH4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964224">
        <property type="protein sequence ID" value="EUC39910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693571.1">
        <property type="nucleotide sequence ID" value="XM_007695381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQH4"/>
    <dbReference type="GeneID" id="19119559"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110180"/>
    <dbReference type="eggNOG" id="ENOG502RA2B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084522_1_0_1"/>
    <dbReference type="OrthoDB" id="2446447at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02219">
        <property type="entry name" value="cupin_YjlB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047121">
        <property type="entry name" value="YjiB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448">
        <property type="entry name" value="BLR7373 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448:SF2">
        <property type="entry name" value="CUPIN TYPE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-1" evidence="1">
        <location>
            <begin position="59"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="185" mass="20634" checksum="AA16B1EC093D1E1B" modified="2014-04-16" version="1">MSVVWPEQYTLPGSTYVPNSILPVLIYRNVLPTPINSELTKNICEGNDWEKRGEWGEIRIPHFHPNTHECYVIIRGSSCLALGRAEEDEGTDGVEIDIRMGDVIVIPAGVSHRSLRSEGGFRYIGLYPKDAPRWRNNHCKGEGSMRALAEEIKNVPVPDSDPVFGVNGPLSKIWKSKLAGDRAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR33</accession>
    <name>W6YR33_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_41614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964214">
        <property type="protein sequence ID" value="EUC39973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693503.1">
        <property type="nucleotide sequence ID" value="XM_007695313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR33"/>
    <dbReference type="GeneID" id="19124098"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41614"/>
    <dbReference type="eggNOG" id="ENOG502R9WA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2687644_0_0_1"/>
    <dbReference type="OrthoDB" id="3693032at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="74" mass="8197" checksum="0D84199F37956065" modified="2014-04-16" version="1">MVKAGFEGTPSNYSLSYNNNCSYNDLSDNNNYKEYIKILVIKLSNLKSNYNMLVEVAKVVGGTVKITGKKADVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR44</accession>
    <name>W6YR44_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_9959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964198">
        <property type="protein sequence ID" value="EUC40105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693383.1">
        <property type="nucleotide sequence ID" value="XM_007695193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR44"/>
    <dbReference type="GeneID" id="19129496"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9959"/>
    <dbReference type="HOGENOM" id="CLU_721879_0_0_1"/>
    <dbReference type="OrthoDB" id="3694092at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="425" mass="48965" checksum="40A5A2D879CB9B02" modified="2014-04-16" version="1">MSTPDLGLYVPTDDPLYSTRDKVITRSHVIGRMLVQDILQYGFIPPNFRITRRMPSGAADTLGHRVYYTDVLSSTVLTAHPLSPNGARVHPKLAKEFVDTREDIVSLFQPPVPQYQAGNFKFQVHDDWESALAASLASFGRENITKDVVTDVCQTIKDDSWPVYHDLYHPSDRDTAVFQNEPECAAVAEWFKRSLVILCPYTPADGTGWDRIYGEKNRPPVRFRWSTGPQALRKMTFLVCIPAWGESVTKKAHWLTLEPTDAYAATWDNLHKSRNLIELSDDWKFPQSLHSVYWKFAWVLVAAHRTVVHDRLPKDHDLGNWIYQYGQHMLKCKNDRKLSPFNYKPNQAYSGPKVGFQELGCWIFRNNVCLRYVKLWEAADEAHMKYLMDRTDAHWSDYKAKNAKLCEILEVEDDGMETTDSTDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRJ7</accession>
    <name>W6YRJ7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964074">
        <property type="protein sequence ID" value="EUC42077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691409.1">
        <property type="nucleotide sequence ID" value="XM_007693219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRJ7"/>
    <dbReference type="GeneID" id="19123760"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39838"/>
    <dbReference type="HOGENOM" id="CLU_114186_0_0_1"/>
    <dbReference type="OrthoDB" id="10284980at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="127" mass="14076" checksum="7BE69177E5B15F6B" modified="2014-04-16" version="1">MGTGAESPGLSCPLDVDLFPAYSDDSPLCDCSFAHLLLALIVRRDQVLMGIGFPWGATSRTCRCRCLCMESTWIRLRLCACSATICLGWTLSCLYSVLIRWHSRFVHVPLAVAFALYATALFYSIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSK2</accession>
    <name>W6YSK2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_9548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964152">
        <property type="protein sequence ID" value="EUC40600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692878.1">
        <property type="nucleotide sequence ID" value="XM_007694688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSK2"/>
    <dbReference type="STRING" id="930090.W6YSK2"/>
    <dbReference type="GeneID" id="19128664"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9548"/>
    <dbReference type="HOGENOM" id="CLU_2222768_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="106" mass="12066" checksum="739EF6C79C020924" modified="2014-04-16" version="1">MARSATLKFSDMREEKFHLIIGCTGKRPNWAILKDLPPDAISEKTSQIVVRQISKFFHQISEGALIFPSLHSEMWQFMEARVWLVPDGCKPVWTQFCSRKTGAGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSL7</accession>
    <name>W6YSL7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Opi1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_7973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964061">
        <property type="protein sequence ID" value="EUC42437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691026.1">
        <property type="nucleotide sequence ID" value="XM_007692836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSL7"/>
    <dbReference type="STRING" id="930090.W6YSL7"/>
    <dbReference type="GeneID" id="19125533"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7973"/>
    <dbReference type="eggNOG" id="ENOG502RG16">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015714_2_0_1"/>
    <dbReference type="OrthoDB" id="2441642at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013927">
        <property type="entry name" value="TF_Opi1_Ccg-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR OPI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38406:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR OPI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08618">
        <property type="entry name" value="Opi1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="537"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="368"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="574" mass="62488" checksum="B3530286269574CB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTL0</accession>
    <name>W6YTL0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_107556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964131">
        <property type="protein sequence ID" value="EUC40925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692570.1">
        <property type="nucleotide sequence ID" value="XM_007694380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTL0"/>
    <dbReference type="GeneID" id="19119071"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107556"/>
    <dbReference type="eggNOG" id="ENOG502S8ZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131085_0_0_1"/>
    <dbReference type="OrthoDB" id="5418749at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42030">
        <property type="entry name" value="DRBM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42030:SF1">
        <property type="entry name" value="DRBM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11756" checksum="5CD14CD96AE8A273" modified="2014-04-16" version="1">MTSPDSWSQRLREHCLVRGIPEPIYTDLSDRRGGRTAWTTMVSVSGTEYQARFWYDGDYLSQAKEDCSEVALRTITGYMNSAQTPPPASHYRSLGTQMNQSITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUS1</accession>
    <name>W6YUS1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_8953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964109">
        <property type="protein sequence ID" value="EUC41308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692159.1">
        <property type="nucleotide sequence ID" value="XM_007693969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUS1"/>
    <dbReference type="GeneID" id="19127496"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8953"/>
    <dbReference type="HOGENOM" id="CLU_670860_0_0_1"/>
    <dbReference type="OrthoDB" id="3800724at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="42559" checksum="27A4AA7E80682464" modified="2014-04-16" version="1">MDSLSEEILDHIISEVVKPLPDRHGACYADLVSISMVSRKFHRITEPYLYRSIVLSEKNKDQFLKTIRCCSELSQYPRELCIKPSCNITHETLRLAPQLPGLHKLDLDLTSCKTSDLLPVLGLPSVTALCLSGVVARQIDDASLIDWEIANTAITSLEMSFSDPETWWEDCDEIWKFAAVFRNLKSLSIHSDYEGERKHTLNGPVFRCLVHAFRHAFETSLRSFSFKCNDVNHDYIYQGDVAVSGTFDAREILKQSQLKSLEIDTMCLHRSSQEEKLRSQELGPSCLPASLRTLYLRHLVATGNLNPIERNLMHSDEAQCLSQLVNLGARRARFPNLEKMTLAISLPPFFEEVASRIVRVQARKVKLKLELILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW96</accession>
    <name>W6YW96_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_105193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964085">
        <property type="protein sequence ID" value="EUC41803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691670.1">
        <property type="nucleotide sequence ID" value="XM_007693480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW96"/>
    <dbReference type="GeneID" id="19118644"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105193"/>
    <dbReference type="eggNOG" id="ENOG502T0SW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_870344_0_0_1"/>
    <dbReference type="OrthoDB" id="5372935at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="302" mass="34932" checksum="36C75A7EAA609826" modified="2014-04-16" version="1">MTRGPFKLFDLPRELRDKIYYQYLYRPGRVYYTAHDRPFWETYGKSDDFSNLFTVSKQVYHEAFNVFCEANTIALSVQYNPREDYSKPLTGLLRLFPERAAASLTRVSHTYRDIITRAVGKWGYAPSHGSIAQGGDGTGHYQKHNSAGETFVEILRDAEILRQFFPKLIVFEAGWFPEPPFHEYPEQLGPVRKIARLWKEGVEEGKIRDIWLDTMQGWLQGKSVVPLSCIQFSLNGYAADGFGDDLDVLFNEAYIALVKERTTEDDIEDSGRAWLEAMDKEKTTRKKTNRKKQGRKTREESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWY2</accession>
    <name>W6YWY2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">T-complex protein 1 subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_8347</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964076">
        <property type="protein sequence ID" value="EUC42028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691453.1">
        <property type="nucleotide sequence ID" value="XM_007693263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWY2"/>
    <dbReference type="STRING" id="930090.W6YWY2"/>
    <dbReference type="GeneID" id="19126263"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8347"/>
    <dbReference type="eggNOG" id="KOG0358">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_9_1_1"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03338">
        <property type="entry name" value="TCP1_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000010">
        <property type="entry name" value="T-complex protein 1 subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012717">
        <property type="entry name" value="Chap_CCT_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02342">
        <property type="entry name" value="chap_CCT_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC42028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="533" mass="57290" checksum="79D4F959A4EDDF74" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYL5</accession>
    <name>W6YYL5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methylmalonate-semialdehyde dehydrogenase (CoA acylating)</fullName>
            <ecNumber evidence="2">1.2.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_6227</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.27" evidence="2"/>
    <dbReference type="EMBL" id="KI964004">
        <property type="protein sequence ID" value="EUC44437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689012.1">
        <property type="nucleotide sequence ID" value="XM_007690822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYL5"/>
    <dbReference type="STRING" id="930090.W6YYL5"/>
    <dbReference type="GeneID" id="19124886"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6227"/>
    <dbReference type="eggNOG" id="KOG2449">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_10_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000002">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase (Acylating)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000003">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase [acylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866:SF3">
        <property type="entry name" value="METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="54"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="543" mass="58498" checksum="31536934A255A865" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ64</accession>
    <name>W6YZ64_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA repair protein RAD14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_7609</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964046">
        <property type="protein sequence ID" value="EUC42885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690587.1">
        <property type="nucleotide sequence ID" value="XM_007692397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ64"/>
    <dbReference type="STRING" id="930090.W6YZ64"/>
    <dbReference type="GeneID" id="19125330"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7609"/>
    <dbReference type="eggNOG" id="KOG4017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053731_0_1_1"/>
    <dbReference type="OrthoDB" id="5368863at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000715">
        <property type="term" value="P:nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21077">
        <property type="entry name" value="DBD_Rad14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.530.10:FF:000003">
        <property type="entry name" value="Dna repair rad14 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.530.10">
        <property type="entry name" value="XPA C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000465">
        <property type="entry name" value="XPA/RAD14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022656">
        <property type="entry name" value="XPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037129">
        <property type="entry name" value="XPA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00598">
        <property type="entry name" value="rad14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05181">
        <property type="entry name" value="XPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="XPA C-terminal" evidence="12">
        <location>
            <begin position="251"/>
            <end position="301"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00072989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05181"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="409" mass="46817" checksum="1C43BBD22AF5CB4E" modified="2014-04-16" version="1">MSGRQATPPRVTRSAGKLPPNPPTPEQIRRMEEARLKSKAAAQQAQSSSAPKTGEKRAYSSITTSQTPSTVRNAAAASPQKRDQNGFIQPPSNDYIQPAKKYARSDFIEYDFSKMTDTKGGFLSTTDDPHNKAMWKGQPKEEQKPEGMTITEWERERIRRKLRANRAGPYEPGISILNTVNGKEEDEEAALLEAAENAEIESGTFKGKYGDGKRDIKGKCRECSSLEIDWKWQDTFSISVCNSCKEKFPDKYSLLTKTEARDDYLLTDPELKDEDLLPHLERPNPHKQFFHPMQLFLRLQVEAYAFSPQKWGSPEALDAEYAKRQVISKERKQKKFQNKLEDLKKRTRVEAYKRARLAGDSDGVQFGQRIKGRFDRHEHEWGRSVLDPETGMTRKRCEECGMDVEELEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZT6</accession>
    <name>W6YZT6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_68821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963996">
        <property type="protein sequence ID" value="EUC44857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690466.1"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502SNJZ">
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886985" evidence="2">
        <location>
            <begin position="19"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="422" mass="46488" checksum="26A2CF842790157F" modified="2014-04-16" version="1" fragment="single">MAARYAFVAFASATIASAQSTTDDPYYDPIYSSSYSSAAFWTVTARYAEQVTEIPYTYDYSDVMTDTYTATRTIKDDAIPTASPYLVTTSRDWYDTDVQIVASYYTTGVVAESDLVAETTYDYDSTATTTSTSVTTSTRYSMQVTMTAPASCPTPFTITTTASVSIPTRVTAHISPSSIETGTATDSYGSIVYKYETWYLTAGAAPFQTSSDYYYEYYIASCSTPPPSRSTSSSSGSGSGSGSGGSSSYYDDCYYCGSYLKNYIIAIAVIIPSLFLLGFLESWMWFRRLMMGRSAMRFGTICWVLISLWILCFTRMQDRRSKEDQKLLAEKWRNMGSGAAFKAWWKWGFRHKYPEELLGQFSKTTVGIVPPGQPLHPEISQTPPVGGPAAPGQVFYYGPPPPGWVQGPNGAFVPPQGYVYPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z021</accession>
    <name>W6Z021_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_5820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z021"/>
    <dbReference type="STRING" id="930090.W6Z021"/>
    <dbReference type="GeneID" id="19124748"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5820"/>
    <dbReference type="eggNOG" id="KOG4197">
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    </dbReference>
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    <dbReference type="OrthoDB" id="1908178at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050667">
        <property type="entry name" value="PPR-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939">
        <property type="entry name" value="MEMBRANE-ASSOCIATED SALT-INDUCIBLE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939:SF1">
        <property type="entry name" value="OS04G0684500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="361"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="599" mass="68835" checksum="89A539438A1C8D5A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0H6</accession>
    <name>W6Z0H6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_38851</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964037">
        <property type="protein sequence ID" value="EUC43178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690299.1">
        <property type="nucleotide sequence ID" value="XM_007692109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0H6"/>
    <dbReference type="STRING" id="930090.W6Z0H6"/>
    <dbReference type="GeneID" id="19123566"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38851"/>
    <dbReference type="eggNOG" id="KOG0756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_329319_0_0_1"/>
    <dbReference type="OrthoDB" id="10253709at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005371">
        <property type="term" value="F:tricarboxylate secondary active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015742">
        <property type="term" value="P:alpha-ketoglutarate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006843">
        <property type="term" value="P:mitochondrial citrate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000078">
        <property type="entry name" value="Mitochondrial DNA replication protein YHM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014839">
        <property type="entry name" value="Crt10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053017">
        <property type="entry name" value="Mito_Cit/Oxoglu_Carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982">
        <property type="entry name" value="CITRATE/OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982:SF1">
        <property type="entry name" value="CITRATE_OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08728">
        <property type="entry name" value="CRT10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="23"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="119"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="216"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="627"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="631"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="859" mass="94425" checksum="320B5EF51B3B9899" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0U5</accession>
    <name>W6Z0U5_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_100510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC43580.1"/>
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    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="288590at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="178"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="329" mass="37007" checksum="DAD9306424E3E7A4" modified="2014-04-16" version="1">MVNMNLRTLDFTKFTGTDQERKEFCQAFLDGITEVGFVKLINHDLDDKTNSELFQQSRNLFTLPREGKEEFANVIGPKPQRGWSCIGAETTATLNTPGVINMVRVNNEASLQEHFDMGPVDDPEFPNVYPSEEKAPGFKNWMEQYFIKSQHLSLQLMEALEIALDLPKSALVDRCEGHASEIRMIYYPETNVKELADGKSKRIWPHTDFGILTLLAQGSTGGLQIEDKNNPGGYVSVPLVEKTELLINVGDTLERWSNGRIPAGLHQVAASGETEDGTLPERYSVAFFLKANRKTSAGPIPIFVPKGTKSKYEEMTALEYHRRRTAIMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0Z0</accession>
    <name>W6Z0Z0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial export protein Som1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_106442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964108">
        <property type="protein sequence ID" value="EUC41334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692150.1">
        <property type="nucleotide sequence ID" value="XM_007693960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0Z0"/>
    <dbReference type="GeneID" id="19118863"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106442"/>
    <dbReference type="eggNOG" id="ENOG502SG5C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142986_2_0_1"/>
    <dbReference type="OrthoDB" id="3983163at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024645">
        <property type="entry name" value="Mitochondr_Som1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11093">
        <property type="entry name" value="Mitochondr_Som1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10189" checksum="830CE7DA832F2E72" modified="2014-04-16" version="1">MAPPVSAIPVSELETQLNTLPSGRARNPPIALSECALKELVQYKCNVQPSEKRGGVPSVVCEPVVRMLRRCQGGLSVETTAWEGWKLKQEGVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1E3</accession>
    <name>W6Z1E3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_100579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964026">
        <property type="protein sequence ID" value="EUC43528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689949.1">
        <property type="nucleotide sequence ID" value="XM_007691759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1E3"/>
    <dbReference type="STRING" id="930090.W6Z1E3"/>
    <dbReference type="GeneID" id="19117700"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100579"/>
    <dbReference type="eggNOG" id="ENOG502S47U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064532_0_0_1"/>
    <dbReference type="OrthoDB" id="4159154at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051285">
        <property type="term" value="C:cell cortex of cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052413">
        <property type="entry name" value="SUR7_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019">
        <property type="entry name" value="CELL MEMBRANE PROTEIN YLR413W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019:SF7">
        <property type="entry name" value="SUR7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886359" evidence="2">
        <location>
            <begin position="20"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="299" mass="32559" checksum="1F000A2C3DA45454" modified="2014-04-16" version="1">MRFLALLPVLCCTAALILSFLCLFAGHKKGFMEDYSLLTLNTSAIGQNLVDRASNSDSTISNIINLIPDSITDTVTDEINERIDALRERAGIEDWYSAHMLNYCEGQYTPGEVANATLKQDDISKNVTECSKNKAMYKFNPTDIIQRALNRSGIDITLQDLQWPDDIQNGIDALNAVMAAMFVLYVIAICLIFLTLVASLVGILTSGRLSACLNIGLSLLAFLAVGIASGLVTAVMIKGTDVINEHGNQIGLESHYGGKFLALTWAATGLMLLAVLAWFAALCFGRSERRSRTPRKSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1I3</accession>
    <name>W6Z1I3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(His) guanylyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA-histidine guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_105995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964099">
        <property type="protein sequence ID" value="EUC41514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691976.1">
        <property type="nucleotide sequence ID" value="XM_007693786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1I3"/>
    <dbReference type="GeneID" id="19118781"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105995"/>
    <dbReference type="eggNOG" id="KOG2721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044271_3_1_1"/>
    <dbReference type="OrthoDB" id="5959761at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008193">
        <property type="term" value="F:tRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024956">
        <property type="entry name" value="tRNAHis_GuaTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007537">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038469">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729:SF1">
        <property type="entry name" value="TRNAHIS GUANYLYLTRANSFERASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04446">
        <property type="entry name" value="Thg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNAHis guanylyltransferase catalytic" evidence="4">
        <location>
            <begin position="17"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00032480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="272" mass="31080" checksum="7F9717A21F4D0DB2" modified="2014-04-16" version="1">MDPQPSDDASQPPSLASRMRSYEASTDHILPTNQPIILRLDGHGFSRFTSRFSRPFDERIHNAMINTSSDLLHFFPQATLAYTQSDEITLVFPSGVQTFNERVQKLCSLSASYCSVRFNRHLELALQEMPNPPVKGDMEHVLGTAHFDARFFPVPSVQEALNNIIWRCRNDAVRNAVSSFARTLYTPSELHGKKTNELIDLMLKDKGVKYDEAVPKWAIEGCLIKREQYEHQGVNAKTGQVEKTFRTRPRVEQRGLTIFDEAGLKLITHKYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1M1</accession>
    <name>W6Z1M1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_27942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964024">
        <property type="protein sequence ID" value="EUC43613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689870.1">
        <property type="nucleotide sequence ID" value="XM_007691680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1M1"/>
    <dbReference type="GeneID" id="19121210"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27942"/>
    <dbReference type="HOGENOM" id="CLU_1844735_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="139" mass="15426" checksum="339347A8931FBD0E" modified="2014-04-16" version="1">MGVVRRQLWGSWVGIDDVRNTLANSRADGRYRSRLERSAILWVVIQDAGDPTTAIMLRPADVLVVIDDTPATGYKTAPSPDKVGLELHPIPRHVCVEQRCNALVGDCWKAFGSEGLWTKLHTRYNGCMDPSRQSENGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1S1</accession>
    <name>W6Z1S1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689545.1">
        <property type="nucleotide sequence ID" value="XM_007691355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1S1"/>
    <dbReference type="GeneID" id="19125044"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6693"/>
    <dbReference type="eggNOG" id="ENOG502SM3Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070881_0_0_1"/>
    <dbReference type="OrthoDB" id="537467at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="343" mass="37972" checksum="277AA6D456D17280" modified="2014-04-16" version="1">MSWMDSWSRPSKHAVTPPPLYLTVGDSVPYCHSCGRVIGDRRKTQKAAEVKYCSARCRNSKPGPIDRKIEATFAALLNGASIESLKEGAGAEPASDGVKTDRNEEDHEHGKGRKGEKKHKKKPSKTTKGDHRVIVECSTVEEIVFQREKDPEKVYGRRKNRKARFVVEKPEDWRSVDMIDHPAPGTASSSTETSTQPPPPDLTSDEDTMSDSEGEAEGGIVLDPSSPPGTTSHALPDTIEYGYGSGKIRPPQAQNDVNGSVGGEKGWAERIEETDEMKLKRREGQRKADEREMVRKAARRGCAFGFTVPDEPEKRKCEAVMKGAVVEASFAKGEWGVRWRERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1V3</accession>
    <name>W6Z1V3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964022">
        <property type="protein sequence ID" value="EUC43673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689800.1">
        <property type="nucleotide sequence ID" value="XM_007691610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1V3"/>
    <dbReference type="GeneID" id="19123457"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38404"/>
    <dbReference type="eggNOG" id="ENOG502T68R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1454145_0_0_1"/>
    <dbReference type="OrthoDB" id="3650120at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887085" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19261" checksum="22A1D877DC327AC3" modified="2014-04-16" version="1">MFNSFIICSFAYASLAFAASIPQHKVQQPLLPDHQAGGLKPNNIHVMLAFIESGGNMQKLAEIPLNTRIVAAAVNPPQEPLTLRLGLNIPNRLSAIKIAMAVTVEDRSISLERLDKIMCRITPKTDAKEKEAMKGEGKPDELPWFMLRDGTVELEDSSSQWFLGGRAIQSFECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z273</accession>
    <name>W6Z273_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_99935</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964019">
        <property type="protein sequence ID" value="EUC43803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689709.1">
        <property type="nucleotide sequence ID" value="XM_007691519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z273"/>
    <dbReference type="GeneID" id="19129569"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99935"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_12_0_1"/>
    <dbReference type="OrthoDB" id="2962696at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="230"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC43803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="294" mass="31343" checksum="394C58F909044002" modified="2014-04-16" version="1">MPAKASTDDLHVAKLFSVKGYVCVVTGGGSGIGLMAAQALAANGAKVYITGRRQEALETAAKSHNPDEGGQIIPLSPCDVTKKDDLERMYQELASKEKYINLLVASAGVSGEKAIPDAEKATDMKKKLFDNETFEGWADTYTTDVTAVYFSTVVLLPLLQAGTETHGHLSASVIVISSMSGIIKDAQGHFSYNAAKGGTVHLSKLMSAEFQKLRIRVNSIAPGYFPSEMTAKESDEQQKSDLPDEKIQEKGHVPHGRAGSDAEMAQAVIFFTKNSYVNGQILAVDGGVLNVVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2L6</accession>
    <name>W6Z2L6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_98978</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964010">
        <property type="protein sequence ID" value="EUC44175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689336.1">
        <property type="nucleotide sequence ID" value="XM_007691146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2L6"/>
    <dbReference type="GeneID" id="19129372"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98978"/>
    <dbReference type="eggNOG" id="KOG0502">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_23_1"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="3">
        <location>
            <begin position="206"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="697"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="726"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="759"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="797" mass="90586" checksum="E19B8D852F02604D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2M6</accession>
    <name>W6Z2M6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_99372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964014">
        <property type="protein sequence ID" value="EUC43983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689491.1">
        <property type="nucleotide sequence ID" value="XM_007691301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2M6"/>
    <dbReference type="STRING" id="930090.W6Z2M6"/>
    <dbReference type="GeneID" id="19129459"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99372"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006696_1_0_1"/>
    <dbReference type="OrthoDB" id="635774at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
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                <person name="Bushley K.E."/>
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Han J."/>
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    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="48"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="136" mass="14260" checksum="B5D627CCC1B64508" modified="2014-04-16" version="1">MSERGAFRGRGGGRGGDRGARGGGRGGGGGGGGGGAHAGGQTERPKKENILDLSKYMDKQITVKFSGGREVIGTLKGYDQLMNLVLDEVKEALTDEDGNIRYRKLGLIVARGTLLVVISPVDGSEEIANPFLQEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z392</accession>
    <name>W6Z392_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_98133</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964004">
        <property type="protein sequence ID" value="EUC44430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689041.1">
        <property type="nucleotide sequence ID" value="XM_007690851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z392"/>
    <dbReference type="GeneID" id="19129196"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98133"/>
    <dbReference type="eggNOG" id="KOG1289">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004495_0_3_1"/>
    <dbReference type="OrthoDB" id="4476201at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF29">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="562" mass="59966" checksum="ECD673D7792B1901" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4N0</accession>
    <name>W6Z4N0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein YTM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">YTM1</name>
        <name evidence="11" type="ORF">COCMIDRAFT_37498</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR12/YTM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688791.1">
        <property type="nucleotide sequence ID" value="XM_007690601.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z4N0"/>
    <dbReference type="GeneID" id="19123258"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37498"/>
    <dbReference type="eggNOG" id="KOG0313">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2163">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006571_0_0_1"/>
    <dbReference type="OrthoDB" id="534815at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03029">
        <property type="entry name" value="WDR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012972">
        <property type="entry name" value="NLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028599">
        <property type="entry name" value="WDR12/Ytm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08154">
        <property type="entry name" value="NLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
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        </location>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC44678.1"/>
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    </evidence>
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        </source>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
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                <person name="Salamov A."/>
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                <person name="Han J."/>
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                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="273"/>
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        </location>
    </feature>
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        <location>
            <begin position="354"/>
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        </location>
    </feature>
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        <location>
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    </feature>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00382"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45050.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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    </evidence>
    <sequence length="796" mass="86076" checksum="955E8FE83CE97426" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z573</accession>
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        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
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    </protein>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:intracellular signal transduction"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="entry name" value="BcCMK3, calcium/calmodulin-dependent protein kinase"/>
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    </dbReference>
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        <property type="entry name" value="Calcium/calmodulin dependent protein kinase"/>
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    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
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        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SERINE THREONINE PROTEIN KINASE"/>
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    </dbReference>
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        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
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    </dbReference>
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    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="91"/>
            <end position="387"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
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        <location>
            <begin position="461"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="515"/>
            <end position="547"/>
        </location>
    </feature>
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        <location>
            <begin position="560"/>
            <end position="588"/>
        </location>
    </feature>
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            <begin position="731"/>
            <end position="773"/>
        </location>
    </feature>
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        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
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        <location>
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            <end position="483"/>
        </location>
    </feature>
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        <location>
            <begin position="530"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
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        <location>
            <begin position="731"/>
            <end position="749"/>
        </location>
    </feature>
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        <location>
            <begin position="755"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="773" mass="86819" checksum="6D877AFC1D559298" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5X7</accession>
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            <fullName evidence="4">FAD-binding domain-containing protein</fullName>
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        <name evidence="5" type="ORF">COCMIDRAFT_96279</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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            <begin position="13"/>
            <end position="382"/>
        </location>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="610" mass="67907" checksum="AF24701198A3A82F" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6Z6A2</accession>
    <name>W6Z6A2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_101801</name>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="88" mass="9725" checksum="41397AB1A8DE554F" modified="2014-04-16" version="1" fragment="single">RILPMTQMHIYVLVQHVLLPSIFSLYLVAPCSIRQSSTTLGNGSCSCFDSTLTLVPSPDRSGVWFRPTHVHPALQMTCCVHIGSIEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6H1</accession>
    <name>W6Z6H1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxyvinyl-carboxyphosphonate phosphorylmutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="KI963981">
        <property type="protein sequence ID" value="EUC45585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687894.1">
        <property type="nucleotide sequence ID" value="XM_007689704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6H1"/>
    <dbReference type="STRING" id="930090.W6Z6H1"/>
    <dbReference type="GeneID" id="19128585"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95101"/>
    <dbReference type="eggNOG" id="KOG1260">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027389_3_0_1"/>
    <dbReference type="OrthoDB" id="1923844at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42905:SF2">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13714">
        <property type="entry name" value="PEP_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32222" checksum="7BE3D685F0F75F3F" modified="2014-04-16" version="1">MAAVEKLRAMLADPEKFIACPGVYDGLTARIALQEGVDCLYMTGAGTTMSRLGVADMGIATFNDMLANASMLASLSPRTPLIADADTGYGGPVMVGRTVSAYIRAGVAGLHLEDQIVNKRCGHLSGKQLVSIDEFEARIRAARLARDESGGDIVIIARTDALQSFGYDEALRRLRAAVAQGAEVAFLEGVTTAEDARRICVDMAPTPCLFNNVPGGVSPDFGVKQCREMGYKLAIFPLLACEVVYPAVRKAVQQMKELGSVKSVEEDGRRYGPRELFRLCGMDELIDFDVKAGGLGYKNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z703</accession>
    <name>W6Z703_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fms interacting protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_5082</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963978">
        <property type="protein sequence ID" value="EUC45750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687711.1">
        <property type="nucleotide sequence ID" value="XM_007689521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z703"/>
    <dbReference type="STRING" id="930090.W6Z703"/>
    <dbReference type="GeneID" id="19124494"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5082"/>
    <dbReference type="eggNOG" id="KOG2216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082754_0_0_1"/>
    <dbReference type="OrthoDB" id="20582at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019163">
        <property type="entry name" value="THO_Thoc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375">
        <property type="entry name" value="FMS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375:SF3">
        <property type="entry name" value="THO COMPLEX SUBUNIT 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09766">
        <property type="entry name" value="FmiP_Thoc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="27918" checksum="8CBC7A9E6930EBDC" modified="2014-04-16" version="1">MTDQQVSHPEPGEAMPADLSTVNMADLVKTPHNARLYQEVQNLKKLINELVDFQLAHPKSSKAESREDLDNEKKAMREIEKREKYIRAQLSVIKTLYRQSVLKVREEKAKTSDDRAVNDALILGLHNLKYEEQSLRSEISAAENYDHKYMKLPLIPLEQFLEEFPEHKESTEHDLMTARIEHEHQVRLKLEERRQEKLKQKQKLIAEVKKGKDDLTKLDTMVEKFIEAAEPIKKVLSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7H8</accession>
    <name>W6Z7H8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_89656</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685892.1">
        <property type="nucleotide sequence ID" value="XM_007687702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7H8"/>
    <dbReference type="STRING" id="930090.W6Z7H8"/>
    <dbReference type="GeneID" id="19127517"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89656"/>
    <dbReference type="eggNOG" id="KOG0236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_8_1_1"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000024">
        <property type="entry name" value="Sulfate permease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="580"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="617"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="762"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="622"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="778"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="840" mass="92089" checksum="D9CC98F8CDB68AFE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7X4</accession>
    <name>W6Z7X4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Defect at low temperature protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLT1</name>
        <name evidence="9" type="ORF">COCMIDRAFT_5010</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Required for growth under high-pressure and low-temperature conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DLT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687611.1">
        <property type="nucleotide sequence ID" value="XM_007689421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7X4"/>
    <dbReference type="GeneID" id="19124465"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5010"/>
    <dbReference type="eggNOG" id="ENOG502RAJJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022833_1_0_1"/>
    <dbReference type="OrthoDB" id="4096362at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038869">
        <property type="entry name" value="DLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021:SF1">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="116"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="317"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="460" mass="50623" checksum="BFA90471B425A727" modified="2014-04-16" version="1">MRIPLFRIWYSTTYTAILIILLVFLAVTPADTIYQSIKSNEIQKLFVIGGVYVLTSLIVLLIYSTRIYTNRTVLAAIPKSYVPVEEGEVGKGVRRMIVKHFKRSAVVAWDSRPRDLRGEVEDEDEEKGQLSRAGTAESKKDKEKSHKKKGHHHHAPDATIIPVSPKSPPWGHISHPGWASPSSPDLPNLQYWSVICELPNLIEAKAVSLAPPDPALEESAQQYPDNAPPLPDARIVTLLQRPRAMGLREYLSRLAEFGLLNPPSLGPAFLAQYEYARFSTTSLTETQFRDLMAIFAEVLNGMTEVDPVVIEEARALDVESDTRSLAPTESSMDSTISSHSHMPYRTPQLDRKSTLSSLNSFLSTSSSDASTPHSPQTVRTAPSRQHERGSTIYGTPSQRSLAGSESETGSVVIHARSRRSPSTILPNSSESSLGSAGSVIRLNLNPSEGELPYQYNIDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7X6</accession>
    <name>W6Z7X6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_42307</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the Golgi-associated retrograde protein (GARP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS51 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964022">
        <property type="protein sequence ID" value="EUC43659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689804.1">
        <property type="nucleotide sequence ID" value="XM_007691614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7X6"/>
    <dbReference type="STRING" id="930090.W6Z7X6"/>
    <dbReference type="GeneID" id="19124171"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_42307"/>
    <dbReference type="eggNOG" id="KOG2346">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043566_0_0_1"/>
    <dbReference type="OrthoDB" id="203678at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990745">
        <property type="term" value="C:EARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014812">
        <property type="entry name" value="Vps51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="2" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU368010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="267" mass="29730" checksum="362F01F87F228C29" modified="2014-04-16" version="1" fragment="single">MSTIASPRPSSSVRTPSLTRTSIDSSSSHRPPPQPARRNRAALREFYGLKPAPKDVSADVRISEETTTNPLGPEEDETLTELDASDFNAEAYVESLLAREGLKGVLKVEADLISQIRNLDSDRKSLVYDNYSKLLSATSTIRRMRGNMDPLAPTTHTLGPAISHIAETAAALSSSLHESHQPKQEGLGISMRGEQDGAEADKKRKQKETVKWVLDTPRRLQILVDQEREEEAEKEWEEVSAILDKWKGVDGVQELREQCEAIMQEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7Y9</accession>
    <name>W6Z7Y9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Activating signal cointegrator 1 complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_4932</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687549.1">
        <property type="nucleotide sequence ID" value="XM_007689359.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z7Y9"/>
    <dbReference type="GeneID" id="19124434"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4932"/>
    <dbReference type="eggNOG" id="KOG0952">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000335_2_1_1"/>
    <dbReference type="OrthoDB" id="5575at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18020">
        <property type="entry name" value="DEXHc_ASCC3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18022">
        <property type="entry name" value="DEXHc_ASCC3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000198">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Activating signal cointegrator 1 complex subunit 3"/>
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    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000231">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000004">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000102">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000024">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000001">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000062">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF13">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039073">
        <property type="entry name" value="BRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="290"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="519"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="1150"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="1335"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1911"/>
            <end position="1931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1993" mass="223688" checksum="8BDBF0FB8A734A82" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z824</accession>
    <name>W6Z824_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FCP1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_100111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964021">
        <property type="protein sequence ID" value="EUC43699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689771.1">
        <property type="nucleotide sequence ID" value="XM_007691581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z824"/>
    <dbReference type="STRING" id="930090.W6Z824"/>
    <dbReference type="GeneID" id="19117609"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100111"/>
    <dbReference type="eggNOG" id="KOG1605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020262_7_0_1"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000089">
        <property type="entry name" value="NIF domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="275"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="467" mass="51609" checksum="8C7E0839D31C9A91" modified="2014-04-16" version="1">MGADRSNGSGSSTTEAVASGSNEKSPLLQQSQKGPYDDTTRRRRWLYPQLLSDGLTAIVGVLTTPFVYTGQYLIACFYYEDGHFSFLAPVYHVSRTFTRRRRKKVGAHAARASAATDNNEKAMRKGRSSSIAQPMAMQPSRRSLSIASTSTAMTSDSETERPASRGGDWDSPSQHTRSKSSALSRADEIAPAKRSIRITLHHNEDVLRQRKAAKKAQSSKSNSISSEAAASLKSPTGPATASSKQLTKFPRAPQPPRPLVPRRQPSYSAKGTSAVGPHQKTLIIDLDETLIHSIVNGGRFQTGHMVEVKLQASIGADGQVIGPQVPLLYYVHKRPYCDDFLKKVSKWYNLIIFTASVQEYADPVIDWLEVERKYFAGRYYRQHCTVRNGAYIKDLAQVEPDLSKVMILDNSPLSYVFHPDNAIPIEGWISDPTDHDLLHLIPLLEGLQYVTDVRALLALRLGMPASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z855</accession>
    <name>W6Z855_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_36368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687515.1">
        <property type="nucleotide sequence ID" value="XM_007689325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z855"/>
    <dbReference type="GeneID" id="19123003"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36368"/>
    <dbReference type="HOGENOM" id="CLU_2527125_0_0_1"/>
    <dbReference type="OrthoDB" id="3671388at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="84" mass="9234" checksum="4AA78A116D51B289" modified="2014-04-16" version="1">MATPLVPSKLADMLRQSIAPQFLEVIWGGPPNHKATKPSGVTAPRRYMRRDACFMSCTSGTTVSLAKHCKFYMAVALDEPVPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8J9</accession>
    <name>W6Z8J9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_109877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964208">
        <property type="protein sequence ID" value="EUC40016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693460.1">
        <property type="nucleotide sequence ID" value="XM_007695270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8J9"/>
    <dbReference type="STRING" id="930090.W6Z8J9"/>
    <dbReference type="GeneID" id="19119511"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109877"/>
    <dbReference type="HOGENOM" id="CLU_1907738_0_0_1"/>
    <dbReference type="OrthoDB" id="3780530at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="112" mass="13344" checksum="EE76FD85C63FEFE5" modified="2014-04-16" version="1" fragment="single">QLKIGPQRGLEFVRYITKLTKQGLIPKREVIKNLSSEVARQQLRESWVTRFMNRHEIHLIPNGTTVMDCTPHLADSESKYRLYFELLNRKITEYHLEAQDIYKMYKKGFFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8N7</accession>
    <name>W6Z8N7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Letm1 RBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_25574</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687088.1">
        <property type="nucleotide sequence ID" value="XM_007688898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8N7"/>
    <dbReference type="STRING" id="930090.W6Z8N7"/>
    <dbReference type="GeneID" id="19120785"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25574"/>
    <dbReference type="eggNOG" id="ENOG502S645">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048915_2_0_1"/>
    <dbReference type="OrthoDB" id="73691at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Letm1 RBD" evidence="9">
        <location>
            <begin position="242"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="62"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC46360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="409" mass="45911" checksum="DDCFD34AD58E73C8" modified="2014-04-16" version="1">MFPTLVKPLQSNGAFARSPRHRHLYTRAITTRLNCQIWHERSHHTTQQAGYEKIVGAQGRRYASSSAAPAKRTGHNITAAPPPLSKTNSTRVPAKTTPSRPLQAARNSPSSALPPAPVQQSKSATTPTLRALEKLNPPPFAYAPEISVPARKADQNLIKWLWTAGRAYLAFYKKGISHVRQTAKLAKSLRKKAAAHTPKKPMTEVLTRAEWQVVRRSRRDVLRLPVFGVLVLVLGEWLPVVVLYLTPVIPEVCRIPRQVERTLRKKEDKRQDRLRKIGLEAMRLVGRDRPATTVSADAASSAVAGTKGKSWKDMSLYELCVSAAKLDVYPAVFDWVPLAPPKFWMQRNVRRKLEYLETDYKLIERDGGIGGLNAEEVKRACVERGVKVLGRKEEELRRALAGVWAEMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z957</accession>
    <name>W6Z957_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_56232</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689368.1">
        <property type="nucleotide sequence ID" value="XM_007691178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z957"/>
    <dbReference type="STRING" id="930090.W6Z957"/>
    <dbReference type="GeneID" id="19124674"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_56232"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_18_9_1"/>
    <dbReference type="OrthoDB" id="21416at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF2">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="118" mass="12983" checksum="96442B2128584994" modified="2014-04-16" version="1" fragment="single">LAAEHGDTKILRTLRSVPGIDIHIKNVDGRTPLHIAALNNRVGAVKLLLGWDHKLLNARDNKNRTAYLLAAAKGHVKVLEVLKNKGQDMNQSTLKNGWTALHLAAEQGRVDAVKFLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9R9</accession>
    <name>W6Z9R9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-methyl-5'-thioadenosine phosphorylase</fullName>
            <ecNumber evidence="4">2.4.2.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">5'-methylthioadenosine phosphorylase</fullName>
            <shortName evidence="4">MTA phosphorylase</shortName>
            <shortName evidence="4">MTAP</shortName>
            <shortName evidence="4">MTAPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_35887</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-methyl-5'-thioadenosine + phosphate = 5-(methylsulfanyl)-alpha-D-ribose 1-phosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.28" evidence="4"/>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686970.1">
        <property type="nucleotide sequence ID" value="XM_007688780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9R9"/>
    <dbReference type="STRING" id="930090.W6Z9R9"/>
    <dbReference type="GeneID" id="19122893"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35887"/>
    <dbReference type="eggNOG" id="KOG3985">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054456_0_1_1"/>
    <dbReference type="OrthoDB" id="431409at2759"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00873"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1580:FF:000008">
        <property type="entry name" value="S-methyl-5'-thioadenosine phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01963">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018099">
        <property type="entry name" value="Purine_phosphorylase-2_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01694">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679:SF2">
        <property type="entry name" value="S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01240">
        <property type="entry name" value="PNP_MTAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 4" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="5">
        <location>
            <begin position="45"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="99"/>
            <end position="100"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="132"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="258"/>
            <end position="260"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="4">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="4">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="344" mass="37895" checksum="D704DEF9B84CF291" modified="2014-04-16" version="1">MLSRVNLAPSAFKLHNISRIWTRNISIPYRRMAGVPSTYDAPVHIAVIGGTGISSLPGFTLAATLDIDTPWGKPSSPISILQHPSPTTGKPIPVAFLSRHGLYHELAPHEVKNQANIAALRHIGVRTIIAFSAVGSLQEHVRPRDFLVPDQIIDRTKGIRPFTFFEGGMVGHVGFGDPFDKRLAALVRQCGHALEGEGVTLHDNGTLICMEGPQFSTRAESNLYRSWGGSVINMSALPEAKLAREAEIGYQMICMATDYDCWRGDGEEDVNVEMVMAHMKANAENARRFVGAVLNELSKEEHVDQVLAKHLDGQMRFAGAMTKKEGRGQEAEKKLQWLFPGYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAE9</accession>
    <name>W6ZAE9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964147">
        <property type="protein sequence ID" value="EUC40671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692813.1">
        <property type="nucleotide sequence ID" value="XM_007694623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAE9"/>
    <dbReference type="STRING" id="930090.W6ZAE9"/>
    <dbReference type="GeneID" id="19119204"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108213"/>
    <dbReference type="eggNOG" id="ENOG502S0KD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004286_7_1_1"/>
    <dbReference type="OrthoDB" id="3945870at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022198">
        <property type="entry name" value="DUF3723"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12520">
        <property type="entry name" value="DUF3723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="599" mass="69649" checksum="7DD50BD6C6065861" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAH2</accession>
    <name>W6ZAH2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SGS-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_35658</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SGT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686717.1">
        <property type="nucleotide sequence ID" value="XM_007688527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAH2"/>
    <dbReference type="STRING" id="930090.W6ZAH2"/>
    <dbReference type="GeneID" id="19122838"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35658"/>
    <dbReference type="eggNOG" id="KOG1309">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039532_3_1_1"/>
    <dbReference type="OrthoDB" id="1898560at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007699">
        <property type="entry name" value="SGS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044563">
        <property type="entry name" value="Sgt1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45862">
        <property type="entry name" value="PROTEIN SGT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05002">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
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    </dbReference>
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        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51048">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="172"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="SGS" evidence="3">
        <location>
            <begin position="290"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="344"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="41285" checksum="C4D8E13CFE50BFFD" modified="2014-04-16" version="1">MDDARKGDAALSASKPDEAIEHYTKALGVNPTAVKYYIGRSTAYQRTSKFPEALHDADVAVVLARKRGSRELIKDAQFRRAVALYHLGKYADADFLLRIVKGLDEKDKMLPIWEAKVASKLKDVPENDEQRTITIKENPDVEIPSTSTPSAPAKTADSATTQAPKPPAPTPKEKIKTDWYQSHDSVTLNIMAKGVPKDKAVVEIEQDSVSVSFPIADSSSEYSYNADPLFSSIDASQSKYRITPTKIEVTLRKATPGVKWHSLERAQGEAAAVTSQASSSVAPVKETAPAYPTSSKSGAKNWDKVVVNDLDDKDEIEGDETSHFFKQLYSGATPEQQRAMMKSYSESGGTVLSTDWSNVGNRKVVPEPPEGMEAKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAQ6</accession>
    <name>W6ZAQ6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable cytosolic iron-sulfur protein assembly protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CIA1</name>
        <name evidence="6" type="ORF">COCMIDRAFT_35473</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat CIA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAQ6"/>
    <dbReference type="STRING" id="930090.W6ZAQ6"/>
    <dbReference type="GeneID" id="19122790"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35473"/>
    <dbReference type="eggNOG" id="KOG0645">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_8_1"/>
    <dbReference type="OrthoDB" id="284782at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Probable cytosolic iron-sulfur protein assembly protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="CIAO1/Cia1"/>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920">
        <property type="entry name" value="WD40 PROTEIN CIAO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="62"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="135"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="180"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="320"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="411"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="439" mass="49499" checksum="4ECD84FF1542256A" modified="2014-04-16" version="1">MSPPADTQTHKLSRLATLTPPSNSRTWQSAPHPTLPIVATACSDRSVRVYSLTSFTLLHSITGGHKRSVRTVSWKPGTQGQSILATGSFDSSAGIWRREEQGGTLENDFTNRRMGNTEDDDGDDEAEDYQFSCILDGHESEIKCLSWSPSGQYLATCSRDKSVWIWEELEDDNFETVAVLQEHDGDVKCVAWHPEEDLLASASYDDTVRLYREDADDWVQVSMIDGHSQTVWWAEFEGSGMSKKDWRAQREGLSEEQTQYIENLERSGPRLATCSDDRTVRIWRRKAKERDDNSSSNTGIPSIIRSAAIDEDWYQEAILPRVHERAIYSVSWSRRTGMIVSAGSDGKIIVYKERWRQDASNTANGNQMELDAAQAQSPTEWTLVAELFSAHDVFEINHVAWARRVDQGKRSEDEEVVLSTGDDGEVRVWTLDEPARAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAQ8</accession>
    <name>W6ZAQ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_6100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688867.1">
        <property type="nucleotide sequence ID" value="XM_007690677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAQ8"/>
    <dbReference type="STRING" id="930090.W6ZAQ8"/>
    <dbReference type="GeneID" id="19124839"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6100"/>
    <dbReference type="eggNOG" id="ENOG502RXSX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016696_2_0_1"/>
    <dbReference type="OrthoDB" id="5375558at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF13">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="180"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="219"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="221"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="247"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="624" mass="68353" checksum="7DF7ACD9CDF22B26" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBJ4</accession>
    <name>W6ZBJ4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_107034</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI964119">
        <property type="protein sequence ID" value="EUC41111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692366.1">
        <property type="nucleotide sequence ID" value="XM_007694176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBJ4"/>
    <dbReference type="GeneID" id="19118967"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107034"/>
    <dbReference type="eggNOG" id="ENOG502S04V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041456_2_1_1"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="6">
        <location>
            <begin position="47"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="265" mass="29757" checksum="104746525DFFD0C2" modified="2014-04-16" version="1">MATTSKLPSPPPPSSTLPLGFLEGPAPNLTKSKIDFKEAGIPECEKSWAVVLDGVLTEEECETLIKGAEATTDGKWERAMVNVGGGMQAMYEDTRKCGRIIWDNEELMNKLWARIAPSVPEIHTLQNWVEVTGNGPTRRGETWVLTRLNERGRFLKYVGGEYFKPHCDGSYETPDGTERSYFTLHLYLNDAVGKDGETQLEGGATTFFSANMRKRVDVVPKVGRVLLFQHRLMIHSGDDVVRGQKFTLRTDIMYRVKDRSKETAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBL3</accession>
    <name>W6ZBL3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_106981</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="KI964118">
        <property type="protein sequence ID" value="EUC41136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692357.1">
        <property type="nucleotide sequence ID" value="XM_007694167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBL3"/>
    <dbReference type="STRING" id="930090.W6ZBL3"/>
    <dbReference type="GeneID" id="19118956"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106981"/>
    <dbReference type="eggNOG" id="KOG2867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030733_2_0_1"/>
    <dbReference type="OrthoDB" id="16120at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="371"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="372"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="398"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC41136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="491" mass="52797" checksum="FBBFC891743369D8" modified="2014-04-16" version="1">MASNPSQAPVLETIDKASGHEFALPAKRIHDGDDVTAFLASRAYADLMTFIFQLNTAMIPRKLDSKESGEAETAKEWTLNDKDVPYPPVVQNLAKLLDALTSIIDEAPPDPGPRRFGNVSFRTWYDIVRERASGLLDQHLPQHVLDFKSISDVSAKSELEAYFLGSFGSSQRLDYGTGHELSFLAFLGCLWKLGAFPESKDGDQERGIVLGVLEPYLVLIRRLILTYTLEPAGSHGVWGLDDHSFLPYIFGSAQFSPAISTPGDVAAEGSLPAAPNPGDVAKAPAVERERKRNMYFSAIGFIYDVKKGPFWEHSNILYDVSGVKAGWAKINKGMIKMYNAEVLSKFPVVQHFPFGSLFSFAPDPNARKIQATVHTASQPKASSATTPRPQPPLRDPLADTTATMPTATARPGGAVGTAAPWARGAPAAGPGVPSGVNQPTKAPWASRTTTTMMPGAGAGVGTAAPWARKKENGGGAGEGQQSTRAPWVDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBZ3</accession>
    <name>W6ZBZ3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_5810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688515.1">
        <property type="nucleotide sequence ID" value="XM_007690325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBZ3"/>
    <dbReference type="GeneID" id="19124746"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5810"/>
    <dbReference type="eggNOG" id="ENOG502QSXK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011027_0_1_1"/>
    <dbReference type="OrthoDB" id="1612078at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021102">
        <property type="entry name" value="PNGase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056948">
        <property type="entry name" value="PNGaseA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31104">
        <property type="entry name" value="PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25156">
        <property type="entry name" value="PNGase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12222">
        <property type="entry name" value="PNGaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-terminal" evidence="1">
        <location>
            <begin position="101"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="682" mass="74502" checksum="00BBAE521B821190" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC21</accession>
    <name>W6ZC21_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_3607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686048.1">
        <property type="nucleotide sequence ID" value="XM_007687858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC21"/>
    <dbReference type="GeneID" id="19122929"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3607"/>
    <dbReference type="eggNOG" id="ENOG502SRBF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1326124_0_0_1"/>
    <dbReference type="OrthoDB" id="3830579at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="24194" checksum="76DF574244975F04" modified="2014-04-16" version="1">MANSAERMAAHTQLLKTYLPAQDKPITEVAIFELKHPQSPETLRNFEQRIIANCQDGKGIKRMAWGFSLTDEKKLVWMLDWDKIQDHWDFWQTPAFTPVIQAIEDLFVEGRPLVRHYEFDPPGMLNQEYQRVLIWNQENRDIAAEQVLKSNGPTTTSTSIASNGAYAVDMDEDTWWCSNFGYTSEAEVRKDSVQDKGEAGIFKLKFSDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCP1</accession>
    <name>W6ZCP1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_3352</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685734.1">
        <property type="nucleotide sequence ID" value="XM_007687544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCP1"/>
    <dbReference type="GeneID" id="19122345"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3352"/>
    <dbReference type="eggNOG" id="ENOG502QUV4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_4_2_1"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889723" description="FAD-binding PCMH-type domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="189"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="657" mass="71788" checksum="2E7C541CF78BD171" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCZ2</accession>
    <name>W6ZCZ2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_36978</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688193.1">
        <property type="nucleotide sequence ID" value="XM_007690003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCZ2"/>
    <dbReference type="GeneID" id="19123155"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36978"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="57685" checksum="5CAEEE7C932E17D8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD21</accession>
    <name>W6ZD21_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">NIPSNAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_34613</name>
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    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NipSnap family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC47875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687390.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZD21"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="10262843at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000037">
        <property type="entry name" value="NIPSNAP family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051557">
        <property type="entry name" value="NipSnap_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017">
        <property type="entry name" value="NIPSNAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017:SF17">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <location>
            <begin position="157"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="NIPSNAP" evidence="3">
        <location>
            <begin position="237"/>
            <end position="334"/>
        </location>
    </feature>
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        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
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        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="336" mass="38484" checksum="C1D7D1CFEEF55E17" modified="2014-04-16" version="1">MLSRRACASVRGRLIPQPIATVRTRAFGATTAAQSPVRAPALADITPDSAASFNEKQKKFRDGLIAAQKRKEQEEKEARAREHENAKKKGGALSSLIYGTPEGRELDKDIERSFSQVLARGKYVHSIVFHEVKQENVEEYTELVGGWYPKMASIPENKVHLVGSWRTEVGDCNTFVHIWEYQRYEGYHESLHNIQSHPEFPAFDAKLKKLISGKRNSLMQEFSFWPTTPPRQLGGIFELRSYTLHPGNLLEWETHWRRGLKARREVMEGVGAWFVQIGDLNTVHHLWQFANLEERKIRREQSWSVEGWGETVHKTVPLIQTMKSSILIPCSWSPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD76</accession>
    <name>W6ZD76_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_89171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685692.1">
        <property type="nucleotide sequence ID" value="XM_007687502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD76"/>
    <dbReference type="GeneID" id="19127419"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89171"/>
    <dbReference type="HOGENOM" id="CLU_2941560_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="50" mass="5552" checksum="578B08AE4327D62C" modified="2014-04-16" version="1" fragment="single">TAHIDSSLTTIDKPNSAQLCHCRRRQRHQWPMHRARGATAVDASDAPLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDJ5</accession>
    <name>W6ZDJ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BCAS3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_88281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685448.1">
        <property type="nucleotide sequence ID" value="XM_007687258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDJ5"/>
    <dbReference type="STRING" id="930090.W6ZDJ5"/>
    <dbReference type="GeneID" id="19127232"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88281"/>
    <dbReference type="eggNOG" id="ENOG502QVCT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005319_0_0_1"/>
    <dbReference type="OrthoDB" id="3938623at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045142">
        <property type="entry name" value="BCAS3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13268:SF0">
        <property type="entry name" value="BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13268">
        <property type="entry name" value="BREAST CARCINOMA AMPLIFIED SEQUENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="744"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1093" mass="117966" checksum="EA913FBE1B420B8C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDM5</accession>
    <name>W6ZDM5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_3110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685480.1">
        <property type="nucleotide sequence ID" value="XM_007687290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDM5"/>
    <dbReference type="GeneID" id="19121800"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3110"/>
    <dbReference type="HOGENOM" id="CLU_2072725_0_0_1"/>
    <dbReference type="OrthoDB" id="3694282at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="126" mass="13717" checksum="9CB804C82228DA5A" modified="2014-04-16" version="1">MAAQTVHEDVTYPATLRTDDDGDISVVVVQPITYYQLATPAASRTPVLTAPITAPSKPRHAASDLLTSDNLAMQDNGFDPILDVAQKAAKALGLQRAGNELGFHLELQHYTNDRFDLNGWTTQQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDQ5</accession>
    <name>W6ZDQ5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_88055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685340.1">
        <property type="nucleotide sequence ID" value="XM_007687150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDQ5"/>
    <dbReference type="GeneID" id="19127191"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88055"/>
    <dbReference type="HOGENOM" id="CLU_2468715_0_0_1"/>
    <dbReference type="OrthoDB" id="10339943at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886761" evidence="1">
        <location>
            <begin position="19"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="88" mass="9519" checksum="713D59F0494D30BA" modified="2014-04-16" version="1">MKFTTAFLLAASVNVITALTASFDGCNYNGRGATSYANGPCTKEICGHIDCQMACHQAGIHDSPNDYYLGVNYNGYIQNSCSCVCYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDQ8</accession>
    <name>W6ZDQ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DSBA-like thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_88128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685342.1">
        <property type="nucleotide sequence ID" value="XM_007687152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDQ8"/>
    <dbReference type="GeneID" id="19127207"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88128"/>
    <dbReference type="eggNOG" id="ENOG502RG41">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_647619_0_0_1"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051924">
        <property type="entry name" value="GST_Kappa/NadH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42943">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42943:SF2">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA-like thioredoxin" evidence="1">
        <location>
            <begin position="7"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="DSBA-like thioredoxin" evidence="1">
        <location>
            <begin position="255"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="DSBA-like thioredoxin" evidence="1">
        <location>
            <begin position="373"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="504" mass="55676" checksum="7791074BC535D125" modified="2014-04-16" version="1">MASPPPTLIFNYDISCPFAYIASTRVQSLAHRTNATLLYHPVLLGAIYRATAAPQGAGGSASDVFNATKKTVAGQSMQRTLARYQVPYHPPPQHPRKTVNALRMLYCVPEQDKRRELTDRLFRAYWVEGRDVNDDAVLLQIASEAGVKGLDRTCFKDVTARGELERETGLAIERGAFGVPGFWIPEAEGGDGRFFWGQDRMHFVEATLLGLSSSSGVKGKEGEDAWTRVGNLRGLLPRVVGENRLPLASKPVARLEFWFDFSSPWAFLGYTQLARLQRTFGPGLEIVLKPFLLGILFREIGAPNMPMMAISQAKAEWSRRDHVDWTRWWNAVDVQEGQQQGGRGKDGPIKFYWADKFPIRTPTVLRVGIVEPAATKVLYSACWEQNKDVADESVLQSVLDEAGFNGADLIARANSPATKEKLRALTAEAKELGLCGAPTYRVLRRQQNGEFKPVGGLVWGQDETNVVEDLIAGWSPEESNGQIAEVGKVRYDDVQGGKGVGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDX7</accession>
    <name>W6ZDX7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Clp R domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_94979</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687851.1">
        <property type="nucleotide sequence ID" value="XM_007689661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDX7"/>
    <dbReference type="STRING" id="930090.W6ZDX7"/>
    <dbReference type="GeneID" id="19128554"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94979"/>
    <dbReference type="eggNOG" id="KOG1051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_2_1"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140602">
        <property type="term" value="C:nucleolar peripheral inclusion body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140453">
        <property type="term" value="C:protein aggregate center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
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    </dbReference>
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        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
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        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
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        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
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        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CLPPROTEASEA"/>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="10">
        <location>
            <begin position="4"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="888"/>
            <end position="920"/>
        </location>
    </feature>
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        <location>
            <begin position="427"/>
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        </location>
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        <location>
            <begin position="893"/>
            <end position="920"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
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        <source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="920" mass="102459" checksum="E9A9B06FF656A520" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE95</accession>
    <name>W6ZE95_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_105054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964083">
        <property type="protein sequence ID" value="EUC41851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693439.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_105054"/>
    <dbReference type="HOGENOM" id="CLU_2867329_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="64" mass="7328" checksum="9F89254C6F3E0DB7" modified="2014-04-16" version="1">MYRLLCGNRSRTPPPLPRVEMRCLYGASKKGPQKAIPSGVHKQRRHTIRLGRLHLYNTSAQINC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF40</accession>
    <name>W6ZF40_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor CWC22</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Pre-mRNA-splicing factor cwc22</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_93711</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963971">
        <property type="protein sequence ID" value="EUC46129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687365.1">
        <property type="nucleotide sequence ID" value="XM_007689175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF40"/>
    <dbReference type="STRING" id="930090.W6ZF40"/>
    <dbReference type="GeneID" id="19128314"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93711"/>
    <dbReference type="eggNOG" id="KOG2140">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006308_2_1_1"/>
    <dbReference type="OrthoDB" id="3938623at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000004">
        <property type="entry name" value="pre-mRNA-splicing factor CWC22 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF3">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="MI" evidence="10">
        <location>
            <begin position="414"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="611"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="633"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC46129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="689" mass="78143" checksum="4DA512C33457312E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFD3</accession>
    <name>W6ZFD3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_36165</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687297.1">
        <property type="nucleotide sequence ID" value="XM_007689107.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZFD3"/>
    <dbReference type="GeneID" id="19122961"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36165"/>
    <dbReference type="eggNOG" id="KOG1147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002839_0_0_1"/>
    <dbReference type="OrthoDB" id="6129702at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1160.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.800.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000037">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000004">
        <property type="entry name" value="Glutamyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000168">
        <property type="entry name" value="SH3 domain protein (Cyk3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.620.30:FF:000005">
        <property type="entry name" value="SH3 domain protein (Cyk3), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="entry name" value="Glutamyl-trna Synthetase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.800.10">
        <property type="entry name" value="Glutamyl-tRNA Synthetase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056409">
        <property type="entry name" value="Ig_CYK3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF5">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24584">
        <property type="entry name" value="Ig_CYK3_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="16">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="127"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="299"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="347"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="926"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="147"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="381"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="431"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="952"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="968"/>
            <end position="986"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC46204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1691" mass="187617" checksum="4F205D8F1BBF3863" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFZ3</accession>
    <name>W6ZFZ3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_92753</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC46434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688866.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZFZ3"/>
    <dbReference type="GeneID" id="19128135"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92753"/>
    <dbReference type="eggNOG" id="KOG3401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093240_0_1_1"/>
    <dbReference type="OrthoDB" id="1688503at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:structural constituent of ribosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_uL24_A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="KOW"/>
    </dbReference>
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        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
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        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="135" mass="15189" checksum="5491D3A4A86F1439" modified="2014-04-16" version="1">MTKVQSLVASSRRKSRKAHFSAPSSVRRVIMSAPLSKELREKHGVRSIPIRKDDEITVVRGSNKGREGKVSSVYRLKYCIHVNGIVREKSNGQSVPIPIAASKVVITKLKLDKDRESILERKSAGREEKKKQREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG59</accession>
    <name>W6ZG59_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_31997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG59"/>
    <dbReference type="STRING" id="930090.W6ZG59"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_31997"/>
    <dbReference type="HOGENOM" id="CLU_882747_0_0_1"/>
    <dbReference type="OrthoDB" id="3695659at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="309" mass="33490" checksum="E8F8ACB81AC72E38" modified="2014-04-16" version="1">MAHSNPSNMLNPDAPAFSPSSIPSQQASDQHQYRFQVLQEPYIYEGTSYYTNPPQILLPTPSLQQSSQQPPSQPLPSQPLPSQAHGCHNSSSSSGSNHSNSNGNGYSSNGYSSGYNSPSQIGSTTLHNNLYAHFTTTNRTVPFHDSQTITLSSNGHHYFPFHNHYNYKNNHYSNNSPSYNPYPVNYSNFGPFSTPTKQVGGVNNGFRNQHNTTNGHGGIWQQQPNNDRGKKSKKNKRKKHGKGWGKKNDEANGDELDTDKTNGDGAGGNHANGAEANGGETNGGETNDNGTLDGDTSNGCDGKSEEEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG66</accession>
    <name>W6ZG66_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase II subunit RPB3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_39446</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964059">
        <property type="protein sequence ID" value="EUC42496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690976.1">
        <property type="nucleotide sequence ID" value="XM_007692786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG66"/>
    <dbReference type="STRING" id="930090.W6ZG66"/>
    <dbReference type="GeneID" id="19123691"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39446"/>
    <dbReference type="eggNOG" id="KOG1522">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038421_1_1_1"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07031">
        <property type="entry name" value="RNAP_II_RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00072506"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="332" mass="35933" checksum="E0ABF726FA102090" modified="2014-04-16" version="1">MDYDPDGGQINVRFLQADNQRAHFIVQNFNLETANALRRVMLAEIPTLAIDVVEVFDNTSVLADEFVCHRLGLIPLSSKGVDDLLYSRDCDCEGYCDNCSVVLTLNAKCTGSEVMKVYARDLVIESRPPNDELGRPVITDSEGTGSCIVKLRRGQAINMKCIAKKGIAKEHAKWAPSAAIGFEYDPANKLHHLDYWHEEDAEKEWPKDEARVNLDGGPPNPDEPFNYNAVPTRFFYDVETVGGIEPDQIVTKGIQRLQIKLAEVLKELSGGIGDHEDFGGAQSPMMNGGGYGDAGGYTPVGGPGGYGGASSWGGAAQGGTTPYGATPYGQGW</sequence>
</entry>
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    <accession>W6ZGL2</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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            <end position="30"/>
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            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="66" mass="6805" checksum="A479703517AD8671" modified="2014-04-16" version="1">MGAVVSCIKSIFRTIGNCIMAIVNAIAAGLKAIINAIVSLFGIIISCLTCGRGGGGRRRTTHTSRV</sequence>
</entry>
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    <accession>W6ZGT8</accession>
    <name>W6ZGT8_COCMI</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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            <end position="496"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="559"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49245.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="778" mass="85664" checksum="AB3AFA14A353DF81" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHI9</accession>
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    </protein>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886861" evidence="1">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="112" mass="12365" checksum="D715EFC1C74551DA" modified="2014-04-16" version="1">MKSVLAALLMSASLAFAQVPNSPSRNPYCGRSRPMYYYNLPSDGTPNCNQCRDLNNYPRFFNFFQCKTPGTMPHVDYFTCDSKNGLCITYWAAPSTTVSVGEAEASAQGRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHN5</accession>
    <name>W6ZHN5_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="8" type="ORF">COCMIDRAFT_79405</name>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684056.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_79405"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000018">
        <property type="entry name" value="MFS transporter permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="57"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC51362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="508" mass="55632" checksum="8C2DEEFE470671DD" modified="2014-04-16" version="1">MAPFSTKRYYAGESQDEEKVDTVAVEKNGDGIPDAPVTGEIDPVIAKRVRRKLDKHVVPLLAALYLLAFLDRSNIGNARIAGMEEDLHLSSSEYSWLLTIFYISYIVFGFLIVMWKVVPPHRWAAGCVFAWGLISSAQAGAQSWTGMMVLRFLMGVAEIAFGPGVPFLLSFFYLRHELGLRCGLFLSAAPLANTFSGALAYGITSGNPSFAKWRVLFLVEGLPTVVMSVVTWFFLPDSPEKARFLTEEEKAVAKARGVAQAGTGTRIGSIEWKEMLEAVLDLKSWVLGIMYFSGNVAFSSLPVFLPTILTEMGFSHVNAQGLTAPPFFVSFITVIVTCYIADRTQQRGIMIAILTAIGGAGYIILATTKAVAARYFGVFLAAAGIFPAIGNVLPWITNNQGTDTRRGTGLMMANLIGQCGPVLGTRLYPKSEGPLYVKGQSICAGFMFLFCLLAILLRTLLAWENKKLDRRYGTLAQQKSAMQEAAKGREAVHQIGLENYGPMYRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHP4</accession>
    <name>W6ZHP4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_31511</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpF family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682150.1">
        <property type="nucleotide sequence ID" value="XM_007683960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHP4"/>
    <dbReference type="STRING" id="930090.W6ZHP4"/>
    <dbReference type="GeneID" id="19121883"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31511"/>
    <dbReference type="eggNOG" id="ENOG502QWDT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_312143_0_0_1"/>
    <dbReference type="OrthoDB" id="4161332at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007400">
        <property type="entry name" value="PrpF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF86">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04303">
        <property type="entry name" value="PrpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="10">
        <location>
            <begin position="149"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="455"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="851"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="466"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC51377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="927" mass="102090" checksum="31731490B129645E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHP6</accession>
    <name>W6ZHP6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_84493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684026.1">
        <property type="nucleotide sequence ID" value="XM_007685836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHP6"/>
    <dbReference type="GeneID" id="19126475"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84493"/>
    <dbReference type="eggNOG" id="ENOG502S2DA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071858_2_0_1"/>
    <dbReference type="OrthoDB" id="3438781at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886868" evidence="1">
        <location>
            <begin position="17"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="274" mass="28149" checksum="4A0FBE80F1121B8C" modified="2014-04-16" version="1">MIPKYLSLALAAVAAASPFEGFKKDDEASYKACTPQGATTETPPSVGPGLSSLYTNVVASVQGISFQPRSINERAEGFACHPSLDCVNLQNLNIPMCYDKFTTNFQFPDGSYGTIATGDYHSGGTDVNLISGNYTKDGQSANIYSGNEAERPNTSTMSIPPQFTGTGVGGAIPVSELGSIVVFTTTLPPVTYTAPTTVAESVATATVGGQQIETTIPATTITQATTVAGRTAVVTETRTDAAQPTKTGGAGCVGIDGTASFGMSLLGALMYALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHV3</accession>
    <name>W6ZHV3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_3989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="Han J."/>
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                <person name="Lindquist E."/>
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</entry>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC47414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686122.1">
        <property type="nucleotide sequence ID" value="XM_007687932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ03"/>
    <dbReference type="GeneID" id="19127669"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90366"/>
    <dbReference type="HOGENOM" id="CLU_2621846_0_0_1"/>
    <dbReference type="OrthoDB" id="10343805at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="80" mass="9075" checksum="45898E7FB7101BCC" modified="2014-04-16" version="1">MPLRADLVILPRTDVQFILAMSKPGQAYTEPYPDQESVHMYSLHKIMCHARCNIYTGPRNRQFALDSIFGVAGGHTRLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ36</accession>
    <name>W6ZJ36_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="7">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_6984</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="7"/>
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        <property type="protein sequence ID" value="EUC43611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689864.1">
        <property type="nucleotide sequence ID" value="XM_007691674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ36"/>
    <dbReference type="STRING" id="930090.W6ZJ36"/>
    <dbReference type="GeneID" id="19125145"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6984"/>
    <dbReference type="eggNOG" id="KOG0169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002738_3_1_1"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="C2_domain_sf"/>
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        <property type="entry name" value="PI-PLC_fam"/>
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        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF169">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="302"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00059664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC43611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="574" mass="63989" checksum="3ADE7689BCA084DC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ41</accession>
    <name>W6ZJ41_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism evidence="8 9">
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964024">
        <property type="protein sequence ID" value="EUC43616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ41"/>
    <dbReference type="STRING" id="930090.W6ZJ41"/>
    <dbReference type="GeneID" id="19117663"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100376"/>
    <dbReference type="eggNOG" id="KOG1175">
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    <dbReference type="HOGENOM" id="CLU_000022_3_3_1"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030729">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acac_CoA_synth"/>
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        <property type="entry name" value="AMP-bd_C_sf"/>
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        <property type="entry name" value="AMP-binding_CS"/>
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    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
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        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01217">
        <property type="entry name" value="ac_ac_CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002937">
        <property type="entry name" value="PRK03584.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921:SF1">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="7">
        <location>
            <begin position="49"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="117"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="75938" checksum="A2015F299102B251" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJF7</accession>
    <name>W6ZJF7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein P1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">60S acidic ribosomal protein P1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_100113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the elongation step of protein synthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">P1 and P2 exist as dimers at the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964021">
        <property type="protein sequence ID" value="EUC43716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689780.1">
        <property type="nucleotide sequence ID" value="XM_007691590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJF7"/>
    <dbReference type="STRING" id="930090.W6ZJF7"/>
    <dbReference type="GeneID" id="19117611"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100113"/>
    <dbReference type="eggNOG" id="KOG1762">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114656_1_0_1"/>
    <dbReference type="OrthoDB" id="2194681at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006414">
        <property type="term" value="P:translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05831">
        <property type="entry name" value="Ribosomal_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="120" mass="12068" checksum="48B5C31B41CE73A5" modified="2014-04-16" version="1">MSTAELASSYAALILADDGVEITADKLQSLIKAAKVEDVEPIWTSLFAKALEGKDVKDLLLNVGSGGGAAAPAAAGGAAAAGGAADAAPAAEEKKEEDDPTNTPTEKEESDEDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJS7</accession>
    <name>W6ZJS7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_82398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683185.1">
        <property type="nucleotide sequence ID" value="XM_007684995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJS7"/>
    <dbReference type="STRING" id="930090.W6ZJS7"/>
    <dbReference type="GeneID" id="19126042"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82398"/>
    <dbReference type="eggNOG" id="KOG0789">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001645_11_0_1"/>
    <dbReference type="OrthoDB" id="6058203at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01446">
        <property type="entry name" value="DSP_MapKP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18533">
        <property type="entry name" value="PTP_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000051">
        <property type="entry name" value="Protein tyrosine phosphatase (Pyp1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF561">
        <property type="entry name" value="PROTEIN TYROSINE PHOSPHATASE 36E, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="6">
        <location>
            <begin position="289"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="546"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="738"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="159"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="651"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="797"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="870" mass="96114" checksum="8563C8A3A00BD8ED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK65</accession>
    <name>W6ZK65_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_32226</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683019.1">
        <property type="nucleotide sequence ID" value="XM_007684829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK65"/>
    <dbReference type="GeneID" id="19122053"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32226"/>
    <dbReference type="eggNOG" id="ENOG502QT05">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036005_0_0_1"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000907">
        <property type="term" value="F:sulfonate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044273">
        <property type="term" value="P:sulfur compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000003">
        <property type="entry name" value="Alpha-ketoglutarate-dependent taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="91"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="382" mass="42729" checksum="B66C41580233FA74" modified="2014-04-16" version="1">MAPAVIATPPTDYKSGVGAYKEFGLGGPKFFQKELELKGTEKHSPAKYPHYLPVWDNEKGQKLPPWEPFTHVEHGKDADPTFSNLLKNATVNDLTANTGAEVHGVQLSQLTNAQKDELALFVAKKKVVAFRDQDFADLPIKDALEIGGYFGRHHIHPTSGAPEGYPEVHLVHRGTDDTSVRDFFEERTNSVAWHSDVTYEKQPPGTTFLYILDGPEAGGDTLFANQAAAYQRLSPEFRKRLHGLKVVHSAVEQAESSKLRGGIVRRDPVTSIHPLVRTHPATGEKALFVNPQFSRRIVGFKKEESEYLLNFLYDHIAKGQDFQVRVKWAPGTVVVWDNRVTAHSALLDWDDGARRHVARITPQAEPPYETPFEEEGAATFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK81</accession>
    <name>W6ZK81_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_81800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683090.1">
        <property type="nucleotide sequence ID" value="XM_007684900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK81"/>
    <dbReference type="GeneID" id="19125936"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81800"/>
    <dbReference type="HOGENOM" id="CLU_2867330_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="64" mass="6717" checksum="37A97A4264DAF6AD" modified="2014-04-16" version="1">MAITPKIQKNPSFPLPLNDIPVPSPLDPETTKATFWPEPVPLQSPGAGGTAMPHSCLTLPSVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKC5</accession>
    <name>W6ZKC5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_32271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683029.1">
        <property type="nucleotide sequence ID" value="XM_007684839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKC5"/>
    <dbReference type="STRING" id="930090.W6ZKC5"/>
    <dbReference type="GeneID" id="19122063"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32271"/>
    <dbReference type="eggNOG" id="ENOG502SF32">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070640_0_0_1"/>
    <dbReference type="OrthoDB" id="1733656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890094" evidence="1">
        <location>
            <begin position="18"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="267" mass="28919" checksum="DA77D30371F58085" modified="2014-04-16" version="1">MRVSSGILLALPALAVAEEQQIPILDKVKGFFNKASAAVSSTISASMPSAPVEAASEAAAKVVEVIQHPLTLENWKDVLTVDPTASPPTTQDWLVFTTGGNNTCFGLCGNATKAWNASTPFIAAMPNAPKLAYLDCETEGILCNSWSIHAPSLYLFQIPKPLPDQSAPVPVARYQALNRTTTTAETIKKLIVDNEIAEIEPYWGHFHPFNGTMQQYNLAVPYGYFTYGFSKMPSWLPMIIISFVSRSFMGNRMAGGPTPAQRAPGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKC9</accession>
    <name>W6ZKC9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribonuclease P protein subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_693</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682795.1">
        <property type="nucleotide sequence ID" value="XM_007684605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKC9"/>
    <dbReference type="STRING" id="930090.W6ZKC9"/>
    <dbReference type="GeneID" id="19125128"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_693"/>
    <dbReference type="eggNOG" id="KOG4046">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078577_0_0_1"/>
    <dbReference type="OrthoDB" id="124041at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
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            <end position="77"/>
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    </feature>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    <sequence length="231" mass="26107" checksum="400FC41F61F0E36F" modified="2014-04-16" version="1">MANSNPHIAQTLLHRAFSPSTAESHYQERAVQRPLYVRATSPTPSARAVRRQALNERKEAARKRSKNKPRPLSAAKKRALGLNEISREQQKYAIYEGLHNLWVGYMREVLGVNDVSKGVVITPNASGQILATADMHGALMTVVRSRCVSRVGLEGIVVRDTRFTFDLITKNNIIKSVPKEHTIFRFEVPLLSNEGEPPKKPLTFDINAEQFQTRAADRANKKFRIHYQPDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLE7</accession>
    <name>W6ZLE7_COCMI</name>
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        <recommendedName>
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        </recommendedName>
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        <name evidence="3" type="ORF">COCMIDRAFT_21611</name>
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            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="term" value="F:histone acetyltransferase activity"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF15460"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50895.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="538" mass="59089" checksum="091F783994B8C168" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMB4</accession>
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        <recommendedName>
            <fullName evidence="6">Transcription factor</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism evidence="10 11">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:sequence-specific DNA binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-0804">Transcription</keyword>
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    <keyword evidence="3" id="KW-0902">Two-component regulatory system</keyword>
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        <location>
            <begin position="353"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="257"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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            <end position="570"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="506"/>
            <end position="518"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="629"/>
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    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="403"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC51220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="648" mass="72791" checksum="6ECD69A4C7E88F41" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMS4</accession>
    <name>W6ZMS4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Diphthine methyl ester synthase</fullName>
            <ecNumber evidence="4">2.1.1.314</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Diphthamide biosynthesis methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_31430</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="EC" id="2.1.1.314"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diphthine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.314" evidence="4"/>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682133.1">
        <property type="nucleotide sequence ID" value="XM_007683943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMS4"/>
    <dbReference type="STRING" id="930090.W6ZMS4"/>
    <dbReference type="GeneID" id="19121866"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31430"/>
    <dbReference type="eggNOG" id="KOG3123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066040_1_0_1"/>
    <dbReference type="OrthoDB" id="2516at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141133">
        <property type="term" value="F:diphthine methyl ester synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000004">
        <property type="entry name" value="Diphthine synthase putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000004">
        <property type="entry name" value="Putative diphthine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01084">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882:SF0">
        <property type="entry name" value="DIPHTHINE METHYL ESTER SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="DIPHTHINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036432">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="12">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR036432-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC51288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="286" mass="32097" checksum="252E56C65B861E0A" modified="2014-04-16" version="1">MLYLVGLGLADEKDITVKGLDIVKKAERVYLEAYTAVLLVEKDVLEAFYGREVIIADREMVESSSDDILKDADKVDVAFLVVGDPFGATTHTDLVLRARELSIPTRSIPNASILTSIGTTGLQLYNFGQTVSMVFFLDNWKPASFYDRIKENVSIGLHTLVLLDIKVKEQSLENMARGRKIYEPPRYMSVAQCAQQMLEIEEDVKQEGAYTKDSLAVGVARVGAEDQQIVAGTLEQLCEADLGKPLHSLVLLGKRTHDLERDFLEEFAVDKEKFKEIWKRDYEGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN88</accession>
    <name>W6ZN88_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_37182</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963992">
        <property type="protein sequence ID" value="EUC45041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688432.1">
        <property type="nucleotide sequence ID" value="XM_007690242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN88"/>
    <dbReference type="STRING" id="930090.W6ZN88"/>
    <dbReference type="GeneID" id="19123195"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37182"/>
    <dbReference type="eggNOG" id="ENOG502QR1M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004517_0_0_1"/>
    <dbReference type="OrthoDB" id="5373550at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14723">
        <property type="entry name" value="ZIP_Ppr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000006">
        <property type="entry name" value="Positive regulator of purine utilization"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF1">
        <property type="entry name" value="PYRIMIDINE PATHWAY REGULATORY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
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                <person name="Salamov A."/>
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                <person name="Han J."/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
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        </location>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
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    </evidence>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="EMBL" id="EUC45376.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="370" mass="41785" checksum="8B8176356C032A87" modified="2014-04-16" version="1">MASVTAPSPVPKEEPVDANANNSNNEGLSPADALYEKCAQRPAGQIFFQRDLSNMQVADTVTQLMELLQELSDRHLLKHMTFEGLTCWKLRTREEADKLRRLTPDERLLYQYIDQAQTEGIWSKVLRSRTNVTQQTLTKCLKNLESKDLVQSVMSVKHPNRKMYLLKHLKPSEEIAGGPWQSEGDFDMALIDTISGIVAQHVENETCIRVPGNWNDYDITEDRTAAIARKKAQVQGVPDIEDIAPAVKPHRPSKDPNVTKLVHRHNPQYPTAASVANWLNSKEILRGKTVREDDMEQLLEMMVLDDRLEKISGTNYRTVLRATDTKVYNGFVDAPCGNCPVFDLCGDEGEISARTCVYFGQWLGTESEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRZ4</accession>
    <name>W6ZRZ4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS19m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_4498</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687016.1">
        <property type="nucleotide sequence ID" value="XM_007688826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRZ4"/>
    <dbReference type="STRING" id="930090.W6ZRZ4"/>
    <dbReference type="GeneID" id="19124260"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4498"/>
    <dbReference type="eggNOG" id="KOG0899">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144911_1_2_1"/>
    <dbReference type="OrthoDB" id="2043at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF8">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="93" mass="10552" checksum="67242B9D8456B70B" modified="2014-04-16" version="1">MFPTRVLCARSVWKGPNIVPLPIVQKKAGERVPPIKTQARSATILPNFVGLKFQIHNGKSYLDITITEDMVGHKLGEFAPTRKQFMYKQTKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSY4</accession>
    <name>W6ZSY4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pantoate--beta-alanine ligase</fullName>
            <ecNumber evidence="3">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Pantoate-activating enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pantothenate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_21942</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(R)-pantoate + beta-alanine + ATP = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="3"/>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682830.1">
        <property type="nucleotide sequence ID" value="XM_007684640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSY4"/>
    <dbReference type="STRING" id="930090.W6ZSY4"/>
    <dbReference type="GeneID" id="19120142"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21942"/>
    <dbReference type="eggNOG" id="KOG3042">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047148_1_2_1"/>
    <dbReference type="OrthoDB" id="2020436at2759"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1300.10:FF:000002">
        <property type="entry name" value="Pantoate--beta-alanine ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="entry name" value="Pantoate-beta-alanine ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299">
        <property type="entry name" value="CYTIDYLATE KINASE/PANTOATE-BETA-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PANTOATE--BETA-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC50634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="308" mass="34822" checksum="710A764AFB708B86" modified="2014-04-16" version="1">MGALHEGHISLMRHAAAENTDVFVTIYVNPTQFGLNEDLDSYPKTWETDLRIVEQLNQELASSGQGRVTAIFAPETKTMYPTLPPDSSIPGVGTFVEMRPLGQILEGASRPVFFRGVATVCMKLFNICAPDRVYFGQKDVQQTRVIKRMITDFHLDMDLRIIPTSRESDGLALSSRNVYLGTRRRNVAIVLNQALRKAEIKYKNGMRLRNDVLWPAFDHTNMTLLDQEQLEPNQRAKFEVDYISLADPDTMEEIEQIDDSKGAILSGVVKMLPVEEPQPDKEDLGRLDAEGHQVPVRLLDNIILEPMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTJ5</accession>
    <name>W6ZTJ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">4-nitrophenylphosphatase</fullName>
            <shortName evidence="5">PNPPase</shortName>
            <ecNumber evidence="3 5">3.1.3.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_3910</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21664"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57917"/>
            <dbReference type="ChEBI" id="CHEBI:61146"/>
            <dbReference type="EC" id="3.1.3.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Divalent metal ions. Mg(2+) is the most effective.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.41" evidence="3 5"/>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686380.1">
        <property type="nucleotide sequence ID" value="XM_007688190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTJ5"/>
    <dbReference type="STRING" id="930090.W6ZTJ5"/>
    <dbReference type="GeneID" id="19123615"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3910"/>
    <dbReference type="eggNOG" id="KOG2882">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043473_0_0_1"/>
    <dbReference type="OrthoDB" id="413953at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000039">
        <property type="entry name" value="Phosphoglycolate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006349">
        <property type="entry name" value="PGP_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01452">
        <property type="entry name" value="PGP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00050247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00066659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00069197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC47051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="304" mass="32733" checksum="FC1C1E773CA08163" modified="2014-04-16" version="1">MASPQFLSGDKAAIDGFLDRFDVFLFDCDGVLWSGDHLFDKVPETLEMLRGKGKQLVFVTNNSTKSRADYKKKFDKLGIPANVDEVFGSSYSAAVYIARILKLPGPKNKVFVLGESGVEQELESEGVPYIGGTDPAYRRDIRQPEDFDAIANGTLLDPDVGIVLSGLDFHSNYLKTAIAFQYLQRGAVYLATNIDSTLPMSHTLFPGAGSSGAALERAIGRAPLSLGKPSQAMMDAVEGKFKFDRSRTCMIGDRLNTDIQFGIDGKLGGTLAVLTGVSKKEDFLAEGAPTVPTAYVNALGDLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZXG6</accession>
    <name>W6ZXG6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_87050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684980.1">
        <property type="nucleotide sequence ID" value="XM_007686790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZXG6"/>
    <dbReference type="GeneID" id="19126975"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87050"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_10_1_1"/>
    <dbReference type="OrthoDB" id="5357513at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="25"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="299" mass="33793" checksum="4F39CF213B2A8AF0" modified="2014-04-16" version="1">MASLSTTNRMSRLHDDKPAFIYGTAWKEDQTKRLVKEALAVGFRRVDTAAQPRHYQEALVGEALREAFTEGLLKREELYLQTKYTHPEGQDPDNMPYDPNAPLDSHIRTSVASSLKNLQHAANSPEDSYLDCLLLHSPLPTVEETIQAWKLLETYVPHRIRSLGISNVALPILQIIHQNATVKPAVVQNRFYPKKRYDMTLRDFCRAHDIVYQSFWTLTGNPILLQSQPVAALAKAAQIEVPVALYALVIDQGVMVLNGSTSREHMEMDLEGVQKVREWAVENPGEFAAIVREFKAMMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZR0</accession>
    <name>W6ZZR0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_60795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684362.1">
        <property type="nucleotide sequence ID" value="XM_007686172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZR0"/>
    <dbReference type="GeneID" id="19124826"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_60795"/>
    <dbReference type="HOGENOM" id="CLU_1277527_0_0_1"/>
    <dbReference type="OrthoDB" id="3800368at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="181" mass="20583" checksum="0B83FF41FA6218DE" modified="2014-04-16" version="1" fragment="single">HISGWNPINRISETSVGDWAYREPDPEYGLHNALDEEPVHPSLEEKYLDHYGCLNYINSMHKLTWTKEKLADEERAEQSNNVWGQDPVARKHGTPIKRPWDVEEDAWLDLFHEKIRGAIEAGAVIKIPGRGPVLEAFNAFFKRKRLEEGDEPAAAAAAGESEWTPRTIGSMHRKLRFGGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2V0</accession>
    <name>W7A2V0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peptide hydrolase</fullName>
            <ecNumber evidence="13">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_82464</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M28 family. M28A subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="13"/>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683206.1">
        <property type="nucleotide sequence ID" value="XM_007685016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2V0"/>
    <dbReference type="GeneID" id="19126056"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82464"/>
    <dbReference type="eggNOG" id="KOG2195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024336_0_0_1"/>
    <dbReference type="OrthoDB" id="10013407at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03876">
        <property type="entry name" value="M28_SGAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02130">
        <property type="entry name" value="PA_ScAPY_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000054">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041756">
        <property type="entry name" value="M28_SGAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF26">
        <property type="entry name" value="PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 13" id="KW-0732">Signal</keyword>
    <keyword evidence="11 13" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005151141" description="Peptide hydrolase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="14">
        <location>
            <begin position="126"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="239"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC50316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="496" mass="53238" checksum="FC3847B340214717" modified="2014-04-16" version="1">MAYLKSIAAFAACAAAVEAAALHPRTNKTLVDSQSLRDTIDIDNLFAKAEILQEIAYNTPGKNRVIGSQGHEDTVEYIKGQLEAFPDYYDVYTQDVPLSIGTTATLRANNNTIEAFAVTLAPGGNVTGPLVAIPNLGCEEADFPESLSGSVALIKRGTCSYGEKVQIAAAKGALGVVAWNNAEGTLEGYSLQVLYPKGKFVPVAGITMGQGEALLAQLNAGVKINIDMSTDAKVFNTRNVIAETKAGDHDNVIHVSGHSDSVTAGPGINDNGSGTISILEIAIQLTNFTVNNAVRFSWWTAEEAGLLGAEYYVHELPQAEKDKIRLLLDFDMMASPNFAYQIYDGDGSAYNLTGPVGSAEAEHEFAAYFDSIGLNHTEIEFDGRSDYGPFLEAGIASGGIAGGAEGIKTEEEAAMFGGGAGVPYDVNYHEDGDTVNNLNLEAWIEFTRAIAHMTAKYAVSWDSIPPRNATAAQKRSERYAEFKQAFQKTKRYQRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMY6</accession>
    <name>W6YMY6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peroxidase</fullName>
            <ecNumber evidence="12">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_108220</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="9 12">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="9">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the peroxidase family. Ligninase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="12"/>
    <dbReference type="EMBL" id="KI964148">
        <property type="protein sequence ID" value="EUC40652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692824.1">
        <property type="nucleotide sequence ID" value="XM_007694634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMY6"/>
    <dbReference type="GeneID" id="19119205"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108220"/>
    <dbReference type="eggNOG" id="ENOG502SM0W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041038_1_0_1"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000021">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001621">
        <property type="entry name" value="Ligninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00462">
        <property type="entry name" value="LIGNINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 12 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006994365" description="Peroxidase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="13">
        <location>
            <begin position="144"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="77"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="98"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC40652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="347" mass="37916" checksum="71FE963A06494588" modified="2014-04-16" version="1">MVFKAALTFSLLGLSLFASAGPLQQREALLDILEADLGGSFNEIEQLVQDIIGGGKPATDNNQTPKPSKCDQSKDKCCVWYDVSAELTKLFVGKDKQCNDNARAAVRMGFHDAGSWDQSSSHGGADGSLIMDFGEHDRRENNGLQNVRTLLRGVRDKYKVGAADLVQYAHNHATVSCPKGPRVRTFVGRLDATKANPKGLLPDTHDNPDNLIALFKRKGISERELAALVGAHATARQRFVDTSSAAVNKPLDSTPGVWDVEFYNDTLNNPIGATAEQKVFVLPSDKALSQHPKTSGDWRRFVGNQGGWNADYARAYIKVSLFGVKQEQLAKMVDCTQTLPLSRDIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNK6</accession>
    <name>W6YNK6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_107512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964130">
        <property type="protein sequence ID" value="EUC40937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692552.1">
        <property type="nucleotide sequence ID" value="XM_007694362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNK6"/>
    <dbReference type="GeneID" id="19119063"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107512"/>
    <dbReference type="eggNOG" id="ENOG502TGRN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2722677_0_0_1"/>
    <dbReference type="OrthoDB" id="3943049at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="70" mass="7841" checksum="6401620DF874DB64" modified="2014-04-16" version="1">MSFSWLAPILTPAALRSVEADGRPVITLFLVIFGLSVLGAVIWYVHFVTSKMYPKKKDAKKGKMLGFIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQI3</accession>
    <name>W6YQI3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_10088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964222">
        <property type="protein sequence ID" value="EUC39920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693561.1">
        <property type="nucleotide sequence ID" value="XM_007695371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQI3"/>
    <dbReference type="GeneID" id="19117762"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10088"/>
    <dbReference type="HOGENOM" id="CLU_2236111_0_0_1"/>
    <dbReference type="OrthoDB" id="3261222at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="105" mass="12190" checksum="8E124986EF49833A" modified="2014-04-16" version="1">MAISTPERDRDHEATSLPAELLAPLKRRARNTTEQNEHYRRRPLQLDLSADDSDTIQIESSQPIRQARKSTATNKDLLTALTKIIQQQNETIQNLERETREIRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQR3</accession>
    <name>W6YQR3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kish</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_105289</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in the early part of the secretory pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Golgi apparatus membrane</location>
            <topology evidence="2 9">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the KISH family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964087">
        <property type="protein sequence ID" value="EUC41767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691722.1">
        <property type="nucleotide sequence ID" value="XM_007693532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQR3"/>
    <dbReference type="STRING" id="930090.W6YQR3"/>
    <dbReference type="GeneID" id="19118661"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105289"/>
    <dbReference type="eggNOG" id="KOG3808">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152663_1_0_1"/>
    <dbReference type="OrthoDB" id="10034655at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051523">
        <property type="entry name" value="KISH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009653">
        <property type="entry name" value="Ksh1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13229">
        <property type="entry name" value="PROTEIN KISH-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06842">
        <property type="entry name" value="DUF1242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005151131" description="Protein kish" evidence="9">
        <location>
            <begin position="25"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU910717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC41767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="72" mass="8046" checksum="9208E90764FCA453" modified="2014-04-16" version="1" fragment="single">QTALFNFQSLLLVILLTICTSTYAHSVFPGIIDRNKENWIVSPLWKAARVGERLSPYVSIACVVMATLEFMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQY3</accession>
    <name>W6YQY3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Concanavalin A-like lectin/glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964223">
        <property type="protein sequence ID" value="EUC39918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693567.1">
        <property type="nucleotide sequence ID" value="XM_007695377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQY3"/>
    <dbReference type="STRING" id="930090.W6YQY3"/>
    <dbReference type="GeneID" id="19119557"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110177"/>
    <dbReference type="eggNOG" id="ENOG502SNK4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1224572_0_0_1"/>
    <dbReference type="OrthoDB" id="2862635at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070007">
        <property type="term" value="F:glutamic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13426">
        <property type="entry name" value="Peptidase_G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="entry name" value="Peptidase G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536:SF1">
        <property type="entry name" value="ASPERGILLOPEPSIN, PUTAITVE (AFU_ORTHOLOGUE AFUA_7G01200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889328" description="Concanavalin A-like lectin/glucanase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="23659" checksum="DA9EEC9A6EE8895E" modified="2014-04-16" version="1">MKITTILSATCWLSFVSAAFDYNRGGAVLKAPDGDSFQTVIGTFIVPNLSGSNRLSIWIGIGDGLEQNNILSGGIVYNNTLKTFASYFPDPATDTTSAVPVANGDSITIMVNITLTGGAVTIENKTQNKTTTQNVAAPAGVEIPSFTALAADWFVQGYQVIPGELVATPDFGTVSFTAVKATTKGGTDVPVSRAGRYEIQGTSGQMYSRTTISDAGISVQRQNVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR38</accession>
    <name>W6YR38_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore assembly and biogenesis-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964080">
        <property type="protein sequence ID" value="EUC41917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691551.1">
        <property type="nucleotide sequence ID" value="XM_007693361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR38"/>
    <dbReference type="GeneID" id="19123780"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39953"/>
    <dbReference type="eggNOG" id="ENOG502T2BZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1669046_0_0_1"/>
    <dbReference type="OrthoDB" id="3559694at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024316">
        <property type="entry name" value="APQ12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12716">
        <property type="entry name" value="Apq12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="18121" checksum="B706B8A4D7263EEE" modified="2014-04-16" version="1">MDFVQDYAALLPRLLPPSFADPALHIITTFLGFSRTLSTHLSPLLNKLITQPDVASIVALLFIFFISLKILDMMYRAVVFWINLAFRLAFWGGILIVGLWVWNRGPEGFVDDVSGLIEYWMGEYERYSGEVKMFQQQKEDQIRFKAGQQQKRKGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRX9</accession>
    <name>W6YRX9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_9846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cerato-ulmin hydrophobin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964182">
        <property type="protein sequence ID" value="EUC40248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693235.1">
        <property type="nucleotide sequence ID" value="XM_007695045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRX9"/>
    <dbReference type="STRING" id="930090.W6YRX9"/>
    <dbReference type="GeneID" id="19129270"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9846"/>
    <dbReference type="eggNOG" id="ENOG502SUV9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1283053_0_0_1"/>
    <dbReference type="OrthoDB" id="4500971at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.120.10">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010636">
        <property type="entry name" value="Class_II_hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036686">
        <property type="entry name" value="Class_II_Hydrophobin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341:SF2">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06766">
        <property type="entry name" value="Hydrophobin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101751">
        <property type="entry name" value="Hydrophobin II, HfbII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886034" description="Hydrophobin" evidence="4">
        <location>
            <begin position="20"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="30"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="104"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="20669" checksum="3F284FF48ACC9240" modified="2014-04-16" version="1">MRFTLIHLTSLLALSSAIALPQPQLGGLGGGLLGGGEGGEGGEGGEGGQGGQQGGEGGQGGQQGGEGGLYYGQQGGGQPGGEQQGQQESQYGQQEDQQESQYGQQGGQGEQGGQGQQGGHGQHGGQGQHGHGHGHSQGQGGICGSSSPLCCQVGLLGVTNCASAGAVTTPGAFNAQCAQNGLTAQCCILPLGGLGNLGGDGLVCTALLLLGLGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRY9</accession>
    <name>W6YRY9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_41254</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964168">
        <property type="protein sequence ID" value="EUC40400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693072.1">
        <property type="nucleotide sequence ID" value="XM_007694882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRY9"/>
    <dbReference type="GeneID" id="19124023"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41254"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_2_1"/>
    <dbReference type="OrthoDB" id="3678729at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF164">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="52996" checksum="72319F0387214B9B" modified="2014-04-16" version="1">MAIAVVAAATLGLAFLLYHLCFSLFISPLTKIPVSLNSTSALRIMYGAGSAFERTSFYNIFHAYAKSAMLKGANAAIVEAKIRQYLDLIARQEGSNEIFASLHYFSLDTMTDFLYGKYGKTSCLEGSEADRALVDDIVDVARRRLSWFTVHLPRYTAWLYSWTGLFGKVARGSYPMQLPNTYTGVRRHVMIACQEFARSPAAYDLCESVEQTPPLIAKLWKNHYSRKTGGLDDVDIASGCADHLLAGIDTTSDALMFFIWSLSQPESNRSQQKLVGEVRSISQENLNAHHIPNVEASDKLPYVNAVIKETLRLYAPLPAPEPRKAPTATVIDGYRIPAGTTVSILPYTLYRNLKVFLDIMQFNTDRWMDPSQNTVEISRWFLAFLVEAECALDSKMTRLVAAVYRKYTTTTICDIDIVSPGIISRYEMFYDEGCGGVKVSFGFHYYCTKMKALPSHDISQEHIHFNTLNWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS74</accession>
    <name>W6YS74_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_108716</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="KI964162">
        <property type="protein sequence ID" value="EUC40475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693001.1">
        <property type="nucleotide sequence ID" value="XM_007694811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS74"/>
    <dbReference type="GeneID" id="19119296"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108716"/>
    <dbReference type="eggNOG" id="ENOG502QPXZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_1_1_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF2">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005151096" description="Carboxylic ester hydrolase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="541" mass="59267" checksum="651DEAA68CFFCB13" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS75</accession>
    <name>W6YS75_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_103844</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964066">
        <property type="protein sequence ID" value="EUC42297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691187.1">
        <property type="nucleotide sequence ID" value="XM_007692997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS75"/>
    <dbReference type="GeneID" id="19118385"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103844"/>
    <dbReference type="eggNOG" id="ENOG502SPRN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036934_2_0_1"/>
    <dbReference type="OrthoDB" id="2590011at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="28"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="115"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="322" mass="35807" checksum="9FB84378139DBE38" modified="2014-04-16" version="1">MRKFAFKPFKGDKTAPMDDPTESRNPVQKRREQVRRAQRSHRERKETYIASLESEVVRLRAKEARLESKIKTLYAENSVLKKGLTKQDVPLPTANEATDETISLTVFQENTISKKGSWRKQISVTQPHKPTPNFSQPISPPSSNSSSHSQSSSPTPTPPPTTHLGALDPDIIGMDFVLTLESPCLSHTDISLIPTPHHPRTTSLPTTTGHALTLSACLLHTHPSPPGHRQHSQTPWRAPRSSLSHVLSISSNVPLADGEVTPVQAWEYVRQHATFSGLEVGRWEILKEKLVGAVRCYGYGGVVERKVLENVVFEAFVVGRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTQ1</accession>
    <name>W6YTQ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_40854</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Fung_rhodopsin"/>
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    </dbReference>
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            <end position="32"/>
        </location>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="370" mass="41144" checksum="D3756E09F45530CA" modified="2014-04-16" version="1">MGKPADFADILNGVMWFQVFLATLFIALRLYTRQWIVRNFGWDDILMLVNLATFVGYVACISIGVNYGVGKRTADIIRLDLDYSKAIMWEAIGQGICIMGIAASKGSVALFLLRIVVKQWHVGILWFCIASTTILCVITTALLYAQCIPTAFLWDRTIEGGHCWLNFTPVGLTMGAWSASMDFVLAILPWHVLMGLNMKHKEKITIASGLSLGIFAGACSIVRTIELQSLASMENYVYDTASMLLWSSSEVCMTIVCACIPVLRPLYVRVKYGSRGDSSNKDSYHLKEYSKSKSSRGDGSQPRNKIYMGPGESVLQTTVRMGSDAASEETILRDCNESRYNGSAWDQLSRTKEPKDIHVSTTVTSRDHYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
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            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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            <end position="604"/>
        </location>
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            <end position="40"/>
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            <end position="242"/>
        </location>
    </feature>
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    </feature>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="401"/>
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            <end position="482"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="EMBL" id="EUC41360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="604" mass="68434" checksum="81E07B0B64517FEC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWW0</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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        <property type="term" value="P:mitochondrial translation"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Mitochondrial GTPase 1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GTP-bd"/>
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    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782:SF4">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
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        <location>
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        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="361" mass="40006" checksum="19D3FBE18099F896" modified="2014-04-16" version="1">MSFIPRHAFPPIPSLPRSYFLGHHKSGLQKMKSLLATIDLVIECRDYRVPLTSRNPLFESALEGKERVIVYTKRDLGGGSRDNRNEHVIAQWHHPTPTMFVRNGKDAEGEASGRKSVMKLLDLLREHAQKRWKLVGHRVMVVGMPNVGKSTLLNALRAQGIGKGKVAATGAQPGVTRKVSSSGVKIIPSEDDVESADVGARKKLQGVGGGVYLLDTPGVFIPYVPDAEAMMKLALCGSVKDTIIPPVMLADYLLYHFNLQSPTLYSEYAPPTNEIIELLSEIAKKTGRLGKGGTIDTEATSLWLIQKWRSGSMGRFLLDDINETSLEKAKLDEEGAMPSFNQARKAERERRRERNRARGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX98</accession>
    <name>W6YX98_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_41470</name>
    </gene>
    <organism evidence="5 6">
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964192">
        <property type="protein sequence ID" value="EUC40149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693323.1">
        <property type="nucleotide sequence ID" value="XM_007695133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX98"/>
    <dbReference type="STRING" id="930090.W6YX98"/>
    <dbReference type="GeneID" id="19124065"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41470"/>
    <dbReference type="eggNOG" id="KOG1199">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_42_0_1"/>
    <dbReference type="OrthoDB" id="3819888at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658:SF8">
        <property type="entry name" value="17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="4">
        <location>
            <begin position="6"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="262" mass="27578" checksum="790FE1AE23EC0FBC" modified="2014-04-16" version="1">MKIADRTFVISGGVSGLGLATARALHQQGAYVSLLDLNADNGSKVVSELGSRAKFFETDVSDTQAIAAAVQGTVAWAKETGKHIGGVVAGAGVGMPGLIIDKKNEPLSLESIDFVLNINLRGTLDLIRQTIPHMTTAPSSGPDGARGVIIMIASSAAFDGQMGQVAYAASKGAVASLTLPLARDLSRYGIRAVTIAPSMFDSAMTRMMSDKVRKSLENSMEFPKRPGQPDEFARLVVECIGNDMLNGTVLRLDGAMRMPARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYS9</accession>
    <name>W6YYS9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_97933</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688945.1">
        <property type="nucleotide sequence ID" value="XM_007690755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYS9"/>
    <dbReference type="STRING" id="930090.W6YYS9"/>
    <dbReference type="GeneID" id="19129151"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97933"/>
    <dbReference type="eggNOG" id="KOG4283">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032951_0_0_1"/>
    <dbReference type="OrthoDB" id="361494at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070912">
        <property type="term" value="C:Ddb1-Ckn1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042238">
        <property type="entry name" value="Rad28/ERCC8/Ckn1/ATCSA-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46202:SF1">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="196"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="263"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="397"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="456" mass="49876" checksum="0F09C3F89AEE4A7A" modified="2014-04-16" version="1">MHNQHVLDRAYGFIPNHVLKRACTSRLVYALQPSPSISFSQHLPTPDAPHERIPAHASGISVLTVDKFEGRYLLSAGADSSIALWDLEAQPGATEAGETYTPLTAASKTSEEHKLGITQIHFYPFDSLAFLTSSYDHTVKLYSSETLATSASFDLDSVVYNISLSPVASHLLVACATQNPNVRLVDLRSGATTHSLAGHSGAVLSTAWSPVREHIVVSGATDGTVRFWDVRRSVGELAMLDLEDPVGRRVSQSMSLPRNATVKQAHRGPVNGLVWTEDGRHLVTCGHDARIRVWDTDTGSNTLANFGPMVQNTGLSPRLPVLAPVESVQPGGEVVFYPNGSEVLVYELWEGKLIRRLRRSQQGPHGGLAAGNWQQPAKDRITSLAWRAHEVEMYSGHGDGSISAWKPRTEQDAEADDEEAAEREEREVDKKRKRGVLDEIYQGLIKKPIAFGNMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZL9</accession>
    <name>W6YZL9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Phosphoribosylformylglycinamidine synthase</fullName>
            <ecNumber evidence="4">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Formylglycinamide ribonucleotide amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Formylglycinamide ribotide amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">COCMIDRAFT_37390</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the FGAMS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="4"/>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688676.1">
        <property type="nucleotide sequence ID" value="XM_007690486.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6YZL9"/>
    <dbReference type="GeneID" id="19123238"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37390"/>
    <dbReference type="eggNOG" id="KOG1907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001031_0_2_1"/>
    <dbReference type="OrthoDB" id="6666987at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01740">
        <property type="entry name" value="GATase1_FGAR_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02203">
        <property type="entry name" value="PurL_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02204">
        <property type="entry name" value="PurL_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000002">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000005">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000008">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.650.10:FF:000002">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.650.10:FF:000005">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.750">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00419">
        <property type="entry name" value="PurL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040707">
        <property type="entry name" value="FGAR-AT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055181">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010073">
        <property type="entry name" value="PurL_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01735">
        <property type="entry name" value="FGAM_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003672">
        <property type="entry name" value="PRK05297.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18076">
        <property type="entry name" value="FGAR-AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22689">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13507">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01211">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109736">
        <property type="entry name" value="FGAM synthase PurL, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="PurS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase N-terminal" evidence="20">
        <location>
            <begin position="38"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase linker" evidence="19">
        <location>
            <begin position="193"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="18">
        <location>
            <begin position="459"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="FGAR-AT PurM N-terminal-like" evidence="21">
        <location>
            <begin position="687"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="18">
        <location>
            <begin position="882"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00052585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00057317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00071729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF18076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF22689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EUC44772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1366" mass="149208" checksum="902EB9B7E79EBF07" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z052</accession>
    <name>W6Z052_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Vps52/Sac2 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_30027</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS52 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964117">
        <property type="protein sequence ID" value="EUC41154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692324.1">
        <property type="nucleotide sequence ID" value="XM_007694134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z052"/>
    <dbReference type="STRING" id="930090.W6Z052"/>
    <dbReference type="GeneID" id="19121605"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30027"/>
    <dbReference type="eggNOG" id="KOG1961">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010797_1_0_1"/>
    <dbReference type="OrthoDB" id="19482at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007258">
        <property type="entry name" value="Vps52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048361">
        <property type="entry name" value="Vps52_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048319">
        <property type="entry name" value="Vps52_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190">
        <property type="entry name" value="SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190:SF7">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20655">
        <property type="entry name" value="Vps52_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04129">
        <property type="entry name" value="Vps52_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps52 coiled-coil" evidence="8">
        <location>
            <begin position="163"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Vps52 C-terminal" evidence="9">
        <location>
            <begin position="352"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="182"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC41154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="678" mass="75093" checksum="4412F12D1962EDE4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z091</accession>
    <name>W6Z091_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pathogen-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="319"/>
        </location>
    </feature>
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            <end position="299"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="35327" checksum="BAB93C8FBC445ED6" modified="2014-04-16" version="1">MAAADVEQPPVEEAAPALPDYLTNPNAVLGDEEVKWRYGRAPDYTKTRKVYAETKQKTHEAGSLPQLVENLVKNWEVEASFKPDISDWRTIDPANYSFAINGGKAEGTEAMLEVGTYNAIIAPNEYYSPEYSDFASSHKTFKRMMPTFAWEVLEVYSGPPTVSFRWRHWGIMKNDYVGFNNKGEKVTAKAHGGSIDIQGVTVATVNDKVQLREVRTWFDPMDMFRQIAPHGVVGKENKPDNVSPADALDEAQAGVEVPEEQELPDATVQSKEGFERTTAEIDKKRAEEQRAEDVPDGHVDVSGAQGDVGACPFMSGATH</sequence>
</entry>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
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    </reference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC43340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="407" mass="44733" checksum="93508E6C2714B73F" modified="2014-04-16" version="1">MAKSIHVVSKLDNTKHAVFHIDQDPPSLAASSVRVQTWLVSLTSNNLTYARSGTPLRWWDTYPVPEASPTPFNNREEWGIVPAWGYGRVLESTIDAIAPGSLLWGMWPTSEHAVDLQLEAIEPSGHWSERSTQRSKLMTIYNTYEQVSESNAQTMRMTALCKPLWQGPHLLNTSVFSARRIHPFGFGAPWSQEDADLSSAVVVSLSASSKTGRGFGWEMSRNRDVSKHGPRALIQMTSIPNTLPRYDSPLPMKASPYDGTDAMAWAEQFKPSRVVIVDFGASDAILESVRATASKLAPNITVVAVGYEAKVYTKEEIAARMATANTKVLVNTSGLRDRVIESQGALEFSRELEGTWDRCLKEEAFASLQVKALNAVSGEDGIEGAWSALCDRKVPADVGMVVEFSIS</sequence>
</entry>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689811.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19128647"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95377"/>
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    <dbReference type="OrthoDB" id="2142040at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34706">
        <property type="entry name" value="SLR1338 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34706:SF1">
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    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="357"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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            <end position="54"/>
        </location>
    </feature>
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        </location>
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    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="136"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="375" mass="40520" checksum="EDA77E946F03F69C" modified="2014-04-16" version="1">MAFSLASQYCRTPTNFSDHHSLHLQPQSTLQPGSMLGKVKRAFSTRKSSTSSNDHSARGTAVTGQTQNNTLTAAPVSPKRAGSRNSGLAPPPSSASPFTSPSSATRRPDTDRSLGSTAMNASGSNNEAPPAYTPGPAQNASAFQSPSITTNSDSDPYAFLRSFDTIFLIDDSGSMAGRSWRETQEALATITPICTAHDEDGIDIYFLNHPDSSLYKRITSPSTIIEIFQTVRPGGATPTGQRLHKILKPYLQRYEQDDKTKPINIIVITDGEPSDDVESTIIQAAKKLDKLDAPAWQVGIQFFQVGREPGAREHLKQLDDGLAELAEDDNLRDIVDTVPFSGAEGESLTAAGILKVVMGAVHRRLDRTSKDLHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1P8</accession>
    <name>W6Z1P8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38445</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964023">
        <property type="protein sequence ID" value="EUC43643.1"/>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1P8"/>
    <dbReference type="GeneID" id="19123467"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38445"/>
    <dbReference type="eggNOG" id="ENOG502S606">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041168_0_0_1"/>
    <dbReference type="OrthoDB" id="5364312at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42111">
        <property type="entry name" value="YALI0D23727P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42111:SF1">
        <property type="entry name" value="YALI0D23727P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="381" mass="39423" checksum="B6ABCA5EB30D422C" modified="2014-04-16" version="1">MSATEKAAPVPQKPNPPASATTTLRQTKPADNNNNSSSILGKGKKLLGLGKKKGDEGDWPAMEQTGTTAAAAASTTTTTNKTATTTSAPTLLPSPPMSPPERRASPRGSPRMLPVSASPSRRIRSTSPNLHSPASSLIFERNVQEPEPSVDVPAHIKTEDHIPPALDATSLAITDTQLNPDEVEIVTHSAHQPVAVAVAGSMAESLHSPLMAPEESAASSHVDAGESTAPGYGALDTTDPRRLSFISFADVVQAEHVEHDRQEVLGATSGEALQFMSLSSTANRSPSPVRSIASSPPTTSGAASPKATDLARTRSPGSPTSPIVLGHPTPAFGEELPVQIETMRQALRKTRSGDLGGIGTPSQPVSAVGGEDKAGDKPPFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1Z1</accession>
    <name>W6Z1Z1_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_100110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="16"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="175" mass="19912" checksum="9986B7B079CAD558" modified="2014-04-16" version="1">MDVSSGQEDIQLQRCPHLIIKTDTPKVMCFVPWRILQLAGRGVFATKDIPAQTIIDICPVLILGIDENKKHIENTCLYHYTYNWPQTDAHGDHQVSQAVVFGLGSMFNHSTQEQNVGWMRDLGRKIITYRALRDIAAGEELCISYGSHLTFKDADMLPPAPLEDEIEQLRMIEPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2B4</accession>
    <name>W6Z2B4_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_38281</name>
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    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964018">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2B4"/>
    <dbReference type="GeneID" id="19123436"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38281"/>
    <dbReference type="HOGENOM" id="CLU_1970332_0_0_1"/>
    <dbReference type="OrthoDB" id="3690447at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="103" mass="11197" checksum="062BFD86AA17B52E" modified="2014-04-16" version="1">MILWALLCSSSTPSYSPSCLMYVSQSTAARRAFLELVANDAANAARQSAKPTGTTPVGRVPFCRRCILAAANPAFCCMALAFSRTAKLHELPQSTMRPLFKWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2M1</accession>
    <name>W6Z2M1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_25880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963973">
        <property type="protein sequence ID" value="EUC46002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687458.1">
        <property type="nucleotide sequence ID" value="XM_007689268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2M1"/>
    <dbReference type="STRING" id="930090.W6Z2M1"/>
    <dbReference type="GeneID" id="19120838"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25880"/>
    <dbReference type="eggNOG" id="ENOG502SHU8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071111_1_0_1"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF7">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="63"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="272" mass="30470" checksum="CBDF136CC5D71A99" modified="2014-04-16" version="1">MFSSSNRTRYQEGSFSKHRASKSKSSKKNPSFKDSPRRVEKLAQQAQASSAQPSPTSPSLGSAIVTISVGREQRLFAAHEDVLSHSPWFQSLCSGQFFQTTTNKRIDLPDEEPEVFSSILEYLYKGDYYPRVEYDKKRNSWNLEDAGAGANNPNEAVIQSSVGPILKDTIIYCQADKYGLQELKKLALKKQGLQSGIQCSTILTSARYAYANTPDNDSKLRAHYLALIIRARHTFKRSGTMQNEMESGGKLFFDLFVAMVNHMDDLSGKPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z473</accession>
    <name>W6Z473_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL34m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_97949</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688953.1">
        <property type="nucleotide sequence ID" value="XM_007690763.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19129155"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97949"/>
    <dbReference type="eggNOG" id="ENOG502S8P5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129938_0_0_1"/>
    <dbReference type="OrthoDB" id="431691at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:structural constituent of ribosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3980:FF:000001">
        <property type="entry name" value="Mitochondrial ribosomal protein L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_bL34"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="142" mass="15589" checksum="156D38CF7FB31B45" modified="2014-04-16" version="1">MNAFRCLRVVSTSSCALLRPRTSGTAAVAAAQHLSTPLQARQISLLSPRRPLVPVTYSSPSTLAPPGTSSSLASPETLDLVGRISAHPALGSTQIRCGPRDTYNPSHLVRKRRHGFLSRLRTKKGRKMIMRRLKKGRWNISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4J0</accession>
    <name>W6Z4J0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_92220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686861.1">
        <property type="nucleotide sequence ID" value="XM_007688671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4J0"/>
    <dbReference type="STRING" id="930090.W6Z4J0"/>
    <dbReference type="GeneID" id="19128035"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92220"/>
    <dbReference type="eggNOG" id="KOG4640">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011501_0_0_1"/>
    <dbReference type="OrthoDB" id="2110451at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024789">
        <property type="entry name" value="APC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024790">
        <property type="entry name" value="APC4_long_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260">
        <property type="entry name" value="ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12896">
        <property type="entry name" value="ANAPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="7">
        <location>
            <begin position="30"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4 long" evidence="8">
        <location>
            <begin position="324"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="871"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="883"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC46657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="918" mass="102756" checksum="A51F507C00A896F2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4W0</accession>
    <name>W6Z4W0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_26778</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC45015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688480.1">
        <property type="nucleotide sequence ID" value="XM_007690290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4W0"/>
    <dbReference type="GeneID" id="19120997"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26778"/>
    <dbReference type="HOGENOM" id="CLU_1547266_0_0_1"/>
    <dbReference type="OrthoDB" id="10658986at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="173" mass="18300" checksum="D17DDF2619656CB3" modified="2014-04-16" version="1">MARRAECGTQASVRVGFWCARGGVRVRGWSALVTKKPGLGWACWPRGAQAATKEVALDSLRVPECSTAPSVPSDQPPVAAFAADLARTTSVAGGEGQEAYVGEWRRTATTIAAEERCVRGQVCFGGVSWVKRLARLGRRKRCAVCSAASCSAASGCSAKQTRADQSRAARVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z571</accession>
    <name>W6Z571_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAD-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_35495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686556.1">
        <property type="nucleotide sequence ID" value="XM_007688366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z571"/>
    <dbReference type="STRING" id="930090.W6Z571"/>
    <dbReference type="GeneID" id="19122795"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35495"/>
    <dbReference type="eggNOG" id="KOG2914">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_13_0_1"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901">
        <property type="entry name" value="2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901:SF38">
        <property type="entry name" value="PSEUDOURIDINE-5'-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="31703" checksum="4177BB3EFEF3D4AA" modified="2014-04-16" version="1">MTQALPPVRACIFDVDGTLINSEDIYTTIYNHILREYRRPEYPWAIKATQQSRGSRGTNRLLAWAQVPLSPAEWASKEKAHTHLFKNSETLAGVDHLLRTLKFQTAPPILLSLASSAGREKFALKTSHLPCIGRTFQDSALQVFGDDPEMSDSKKKPEPDIFLLALKRLNATNTAHGDRALEPHECLVFEDSIAGVEAARRAGMRVVWVPHQGLARVCKGREMDVLMGRTEADGQVPDYATPVQGEARGPVVGKDGRLMSEDGVVEMRHSLENFPYRAYGIDLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5I7</accession>
    <name>W6Z5I7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GTP-binding protein Obg/CgtA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_96624</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963992">
        <property type="protein sequence ID" value="EUC45033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688444.1">
        <property type="nucleotide sequence ID" value="XM_007690254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5I7"/>
    <dbReference type="STRING" id="930090.W6Z5I7"/>
    <dbReference type="GeneID" id="19128885"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96624"/>
    <dbReference type="eggNOG" id="KOG1489">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011747_2_6_1"/>
    <dbReference type="OrthoDB" id="347018at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="entry name" value="GTP1/OBG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF31">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="Obg GTP-binding protein N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="5">
        <location>
            <begin position="64"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="292"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="60165" checksum="2AC3193E4BC71603" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5L1</accession>
    <name>W6Z5L1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_102463</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PPP phosphatase family. PP-Z subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="KI964047">
        <property type="protein sequence ID" value="EUC42839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690636.1">
        <property type="nucleotide sequence ID" value="XM_007692446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5L1"/>
    <dbReference type="STRING" id="930090.W6Z5L1"/>
    <dbReference type="GeneID" id="19118084"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102463"/>
    <dbReference type="eggNOG" id="KOG0374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004962_3_1_1"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000006">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF484">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PP-Z1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="322"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="532" mass="58071" checksum="3BEFA1DD5BED9891" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5U2</accession>
    <name>W6Z5U2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_102276</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Inositol polyphosphate kinase"/>
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        <property type="entry name" value="IPK_sf"/>
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        <property type="entry name" value="KINASE"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="5">
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    <feature type="region of interest" description="Disordered" evidence="5">
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    <feature type="region of interest" description="Disordered" evidence="5">
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    <feature type="region of interest" description="Disordered" evidence="5">
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    <feature type="region of interest" description="Disordered" evidence="5">
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    <feature type="region of interest" description="Disordered" evidence="5">
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    <feature type="region of interest" description="Disordered" evidence="5">
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        <location>
            <begin position="1823"/>
            <end position="1861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
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    <feature type="compositionally biased region" description="Basic residues" evidence="5">
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        <location>
            <begin position="1830"/>
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    </feature>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1962" mass="216472" checksum="761E32B4A78992A2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z647</accession>
    <name>W6Z647_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">Probable kinetochore protein NUF2</fullName>
        </recommendedName>
    </protein>
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        <name evidence="18" type="ORF">COCMIDRAFT_26384</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
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    <comment type="function">
        <text evidence="1">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NUF2 family.</text>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:protein-containing complex binding"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0045132">
        <property type="term" value="P:meiotic chromosome segregation"/>
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    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
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        <property type="entry name" value="Kinetochore_Nuf2_N"/>
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        <property type="entry name" value="Nuf2_DHR10-like"/>
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        <property type="entry name" value="Nuf2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650">
        <property type="entry name" value="MEMBRALIN/KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03800">
        <property type="entry name" value="Nuf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18595">
        <property type="entry name" value="Nuf2_DHR10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="13" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Nuf2 N-terminal" evidence="16">
        <location>
            <begin position="25"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Nuf2 DHR10-like" evidence="17">
        <location>
            <begin position="279"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="159"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="320"/>
            <end position="347"/>
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    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="376"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002772"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005498"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017594"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF18595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC45455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="461" mass="53939" checksum="5E450D40D5A70F9F" modified="2014-04-16" version="1">MSYNGRMSMARTTQHNQRAPPVNEHDAFMTLPDNEIAGCISDIGIQFTVSDLQKPNPQIIQKVFEWLAELLMNTTREVVAPAMRAAAEDMCGGDAERLYTSDTRDLMGFFVILRKLLRECGIHDFTFNDLYKPTHGRLVKIFSYMINFIRFRESQTEIIDEHFNKAERTKLRIEQLYNDKQTKEMQLADLERNRAATQRLMQEKEKRNNELKTRLLELKRGQEAVAEKLERAKMEQDRLKKLLQQKVENKENVQREVLKLKPYTQQSPTALEDSLRDLSDRLTGDKTQIDMLDRRARALQTSTDSFAVVATDVTSCTRLLTDVQADLAREEEELAKASRHRDALADRSNNVRDVERQERLLQKQLGNINARTDKLKAKGDEEAERARRRMEELRDTHAKLTEERGEKGREMERRRVRIEQTEKKMAELKDNIENEVHSAHDEYLKMESHIKLYITEMEQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z697</accession>
    <name>W6Z697_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_5423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963986">
        <property type="protein sequence ID" value="EUC45318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688115.1">
        <property type="nucleotide sequence ID" value="XM_007689925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z697"/>
    <dbReference type="GeneID" id="19124612"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5423"/>
    <dbReference type="HOGENOM" id="CLU_1686252_0_0_1"/>
    <dbReference type="OrthoDB" id="3692447at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886515" description="AA1-like domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17102" checksum="58440794DDD767D8" modified="2014-04-16" version="1">MRLTIPLFTLAACASAVAVPNPEVVAERGNPVAFWDFDFVRAYFTGGFVETVSAVFTSDKYPEGFKSFCKTTHYDGARFVPSCTPDHFHYHYDLSASNKSFLFLSVTVQQRVSQPHELIIKGESGFSPNHVDNTLVGSVHIPVTAQEPAPYKAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6M8</accession>
    <name>W6Z6M8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-ornithine N(5)-oxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963983">
        <property type="protein sequence ID" value="EUC45473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687988.1">
        <property type="nucleotide sequence ID" value="XM_007689798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6M8"/>
    <dbReference type="STRING" id="930090.W6Z6M8"/>
    <dbReference type="GeneID" id="19128639"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95352"/>
    <dbReference type="eggNOG" id="ENOG502QRUQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026100_0_0_1"/>
    <dbReference type="OrthoDB" id="412005at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029731">
        <property type="entry name" value="OSGIN1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15192:SF8">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15192">
        <property type="entry name" value="PROTEIN CBG05349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="487"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="60273" checksum="1533FED060238618" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6T5</accession>
    <name>W6Z6T5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_101352</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964035">
        <property type="protein sequence ID" value="EUC43254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690235.1">
        <property type="nucleotide sequence ID" value="XM_007692045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6T5"/>
    <dbReference type="STRING" id="930090.W6Z6T5"/>
    <dbReference type="GeneID" id="19117860"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101352"/>
    <dbReference type="eggNOG" id="KOG0805">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_6_2_1"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07564">
        <property type="entry name" value="nitrilases_CHs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044149">
        <property type="entry name" value="Nitrilases_CHs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044:SF2">
        <property type="entry name" value="CN HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044">
        <property type="entry name" value="NITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="352" mass="38790" checksum="992E011FF2FDE8A8" modified="2014-04-16" version="1">MASILRVAACHASPAFLNARRTTDKAIALVKQAASNKANLVVFPETYISAFPIWSSLRPPTDNHWLFQRMVQESVYADGDEMEAVREAARSSGVLVSIGFSEKSRHSNGCLYNSNLIIGTEGEVLVHHRKLVPTFFEKLTWSPGDGHGLRVASTQFGRIGTLICGENTNALARYSMIAQAEQVHISTWPAIWPTRTLQKIPPSAENGVHQASTRGANYDNLAANRTRAAAHCFEAKCFGVACSGYLGEDAFEAIVDGASQPDVVTETLRAMPRAATFFLDPTGAPLPSFIYKDSQKQDMDALQSDEDILYADMQLEDCIEGKQYHDVVGGYQRLDIFDLKVDRSRKDPVKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z715</accession>
    <name>W6Z715_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964032">
        <property type="protein sequence ID" value="EUC43344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690135.1">
        <property type="nucleotide sequence ID" value="XM_007691945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z715"/>
    <dbReference type="GeneID" id="19121259"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28181"/>
    <dbReference type="HOGENOM" id="CLU_1030525_0_0_1"/>
    <dbReference type="OrthoDB" id="10578211at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="270" mass="29796" checksum="1AEE53EB1B9DBABC" modified="2014-04-16" version="1">MSRFGDRDFPNLTALESRRLATSAKDGNHGQGEAMESVMEPEDKRVIRQRSQAWQGMHGLHRIGISWALTSGWAMDGVESVDRRPDLWDAAAEAGRWPVISEDRGMMPQMVSRASEKQAEGAGTPRRTGKPVPVQATRRRLSQTLVEAPSAAMSANERGGVRRRNGEGVSDSGTGGGGMDGRMDRWMCQGPQCSGQKQYNAAPGPTRHWAAGMSIGPASWQSLLWELTYISRPWRCFVQLSASPKPARHTHTQTSPFPIRVFLPHSEHEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z731</accession>
    <name>W6Z731_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Maltase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_36489</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687664.1">
        <property type="nucleotide sequence ID" value="XM_007689474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z731"/>
    <dbReference type="STRING" id="930090.W6Z731"/>
    <dbReference type="GeneID" id="19123043"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36489"/>
    <dbReference type="eggNOG" id="KOG1065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_11_0_1"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000001">
        <property type="entry name" value="Maltase-glucoamylase, intestinal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000138">
        <property type="entry name" value="Putative alpha-glucosidase AgdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030459">
        <property type="entry name" value="Glyco_hydro_31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00707">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="12">
        <location>
            <begin position="227"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="11">
        <location>
            <begin position="383"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="13">
        <location>
            <begin position="825"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="610"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="610"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC45785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1047" mass="116045" checksum="74D59C9E16319D9B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z735</accession>
    <name>W6Z735_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_89743</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA43 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685945.1">
        <property type="nucleotide sequence ID" value="XM_007687755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z735"/>
    <dbReference type="STRING" id="930090.W6Z735"/>
    <dbReference type="GeneID" id="19127538"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89743"/>
    <dbReference type="eggNOG" id="KOG4134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1030528_0_0_1"/>
    <dbReference type="OrthoDB" id="10250504at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000004">
        <property type="entry name" value="RNA polymerase I subunit Rpa43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041178">
        <property type="entry name" value="RPA43_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17875">
        <property type="entry name" value="RPA43_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="9">
        <location>
            <begin position="19"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="RPA43 OB" evidence="10">
        <location>
            <begin position="119"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="227"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="270" mass="29714" checksum="4767625CA5D10731" modified="2014-04-16" version="1">MAPVPSESVSLFHTERISQYVSIPPSCLSDPFSAVCATVLSPLLLTYFPPANGVVLAYEDVELSSTPPTASATKSYSKHAQNDSERKNGSHAEPLLLKHVDEYAAPFLWATASFLVWRPAQNAYLQAHITDHAKTHITLAHLNTFPVSILKENMPADWSWHQNESGKVKKGWDDKLSDEGGWWVDGKGKKVEGELRVRIRNIDGRMDGKGKGKGFLRIDGSLLSQEEEKAAKAAQKAGRGGKKTTTDAARTQQRREQTNGDVMEVDSESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7F2</accession>
    <name>W6Z7F2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_111023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KI964300">
        <property type="protein sequence ID" value="EUC39626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693854.1">
        <property type="nucleotide sequence ID" value="XM_007695664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7F2"/>
    <dbReference type="ESTHER" id="cocmi-w6z7f2">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="19119704"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111023"/>
    <dbReference type="eggNOG" id="KOG4389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_15_2_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012226755" description="Carboxylic ester hydrolase" evidence="4">
        <location>
            <begin position="16"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="26"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC39626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="518" mass="56888" checksum="49E821E59DCDABD5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7G3</accession>
    <name>W6Z7G3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_25920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687502.1">
        <property type="nucleotide sequence ID" value="XM_007689312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7G3"/>
    <dbReference type="GeneID" id="19120848"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25920"/>
    <dbReference type="HOGENOM" id="CLU_2084439_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="10"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="117" mass="12578" checksum="B9C4E1FAB0A93177" modified="2014-04-16" version="1">MAHSPVRLHAIATITRTTSEQDHGPAEEESNALGNEGLDLCLLGLADLSEDPVAKQYQRFRPHDGVSKLTTTGVPPFRGVPTVRLAMAKKRGECSNRQTVSIFLGGKDQGKVLGKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7V0</accession>
    <name>W6Z7V0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964260">
        <property type="protein sequence ID" value="EUC39756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693728.1">
        <property type="nucleotide sequence ID" value="XM_007695538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7V0"/>
    <dbReference type="GeneID" id="19119637"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110681"/>
    <dbReference type="HOGENOM" id="CLU_2339057_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="98" mass="11039" checksum="50F6F925D10A53FB" modified="2014-04-16" version="1" fragment="single">ISKRLTAVKGLDRFCASTVSGTTRRLAEHLFVILALHPKIKFRNSHSVGALNEINVLYCDITALLDKSFLNDKETHPERRIHRAHLVIKHCSLALKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z842</accession>
    <name>W6Z842_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-sulfurylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Sulfate adenylate transferase</fullName>
            <shortName evidence="9">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MET3</name>
        <name evidence="13" type="ORF">COCMIDRAFT_34634</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>sulfate + ATP + H(+) = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9">Homohexamer. Dimer of trimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the APS kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="9"/>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685584.1">
        <property type="nucleotide sequence ID" value="XM_007687394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z842"/>
    <dbReference type="STRING" id="930090.W6Z842"/>
    <dbReference type="GeneID" id="19122601"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34634"/>
    <dbReference type="eggNOG" id="KOG0636">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022950_0_0_1"/>
    <dbReference type="OrthoDB" id="468at2759"/>
    <dbReference type="UniPathway" id="UPA00097"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010134">
        <property type="term" value="P:sulfate assimilation via adenylyl sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.400.10:FF:000003">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000802">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000052">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.10">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03106">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027535">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050512">
        <property type="entry name" value="Sulf_AdTrans/APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004040">
        <property type="entry name" value="PRK05537.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700:SF1">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-sulfurylase PUA-like" evidence="12">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Sulphate adenylyltransferase catalytic" evidence="11">
        <location>
            <begin position="176"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="APS kinase" evidence="10">
        <location>
            <begin position="397"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric regulation domain; adenylyl-sulfate kinase-like" evidence="9">
        <location>
            <begin position="397"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="199"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="293"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="436"/>
            <end position="439"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
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            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="site" description="Induces change in substrate recognition on ATP binding" evidence="9">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00062002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC47897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="575" mass="64363" checksum="35AC0C532E69F79E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z868</accession>
    <name>W6Z868_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_38349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964020">
        <property type="protein sequence ID" value="EUC43759.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691542.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="113" mass="13045" checksum="1B4ADE1F6A5333C9" modified="2014-04-16" version="1">MKRTPNPRRVHVSSSNFRQLVRHTACYVRVPYAGHHNQDDASRSVVRLGRFGRLDSASFTLQHEVVAAETLRHQRLHQRMDAQGENTVHDCGALRNSHETWTHRQRSPRADVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z887</accession>
    <name>W6Z887_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_110182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
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            <dbReference type="EMBL" id="EUC44159.1"/>
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        <source>
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    </evidence>
    <sequence length="565" mass="59076" checksum="37C3780C53C574E0" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688668.1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="73"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="103" mass="11854" checksum="80337772AA0AB4B7" modified="2014-04-16" version="1">MTTSAVKKKWVHCCTVSVSWLGRTWKKSKADTCAAVAVRGAKLACAYVEPWFVQLHACIWYRYRAGRRVYLRRKQKSKKRGDDDWCDAGRDGEANDGAVERRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA33</accession>
    <name>W6ZA33_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_35565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686633.1">
        <property type="nucleotide sequence ID" value="XM_007688443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA33"/>
    <dbReference type="GeneID" id="19122813"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35565"/>
    <dbReference type="eggNOG" id="ENOG502SEV8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104756_1_0_1"/>
    <dbReference type="OrthoDB" id="2507140at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886796" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="16693" checksum="C3E5834BE69ECA64" modified="2014-04-16" version="1">MRFSTAVAVALSASVSLVAAQDKCDAQNIVDTCVSGYQSRIDACNKKGNDFICLCDVYRDVLVCYNNCPDSLDRPPVENTVTSYCNAAEPLRAAASSSMASVASVAATQSHASATKTSEPTATGSGTSAGSSTSPTAPAFSGASGADKNSIKAGAALLALVGAAGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAE2</accession>
    <name>W6ZAE2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA (guanine(37)-N1)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA methyltransferase 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TRM5</name>
        <name evidence="12" type="ORF">COCMIDRAFT_23478</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion matrix</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Predominantly in the mitochondria and in the nucleus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRM5 / TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="10"/>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684699.1">
        <property type="nucleotide sequence ID" value="XM_007686509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAE2"/>
    <dbReference type="STRING" id="930090.W6ZAE2"/>
    <dbReference type="GeneID" id="19120442"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23478"/>
    <dbReference type="eggNOG" id="KOG2078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022610_2_2_1"/>
    <dbReference type="OrthoDB" id="408788at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070901">
        <property type="term" value="P:mitochondrial tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.110:FF:000001">
        <property type="entry name" value="tRNA (guanine(37)-N1)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF36">
        <property type="entry name" value="TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="11">
        <location>
            <begin position="148"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="277"/>
            <end position="278"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="305"/>
            <end position="306"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC48702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="473" mass="53812" checksum="8B9BA6D13E69AC66" modified="2014-04-16" version="1">MSLQEATDDMFAPPVNRAMKVLDRSFFQKTIPTSAARIFNPKDISRCRKELTAAKDTLPNNRVDPIRADPDVDKAQKGVKCLLLRPEVIHTDRTTWSPKLRDLEQDGTLGVIPYQLHLDYDYFTYSEITGAIIPPPESKHDDEIPQGFALAGHVAHLNLRERYWPYKYLIAAVLADKNPMVKTVINKLDNVGTENAFRTFQYEVLYGPDDMNVELREQGCTFKFDFAKVYWNTRLHTEHERLCNLFKEGEAICDVMAGVGPFAIPSGKKKCFVWANDLNPESYNSLVNNIKINKVGDFVRPFNIDGGAFIRQASAHLLVLDPRHTIPIYPKTKFSRSNPQENKQPEPIKTLVRPRFFAHYVMNLPASAITFLPSFIGLYANIPGLPAADIKKMLAPHTEQKLPMIHVHCFSTKSDDNVAEIKGICEEISRQIEYEITPGMADVYVHDVRDVAPKKRMFCASFRLPEDVAFRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAV1</accession>
    <name>W6ZAV1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_71526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964135">
        <property type="protein sequence ID" value="EUC40851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAV1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_71526"/>
    <dbReference type="eggNOG" id="ENOG502RFQ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_871550_0_0_1"/>
    <dbReference type="OrthoDB" id="5372859at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="313" mass="35677" checksum="9E3C401CFF3994B3" modified="2014-04-16" version="1" fragment="single">PVYRNFLVSPRIPPEIVLQTIQHIPFSNGALISALRNAHPRLRALFSTYEQSLTRQFMQTELRHAERDFPCEQGAFSLTWLASCVRTYDIIDDIMDALCSPHNFTAITPHNVFLGYTGFLLLHRISLLEKTGGDAQRYIESLQKDALTAIYLSLHHSTLAARYHGSGWINQRTYGVSMSSEHLSLRNELEFCFAEAALSEGPEFVSDTLLLHRERSDCEVVLLNFYHEYGVRGWEGPCEGAKGGFEPPRTQGPRREGDRKSLWVTVLKCLAGWMRCEVGSVRERVERELESTEHRLANLTLGGKEWLLRGRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC27</accession>
    <name>W6ZC27_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Clp R domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_3481</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685899.1">
        <property type="nucleotide sequence ID" value="XM_007687709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC27"/>
    <dbReference type="STRING" id="930090.W6ZC27"/>
    <dbReference type="GeneID" id="19122647"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3481"/>
    <dbReference type="eggNOG" id="KOG1051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_0_1"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000120">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF176">
        <property type="entry name" value="HEAT SHOCK PROTEIN 78, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="49"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="450"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="10">
        <location>
            <begin position="627"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="262"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="722" mass="80276" checksum="7CB8272F006B1AEA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC88</accession>
    <name>W6ZC88_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_90382</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686121.1">
        <property type="nucleotide sequence ID" value="XM_007687931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC88"/>
    <dbReference type="GeneID" id="19127672"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90382"/>
    <dbReference type="eggNOG" id="ENOG502S3HY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_25_0_1"/>
    <dbReference type="OrthoDB" id="5401779at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="47"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC47413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="406" mass="45849" checksum="9B70DE817012C097" modified="2014-04-16" version="1">MTSRFPTAEEFASFPPPNYVNPTNHLPMALGVVIPMSVLVTVFMSCRLYCRTVLVKTLGWDDGLMSIAALLCIGSNIMLIISMLPEYQMGYHLWDIHPEKLYGSMKAAQMGMATQLLFTAITTFMKVAILLTYIRIFPAKLDRWFCHLMIFYTVTLNTACFFVTLFQCSPASTYWKVFEFIGTAKCLNIKVIYYFHGGQNTLSDFIVFLWPARNLINVQVSQRQRFTLIMMFSLGVIVCIAGIVRLYFTYRYLVSFDAFWYGGSVFIIMSIESAVGVACGCLPGCKPLMNKMFPRIFASSSQSSYPRRSAHLRAHKGIQESFSGARSAQASYNQKEDNPNVMEKAMRRDTPSSHEVVVSPSKPHPQHPGLRPPSRAAFPGGRREGYSELDNGSDDSIEMFLLLQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC96</accession>
    <name>W6ZC96_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DHHA2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_3385</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685807.1">
        <property type="nucleotide sequence ID" value="XM_007687617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC96"/>
    <dbReference type="STRING" id="930090.W6ZC96"/>
    <dbReference type="GeneID" id="19122420"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3385"/>
    <dbReference type="eggNOG" id="KOG4129">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019358_5_0_1"/>
    <dbReference type="OrthoDB" id="374045at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.20:FF:000008">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="entry name" value="DHHA2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF20">
        <property type="entry name" value="EXOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887363" description="DHHA2 domain-containing protein" evidence="5">
        <location>
            <begin position="20"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="DDH" evidence="6">
        <location>
            <begin position="66"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA2" evidence="7">
        <location>
            <begin position="275"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="50584" checksum="3F62D2235CC03585" modified="2014-04-16" version="1">MKPIHALLPGLMAVSHVAAAPQQAVLDALSKPSTKPVGVGHFSEWSRQTKKEFLIDWQAGKESEWILVQGNEGGDMDSMTAALTWAYHLEHATMNTSNPLKAIALLQTPSHALDLRPENKLALDNSQMTPGHEDLLTLDELPEDPETLSTKLKGIVLVDHSEPLKKWSAAKILSIFDHHKDRGTAPDADPRVFETAASCTTLVARQMLDELEKLDEEYHMPHELLELILSAIAIDSGGLTGDKTTKADIEISKRILARSNWRDDDLKDVMEDLDDELTKAQKDIDNLGLYDLLRRDWKSDAIDTPSPRTPAISVGFASIPYSMDEQILKTEFQELFDWFAIHAAWTAQANVDVSVSINKYKKHYKDGSKEKIREIVLVVRDDVRIDQDQANSLFELVKDAIENNNEGVDFQPWHRADELAPRQMVWQHRSDAGRKVIKPLVEEAIMEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCY3</accession>
    <name>W6ZCY3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_89143</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685719.1">
        <property type="nucleotide sequence ID" value="XM_007687529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCY3"/>
    <dbReference type="GeneID" id="19127414"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89143"/>
    <dbReference type="eggNOG" id="KOG1382">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020880_2_1_1"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:inositol hexakisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000147">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF43">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="554" mass="61709" checksum="D7A9B0E7AB3E2A31" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDS0</accession>
    <name>W6ZDS0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_83297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683592.1">
        <property type="nucleotide sequence ID" value="XM_007685402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDS0"/>
    <dbReference type="STRING" id="930090.W6ZDS0"/>
    <dbReference type="GeneID" id="19126226"/>
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</entry>
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            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            <strain evidence="18 19">ATCC 44560</strain>
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            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
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        <text evidence="3">Protein modification; protein ubiquitination.</text>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE14</accession>
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685199.1">
        <property type="nucleotide sequence ID" value="XM_007687009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE14"/>
    <dbReference type="STRING" id="930090.W6ZE14"/>
    <dbReference type="GeneID" id="19121307"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2843"/>
    <dbReference type="eggNOG" id="ENOG502QQGC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010748_0_0_1"/>
    <dbReference type="OrthoDB" id="65716at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000002">
        <property type="entry name" value="Zn cluster transcription factor Rds2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056751">
        <property type="entry name" value="PAS_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053045">
        <property type="entry name" value="Zinc_cluster_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31986">
        <property type="entry name" value="REGULATOR OF DRUG SENSITIVITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31986:SF7">
        <property type="entry name" value="REGULATOR OF DRUG SENSITIVITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24990">
        <property type="entry name" value="PAS_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="50"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="84"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="243"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="509" mass="56157" checksum="AE330FC27A73DD89" modified="2014-04-16" version="1">MTEHGEADKANVASEPNAPKSASPSKTKTNATGSEAPAKTSKKRRKVNHACIYCRRSHMTCDLERPCTRCVKRNIGHLCRDEPREGVKKAKSEPDNGEGQSQPPQIEPATSEAAPAAALQQPTAPDAGLNLAPHQLPPNGDASTASGTQPDPVPAPQPPALTASNQSFGNYDDMLSSSQNNFQDMHFHPSYMFNTSEVSNEYNLLNDFLNNSLMDDGAFYGGNDFHSLFSDASLMNPMGSLNSNSAFNPNGSRQQQLLPPPAQNAAANTAQRSAGGVPIDKARERYLITAADPAGSDSPEERMNKLLKAKVDAGLLKPFNYVKGYARLNQYMEQNLQQISRVRVLRQLDRFRPKFRERMQSLTDVDLVRIEMWFDKSLMEYDRVFASMAIPACCWRRTGEIYRGNKEMARLIHVPMSKLRDGNIALHEIIAEPSLVSYWEKFGAIAFDHTQKAILTSCSLKNPDPNSKDPEIRCCFSFTVKRDAWNIPALIVGNFLPITEATSGPLPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE36</accession>
    <name>W6ZE36_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming)</fullName>
            <ecNumber evidence="3">1.1.1.179</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">D-xylose-NADP dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_26095</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22000"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15867"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.179" evidence="3"/>
    <dbReference type="EMBL" id="KI963978">
        <property type="protein sequence ID" value="EUC45734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687717.1">
        <property type="nucleotide sequence ID" value="XM_007689527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE36"/>
    <dbReference type="STRING" id="930090.W6ZE36"/>
    <dbReference type="GeneID" id="19120876"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26095"/>
    <dbReference type="eggNOG" id="KOG2741">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_7_2_1"/>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047837">
        <property type="term" value="F:D-xylose 1-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF115">
        <property type="entry name" value="DIHYDRODIOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G07520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="35"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="7">
        <location>
            <begin position="149"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="400" mass="43653" checksum="F803B7571A8DA30E" modified="2014-04-16" version="1">MASPKTVRWGILATGGIALTFTKDLLCDPTTRGVNHLKHTVVAAASSTSESRAKDFLKEVGAPSDAKAYGSYDEFVKNPDIDVVYIATPHSHHYQNAMLCLEAGKNVLCEKAFTVNAAQARKLAEVARSKNLFLMEAVWTRYFPLSIYVRDQITSGRIGPVARVLSDNSMALDPEKSFADGKNRMVNPDLAGGALLDLGIYSLTWVFQTIYHTQSEKTRQAPQIQAFVKNYEPTGMADEHSTVILRFPRSKEEGGEAHAVATTSLRVATSPGGNMDAPFVRIQGPLGEIQVFGSSFRPRSIKIITNDGKVESKEFPIPGPGKGSGWYNGFGGSLQPEGEGQGMFWEADEAADAIINGRKEGRFLGLDESVLIMEAMDEVRKQGGLVYPDKIETLDYPTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEC4</accession>
    <name>W6ZEC4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_2807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC48370.1"/>
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        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="53"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="291" mass="33449" checksum="610FECAC01B4E6D2" modified="2014-04-16" version="1">MSCSYWESTQRKFWTFTKQDLALERKRMEDAERNLVNLYPLPDRRHLSIYFSHQLSKMARPLGVRQQALATAQVYVRRFYTKVEIRRTNPALVLATALYLACKMEECPQHIRMVLAEARHCWDTSFNDISKIGECEFSLISEMNSQLILHHPYRSLAELQTQFQLTQEENALAWSIINDHYLTDLPLLHAPHVIAITAMFLAVVLKPIGSQVNAVGMNNALQTLGNARGGQGMQARIQKLVDWLAESNVDIEAVVECTQELISLYEVWESYTDKTCKDQIAKFVKARGLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEQ8</accession>
    <name>W6ZEQ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-methylcrotonyl-CoA carboxylase 2</fullName>
            <ecNumber evidence="4">3.2.1.101</ecNumber>
            <ecNumber evidence="6">6.4.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_87561</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13589"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57344"/>
            <dbReference type="ChEBI" id="CHEBI:57346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AccD/PCCB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="4"/>
    <dbReference type="EC" id="6.4.1.4" evidence="6"/>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685186.1">
        <property type="nucleotide sequence ID" value="XM_007686996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEQ8"/>
    <dbReference type="STRING" id="930090.W6ZEQ8"/>
    <dbReference type="GeneID" id="19127093"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87561"/>
    <dbReference type="eggNOG" id="KOG0540">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011147_0_0_1"/>
    <dbReference type="OrthoDB" id="439921at2759"/>
    <dbReference type="UniPathway" id="UPA00363">
        <property type="reaction ID" value="UER00861"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905202">
        <property type="term" value="C:methylcrotonoyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004485">
        <property type="term" value="F:methylcrotonoyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000033">
        <property type="entry name" value="Mannan endo-1,6-alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000004">
        <property type="entry name" value="Methylcrotonoyl-CoA carboxylase beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000007">
        <property type="entry name" value="Methylcrotonoyl-CoA carboxylase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855:SF13">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1002"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="12">
        <location>
            <begin position="90"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="13">
        <location>
            <begin position="355"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="965"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC48353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1024" mass="111128" checksum="77831BA45E5B8DE4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFA0</accession>
    <name>W6ZFA0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase family 34 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_33766</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684714.1">
        <property type="nucleotide sequence ID" value="XM_007686524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFA0"/>
    <dbReference type="GeneID" id="19122400"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33766"/>
    <dbReference type="eggNOG" id="ENOG502SHP1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039079_3_0_1"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000237">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF8">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 34 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="320" mass="37601" checksum="69097FEDE0EAF5CD" modified="2014-04-16" version="1">MSFDPRISFFAHGDSKCLPEVSPEFIQAATFKRAKCRKYSPFASERSRIGIVTAHFGEGKEHYQMAFQTHLFHSLVHGTEVRVMCDPIVDDLWNKPAYILDLLFREMMKPEKERLEWIQWVDRDTLILDQCRPISSFLPPEKGRRGSWWRRNDGQKEEQQGQANTTHLLVTEDWNGLNNGVFLLRVNSWAIELFTAILAFRHYRPEVDLPFTEQSAMEQVLRTEQFRDKTRYVPQHWFNAYEGGAAQLFEDREDEEGLKQFQARRGDYLVHFAGHNRKDQAIRDWKSMLDQSGDVWEGHRVQRDVSPEIETFWKGLGYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFR5</accession>
    <name>W6ZFR5_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964064">
        <property type="protein sequence ID" value="EUC42346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691131.1">
        <property type="nucleotide sequence ID" value="XM_007692941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFR5"/>
    <dbReference type="GeneID" id="19118370"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103748"/>
    <dbReference type="eggNOG" id="ENOG502TASV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_739675_0_0_1"/>
    <dbReference type="OrthoDB" id="3886371at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="387" mass="43623" checksum="98DFCC4B26EF366A" modified="2014-04-16" version="1">MSPYQHLFSTNAVLGVWRNLRNTKDNNDLLLTLQYHQEDLQRQKGNKYTKGGISESAQEVSDGKTVDVGGKSISFVVPWRAMQNQRRELKEKEKELAEALIRHLAAGLSRQMSKIEFQMNDNAPFANGKNLYTGGEIAQKFLPPVQALFEQKPVPQRIIFELLMELKDLVYMAMAGCSKEVLEHEIGSTGTASLEELDDAIVRAITPPPPFLESHHHKDLEQGHKRSLRRKASSLLSKHPKQDQQAVSFLLSAPEELIYTLESLETTALAFTQLPLPLLDFCAHAVITLRRLIPRPLLSDLSQQKKKKIRQNCAEYARCSKWAGAQWRQNGGCGRDCKNEDEDPEGLPSWHRCSRWFDEKGGGTYMVGGGRAVEREDGFGVVRMTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFU7</accession>
    <name>W6ZFU7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EDC4-like protein pdc1 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_2174</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat EDC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684476.1">
        <property type="nucleotide sequence ID" value="XM_007686286.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZFU7"/>
    <dbReference type="GeneID" id="19120114"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2174"/>
    <dbReference type="eggNOG" id="ENOG502R9YM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003635_0_0_1"/>
    <dbReference type="OrthoDB" id="21128at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000817">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055393">
        <property type="entry name" value="Beta-prop_EDC4L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045152">
        <property type="entry name" value="EDC4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598:SF5">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24106">
        <property type="entry name" value="Beta-prop_EDC4L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EDC4-like protein pdc1 beta-propeller" evidence="7">
        <location>
            <begin position="433"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="539"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="889"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="958"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1285"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="889"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="912"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC48905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1455" mass="158593" checksum="22E1E598B6D46323" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG90</accession>
    <name>W6ZG90_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_85695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684440.1">
        <property type="nucleotide sequence ID" value="XM_007686250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG90"/>
    <dbReference type="GeneID" id="19126712"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85695"/>
    <dbReference type="eggNOG" id="ENOG502SCZX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_509108_0_0_1"/>
    <dbReference type="OrthoDB" id="5377009at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="314"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="494"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="528" mass="57514" checksum="A41297F5EB2A3EDA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHA6</accession>
    <name>W6ZHA6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF962-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_91960</name>
    </gene>
    <organism evidence="3 4">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="201" mass="21599" checksum="4DC17C7C572B1D42" modified="2014-04-16" version="1">MSSTRKFATVEIGAKDDMANDNTTNSAPANNTSVPAPPTLVTTSNDDMTLSDVNIASNTPRLAPPLHTPSTPGHFINQEPNPTSLCSSPTLVSSIFPTELPLRTPPRPSLISRVFSLSPPSAHAARAGNREPRTFHTTDIEMGGQEHLNRVLQQGERAKNTKKIEKVKFVLLLMGGTALCLAMGIMVYLVVKFAAEDDDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHR9</accession>
    <name>W6ZHR9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">General stress protein FMN-binding split barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_84378</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684036.1">
        <property type="nucleotide sequence ID" value="XM_007685846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHR9"/>
    <dbReference type="STRING" id="930090.W6ZHR9"/>
    <dbReference type="GeneID" id="19126455"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84378"/>
    <dbReference type="eggNOG" id="ENOG502RZBA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091428_0_0_1"/>
    <dbReference type="OrthoDB" id="434253at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052917">
        <property type="entry name" value="Stress-Dev_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038725">
        <property type="entry name" value="YdaG_split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34818">
        <property type="entry name" value="PROTEIN BLI-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34818:SF1">
        <property type="entry name" value="PROTEIN BLI-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16242">
        <property type="entry name" value="Pyrid_ox_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="General stress protein FMN-binding split barrel" evidence="2">
        <location>
            <begin position="29"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="204" mass="22195" checksum="BEE4378FF2CEF3C7" modified="2014-04-16" version="1">MSGFSNTDTGSKTADPYTQKNLEEPSLKEKVEDLFSFVDKTKFCLLTTQVADSDLLASRAMALAAKEGHGFDLLFHTNTESGKTDDLKEHASVNIGFINNSGEWASISGHATIETDREVVRKHYSPALKAWIGDLGDGKHDGGPEDPRIGIIRVKASTAQYAISKRTQIGGLVELAKGIATGESPNVNKLRQISEAEIQQYRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHT2</accession>
    <name>W6ZHT2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Amine oxidase</fullName>
            <ecNumber evidence="11">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_1598</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="11">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="10">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10 11">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="11"/>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683825.1">
        <property type="nucleotide sequence ID" value="XM_007685635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHT2"/>
    <dbReference type="STRING" id="930090.W6ZHT2"/>
    <dbReference type="GeneID" id="19119902"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1598"/>
    <dbReference type="eggNOG" id="KOG1186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011500_3_1_1"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000001">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF33">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="14">
        <location>
            <begin position="13"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="13">
        <location>
            <begin position="244"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="656"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="656"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="9">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="10">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC49550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="688" mass="76684" checksum="1FABA974203CAA18" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI09</accession>
    <name>W6ZI09_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cation efflux protein cytoplasmic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_84041</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963930">
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        <source>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
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    <sequence length="372" mass="40604" checksum="80FCE80BDF1BC243" modified="2014-04-16" version="1">MPSITRKTRLRAVIAISFCFFLAEISVGFYTRSLALVADAFHYLNDLIGFIIALVAVQVSERKTSPADLSFGWARAQLLGAFFNGAFLLALALSIALQSIERFITIEHVDNPKLILIVGCIGLFLNIISVLFLHEHDHGHGHSHGHGNSSDREVRLSTPTHANHLHLAMQPKKHGMDLGIFAVLLHVIGDAINNIGVIISAVIIWFVKSPNRFYADPAVSMWIAIMIFLSALPLTKRSGKILLQSAPLGVKIEDVKHDLEAIPGVLGVHELHVWRLDQKKAIASAHVRVSDPDIASFMEKAKIFSECLHAYGIHSATLQPELASPAERLEDTPDASEGVTPAMPSATSTARPSTEKCRVPCGSLCEELKCCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI55</accession>
    <name>W6ZI55_COCMI</name>
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        <submittedName>
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            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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            <begin position="1"/>
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            <begin position="17"/>
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        </location>
    </feature>
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            <begin position="19"/>
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    </feature>
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        <location>
            <begin position="60"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49653.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="5"/>
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        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0843">Virulence</keyword>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="chain" id="PRO_5004886876" evidence="4">
        <location>
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            <end position="725"/>
        </location>
    </feature>
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        <location>
            <begin position="242"/>
            <end position="287"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="674"/>
            <end position="721"/>
        </location>
    </feature>
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        <location>
            <begin position="643"/>
            <end position="662"/>
        </location>
    </feature>
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        <location>
            <begin position="643"/>
            <end position="659"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="725" mass="78215" checksum="FCBA3F0FFDEE82C8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIC5</accession>
    <name>W6ZIC5_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">Phytocyanin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_1583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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                <person name="Schackwitz W."/>
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    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683118.1">
        <property type="nucleotide sequence ID" value="XM_007684928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJU7"/>
    <dbReference type="STRING" id="930090.W6ZJU7"/>
    <dbReference type="GeneID" id="19117781"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1010"/>
    <dbReference type="eggNOG" id="KOG0728">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_2_0_1"/>
    <dbReference type="OrthoDB" id="1664597at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000006">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000068">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="165"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC50288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="389" mass="43310" checksum="05DB5A5899DDB77F" modified="2014-04-16" version="1">MALDTFFHNKIEAMKLEIIQGQAKLRRLEAQRNDYNSRVRLLREELGLLQQPGSYVGEVVKVMGTKKVLVKVHPEGKYVVDVADSVDITKLTAGKRVTLLSDSYKLEKLLPSSVDPLVSLMMVEKVPDSTYDMIGGLDQQIKEIKEVIELGLQHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAHHADCKFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRVEGSSGGDSEVQRTMLELLNQLDGFEPTKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPTVEARADILRIHSRSMNLTRGINLTKIAEKMNGCSGAELKGVCTEAGMYALRERRVHVTQEDFDLATAKVLNKHDDKATSLSKLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKB7</accession>
    <name>W6ZKB7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mpv17/PMP22 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_81972</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683106.1">
        <property type="nucleotide sequence ID" value="XM_007684916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKB7"/>
    <dbReference type="STRING" id="930090.W6ZKB7"/>
    <dbReference type="GeneID" id="19125969"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81972"/>
    <dbReference type="eggNOG" id="KOG1944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049109_3_1_1"/>
    <dbReference type="OrthoDB" id="10267969at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF80">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21070" checksum="63E156BEF1A0626F" modified="2014-04-16" version="1">MSMISQTLQGAALSVTSNVLAQAISSYKDDTPFALNYQSVLKFVVFSVLSTPPNIIWQGFLEDQFPTNVPSAPASTSSEKSASKHEPAKTSMSRRNVLIKFILDQTIGAVVNTLMFVSYMAYVNAQGKPGVNVSDVVTSDCINKTWPMMKDGYKFWPTISLISFLWIPVDKRIVFGASVGVVWGIYLSLAANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL09</accession>
    <name>W6ZL09_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964007">
        <property type="protein sequence ID" value="EUC44281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689184.1">
        <property type="nucleotide sequence ID" value="XM_007690994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL09"/>
    <dbReference type="GeneID" id="19123331"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37832"/>
    <dbReference type="HOGENOM" id="CLU_1366128_0_0_1"/>
    <dbReference type="OrthoDB" id="3693161at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="204" mass="22012" checksum="D762E547FD1E1795" modified="2014-04-16" version="1">MGNQGESTVLDSRSPKGNSSIRRLLHVLKHATKNRKTDTDSLKSKASDLPSMPSTPQSSSTDGNTEPTRFNANELRMRILRSNTSPAVPPTANPVTASGSTHQTLFSVPENAVSKNGAQEPSQAPIARSSTETPSASKPSRSRKSRQPTMITPELMQQIQISNKKRSGGALRDNGELRRKNLGTATVTNRAKAVVASPLRWSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL84</accession>
    <name>W6ZL84_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_21841</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682674.1">
        <property type="nucleotide sequence ID" value="XM_007684484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL84"/>
    <dbReference type="GeneID" id="19120129"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21841"/>
    <dbReference type="eggNOG" id="KOG2615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_54_5_1"/>
    <dbReference type="OrthoDB" id="10262656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF8">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="10"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="520"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="562"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="591"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="634" mass="68739" checksum="CF5D2BC36A278CAA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLD0</accession>
    <name>W6ZLD0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_87762</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685179.1">
        <property type="nucleotide sequence ID" value="XM_007686989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLD0"/>
    <dbReference type="STRING" id="930090.W6ZLD0"/>
    <dbReference type="GeneID" id="19127122"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87762"/>
    <dbReference type="eggNOG" id="KOG0069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_2_1"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12168">
        <property type="entry name" value="Mand_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000282">
        <property type="entry name" value="Glyoxylate reductase protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF257">
        <property type="entry name" value="GLYOXYLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="60"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="121"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="36522" checksum="43976C7D924F62E2" modified="2014-04-16" version="1">MSQRAALLIGKLSHAQKEWQQCAEVASKLYEYPDGNREDFISKCKSGEFDGVYALYRSNDSNPITGDFNAELLDALPKSLKYVCHNGAGYNNIDVAGCTKRGISVSSTPIAVNDATADVAIWLMLGALRNIKQSYMAVNSGKWRGNFSLGHDPKNKTLGILGMGGIGSAVAHRAKAFGMKIQYHNRRQLPASEENGAKYVSFEELLQTSDVLSLNLALNPSTTHIIGKDQFNQMKDGVVIVNTARGALIDEAALVDALKSGKVWTVGLDVFEEEPKIHPGLLECENAVLLPHVGTATFETQREMEILVLDNLKSAITSDKLLTQVPEQKTEKANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLX9</accession>
    <name>W6ZLX9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Splicing factor 3B subunit 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Pre-mRNA-splicing factor SF3b 155 kDa subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Spliceosome-associated protein 155</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_523</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3B1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007684309.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZLX9"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:siRNA-mediated pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Splicing factor 3B subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000088">
        <property type="entry name" value="Splicing factor 3b, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015016">
        <property type="entry name" value="SF3b_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038737">
        <property type="entry name" value="SF3b_su1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12097">
        <property type="entry name" value="SPLICING FACTOR 3B, SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SF3b1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Splicing factor 3B subunit 1" evidence="14">
        <location>
            <begin position="215"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="12">
        <location>
            <begin position="572"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="15">
        <location>
            <begin position="972"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="93"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="136"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
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            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00070532"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00076941"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00083579"/>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC50978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1187" mass="132636" checksum="CA807099A673AB45" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNV7</accession>
    <name>W6ZNV7_COCMI</name>
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        <recommendedName>
            <fullName evidence="9">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_96081</name>
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    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
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    </reference>
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        <cofactor evidence="1 5">
            <name>heme</name>
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        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Cyt_P450"/>
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        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
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        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF87">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALND-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EP450IV"/>
    </dbReference>
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        <property type="entry name" value="P450"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
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    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC45261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="60483" checksum="89713AB8FB37DF16" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPL8</accession>
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        <recommendedName>
            <fullName evidence="5">Pyruvate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_23005</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2-oxocarboxylate + H(+) = an aldehyde + CO2</text>
            <dbReference type="Rhea" id="RHEA:11628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="EC" id="4.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.1" evidence="4"/>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684068.1">
        <property type="nucleotide sequence ID" value="XM_007685878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPL8"/>
    <dbReference type="STRING" id="930090.W6ZPL8"/>
    <dbReference type="GeneID" id="19120361"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23005"/>
    <dbReference type="eggNOG" id="KOG1184">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_0_2_1"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004737">
        <property type="term" value="F:pyruvate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000949">
        <property type="term" value="P:aromatic amino acid family catabolic process to alcohol via Ehrlich pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02005">
        <property type="entry name" value="TPP_PDC_IPDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07038">
        <property type="entry name" value="TPP_PYR_PDC_IPDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000019">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000024">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012110">
        <property type="entry name" value="PDC/IPDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047214">
        <property type="entry name" value="TPP_PDC_IPDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047213">
        <property type="entry name" value="TPP_PYR_PDC_IPDC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452:SF30">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE ISOZYME 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036565">
        <property type="entry name" value="Pyruvt_ip_decrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="15">
        <location>
            <begin position="8"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="13">
        <location>
            <begin position="204"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="14">
        <location>
            <begin position="407"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR036565-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC49429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="598" mass="65545" checksum="C856ACA67E594D40" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQR7</accession>
    <name>W6ZQR7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_32853</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683651.1">
        <property type="nucleotide sequence ID" value="XM_007685461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQR7"/>
    <dbReference type="GeneID" id="19122191"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32853"/>
    <dbReference type="eggNOG" id="ENOG502QTQ2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013753_0_0_1"/>
    <dbReference type="OrthoDB" id="2115177at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF5">
        <property type="entry name" value="DUF907 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G06100)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887252" description="ML-like domain-containing protein" evidence="9">
        <location>
            <begin position="27"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="540"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="571"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="10">
        <location>
            <begin position="28"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="629"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="691"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="723"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="732" mass="80745" checksum="D459DB8F2BE70477" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQT2</accession>
    <name>W6ZQT2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_93827</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963972">
        <property type="protein sequence ID" value="EUC46056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687420.1">
        <property type="nucleotide sequence ID" value="XM_007689230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQT2"/>
    <dbReference type="GeneID" id="19128336"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93827"/>
    <dbReference type="HOGENOM" id="CLU_1309908_0_0_1"/>
    <dbReference type="OrthoDB" id="3659462at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="210" mass="24530" checksum="0021FF7371B61FD2" modified="2014-04-16" version="1">MTQNSKRVLTASTYQQLAPPACYDTRPYPPNMSHEMQISQLRHAPQQLMTGRPTDIRMGAQITMRDDKTISKTWHDEWETEPRPFGPRRPLALLNQPVQINLRTHPRNAKRVYLNHWDRQHEPNGTFAQRLVIEKQQVRMDRRTQIIRAEHQDERRRKVKQAAMNADVIDLTGDGTTDEKSSWRHDSVGHVGFSGSSGEMIHAWDYSWQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZR15</accession>
    <name>W6ZR15_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1264 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OBAP family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683571.1">
        <property type="nucleotide sequence ID" value="XM_007685381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZR15"/>
    <dbReference type="STRING" id="930090.W6ZR15"/>
    <dbReference type="GeneID" id="19126245"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83399"/>
    <dbReference type="eggNOG" id="ENOG502QR3B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071931_2_1_1"/>
    <dbReference type="OrthoDB" id="1901244at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010686">
        <property type="entry name" value="OBAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360:SF0">
        <property type="entry name" value="OIL BODY-ASSOCIATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06884">
        <property type="entry name" value="DUF1264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25935" checksum="0759280F7F7CE674" modified="2014-04-16" version="1">MDSLPVNNKTAGEAESTYNKALETGAGATQNFAPVKRVCAHLNAFHAYADDPKRAAVEANHYCAHLNDEVRQCILYDSPEPGARIIGIEYMISPRLYETLPASEQELWHSHVFEVKSGMLIMPRPASMPEAAWEIAENREMEEVIQLYGKVYHLWQTDRGDKLPLGPPQLMTSYTAEDQMPDFEERMRERDQRFGSDYRRKAGVREYIEVPRVHEKADATWAKGGLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRL2</accession>
    <name>W6ZRL2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">vesicle-fusing ATPase</fullName>
            <ecNumber evidence="3">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_35966</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="3"/>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687099.1">
        <property type="nucleotide sequence ID" value="XM_007688909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRL2"/>
    <dbReference type="STRING" id="930090.W6ZRL2"/>
    <dbReference type="GeneID" id="19122907"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35966"/>
    <dbReference type="eggNOG" id="KOG0739">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_21_2_1"/>
    <dbReference type="OrthoDB" id="29072at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990621">
        <property type="term" value="C:ESCRT IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070676">
        <property type="term" value="P:intralumenal vesicle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090148">
        <property type="term" value="P:membrane fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036258">
        <property type="term" value="P:multivesicular body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02678">
        <property type="entry name" value="MIT_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19521">
        <property type="entry name" value="RecA-like_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.80:FF:000004">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000043">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000015">
        <property type="entry name" value="vacuolar protein sorting-associated protein 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045253">
        <property type="entry name" value="VPS4_MIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF83">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MIT" evidence="15">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="167"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="74"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC46346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="437" mass="48120" checksum="024A4E477B14FB0B" modified="2014-04-16" version="1">MSNADFLGRAIETVKKAIETDTAGEYEKAYQLYYSALELFMLALKWEKNQKSKEMIRGKVAEYMERAEKLKQHLNQNDASNRKKPAAMGSNGKAAGGSGKGGGDDDEGEQDADSKKLRGALAGAILSEKPNIRWEDVAGLEAAKEALKEAVILPIKFPHLFTGKRQPWKGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWMGESERLVKQLFGMARENKPSIIFIDEIDALCGPRGEGESEASRRIKTELLVQMDGVGKDSKGVLILGATNIPWQLDSAIRRRFQRRVHISLPDLPARMKMFELAVGNTPCELNQADYRKLAELSEGYSGSDISIAVQDALMQPVRLIQTATHYKPVEVDGQTKWTPCSPGDPQAHEKSWTDLDGDQLLEPPLKVKDFIKAIKASRPTVSGEDLQRSVEWTKEFGSEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU71</accession>
    <name>W6ZU71_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_80041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682428.1">
        <property type="nucleotide sequence ID" value="XM_007684238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZU71"/>
    <dbReference type="GeneID" id="19125590"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80041"/>
    <dbReference type="eggNOG" id="ENOG502S0Z5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035325_0_0_1"/>
    <dbReference type="OrthoDB" id="4092340at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="563" mass="59892" checksum="812B02A69044279B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUN5</accession>
    <name>W6ZUN5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="9">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_21243</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 9">Belongs to the E3 ubiquitin-protein ligase UBR1-like family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="9"/>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682085.1">
        <property type="nucleotide sequence ID" value="XM_007683895.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZUN5"/>
    <dbReference type="GeneID" id="19120024"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21243"/>
    <dbReference type="eggNOG" id="KOG1140">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000684_1_0_1"/>
    <dbReference type="OrthoDB" id="26387at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16482">
        <property type="entry name" value="RING-H2_UBR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19673">
        <property type="entry name" value="UBR-box_UBR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.30:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase UBR2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044046">
        <property type="entry name" value="E3_ligase_UBR-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039164">
        <property type="entry name" value="UBR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055194">
        <property type="entry name" value="UBR1-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497:SF24">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497">
        <property type="entry name" value="UBIQUITIN LIGASE E3 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18995">
        <property type="entry name" value="PRT6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22960">
        <property type="entry name" value="WHD_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02207">
        <property type="entry name" value="zf-UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBR-type" evidence="11">
        <location>
            <begin position="85"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="UBR-type" evidence="8">
        <location>
            <begin position="85"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="398"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="473"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1283"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="411"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="486"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1292"/>
            <end position="1302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC51254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="2151" mass="243217" checksum="61DD43DB85244313" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVG3</accession>
    <name>W6ZVG3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_89471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685801.1">
        <property type="nucleotide sequence ID" value="XM_007687611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZVG3"/>
    <dbReference type="GeneID" id="19127486"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89471"/>
    <dbReference type="eggNOG" id="ENOG502SDAI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_657185_0_0_1"/>
    <dbReference type="OrthoDB" id="3692311at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="421" mass="45270" checksum="CDC7ACFB699294BC" modified="2014-04-16" version="1">MSAYLAARQAFSPSCPSGGTWWACGYGTYFVGCCARDPCDITCAQGNLYPGAFDPKAYGTFPDATCGTGSKFYTCSAGQTFWGCCKTNPCAQSGCPDGDLEPAILNRDDLRSAYHATGSATTSSTSGPTAAAQKSDDGVPVGAIAGGAAGGAFALAAIIGIIVWWLCLRRKKKAKAKAAEHYGETNGDGLPVNGMSEFHNKHHRNQSSDSPPSYTSPNPNHPNGFYNPPTTHTYQHTYDPTHTYTAPQELPLSTPITPQTPAQFRTHKSMYSHARGPSELSGDEPRNELDSGDPASPELSGSTGAVVSPATRKWSWDDRKEKVELATQHEHEHDGEAHIGVAIGEPRAEGARVMPVWREQRVGEVEVESPREMEGEAALEEGHRGRGSRGRAPQGLGFIEILEDMAERRGEMDAQRAERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWP4</accession>
    <name>W6ZWP4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acyl-protein thioesterase 1</fullName>
            <ecNumber evidence="3">3.1.2.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Palmitoyl-protein hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_87834</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19233"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:7896"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="3.1.2.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.22" evidence="3"/>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685247.1">
        <property type="nucleotide sequence ID" value="XM_007687057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWP4"/>
    <dbReference type="STRING" id="930090.W6ZWP4"/>
    <dbReference type="GeneID" id="19127138"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87834"/>
    <dbReference type="eggNOG" id="KOG2112">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049413_3_8_1"/>
    <dbReference type="OrthoDB" id="2418081at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000010">
        <property type="entry name" value="Acyl-protein thioesterase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF17">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="13">
        <location>
            <begin position="6"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC48221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="237" mass="26219" checksum="8C75FBA366AC7D02" modified="2014-04-16" version="1">MAHKAPLIVPALKRHTATVIVAHGLGDSGAGWIFLAENWRRRSKFEEVSFIFPNAPNIPISLNMGMSMPGWYDIKELGNLDGRSEDEQGIIQSQKYFHSLIDQEVSKGIPANRIVIGGFSQGGAMSILSGVTYKEQLGGIFGLSCYLLLQNKIKDMIPTSNPNQNTPIFMGHGDADQVVAHKWGKKSAEELEKHGYKVDFRTYKGLVHSADPDEIDHLESYLNQQIPPLDKKSESSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYU2</accession>
    <name>W6ZYU2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_86112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684672.1">
        <property type="nucleotide sequence ID" value="XM_007686482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYU2"/>
    <dbReference type="GeneID" id="19126799"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86112"/>
    <dbReference type="HOGENOM" id="CLU_3074127_0_0_1"/>
    <dbReference type="OrthoDB" id="10303799at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="53" mass="5955" checksum="EBA14368CD427DDE" modified="2014-04-16" version="1" fragment="single">TLSETEAHSFRHLLPCRSDFIDRHRTQPVRSTATSELPQSANLAAIRARLPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZ91</accession>
    <name>W6ZZ91_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_23247</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684398.1">
        <property type="nucleotide sequence ID" value="XM_007686208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZ91"/>
    <dbReference type="GeneID" id="19120397"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23247"/>
    <dbReference type="eggNOG" id="ENOG502R8I5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_4_2_1"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887369" description="FAD-binding PCMH-type domain-containing protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="111"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC49071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="560" mass="60443" checksum="6243AA334CFB0653" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZH0</accession>
    <name>W6ZZH0_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_2014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZH0"/>
    <dbReference type="GeneID" id="19119987"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2014"/>
    <dbReference type="eggNOG" id="ENOG502T154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076163_1_1_1"/>
    <dbReference type="OrthoDB" id="5289641at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39697:SF2">
        <property type="entry name" value="CYANOVIRIN-N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39697">
        <property type="entry name" value="RICIN B LECTIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="Actin-crosslinking proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="197" mass="22317" checksum="3943F8A7274D9B69" modified="2014-04-16" version="1">MAQAYPIIFDNVDSETSTVCTSPTVCTTSPVHTPSTTVSTPTTSKDHQKWENFQSSIPWPGRTFIIRSHDTGHVITFLDGEIILDKPGGFGTFRWRCVEKRGWLGFRDPVSARYMGYDSRGWIRCAVDKQNDWEYICVRKRPEGGYVLLVLVENKLLPMGVCAQETAGVVRQRVKIRDWNSEGIVWDFIEVPCPSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZP4</accession>
    <name>W6ZZP4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_2048</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684280.1">
        <property type="nucleotide sequence ID" value="XM_007686090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZP4"/>
    <dbReference type="GeneID" id="19119995"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2048"/>
    <dbReference type="eggNOG" id="ENOG502S025">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_4_1"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="31"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="380" mass="42157" checksum="FE4FEAD2CFBE3A50" modified="2014-04-16" version="1">MAGSLSENSRGREAVVISSVFTGLALIIVILRLYTRLYILRCAGVEDLGIALAMLCSIGLTICIGIQAEFGMGKHFRDVSQHDMGIFLRAFWCSLMVYYLSLGLTKGSMLLQYRRIFPTKVFQIANWITMAVVICYTIWTVFSSIFACIPVRAFWTKEKASCINQFAMWFTNAAINILTDFAIILLPIPVIRGLNLGKRQKIGLISIFAVGGFVCIVSILRLQSLVAISNSSDQTYDNPPAATWSSVETNVGIICACLPLLRPLLAKYFPRVFPSRHRSQYSRPNYPAAYGSKGGSKILRSKNEYVLEGTKRSRESNDETRDIQVVTDIHVRVEGSEGVQANGWKTQTPNPHWDDSLSAKDAETASTTEMLVDAAPLSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0E3</accession>
    <name>W7A0E3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_84352</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF79">
        <property type="entry name" value="HSP70 FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15200)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC49496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="636" mass="70546" checksum="D5D75481FE59852E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3X0</accession>
    <name>W7A3X0_COCMI</name>
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        <recommendedName>
            <fullName evidence="8">mRNA decay factor PAT1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_569</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PAT1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC50716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684445.1"/>
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    <dbReference type="STRING" id="930090.W7A3X0"/>
    <dbReference type="GeneID" id="19124703"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_569"/>
    <dbReference type="eggNOG" id="KOG4592">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012622_1_0_1"/>
    <dbReference type="OrthoDB" id="74835at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039900">
        <property type="entry name" value="Pat1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019167">
        <property type="entry name" value="PAT1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551:SF0">
        <property type="entry name" value="PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551">
        <property type="entry name" value="TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09770">
        <property type="entry name" value="PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="mRNA decay factor PAT1" evidence="8">
        <location>
            <begin position="1"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="106"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="210"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="257"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="854" mass="95492" checksum="AD1D77ECB2A1004F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A5H0</accession>
    <name>W7A5H0_COCMI</name>
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        <recommendedName>
            <fullName evidence="3 6">DNA replication complex GINS protein SLD5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_31515</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS4/SLD5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682151.1">
        <property type="nucleotide sequence ID" value="XM_007683961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A5H0"/>
    <dbReference type="STRING" id="930090.W7A5H0"/>
    <dbReference type="GeneID" id="19121884"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31515"/>
    <dbReference type="eggNOG" id="KOG3176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071893_1_1_1"/>
    <dbReference type="OrthoDB" id="338231at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071162">
        <property type="term" value="C:CMG complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd11711">
        <property type="entry name" value="GINS_A_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21692">
        <property type="entry name" value="GINS_B_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.5.60:FF:000003">
        <property type="entry name" value="DNA replication complex GINS protein SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008591">
        <property type="entry name" value="GINS_Sld5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031633">
        <property type="entry name" value="SLD5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038749">
        <property type="entry name" value="Sld5_GINS_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206">
        <property type="entry name" value="SLD5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16922">
        <property type="entry name" value="SLD5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007764">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="57"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein SLD5 C-terminal" evidence="8">
        <location>
            <begin position="169"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR007764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC51381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="225" mass="25613" checksum="F116EA6E0B7BCD93" modified="2014-04-16" version="1">MDIDDLLAEVAVDSTPQESRDLQELTRCWVAERVAPEILPWPTDLMARVLERIARQIELVEDQTGNMDPKTNFTLIIIQTELERFKFLVRSFLRARIKKIDTHPLHISAQHTSSLDTPTPLLSPAEHQYLTSHQALLAAHYASSFLSQFPASLQRLDDTTGGISMVDKPDEDKAVFVRALRDVGEIFVEGTDRRFEMKRGDVWVVRWSAVRRWCVGCGTGDVELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YL49</accession>
    <name>W6YL49_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytocyanin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_78906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964221">
        <property type="protein sequence ID" value="EUC39922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693549.1">
        <property type="nucleotide sequence ID" value="XM_007695359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YL49"/>
    <dbReference type="STRING" id="930090.W6YL49"/>
    <dbReference type="GeneID" id="19125425"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_78906"/>
    <dbReference type="eggNOG" id="ENOG502S40X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115015_0_0_1"/>
    <dbReference type="OrthoDB" id="2331100at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF16">
        <property type="entry name" value="RICH PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="16762" checksum="054122186D59F0FE" modified="2014-04-16" version="1" fragment="single">MHWSTGTTTHPKISQPTSTIIVGDKGKLVFSPSSLNASIGTTIAFNFLALNHTLTQSQLQDPCRNASGFDSGFNQFNPTNISGRFVVEYTVTSDEPQWFFCAQTARLAHCQAGMVFSLNPRGLHAQFVSNAMEKIPSTTSSHEHACSLPISSTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLP0</accession>
    <name>W6YLP0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_109587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964195">
        <property type="protein sequence ID" value="EUC40127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693355.1">
        <property type="nucleotide sequence ID" value="XM_007695165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLP0"/>
    <dbReference type="GeneID" id="19119461"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109587"/>
    <dbReference type="HOGENOM" id="CLU_1570351_0_0_1"/>
    <dbReference type="OrthoDB" id="3681621at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="170" mass="18311" checksum="27628EA955F85F20" modified="2014-04-16" version="1">MAQLYAISGSLFPASATKADKEGFEDLAKALIIATRQPIYNATEDIDGTLELLDAHSAPEWQTGLFVGMGLVSPICATLDTSTRKLRRAGKLMHPLANSYNGKLIMRRKHVGARGANPGAGSYEQGSNDVSAHNEVFAHLDIGTSNESAATPEVADELDRVMRPVSFLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YM88</accession>
    <name>W6YM88_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein FYV10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_109019</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FYV10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964172">
        <property type="protein sequence ID" value="EUC40357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693126.1">
        <property type="nucleotide sequence ID" value="XM_007694936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YM88"/>
    <dbReference type="STRING" id="930090.W6YM88"/>
    <dbReference type="GeneID" id="19119351"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109019"/>
    <dbReference type="eggNOG" id="KOG0396">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027445_2_0_1"/>
    <dbReference type="OrthoDB" id="1933455at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CTLH" evidence="10">
        <location>
            <begin position="182"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="RING-Gid-type" evidence="11">
        <location>
            <begin position="356"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="8">
        <location>
            <begin position="356"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="71"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC40357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="48091" checksum="3C41596D7A1D4233" modified="2014-04-16" version="1">MAELTSTKLNAESHLLLDQPLLRMPYELSRRNFKNAQRVIEHSSSALPTALSATAKAANKNASPEATLSSLDSLITKMQGLKRKLEGLHEEENRLHRAAKARLQHLQDLYSVQSLVDVKYDEWSRTRLSRLLVDYLLREGYAESATCLAQSKGIEDLVDVEAFVACHKIERSLREGMSTALALEWCKEHGKELKKGGSMLEFELRLQQYIELVRQGHEAGLSAMDGLEGEEGGMHGVSIGSRGEGGGEAKLVEARAHAKKYLSASGDFTLMRQAAGMLAYRPWDEVEPYASLYSPSRWSYLADLFVSTHHTLYSLPPRPLLHIALSAGLSALKTPACHSEYIPSATNAASSATTVCPICSAELKELARNVPYALHTKSIVEDAPVVLPNGRIYGSERLRIFNEKVGTEPGYVRDPVAGLTGDKWKESEVRKVYIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNI5</accession>
    <name>W6YNI5_COCMI</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="136" mass="15063" checksum="4EE13EAA9029129B" modified="2014-04-16" version="1">MHTTAEYRWAVGKAWTLHHARPRLHGGQAPACWPQCNTQGATTFGTAVFNMVGCSTVTGGGWAKCCSCNGYVLSDALLACFCFVFFSTHTSLIVNHSPCRGADPLMARRKHDLISLFSFHFWVRFAGLCFLFSFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPF8</accession>
    <name>W6YPF8_COCMI</name>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964337">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPF8"/>
    <dbReference type="GeneID" id="19119738"/>
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    <dbReference type="HOGENOM" id="CLU_2654126_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="76" mass="8927" checksum="302A629080A6296C" modified="2014-04-16" version="1">MVSDHLRRCINSLIRVEPLGWAHKWCICANTLIEYLAMLTNIMVARSHTMFWCGLALTLWMWKDAKIDQIIPRGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQA6</accession>
    <name>W6YQA6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">YTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_110514</name>
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    <organism evidence="5 6">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964247">
        <property type="protein sequence ID" value="EUC39810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQA6"/>
    <dbReference type="STRING" id="930090.W6YQA6"/>
    <dbReference type="GeneID" id="19119611"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110514"/>
    <dbReference type="eggNOG" id="KOG1902">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011694_2_0_1"/>
    <dbReference type="OrthoDB" id="306690at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990247">
        <property type="term" value="F:N6-methyladenosine-containing RNA reader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057720">
        <property type="entry name" value="RRM_YTH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF3">
        <property type="entry name" value="YTH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25701">
        <property type="entry name" value="RRM_YTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="289"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="YTH" evidence="4">
        <location>
            <begin position="423"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="365"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="543"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC39810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="660" mass="71238" checksum="5EE596D645662271" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQY0</accession>
    <name>W6YQY0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">CSC1/OSCA1-like 7TM region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_109764</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964204">
        <property type="protein sequence ID" value="EUC40045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693424.1">
        <property type="nucleotide sequence ID" value="XM_007695234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQY0"/>
    <dbReference type="GeneID" id="19119498"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109764"/>
    <dbReference type="eggNOG" id="KOG1134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002458_2_2_1"/>
    <dbReference type="OrthoDB" id="1076608at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF20">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="537"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="568"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="9">
        <location>
            <begin position="17"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="10">
        <location>
            <begin position="116"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="8">
        <location>
            <begin position="305"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="671" mass="75720" checksum="336155355AC2D769" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRA2</accession>
    <name>W6YRA2_COCMI</name>
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        <recommendedName>
            <fullName evidence="9">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_109792</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964205">
        <property type="protein sequence ID" value="EUC40038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693440.1">
        <property type="nucleotide sequence ID" value="XM_007695250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRA2"/>
    <dbReference type="STRING" id="930090.W6YRA2"/>
    <dbReference type="GeneID" id="19119507"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109792"/>
    <dbReference type="eggNOG" id="KOG1287">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_3_6_1"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000042">
        <property type="entry name" value="Similar to amino acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF402">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="55664" checksum="7177988C1FF512E5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRY4</accession>
    <name>W6YRY4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">catechol O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_104097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.6" evidence="1"/>
    <dbReference type="EMBL" id="KI964069">
        <property type="protein sequence ID" value="EUC42207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691275.1">
        <property type="nucleotide sequence ID" value="XM_007693085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRY4"/>
    <dbReference type="STRING" id="930090.W6YRY4"/>
    <dbReference type="GeneID" id="19118440"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104097"/>
    <dbReference type="eggNOG" id="KOG1663">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050461_0_0_1"/>
    <dbReference type="OrthoDB" id="186626at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006584">
        <property type="term" value="P:catecholamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836:SF2">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0128">Catecholamine metabolism</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="282" mass="31024" checksum="630B2D9D1D82C8C2" modified="2014-04-16" version="1">MGSFDQSKAYAAQEEEGAFFDDGREIELLHFVYSHPNIDKIRDSPEGVLAAIDEYGRTKKYLMNVGEDKGRIVTDLIAEVKPKTMIELGGYVGYSCILFADAVRKAGGERYFSFERDPAFAAVIMSLADLAGLSDLVKVVVGSSDEGIARLVASGQLKHVDLMFLDHYKPAYTTDLKLCEELGLITKGSVLAADNVIKPGNPPYLKYVRSSVEEKVKEAGENGQTNLNGIAETNVKMYEKRYGKAKFSESKGNPHLQYESRLINSYEPTGVPDGIEITRCVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSI4</accession>
    <name>W6YSI4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_9664</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="KI964163">
        <property type="protein sequence ID" value="EUC40463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693012.1">
        <property type="nucleotide sequence ID" value="XM_007694822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSI4"/>
    <dbReference type="STRING" id="930090.W6YSI4"/>
    <dbReference type="GeneID" id="19128888"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9664"/>
    <dbReference type="eggNOG" id="KOG1871">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008279_3_0_1"/>
    <dbReference type="OrthoDB" id="429671at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF687">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="432"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="103"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="195"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="823"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="348"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="887" mass="97615" checksum="73D2EFE3355A3B8F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSL1</accession>
    <name>W6YSL1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_41181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964160">
        <property type="protein sequence ID" value="EUC40498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692982.1">
        <property type="nucleotide sequence ID" value="XM_007694792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSL1"/>
    <dbReference type="GeneID" id="19124013"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41181"/>
    <dbReference type="HOGENOM" id="CLU_1089924_0_0_1"/>
    <dbReference type="OrthoDB" id="3688227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="257" mass="29042" checksum="1597DCBAAD337039" modified="2014-04-16" version="1">MNALDFLVEFVHLEGTSDHLLPQHNQNTSASKHPICKTGVEMMTSAHAIAYEQYHFAQQASEQEAAFTIPTNPLSTQHMFPVSASHLPDTSVANFEHHDIPHPSIEHDDHASQTFTGHPLKEERDESSHKAISFISQSYCQQSNGHAPWNTGYEASNTQPPVLNTRYDPHTPYMSQPFQQHETHYISSSENASPVQIHCTNSICRCWTQEPQTYHPVENTWPPWNTTTHTPHGLEVPPTYTEWAPGKSTRRPNFSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSP0</accession>
    <name>W6YSP0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">50S ribosomal protein YmL27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_108287</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL41 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964149">
        <property type="protein sequence ID" value="EUC40645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692846.1">
        <property type="nucleotide sequence ID" value="XM_007694656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSP0"/>
    <dbReference type="STRING" id="930090.W6YSP0"/>
    <dbReference type="GeneID" id="19119215"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108287"/>
    <dbReference type="eggNOG" id="KOG4756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131055_2_0_1"/>
    <dbReference type="OrthoDB" id="408933at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019189">
        <property type="entry name" value="Ribosomal_mL41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09809">
        <property type="entry name" value="MRP-L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC40645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="15221" checksum="F9516EA3644F821C" modified="2014-04-16" version="1">MFKPTPSLQKMLRRLPLSPKQAGKEYYKGNRVGSMGTINKYGNFTPDWSKIRTYVYPIHGTKNSELTPFVDASLEKVRDLDSGTAQNYPKHFTGEDYLRAWKMSGGHDIVETADGASDSSRNMPTPFEERPATKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSX5</accession>
    <name>W6YSX5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_108266</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964149">
        <property type="protein sequence ID" value="EUC40638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692839.1">
        <property type="nucleotide sequence ID" value="XM_007694649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSX5"/>
    <dbReference type="GeneID" id="19119213"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108266"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_7_0_1"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF5">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="490" mass="55618" checksum="1BA6B5EFBA4CF7C0" modified="2014-04-16" version="1">MEKPSSTVPFREVVIIGCGFGGLVMACQLKRKLQFNDFIMYERNAGLGGTWHHNRYPGASADVFGAAYQISFAPEPRFTRTFPIWNELHDYMEKVADRYNVIPHMKFGISWEGSVWMPETRCWRVVLRDCATGETLTQMCKVLISATGHLVDPKQLDVQGKDIFKGKIVHSSLWTSDIDVKGKSVVVLGNGSTAVQLIPSILEDVKECTQIQRAPQWILHRPNPALPAAMLTLLAYVPFLFTVLRTTLFAITEAFFHVVGNRIPQISKNHLRKFQVPEEYYDLLTPSYRPGCKRLVFASDYLGCLKNPKLLLVQDEIAFLREKSVVTRSGKEYACDMLLLAHGFESETFKLPLIGRDGNTPEKHWAVAGGPSCYKGIAMHNFPNFFTIRGPNMASGHNSVIWYIEATVELILNVITPLIQGKVTQVEVTAEAESKYVNKVQEACRKGVWGSACNTYYVTKKGWNHTMYPWNSYSLWWFRFVNKKDWTVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT54</accession>
    <name>W6YT54_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_9395</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964140">
        <property type="protein sequence ID" value="EUC40775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692702.1">
        <property type="nucleotide sequence ID" value="XM_007694512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT54"/>
    <dbReference type="GeneID" id="19128358"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9395"/>
    <dbReference type="eggNOG" id="ENOG502QS4K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036005_1_0_1"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF10">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="8">
        <location>
            <begin position="39"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="354" mass="39834" checksum="4C90785F38BBB69F" modified="2014-04-16" version="1">MGWLLEGEAPKATPLGGGPYSRLKEPMKLSNALDGVEYNDITSLLGREYPKASLTEWMNAPNSDELIRDLAITVSQRGVVVFRAQDGVDNEMLKKIALRLGELTGRPEECGLHIHPVFNSAREGLEEDNQINCVSSDDRKKLYNSKKAQSHNNWHSDVGFEAVPGDYSVFIVPEIPETGGDTMFASGCELYDRLSKPMQQFVESLTIINGSPSLEDAVQANNPNLYAKDRGCPQNSGLHFRHEQPFVRTNPVTGWKSIYALGQNTISIKDLAQEESQMLLDWVISILYKNHDTTVRIKYLNRNDLVIWDNRSTFHCVTWDYDHLGPRKGKRALGIGEKPYFDPNSKSRTEDLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTX6</accession>
    <name>W6YTX6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_72243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Han J."/>
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                <person name="Salamov A."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Schackwitz W."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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    <feature type="compositionally biased region" description="Gly residues" evidence="1">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Grimwood J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <end position="666"/>
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    </feature>
    <feature type="domain" description="MIF4G" evidence="5">
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            <end position="889"/>
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        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="922"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="955"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1007"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1064"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1175"/>
            <end position="1193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC43382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1204" mass="136428" checksum="909717E694E42CA0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW63</accession>
    <name>W6YW63_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Intradiol ring-cleavage dioxygenases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_105247</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964086">
        <property type="protein sequence ID" value="EUC41783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691690.1">
        <property type="nucleotide sequence ID" value="XM_007693500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW63"/>
    <dbReference type="GeneID" id="19118653"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105247"/>
    <dbReference type="eggNOG" id="ENOG502QWDJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046727_2_0_1"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03461">
        <property type="entry name" value="1_2-HQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039390">
        <property type="entry name" value="1_2-HQD/HQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF7">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="8">
        <location>
            <begin position="29"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="7">
        <location>
            <begin position="108"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC41783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="36219" checksum="B50D3C7181C354BB" modified="2014-04-16" version="1">MSAPINLKDLTTENITENVHAINSQCASPRLKYILERAVTHLHELAREVRLTTDEWMTAILFLTSVGQISSETRQEFILLSDILGLSLLVDSIDHPKPKGSTEGTVLGPFHTHEAENRGQGSLISHDPDGEPLLVLCTLKDVNGNPISGAQIDVWETDSKGFYDVQHADRTGPDGRAVLTSDEDGNFWFKAIVPVPYPIPHDGPVGKLLKLLNRHPYRPSHIHFMFKKDGYDPLITALYLKNDPYESTDAVFGVKDSLVVPLQRVVNKSQAKTYEVELGSALISYDFVLVTDEAAVELRRQKAKEAMAVLSGKFRFIDNLPVPDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWV6</accession>
    <name>W6YWV6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_104537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964075">
        <property type="protein sequence ID" value="EUC42035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691436.1">
        <property type="nucleotide sequence ID" value="XM_007693246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWV6"/>
    <dbReference type="GeneID" id="19118530"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104537"/>
    <dbReference type="HOGENOM" id="CLU_3013857_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="56" mass="5860" checksum="53CC8B44841B924A" modified="2014-04-16" version="1">MVSTRCGSAGVIGIFVAPRIFTPTDRLHTTKSPMASNITARLALSDSELIGPAACR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX47</accession>
    <name>W6YX47_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_8274</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691369.1">
        <property type="nucleotide sequence ID" value="XM_007693179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX47"/>
    <dbReference type="STRING" id="930090.W6YX47"/>
    <dbReference type="GeneID" id="19126114"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8274"/>
    <dbReference type="eggNOG" id="KOG1687">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055737_1_3_1"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12280:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit B 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005012">
        <property type="entry name" value="PRK06411.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56770">
        <property type="entry name" value="HydA/Nqo6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase-like 20kDa subunit" evidence="5">
        <location>
            <begin position="95"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="220" mass="24664" checksum="7B6A02537C11545C" modified="2014-04-16" version="1">MATTRMLSIAAPRLCLVPRTPPVLSLPLATQVNARRHQSQSPKHAGSKSLLPRNTPLSSQAEPNNAVEYVLTTFDQIANWARQGSVWPLTFALACCGIEMMHCSMPRYDQDRLGIIFRASPRQADIMIVAGTVTNKMASAVRLCYDQMPDPKWVISMGSCANGGGYYHYSYSVLRGVDRILPVDIYIPGCPPTAEALLYGIFQLQKKMRQQRVTRMWYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX56</accession>
    <name>W6YX56_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">ATP synthase protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_8246</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14 15">Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 15">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Mitochondrion inner membrane</location>
            <topology evidence="15">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the ATPase protein 8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964072">
        <property type="protein sequence ID" value="EUC42125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691341.1">
        <property type="nucleotide sequence ID" value="XM_007693151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX56"/>
    <dbReference type="STRING" id="930090.W6YX56"/>
    <dbReference type="GeneID" id="19126054"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8246"/>
    <dbReference type="eggNOG" id="ENOG502SC5X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148163_0_0_1"/>
    <dbReference type="OrthoDB" id="3916939at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009230">
        <property type="entry name" value="ATP_synth_su8_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36101">
        <property type="entry name" value="ATP SYNTHASE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36101:SF1">
        <property type="entry name" value="ATP SYNTHASE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05933">
        <property type="entry name" value="Fun_ATP-synt_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 15" id="KW-0138">CF(0)</keyword>
    <keyword evidence="8 15" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10 15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU368038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC42125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="99" mass="11187" checksum="07B31CE9AD829809" modified="2014-04-16" version="1">MNARFLRPFARAAFRAPTAVRPAAMARPALVASQTKKTEVSPQQMTVLKSAMPQLIPFFFVNETTVAFILLPSLIYVFSKYILPQRVRLFAARLFISKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXB1</accession>
    <name>W6YXB1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_109498</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964191">
        <property type="protein sequence ID" value="EUC40159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693315.1">
        <property type="nucleotide sequence ID" value="XM_007695125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXB1"/>
    <dbReference type="GeneID" id="19119446"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109498"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000018">
        <property type="entry name" value="MFS transporter permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="47"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="487" mass="53724" checksum="D5A55A9223836F5D" modified="2014-04-16" version="1">MSNEREEKVDAVLKESLNPPATGSNSGDYIFDEIEERKLVRKVDWRLLPILGALYSIALIDRTNISNARVAGMGRDLRLDVGDRYTIVLVMFFPTYFLLELPSNIVLRRVGSANWLSFIAVSWGAVMIGQAFVKSWISLTICRVLLGSFEAGFFPGCVYLITCWYRRYETQKRLGLFYLFSVGIGGLASILAYGLMQMEGLSGVRGWQWIFIIEGILTVVVAVAAWFIILDFPDKAEKKGFLTSAEAAVIMQRIEDDRGDSVDDALTWAKFGLHVRDVKLWGYATLFMSTTMPAYAFSYFLPVILLGMGYSAGQANALAAPPSLVAMIGAFGFAWLGDKYRVRAPIIAAQSIITIVGLMIVAYAENNGARYFGTFLGVCGCQGNVPAILAYQSNNIRGQSKRSVGSALQIGFGAIGGIIASTVFTQKEAPRYLTGLWVTAALQFYILGVLICFTVYFRKQNKVVEKQMANGEPLAEREGQAGFKYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXF6</accession>
    <name>W6YXF6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_6510</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689343.1">
        <property type="nucleotide sequence ID" value="XM_007691153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXF6"/>
    <dbReference type="STRING" id="930090.W6YXF6"/>
    <dbReference type="GeneID" id="19124980"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6510"/>
    <dbReference type="eggNOG" id="KOG3155">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094365_1_0_1"/>
    <dbReference type="OrthoDB" id="200404at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051654">
        <property type="term" value="P:establishment of mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1760.10:FF:000002">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1760.10">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007204">
        <property type="entry name" value="ARPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036753">
        <property type="entry name" value="ARPC3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12391">
        <property type="entry name" value="ARP2/3 COMPLEX 21 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04062">
        <property type="entry name" value="P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016315">
        <property type="entry name" value="ARP2/3_P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69060">
        <property type="entry name" value="Arp2/3 complex 21 kDa subunit ARPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="190" mass="21525" checksum="9EE9659D5E175B3D" modified="2014-04-16" version="1">MPAYHSVFLDEPNQQLIGNFALLPLRTRTRGPAVQLPALPADVTELTIEASHDSYDPLDEVLALFRANTFFRNFEIKGPADRVLIYGILYVSEVLGKIKPNMSRREAEKAVMNSALDTNFAIPGDAGFPLNQAFEAPSDRNSAEVLRQYIMQMRQELATRLLNRVYADDTNTPSKWWLSYTKRKFMGKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXI5</accession>
    <name>W6YXI5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_109313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964182">
        <property type="protein sequence ID" value="EUC40249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693236.1">
        <property type="nucleotide sequence ID" value="XM_007695046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXI5"/>
    <dbReference type="GeneID" id="19119407"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109313"/>
    <dbReference type="HOGENOM" id="CLU_1170479_0_0_1"/>
    <dbReference type="OrthoDB" id="3684928at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="237" mass="25265" checksum="219218DB4DF9EEFD" modified="2014-04-16" version="1">MLAGLQKYAQAATVGDLAVEFNAAALSVKDGIVAEATPDNGVAVRIGTEEKMPGTYTLVISKNGTKCDSPSSMCIMQPGLISSSLKTMVDGKMVFELVDPSKPAAQAPSVAKLSVEKLPLMQGSTQVLLNTTDGQPKDVADLLTGPWSKTHTVARKVLSATKTLSTSGGLLDWLNIPSKTVEARSRKTRRPKRPARNITFDFLNNDNKDGEEKNYGVMLHTSSFGWAAAFLAVLVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY79</accession>
    <name>W6YY79_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_39427</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964058">
        <property type="protein sequence ID" value="EUC42533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690953.1">
        <property type="nucleotide sequence ID" value="XM_007692763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY79"/>
    <dbReference type="GeneID" id="19123687"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39427"/>
    <dbReference type="HOGENOM" id="CLU_159433_0_0_1"/>
    <dbReference type="OrthoDB" id="3686701at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="130" mass="14679" checksum="9C0A812D8930AEFE" modified="2014-04-16" version="1">MLGGGFCRRCLGRCGVEISIAKQSLSLSLYCCRTGGEQSMYFQLCLPVWAQLPRGRCIMLLETPIASNMPRTRRFVLQIPQSRVPDCAQLAIWHNASEAPSTSTTTLFCEKKQRKFTFSNFIRPNRITQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYY5</accession>
    <name>W6YYY5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lytic polysaccharide monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_48854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC44582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="930090.W6YYY5"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_48854"/>
    <dbReference type="eggNOG" id="ENOG502S005">
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005089">
        <property type="entry name" value="CBM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF2">
        <property type="entry name" value="LYTIC POLYSACCHARIDE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
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            <end position="365"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <end position="225"/>
        </location>
    </feature>
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            <end position="240"/>
        </location>
    </feature>
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            <end position="252"/>
        </location>
    </feature>
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            <end position="297"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="311"/>
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        </location>
    </feature>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="382" mass="38059" checksum="E099676153D7CAB3" modified="2014-04-16" version="1" fragment="single">LAPLSSAHMIMANPVPFNAPSNSPLAPDGSDFPCKGPASGSAQVNEWPVGSTQSLSFSGTAVHGGGSCQMSVTTDKTPTKDSKWKVIYSIEGGCPANVKGNLDLNSGSYNGSFPFTVPQDLPTGDFTVAWTWFNKIGNREMYMNCASVSVTGGADDASGLDALPDMAIANVNVPGSCGTTKEGADYTFSNPGAFGTTAGEGPFMDLCAGTPSQPGMGRGGSGSDGAAGASLQAPAASDAGSAMPSTFRTVKTLTAPMPPVPTNPGGVMAPSACSAAPAPKPTPAQPSQGPGIAHPTAAPAPAPAPSPVTPRPSTGLAPGSGSSTGTPCSTDGQLVCSPDGTQYGLCNFGKAVMMPVAGGTKCVNGAIAKRDDYTHRNQRTAI</sequence>
</entry>
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    <accession>W6YZG9</accession>
    <name>W6YZG9_COCMI</name>
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        <submittedName>
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        </submittedName>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="64" mass="7164" checksum="81F35AC31F9E94E5" modified="2014-04-16" version="1">MTYSRLLTPRSMAVLSIISLGGGYFTLRSRTLAEKQTVRSSRDFAVSVDRSGRSRHTLIDTLQC</sequence>
</entry>
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    <accession>W6YZM8</accession>
    <name>W6YZM8_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_101892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_101892"/>
    <dbReference type="HOGENOM" id="CLU_013929_9_1_1"/>
    <dbReference type="OrthoDB" id="5420958at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11933" checksum="C53CCCA7ACEE7EE1" modified="2014-04-16" version="1">MDKASQVLAKGLPPAVPTSYRALIDYSEVPRSTLHARAQGRRSIEEKAQSQQYLSPWEEDALVKFLLQMSNLGQPVRIKFIPFLAFCVARQRSKRARPLKPPNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0A9</accession>
    <name>W6Z0A9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_101076</name>
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    <organism evidence="3 4">
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964032">
        <property type="protein sequence ID" value="EUC43335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691951.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z0A9"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_101076"/>
    <dbReference type="eggNOG" id="ENOG502SNVD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_349491_0_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="286"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="641"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="745"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="805" mass="93008" checksum="E5918DB5FAC1428A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0Q6</accession>
    <name>W6Z0Q6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal peptidase complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_38539</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPCS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964026">
        <property type="protein sequence ID" value="EUC43540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689946.1">
        <property type="nucleotide sequence ID" value="XM_007691756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0Q6"/>
    <dbReference type="STRING" id="930090.W6Z0Q6"/>
    <dbReference type="GeneID" id="19123498"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38539"/>
    <dbReference type="eggNOG" id="ENOG502S23I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089740_1_0_1"/>
    <dbReference type="OrthoDB" id="29558at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009582">
        <property type="entry name" value="Spc2/SPCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13085">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13085:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06703">
        <property type="entry name" value="SPC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC43540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="225" mass="25208" checksum="6E8FC6017B5F0FE2" modified="2014-04-16" version="1">MSATQKIAVHSLPDLKSTTDDALPNYLNSLKFKQIHTSTDIRLVLGYTAVTIAGALFYYDWKFGWEASKPFTLPAVVAYFVLNSIFTYWLWFVEKGLVYEGEGKTGKLRISSWTKKHIPIYECDVVFTPAPYASNPKQTLHIRAPMTRWFTEDGYFVAKPFQQWLASEIPVVGAADPNNVVEEIGRGSASMDNTLNLNSSNAVDILQQLKASGAKFASGEAQRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0S6</accession>
    <name>W6Z0S6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_101286</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964034">
        <property type="protein sequence ID" value="EUC43283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690205.1">
        <property type="nucleotide sequence ID" value="XM_007692015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0S6"/>
    <dbReference type="STRING" id="930090.W6Z0S6"/>
    <dbReference type="GeneID" id="19117847"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101286"/>
    <dbReference type="eggNOG" id="KOG1318">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046871_1_0_1"/>
    <dbReference type="OrthoDB" id="71302at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11398">
        <property type="entry name" value="bHLHzip_scCBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000144">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047206">
        <property type="entry name" value="bHLHzip_scCBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787:SF1">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="4">
        <location>
            <begin position="171"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="139"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC43283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="294" mass="32599" checksum="7C387942F158ACD7" modified="2014-04-16" version="1">MADTAGYPTDSKLDAHNSVHTNKRKRDTRDQGIINRPAPHNSNSDLTDQATASFLAAHNAADDDMQQQFDVHHNGGTNTASVGDTAAAALAYHQMTVPQATELQFQPQNSGDGSFGMGDHNQQQTGMQDFSLEALKAATQTGRPGQAAPSDSPPQSATHKPQVGTEEWHKVRRDNHKEVERRRRETINEGINELAKIVPGCEKNKGSILQRAVQFITQLKENEQQNIEKWTLEKLLTEQAITELSASCDKFKAECQRAWDECQIYKRACENNGILPDEIKERQENGEQTGANPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1H6</accession>
    <name>W6Z1H6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_100498</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964025">
        <property type="protein sequence ID" value="EUC43563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689922.1">
        <property type="nucleotide sequence ID" value="XM_007691732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1H6"/>
    <dbReference type="GeneID" id="19117686"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100498"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
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    <sequence length="638" mass="69336" checksum="EB43B9AD43DF6865" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6Z1P9</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000054032"/>
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</entry>
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            <taxon>Dothideomycetes</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
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                <person name="Lowry S."/>
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                <person name="Han J."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for efficient biogenesis of the 60S ribosomal subunit.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
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            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
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        <text evidence="3">Belongs to the RSA3 family.</text>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="C:preribosome, large subunit precursor"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Ribosome_Assembly_3"/>
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        <property type="entry name" value="Rsa3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28127">
        <property type="entry name" value="RIBOSOME ASSEMBLY PROTEIN 3"/>
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    </dbReference>
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        <property type="entry name" value="RIBOSOME ASSEMBLY PROTEIN 3"/>
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    </dbReference>
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        <property type="entry name" value="Rsa3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
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            <end position="73"/>
        </location>
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        <location>
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            <end position="23"/>
        </location>
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            <position position="1"/>
        </location>
    </feature>
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        <location>
            <position position="83"/>
        </location>
    </feature>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00015339"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF14615"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41629.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="83" mass="8924" checksum="3DC619FD9E4C168D" modified="2014-04-16" version="1" fragment="single">ATATPSQPSKASKPNQSSQASQASKEVFSTLYLRKLATEFADDLDKVREAPDFKASSVPMLIHALKQGETLFSGEERARVVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z217</accession>
    <name>W6Z217_COCMI</name>
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        <recommendedName>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964091">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691799.1">
        <property type="nucleotide sequence ID" value="XM_007693609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z217"/>
    <dbReference type="GeneID" id="19121534"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29575"/>
    <dbReference type="eggNOG" id="ENOG502QUEX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011125_1_0_1"/>
    <dbReference type="OrthoDB" id="441660at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051957">
        <property type="entry name" value="CRISP-LCCL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004043">
        <property type="entry name" value="LCCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331:SF8">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02970)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50820">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="3">
        <location>
            <begin position="164"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="632" mass="70755" checksum="547F4236CF6EEF3F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2P4</accession>
    <name>W6Z2P4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Matrin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_8426</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964080">
        <property type="protein sequence ID" value="EUC41924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691546.1">
        <property type="nucleotide sequence ID" value="XM_007693356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2P4"/>
    <dbReference type="STRING" id="930090.W6Z2P4"/>
    <dbReference type="GeneID" id="19126431"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8426"/>
    <dbReference type="eggNOG" id="KOG0227">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050757_1_0_1"/>
    <dbReference type="OrthoDB" id="10250970at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.2690:FF:000002">
        <property type="entry name" value="Splicing factor 3a subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052092">
        <property type="entry name" value="SF3A2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031781">
        <property type="entry name" value="SF3A2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205:SF0">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16835">
        <property type="entry name" value="SF3A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="11">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC41924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="235" mass="26984" checksum="DD31FBCD994A2457" modified="2014-04-16" version="1">MDYQNRAGSKFGGGGVASQSATNADRRERLRKLALETIDLDKDPYFFKNHVGSFECRLCLTVHQNDGSYLAHTQGRKHQTNLARRAAKEQREGKRDDVGQQGLLAGVVPKKNVIKIGRPGYRITKVRDPNTRQNGLLFQFQFPDLTPGVTPKVRIMSAYEQRVEEPDPNYQYLIVAGEPYETVAVKLQSRDIDRREGKFWFWYDEDAKEFWCQVLFKTERDERFSAVPGLAPGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3P1</accession>
    <name>W6Z3P1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_92959</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687127.1">
        <property type="nucleotide sequence ID" value="XM_007688937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3P1"/>
    <dbReference type="STRING" id="930090.W6Z3P1"/>
    <dbReference type="GeneID" id="19128176"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92959"/>
    <dbReference type="eggNOG" id="KOG1679">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="OrthoDB" id="410701at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000058">
        <property type="entry name" value="Enoyl-CoA hydratase/isomerase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF171">
        <property type="entry name" value="SD19268P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="297" mass="31796" checksum="FC34E4E15F4A8E29" modified="2014-04-16" version="1">MPFLRPAPRIIYRAIQTRTFATAQTPAINVKNIPAPHCGSIRVLSLNRPAARNAISRQLLAELSHQVNSIHDEGDNGPTRALILASDVDSSFCAGADLKERATFTQEETANFLASLRGTFTSISQLPIPTISALAAPAFGGGLELALTTHMRVFGSTTTVALPETRLAILPGAGGTYRLPAVIGLSRARDMILTGRRVAAPEAYFLGLCDRLVEVTPEVAKEEGAARKKVLEEAINLAMNICEGGPIAIRAALAAVEGCALGEKAENAAYDRVVRTKDRDEALLAFREKRKPVFKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z413</accession>
    <name>W6Z413_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_103607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964063">
        <property type="protein sequence ID" value="EUC42369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691101.1">
        <property type="nucleotide sequence ID" value="XM_007692911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z413"/>
    <dbReference type="GeneID" id="19118342"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103607"/>
    <dbReference type="HOGENOM" id="CLU_1895822_0_0_1"/>
    <dbReference type="OrthoDB" id="10502550at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886435" description="REJ domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="13222" checksum="44CFBECF4CCE5D2F" modified="2014-04-16" version="1">MLASSFTVAAIALFAPLALAQSTASSTSSSAATTSMSMSMSSMSSMSMSMVPMPTPSRADVTMAWNDGPASTSGASMSGSMGSGMMTMSDGSVMPMSTGSAMGLMNMGNMTGSAGRLDMGTGVAFLGAMLAAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z426</accession>
    <name>W6Z426_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc knuckle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964063">
        <property type="protein sequence ID" value="EUC42384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691094.1">
        <property type="nucleotide sequence ID" value="XM_007692904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z426"/>
    <dbReference type="GeneID" id="19121416"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28983"/>
    <dbReference type="HOGENOM" id="CLU_1137825_0_0_1"/>
    <dbReference type="OrthoDB" id="3694544at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="30134" checksum="F124885470C9928A" modified="2014-04-16" version="1">MDREEASKHRAVMNWLNPIPPRYPHDPPNILSLDQALQLVESVRDAESKRPRKRKATLRQNQRDCHLCGQKGHTAKDTAEDGSFKCPTRTTDAQTMSTELARLRAEFTTELAAVHQKDEQKNPLLQQSQDQNQHQNQQVQQNIYHHPRPQQQQRTLYHRHRHPQTQAAYTTALQKSNRNLPIWSVNYFELHHALQRKSGLARFVDFSGRTHFVRLYSEGLRRYVEEERESEREEEGEEREVLWPNVQVVVVGRGVGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z471</accession>
    <name>W6Z471_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688776.1">
        <property type="nucleotide sequence ID" value="XM_007690586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z471"/>
    <dbReference type="GeneID" id="19124809"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6043"/>
    <dbReference type="HOGENOM" id="CLU_2037636_0_0_1"/>
    <dbReference type="OrthoDB" id="3690679at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="139" mass="15794" checksum="CF9317849D416F9E" modified="2014-04-16" version="1">MPRKRSYFNGPGRVLGTGELIEPKRNVRKAHDMEYIPPKDAEFTMEDGNHENDVQDRTEDEEWTPESKKRKRKRIKTQRDEASTSTKKGVSDKNEQCLLKESNDNDAAVAEGLNGGGRHECSCAACKKLRGEEDKELSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4C9</accession>
    <name>W6Z4C9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Aminomethyltransferase</fullName>
            <ecNumber evidence="4 12">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 12">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_97772</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)-5,6,7,8-tetrahydrofolate = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="4 12"/>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688900.1">
        <property type="nucleotide sequence ID" value="XM_007690710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4C9"/>
    <dbReference type="STRING" id="930090.W6Z4C9"/>
    <dbReference type="GeneID" id="19129124"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97772"/>
    <dbReference type="eggNOG" id="KOG2770">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_10_0_1"/>
    <dbReference type="OrthoDB" id="10263536at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.110:FF:000002">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1400:FF:000001">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1250.10:FF:000002">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1250.10">
        <property type="entry name" value="Aminomethyltransferase fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001567">
        <property type="entry name" value="PRK00389.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF2">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006487">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="GCVT N-terminal" evidence="13">
        <location>
            <begin position="72"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="14">
        <location>
            <begin position="367"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006487-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC44603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="457" mass="49732" checksum="01F7CAA247DD2488" modified="2014-04-16" version="1">MAARKPVAALRPVANVFAPQVGRLQCPKVARYSTRTCTWPAPRPRNFTEPARQHVRWASSQAAGEQLGKTGLYELHSKYGAKFVPFGGYLMPVQYSDLSIIDSHNWTREKASLFDVGHMVQHHFSGPGAEAFLESITPSALSALPKHQSTLSTLLNSNGGIVDDTVITRLTDRFYVVTNAGCREKDTAYFKAQLDAWKSKHSDQPVEWQILDGQGLVALQGPLSSEILSRVLDDKSKKDLESLYFGQCANATIKGTDAEVLVSRGGYTGEDGFEISIPAYATEAVTQYLLDSAKDELRFAGLGARDTLRLEAGMCLYGHDLDDTTTPVEAGLSWIIGKDRRVKGGFLGDSVILQQLKKKSEGGGVSRRRVGLVVEGSPAREGAEIVNEAGEKIGNITSGCPSPTLKKNISMGYIQDGMHKAGTEVDVVVRGKKRKAVVTKMPFVPSKYFKQPANVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4U8</accession>
    <name>W6Z4U8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_25245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686694.1">
        <property type="nucleotide sequence ID" value="XM_007688504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4U8"/>
    <dbReference type="GeneID" id="19120730"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25245"/>
    <dbReference type="eggNOG" id="ENOG502SHAY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_1_1"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF31">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="25"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="396"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC46767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="420" mass="47149" checksum="8DDD14ED641AE28C" modified="2014-04-16" version="1">MAPTSYPMALAVLVPLPFDIISTVLRFWIRTKRNAWGPDDWAMLINIVRALDPQSCPFWSVSTIATLGMAWSGVGQYDATLTQSQYMNSLRWFYVFQEPWCFTLITIKCSIGFALIRIASGKKWIEYVIYISMLSCFVVMGGTGMYLFFQCMPVQKNWDTKVEGYCRERSTQTILSYAVAAVSISTDWIFATLPIFLLWDVQLDWRVKGGVMGMLGLGIFASIAPIVRLKYLIGLNDASRLLQNLSAILAWATAEMNVGMFVANLPACHPLLKHAIARFSTWSGSNSRSYSSGIFGSKKPHPGGPSASNAIDSKNKWLELDDQQQQQRPESSRTRNYLSNKGKGTGVETKIYGDLEDYGSEESLDARDDGSQKRIVKKPSLDGLQVNVQKDFRVEVSERFDQRGRGRGKEDADRVQADRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5E0</accession>
    <name>W6Z5E0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_25047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC46992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686466.1">
        <property type="nucleotide sequence ID" value="XM_007688276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5E0"/>
    <dbReference type="GeneID" id="19120697"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25047"/>
    <dbReference type="eggNOG" id="ENOG502RN2Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049199_0_0_1"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630:SF7">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39956" checksum="2146D372079A493F" modified="2014-04-16" version="1">MSTTVQTTLSEAPVEVPKFKPQPSGPKRLFRQEGLVYGDWRDDIIRDGYVVVKGAIPRDRADGYAEEMMSWLENFAGGLGFKRDDPSTVVESKMPIINEKGMCLGYGIAHETFAWSVRQEPGVVGAFEKVYDTKDLIVSFDASNMAFPNRKDLKENNPWPHQDQDPEKPGFRCLQGLVNLLPNSDNDGGLIVCKGAHLLSEEFHEQFKDEPDKIWAWTKEWYGFTKEGMKWLEDKGCEWVKLNAEPGDLLLWDSRTPHYNLSPTGDRPRFCIYTCYMPVAEASEEDLLRKKDAFYTTQSTTHWPNARHVGGLPIIRDNEPCPYNTGKPRKPVELSKRGFELTGIPYIGTLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5H6</accession>
    <name>W6Z5H6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_96595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963992">
        <property type="protein sequence ID" value="EUC45023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688438.1">
        <property type="nucleotide sequence ID" value="XM_007690248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5H6"/>
    <dbReference type="STRING" id="930090.W6Z5H6"/>
    <dbReference type="GeneID" id="19128881"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96595"/>
    <dbReference type="eggNOG" id="KOG2936">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049046_1_0_1"/>
    <dbReference type="OrthoDB" id="567237at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd08892">
        <property type="entry name" value="SRPBCC_Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="ASHA1/2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF22">
        <property type="entry name" value="LD43819P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="330" mass="36707" checksum="9A994451352BBBDD" modified="2014-04-16" version="1">MVLHNPNNWHWVNKDVSVWTREYLDKDLAQISAEKNGVTAKIDKVVSMDGDVDVSQRKGKVITIFDVKLKLEYSGKNKEGEETSGTITIPEVAHDTEEDEYVFEVDVYSEDSSKQPVKELVRSDILPQLRKSFAKLAPAIMAEHAKDIQHAPGTNPSTNFTAAKVYSSSSVNKSSSSKPEATSSQKSSSGAVVNVTTITDSAEFRTDAANLYQTFTDPQRLAAFTRAPPKNFTGAKPGGKFELFGGNVSGEFTELEEPTHIVQKWRLAQWPEGHYSTLSIWFDQNDIDAVTVMRVEWAGVPVGQEEPTKTNWEQYYVRSIKTTFGFGTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5W4</accession>
    <name>W6Z5W4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="3">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_39056</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="3"/>
    <dbReference type="EMBL" id="KI964044">
        <property type="protein sequence ID" value="EUC42944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690531.1">
        <property type="nucleotide sequence ID" value="XM_007692341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5W4"/>
    <dbReference type="STRING" id="930090.W6Z5W4"/>
    <dbReference type="GeneID" id="19123606"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39056"/>
    <dbReference type="eggNOG" id="KOG2529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032087_4_0_1"/>
    <dbReference type="OrthoDB" id="9995526at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="7">
        <location>
            <begin position="59"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="371" mass="40909" checksum="963F9CD6C21D0F28" modified="2014-04-16" version="1">MDSEGEKILEGIFAVAKPTNVSSADVLLKLQETFAPSATFAPLLRTQPKRTSKSSDQVFRLGHGGTLDPLAAGVLIVGIGRGTKQLSNYLSCSKTYETVVLFGASTDTYDCTGSITQEAGYSHVTKELVDEKLGAFRGTIQQLPPLYSALKINGIKACEYARQGKDLPRELESREMHVDECTLLEWYEPGQHDFAWPGKVEPASAPAAKIRLTVCSGFYVRSFAHDLGRACDTYSHMASLLRTRQADFTTSNPPELSSLTSTLTYADLEAGEHVWGPKLRPQLDRWVTAHPVVQGHVNGRDASVKRKTEEQQARPRQRFRGEWVASTKKERIKQQGGKFKGKWGRKLAADGEANNITSNQSMVPVINDQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6C0</accession>
    <name>W6Z6C0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 20">Serine/threonine-protein kinase Tel1</fullName>
            <ecNumber evidence="5 20">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">COCMIDRAFT_3687</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17 20">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Chromosome</location>
            <location evidence="2 20">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="5 20"/>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686135.1">
        <property type="nucleotide sequence ID" value="XM_007687945.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z6C0"/>
    <dbReference type="GeneID" id="19123128"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3687"/>
    <dbReference type="eggNOG" id="KOG0892">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000178_8_2_1"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05171">
        <property type="entry name" value="PIKKc_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000034">
        <property type="entry name" value="Serine/threonine-protein kinase Tel1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000019">
        <property type="entry name" value="Serine/threonine-protein kinase Tel1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044107">
        <property type="entry name" value="PIKKc_ATM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021668">
        <property type="entry name" value="TAN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11640">
        <property type="entry name" value="TAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01342">
        <property type="entry name" value="TAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14 20" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7 20" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11 20" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 20" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="15 20" id="KW-0779">Telomere</keyword>
    <keyword evidence="9 20" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="23">
        <location>
            <begin position="1868"/>
            <end position="2474"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="22">
        <location>
            <begin position="2588"/>
            <end position="2899"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="24">
        <location>
            <begin position="2938"/>
            <end position="2970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="173"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="2868"/>
            <end position="2926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="2871"/>
            <end position="2887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="2899"/>
            <end position="2909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU365027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EUC47267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="2970" mass="332854" checksum="38A92C645116FC65" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6C2</accession>
    <name>W6Z6C2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_5261</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC45545.1"/>
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        <property type="nucleotide sequence ID" value="XM_007689727.1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_5261"/>
    <dbReference type="eggNOG" id="KOG1238">
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    <dbReference type="HOGENOM" id="CLU_002865_6_1_1"/>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886675" evidence="5">
        <location>
            <begin position="22"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="525"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="568"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="33"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC45545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="588" mass="62996" checksum="C912DBE7310486C3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z723</accession>
    <name>W6Z723_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubulin gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Gamma-tubulin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_36688</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Spindle pole body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963981">
        <property type="protein sequence ID" value="EUC45593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687880.1">
        <property type="nucleotide sequence ID" value="XM_007689690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z723"/>
    <dbReference type="STRING" id="930090.W6Z723"/>
    <dbReference type="GeneID" id="19123089"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36688"/>
    <dbReference type="eggNOG" id="KOG1374">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2258">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006073_1_0_1"/>
    <dbReference type="OrthoDB" id="10249382at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02188">
        <property type="entry name" value="gamma_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08570">
        <property type="entry name" value="GDPD_YPL206cp_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000004">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000003">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000012">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002454">
        <property type="entry name" value="Gamma_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01164">
        <property type="entry name" value="GAMMATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="11">
        <location>
            <begin position="49"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="768"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC45593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="789" mass="88908" checksum="33927D3B3FAF38EE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8C9</accession>
    <name>W6Z8C9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_4617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687193.1">
        <property type="nucleotide sequence ID" value="XM_007689003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8C9"/>
    <dbReference type="STRING" id="930090.W6Z8C9"/>
    <dbReference type="GeneID" id="19124309"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4617"/>
    <dbReference type="eggNOG" id="ENOG502RR34">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073919_0_0_1"/>
    <dbReference type="OrthoDB" id="512662at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF4">
        <property type="entry name" value="ACETYLTRANSFERASE, GNAT FAMILY FAMILY (AFU_ORTHOLOGUE AFUA_4G09540)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="79"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="229" mass="26489" checksum="CB0B0D8969E379E3" modified="2014-04-16" version="1">MPIQVSRMTPSDIPGAITTIQLAFASDPYNLWLYPDRSKISLERNRVSLTLRCIWGISHGLFYVARDTANPGQILGCAMWLPPHPTCARQSWGEWWSGWWLWMNQVRMNAWYGRGGLSTTRYWIWKARQAEAQSELWTDAQGYYFCNIVTVLPEWQGKGVGRALMDEVLSMADREGRRAYLESSRWVPNGAIYERFGFRLVKEMECRDGDGERDAVTLYCMMREPKGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8R8</accession>
    <name>W6Z8R8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_109703</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Peripheral membrane protein</topology>
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    <comment type="similarity">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033370">
        <property type="entry name" value="COG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
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            <end position="498"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="694"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006653"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00020978"/>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40086.1"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="790" mass="88540" checksum="1AFB3C7D57206CDE" modified="2014-04-16" version="1"> </sequence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC46410.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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    </evidence>
    <sequence length="169" mass="19319" checksum="6B8686BA4228F4A2" modified="2014-04-16" version="1">MDGNQIPTSLKRNGLQTCIAIGGWSFNDPGTLKCNAHSDMVPAEANRRAFIQSLIKFMDTYGFQGVDIDWEYPAEPKSGGRKEDTDNLVLLMKEMKEQFGRRYSGSFTLTPDYWYLRGFKPAEMQRYVDWTRFMSYGLHGSWGTDAKTLGSRVRPQTDITEIEKSLKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z985</accession>
    <name>W6Z985_COCMI</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_99111</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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    </reference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="172" mass="19392" checksum="D33D748A54297FC5" modified="2014-04-16" version="1">MDPILVLSVARRLVLHLARLAWWPIAKLITLAVILLRPFYLLVTVALLPFIHLAHALFQVVSLPFTVKWLEQIETLYVFLGIAALIGSITGTTLFIMFKFLSSTLRIDAPIVPEKPVETRTAAQYRAERRAKKEEAIHHLPAITPVVLKKPAGPRRRGLLSQAIIEEEDSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9D5</accession>
    <name>W6Z9D5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase</fullName>
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            <shortName evidence="11">Hydroxymethylpyrimidine phosphate synthase</shortName>
        </recommendedName>
    </protein>
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        <name evidence="13" type="ORF">COCMIDRAFT_109183</name>
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 2 Fe(3+) + 4 H2O = L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 3-oxopropanoate + 2 Fe(2+) + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65756"/>
            <dbReference type="Rhea" id="RHEA-COMP:16892"/>
            <dbReference type="Rhea" id="RHEA-COMP:16893"/>
            <dbReference type="Rhea" id="RHEA-COMP:16894"/>
            <dbReference type="Rhea" id="RHEA-COMP:16895"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:33190"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:143915"/>
            <dbReference type="ChEBI" id="CHEBI:157692"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:65757"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 11">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the NMT1/THI5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964178">
        <property type="protein sequence ID" value="EUC40291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693182.1">
        <property type="nucleotide sequence ID" value="XM_007694992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9D5"/>
    <dbReference type="STRING" id="930090.W6Z9D5"/>
    <dbReference type="GeneID" id="19119381"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109183"/>
    <dbReference type="eggNOG" id="ENOG502QQ87">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_6_3_1"/>
    <dbReference type="OrthoDB" id="434407at2759"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13650">
        <property type="entry name" value="PBP2_THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE SYNTHASE THI11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528:SF1">
        <property type="entry name" value="4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE SYNTHASE THI11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SsuA/THI5-like" evidence="12">
        <location>
            <begin position="16"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC40291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="353" mass="38974" checksum="4CEEE62F62319E2A" modified="2014-04-16" version="1">MSTDKITFLTNWHATPYHAPVYLAQSKGYFKDEGIKVAVLEPNDPSDVTEIIGSGKVDLGFKAMIHTLAAAARGFPVQSIGSLLNEPFTGVVYLTSSGITSDFSTLKGKKIGYVGEFGKIQLDELTAYYGMSPSDYQAVRVGMNVTRSIITGEIDAGIGLENVQMVELEEWLVSQNRARDEVQMLRIDELAQLGCCCFCSILYIGNDAFIERRPDAVRAFLRACKRATDFVLAQPEQAWAEFCAAKTAMDTPTNRKIFERSFAYFSLDLQNVQRDWEKVTQYGKRLGVLDEAFTPNYTNEYLAWGLQDEAENPVGDQKKMAELQEGVKQNGGFKRLEGMTGKTVVGAAAPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA98</accession>
    <name>W6ZA98_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ThuA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964148">
        <property type="protein sequence ID" value="EUC40656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692828.1">
        <property type="nucleotide sequence ID" value="XM_007694638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA98"/>
    <dbReference type="GeneID" id="19128565"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9503"/>
    <dbReference type="eggNOG" id="ENOG502RZ2Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057383_1_2_1"/>
    <dbReference type="OrthoDB" id="3482285at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40469:SF2">
        <property type="entry name" value="GALACTOSE-BINDING DOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40469">
        <property type="entry name" value="SECRETED GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThuA-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="239" mass="26735" checksum="4FD63DACC2D5F9DB" modified="2014-04-16" version="1">MAALAPAPTPFPIFIFTKTTSYRHTSIPSGIALFQRLSAQHPHISLTTTEDSSIFTPSTLSRYRAVILLQTLGPALLSDPQISAFRDWMQQGGGVVAIHGAAAGMPEDGWWEKMIGAKFLSHPDPEIGSLVLDSEKADEHFILSGCGGRQGWKDEWYNFHEHPRENAGLEVLLRGDTKTFSGGMHGEDHPLVWCQEFEEGRVFFTALGHFDEAYEDEWFSGMVERGLFWVARREGELKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAN9</accession>
    <name>W6ZAN9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Mitochondrial escape protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_107941</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the YME2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964141">
        <property type="protein sequence ID" value="EUC40766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692727.1">
        <property type="nucleotide sequence ID" value="XM_007694537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAN9"/>
    <dbReference type="GeneID" id="19119153"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107941"/>
    <dbReference type="eggNOG" id="ENOG502QS0P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007861_1_0_1"/>
    <dbReference type="OrthoDB" id="10267654at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12433">
        <property type="entry name" value="RRM_Yme2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018850">
        <property type="entry name" value="Mt_escape_2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039627">
        <property type="entry name" value="Yme2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034260">
        <property type="entry name" value="Yme2_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32198">
        <property type="entry name" value="MITOCHONDRIAL ESCAPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32198:SF2">
        <property type="entry name" value="MITOCHONDRIAL ESCAPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10443">
        <property type="entry name" value="RNA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
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        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
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        <location>
            <begin position="195"/>
            <end position="287"/>
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    </feature>
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            <end position="57"/>
        </location>
    </feature>
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        <location>
            <begin position="606"/>
            <end position="625"/>
        </location>
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            <begin position="610"/>
            <end position="625"/>
        </location>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU367108"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40766.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="845" mass="94506" checksum="FEEE90B8DFD133CB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="148" mass="16368" checksum="B98B3B8C01081C81" modified="2014-04-16" version="1">MPRSSQKYPIDSDDDENTPLHLADKNEDEYIPLRPMSEDDDESPAASLGPDAVGDGQRVALSKQTRAILDRQLNGIPSTRNHQEFSLWPYATKRDKMAILVSSMAGLVAGAANPFISVRPLLSQSSPFPTKKSYRKTDLSIDSYFLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="4">O-methyltransferase C-terminal domain-containing protein</fullName>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">ATCC 44560</strain>
        </source>
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    </dbReference>
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            <begin position="2"/>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC40846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="115" mass="12483" checksum="AA0FEA49102E431D" modified="2014-04-16" version="1">MIIDIGGGGGGFIAMLLRAHKSLKGGIFDLPHVIEYAKSLFHSADGQFADIAAHVPVENLIGGDFSEVSHLPKCIRWSGRYIIGAMRMQDALREQQTDHLGGDAGHDKEYEVVPL</sequence>
</entry>
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    <accession>W6ZBK1</accession>
    <name>W6ZBK1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_3614</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687863.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_3614"/>
    <dbReference type="eggNOG" id="ENOG502RA14">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2139939at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044688">
        <property type="entry name" value="SCI-1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34117">
        <property type="entry name" value="STYLE CELL-CYCLE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34117:SF1">
        <property type="entry name" value="STYLE CELL-CYCLE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="343" mass="40638" checksum="44B85EE52B90D61A" modified="2014-04-16" version="1">MPRRDWTPEESRAQLPPRADQLPCSTRSHKRHHHSHRSRSPRRDGDGYRQKRTRTRSRSPERKPVDLPYKAKLLSKRQYDEYRPLFQSYLDIQKQIQLDDLDEREAKGRWKSFVSRWNRGELARGWYDPSMLRTAQETVQSYRASSAQAPARRASPSYAPKEGAEDDSDDEFGPAPPRDLARHVGHGPTIPRLDDLTYRNELRDEDRARGQSEYMDDLRYSRKADRKAQKERLDELVPRADPGSRERQLEKKRETTSTLQSFREAKESGDVEVAESDLMGDDGIDMYKKKKREQERQKNEREIRREEIARAREAERNERLAERREKESKTMEFLKQIAQERFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBY3</accession>
    <name>W6ZBY3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_3583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685977.1">
        <property type="nucleotide sequence ID" value="XM_007687787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBY3"/>
    <dbReference type="STRING" id="930090.W6ZBY3"/>
    <dbReference type="GeneID" id="19122878"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3583"/>
    <dbReference type="eggNOG" id="KOG0134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_2_1_1"/>
    <dbReference type="OrthoDB" id="72788at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF2">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE PYRROLE 2,3-DIOXYGENASE (AFU_ORTHOLOGUE AFUA_5G01450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="2">
        <location>
            <begin position="40"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="464" mass="50444" checksum="FC89BB688F96FCEF" modified="2014-04-16" version="1">MAPQDYNHGVPGLPYSTPKHDTSPGSIPPSSKQDAPVPTLFTPLTIRETTLRNRIQVAPMCQYSSASEGPSTGALTDYHIATLGHYALKGAALVFIEATGVQANGRISPNCPGLWSDSQIPALRRVSDFIKSQGAQCGIQLAHAGRKASTCAPWIAGSQKTQGGKRKVSVKADVDAAGWPTDVVGPMGGQEWAWDNLPASDENSGYWAPRALSEAEIQELVQDWAAAAQRAVKAGVDVIEIHGAHGYLIHQFLSPVTNQRTDKYGGSFENRTRLLIDIIKAIRAVIPDSMPLYLRISSTDWMEETELGKKLGSWDVESSIRLAKLLPALGVDLLDVSSGGNHPEQRINMFESKDYQTKIAAQIRSELKKENLNLFIGAVGLITEAEQAKNIVEDGGASKAGDEELAKEAQAAVKVTEGKEPLADVVLVARQFMREPEWVLRVAWQLGLDVAWPNQFLRVRFPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC45</accession>
    <name>W6ZC45_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_26773</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF alpha subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC45009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688478.1">
        <property type="nucleotide sequence ID" value="XM_007690288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC45"/>
    <dbReference type="STRING" id="930090.W6ZC45"/>
    <dbReference type="GeneID" id="19120995"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26773"/>
    <dbReference type="eggNOG" id="KOG2393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025955_0_0_1"/>
    <dbReference type="OrthoDB" id="76676at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005674">
        <property type="term" value="C:transcription factor TFIIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001096">
        <property type="term" value="F:TFIIF-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008851">
        <property type="entry name" value="TFIIF-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011">
        <property type="entry name" value="TFIIF-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="416"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="416"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="477"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="506"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="600"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="713" mass="79946" checksum="6E40069F411F771B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCB9</accession>
    <name>W6ZCB9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipocalin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_3404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685813.1">
        <property type="nucleotide sequence ID" value="XM_007687623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCB9"/>
    <dbReference type="GeneID" id="19122470"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3404"/>
    <dbReference type="eggNOG" id="ENOG502S22D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088979_2_0_1"/>
    <dbReference type="OrthoDB" id="425354at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="22809" checksum="BCD22EB2315AE1FF" modified="2014-04-16" version="1">MASPANIDMKNLVGQWTMNKSESDAFDPVLTLQGISWFIRKAVETATLTQYLRQSTVDGSDGAPTTLIEIDQVLTGGLKGSPENRTLDWTYREHTDFIFGVIRGRSRYSTLQKFQQESKETGATDEDIKYMTEGWLEETQQGDILESFMSSAAGKWISWNVWGFAESGGERKLIKKFTVRKIDTGAVVRVKMVYDYLGPLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCM4</accession>
    <name>W6ZCM4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_89808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685954.1">
        <property type="nucleotide sequence ID" value="XM_007687764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCM4"/>
    <dbReference type="GeneID" id="19127550"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89808"/>
    <dbReference type="eggNOG" id="ENOG502SBGD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_202890_0_0_1"/>
    <dbReference type="OrthoDB" id="7392499at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="53" mass="6044" checksum="C034371AB86E39E8" modified="2014-04-16" version="1">MLMASKGHFLGQIPHPIHNRSEMKAILDDESTSMHSLPVRTTGQDFLHSCRHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCS7</accession>
    <name>W6ZCS7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 17">Mevalonate kinase</fullName>
            <shortName evidence="17">MK</shortName>
            <ecNumber evidence="3 17">2.7.1.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_105918</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17065"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.36"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:17066"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="16 17">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.36" evidence="3 17"/>
    <dbReference type="EMBL" id="KI964098">
        <property type="protein sequence ID" value="EUC41541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691956.1">
        <property type="nucleotide sequence ID" value="XM_007693766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCS7"/>
    <dbReference type="STRING" id="930090.W6ZCS7"/>
    <dbReference type="GeneID" id="19118770"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105918"/>
    <dbReference type="eggNOG" id="KOG1511">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017814_1_0_1"/>
    <dbReference type="OrthoDB" id="1652964at2759"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000027">
        <property type="entry name" value="Mevalonate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290:SF2">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 17" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 17" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 17" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="14 17" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="11 17" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="13 17" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="19">
        <location>
            <begin position="165"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="20">
        <location>
            <begin position="330"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="398"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU363087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC41541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="523" mass="56890" checksum="BD82B4B43B2BA252" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCX5</accession>
    <name>W6ZCX5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_105702</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964095">
        <property type="protein sequence ID" value="EUC41596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691886.1">
        <property type="nucleotide sequence ID" value="XM_007693696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCX5"/>
    <dbReference type="GeneID" id="19118736"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105702"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_0_3_1"/>
    <dbReference type="OrthoDB" id="5376138at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000088">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF13">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="86"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="562"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="607" mass="67586" checksum="5E0288EF5C5FEAB7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDN9</accession>
    <name>W6ZDN9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Plasma membrane proteolipid 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_5223</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963981">
        <property type="protein sequence ID" value="EUC45599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687864.1">
        <property type="nucleotide sequence ID" value="XM_007689674.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19124535"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5223"/>
    <dbReference type="eggNOG" id="KOG1773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107649_6_2_1"/>
    <dbReference type="OrthoDB" id="2802411at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF116">
        <property type="entry name" value="PLASMA MEMBRANE PROTEOLIPID 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC45599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="57" mass="6263" checksum="8248E0C94E55D7F2" modified="2014-04-16" version="1">MPFTASDICKILLAIILPPVGVFLERGCGADFLINILLTILGYIPGIIHALYIIFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDQ9</accession>
    <name>W6ZDQ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_57733</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ING family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683588.1">
        <property type="nucleotide sequence ID" value="XM_007685398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDQ9"/>
    <dbReference type="STRING" id="930090.W6ZDQ9"/>
    <dbReference type="GeneID" id="19124733"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_57733"/>
    <dbReference type="eggNOG" id="KOG1973">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_195566_0_1_1"/>
    <dbReference type="OrthoDB" id="3656564at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="3"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="5"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="58" mass="6407" checksum="A041C598ABBD979F" modified="2014-04-16" version="1" fragment="single">TEPGYCFCGTPDTNDMIACDAKGCATEWFHFTCVGLTPQTVPKGKWLCDECAEKAMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEU6</accession>
    <name>W6ZEU6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_82241</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC50342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683222.1">
        <property type="nucleotide sequence ID" value="XM_007685032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEU6"/>
    <dbReference type="STRING" id="930090.W6ZEU6"/>
    <dbReference type="GeneID" id="19126017"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82241"/>
    <dbReference type="eggNOG" id="KOG0598">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_37_1"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004711">
        <property type="term" value="F:ribosomal protein S6 kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000048">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000222">
        <property type="entry name" value="Serine/threonine-protein kinase psk1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="247"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="509"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="107"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
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        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="587" mass="65479" checksum="EC405B18543CC734" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFZ6</accession>
    <name>W6ZFZ6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_86302</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIKE family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC48803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684637.1">
        <property type="nucleotide sequence ID" value="XM_007686447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFZ6"/>
    <dbReference type="STRING" id="930090.W6ZFZ6"/>
    <dbReference type="GeneID" id="19126833"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86302"/>
    <dbReference type="eggNOG" id="ENOG502S1AV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071348_0_0_1"/>
    <dbReference type="OrthoDB" id="21214at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008555">
        <property type="entry name" value="SIKE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39472">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39472:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05769">
        <property type="entry name" value="SIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="279" mass="30382" checksum="587D6ECD649A7E6A" modified="2014-04-16" version="1">MNNYSFLESSQQQAQQQQQQQQQQQHNQSRPPPSPSHSQAGSIAGSQVNGGGQNGIPMVNGLPSGGQQTDMNHLWAVVQQLSQLLEENKAQTRGIVEGVAAIQGRAALEEGGEVGGGAVPRGNGVSMREVNGEINAATQTHLQNQLTTAQSTIASLTATNTSLSALLTDYESALALLLDKLRPYAYSQTSSILALHKHYQTLLEQERSTSMSLRIEHAEWQAGLSRVAENARNALRMQGEVEAGLRGRCKELGEENRVLRRMVGWEEREDSDEEDEDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG46</accession>
    <name>W6ZG46_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964060">
        <property type="protein sequence ID" value="EUC42476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691005.1">
        <property type="nucleotide sequence ID" value="XM_007692815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG46"/>
    <dbReference type="STRING" id="930090.W6ZG46"/>
    <dbReference type="GeneID" id="19121405"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28911"/>
    <dbReference type="eggNOG" id="KOG2495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF24">
        <property type="entry name" value="NUCLEOTIDE-DISULPHIDE OXIDOREDUCTASE AMID-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="18"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="447" mass="48612" checksum="749FB2C99C8AB8FC" modified="2014-04-16" version="1">MRLTETLSSVSSSGPHRVLVVGCAYGGISAVLNLIEYSQGRARQSVYPGPDFKGARSRRGVEITVIDERDGYFHSVGAPLAHVTPKYTAHMWKRFSHLNELKQPNLHFRHGSVKNVNPEAKVAEWCDRNGQVQQQAYDYLVMATGLKRPFPAVPKSGTFEEYQRDGKAFIEKITGGDPSKYEGRRVVVIGAGAVGVEFAAEIKSYYPQIAVTLVHSRSEVLSSEPLPAEVKERARILLEEEGVSLRLGSRATITDMPNGQYTVTLANNETITADFVIDSTKKGTPTTDILPAECLNADKEVMVHQSLMFKDTIANASSHFGVGDVIAWTGIKRAGSATVMGQAAAQNIYSAILNSELDSSSEQYATTELPAWDAVIGLAVGKQCLTYDPTNGIKYGVEVMKGYFGEDLGWAANLKYLGLTDVVERADSPVEETKMTEVGIKPVSAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGE9</accession>
    <name>W6ZGE9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_103135</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EFG1/PHD1/stuA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964056">
        <property type="protein sequence ID" value="EUC42576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690905.1">
        <property type="nucleotide sequence ID" value="XM_007692715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGE9"/>
    <dbReference type="STRING" id="930090.W6ZGE9"/>
    <dbReference type="GeneID" id="19118231"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103135"/>
    <dbReference type="eggNOG" id="ENOG502QW2C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016460_0_0_1"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048315">
        <property type="term" value="P:conidium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.260.10:FF:000003">
        <property type="entry name" value="Ascospore maturation 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029790">
        <property type="entry name" value="EFG1/Phd1/StuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47792">
        <property type="entry name" value="PROTEIN SOK2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47792:SF1">
        <property type="entry name" value="PROTEIN SOK2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0183">Conidiation</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="8">
        <location>
            <begin position="318"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="104"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="443"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="528"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="545"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="567"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="699"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="766"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="831"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="840" mass="89836" checksum="5EA38D9A8518E46C" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH36</accession>
    <name>W6ZH36_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_85273</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684366.1">
        <property type="nucleotide sequence ID" value="XM_007686176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZH36"/>
    <dbReference type="GeneID" id="19126636"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85273"/>
    <dbReference type="eggNOG" id="ENOG502RPVK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011003_0_1_1"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
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        <property type="nucleotide sequence ID" value="XM_007685435.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZID9"/>
    <dbReference type="GeneID" id="19120273"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22553"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_6_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="7">
        <location>
            <begin position="367"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="8">
        <location>
            <begin position="1266"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1607"/>
            <end position="1684"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1266"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1419"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1578"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1581"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="4">
        <location>
            <position position="1298"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="4">
        <location>
            <position position="1484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC49775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1987" mass="215467" checksum="EF0DF89D5DEBA32C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIN8</accession>
    <name>W6ZIN8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Knr4/Smi1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_3814</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KNR4/SMI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686229.1">
        <property type="nucleotide sequence ID" value="XM_007688039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIN8"/>
    <dbReference type="STRING" id="930090.W6ZIN8"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_3814"/>
    <dbReference type="eggNOG" id="ENOG502QTAZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024700_0_0_1"/>
    <dbReference type="OrthoDB" id="2305498at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097708">
        <property type="term" value="C:intracellular vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070880">
        <property type="term" value="P:fungal-type cell wall beta-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009203">
        <property type="entry name" value="Knr4/Smi1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051873">
        <property type="entry name" value="KNR4/SMI1_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432:SF1">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017023">
        <property type="entry name" value="KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Knr4/Smi1-like" evidence="3">
        <location>
            <begin position="155"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="526" mass="58385" checksum="50B8A5326072D169" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJE9</accession>
    <name>W6ZJE9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_82712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683307.1">
        <property type="nucleotide sequence ID" value="XM_007685117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJE9"/>
    <dbReference type="STRING" id="930090.W6ZJE9"/>
    <dbReference type="GeneID" id="19126108"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82712"/>
    <dbReference type="eggNOG" id="KOG1840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_4_1"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF11">
        <property type="entry name" value="HET-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="278"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="874" mass="100743" checksum="5ECF614E4DC0185D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJW1</accession>
    <name>W6ZJW1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7729 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_89438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685789.1">
        <property type="nucleotide sequence ID" value="XM_007687599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJW1"/>
    <dbReference type="GeneID" id="19127477"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89438"/>
    <dbReference type="eggNOG" id="ENOG502S3AD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042319_1_1_1"/>
    <dbReference type="OrthoDB" id="2564812at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056146">
        <property type="entry name" value="DUF7729"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460:SF1">
        <property type="entry name" value="C6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24855">
        <property type="entry name" value="DUF7729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7729" evidence="3">
        <location>
            <begin position="34"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="268" mass="28537" checksum="939BEC6950C3C1A4" modified="2014-04-16" version="1">MPPLQGHHDAIRSSPPSKRALGTDPNASSGDFSVPAAFDSALSNNFTNACAKFLNNMRQNEDFKNCHPFSLLLQTSSSFFDASKSTLRITQTLDATCGANASQCKPLMDKYATQILLADACKADYDSDNPMVIQAYNGLVAYMPSYQASCLHGKDGNYCFASAVTNTTSPGDAYPYYLPVGQELPAGSRPTCNSCLKSAMGVFASYSNNASQPLAKTYASAAHQISIACGANFLDVTAAPIKSAASTTSVSLTPTITLVLMFLLYFFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK35</accession>
    <name>W6ZK35_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">hydroxymethylglutaryl-CoA lyase</fullName>
            <ecNumber evidence="3">4.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_22047</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:24404"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="4.1.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682989.1">
        <property type="nucleotide sequence ID" value="XM_007684799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK35"/>
    <dbReference type="STRING" id="930090.W6ZK35"/>
    <dbReference type="GeneID" id="19120168"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22047"/>
    <dbReference type="eggNOG" id="KOG2368">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022138_3_0_1"/>
    <dbReference type="OrthoDB" id="1905920at2759"/>
    <dbReference type="UniPathway" id="UPA00896">
        <property type="reaction ID" value="UER00863"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004419">
        <property type="term" value="F:hydroxymethylglutaryl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046951">
        <property type="term" value="P:ketone body biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07938">
        <property type="entry name" value="DRE_TIM_HMGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004283">
        <property type="entry name" value="PRK05692.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738:SF7">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="8">
        <location>
            <begin position="35"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="128"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="380" mass="40517" checksum="9E24A2159053797B" modified="2014-04-16" version="1">MSSKFLCLRSARLAARYPCHRRAFASAASSRADHVRIVEVGPRDGLQNEKQTVPLATKIDLVERLAKTGLTTIEAGSFVAPKWVPQMANSAEILEHVLSRPPPSPQPITYQWLLPNVKGLDNFLSTWQSKSQPSQDAYPTPPPSPGPVNGPDSNSSSQSEASASPSSPRHEVSIFTAATESFSQKNTNCSIAESLKRFEPTMSKAKEMNLNVRAYISVALGCPYEGPNVDPHKVAELAVSLLEMGADEISVGDTTGMGTAPKTMELLKTLNAAGIDKNDLALHFHDTYGQALVNSVVALEHGIRTFDAAVGGLGGCPYSPGATGNVATEDLVHCLHSLGANTGVDIEKLAEVGQWISEELGRPNESRAGKATLAKLRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKM7</accession>
    <name>W6ZKM7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_88406</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685429.1">
        <property type="nucleotide sequence ID" value="XM_007687239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKM7"/>
    <dbReference type="STRING" id="930090.W6ZKM7"/>
    <dbReference type="GeneID" id="19127260"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88406"/>
    <dbReference type="eggNOG" id="ENOG502SUA0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085444_0_1_1"/>
    <dbReference type="OrthoDB" id="5416589at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000171">
        <property type="term" value="F:ribonuclease MRP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034965">
        <property type="term" value="P:intronic box C/D snoRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000294">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, RNase MRP-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014612">
        <property type="entry name" value="Pop7/Rpp20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020241">
        <property type="entry name" value="RNase_P/MRP_Pop7_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28256">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28256:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12328">
        <property type="entry name" value="Rpp20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="243"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC48044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="287" mass="30566" checksum="F6A86AE0114E0048" modified="2014-04-16" version="1">MAGKKRSVNGQVKAQTQSASAAQDITMTDATPPCGQPQPPLSKTTSSPSTTAASKEKATVPQKPKKEGQTNSKPPAQPSTHHTTTRSKRQKLAKLPLNTKISKRPLLHPALPTPFASSQHPKVLYITASSPYISALKRVRKLLAQTSQRHKQSVSAQEKALGRARFAEANGRLDARTVEREIAGEAARKGGADGAAGAGEQVYLKATGRAIPRALEIALYFQTEADCRVRIDMGSVSAVDDVEVSVDGEQQQQGREEGGGGDDNDDDEIPETRLRTVSSVSVSIGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKZ9</accession>
    <name>W6ZKZ9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_21751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682661.1">
        <property type="nucleotide sequence ID" value="XM_007684471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKZ9"/>
    <dbReference type="GeneID" id="19120116"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21751"/>
    <dbReference type="eggNOG" id="ENOG502R8EY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1669077_0_0_1"/>
    <dbReference type="OrthoDB" id="3782326at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="159" mass="18039" checksum="B6152A3BAF8B1DA2" modified="2014-04-16" version="1">MTGVSVTSTAVSFLNKLRGKSNPYEKAHHTRSNITSPNDTTNQPRNIVPQNDLLAEAREAAGLDRVTGRRRTHVAVQTPHQQQLAVHGTHQTPAEQKAAYLAWAAQRPQERGQPYGSYEEFVREMIEKRDGRRDPAGGLSSYYAPERRVEEYYYQAMRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL47</accession>
    <name>W6ZL47_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_81264</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">TFIIA is a heterodimer composed of the large TOA1 and the small TOA2 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682764.1">
        <property type="nucleotide sequence ID" value="XM_007684574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL47"/>
    <dbReference type="STRING" id="930090.W6ZL47"/>
    <dbReference type="GeneID" id="19125836"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81264"/>
    <dbReference type="eggNOG" id="KOG3463">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112964_3_1_1"/>
    <dbReference type="OrthoDB" id="586585at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000979">
        <property type="term" value="F:RNA polymerase II core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060261">
        <property type="term" value="P:positive regulation of transcription initiation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.190:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.18.10:FF:000003">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009415">
        <property type="entry name" value="Hum_TFIIA_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="11">
        <location>
            <begin position="65"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00063181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC50795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="113" mass="13060" checksum="27A5E0731473ED48" modified="2014-04-16" version="1">MATDNTKYYELYRRSSLGGSLTDTLDHLITERRIEPQLAMKILANFDRAVADVLSEKVKARLTFKGHLDTYRFCDDVWTFIIKDINFKLDNTHQIHADRVKIVSCNAKRPGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLS0</accession>
    <name>W6ZLS0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">T-complex protein 1 subunit eta</fullName>
            <shortName evidence="9">TCP-1-eta</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-eta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_87496</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooligomeric complex that forms two stacked rings.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685090.1">
        <property type="nucleotide sequence ID" value="XM_007686900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLS0"/>
    <dbReference type="STRING" id="930090.W6ZLS0"/>
    <dbReference type="GeneID" id="19127079"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87496"/>
    <dbReference type="eggNOG" id="KOG0361">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_7_3_1"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03340">
        <property type="entry name" value="TCP1_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000022">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000006">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012720">
        <property type="entry name" value="Chap_CCT_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02345">
        <property type="entry name" value="chap_CCT_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="525"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="561" mass="61131" checksum="2BF8DBB6F1A0A018" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM75</accession>
    <name>W6ZM75_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Eukaryotic translation initiation factor 2 subunit gamma</fullName>
            <ecNumber evidence="2">3.6.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_97565</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="2"/>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688799.1">
        <property type="nucleotide sequence ID" value="XM_007690609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM75"/>
    <dbReference type="STRING" id="930090.W6ZM75"/>
    <dbReference type="GeneID" id="19129084"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97565"/>
    <dbReference type="eggNOG" id="KOG0466">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027154_0_1_1"/>
    <dbReference type="OrthoDB" id="1045173at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990856">
        <property type="term" value="F:methionyl-initiator methionine tRNA binding"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
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    </dbReference>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="EFTu-like_2"/>
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        <property type="entry name" value="eIF2G"/>
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        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
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        <property type="entry name" value="eIF2g_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044128">
        <property type="entry name" value="eIF2g_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003077">
        <property type="entry name" value="PRK04000.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
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    </dbReference>
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        <property type="entry name" value="ELONGATNFCT"/>
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    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
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        <location>
            <begin position="70"/>
            <end position="278"/>
        </location>
    </feature>
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            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
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            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00074422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC44671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="500" mass="54401" checksum="A2577B1899C37BFA" modified="2014-04-16" version="1">MESESDNDFRDDKSVSEHEEVEEIKPKSALKKGREPAPVVERPELPEQPDPSTLDVSTLSPLSPEIISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNITIKLGYANAKIYQCDNSECPRPTCYRSYKSEKEVDPPCEREGCGGRYRLKRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLNHIIILQNKVDLMREDSAAAHYESILKFIRGTVADGSPIVPISAQLKFNIDAINEQLISKIPVPVRDFSAKPHMIVIRSFDVNKPGAEIDELKGGVAGGSILTGVLKLGDEIEIRPGIVSKDSAGKIQCKPIFSRVVSLFAEHNDLKFAVPGGLIGVGTRVDPTLCRADRLVGFVLGLRGHLPNIYTELEVNYFLLRRLLGVKTADGKQAKVAKLAKNEVLMVNIGSTATGAKVVAVKADAARLSLTSPACTEIGEKVALSRRIEKHWRLIGWANIVAGNILQPIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZML1</accession>
    <name>W6ZML1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_97129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963996">
        <property type="protein sequence ID" value="EUC44826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZML1"/>
    <dbReference type="GeneID" id="19128992"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97129"/>
    <dbReference type="HOGENOM" id="CLU_1061691_0_0_1"/>
    <dbReference type="OrthoDB" id="3784793at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="262" mass="30135" checksum="BC75E8E6B7F44A3D" modified="2014-04-16" version="1">MPFHDENWEEWQRDCDTFPAYSDYLLGPDLRLVVTQEPGLHPVLYPAPMPQPIQYTRNVQSRSQIPRALTRSDLETNTLPGGQYALHRRESGDHLGNDSSNKTRTLIDPPIFLQHPRTLPEVQEQSRQQACIPTQMQLVSLPLLSSSSPQVVEDNHPSQLVSQSAWQPPVLPHTEFFVPQVSIQLRMRINSYLPQVWNCIRVTGDKSEPISADDLHRRNRAQQWLTSFKTNLPVEGRPYVSWVLRWMYSEHVAGRDPLVSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN83</accession>
    <name>W6ZN83_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963992">
        <property type="protein sequence ID" value="EUC45036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688431.1">
        <property type="nucleotide sequence ID" value="XM_007690241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN83"/>
    <dbReference type="GeneID" id="19123194"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37179"/>
    <dbReference type="eggNOG" id="ENOG502R8TE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_363282_0_0_1"/>
    <dbReference type="OrthoDB" id="3760848at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="771" mass="86216" checksum="F07FF5C61BF4DCF1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP71</accession>
    <name>W6ZP71_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963985">
        <property type="protein sequence ID" value="EUC45406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688111.1">
        <property type="nucleotide sequence ID" value="XM_007689921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZP71"/>
    <dbReference type="STRING" id="930090.W6ZP71"/>
    <dbReference type="GeneID" id="19128713"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95708"/>
    <dbReference type="eggNOG" id="ENOG502QPJI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057759_0_0_1"/>
    <dbReference type="OrthoDB" id="550558at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
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            <end position="270"/>
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    </evidence>
    <sequence length="329" mass="37388" checksum="340B7A68FAF18928" modified="2014-04-16" version="1">MDPLLAAAETAAADLARTPSPPNTPPSAATLPPSRLWAIGDIHLSFKGNREALEKLVPHPHDDLILCGDVGETAEHCRMAFTKAKECFKDVFWVPGNHELYTLPANKEDGARGEAKYMECVEIAREFGIFTPEDDYVLWEGEGGPCLIAPIFTLYDYSFRPDSVKLQDALAWAREQDIEATDEHLLHPDPYSSRIEWCNALVDKTEKKLEAAVAAHPDIPLIIVGHWPLREDLVKLTKVPRFSLWCGTKRTKDWHSRFNAKVVVSGHLHIRRTDWIDNTRFEEVSLGYPRQWHNCVEHGLDINDLLREILPGPRTPPEGERRTIWRHFG</sequence>
</entry>
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    <accession>W6ZQZ1</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:establishment of cell polarity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Actin interacting protein 3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SRCIN1"/>
    </dbReference>
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    </dbReference>
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    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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        <location>
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    </feature>
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        <location>
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        </location>
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        </location>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1007" mass="109820" checksum="F984223D65ECA006" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">ATCC 44560</strain>
        </source>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="39"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
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            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46326.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
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                <person name="Salamov A."/>
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                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <begin position="925"/>
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        <source>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="990" mass="108352" checksum="A831732893EBA044" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6ZTX2</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887081" evidence="1">
        <location>
            <begin position="20"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="219" mass="22453" checksum="6E22A9EDF35C53FC" modified="2014-04-16" version="1">MGFKKNLFCAGAFALGALAAPLPDCPDRAPATGPTALTAATLIAIAPKTESCAGADFPEECADASKAATALNSAFKTYKITSKGEQAAIVAYELFESGDFKYNKNHFPGRPGQGTRMMAMPNYVEQYATSVAGADAVAKAKAAGGDAGLVAVLALVNSDDAKSFGSAAWFVSTVCSAEVRAGLAAATKDGWDKFLSECVETPADPARDPAWTAAIANIK</sequence>
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<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUL4</accession>
    <name>W6ZUL4_COCMI</name>
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        <alternativeName>
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        </alternativeName>
        <alternativeName>
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        </alternativeName>
        <alternativeName>
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        <alternativeName>
            <fullName evidence="10">eIF2B GDP-GTP exchange factor subunit epsilon</fullName>
        </alternativeName>
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            <taxon>Pleosporomycetidae</taxon>
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        </lineage>
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    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="11">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682081.1">
        <property type="nucleotide sequence ID" value="XM_007683891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUL4"/>
    <dbReference type="STRING" id="930090.W6ZUL4"/>
    <dbReference type="GeneID" id="19120019"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21211"/>
    <dbReference type="eggNOG" id="KOG1461">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012507_1_0_1"/>
    <dbReference type="OrthoDB" id="424572at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04197">
        <property type="entry name" value="eIF-2B_epsilon_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05787">
        <property type="entry name" value="LbH_eIF2B_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11558">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000100">
        <property type="entry name" value="translation initiation factor eIF-2B subunit epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035543">
        <property type="entry name" value="eIF-2B_epsilon_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044123">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="13">
        <location>
            <begin position="527"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="686"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="691"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC51219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="709" mass="79327" checksum="AC641E63E77A52C1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWW3</accession>
    <name>W6ZWW3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_87655</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685170.1">
        <property type="nucleotide sequence ID" value="XM_007686980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWW3"/>
    <dbReference type="GeneID" id="19127109"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87655"/>
    <dbReference type="eggNOG" id="KOG1807">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001066_2_0_1"/>
    <dbReference type="OrthoDB" id="409395at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001366">
        <property type="entry name" value="ATP binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057373">
        <property type="entry name" value="ZNFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF341">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25396">
        <property type="entry name" value="ZNFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZNFX1" evidence="5">
        <location>
            <begin position="172"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="3">
        <location>
            <begin position="358"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="4">
        <location>
            <begin position="749"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1095"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1098"/>
            <end position="1114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1227" mass="137815" checksum="1BB9DAEDC8592620" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX83</accession>
    <name>W6ZX83_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_34137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685034.1">
        <property type="nucleotide sequence ID" value="XM_007686844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX83"/>
    <dbReference type="GeneID" id="19122491"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34137"/>
    <dbReference type="HOGENOM" id="CLU_180185_0_0_1"/>
    <dbReference type="OrthoDB" id="10342938at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="72" mass="7916" checksum="F245DC056FE88E3F" modified="2014-04-16" version="1">MPLGREHLCSAAIRWLHIRTVCNIPWAPLAALRVCVAIGGYGLAVATPNLPQHGVHRCMHRWIAPVTRAFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W7A155</accession>
    <name>W7A155_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683629.1">
        <property type="nucleotide sequence ID" value="XM_007685439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A155"/>
    <dbReference type="GeneID" id="19120278"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22569"/>
    <dbReference type="HOGENOM" id="CLU_079393_0_0_1"/>
    <dbReference type="OrthoDB" id="3684309at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="305" mass="34046" checksum="DFFDC019E884BE6D" modified="2014-04-16" version="1">MANPPYFDRNSMMHHPPDSSGPRYLNGSNVTEPDSQWPVFHQTTSSPMLRGYNQPPCSFSASLELPASLHQAESQSCPRITRNPSTSSSYAQFPVNNSMRRSISQFSSMSSSQHAHGYNMTQAPRGSFDGSLPLEMTRSYSSTSDNPETANQSPSVHLALTPADWHTGQQFAFTPEGLNQCTTTGPSTQYQYELDDNFGIGNGSGDQSLEWKTHTNNYRPSNMPNYDSYLGIQLNYALLPFPMDALGRTWAYEYPCCGLHHGPNISYQDHYFPSQSSLDYTMALDQISPLAVFSDLRPYTWPSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1J5</accession>
    <name>W7A1J5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Elongation factor Tu</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_83420</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683547.1">
        <property type="nucleotide sequence ID" value="XM_007685357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A1J5"/>
    <dbReference type="STRING" id="930090.W7A1J5"/>
    <dbReference type="GeneID" id="19126253"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83420"/>
    <dbReference type="eggNOG" id="KOG0460">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_0_0_1"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000003">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF36">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="51"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="443" mass="49019" checksum="E96448625BBD0D8A" modified="2014-04-16" version="1">MSSFSKVFLRTSRAAVQYQRGISPVQNALGAQGTSRWMNGVRNYAAFTRDKPHVNIGTIGHVDHGKTTLTAAITKRQAEKGFAKYLDYGSIDKAPEERKRGITISTAHIEYQTENRHYAHVDCPGHADYIKNMITGAANMDGAIIVVAASDGQMPQTREHLLLARQVGVQKIVVFVNKVDAVEDKEMLELVEMEMRELLSSYGFEGDETPIVMGSALCAIENRQPEIGVTKIDELLEAVDSWIPTPQRETDKPFLMAVEDVFSIAGRGTVVSGRVERGILKRDAEVELVGKGTAPIKTKVTDIETFKKSCEESRAGDNSGLLLRGVKRDEVRRGMVVSVPGQVKAHKKFLVSMYVLSKEEGGRHTGFGENYRPQMFIRTADESCALFWPEGTEDAHEKLVMPGDNVEMVCELHAPHVLETGQRFNMREGGRTVATGLVTRVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2E6</accession>
    <name>W7A2E6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_82530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683319.1">
        <property type="nucleotide sequence ID" value="XM_007685129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2E6"/>
    <dbReference type="STRING" id="930090.W7A2E6"/>
    <dbReference type="GeneID" id="19126073"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82530"/>
    <dbReference type="eggNOG" id="ENOG502QSAH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040959_2_1_1"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24142">
        <property type="entry name" value="ACL4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="348"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="379" mass="41861" checksum="550F016F379E69E4" modified="2014-04-16" version="1">MAKTKPADRKGKKSAKSNVKSGASKPKVSAEDLLIQAATLLQTSQPEEALVAAQRALNLVQPGSSKPSAAALPALNLLGEINVELGDPDSAREAFQAAIIIDPEGAHDGAEKFLWMAQLNEEGGAESVRWFEKGIEVLKREIGGLEGKTGKNNEIAELVEEKRQKIANSLCGIAEVYMTDLSWEEDAEARCDAAVTEALLFAPENPEPLQTLASIRISQLKPDEARSALRRSMELWKDLDPDDAKVPDYSLRISLSRLLMEAEMEDEAIEVLERLVGENDGSVEAWYLGGWCLHLLAGKQKAKGEEKVTTSLLRASRDWLENCLKLYAMLEYEDERLKEHADELLRELNDVLGPSTGAEEEEDEWEEDDGDEDEDMDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3D2</accession>
    <name>W7A3D2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_22123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683008.1">
        <property type="nucleotide sequence ID" value="XM_007684818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3D2"/>
    <dbReference type="STRING" id="930090.W7A3D2"/>
    <dbReference type="GeneID" id="19120190"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22123"/>
    <dbReference type="eggNOG" id="KOG1872">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017549_2_0_1"/>
    <dbReference type="OrthoDB" id="333239at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02657">
        <property type="entry name" value="Peptidase_C19A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16104">
        <property type="entry name" value="Ubl_USP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="109"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="391"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="582" mass="64881" checksum="75AF1BE4F3AC6019" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W7A461</accession>
    <name>W7A461_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EKC/KEOPS complex subunit CGI121</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">EKC/KEOPS complex subunit cgi121</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_81037</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the CGI121/TPRKB family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682788.1">
        <property type="nucleotide sequence ID" value="XM_007684598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A461"/>
    <dbReference type="STRING" id="930090.W7A461"/>
    <dbReference type="GeneID" id="19125787"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81037"/>
    <dbReference type="eggNOG" id="KOG4066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065847_1_0_1"/>
    <dbReference type="OrthoDB" id="329139at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2380.10">
        <property type="entry name" value="CGI121/TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013926">
        <property type="entry name" value="CGI121/TPRKB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036504">
        <property type="entry name" value="CGI121/TPRKB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840">
        <property type="entry name" value="CGI-121 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840:SF10">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08617">
        <property type="entry name" value="CGI-121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143870">
        <property type="entry name" value="PF0523-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="221" mass="24262" checksum="E15533956922DCF5" modified="2014-04-16" version="1">MASVRTFQLPHYHAYPVHVALFKDVVNASHLRRQLLDANPHFDYAFLDASMIISPQHLLSATFIALHNFLTSRPKTRTPHSELVFRLSPNNNIGESYKKFGISDSSTTIIAVKLPLSASAPDGTYVKDESITNQTVSAHLSNVVHGSSIEITDNGQELGFFCQLDKVRKVYKLASADRASQSNTTTTTTKQANGDNHGNDSQDEKAYIESLVLGTMALKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLG0</accession>
    <name>W6YLG0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_41555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964204">
        <property type="protein sequence ID" value="EUC40047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693426.1">
        <property type="nucleotide sequence ID" value="XM_007695236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLG0"/>
    <dbReference type="STRING" id="930090.W6YLG0"/>
    <dbReference type="GeneID" id="19124078"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41555"/>
    <dbReference type="HOGENOM" id="CLU_1390111_0_0_1"/>
    <dbReference type="OrthoDB" id="4151048at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="23128" checksum="404177F63B4ED193" modified="2014-04-16" version="1">MQRSRQRVKQACNRCRFKKTKRVCNKCRKDNVLCDYSLDVDHQRDKRSMVVLLEEQNKRLRDTVQMLYECIRTGRNIPALPARSPGDDRPLLQDIVAYVDTFPVCKETTSDQFQHQVTLLSTTPTFSLLQPQPEASSLLSLAASELQQSSFMAPPMQLDLPLTEYDVAQEDHDLLGSRLDLQEFSSFPGVDPAEAAALRRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLJ4</accession>
    <name>W6YLJ4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zygote-specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_109719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964201">
        <property type="protein sequence ID" value="EUC40077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693411.1">
        <property type="nucleotide sequence ID" value="XM_007695221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLJ4"/>
    <dbReference type="STRING" id="930090.W6YLJ4"/>
    <dbReference type="GeneID" id="19119493"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109719"/>
    <dbReference type="eggNOG" id="ENOG502S6ZF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166294_1_0_1"/>
    <dbReference type="OrthoDB" id="10063670at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475">
        <property type="entry name" value="ZYGOTE-SPECIFIC CLASS V COPY B GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475:SF1">
        <property type="entry name" value="ZYGOTE-SPECIFIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012249297" description="Zygote-specific protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="7857" checksum="C7B9BFE2885692FA" modified="2014-04-16" version="1">MALSILIATIVFALASPISAGPAGYGLCQAGCSAIVMACYSAAGFTWGATLGASAPASIIACNTAFGTCQAACAAVLLTPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMK4</accession>
    <name>W6YMK4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964159">
        <property type="protein sequence ID" value="EUC40507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692966.1">
        <property type="nucleotide sequence ID" value="XM_007694776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMK4"/>
    <dbReference type="GeneID" id="19128809"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9622"/>
    <dbReference type="HOGENOM" id="CLU_1030527_0_0_1"/>
    <dbReference type="OrthoDB" id="10438223at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="270" mass="30351" checksum="94BBBF37C42AF01C" modified="2014-04-16" version="1">MQAIKKMLPKRDRSEPTLQPKNNALLPRLIHNKKSKIKKHICHLLKPLRIGFLLESFNNPNLPLIILRPPTPMWEMYNVEERLFDRSGDNFVLKKSKARANFKQEGNRMLPVPVPKLEDLLMSGDEGEDEAVEAGTVYSISIDTSTFLQLYTPVSSPTPIDSPTPIKTPTPIEIPTPIETPTPPPILCNVFRPRILTVTPQRNIRMANGVPFDSKLCKSFCRSLGTCASYGVTRPFCELYALPVAGVVWTGDTNETVTNAVYTFYDLQCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YML9</accession>
    <name>W6YML9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_108604</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964158">
        <property type="protein sequence ID" value="EUC40527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692961.1">
        <property type="nucleotide sequence ID" value="XM_007694771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YML9"/>
    <dbReference type="GeneID" id="19119276"/>
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            <end position="58"/>
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    <sequence length="537" mass="57867" checksum="211C43D4A2AF3891" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNP4</accession>
    <name>W6YNP4_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="2" type="ORF">COCMIDRAFT_107360</name>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        </location>
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        </source>
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            <dbReference type="EMBL" id="EUC40992.1"/>
        </source>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="41833" checksum="80977FC6A07F0B63" modified="2014-04-16" version="1">MDQQKRSPPYEGHSSGSEARQLTPGAKKRPSRAGTRSVTTLTAAQLERKRANDREAQRAIRQRTKDHIDTLERQVRDLTAQLENNSSTKMMDLIRRNEELEQENGMLRARLSHAVSTLGVPEQGAGAPSPSDRVQMLSQPRRMSTGTARSAHSVPEIATPVSQPAHWQPQHTYAQHVSSPHVDTPPAMGEVQAPQHEAVRWSPHPGHPQQQQQPQQQQPQQHHQVSMPVQDPSVHAVEQPSMSYPSPYVMESNARAMSYPLENASMVTSQPMPMSGYGTPTSHPSPHTSEYQRHMSVPMHHQSVQGQAPAQHQQHHTSAPYGSYAVGPQQGYPPQVSHGGEMPMMHAQHGQSQMMNEQGQHIMYQPYQSNMKVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPX6</accession>
    <name>W6YPX6_COCMI</name>
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            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
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        </alternativeName>
    </protein>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693835.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6YPX6"/>
    <dbReference type="GeneID" id="19127264"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8843"/>
    <dbReference type="eggNOG" id="ENOG502QPT5">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031468_10_3_1"/>
    <dbReference type="OrthoDB" id="73846at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Probable 2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="6PGD_dom2"/>
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        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="7">
        <location>
            <begin position="35"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="8">
        <location>
            <begin position="297"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="225"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC41447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="470" mass="52235" checksum="AE918BF120A733E3" modified="2014-04-16" version="1">MEDKSLDIKDEPAASPTSRNTADFYRAKPVVDRRIHIMGIGNVGSFIAHTLRGIPNPPPVTLLFPRWERLKEWNDSPKKLTLITDGDVEVQEGYDAELAIPRIRYHGKEVGLDASSTETAGDVTILEGESTEPISSLIICSKAPYVLQGLSSVKHRLHKDSVVLFLQNGMGIVEEVNREIFPDPATRPHYMLGINSHGMHTSPDGQFTTVHAGFGTISLGILPHERDRQPDSPYMPKPKFTAPKDSPPVYPGPPDELNSEYPPPSSAKFSFTPNQRHLLRTLLRTPVLSATSFSPPDLLQMQLDKLAVNCIINPLTVLLDARNGAILNNYALTRTMRLLLSEISLVIRSLPELQYIPNVQQRFDPGRLETVVVAVANLTRDNVSSMLADTRKGMQTEIDYINGWVVKRGEELGIRCAMNYMIMQLVKGKRLVVQHEIDEGVPLVKPKQARADTELDVREGVAKAIEKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPY4</accession>
    <name>W6YPY4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964102">
        <property type="protein sequence ID" value="EUC41457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692035.1">
        <property type="nucleotide sequence ID" value="XM_007693845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPY4"/>
    <dbReference type="STRING" id="930090.W6YPY4"/>
    <dbReference type="GeneID" id="19123868"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40392"/>
    <dbReference type="eggNOG" id="ENOG502QQFN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_1_0_1"/>
    <dbReference type="OrthoDB" id="58297at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47562">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47562:SF2">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="32"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="269" mass="29522" checksum="19581C0B6C8BB22C" modified="2014-04-16" version="1">MLITETHKDVPTEAGGDMRIFIFHPSIPNYPKARFPGVVVFSEIYQVTGPVARFARQIASQGYIVAAPSSYHEFTGPEPLAYDVPGTDKGNEWKITKTVQAYDEDASLSVDTLLAMPTCNGRIGATGMCLGGHLAYRCALDSRVSAAICYFATDIHSSTLGKGKKDDSLARCKDIKGELVMIFGKMDTHVPPAGRDLIRKSLHEAGVTFSFYEPAWAQHAFIRDELSKGRYDAALSGICFEMLKELFNRTLRSDRGPRSGGDVEIEDVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ73</accession>
    <name>W6YQ73_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_105826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964097">
        <property type="protein sequence ID" value="EUC41562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691937.1">
        <property type="nucleotide sequence ID" value="XM_007693747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ73"/>
    <dbReference type="GeneID" id="19118755"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105826"/>
    <dbReference type="eggNOG" id="ENOG502TDD3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1461045_0_0_1"/>
    <dbReference type="OrthoDB" id="2561193at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="196" mass="22359" checksum="3C2226A566D61220" modified="2014-04-16" version="1">MARNTYSAFQKHLLFFSTPTTPPRLTFKSALRAGVSLGLDFPVAVLLSVSLRILYAPFPFFWSPIIVDRIPASSHRTQLENATLPQGKTNYTCSELLSLLQRSGNGGRKKAWFSHKIDQGHIVGFWTMAANTRSHTVSKEDVERFQQGNWEDAVVERRRGRHDVLPLWRGGPIWTGGHSWAVRRILKIRVYETKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQV4</accession>
    <name>W6YQV4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_10108</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964227">
        <property type="protein sequence ID" value="EUC39898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693582.1">
        <property type="nucleotide sequence ID" value="XM_007695392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQV4"/>
    <dbReference type="GeneID" id="19117800"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10108"/>
    <dbReference type="eggNOG" id="ENOG502SIF7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070647_1_1_1"/>
    <dbReference type="OrthoDB" id="5329488at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF10">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889119" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="9">
        <location>
            <begin position="19"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC39898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="251" mass="27412" checksum="3D25093E849F9823" modified="2014-04-16" version="1">MFRFTELVLVAATWSLAAAHTVMVYPPWRGNNIHTNGTLSPTDPTIPDGSLGINYHKDTDSYGFPYGMQWMYPCGGMPTSRNRTKWPLKGGAVSIQPGWFPGHALAQIYINMGYGNEPLNYSHTMLPVFQITGPTNQEYGGQFCLPQVPLPANYTPKVGDNATIQVIELAQHGAALYNCADITFAEPGDAEIPEVNATNCRNTTEPDQKIGFQVLYATTSSRAQHTIVVNGYASILVPAMLAAASWLTWVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRD2</accession>
    <name>W6YRD2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MIP18 family-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_39862</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964076">
        <property type="protein sequence ID" value="EUC42012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691457.1">
        <property type="nucleotide sequence ID" value="XM_007693267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRD2"/>
    <dbReference type="STRING" id="930090.W6YRD2"/>
    <dbReference type="GeneID" id="19123763"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39862"/>
    <dbReference type="eggNOG" id="KOG3381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075876_1_0_1"/>
    <dbReference type="OrthoDB" id="2746at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000007">
        <property type="entry name" value="Cytoplasmic protein required for cell viability"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039796">
        <property type="entry name" value="MIP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIP18 family-like" evidence="4">
        <location>
            <begin position="73"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="199" mass="21799" checksum="77647EC14690B3A8" modified="2014-04-16" version="1">MELDKDNANPTILNPSDLPSRRSDAAGKRQHHPGSGLFDDLIPRYTYLVDPLDDPVSPADWDSDDTHDDPIDEQEIYDLISTICDPEHPLSLGSLSVVNLPDIHILPPASPLSNISTVVVEITPTITHCSLATVIGLGVRVRLEQALPPRFRVDVRIKKGTHSTDEQVNKQLGDKERVAAALENGTLMGVLKKMLSTCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRF1</accession>
    <name>W6YRF1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_109471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964189">
        <property type="protein sequence ID" value="EUC40185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693301.1">
        <property type="nucleotide sequence ID" value="XM_007695111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRF1"/>
    <dbReference type="GeneID" id="19119440"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109471"/>
    <dbReference type="HOGENOM" id="CLU_2037619_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="121" mass="13488" checksum="26282698CB28ABFA" modified="2014-04-16" version="1">MQGCGERLIQYTWSFAGVSSHEGRPCEAPLHRKPEEIPYRAVVRDTWRIYGAPDRTYSRPQQSPCVSLALTYLVLPYTSHTCDVVRDIDIVLCPKCSCASKPYLSPAPHPGLAPPHQHNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRF7</accession>
    <name>W6YRF7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_109447</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964188">
        <property type="protein sequence ID" value="EUC40195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693290.1">
        <property type="nucleotide sequence ID" value="XM_007695100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRF7"/>
    <dbReference type="STRING" id="930090.W6YRF7"/>
    <dbReference type="GeneID" id="19119434"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109447"/>
    <dbReference type="eggNOG" id="ENOG502RXDV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007003_7_1_1"/>
    <dbReference type="OrthoDB" id="25921at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="568" mass="63607" checksum="4001AFB502E12DBA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRL5</accession>
    <name>W6YRL5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_104425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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            <end position="31"/>
        </location>
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        </location>
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            <end position="410"/>
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            <begin position="511"/>
            <end position="549"/>
        </location>
    </feature>
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        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="528"/>
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    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42087.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="627" mass="69268" checksum="FA0F63178CAFF989" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="6">Adenylate kinase</fullName>
            <ecNumber evidence="6">2.7.4.3</ecNumber>
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        <alternativeName>
            <fullName evidence="6">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
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        <name evidence="6" type="primary">ADK1</name>
        <name evidence="10" type="ORF">COCMIDRAFT_30351</name>
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    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <text evidence="6">Predominantly mitochondrial.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the adenylate kinase family. AK2 subfamily.</text>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001381">
        <property type="entry name" value="PRK00279.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011100">
        <property type="entry name" value="PRK14527.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="9">
        <location>
            <begin position="170"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="6">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="6">
        <location>
            <begin position="169"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="52"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="99"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="128"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="179"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
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        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC40765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="276" mass="29983" checksum="BEB5849BFC7CCDC3" modified="2014-04-16" version="1">MAPLTDTVVDDLKSTVNRLEKRIAELENKLSGHGGQSSSQESIRMILMGPPGAGKGTQAPRIKEKFCACHLATGDMLRAQVAAKTALGREAKKIMDAGGLVSDEIMINMIKTELESNQECAKGFILDGFPRTVTQAEKLDGMLAATQKPLQHAVELQIDDGLLVSRITGRLVHPASGRSYHKIFNPPKTPMTDDITGEPLIQRSDDNAETLKKRLATYHAQTAPVVAYYQKTGIWKPIDASQEPGQVWKSLLKVFDNKALIGGQSGSLLNKIGLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT77</accession>
    <name>W6YT77_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-rRNA-processing protein PNO1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Pre-rRNA-processing protein pno1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_107829</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964138">
        <property type="protein sequence ID" value="EUC40800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692680.1">
        <property type="nucleotide sequence ID" value="XM_007694490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT77"/>
    <dbReference type="STRING" id="930090.W6YT77"/>
    <dbReference type="GeneID" id="19119127"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107829"/>
    <dbReference type="eggNOG" id="KOG3273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064992_0_2_1"/>
    <dbReference type="OrthoDB" id="1932641at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042255">
        <property type="term" value="P:ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd22391">
        <property type="entry name" value="KH-I_PNO1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22392">
        <property type="entry name" value="KH-I_PNO1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000009">
        <property type="entry name" value="RNA-binding protein PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055212">
        <property type="entry name" value="KH-I_PNO1_first"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055211">
        <property type="entry name" value="KH_PNO1_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826">
        <property type="entry name" value="RIBONUCLEASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF13">
        <property type="entry name" value="RNA-BINDING PROTEIN PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22891">
        <property type="entry name" value="KH_PNO1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="10">
        <location>
            <begin position="164"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00071744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="259" mass="28630" checksum="D8D1B2B160F8CCC6" modified="2014-04-16" version="1">MPAPTALQRRPEELADNVALEASSVSLPTESDGDLISMSIDPVDAPNTTSDAPEEDMPMVDESGKPKFPAAKSIPLAFRREQRKVPIPPHRMTPLKNSWPKIYPPLVEHLKLQVRMNTKSKSVELRTSSATTDTGALQKGEDFVKAFTLGFDTDDAIALLRLDDLYIETFEIKDVKSLSGEHLSRAIGRIAGKDGKTKFAIENASRTRIVLADQKIHILGGFKNIHIARESIVSLILGQNPSKMYGNLRTIAGRMKERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTR3</accession>
    <name>W6YTR3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_40839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964131">
        <property type="protein sequence ID" value="EUC40923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692568.1">
        <property type="nucleotide sequence ID" value="XM_007694378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTR3"/>
    <dbReference type="GeneID" id="19123950"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40839"/>
    <dbReference type="HOGENOM" id="CLU_2061091_0_0_1"/>
    <dbReference type="OrthoDB" id="10458099at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="119" mass="12749" checksum="D59367DD53FC8DB5" modified="2014-04-16" version="1">MEKQHEISIHVGGSATKERPVSARIRWATESSFRTASAVPNMEVAGLLACWLLDGAGGVASWYGALRLNCTHTRPVAMARVGVGQGWWRRRVSGLQRFAEGAATDPMQAKSDGLGGLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTU7</accession>
    <name>W6YTU7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_30184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964128">
        <property type="protein sequence ID" value="EUC40958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692511.1">
        <property type="nucleotide sequence ID" value="XM_007694321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTU7"/>
    <dbReference type="GeneID" id="19121633"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30184"/>
    <dbReference type="HOGENOM" id="CLU_2263274_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="103" mass="10888" checksum="92483E582FB1367F" modified="2014-04-16" version="1">MARSSQLAAPWAGAHSLDARAWSASQTLLHHIYTETLQPATSRPHPRPAIGSGLPILTRATGYGLRAAGCGQRRLVSIAATMSSLAPQSAFPLPAKTIIPHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUD9</accession>
    <name>W6YUD9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_106930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964117">
        <property type="protein sequence ID" value="EUC41148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692332.1">
        <property type="nucleotide sequence ID" value="XM_007694142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUD9"/>
    <dbReference type="GeneID" id="19118945"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106930"/>
    <dbReference type="HOGENOM" id="CLU_143611_0_0_1"/>
    <dbReference type="OrthoDB" id="10318609at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="112" mass="12826" checksum="3DD4D06937CC19F6" modified="2014-04-16" version="1" fragment="single">SLRYIVRGPCAGTNTHAIDMHHLTQLNATANTSTPKVEQRRVQWKWWWPGESARWQRFGSNQSIKVAGFERSFGNVSPRVCESVNLEAYKPPSLNKNPCYQGNYENHTIIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUU0</accession>
    <name>W6YUU0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_8931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964108">
        <property type="protein sequence ID" value="EUC41325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692135.1">
        <property type="nucleotide sequence ID" value="XM_007693945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUU0"/>
    <dbReference type="STRING" id="930090.W6YUU0"/>
    <dbReference type="GeneID" id="19127449"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8931"/>
    <dbReference type="eggNOG" id="ENOG502RY95">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008869_0_0_1"/>
    <dbReference type="OrthoDB" id="3248508at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF3">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="6">
        <location>
            <begin position="37"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="287"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="440"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="569"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="388"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="440"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="523"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="588"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="689" mass="78176" checksum="EDCAEEA9A038E9A5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVS4</accession>
    <name>W6YVS4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">proteasome endopeptidase complex</fullName>
            <ecNumber evidence="3">3.4.25.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_8683</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="3"/>
    <dbReference type="EMBL" id="KI964093">
        <property type="protein sequence ID" value="EUC41640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691842.1">
        <property type="nucleotide sequence ID" value="XM_007693652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVS4"/>
    <dbReference type="STRING" id="930090.W6YVS4"/>
    <dbReference type="GeneID" id="19126943"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8683"/>
    <dbReference type="eggNOG" id="KOG0173">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_3_0_1"/>
    <dbReference type="OrthoDB" id="429533at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03763">
        <property type="entry name" value="proteasome_beta_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000005">
        <property type="entry name" value="Proteasome subunit beta type-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024689">
        <property type="entry name" value="Proteasome_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF4">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12465">
        <property type="entry name" value="Pr_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0888">Threonine protease</keyword>
    <feature type="domain" description="Proteasome beta subunit C-terminal" evidence="12">
        <location>
            <begin position="221"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC41640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="276" mass="29825" checksum="E3E4257E40A4D075" modified="2014-04-16" version="1">MGGFDFSNHNRNVALHAQGIPLPKATSTGTTIVGCLFDGGVVIAADTRATSGPIVADKNCEKLHFIAPQIWCAGAGTAADTEFTTAIISSNLELHALSTGRKPRVVTCMTMLKQHLFRHQGHIGAYLVVAGVDPTGAHLFTVHAHGSTDKLPYVTMGSGSLAAMSVFETQWKAHLTRDEAVTLCSNAIEAGIWNDLGSGSNVDVAVITEEKTTLMRNYKTPNTRQPKQRNYRFQRGTTAVLNEKIIKKEEISKYVTVHELKDDDVTATAETMDVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWI5</accession>
    <name>W6YWI5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_41682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964228">
        <property type="protein sequence ID" value="EUC39889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693587.1">
        <property type="nucleotide sequence ID" value="XM_007695397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWI5"/>
    <dbReference type="STRING" id="930090.W6YWI5"/>
    <dbReference type="GeneID" id="19124112"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41682"/>
    <dbReference type="eggNOG" id="KOG4730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_530170_0_0_1"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016899">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886867" description="FAD-binding PCMH-type domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="32"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="487" mass="54677" checksum="7DEC6821AE4CF401" modified="2014-04-16" version="1">MPQAQYALLASSFLSVVFADPFNTFDGPGFPACREVAKVYDPKTVKETIDIVRTAAGNGTPIRASGKGHMWYDTMCSDNPSTVIVRIKQLNRISEFDLPVGTRDGSVMIEAGVTFFQLAEYLHLNNTSMGSIAMGAHRSSLREESMIAAGALELHIIDGNGELRVIKRSDSDEWLAASTSLGLLGVIAKVKFKIYPDFKVYSKQDIISEDKVLNGDIYGLIAPYGTANLWWWPYLCKFHHRYYDPIPAGLSDQEAFQSTFSVTKTEADFAAAGLLNSVKILPTSNMAAETLFFALWSPPNFRDKRTDKLIFNWPVYGWNYDVLIGGLYPGHGTQWDLGLRGLTLELAFPVTIANDVLKHVREAFDSELKKGIFGKPYNDLLGQVFTANEDGADWTKGAMMFDFPTFKPNWGDGKRFNEGFYDRLAKGLIERYPCRPHWTKDTRDIFNLTMVNKRIHSENLRRFKSVIEGFDPKGIFRSVIGEVLGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX88</accession>
    <name>W6YX88_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_99341</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 6"/>
    <dbReference type="EMBL" id="KI964014">
        <property type="protein sequence ID" value="EUC44012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689503.1">
        <property type="nucleotide sequence ID" value="XM_007691313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX88"/>
    <dbReference type="STRING" id="930090.W6YX88"/>
    <dbReference type="GeneID" id="19129450"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99341"/>
    <dbReference type="eggNOG" id="KOG0544">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_12_1_1"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF447">
        <property type="entry name" value="FK506-BINDING PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="20"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="124" mass="13353" checksum="A986D7CC6319D120" modified="2014-04-16" version="1">MGVEKIVAKPGNGTDFPKKHDEICVEYTGWLYDDEAPDNKGTQFDTSVGRGDLTTLIGAGRVIRGWDEGILGSEDIPPMSLGEVAILKITSDYAYGARGFPGHIPAGAKLIFEVELKSINKKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX92</accession>
    <name>W6YX92_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964013">
        <property type="protein sequence ID" value="EUC44017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689425.1">
        <property type="nucleotide sequence ID" value="XM_007691235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX92"/>
    <dbReference type="GeneID" id="19125008"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6579"/>
    <dbReference type="eggNOG" id="ENOG502TFC9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1304662_0_0_1"/>
    <dbReference type="OrthoDB" id="3231004at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="211" mass="23543" checksum="F7DD139959BD6C50" modified="2014-04-16" version="1">MRGAQSWWGASLAYYENAGIYTSALLDAYMDYKSIWKHIQVTNWEFESGITNLVKSTPTKELLDYAKECANEPPPAQKPATRDQTSTHTSGKRIEGSEHSQELQPKKNSFKPNILECEPYSASFVGLNKARRDCRLEMTKIVNEVDAVTKDPSIALQPDRVGIYLAPSIFRQLLPIKQAVQKEPTPAPNPDPNPDPSPNPTPDPNPNPNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY18</accession>
    <name>W6YY18_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC-type Fe3+ transport system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964164">
        <property type="protein sequence ID" value="EUC40449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693023.1">
        <property type="nucleotide sequence ID" value="XM_007694833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY18"/>
    <dbReference type="STRING" id="930090.W6YY18"/>
    <dbReference type="GeneID" id="19119310"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108789"/>
    <dbReference type="eggNOG" id="ENOG502SM1W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_5_0_1"/>
    <dbReference type="OrthoDB" id="124329at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30006:SF2">
        <property type="entry name" value="ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30006">
        <property type="entry name" value="THIAMINE-BINDING PERIPLASMIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13343">
        <property type="entry name" value="SBP_bac_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="35728" checksum="63F168290C11F1EE" modified="2014-04-16" version="1">MWLGGDERTDEDALKNEFEKRFPGMKLNLTTDLSKYHSPRFDEQLAAGKVYVDSIAFQTVHDFPRWDNEGALLHYAPVGLDKVYVPMKDVRAAFYGILTVGWAGKWNSDKLPGIQAPVEWEDWLRPEFKDKLVLTYPNDDDAVLYAFDLIMQQYGKSWFQKLLKQNPRWIRGTRSPDTIMQAKNSTRAASFTSDGLFPTSNIKISHPVKGSFVTWFQLAAIPKDAPHPEGAKLLHNYMLTKEWQATRGSWPVRSDVEPPQGYPSILEMPGTNITYFREWMSDRYRVERLRLWFEDQLGTAQGLSPISDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY23</accession>
    <name>W6YY23_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_46643</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964163">
        <property type="protein sequence ID" value="EUC40459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693008.1">
        <property type="nucleotide sequence ID" value="XM_007694818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY23"/>
    <dbReference type="GeneID" id="19124326"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_46643"/>
    <dbReference type="eggNOG" id="ENOG502SYJ3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018141_0_0_1"/>
    <dbReference type="OrthoDB" id="5600002at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058251">
        <property type="entry name" value="zf_Tbcl_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058252">
        <property type="entry name" value="zf_Tbcl_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26647">
        <property type="entry name" value="zf_Tbcl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26648">
        <property type="entry name" value="zf_Tbcl_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Probable treble clef zinc finger" evidence="2">
        <location>
            <begin position="16"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Probable treble clef zinc finger fungi" evidence="3">
        <location>
            <begin position="61"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="64195" checksum="091E20F80B7347C9" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYR6</accession>
    <name>W6YYR6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964147">
        <property type="protein sequence ID" value="EUC40664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692806.1">
        <property type="nucleotide sequence ID" value="XM_007694616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYR6"/>
    <dbReference type="GeneID" id="19128520"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9482"/>
    <dbReference type="HOGENOM" id="CLU_558945_0_0_1"/>
    <dbReference type="OrthoDB" id="3674902at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="488" mass="54708" checksum="D3B2DA35B17D31E4" modified="2014-04-16" version="1">MSESLEARGQPWSRTKSNRDPSDEMADAATTLLMICGGHTQLPTAPTIEKQDVLFCSPEGHLLSSTAEKEGARLSPGRIDKHQGAVHANARAAIPCSIHHVTDSAVDISTGQELHDADFMEAFTHWNEATWALEQETALSEATGNNHLDEDLVLASDPSRHQNIDELFYATEVAEMHQTGYFSNIDPKETLLGYQERAVVPHDATDVLGEMRSSPLLQNHRSPSNHDTLEVVPNDTERAEWSNDSVSITTHTKNIEVLVLDNSSKSNDSSDEMEGTAGDQSIWSGSQHAARSHTPLITDTNNGEVIIIDDSSNSDDSSDEMEDITKDRRTWPGSQRRARSRHQRVLHGMVQWSDARLERRNYTAIQQLWINAQKYWKSMQALKCFAKSKRVKKFDKMMIRAKKHVQKNGGTILLYDVGKLHRKFRHILPGLRMRLESSNQKKFLDNVDATLKELYTVVEVTMLMTEQPANDDDENDGDYRPGGATGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYV3</accession>
    <name>W6YYV3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_102710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964050">
        <property type="protein sequence ID" value="EUC42758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690734.1">
        <property type="nucleotide sequence ID" value="XM_007692544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYV3"/>
    <dbReference type="GeneID" id="19118141"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102710"/>
    <dbReference type="eggNOG" id="ENOG502RGCP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096588_0_0_1"/>
    <dbReference type="OrthoDB" id="3438340at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021641">
        <property type="entry name" value="DUF3245"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11595">
        <property type="entry name" value="DUF3245"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="241" mass="26802" checksum="A858A64BE2B04215" modified="2014-04-16" version="1">MSKRNNEGDVIANRISLLEAKGQKLLASLYGSRPDWDTRDNAATPQDEDDQDLKQNYAYDRIGLGGILPKDVENGSFTKRTLTSDDKLLQQLIGKKKAKAHIMAKQEAARPSAATKTHQYSKPAVAKKEVSDDEEDGRAATFKSKRGDRKAKKPPILPDSDDEDEEMRAKRLAAGMKAENQETKEPTTEAPVEDKSSEKVKEEEEAEPAQPAPKKVKIKPKSFLDEILAERSKKKSKKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ12</accession>
    <name>W6YZ12_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964140">
        <property type="protein sequence ID" value="EUC40774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692701.1">
        <property type="nucleotide sequence ID" value="XM_007694511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ12"/>
    <dbReference type="GeneID" id="19123972"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40945"/>
    <dbReference type="eggNOG" id="ENOG502SKEA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024756_0_0_1"/>
    <dbReference type="OrthoDB" id="446809at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF1">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="499" mass="56801" checksum="878E4D2CEA656611" modified="2014-04-16" version="1">MGPPRTRSFRFMLVGIGPHAKRTYVKHFRSLKAEGRGEIVAAVDIISQRSSLEPYAAEHLPDTQLIFVPQFRGRMPPTVTEALTRVARSLGVDCIIVSTEPECHKPYGLWAVSLGLHVIMDKPISTRRQASNDPEEAAGIADDYNELLEAYTELQKHKETMFLINSHRRYHPGFLGTRDFITDIRNKTNCPVTSLISTHCDGQWRLPDEIVDQHYHPFRYGYGKISHSGYHFLDTCYKFFEAGWSAGKRPDQIEMVTTFSRPNDFMYSLSHEEHGQALGRDEYNKHAKYSADELREHMQSMGEVDAMIQITFRSRGNVLGMAQLNLLHTGFSRRDWIDQGANPDLYKGCGRVKHEAHEVRSGPFQTIVIDSRQANDKHDRSKPSTAELGSDNHFEVQTWRNCGVLGEDEPLKTYTIDDLDKRFNTKATGIYMENIKQGILWEALNFLEGSIPIDALTSNLPDHSIPATMMSAAYMSHIRRSRGLNPITHINITYTNEDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZN4</accession>
    <name>W6YZN4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen debranching enzyme</fullName>
            <ecNumber evidence="5">2.4.1.25</ecNumber>
            <ecNumber evidence="6">3.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Glycogen debrancher</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_7427</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of (1-&gt;6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.</text>
            <dbReference type="EC" id="3.2.1.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the glycogen debranching enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="5"/>
    <dbReference type="EC" id="3.2.1.33" evidence="6"/>
    <dbReference type="EMBL" id="KI964040">
        <property type="protein sequence ID" value="EUC43075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690382.1">
        <property type="nucleotide sequence ID" value="XM_007692192.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6YZN4"/>
    <dbReference type="GeneID" id="19125284"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7427"/>
    <dbReference type="eggNOG" id="KOG3625">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001517_2_0_1"/>
    <dbReference type="OrthoDB" id="10248904at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004135">
        <property type="term" value="F:amylo-alpha-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11327">
        <property type="entry name" value="AmyAc_Glg_debranch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000039">
        <property type="entry name" value="Glycogen debranching enzyme Gdb1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000242">
        <property type="entry name" value="Glycogen debranching enzyme Gdb1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000333">
        <property type="entry name" value="Glycogen debranching enzyme Gdb1, putative (AFU_orthologue AFUA_1G02140)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010401">
        <property type="entry name" value="AGL/Gdb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032788">
        <property type="entry name" value="AGL_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029436">
        <property type="entry name" value="AGL_euk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032792">
        <property type="entry name" value="AGL_glucanoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006421">
        <property type="entry name" value="Glycogen_debranch_met"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01531">
        <property type="entry name" value="glyc_debranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569:SF2">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14701">
        <property type="entry name" value="hDGE_amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14702">
        <property type="entry name" value="hGDE_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14699">
        <property type="entry name" value="hGDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Eukaryotic glycogen debranching enzyme N-terminal" evidence="18">
        <location>
            <begin position="48"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme glucanotransferase" evidence="19">
        <location>
            <begin position="146"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme central" evidence="20">
        <location>
            <begin position="752"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme C-terminal" evidence="17">
        <location>
            <begin position="1086"/>
            <end position="1540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF14699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF14702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC43075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1559" mass="176524" checksum="F28347FCDE9394C1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZT5</accession>
    <name>W6YZT5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964040">
        <property type="protein sequence ID" value="EUC43098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690389.1">
        <property type="nucleotide sequence ID" value="XM_007692199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZT5"/>
    <dbReference type="GeneID" id="19121302"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28410"/>
    <dbReference type="HOGENOM" id="CLU_1180043_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="235" mass="25306" checksum="C029996EC3A3DA11" modified="2014-04-16" version="1">MACTHTVGCLSSCAQPQGVLAAGSWKLPAAGQPCAQVYMRLSSIHSASLSGRANCGARRTYYLDFSASSCLGVAAAGSLLPLPAMCQTAVAANGRAEQHPHHEPVTVRPCGQPSRHSLVCSAATMDWRSVKATRRISVEKWAWGKEPCRPQLVQMQALSQACFSLRTAPSREKKKKKSSTSDSRAEEPTGNGFVQRRSQFGQLGGSRGDDRRRAAKTSEQRIESRLEGDQACDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0J7</accession>
    <name>W6Z0J7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_100620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964027">
        <property type="protein sequence ID" value="EUC43485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689982.1">
        <property type="nucleotide sequence ID" value="XM_007691792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0J7"/>
    <dbReference type="STRING" id="930090.W6Z0J7"/>
    <dbReference type="GeneID" id="19117714"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100620"/>
    <dbReference type="eggNOG" id="KOG1529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031618_3_1_1"/>
    <dbReference type="OrthoDB" id="270167at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01448">
        <property type="entry name" value="TST_Repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01449">
        <property type="entry name" value="TST_Repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000001">
        <property type="entry name" value="Sulfurtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000033">
        <property type="entry name" value="Thiosulfate sulfurtransferase TUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364:SF27">
        <property type="entry name" value="SULFURTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="THIOSULFATE SULFERTANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="89"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="217"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="340" mass="38040" checksum="E4CD1615F947E1A8" modified="2014-04-16" version="1">MFVSRFHCSLRSPSCFVSSLRYLVSVANRRAMSSHEKLRSYLVTPAELNSALKLNASKLSHEPRIIPLCASWFLPNDDRNGYETFLAQHIPHSQFFDLDAVKDVHSPYPHMLPSPSEFADAVRHLGIRREDSVVVYDSKELGIFSAPRVGWTFQVFGHPRVHVLNNFRKWVEEGYPTESGEPKAPEITEYEVPQLDEKKVIAFEQVKEIAKELGKEGADEVQILDARSLGRWKGVDPEPREGLSSGHIPFSISVPVADLLDPNDKTLLPASKLKAVFESKGIKPDVPIISSCGTGVTAAIIDAALTEAGYPTQQRRLYDGSWTEWAQRVKPTEGLIHKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1N5</accession>
    <name>W6Z1N5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_8756</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964097">
        <property type="protein sequence ID" value="EUC41559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691923.1">
        <property type="nucleotide sequence ID" value="XM_007693733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1N5"/>
    <dbReference type="GeneID" id="19127092"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8756"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_2_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF315">
        <property type="entry name" value="TRANSPORTER MCH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="333"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="46849" checksum="A1B910A35B0123DC" modified="2014-04-16" version="1">MGVEYTSSRHQSPRLSPGDADDAGIENVQSEDLVPPDGGYGWVCVAACFTINCFTWGAVSAYGIYLSHYLAEDLFPEATTWDYAFIGGFNFAIAMVVAPAVTVLCRKFGIHVVMCCGLLFQLAGFISASFSHRIWQLHISQGVLIGCGIGFLYIPCLPVLSQWFEKRRSLANGISAAGSGVGGAAFAWGSEAIIQRFGIAWALRITGILAFTANTTAIIFIRDRNKAIRPSQLGFDTRLLRRGDVLLLLAWAFISMLGYIVLLFSLSDFALSIGLSRSQATDMIGLLNMGTAIGRPIIGILSDRWSRIDTAGALTLLCGLACFAFWLPSTSYGLTVFFVILCGAIVGVFWMTIGPLCVEVAGIKDLQSLLSLSWAAVIIPSIVSEGIALKLRRPSSSREYLYVQVFAGLAYIVASALMLQLRRVKRRQARSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z223</accession>
    <name>W6Z223_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_5038</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687656.1">
        <property type="nucleotide sequence ID" value="XM_007689466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z223"/>
    <dbReference type="STRING" id="930090.W6Z223"/>
    <dbReference type="GeneID" id="19124477"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5038"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016304_6_2_1"/>
    <dbReference type="OrthoDB" id="446113at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
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        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
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        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF10">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="64"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
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            <begin position="161"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="293"/>
            <end position="365"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
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        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
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        <location>
            <begin position="362"/>
            <end position="469"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
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            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
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            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
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        <location>
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            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="458"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="469" mass="49598" checksum="EA3DCD2E4A8E8A2F" modified="2014-04-16" version="1">MSFNNGYNDQFQGPPQGDMNNPTPQPGDMGQPMDTSGNGFPPQGNMGPPGSAGGDGQGQGAGKTTLWMGELEPWIDENFVRSIWYNMGETVNVKMIRDKFSGSNAGYCFVDFASPDAAAKALNLNGQLIPNSNRPFKLNWASGGGLADRRQVIRDERGPEFSIFVGDLGPEVTEFVLVQLFQNKYPSTKSAKIMSDPISGMSRGYGFVRFASEEDQQKALTEMQGVYCGNRPMRISTATPKNKSGGPGGPGGMGMPQGAGGPGMGMYSMGAPPMGNYYGAPQPMNQFTDPNNTTVFVGGLSGYVTEDELRSFFQGFGEITYVKIPPGKGCGFVQFVQRHAAEMAINQMQGYPIGNSRVRLSWGRSQNNSGPAGTPYRPAPPPPVPFGPGMGMPPQHPYGGGGGGYGPMMKASLPPPYSSIANNNYAGSQNDSQNAPTLQSGAANGLQSGLGGFARFTPPQSNDTNGSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2B9</accession>
    <name>W6Z2B9_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_99688</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502S522">
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    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF1">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
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        <location>
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            <end position="102"/>
        </location>
    </feature>
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        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="8"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC43853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="168" mass="18389" checksum="237E4F0574E33519" modified="2014-04-16" version="1">MAMNWMLPVRAAQAVLSIVVLGLMAYVSSWWSSHWRQSSPIEINYLIFAPAWSLLTLAPLILISLGKFTHLAEQTAMKWALLGIEGMTMLFWLSGFVSLGVFLNGRICFGMVCDVARASTAISAISWFAWMATFGLGVMAVIKGRKAGASSVGKKPYGNEEIKMHQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2F8</accession>
    <name>W6Z2F8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_94091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2F8"/>
    <dbReference type="GeneID" id="19128389"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94091"/>
    <dbReference type="HOGENOM" id="CLU_1255785_0_0_1"/>
    <dbReference type="OrthoDB" id="10583366at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="220" mass="23468" checksum="5616C59CF85A2EA0" modified="2014-04-16" version="1">MPWARTSRRNSTTTRHDSHYMRTAPPPSNASAAPRGTSARAPSVSSRHGNYAQPSSNHGRTASNHPGTSAHQSSHHGRTAPPPSRYAASVQATNPPHTHTWQSRSYAGSVASRAYSQRPPFSQGARTAASMQRQLTVPNQTRGQGGASAAGSRSRAPTAVQTRGADRGRSVVPASDVGGVGGQGGQEVVGYAYETVQVGGRRGSRWSRFRMFVWRRGSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2H6</accession>
    <name>W6Z2H6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_8509</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KI964084">
        <property type="protein sequence ID" value="EUC41839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691640.1">
        <property type="nucleotide sequence ID" value="XM_007693450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2H6"/>
    <dbReference type="ESTHER" id="cocca-w6yar2">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="19126597"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8509"/>
    <dbReference type="eggNOG" id="KOG4389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_5_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000499">
        <property type="entry name" value="Carboxylic ester hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005151137" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="40"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="550" mass="58813" checksum="A191EAB95459B7A6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z356</accession>
    <name>W6Z356_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_49237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964010">
        <property type="protein sequence ID" value="EUC44158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689328.1">
        <property type="nucleotide sequence ID" value="XM_007691138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z356"/>
    <dbReference type="STRING" id="930090.W6Z356"/>
    <dbReference type="GeneID" id="19124430"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_49237"/>
    <dbReference type="HOGENOM" id="CLU_2190109_0_0_1"/>
    <dbReference type="OrthoDB" id="16547at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="110" mass="12908" checksum="C2088BED267C2042" modified="2014-04-16" version="1" fragment="single">EEDVPLFNLDLLNIKPADRQWFMDVNIAVRELANSPDNPKDYSYIRRVVSNAAHILNDEVKHYEWARKLDPLIIWVSCMVHTVSRQLYRAAEKSCDPLDVIDEFLKSYIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z437</accession>
    <name>W6Z437_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">INSIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_6007</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the INSIG family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688769.1">
        <property type="nucleotide sequence ID" value="XM_007690579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z437"/>
    <dbReference type="STRING" id="930090.W6Z437"/>
    <dbReference type="GeneID" id="19124801"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6007"/>
    <dbReference type="eggNOG" id="KOG4363">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039316_1_0_1"/>
    <dbReference type="OrthoDB" id="205546at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025929">
        <property type="entry name" value="INSIG_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301">
        <property type="entry name" value="INSULIN-INDUCED GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301:SF3">
        <property type="entry name" value="PROTEIN NSG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07281">
        <property type="entry name" value="INSIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="99"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="46158" checksum="473450FF1A529E8C" modified="2014-04-16" version="1">MGGDPSNVHAAPPPLHIHRPIPRRTFERSDSADSPTHDFTQSTPPSATENRRANDFVAQLNARLLRTYYSSRHDDSDEQERSLPPRNQSLLNLTSSTLSGIYDESGDQSSIETPWGTGAETPKHTFAGSQTRATGVGSPDGGVSLYNRARSGSAMYPPDARKRSHSIKQPRQGTWKYLVITGKLAALYIFGVLYGVIVSHIHETKQLAAIHVDGVDQKGHAYLATWGLFGVALGSLLPYVDLLWDSQSTESEIQPGGKEVEEHDPPISEQVNDIVRSVAAFIGIAFAIRRLPWQSTLQLTLTLALVNPALWYILDRSKPGLSVSLTVTSILTSLIFLSNPDVLPSPFLPASVNATHLPSTTQNSQVKGGLNTGAPMAQTTFFGMITYEELAVVTWVGSVLFCSCVCFGSIGRRLAVLDETPRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z513</accession>
    <name>W6Z513_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HORMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_37376</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963996">
        <property type="protein sequence ID" value="EUC44848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688635.1">
        <property type="nucleotide sequence ID" value="XM_007690445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z513"/>
    <dbReference type="STRING" id="930090.W6Z513"/>
    <dbReference type="GeneID" id="19123236"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37376"/>
    <dbReference type="eggNOG" id="KOG3285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072097_0_0_1"/>
    <dbReference type="OrthoDB" id="1806at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033597">
        <property type="term" value="C:mitotic checkpoint complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990498">
        <property type="term" value="C:mitotic spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905318">
        <property type="term" value="P:meiosis I spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.900.10:FF:000002">
        <property type="entry name" value="Mitotic spindle assembly checkpoint protein MAD2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF11">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="8">
        <location>
            <begin position="38"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="244" mass="27056" checksum="265B102C4B03698C" modified="2014-04-16" version="1">MSAPKATAKTSSKSSSKTSSKSKSSKSDSSKVHKLALKGSSKIVNEFFEYCINTILFQRGVYPAEDFTAVKKYGLTMMVTADDQVKAYIKKIMGQLKEWMYGGKISKLVIVITSKETGEHVERWQFDVQIFGKGSKSKTSKKDTDQENAAPEASDAPEEKTEAEIQAEIQSIFRQITASVTFLPMLDGNCTFNVLVYADADSDVPLEWGDSDAKEIQNGEKVQLRSFSTSNHRVDTLVSYRLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z516</accession>
    <name>W6Z516_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688387.1">
        <property type="nucleotide sequence ID" value="XM_007690197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z516"/>
    <dbReference type="STRING" id="930090.W6Z516"/>
    <dbReference type="GeneID" id="19123189"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37129"/>
    <dbReference type="eggNOG" id="KOG3035">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051989_0_0_1"/>
    <dbReference type="OrthoDB" id="671439at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01838">
        <property type="entry name" value="Isoamyl_acetate_hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045136">
        <property type="entry name" value="Iah1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209:SF19">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="266" mass="29790" checksum="3AB637F1744D7E12" modified="2014-04-16" version="1">MSAPYEQFFLLGDSITQESFSQERGFAFGAALQAAYIRRLDVVNRGFSGYNSRQALQILPAIVPPPSQAKIRLMTVFFGANDASLPDAPNKQHIPLDEFKANLRAIVSHPCIVAHAPRIILVAPPPMNEHLWWPRDQSSGYATVSRLAETTKIYADAVVQLGAELHLPVLDLWKAFMSRTDFHVDTWKLGDHVPGSLALPPSAALADLMYDGLHMNPPGYQILYDELINVISRNWPDQLPDKLPMVLPPWNDEVAWKAWRSHHVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5N3</accession>
    <name>W6Z5N3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_96474</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688401.1">
        <property type="nucleotide sequence ID" value="XM_007690211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5N3"/>
    <dbReference type="STRING" id="930090.W6Z5N3"/>
    <dbReference type="GeneID" id="19128861"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96474"/>
    <dbReference type="eggNOG" id="KOG0239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001485_12_1_1"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01366">
        <property type="entry name" value="KISc_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000065">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF45">
        <property type="entry name" value="PROTEIN CLARET SEGREGATIONAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 10 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="472"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="104"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="486"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="206"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="361"/>
            <end position="472"/>
        </location>
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        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="563"/>
            <end position="570"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45088.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="818" mass="92739" checksum="96DA71A00F906D22" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6Z658</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
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    </dbReference>
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        <source>
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            <dbReference type="EMBL" id="EUC43044.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
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</entry>
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    <name>W6Z6C6_COCMI</name>
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        </recommendedName>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689742.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19123103"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36737"/>
    <dbReference type="eggNOG" id="ENOG502SKZZ">
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    </dbReference>
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    <dbReference type="OrthoDB" id="3902588at2759"/>
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    </dbReference>
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        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
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        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
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        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
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        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
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        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
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        <location>
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            <end position="122"/>
        </location>
    </feature>
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        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
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        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45550.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="66901" checksum="9F9AECCDDF7C1D04" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6L4</accession>
    <name>W6Z6L4_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_95543</name>
    </gene>
    <organism evidence="4 5">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963984">
        <property type="protein sequence ID" value="EUC45458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688060.1">
        <property type="nucleotide sequence ID" value="XM_007689870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6L4"/>
    <dbReference type="STRING" id="930090.W6Z6L4"/>
    <dbReference type="GeneID" id="19128682"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95543"/>
    <dbReference type="eggNOG" id="KOG0907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_14_5_1"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000245">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="13"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="158" mass="17395" checksum="ECD22EA3F2517064" modified="2014-04-16" version="1">MFAPSSFRATRTLLTSVRLQTASINPTSTTNLYRPLFTPRFFSNTAKMSEQKEGVHNLSSKADFDAALNDKETLLVLDCFATWCGPCKVIAPQVVKFSKEYPTARFYKLDVDDVPDVAQELGIRAMPTFLLFKGGDKVAEVVGANPKALEAAIKANLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z757</accession>
    <name>W6Z757_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Complex I-B15</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_94909</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z757"/>
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    <dbReference type="eggNOG" id="ENOG502S8RT">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183941_2_0_1"/>
    <dbReference type="OrthoDB" id="15108at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39476">
        <property type="entry name" value="NADH:UBIQUINONE OXIDOREDUCTASE 6.6KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9576" checksum="9C19D7767D223DE4" modified="2014-04-16" version="1">MQPTLRRMAGHNHGMIHADPAIIKWATMTTNRHKYFRWTRRTAWITFAYVALVPGLLGAAGYWAEGRWEMRGKRRGDTISEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7Q6</accession>
    <name>W6Z7Q6_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36250</name>
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    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC46045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689212.1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_36250"/>
    <dbReference type="eggNOG" id="ENOG502QTM1">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_450523_0_0_1"/>
    <dbReference type="OrthoDB" id="5396at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
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        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF10">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="606" mass="67005" checksum="9F01F66E1DDA75F0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7U7</accession>
    <name>W6Z7U7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_26014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7U7"/>
    <dbReference type="STRING" id="930090.W6Z7U7"/>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="119"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="508" mass="57205" checksum="1CC2C4E04209D80E" modified="2014-04-16" version="1">MSTSPSLRSSSFGDRPRPSTPDSIPSAASRGSYFSVAPKSEYLKNAIHARRAQPSPSLPPQDLIPKPSSPAPSSPQQTTARVSPDIFLQYALSEEQTAPVSPVQRKRPSDFGYATSKTNRELSKEIERLKESLMTANLRVELLSRNKKESQDKLASALETIERLESIEDEVHDLRAENKKLKLRVNSMKEEMARLNKVNEDHRKINEELTTIASESAAHWSAHESAIDEAAECIIKMEEEKAALSQELQELKERVAAIERVSSETPLALGLDKYPSRVYSVDESRPSTSHFDSDYYSQPDSPQPKPSSESVNSLRPSERSRKFLDSTEQHRRSARSLVQRMSAASLRALSEATPCPTYQQQIATVEEEDRSPTPRKASVQRRRGHDAASPTLMPAAEICSSRPHTVTPYAETTPHPDGLRALYHPDRARNRRANNLRSSSGQFDSPTNLHRLATRPQTTYETWQRPGFAESEVDLTSVVDPLEDKERWWRSMDRLNIDHVIARYTTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z825</accession>
    <name>W6Z825_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_4777</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964014">
        <property type="protein sequence ID" value="EUC43999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689487.1">
        <property type="nucleotide sequence ID" value="XM_007691297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8Y0"/>
    <dbReference type="GeneID" id="19123402"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38122"/>
    <dbReference type="HOGENOM" id="CLU_2359403_0_0_1"/>
    <dbReference type="OrthoDB" id="3683789at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068023" description="Secreted protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="12400" checksum="817305D057AFCAE9" modified="2014-04-16" version="1">MRLFITIWYASVVCRLFSILTKDYLLGTVTSPQVPLIIHTCAMHDRSSGLYTMSRYRHTVATAPIHKSNRGEKKRSSFSESVDWYLRREIQGKGKNIWKTMLEYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z906</accession>
    <name>W6Z906_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_92677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686999.1">
        <property type="nucleotide sequence ID" value="XM_007688809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z906"/>
    <dbReference type="GeneID" id="19128118"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92677"/>
    <dbReference type="HOGENOM" id="CLU_3013859_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="56" mass="6352" checksum="E20B5159BA6003B1" modified="2014-04-16" version="1">MRVGDVQVGNTNCGFARQAAKSCATWRSHVDRMRGDYEYYPKPKRQFGLHGSGIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z950</accession>
    <name>W6Z950_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_92480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686906.1">
        <property type="nucleotide sequence ID" value="XM_007688716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z950"/>
    <dbReference type="GeneID" id="19128086"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92480"/>
    <dbReference type="eggNOG" id="ENOG502S247">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_652123_0_0_1"/>
    <dbReference type="OrthoDB" id="2142040at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34706">
        <property type="entry name" value="SLR1338 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34706:SF1">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="348"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="40519" checksum="AD99CC0BE43A89A3" modified="2014-04-16" version="1" fragment="single">RILSEKGGDDSMSYKPVTPRASPVLRAPSCNFKVELEVEETLQLGSQKPHRESLGSSETDPYAFLKPFDTIFLIDDSGSMAGRSWQETRKALESVTPICTHYDGDGIDLYFLNHTDSTKPINTIDKTDGKPTDDADAPIIAAAKKLGNIEAPKWQAGIQFSKVGKEEGVYAVFEQLDDRLTELSGDEKILMPYLQKVLSAWCRAFHNTAPKDFDSFRIKSRIQFLHINPAALTFLAVFAQLPIIQAANRHISTTWGIPISNTLGVGTGLAISVFDDEANTNPVLYWIVYGFSSLSALLVVTFTTFSIKKSSRLRYLCTFVLVEFILLTVIAVSSISDDGFVTKHLKEWTPLATVAIAGALTAGFKRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9G2</accession>
    <name>W6Z9G2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mRNA export factor GLE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleoporin GLE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_92741</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687049.1">
        <property type="nucleotide sequence ID" value="XM_007688859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9G2"/>
    <dbReference type="STRING" id="930090.W6Z9G2"/>
    <dbReference type="GeneID" id="19128133"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92741"/>
    <dbReference type="eggNOG" id="KOG2412">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018821_0_0_1"/>
    <dbReference type="OrthoDB" id="420884at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012476">
        <property type="entry name" value="GLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960">
        <property type="entry name" value="GLE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960:SF0">
        <property type="entry name" value="MRNA EXPORT FACTOR GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07817">
        <property type="entry name" value="GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="143"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="143"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="202"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00026227"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="562" mass="63421" checksum="FCF6EC73FF07D877" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6Z9J5</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="246" mass="28750" checksum="ECC7863B6C27A0C1" modified="2014-04-16" version="1">MTSDAQNNPFIRNLASSDKKVRDQALDALKQYLGAQSEISELDLLKLWKGLFYCLWMQDKPTLQQRLSRDLASLVSTLRTPVVLPFIRAFFLTMSREWGHIEALRLDKYLYLIRQYVNASFAFLSRNKWKKSLLKQWNSIMEEMPLECKNMRIPNGLRYHVMDVWVDELENVEGDEWEKDENKETLETLVEPIESMAKNGNLKPLRNAAKECLADERLRAWRGQEAEVASEPEEEDEEAEWGGFAD</sequence>
</entry>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="PANTHER" id="PTHR36156:SF3">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="90"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="186" mass="20603" checksum="21CCCFE1F09476D0" modified="2014-04-16" version="1">MAPQTDVPNDLPKINRFITTHDPATKQAVFFNDIPDEHKVDPIPGADFRLGYVTKGFPVDLNNDADLKVYKPYLESSPGLVVSGGTVLRFVDVAPGHLSPMHRTVSLDYGVVLEGEFELVLDSGETRHMKRGDVAIQRGTMHAWRNLSSTSWGRMMYVLQECKPVEISGEALKEDYGTMQGVPKSS</sequence>
</entry>
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    <accession>W6ZAF1</accession>
    <name>W6ZAF1_COCMI</name>
    <protein>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_86570</name>
    </gene>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="144" mass="15604" checksum="BAC94F7F381379B4" modified="2014-04-16" version="1">MAVSFLAVFAGLIALTATYLYVFGISPELKRKMERQALKTMGENKMSYMTKDAIDKVPASDQENIKSLKKGLGNIAGGATQNPLGEQTVHAVTQARDSASNSTKNVWLDWDTVQSYPKAALDRVSAMTNKAQDTAQSYVPEKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAM4</accession>
    <name>W6ZAM4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_35464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC47030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686484.1">
        <property type="nucleotide sequence ID" value="XM_007688294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAM4"/>
    <dbReference type="GeneID" id="19122787"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35464"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_4_1"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC47030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="57164" checksum="27F5A9E59F8ADEDF" modified="2014-04-16" version="1">MSLLSHAHAPDSAVLLSAALAALAAYVVAALTYNIYLHPLASFPGPPLAGATVYWKAYIECIANRSFCHYLVDLHARYGDVVRVGPNELHFANPQAYHDIYNNKNRWDKEARLYKSFNEDRSSFGFLTYAEAKDRKHVLNPSFSQAAIRSAESLCVDKIKALCAAFERQARASKPTDLFYAFRCMSVDVITTLCFGNPIHAVDAPDFNAPIVVALDASTPVALYFKYSDLFKNFILKCPPKISRILSPLMAGLIDLNQLLMQQINDLTNDPEKLKLLPHNMTIFHRLMDPEAHRDKKVPSAGSLYEETQALMFGGADTTGNTLMVGSFHLLKDPARLQKFKTELLEHWPSLQDSEPKLKDMEDLPYLNAVIKESLRLSSGVTAGLLRVVPATGATITGRVVPPGAIVSCGSTFVHYNAEIFPEPDKFVPERWLETPELDNWLVAFSRGPRMCLGINLAWAELRLTFAHVFRKFDMTVPKQLPETLLWRDVFLPYYYSEHLQVNMRPIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAY5</accession>
    <name>W6ZAY5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein O-GlcNAc transferase</fullName>
            <ecNumber evidence="3">2.4.1.255</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_97674</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.255" evidence="3"/>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688845.1">
        <property type="nucleotide sequence ID" value="XM_007690655.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZAY5"/>
    <dbReference type="GeneID" id="19129106"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97674"/>
    <dbReference type="eggNOG" id="KOG4626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001721_0_0_1"/>
    <dbReference type="OrthoDB" id="421121at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000552">
        <property type="entry name" value="UDP-N-acetylglucosaminyltransferase (AFU_orthologue AFUA_1G03380)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11380:FF:000004">
        <property type="entry name" value="UDP-N-acetylglucosaminyltransferase (AFU_orthologue AFUA_1G03380)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000110">
        <property type="entry name" value="UDP-N-acetylglucosaminyltransferase protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 8" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="565"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="925"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="10">
        <location>
            <begin position="1161"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="10">
        <location>
            <begin position="1420"/>
            <end position="1621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="378"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="379"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="646"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1644" mass="182713" checksum="73C6F78E22366651" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBB8</accession>
    <name>W6ZBB8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_85729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684464.1">
        <property type="nucleotide sequence ID" value="XM_007686274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBB8"/>
    <dbReference type="GeneID" id="19126722"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85729"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="53" mass="5978" checksum="EE39C747B5431325" modified="2014-04-16" version="1">MFCMHFDLEAEAAYIDHSTWFIHRPYTVTCTESGITSVHIAGRSNNVTWSSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBE8</accession>
    <name>W6ZBE8_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">DUF3176 domain containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_85364</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="707"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="811" mass="90323" checksum="0467CF12433FA686" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC07</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_26740</name>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886693" evidence="2">
        <location>
            <begin position="21"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="190" mass="19387" checksum="8A90A56BFFFD42C8" modified="2014-04-16" version="1">MLFNKKTLALAALFSTLASGRPFDSAGAGKLAARSKSYAVVNVGGDSTETSATPTSTIKTTTTVEVVVPGETVTREVTATVVKPNPAPAPTPCPSSSSVTASSSSSLSVSSTSTPISSTPPISTPTTPTSVPSNSTSMPIETPKPIFITVTVSEDDGPTEYYDNGMWHTNYRIKTFEGDVAAAPTAPPAA</sequence>
</entry>
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    <accession>W6ZCB4</accession>
    <name>W6ZCB4_COCMI</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_96438</name>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690202.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19128852"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96438"/>
    <dbReference type="eggNOG" id="ENOG502R2G0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165609_0_0_1"/>
    <dbReference type="OrthoDB" id="3783571at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="95" mass="10694" checksum="DF661166C6A89B0C" modified="2014-04-16" version="1">MSTSTTTTPRTSTDKLNSWKSLSSAISVRSSACASTLKEPSKTRSLWNSIKRHTQEHHQSLNAAYATYYGQGSYLDEHCGARNQEHWRYRRGGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCU7</accession>
    <name>W6ZCU7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_89500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685879.1">
        <property type="nucleotide sequence ID" value="XM_007687689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCU7"/>
    <dbReference type="GeneID" id="19127492"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89500"/>
    <dbReference type="HOGENOM" id="CLU_2120673_0_0_1"/>
    <dbReference type="OrthoDB" id="3682867at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="114" mass="12322" checksum="BAA02F24C2D88C28" modified="2014-04-16" version="1">MAWRTCTWGTSDALARVGDSLTPAARAELWAKRPGQRSEGQRAVVIMAPYTRTLLDTTSLFTPPFAASRWRACQGPATPKQALPQCPSSLHPPYSPPAPYRVSALGKRQGTCPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDK4</accession>
    <name>W6ZDK4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_88616</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins. Involved in mitophagy. Required for the switch to necrotrophic growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The mitochondrial prohibitin complex consists of two subunits (PHB1 and PHB2). The subunits assemble into a membrane-associated ring-shaped supercomplex of approximately 1 mDa. Interacts with ATG24/SNX4; the interaction is direct and plays a role in mitophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the prohibitin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685507.1">
        <property type="nucleotide sequence ID" value="XM_007687317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDK4"/>
    <dbReference type="STRING" id="930090.W6ZDK4"/>
    <dbReference type="GeneID" id="19127315"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88616"/>
    <dbReference type="eggNOG" id="KOG3090">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047969_0_2_1"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035632">
        <property type="term" value="C:mitochondrial prohibitin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF1">
        <property type="entry name" value="PROHIBITIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="9">
        <location>
            <begin position="56"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00053189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00066275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="312" mass="34498" checksum="EC2DEEA29AA655C7" modified="2014-04-16" version="1">MASPDPKEAWSRLQNELTRRSARFGGAGGGGPPRGVFGGLGGLLLVGGGIWMANNALFNVDGGHRAIKYTRIGGVQKEIYSEGTHFRIPWFETPITYDVRAKPRNVASLTGTKDLQMVNITCRVLSRPRVEALPQIYRTLGTDYDERVLPSIVNEVLKSVVAQFNASQLITQRENVSRLVRDNLVRRAARFNIMLDDVSLTHLAFSPEFTAAVEAKQVAQQEAQRAAFVVDKARQEKQATVVRAQGEARSAELIGDAIKKSRSYVDLREFENARSIASILQQSSNKIYLDSKGLGLDISQSNADKEQRANRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE82</accession>
    <name>W6ZE82_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_87522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685171.1">
        <property type="nucleotide sequence ID" value="XM_007686981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE82"/>
    <dbReference type="GeneID" id="19127085"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87522"/>
    <dbReference type="HOGENOM" id="CLU_3013860_0_0_1"/>
    <dbReference type="OrthoDB" id="3659055at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="56" mass="6399" checksum="6D06A5EC39EB6D3F" modified="2014-04-16" version="1">MQSTCLGEWTSHSTKALLQCLWVADTGPGRSSTLWWEECHCDAERLTRFLQSATRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEG1</accession>
    <name>W6ZEG1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_29402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964081">
        <property type="protein sequence ID" value="EUC41911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691574.1">
        <property type="nucleotide sequence ID" value="XM_007693384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEG1"/>
    <dbReference type="STRING" id="930090.W6ZEG1"/>
    <dbReference type="GeneID" id="19121499"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29402"/>
    <dbReference type="eggNOG" id="ENOG502TGHY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103817_0_0_1"/>
    <dbReference type="OrthoDB" id="3692311at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="171" mass="18605" checksum="00574B7614B5F110" modified="2014-04-16" version="1">MTITTRTVSPTTTSPSSESKFTVSLAEPPYRTVTEKVTGTSTAAPSMPSHGRSTPVAAIVGAVLGSVIFCALLLAIFFFIRKRKLTKVYKAPAYPSPCVGGDMTPQLSSKASSQFQKMVAELYRSDTMETSEPPQLDSREILPQFHRRDSTGRFAELPAEPLPWPGHSVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEJ2</accession>
    <name>W6ZEJ2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_34165</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685132.1">
        <property type="nucleotide sequence ID" value="XM_007686942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEJ2"/>
    <dbReference type="STRING" id="930090.W6ZEJ2"/>
    <dbReference type="GeneID" id="19122494"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34165"/>
    <dbReference type="eggNOG" id="KOG4245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039329_5_0_1"/>
    <dbReference type="OrthoDB" id="432010at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF30">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="87"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC48288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="327" mass="36614" checksum="E8CB806F99ACAF07" modified="2014-04-16" version="1">MALNCKTTETIKFDRLKQKIAFQEAVGSPYFIAHGTHPPTLMITGMKDGLPPYNTPFLEDIDDRLNNVEKRLESMDASGIAYAIVSLTCSGVEGILYPDEAVELAKKTNDAIYEIYVKVHPTRFGFFCSVAIQKPEEAAKELGAKGALFNGFTNIHKGDVSNVHYLDDPVCEPLWEKVSELNVPMYAAYGFGVETAGHSLRIMCSGILGRYKNVQIILGHCAESLPFLAHRIDHRMAIGIMGNNGPYENSIMYCLQKNFYATLAGVRRESTMRNTIDEMGESCVLFSVDYPYESNEDATDWFDGIQMNENTREAIGWENAKRIFKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF52</accession>
    <name>W6ZF52_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_32274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683030.1">
        <property type="nucleotide sequence ID" value="XM_007684840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF52"/>
    <dbReference type="GeneID" id="19122064"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32274"/>
    <dbReference type="eggNOG" id="ENOG502QX3S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026522_0_0_1"/>
    <dbReference type="OrthoDB" id="7700931at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF125">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN YLR001C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889972" description="FAS1 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="114"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="245"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="455" mass="51251" checksum="7ABCADA14C030899" modified="2014-04-16" version="1">MRFSRVVPLLPLATAFVITEPDVFSKIEKSGRRLVDNAQTVLDDALGKVKDGAQDASSKFHHIGYDVEAWLEGEEFDDKVIDLDHPHGPPHHGKPDHPPHHGPPHHPPHHEKPNRTVYELINESKYTTKLAKLINEFDDVVELLNGTAANYTIFAPTDEAFEKIPKHHPEPSKEFLKEILLYHVIDSLYPAGRVLHSFTIPTLYTTSKNLGHAQRLTPRVTFKGPTINYYSRLVAVNIFGTNGVVHGVDHILVPPPNVATIIDLLPGSFSTLELALTKTGIYDWLNTTQYEHNGGTFFAPSNYAWKKLGTRANAFLFSKYGEKYLKALLEYHLVVDQTLYTDAFIDGSGDDDDDDDESTKDRPDYYHYDLPTVLDDKYLAVDVTCYGPFAEIRINRFSRVTIHDGIASDGVIQVVSDVLIPPKNAGGEEVFWEGEELDVEDLKERLEPFVDNMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF68</accession>
    <name>W6ZF68_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_93671</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963971">
        <property type="protein sequence ID" value="EUC46149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687376.1">
        <property type="nucleotide sequence ID" value="XM_007689186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF68"/>
    <dbReference type="GeneID" id="19128304"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93671"/>
    <dbReference type="eggNOG" id="ENOG502QXB0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012260_2_0_1"/>
    <dbReference type="OrthoDB" id="447251at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF9">
        <property type="entry name" value="PAS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="455"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="29"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="574"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="815" mass="89834" checksum="38C9648218303A53" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFR9</accession>
    <name>W6ZFR9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_8050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964064">
        <property type="protein sequence ID" value="EUC42351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691117.1">
        <property type="nucleotide sequence ID" value="XM_007692927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFR9"/>
    <dbReference type="STRING" id="930090.W6ZFR9"/>
    <dbReference type="GeneID" id="19125680"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8050"/>
    <dbReference type="eggNOG" id="KOG0098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_23_1_1"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001537">
        <property type="entry name" value="Secretion related GTPase SrgD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="254" mass="27353" checksum="F8CA766EF7A672D1" modified="2014-04-16" version="1">MAQPWDYIAKIVSLGDSGCGKSSLTVRLCEGRFSPHHDVTIGVEFGSRIVPVGPPASYALNINNPSAAAQAQAPVSPAKQKQEQKHMKLSLWDTAGQETYKSITRSYFRGASGALLVFDISRKNTFLSATSWLHDLRQIAEEGIVVVLVGNKSDLASEATANKRQVSREEAEEWCKANGVMQYVETSAKSGEGVERAFLEVAERIYQNIEAGKYDLNDRRSGVKGPGGGGASRGGVNLNDASKKGKQQGWGSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFW1</accession>
    <name>W6ZFW1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_23298</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684501.1">
        <property type="nucleotide sequence ID" value="XM_007686311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFW1"/>
    <dbReference type="GeneID" id="19120411"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23298"/>
    <dbReference type="eggNOG" id="KOG3855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_9_4_1"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="11"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="6">
        <location>
            <begin position="535"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="596" mass="66229" checksum="0A2D4AB4E0B42281" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG10</accession>
    <name>W6ZG10_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_103504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964061">
        <property type="protein sequence ID" value="EUC42441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691042.1">
        <property type="nucleotide sequence ID" value="XM_007692852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG10"/>
    <dbReference type="GeneID" id="19118319"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103504"/>
    <dbReference type="HOGENOM" id="CLU_054809_0_0_1"/>
    <dbReference type="OrthoDB" id="3695549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="415" mass="45577" checksum="5F7A51F77A20C131" modified="2014-04-16" version="1">MSPMPPDMLAHPSNQNAIPHFPSSYTTIYPTQTNTEHLREPTTLPRPSHSRTAHTTEPNHFPIPQIQGIVPGFRRAHPSTHISHSLSLSTPTTRDILQTLHATKSPTTTKTTTKQSSYPRPSPPNFLHPFPIVPYTTLPCTTNHTLYRDKAMADAPPLSLSTTLPIGLKLLFLGTLCAAVLGLAWVVVVWCVVCLPQRRDGDGDQEAQLHHKETWQSDQGRQWSDKEVKPSSKVQRNRSNHTQRSLGEADEGMKDMREMGDVANPFADHANMNEDEDTSAALSSGVQRPGTSRFRGRKDGAVGSLWNPFLDPPGEGEGSGSGSGGRTDEEWERARAVFFGEVEDARGEIEVEMRDLPCGQVNDVEATALKKGDRRSGFAAVVRRGIEMLDEGVGMVDGVVDDAVAAVARWTDDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG98</accession>
    <name>W6ZG98_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_23292</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684498.1">
        <property type="nucleotide sequence ID" value="XM_007686308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG98"/>
    <dbReference type="GeneID" id="19120408"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23292"/>
    <dbReference type="eggNOG" id="ENOG502QPR4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024588_2_0_1"/>
    <dbReference type="OrthoDB" id="4676at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03884">
        <property type="entry name" value="M20_bAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="ALLANTOATE DEIMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494:SF20">
        <property type="entry name" value="PEPTIDASE M20 DIMERISATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001235">
        <property type="entry name" value="Amidase_carbamoylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="220"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="428" mass="46198" checksum="A02CC79623F742B0" modified="2014-04-16" version="1">MTSSSLKINGDRLNSTLQDTCTQYGALAAPSTGMCRLTLTPEDQAARDWLVSECKSLGCEIKVDQMGNIFAIREGTSKDKKPIGMGSHMDTQPAGGRYDGILGVQAALEVLRTLHENNISTHCPLALINWTNEEGARFPGAMMSSGVWSQHSSTPLSTCWSTLDPDGITMKDALQQINYLGETPCSHLDNPLHCHFELHIEQGPLLERAGKTVGVVETVQGMQWYAIRVLGKEGHSGTTPMPDRSDALVTASRLITAVRDTALHTELGVATVGVIKSDTASQATIPAGVDFIIDIRCSTDALVTQLSTAIFATFDKIIAEETNGTTYKIQRTWGLPESKFHPHCIEAVRGAAVGLVGEDQVMSMMSRAGHDSAWTSRVVPTSMIFVPSRDGISHNPEEYTSPEHCALGAQVLLEAVLAYDEKVAKGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH33</accession>
    <name>W6ZH33_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_84840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684096.1">
        <property type="nucleotide sequence ID" value="XM_007685906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZH33"/>
    <dbReference type="STRING" id="930090.W6ZH33"/>
    <dbReference type="GeneID" id="19126548"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84840"/>
    <dbReference type="eggNOG" id="KOG4210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027451_1_1_1"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF95">
        <property type="entry name" value="NUCLEOLAR PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="122"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="242"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="210"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="366"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="366"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC49340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="443" mass="48945" checksum="03D359AB62CC470B" modified="2014-04-16" version="1">MTSSDEALAVFKKERRERKDKKEKKRSKSESKNEAAEASASEEEAPVKIETPAKKRKRDILPEELEIDINLPEPVSKKAARKAKKAKLNPTPAAEGEEGDAGTKTDGEAKGAKDADGKRSDYGVWIGNLPWSATKDSLRTFLSENSEIASDQITRVHMPPPTKVNPSWTTKPLNKGFAYVDFSTELAMYSAIALTETKMDGRALLIKNAKSFEGRPDKPKTEEGQDTRRAGNADKSGHPPNKRVFIGNLSFDVTKEDLQEHYAQCGDIEDIHMATFEDSGKCKGYAWITFADVESATWAVKGFVFKDAAEFKKKGKKDDSDDEDEDAKPEKKRKWFISKFMGRELRCEFAEDATTRYNKRWGKDRPVKAVDGVNPDRWRNFDQGGGGERKAGRGNNERGGGGGGGGSKRKVDPRTIKSGAAHSSAPRASQAIVESTGKKTTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHB8</accession>
    <name>W6ZHB8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_35549</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686629.1">
        <property type="nucleotide sequence ID" value="XM_007688439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHB8"/>
    <dbReference type="STRING" id="930090.W6ZHB8"/>
    <dbReference type="GeneID" id="19122807"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35549"/>
    <dbReference type="eggNOG" id="KOG1638">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065395_0_0_1"/>
    <dbReference type="OrthoDB" id="5788137at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016636">
        <property type="entry name" value="3-oxo-5-alpha-steroid_4-DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF43">
        <property type="entry name" value="STEROID 5-ALPHA-REDUCTASE DET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015596">
        <property type="entry name" value="5_alpha-SR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="117"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="287" mass="33409" checksum="ED89DBA9017EB0B7" modified="2014-04-16" version="1">MAIVQGWLPPSRENWELLCWIWQFFPLFTLVQWVLDWYPQGKTSVESRFNVNGKIGWATMESVGFIALLYIMIALPKELGIEELPWGNWTMAGCFVIHYLYRALLSPLFLNPSMSPIHLFVWVAAAVFQLCNAISIGGYLAGYGPTSQYEWAARTEWMFVGLVVWCWGLMGNMFHDDDLREIRRAADRRQRKLAKEEGRPVESVDKVYMIPKNGLFKYVLSAHYLCEWIEWAGWWMIGGWKCHPARSFLLNEISTMVPRAVQSKRWYEKKFGKEKLEGRKAVIPGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHJ1</accession>
    <name>W6ZHJ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_102016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964042">
        <property type="protein sequence ID" value="EUC43021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690475.1">
        <property type="nucleotide sequence ID" value="XM_007692285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHJ1"/>
    <dbReference type="GeneID" id="19117993"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102016"/>
    <dbReference type="eggNOG" id="ENOG502QZ63">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049199_0_0_1"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630:SF7">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="38215" checksum="AE2DFACBC571BD12" modified="2014-04-16" version="1">MITTTTKAPTLTLSGVQNVAMKMDGTDAKFGDWRDDLARDGYAVIKGAIPQEKALKYADRMFSWLEGFNLGFDRNDLSTAHKDKLPLINEKGMCIHYAVTHEDFAWDVRGEPGVVSAFEKVYDDKDLIVSFDAINFTFPGRTDIAPNKPWPHQDQNPEKAGFRCLQGLVNLLPNGPDDGGLIVCPGGHLLSEEFHAAMKDEPRIPAWTPEWFGFTENGMKWLADKGLTWTKVCADPGDLLVWDSRTPHYNLASKTHQPRFAIYTCYMPVADASQEDLIRKKDAYERWVGTTHWPNAMHTGSNVATRDGVEDPHNRFEPVNKPVMNERTFKLTGIPYIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI77</accession>
    <name>W6ZI77_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur assembly protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_101481</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the assembly of mitochondrial and cytoplasmic iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690276.1">
        <property type="nucleotide sequence ID" value="XM_007692086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI77"/>
    <dbReference type="STRING" id="930090.W6ZI77"/>
    <dbReference type="GeneID" id="19117876"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101481"/>
    <dbReference type="eggNOG" id="KOG1120">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069054_0_0_1"/>
    <dbReference type="OrthoDB" id="333486at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044572">
        <property type="term" value="P:[4Fe-4S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.300.12:FF:000001">
        <property type="entry name" value="Iron-binding protein IscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050322">
        <property type="entry name" value="Fe-S_cluster_asmbl/transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072:SF41">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="5">
        <location>
            <begin position="142"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00054873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00071673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC43206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="247" mass="27148" checksum="8C2B535E4F4D8A6D" modified="2014-04-16" version="1">MSLPRTTGALVRSSTSFLRFAAPPFAPRRCPQCSRSFASSLPRRQSAKRQMQTATVYQPSSLYPEPPPRNVGVPDTSIAGGATEAKNTTLPQTPPHNRNAASQAEQTTVSIPEGEAQKPQQVANPSKPLRPRRYNFGPRKATIKLSPSAVAHLRELLELPEPKLIRISTKAKGCSGLAYHLEYVDKPSPLDEQVEQDGVKVLIDNKALLNIIGSEMDWLEDKLNERFIFKNPNITEQCGCGESFSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIW2</accession>
    <name>W6ZIW2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683576.1">
        <property type="nucleotide sequence ID" value="XM_007685386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIW2"/>
    <dbReference type="GeneID" id="19126257"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83440"/>
    <dbReference type="HOGENOM" id="CLU_1769070_0_0_1"/>
    <dbReference type="OrthoDB" id="3668416at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887107" evidence="1">
        <location>
            <begin position="18"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="131" mass="14608" checksum="CE4C0612AD473A08" modified="2014-04-16" version="1">MRFLQIIPAVFAASTLAAKFENFVDTSCQRYSADYKLITVAEQEKLIVDSWAKTPTSQETSRAFSPKGSCPSNADDTYKWITVPQWNDVPTRFGRPGGGSIAVVYFNETDTYHVCRYLASVQPNGYAGFCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIY8</accession>
    <name>W6ZIY8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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    </dbReference>
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            <end position="338"/>
        </location>
    </feature>
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        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="707" mass="80855" checksum="06DD4789D2062A74" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ25</accession>
    <name>W6ZJ25_COCMI</name>
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        <recommendedName>
            <fullName evidence="9">DUF3955 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051:SF0">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0813">Transport</keyword>
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            <end position="86"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF13127"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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    <sequence length="480" mass="52888" checksum="ACC2B01999B79F31" modified="2014-04-16" version="1">MIPRREELVETTPISPRISDVSDESAFMRSQDYLDSPATEASQWVDGKDGRGAWSSKVRHAIGIGFLLATVFLWTASNFLASTIFADNSYSKPYFVTYVNTSFFILPLLPMLLHCLWSDYRQPNTARQPRQPFVTHIYNLLQRQTGKWTLLREHESSSSLVPSHESRNDEATEVLLSSSAPGSLNLGSGKDVGHVTDTGGLTLHDTAKLALEFCILWFLANYFAAGCLEYTTVASSTILSSTSSIWTLLLGSIMRVERFTVLKLVGVLASLSGVVLISLVDVSGETDENRGTFPHKTPRELAIGDVMAFVSAVLYGFYTVFMKAKIGDETKVNMPLFFGLVGLANVVLLWPGFIILHLTGIEQFELPPTTRILNIVLINSASSLVSDFCWAYAMFLTSPLVVTVGLSLTIPCSLVGQMLLDAQYASALYWVGAAIMVISFLFINHEDRKDEVQGSADTSARGSFQSVRQSLSRRNSRSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="2">UBA domain-containing protein</fullName>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14308">
        <property type="entry name" value="UBA_Mud1_like"/>
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    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="UBA"/>
    </dbReference>
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        <property type="entry name" value="UBA-like_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="357"/>
        </location>
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            <begin position="579"/>
            <end position="593"/>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="1">YCII-related domain-containing protein</fullName>
        </recommendedName>
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    <gene>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606:SF3">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII-related" evidence="1">
        <location>
            <begin position="12"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="114" mass="12934" checksum="26F589ADF3CD94A1" modified="2014-04-16" version="1">MASTSQQPLQEWLVIVPDYKEALSKRLAVRPKHLEGIKGDREDFWLWGGAMLEEPIQPGDTNPPKMKGSACLIGAATRDEVVERLKKDVYVQEGVWNWDEVQIIPFKSTVRKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJW9</accession>
    <name>W6ZJW9_COCMI</name>
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        <recommendedName>
            <fullName evidence="11">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_1039</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC50318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007684935.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZJW9"/>
    <dbReference type="GeneID" id="19118400"/>
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    <dbReference type="eggNOG" id="KOG1598">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010293_0_2_1"/>
    <dbReference type="OrthoDB" id="511529at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="CYCLIN_TFIIIB90_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.650">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BRF1_TBP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07741">
        <property type="entry name" value="BRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Cyclin-like" evidence="11">
        <location>
            <begin position="131"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="11">
        <location>
            <begin position="234"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="344"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="522"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="590"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="647"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="655"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="690"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC50318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="735" mass="81766" checksum="9D6D4CD2784E4F59" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKC6</accession>
    <name>W6ZKC6_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 131 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_60395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684919.1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_60395"/>
    <dbReference type="eggNOG" id="ENOG502SH6P">
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    <dbReference type="HOGENOM" id="CLU_063723_1_0_1"/>
    <dbReference type="OrthoDB" id="5283326at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612">
        <property type="entry name" value="GH131_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE 131 CATALYTIC N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase 131 catalytic N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="264" mass="29685" checksum="0E9C2B822B28FD7F" modified="2014-04-16" version="1" fragment="single">FDGRIPQNFTGDTFETVKSPFNPKYVLGQNQTWKEVISFPNVEPSMFDRVAGTKPIEVEITDRSIFASSSEGRETALRRAELLVNGKNQTVSGKVTWLFSMRTSPYALNLSHEYLLAFHEAQDFQADFWSLKVGLPMQETLRGPNGAESMLKTGSVIYLQGWKWAKKVQTYFMAPFTSDIWHNFGLYLDFDDNQMQVAYSTGKDGLKIVTPLLANNISGKAPTTLGETHWGLQKRPVGANINNFLFEGLQPHGIRERLVIGGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKY9</accession>
    <name>W6ZKY9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_98648</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689248.1">
        <property type="nucleotide sequence ID" value="XM_007691058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKY9"/>
    <dbReference type="STRING" id="930090.W6ZKY9"/>
    <dbReference type="GeneID" id="19129303"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98648"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF2">
        <property type="entry name" value="AMIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="5">
        <location>
            <begin position="83"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="3">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="216"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC44251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="535" mass="58451" checksum="C48225E3817A24BD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLF7</accession>
    <name>W6ZLF7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682488.1">
        <property type="nucleotide sequence ID" value="XM_007684298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLF7"/>
    <dbReference type="GeneID" id="19124270"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_452"/>
    <dbReference type="HOGENOM" id="CLU_564969_0_0_1"/>
    <dbReference type="OrthoDB" id="3695661at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="226"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="483" mass="55045" checksum="B159F5581C7F73F3" modified="2014-04-16" version="1">MPADVHLIEDEGAYEPVPTKGQNGLRFPVERYLPPNNFINFDDEINYHQKLLYIARNINRNVSCLRCGIPTGQHPKDLGVCQWCGGAADGGHPHRECLWIYANVSFWKSKLKITDPTSGQKSSSWVPVNVRIQPTKKEQTLLAREDPIFLDFPRARESRDMVVPDGANMMQPVLIPRKFKNRDLNRGEKRQRGDDNEASERSTRRPFVSESDKYVELKAALFRELKDELFHELSRMREKIARLSEEVTELRAVTEKNRENQFPSSLLDVSMAGFLLATPSTWKICRPVLATLDGKGTVPADSATSMTSTRTVAALIQASIVPRNNKAHLTQAGVTAEYFRSAVDIKTTPVWIDALYIIDNNITQARAVEKRRKLFDEQRLQSTPKAAVHAAGEQQSFLPMHMKRECSAEPHWPNELSRSSEYGRTENRGTLAQQRNDRINRDQASLRSPPRRGDYSPGNGIDHLKWPIEGTEMEMYFARCRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLK3</accession>
    <name>W6ZLK3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_34087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685024.1">
        <property type="nucleotide sequence ID" value="XM_007686834.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZLK3"/>
    <dbReference type="GeneID" id="19122480"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34087"/>
    <dbReference type="eggNOG" id="KOG0929">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001772_0_0_1"/>
    <dbReference type="OrthoDB" id="2157641at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF373">
        <property type="entry name" value="PH AND SEC7 DOMAIN-CONTAINING PROTEIN C11E3.11C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="831"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="791"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="959"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1096"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1397"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1534"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="540"/>
        </location>
    </feature>
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            <end position="636"/>
        </location>
    </feature>
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        <location>
            <begin position="663"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="696"/>
        </location>
    </feature>
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        <location>
            <begin position="727"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="813"/>
        </location>
    </feature>
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        <location>
            <begin position="1103"/>
            <end position="1117"/>
        </location>
    </feature>
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        <location>
            <begin position="1135"/>
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        <location>
            <begin position="1534"/>
            <end position="1557"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1567"/>
            <end position="1587"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1587" mass="173240" checksum="5152165350D40687" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLU6</accession>
    <name>W6ZLU6_COCMI</name>
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        <recommendedName>
            <fullName evidence="9">Acetate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_80578</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLU6"/>
    <dbReference type="GeneID" id="19125693"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80578"/>
    <dbReference type="eggNOG" id="ENOG502SI7M">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF7">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="94"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="26602" checksum="FB97B778E6BB4451" modified="2014-04-16" version="1">MANSSATDLKSSGHTDIERQVTYEAPVVRAPAPKTLGSGTALPIGVFATTLTALSFSLMEWRGVTTNNVFVANFFFAAAFGKLLACIAFIGMVITAQWELSVGNGFAYTVFSAFGLFYAGYGAILTPSFGIVAAYGDNVKELNNALGFFMISQTVFALVFLVASLPTNLVYIIIFFTVELGFLLIAASYFAVADGHAGASTALKKGGGVFCFLSGLAGWYLEFALLLKDSIVELPLGDTSRFFAKSRKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM26</accession>
    <name>W6ZM26_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_21504</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682330.1">
        <property type="nucleotide sequence ID" value="XM_007684140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM26"/>
    <dbReference type="STRING" id="930090.W6ZM26"/>
    <dbReference type="GeneID" id="19120073"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21504"/>
    <dbReference type="eggNOG" id="KOG1651">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029507_3_1_1"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061692">
        <property type="term" value="P:cellular detoxification of hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000010">
        <property type="entry name" value="Glutathione peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC51120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="168" mass="18971" checksum="2B2BA3A50A9BA09A" modified="2014-04-16" version="1">MASATSFYEFKPKDKKGQPYDLSQLSNKVVLVVNTASKCGFTPQFEGLEKLYKDIKSKYPDDFEILGFPCNQFGGQDPGTNEEIQEFCQVNYGVSFPVLGKIDVNGATADPAFEWLKNEKPGLMGLKRVKWNFEKFLIGRDGKVKGRWASTKKPEDLKAEIEKELSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM83</accession>
    <name>W6ZM83_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_31673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682364.1">
        <property type="nucleotide sequence ID" value="XM_007684174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM83"/>
    <dbReference type="GeneID" id="19121928"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31673"/>
    <dbReference type="HOGENOM" id="CLU_128302_0_0_1"/>
    <dbReference type="OrthoDB" id="10327723at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC51118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="118" mass="13209" checksum="3ED115C5CF7EA76C" modified="2014-04-16" version="1">MVHGLASFGKAYTLITMWCWASLARIHSRMFTAVSRALHFSSESGASRPRDCRFYKHCKGSVLRVSYPGKIILGGKWYPYPVASFGRSIWGCNGGEQKDKKNQTVGKKHMIVARQAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMU7</accession>
    <name>W6ZMU7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_31456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682141.1">
        <property type="nucleotide sequence ID" value="XM_007683951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMU7"/>
    <dbReference type="STRING" id="930090.W6ZMU7"/>
    <dbReference type="GeneID" id="19121874"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31456"/>
    <dbReference type="eggNOG" id="ENOG502QTC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026014_0_0_1"/>
    <dbReference type="OrthoDB" id="2153847at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="364" mass="36143" checksum="B5A5E908E50B0FA2" modified="2014-04-16" version="1">MTKREVPQEHSHRNVNLAVNTILQQNNPAKIQDPVFALLGAAAAAEGAGDIADADCLQLAVADQAFTNAKEAGDVEGMTMALIFRALERNTGSVGLKSVPCESIQAVNPEIAALQQHQDPAADGAQALNKQIAEELARQIASIGGDPSLANEASTFAPGEIGDPTGAGNTCDDATDDAGCINTLGLRVDDLSEAEIAAAVADVKGAANGAANGAAKGAAKGAAADNKAAEEQAVSCGNEAAASAGHAAAAQDNAAAAQDGAAAAKDDAVSSKASADFGNCDPTIVFGLPSDGRKEDAFEPSDLSTFNHGSAQKIAIISNFICSQLANKCDASASAVSTCDAAASAANGLEGQAAATAFNTALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRW0</accession>
    <name>W6ZRW0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_82608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683351.1">
        <property type="nucleotide sequence ID" value="XM_007685161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRW0"/>
    <dbReference type="GeneID" id="19126091"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82608"/>
    <dbReference type="eggNOG" id="ENOG502S1M0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020820_0_0_1"/>
    <dbReference type="OrthoDB" id="3596604at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="558"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="667" mass="74771" checksum="F21EA81AEEF27AC3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSV9</accession>
    <name>W6ZSV9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_4172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686680.1">
        <property type="nucleotide sequence ID" value="XM_007688490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSV9"/>
    <dbReference type="STRING" id="930090.W6ZSV9"/>
    <dbReference type="GeneID" id="19124120"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4172"/>
    <dbReference type="eggNOG" id="KOG0593">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017513_2_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="191"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="622" mass="71447" checksum="E4DE9C9F11905426" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSW8</accession>
    <name>W6ZSW8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">ATCC 44560</strain>
        </source>
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    </dbReference>
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        </source>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
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                <person name="Han J."/>
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            </authorList>
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            <strain evidence="5 6">ATCC 44560</strain>
        </source>
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        <property type="entry name" value="SLIRP/GR-RBP-like"/>
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    <dbReference type="PANTHER" id="PTHR48027">
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
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</entry>
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        <recommendedName>
            <fullName evidence="4">RanBD1 domain-containing protein</fullName>
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            <taxon>Dothideomycetes</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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        <source>
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        </source>
    </reference>
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        <subcellularLocation>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
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        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF142">
        <property type="entry name" value="RAN-BINDING PROTEIN 3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="4">
        <location>
            <begin position="429"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="301"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="392"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="270"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="338"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="404"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC48656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="567" mass="59549" checksum="0E2C3C0AFF95D4A4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYT5</accession>
    <name>W6ZYT5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_2329</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684596.1">
        <property type="nucleotide sequence ID" value="XM_007686406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYT5"/>
    <dbReference type="STRING" id="930090.W6ZYT5"/>
    <dbReference type="GeneID" id="19120407"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2329"/>
    <dbReference type="eggNOG" id="KOG2938">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036838_0_0_1"/>
    <dbReference type="OrthoDB" id="432381at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070635">
        <property type="term" value="F:nicotinamide riboside hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070636">
        <property type="term" value="F:nicotinic acid riboside hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045437">
        <property type="term" value="F:uridine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006216">
        <property type="term" value="P:cytidine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034355">
        <property type="term" value="P:NAD+ biosynthetic process via the salvage pathway"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019358">
        <property type="term" value="P:nicotinate nucleotide salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006218">
        <property type="term" value="P:uridine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02651">
        <property type="entry name" value="nuc_hydro_IU_UC_XIUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF4">
        <property type="entry name" value="URIDINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="10"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC48876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="394" mass="42110" checksum="24E8D0B5904D8CB2" modified="2014-04-16" version="1">MSATASTTPIWLDCDTGHDDAYALLLCAHDPQVELLGVSTVHGNAALDQTTYNTRAILEAIGRRDVKVYSGAAKPIARDAVHAADIHGESGLDGVTLLPVPVEPAATDVDHLEAAYRALIATPPDTAWLVSTGTLTNIGLLFQKYPDLASHIKGLSIMGGAVGGGFTDAPMGKVEGEGERFGNWTPYAEFNIYCDPEASHLIFSNPILRPKTTLIPLDLTHQVLGTRQIRQTLLYGSSIFDSSPPPSKDDPTPTPTPLRALFTQIMSFFASTYADVFSITQGPPLHDPLAVSAAYNPRIFDDRDGERFLVDIVTDGLHSSDKALVGELGRTKVTKLPPGQPGCRIPRAVDLEAFWGSIESALARADGVGALPWVEAHELERVGVFEGVGKPGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3H7</accession>
    <name>W7A3H7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_81567</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682895.1">
        <property type="nucleotide sequence ID" value="XM_007684705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3H7"/>
    <dbReference type="GeneID" id="19125899"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81567"/>
    <dbReference type="eggNOG" id="ENOG502SNI4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_5_1"/>
    <dbReference type="OrthoDB" id="5022096at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="50"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="419" mass="46752" checksum="190EAE8523D92B70" modified="2014-04-16" version="1">MAYHHLISRQGWEPPPTPARSPEYMAENHAPHLMAVEGPLFALSTTAVLLRFYVRIFMLKTFGWDDIMMLIAVCISITTLGLFLTVINLGLGKHAEAFPVENIFPFFKYMYFYSILIIAGYSFIKLSIGLFLLRLADRTRWRPFLIGMLIFIVIFTLGSTFAIIFQCIPIRAGWDYTMRPPTGTAKCYDATIFKNVGVFNSCINIATDLIFALIPIPMVWKLQVTIQTRIGLAAILGLGLFASAIAIYKTPMQANFFKVKDWSGDGSWYYIWQQVEMHVGIIAACLPTIKPLFASFFGQVRSIATRGQTTGSNGLNSTPFRSRGYTKQSEQQNSDSFVMKNMSEGSQSIGRDPYGEDTVLAKDTYTVIAGRGKSGLERMGSPAGESDDSIESYEARCGPRRSVQRGLTIVKTTEVAISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3X7</accession>
    <name>W7A3X7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Scavenger mRNA decapping enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_31931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIT family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682683.1">
        <property type="nucleotide sequence ID" value="XM_007684493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3X7"/>
    <dbReference type="STRING" id="930090.W7A3X7"/>
    <dbReference type="GeneID" id="19121992"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31931"/>
    <dbReference type="eggNOG" id="KOG3969">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041045_0_0_1"/>
    <dbReference type="OrthoDB" id="10264956at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000016">
        <property type="entry name" value="Scavenger mRNA decapping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.40">
        <property type="entry name" value="Scavenger mRNA decapping enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008594">
        <property type="entry name" value="DcpS/DCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011145">
        <property type="entry name" value="Scavenger_mRNA_decap_enz_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12978">
        <property type="entry name" value="HISTIDINE TRIAD HIT PROTEIN MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12978:SF0">
        <property type="entry name" value="M7GPPPX DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05652">
        <property type="entry name" value="DcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028973">
        <property type="entry name" value="Scavenger_mRNA_decap_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102860">
        <property type="entry name" value="mRNA decapping enzyme DcpS N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR028973-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="38387" checksum="B4D0AC30BB98AF74" modified="2014-04-16" version="1">MTSTTPPEIAAHVESLIPKFKLTRLLNSDQAGRRISLLGTIDSQPALLIAERAAFDTTPAILEGFSTSLRNIKNLGANDIYAWFLANSNPSTDKDASSPPPPPDFKINLIYPCTDKHVKKYTQQRLRIVTETPEIYTSYIRPYMRAQREKGALNWVYNIIEGRTEQEDVMYRESGSDGFLLLPDLNWDRKTMGSLHLLGIVERRDIWSVRDLTRDMVGWVRHMRQKMIEATVGLYPDIERDELKLYVHYQPTYYHFHIHIVHVSLEAGNTQATGKALGLENIISQLETMASSSSSSSSASPPGMQDASLTYHLGERSDLWEKVYLPLKEGREVNVDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJP3</accession>
    <name>W6YJP3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_111145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964318">
        <property type="protein sequence ID" value="EUC39587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693889.1">
        <property type="nucleotide sequence ID" value="XM_007695699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YJP3"/>
    <dbReference type="GeneID" id="19119720"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111145"/>
    <dbReference type="HOGENOM" id="CLU_2549051_0_0_1"/>
    <dbReference type="OrthoDB" id="3960873at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="83" mass="9512" checksum="A59844606CA40996" modified="2014-04-16" version="1" fragment="single">LYYVHIKSLIDFLVSLLPSDNIYNVPHQRTLELNCLISQATHLIDIRHAIIGATTYLQITRQPWPPPPHMLKDWSPSGTPNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YL10</accession>
    <name>W6YL10_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_110265</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964229">
        <property type="protein sequence ID" value="EUC39887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693594.1">
        <property type="nucleotide sequence ID" value="XM_007695404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YL10"/>
    <dbReference type="GeneID" id="19119571"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110265"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_3_1"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF84">
        <property type="entry name" value="VACUOLAR MEMBRANE AMINO ACID UPTAKE TRANSPORTER FNX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="56"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC39887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="558" mass="59224" checksum="062743CB14284531" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNL5</accession>
    <name>W6YNL5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_107462</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964129">
        <property type="protein sequence ID" value="EUC40947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692534.1">
        <property type="nucleotide sequence ID" value="XM_007694344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNL5"/>
    <dbReference type="STRING" id="930090.W6YNL5"/>
    <dbReference type="GeneID" id="19119053"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107462"/>
    <dbReference type="eggNOG" id="KOG0412">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006939_0_0_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048682">
        <property type="entry name" value="COG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048684">
        <property type="entry name" value="COG4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013167">
        <property type="entry name" value="COG4_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048680">
        <property type="entry name" value="COG4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20662">
        <property type="entry name" value="COG4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08318">
        <property type="entry name" value="COG4_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20663">
        <property type="entry name" value="COG4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00762">
        <property type="entry name" value="Cog4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="COG4 transport protein middle alpha-helical bundle" evidence="10">
        <location>
            <begin position="171"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="331"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1247" mass="138227" checksum="BEEBE26792897D49" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YP82</accession>
    <name>W6YP82_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_10426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964396">
        <property type="protein sequence ID" value="EUC39485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693995.1">
        <property type="nucleotide sequence ID" value="XM_007695805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YP82"/>
    <dbReference type="GeneID" id="19118472"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10426"/>
    <dbReference type="HOGENOM" id="CLU_2867336_0_0_1"/>
    <dbReference type="OrthoDB" id="4072826at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="65" mass="7493" checksum="FECE56E8D1394B56" modified="2014-04-16" version="1">MATTVPSTHSPVKVWTTEPVHQNLDPFSSERLIFRALLDSDFPAYHTTLSQEETMTKKLARSWFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPV8</accession>
    <name>W6YPV8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_111235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964334">
        <property type="protein sequence ID" value="EUC39558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693921.1">
        <property type="nucleotide sequence ID" value="XM_007695731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPV8"/>
    <dbReference type="GeneID" id="19119735"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111235"/>
    <dbReference type="eggNOG" id="ENOG502SSBS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023254_1_0_1"/>
    <dbReference type="OrthoDB" id="4158087at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="46922" checksum="7D5BFF7E3549BA2E" modified="2014-04-16" version="1">MTSQHVQFDFIISDPVSNPKPGKSLQIRSRCMLGRNKREGSRRTQREKRKIANEMLRSASSSRAPGHSNTFSPKPVVKDLIPTRFTARGIDPEAEMLLADAFAFNFLANDVTPLERCTNLDCLESVCFSWLFTDTTFLHSMLCASYAIKDFKSPQSKGSPGVKTTFHLQATLSLLRVKMQKSFAHQDEAVLRVIINLTLLAIGFGDWVTAATHLKGLRGIVQLRGDAAFLAERPTLHFKLDRIDLAWSLASGRKPYFMQPLKSWDCRIRCPYPTLPPDLYQPWAAWDYRIVNVFKDFQNLTLMINRNRLKFLPGRRIPYAWVVQQLRIMYVTGGSEIRQDKSLLLWVLLTASITVAGAHDTWIRDALKTAVTGLEWKYVQAHVSRVMWIEMVHNRTGQKAYDRLSDMKSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ18</accession>
    <name>W6YQ18_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964274">
        <property type="protein sequence ID" value="EUC39705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693777.1">
        <property type="nucleotide sequence ID" value="XM_007695587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ18"/>
    <dbReference type="GeneID" id="19119669"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110783"/>
    <dbReference type="HOGENOM" id="CLU_2711492_0_0_1"/>
    <dbReference type="OrthoDB" id="5135333at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="73" mass="8414" checksum="00EDD2CA068587EB" modified="2014-04-16" version="1" fragment="single">GEECIRPRKRTLYSVQGRHDGFSLQEPGLSGIPNTSPRRFRDWDLADARSAPKPKLDIALHELEERHLILHTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ67</accession>
    <name>W6YQ67_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein mS33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_8749</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS33 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964097">
        <property type="protein sequence ID" value="EUC41552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691920.1">
        <property type="nucleotide sequence ID" value="XM_007693730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ67"/>
    <dbReference type="STRING" id="930090.W6YQ67"/>
    <dbReference type="GeneID" id="19127075"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8749"/>
    <dbReference type="eggNOG" id="KOG4844">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150777_0_0_1"/>
    <dbReference type="OrthoDB" id="2257454at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013219">
        <property type="entry name" value="Ribosomal_mS33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13362">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13362:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08293">
        <property type="entry name" value="MRP-S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="106" mass="12284" checksum="389B8B871CE9E02D" modified="2014-04-16" version="1">MAVPRQRVLDLMRVQCKVFNTTYNPECLRLGSRILHQRLKGPSVASYYPPRIGTIPQLRSLYPEHQIIDEAEEDWLEHLNVAKSRGKGAPKKKRTAAESKKFNKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR04</accession>
    <name>W6YR04_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">cAMP-dependent protein kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_104984</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8 9">Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964082">
        <property type="protein sequence ID" value="EUC41872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691601.1">
        <property type="nucleotide sequence ID" value="XM_007693411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR04"/>
    <dbReference type="STRING" id="930090.W6YR04"/>
    <dbReference type="GeneID" id="19118615"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104984"/>
    <dbReference type="eggNOG" id="KOG1113">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018310_0_1_1"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd12098">
        <property type="entry name" value="DD_R_ScPKA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000039">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000118">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003117">
        <property type="entry name" value="cAMP_dep_PK_reg_su_I/II_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02197">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00394">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0114">cAMP</keyword>
    <keyword evidence="4 9 10" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="203"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="334"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC41872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="460" mass="50165" checksum="B2EBB895DBC7AD23" modified="2014-04-16" version="1">MSLPPDYSNEISTLDREILKHKPHDILQFCANFFNRRLESQRTEYLLSQQHASHQGRAENSFPGSNPFSTSPSSGSTFAKTTMHRLEEEEENDIMTSPTASTFAAVDFARARNNGNLATGGESAFGNFGGFGGSSKNTIIQMPPLVGEGQTFPNNYNTNRRTSVSAESLNPTSSAADNFTPPFHQKTPDQLSRLKSAVSGNFLFSHLDDEQSSMVLGALHEKPIPTKGIKVIQQGDVGDYFYVVEKGSFDIYVNQSGKLEAGAEGAGNKVGTVGPGGSFGELALMYNAPRAATVTSTEPSTLWALDRITFRRILMDSAFQRRRMYEGFLEEVPLLSTLTPYERSKIADALETKKYPPGTTIIQEGDVGESFFLLEAGEAEVFKRGIDGAVNQYQKGDYFGELALLNDAPRAASVISKTEVKVATLGKNGFQRLLGPVEGIMRRNDPTKSVSEGDHVDPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRT4</accession>
    <name>W6YRT4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_41316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964174">
        <property type="protein sequence ID" value="EUC40330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693143.1">
        <property type="nucleotide sequence ID" value="XM_007694953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRT4"/>
    <dbReference type="STRING" id="930090.W6YRT4"/>
    <dbReference type="GeneID" id="19124040"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41316"/>
    <dbReference type="eggNOG" id="ENOG502SRU9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_959716_0_0_1"/>
    <dbReference type="OrthoDB" id="3766406at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="290" mass="32489" checksum="942CF991CCE3760F" modified="2014-04-16" version="1">MAAALPIVVFNFHSGIYVPAVDPAMIVTTVRQRAVSRLKRLFPQLFVLSNSGPCNLPLEIILMIAEYLNKRALKDTDPRFCVLSSCYIPYHYVRLVMNRHVFGPEHGLPLQTLSKRNNYTDHKYGVERSISQHARIFSDELLVLTAVSMTQLRGDLVLLRSYVEFCGGSICQHLTISQGSPDCIPIQFDELPKKGNASGPFPVYRPMYGSCNWFLTYYSINITWQGVGNGYSIGVLWRTMATRDLIEKSRSAYSPQNPPGSIRGKWNEAGGVEEITGGKWRRALRAAGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRU6</accession>
    <name>W6YRU6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="7">2.3.3.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_9873</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="7"/>
    <dbReference type="EMBL" id="KI964186">
        <property type="protein sequence ID" value="EUC40208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693267.1">
        <property type="nucleotide sequence ID" value="XM_007695077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRU6"/>
    <dbReference type="STRING" id="930090.W6YRU6"/>
    <dbReference type="GeneID" id="19129319"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9873"/>
    <dbReference type="eggNOG" id="KOG2367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004588_3_0_1"/>
    <dbReference type="OrthoDB" id="418791at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07942">
        <property type="entry name" value="DRE_TIM_LeuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000045">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.270:FF:000002">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00572">
        <property type="entry name" value="LeuA_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005668">
        <property type="entry name" value="IPM_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054692">
        <property type="entry name" value="LeuA-like_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039371">
        <property type="entry name" value="LeuA_N_DRE-TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00970">
        <property type="entry name" value="leuA_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002991">
        <property type="entry name" value="PRK03739.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46911">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46911:SF1">
        <property type="entry name" value="2-ISOPROPYLMALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22615">
        <property type="entry name" value="IPMS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89000">
        <property type="entry name" value="post-HMGL domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="15">
        <location>
            <begin position="33"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="580"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="594"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC40208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="638" mass="70620" checksum="32011A390D2772BE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSE9</accession>
    <name>W6YSE9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_108527</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964156">
        <property type="protein sequence ID" value="EUC40545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692930.1">
        <property type="nucleotide sequence ID" value="XM_007694740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSE9"/>
    <dbReference type="GeneID" id="19119265"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108527"/>
    <dbReference type="HOGENOM" id="CLU_2984400_0_0_1"/>
    <dbReference type="OrthoDB" id="10396095at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="58" mass="6531" checksum="788D53AA8C2E0B14" modified="2014-04-16" version="1" fragment="single">RYGMHVFVNQTTSGVLSGTVAVMLTSLKRDLSEFIFRPVHTSCLQCIIYTGFPRIIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSH0</accession>
    <name>W6YSH0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_28942</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RENT3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964062">
        <property type="protein sequence ID" value="EUC42397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691060.1">
        <property type="nucleotide sequence ID" value="XM_007692870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSH0"/>
    <dbReference type="STRING" id="930090.W6YSH0"/>
    <dbReference type="GeneID" id="19121410"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28942"/>
    <dbReference type="eggNOG" id="KOG1295">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018549_1_0_1"/>
    <dbReference type="OrthoDB" id="18087at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12455">
        <property type="entry name" value="RRM_like_Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000637">
        <property type="entry name" value="Nonsense-mediated mRNA decay protein Upf3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039722">
        <property type="entry name" value="Upf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005120">
        <property type="entry name" value="UPF3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112:SF0">
        <property type="entry name" value="FI21285P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112">
        <property type="entry name" value="UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03467">
        <property type="entry name" value="Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="477"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="554"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="190"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="385"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="406"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="462"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="579"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="608"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="618" mass="65693" checksum="A4167EFCD94ADDF3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTK7</accession>
    <name>W6YTK7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_102546</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="KI964049">
        <property type="protein sequence ID" value="EUC42792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690707.1">
        <property type="nucleotide sequence ID" value="XM_007692517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTK7"/>
    <dbReference type="STRING" id="930090.W6YTK7"/>
    <dbReference type="GeneID" id="19118103"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102546"/>
    <dbReference type="eggNOG" id="ENOG502QTBT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_8_2_1"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051915">
        <property type="entry name" value="Cellulose_Degrad_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620:SF16">
        <property type="entry name" value="LYSOSOMAL BETA GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620">
        <property type="entry name" value="PERIPLASMIC BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 3 N-terminal" evidence="8">
        <location>
            <begin position="72"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="633" mass="69613" checksum="740B3138B3CF1DC7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV44</accession>
    <name>W6YV44_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF3824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_106238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964104">
        <property type="protein sequence ID" value="EUC41418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692078.1">
        <property type="nucleotide sequence ID" value="XM_007693888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV44"/>
    <dbReference type="STRING" id="930090.W6YV44"/>
    <dbReference type="GeneID" id="19118824"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106238"/>
    <dbReference type="eggNOG" id="ENOG502S1DF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013056_1_0_1"/>
    <dbReference type="OrthoDB" id="5407645at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="599" mass="66966" checksum="84B5F8FC2BFA01ED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVG7</accession>
    <name>W6YVG7_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">ornithine aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ornithine--oxo-acid aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_105910</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="4"/>
    <dbReference type="EMBL" id="KI964098">
        <property type="protein sequence ID" value="EUC41533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691953.1">
        <property type="nucleotide sequence ID" value="XM_007693763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVG7"/>
    <dbReference type="STRING" id="930090.W6YVG7"/>
    <dbReference type="GeneID" id="19118769"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105910"/>
    <dbReference type="eggNOG" id="KOG1402">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_3_1"/>
    <dbReference type="OrthoDB" id="10261433at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:L-arginine catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010121">
        <property type="term" value="P:L-arginine catabolic process to proline via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006591">
        <property type="term" value="P:ornithine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000011">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC41533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="484" mass="52832" checksum="E96F65E4FFBE7106" modified="2014-04-16" version="1">MAPGAVQNDTSSANSNSTTLKPTARSFHPTGTPDPARYHSASSQAAIKSESDFAAHNYHPLPIVFARASGCSVWDPEGKHYLDFLSAYSAVNQGHCHPELVKALTEQASRLTLSSRAFYNDVFPRFAEYATKLFGFDMILPMNTGAEAVETAVKIARKWGYKVKGIPQNEALVFSVQENFHGRTFAAITMSTDPESRENYGPYLPGIGSVCPVTGKPIRYNNVDDVRETLEKHGKNTAAFLVEPIQGEAGIVVPDDSYLREVRALCDKHNVLLICDEIQTGIARTGKMLCHEWSGIKPDLVLLGKAISGGMYPVSCVLGSKEVMLTIEPGTHGSTYGGNPLGSAVAIRALELVEEENMIERAETLGNKFRQGLQDINNPMIKTIRGKGLLNAIVIDESRTNGHSAWDLCMLFKEKGLLVGRALKIMHVKEVDGTDTDGQAKPTHQNIIRLAPPLVITEQEVESALSIIKEAMEELPTLKGKMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW36</accession>
    <name>W6YW36_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_105363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964088">
        <property type="protein sequence ID" value="EUC41753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691743.1">
        <property type="nucleotide sequence ID" value="XM_007693553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW36"/>
    <dbReference type="GeneID" id="19118672"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105363"/>
    <dbReference type="HOGENOM" id="CLU_2903865_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="62" mass="7137" checksum="EB50FDEB3952E309" modified="2014-04-16" version="1">MYHRPKKAYRPSSYENAHTSDGKRRHSDQATYCCCSPPAQARLMRFSIPVDFSVVGLPKQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYD0</accession>
    <name>W6YYD0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_103171</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964056">
        <property type="protein sequence ID" value="EUC42580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690907.1">
        <property type="nucleotide sequence ID" value="XM_007692717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYD0"/>
    <dbReference type="GeneID" id="19118238"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103171"/>
    <dbReference type="eggNOG" id="ENOG502RNYE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_0_1_1"/>
    <dbReference type="OrthoDB" id="9996127at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF9">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886411" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="20"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="60"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="498" mass="54802" checksum="09507CC6371F991F" modified="2014-04-16" version="1">MILIPIIVWLVCAVHRSLANSDDLKQVVLELHPLLSKDAVITFPWDARWDDLQIRGSSPRISPNYNVVVEVATEADVQTIVSLANRFNVPFLAISGGHGWTTTLNELPYGIQINMRKLNTTTLSQDGKTAIVGGGTKQYEITRSLFALGKYAVTGLSNCVSVAGPLLGGGHSLLQGQYGYSVDGLVSARVVLANSEVVEASRTKNADLFWALQGAGHNFGILTSLEVKTYDIPSDWTVYTLIFSSEKVEALFSLVNDFEDPTTERPAKLALTGVFIRLPAVDPINPVVLYTVAYEGSQAQAEPYAARFIALGPIFTKVDIVNYVELYTVTGNNLTSQACTQNENVLGAGVSLPAWDIQGVRKAFTIFGEYTADPRFNTSITLMENYGMQGVRAIDAESTALAPEERELPILASAVIWWAGEDKETTKVAESHIHAMRDALYTGIDKDSSKKRHCYVNYASGDESKPEVYGYNARLERLARLKSEWDPENKFRYYNPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYH2</accession>
    <name>W6YYH2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689063.1">
        <property type="nucleotide sequence ID" value="XM_007690873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYH2"/>
    <dbReference type="STRING" id="930090.W6YYH2"/>
    <dbReference type="GeneID" id="19124902"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6267"/>
    <dbReference type="eggNOG" id="ENOG502RCNY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033907_0_0_1"/>
    <dbReference type="OrthoDB" id="2405944at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053226">
        <property type="entry name" value="Pyrrolopyrazine_biosynth_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48419">
        <property type="entry name" value="SULFOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48419:SF1">
        <property type="entry name" value="SULFOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19798">
        <property type="entry name" value="Sulfotransfer_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="40878" checksum="EC419F400D639590" modified="2014-04-16" version="1">MTSKPIFVATHPRACSTAFERVFMTRHETLQCVHEPFGDAYYFGPERLAERYENDPKARKESGYEESTYRTIFDRIARENSEGKRVFIKDMAQYWIPPSGKPATIAPSLSNYRRGVGTNTTELSPVTTRSDPNKPPYPYDTKGEPGNPTVIPKDLLATYHFTFLIRHPKYSIPSYYRCTIPPLDAMTGFYNFRPDEAGYEELRRLFDFLRSEGQIGPKFAGQTDEAHKEQTNGHTGGVEICVIDADDLLDKPSEMIETFCKTTGIEWDPGMLQWDSEKDQSIAKEAFEKWKGFHEDALDSDRLRARTHKKQPKSDEQMFEEWKEKFGDEGAKTIRDTVAANVEHYEYLKQFAVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYQ4</accession>
    <name>W6YYQ4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_98093</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689002.1">
        <property type="nucleotide sequence ID" value="XM_007690812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYQ4"/>
    <dbReference type="GeneID" id="19129184"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98093"/>
    <dbReference type="eggNOG" id="KOG1153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_4_1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000014">
        <property type="entry name" value="Proteinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF58">
        <property type="entry name" value="ALKALINE PROTEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012565294" description="Peptidase S8/S53 domain-containing protein" evidence="8">
        <location>
            <begin position="16"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="10">
        <location>
            <begin position="53"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="9">
        <location>
            <begin position="136"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="41376" checksum="38DF4116A57861D7" modified="2014-04-16" version="1">MYFLLLSLLASLATATPLVKVPRRSNAIANKWIVKLKDNVATMAVDGVKSALSTEPDYQYSMPGFRGFAGTLSDEEVALLQVSDEIEYIQQDAEVYTTALVKQLNATWGISRISHTKPRETTYLYDSSAGEGTCAYVIDTGVDITHPEFQGRAFFLADLTHEGTFIDGFGHGTHVAGTIGSATWGIAKKTTIFAVRVLDSNGWGTNSDVIAGLEFILRDARERKGTDQCRNGFVVNISLGSEKLPALNDAAAAMVAEDIFLGVAAGNDGVPADDFSPGSEPSVCTVGATAANDTLASWSNHGPRIDVLAPGLGITSTLPNGVVASFSGTSMAAPHVVGLAAYLLGLGSPSKDLCGTIAALAIKNAIDQDTLPKGTPNLLAFNGANASQKHTKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYU5</accession>
    <name>W6YYU5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_37628</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688937.1">
        <property type="nucleotide sequence ID" value="XM_007690747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYU5"/>
    <dbReference type="GeneID" id="19123290"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37628"/>
    <dbReference type="eggNOG" id="ENOG502SMC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_4_1"/>
    <dbReference type="OrthoDB" id="3923077at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="27"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="293"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="302"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="350" mass="39192" checksum="9AC457D08FF98678" modified="2014-04-16" version="1">MGIGPRASEMVRIEVAFLVISWIAVVLRVYVRTSIVKAFGWDDRWMLFAQLMHTTNVGCATGGALTGTGRLAKDLTPGSMMIALRFWWICYWTYCLTMISAKVSLGLSLLRYTPYTHVRSRRMTYFAIWISIVIGAAYGLIAMFQCKPVRFFWTRAIGETGTCIDIHVIMSLTYVMSAIFAASDFSFAILPVFLVRGLTVSRNQKLALIPILSMGCIASSAVIVRLAYVQTFLDPEFLYSTVPIAIWSEIEMSLAITAGSLSTLRPLYRLAAQKFLWRTSLFSNRRSLASLDMTTRPRHSDATNGSSKHNKKTSNTDSCPELERSMARAASEDLELEADHSHRASQKEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYX6</accession>
    <name>W6YYX6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_102708</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964050">
        <property type="protein sequence ID" value="EUC42765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690738.1">
        <property type="nucleotide sequence ID" value="XM_007692548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYX6"/>
    <dbReference type="GeneID" id="19118139"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102708"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_2_0_1"/>
    <dbReference type="OrthoDB" id="1935484at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000247">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000106">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF60">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17160)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="57783" checksum="E3553DA551708584" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ47</accession>
    <name>W6YZ47_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_97648</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase C56 family. HSP31-like subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688853.1">
        <property type="nucleotide sequence ID" value="XM_007690663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ47"/>
    <dbReference type="STRING" id="930090.W6YZ47"/>
    <dbReference type="GeneID" id="19129101"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97648"/>
    <dbReference type="eggNOG" id="ENOG502RZ3Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070319_2_0_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03141">
        <property type="entry name" value="GATase1_Hsp31_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF11">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="6">
        <location>
            <begin position="91"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="229" mass="24056" checksum="8D1BEB6D41B00193" modified="2014-04-16" version="1">MSKPSILFVLTSHNKLGDTGKPTGWYLPELAHPYHVLHNKASITVASPKGGEAPLDPASVEAAKDDVSVAFLKNDEAVWKNTQKLSDFVGKAGDFDAIFYVGGHGPMFDLADDATSQQLIKEFWEAGKIVSAVCHAPAVLYNVKLSDGSLLVAGKEVTAFTNAEEEQVGLTKAVPFLPEDALQKASGGKFVKAAEPWGEKVVVSGKLITGQNPASATGVGEALAKALGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZF3</accession>
    <name>W6YZF3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_7512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964043">
        <property type="protein sequence ID" value="EUC42968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690485.1">
        <property type="nucleotide sequence ID" value="XM_007692295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZF3"/>
    <dbReference type="GeneID" id="19125310"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7512"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_2_1"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19146">
        <property type="entry name" value="AKR_AKR9A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="31"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="390" mass="43632" checksum="4822A8A4C7D9C530" modified="2014-04-16" version="1">MPSPFGDVPKAASLLEFHRVMSPTAGVRVSPLCLGAMNFGDAWQDMMGKCDKKTTFEILDYFYQQGGNFIDTANNYQAEESETWIGEWMKERKVRDEIVLATKFTTCFPDPRNAPRMKVNYGGNSTKSLHVSLEASLKKLQTDYIDLLYVHWWDFTTSIPELMQSLNTAVNSGKVLYLGVSDTPAWIVSKANEYARNHGLRGFSVYQGRWSAAERDFERDIIPMAREEGMALCPWGALGGGHFTTEEKRKNNEQGRNFGPASEKHIAISKKLEAVATQKNTQITSIALAYVRHKYPYVYPIVGGRKIDHLKGNIEALAIELTEEEIDDIDSAVPFDIGFPMNFLFEFGGGKYKHTMTSSDVALAKFASILDSVPVQKGPKPHQLQGYGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZM4</accession>
    <name>W6YZM4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_7468</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
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        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="KI964041">
        <property type="protein sequence ID" value="EUC43065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692227.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6YZM4"/>
    <dbReference type="GeneID" id="19125295"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7468"/>
    <dbReference type="eggNOG" id="KOG0585">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004329_1_1_1"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:protein serine/threonine kinase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:cellular response to glucose starvation"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="P:regulation of cell growth"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Serine/threonine protein kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Prot_kinase_dom"/>
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    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE TOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="330"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="261"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="471"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="759"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="882"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="939"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1043"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1090"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1148"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="475"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="516"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
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            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
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            <end position="915"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <end position="1064"/>
        </location>
    </feature>
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        <location>
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            <end position="1113"/>
        </location>
    </feature>
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            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1209"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
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            <end position="1252"/>
        </location>
    </feature>
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        <location>
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            <end position="1267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
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            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1305"/>
            <end position="1316"/>
        </location>
    </feature>
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        <location>
            <begin position="1337"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1353"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1416" mass="156357" checksum="D2901F58D2A61E9F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0R1</accession>
    <name>W6Z0R1_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_100581</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
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        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
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    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Atg1-like"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
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        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="9">
        <location>
            <begin position="121"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="258"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="598"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="676"/>
            <end position="710"/>
        </location>
    </feature>
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        <location>
            <begin position="731"/>
            <end position="781"/>
        </location>
    </feature>
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        <location>
            <begin position="819"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="554"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
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        <location>
            <begin position="756"/>
            <end position="772"/>
        </location>
    </feature>
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        <location>
            <begin position="819"/>
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        </location>
    </feature>
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        <location>
            <begin position="841"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00030237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1036" mass="115506" checksum="126AEEAA632DC264" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z141</accession>
    <name>W6Z141_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_26316</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
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    <dbReference type="OrthoDB" id="9972683at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="356" mass="39470" checksum="96B98E433117819A" modified="2014-04-16" version="1">MSSDKDYQTYNLGNFKLKSGGEIPDAFIAYKTLGDPSLPAVIYPTWYSGTISDNVWLTGTGKTLDPSKYYIIMPALFGNGQSSSPSNMPALRPFPEVLFYDNVRAQHELVTKHLGIKHARAVLGWSMGAGQTYQWATQFPDFMDLAVPFCGSAKTSLHNQVFLEGVKSSLYAALGTSSAGVSKPDLYTAQGKKVAFSSETREAGLKALGRVYAGWGFSQSFYREKLYQSAPTLGYKDLDDFLVNFWESWALSKDPENMLTMAHTWQAGDCSQQEPYNGDFKKAMEAIKAKTLVLPAKTDLYFPPEDSEIEVQNMRPGVGTLKIFPSIWGHWAGGPGQSTEDVKWLDEQLKVFFADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1B5</accession>
    <name>W6Z1B5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964020">
        <property type="protein sequence ID" value="EUC43735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1B5"/>
    <dbReference type="GeneID" id="19123444"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38328"/>
    <dbReference type="eggNOG" id="ENOG502T4WW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_672811_0_0_1"/>
    <dbReference type="OrthoDB" id="3830006at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="407" mass="46091" checksum="0D7379AD967D6FA9" modified="2014-04-16" version="1">MSTDNPSTLNRLSPDWIRRPLSRRSTSPQKSMSPTTANGFLAPEPTRSNSDESRSPRSSTSGRRGSVREIVNRLRSSSSTSMASNKSQDIDFSEVENWFHGFRKYNQLVCNTISPNQAYPSKEFTKASKALTKNCGGQFIHGLPEAVFDFSLLWCPAGYLTRKDTNEPSWSWSAFSGPVNFPFDPTTCPDVYKTPRGEGEWFRSEVLNYHIGPESAQYTVRREKGSSSLRIKYPPYFHAPRGSDHKTDSNTLRFTASTISADGFSAEQLDHEGKQIPCSHLINEDDQHCGVIMDYESSISQPSSTGPYEFVLLSRNLWRKPCAENRKPAGFNTMHPPGTPIWAEDHFLWDKEVDDFAAEQFEAGPWKMLNVMLIKWVGEHAERVAVARIHEDAWTRRSPVKKDIVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1W3</accession>
    <name>W6Z1W3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_94642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963978">
        <property type="protein sequence ID" value="EUC45732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687729.1">
        <property type="nucleotide sequence ID" value="XM_007689539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1W3"/>
    <dbReference type="GeneID" id="19128489"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94642"/>
    <dbReference type="HOGENOM" id="CLU_983496_0_0_1"/>
    <dbReference type="OrthoDB" id="10540536at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="283" mass="31056" checksum="6D662809134765F9" modified="2014-04-16" version="1">MVGNPPSALSNLPTLHSLHNEPLLRELAVTQALASSLSRDCEKWRTLVEKHSSALEEANKTITAANKKLKDREHIISKLKKGNASLKTQGDTSSTLATSLASTLKETTTSLDSTNKKLEDATAKHDSLALQLQEAKANMTKLRRSDRNKEKTQQQNLHLKALLHRQCAARYNSNNSNDNNTAATLRTAPTTTTATTTRNEDILHSALSAALERIDELETSAHALLDALDEHGDSSNEEEDDEGEHDEADATAKLLEAQVKMDGVLRDRGFAVKKGEWGHLIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1Y3</accession>
    <name>W6Z1Y3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxidase</fullName>
            <ecNumber evidence="14">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_100086</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Forms a one-to-one complex with cytochrome c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="14"/>
    <dbReference type="EMBL" id="KI964021">
        <property type="protein sequence ID" value="EUC43708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689775.1">
        <property type="nucleotide sequence ID" value="XM_007691585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1Y3"/>
    <dbReference type="STRING" id="930090.W6Z1Y3"/>
    <dbReference type="GeneID" id="19117601"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100086"/>
    <dbReference type="eggNOG" id="ENOG502QR1E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036959_1_2_1"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000009">
        <property type="entry name" value="Ascorbate peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000005">
        <property type="entry name" value="Cytochrome c peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 14 16" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="111"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC43708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="373" mass="41571" checksum="149C7A1CE95AE125" modified="2014-04-16" version="1">MASASRSFSRALRTAAPSFRTTATRSSARFVAPTQNVFSNQRRGYASQEDGPDKHEGNPTGLAFGAGALLVGAGAYALYTYKPELFGQTSTKVFTPRFEDYQKVYDTIAKRLEENDSYDDGSYGPVLLRLAWHCSGTYDKLTGTGGSNGATMRFAPEADHGANAGLKAARDFLEPVKQAFPWISYSDLWILGGVCAIQEMQGPKIPYRAGRSDRDVAFCTPDGRLPDATKDSSHIRAIFGRMGFDDRAMVALSGAHALGRCHTDRSGFDGPWTFSPTTLTNDYFKLLLEEKWAYKKWNGPKQFEDVKTKSLMMLPTDMELVKDKSFKQYTQLYAKDSDAFFKDFAEAVTTLFELGVPFQQPEDQRWVFRSSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2W7</accession>
    <name>W6Z2W7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_93870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963972">
        <property type="protein sequence ID" value="EUC46097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687440.1">
        <property type="nucleotide sequence ID" value="XM_007689250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2W7"/>
    <dbReference type="STRING" id="930090.W6Z2W7"/>
    <dbReference type="GeneID" id="19128343"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93870"/>
    <dbReference type="eggNOG" id="ENOG502RZKF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_3_0_1"/>
    <dbReference type="OrthoDB" id="428768at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF8">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="9"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="153" mass="16156" checksum="5750499DDE921C7B" modified="2014-04-16" version="1" fragment="single">VPPAASIAQAGTATCLCGAVHLAFPITTPGLVASFVCYCSDCRKGGVEASIVVKDEYLKHVRGTSNLSSFSQPVSTPSSHGSTTFFCHTCGSNMYRVGAAFPGCAIVRMGAVDDARLVEGRLRPTRELCVKERVSWVGGLKGDEVKRRVGLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z345</accession>
    <name>W6Z345_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enolase-phosphatase E1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_98929</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964010">
        <property type="protein sequence ID" value="EUC44143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689323.1">
        <property type="nucleotide sequence ID" value="XM_007691133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z345"/>
    <dbReference type="STRING" id="930090.W6Z345"/>
    <dbReference type="GeneID" id="19129358"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98929"/>
    <dbReference type="eggNOG" id="KOG2630">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023273_1_1_1"/>
    <dbReference type="OrthoDB" id="272500at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043874">
        <property type="term" value="F:acireductone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023943">
        <property type="entry name" value="Enolase-ppase_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01691">
        <property type="entry name" value="enolase-ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20371">
        <property type="entry name" value="ENOLASE-PHOSPHATASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20371:SF1">
        <property type="entry name" value="ENOLASE-PHOSPHATASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="24162" checksum="B0CE2B0D504881FF" modified="2014-04-16" version="1">MCAASLDRARWSQAEVVLLDIGILARHSWADPNFQSLIAAFPDDTKQSPDALLAHVQDLTRHDIKAVYLKQLQGHLWTTGFRNGHLKTPLFDDVVPTLEAWKAAGKTLAIFSSGSVQAQLQFFSYVKDGDVTRDIKPLFSAHYDTVNAGPKMDKASYEKICSELGKPPSKVVFLTDNVKEAEAAIKANVYAVVVDRPGNAPLSDASKARFPAIERLTDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z393</accession>
    <name>W6Z393_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964010">
        <property type="protein sequence ID" value="EUC44173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689318.1">
        <property type="nucleotide sequence ID" value="XM_007691128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z393"/>
    <dbReference type="STRING" id="930090.W6Z393"/>
    <dbReference type="GeneID" id="19123368"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37979"/>
    <dbReference type="eggNOG" id="ENOG502SBV5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152072_0_0_1"/>
    <dbReference type="OrthoDB" id="2391627at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019182">
        <property type="entry name" value="Cytochrome_b-c1_su10_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254:SF1">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09796">
        <property type="entry name" value="QCR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="101" mass="11176" checksum="F9A3D74821F1BBE6" modified="2014-04-16" version="1">MSSTSFPHHAKTPAAVSMRSSYKAYRSPFGPQYTIPKNYHGITVGTVARYGTLAAGFGGVAGFFALFFFAEVPKVRDDIMKKIPVLDKFFTHEIPPEDNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3E0</accession>
    <name>W6Z3E0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_4643</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 10">Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Vacuole membrane</location>
            <topology evidence="1 10">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the beta-catenin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687200.1">
        <property type="nucleotide sequence ID" value="XM_007689010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3E0"/>
    <dbReference type="STRING" id="930090.W6Z3E0"/>
    <dbReference type="GeneID" id="19124319"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4643"/>
    <dbReference type="eggNOG" id="KOG4224">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021483_0_0_1"/>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071563">
        <property type="term" value="C:Myo2p-Vac17p-Vac8p transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051656">
        <property type="term" value="P:establishment of organelle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061724">
        <property type="term" value="P:lipophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000425">
        <property type="term" value="P:pexophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903044">
        <property type="term" value="P:protein localization to membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034497">
        <property type="term" value="P:protein localization to phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031503">
        <property type="term" value="P:protein-containing complex localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034517">
        <property type="term" value="P:ribophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000011">
        <property type="term" value="P:vacuole inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000243">
        <property type="entry name" value="Putative Vacuolar protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000095">
        <property type="entry name" value="Vacuolar protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0926">Vacuole</keyword>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="91"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="132"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="173"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="214"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="257"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="298"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="339"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU369097"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="562" mass="61161" checksum="44CFBD1411C1CD05" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3W5</accession>
    <name>W6Z3W5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPPDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_35928</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC46442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007688845.1"/>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:protein deubiquitination"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF80">
        <property type="entry name" value="IP06716P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="5">
        <location>
            <begin position="26"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="270" mass="29819" checksum="AAD1B79D897177D9" modified="2014-04-16" version="1">MASTTRPKPARTSSNHHRNTLSMQRTEITINVYDLLPPGKISSILWAIGSSLLHSGVVIGDREYAYGGHDRRDLTGVYWTKPGLEPPGGTFKQAILHGFSFRPAEELDVIIQEASHEFQGTSYNLLTKNCNHFTSYLCEKLTGRPAPGYLNRAASIGVALPCVVPREWIAPPDYDTADGELLDEEFEDEGSSMLRHDRERERARTAQETRGWENTSNSAGSNRSSQGGARGHIRNETRNLAPRLVSIAETDSSGRAIPPAERAPLPRNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4Y3</accession>
    <name>W6Z4Y3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_97276</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688703.1">
        <property type="nucleotide sequence ID" value="XM_007690513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4Y3"/>
    <dbReference type="STRING" id="930090.W6Z4Y3"/>
    <dbReference type="GeneID" id="19129027"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97276"/>
    <dbReference type="eggNOG" id="KOG0937">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026996_0_0_1"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030665">
        <property type="term" value="C:clathrin-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09250">
        <property type="entry name" value="AP-1_Mu1_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14835">
        <property type="entry name" value="AP1_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000006">
        <property type="entry name" value="AP-1 complex subunit mu-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="8">
        <location>
            <begin position="166"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="445" mass="50291" checksum="5174055C7724EF99" modified="2014-04-16" version="1">MASAVFFLDLKGKTLLARNYRGDIPMSAVEKFPVLLSEAEDESSAVPPCFSSEGINYLYIRHNNLYLLALTKRNTNAAEILLFLHKVVEVFTEYFKELEEESIRDNFVVIYELLDEMMDFGYPQTTETKILQEYITQESHKLEIARPPIAVTNAVSWRSEGIRYRKNEVFLDVIESLNLLVSATGSVLRSEILGAVKMKCYLSGMPELRLGLNDKAMFESTGRATRGKAVEMEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTQVKPLIWVECIVESHSGSRIEYMLKARAQFKRRSTANNVQISIPVPEDADTPRFRTNIGTVHYAPETSSIVWKIKQFGGGKEFLMRAELGLPSVRGDDEKGGGMMGGFGGSMGGVGAGKAKRPINVKFEIPYFTTSGIQVRYLKIIEPKLQYPSLPWVRYITQSGDIAVRLPDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5E3</accession>
    <name>W6Z5E3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_102578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964049">
        <property type="protein sequence ID" value="EUC42784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690704.1">
        <property type="nucleotide sequence ID" value="XM_007692514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5E3"/>
    <dbReference type="STRING" id="930090.W6Z5E3"/>
    <dbReference type="GeneID" id="19118108"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102578"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009043_1_0_1"/>
    <dbReference type="OrthoDB" id="438641at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="300"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="378"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="661" mass="73899" checksum="49E4A790034DADC0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5F5</accession>
    <name>W6Z5F5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_26595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963989">
        <property type="protein sequence ID" value="EUC45185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688283.1">
        <property type="nucleotide sequence ID" value="XM_007690093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5F5"/>
    <dbReference type="GeneID" id="19120958"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26595"/>
    <dbReference type="HOGENOM" id="CLU_1464605_0_0_1"/>
    <dbReference type="OrthoDB" id="3695288at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="187"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="219" mass="24269" checksum="6AACC6A3D02151A1" modified="2014-04-16" version="1">MAYNQSTHGHLPSWPSDNTRSQNDPFYQPSAVSNLVESPLQTATISEFQGEAQSWDLQTCTYATPSYEVYPPDTIFQQPIPEQEIPHSTAFPSTTYPPLRSQPTSPSPSPPSQTHFSYYQYVTTPPNHHANSILTISPTLFSLPIRHAPRAPLPHSHTSNLLLLLLLNLPSPTDPACTGPARARGRYKCVSEGCERVYARSDGLRVHVRRVHGGKKKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5M4</accession>
    <name>W6Z5M4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_5471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688167.1">
        <property type="nucleotide sequence ID" value="XM_007689977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5M4"/>
    <dbReference type="GeneID" id="19124628"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5471"/>
    <dbReference type="HOGENOM" id="CLU_1415984_0_0_1"/>
    <dbReference type="OrthoDB" id="3687129at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="166" mass="19523" checksum="4086CB0D113DD2F9" modified="2014-04-16" version="1">MSPTDSLPTTPHLQPNLPKPQDILVPYLITEIEEYLAEAMERLNAKSKTERLKSRFKKLWWIMTPITIFKSTNENSLRPHSYLWYKVRDRWQQWATNPYNLHPIWHLFIMILLLFWIVGSSLLSWFEAGADTGTVAVARLCRGFLGSVPPMIQFLLFLYPPLFVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z606</accession>
    <name>W6Z606_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_102073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964043">
        <property type="protein sequence ID" value="EUC42994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690520.1">
        <property type="nucleotide sequence ID" value="XM_007692330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z606"/>
    <dbReference type="STRING" id="930090.W6Z606"/>
    <dbReference type="GeneID" id="19118004"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102073"/>
    <dbReference type="eggNOG" id="ENOG502S5YK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060781_1_0_1"/>
    <dbReference type="OrthoDB" id="4505928at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42070">
        <property type="entry name" value="FILAMENT ASSOCIATED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G06630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42070:SF1">
        <property type="entry name" value="FILAMENT ASSOCIATED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G06630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="31025" checksum="795D6C98EDA1CE97" modified="2014-04-16" version="1">MSDSRISQKAQHLARIRDNQRRSRARRKEYLQELETKLRTYEQIGIEASSEIQSAARTVLEENRKLKAILRDQGMSEQEVSAALENTPDQHSKQIPAASRLSAMLEGKTKPDPTASTTTYIASHAKPMLIPRHTPPVQTISSLPPRSTDFSYDDSPSPGSIVSAMSTPPPSSYSTTFYAAPSTPPGTEIKIEDVTYDYPYNRPYNSSWTHSGDFGYPADPFNYYNRSTCVEAANIVSTARSDPGTELDTGMGYRYPDQYGQMNNAALLMNGYSHHPTAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6M3</accession>
    <name>W6Z6M3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">U3 small nucleolar RNA-associated protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_5178</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
            <location evidence="1 12">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the HEATR1/UTP10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687808.1">
        <property type="nucleotide sequence ID" value="XM_007689618.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z6M3"/>
    <dbReference type="GeneID" id="19124520"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5178"/>
    <dbReference type="eggNOG" id="KOG1837">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001128_3_1_1"/>
    <dbReference type="OrthoDB" id="31183at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012954">
        <property type="entry name" value="BP28_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056473">
        <property type="entry name" value="HEAT_Utp10/HEAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022125">
        <property type="entry name" value="U3snoRNP10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040191">
        <property type="entry name" value="UTP10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457">
        <property type="entry name" value="BAP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08146">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23243">
        <property type="entry name" value="HEAT_HEATR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12397">
        <property type="entry name" value="U3snoRNP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01036">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 12" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6 12" id="KW-0698">rRNA processing</keyword>
    <feature type="repeat" description="HEAT" evidence="11">
        <location>
            <begin position="571"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="BP28 C-terminal" evidence="14">
        <location>
            <begin position="1485"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="856"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC45650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1766" mass="195752" checksum="0E3B91316F2A5F94" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z730</accession>
    <name>W6Z730_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_3496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685901.1">
        <property type="nucleotide sequence ID" value="XM_007687711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z730"/>
    <dbReference type="STRING" id="930090.W6Z730"/>
    <dbReference type="GeneID" id="19122674"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3496"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_1"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19077">
        <property type="entry name" value="AKR_AKR8A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF78">
        <property type="entry name" value="PYRIDOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="12"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="330" mass="35827" checksum="4BEC6675B0DC2813" modified="2014-04-16" version="1">MPQLVGKTVGPVGYGLMGLTWRPDPPSKEQSLEAMRTALSLGANNWNGGELYGTPERNSLHLLNEYFTKYPEDAEKVVLSIKGGLKKGQLTPDGSRENVRRSIDECLRVLDGKKSLDLFECARVDPNTPIQDTVGYIAEYVKEGKLGGISLSEVGAQSIRKAHSVHPISAVEVEFSLWSTDILENGVAATCAELGIPVIAYSPLGRGFLTGKYKKHSDIEPGSILHHMPRFQPEVFDENIKLLHAVEDLAKSKGATPAQIAIGWVLAHSGAKGMPTIIPIPGATTSQRIEENLKPAKLNDEDMKALDEILKKIPVIGGRYNEAQAALLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7H7</accession>
    <name>W6Z7H7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="11">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_31228</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="11"/>
    <dbReference type="EMBL" id="KI964291">
        <property type="protein sequence ID" value="EUC39651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693829.1">
        <property type="nucleotide sequence ID" value="XM_007695639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7H7"/>
    <dbReference type="STRING" id="930090.W6Z7H7"/>
    <dbReference type="GeneID" id="19121825"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31228"/>
    <dbReference type="eggNOG" id="KOG3288">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049327_0_0_1"/>
    <dbReference type="OrthoDB" id="65596at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22745">
        <property type="entry name" value="OTU_OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.80:FF:000016">
        <property type="entry name" value="Putative ubiquitin thioesterase otu1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048857">
        <property type="entry name" value="OTU1_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057766">
        <property type="entry name" value="Znf-C2H2_OTU1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF0">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21403">
        <property type="entry name" value="OTU1_UBXL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24560">
        <property type="entry name" value="zf-C2H2_OTU1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="OTU" evidence="13">
        <location>
            <begin position="128"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="81"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC39651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="328" mass="36375" checksum="E72BA8B5923CA72D" modified="2014-04-16" version="1">MPIRLRLRAPNGTHTLSLDDNAAVSDLLSSISEKTELPLFELKWNHPPQPLDPSLYGMSTLLKDIDLKLNGASIIVIGKATGDPSERKAEQEAQSATSQSAPLSLQRKQNSALKDTPEVPVPERAGTIVLRVMPDDNSCMFRALGSAVLSDSLDSMTELRSMVAQAIQRDPEQYNEAILQRSPDEYCKWISYSDSWGGGIELSILSQEFDIEIASVNVQDNRVDRFNEGRPRRCILVYSGIHYDTIALVPRGVSPQDPSQDIKLFDANDDVVLEAARELCRQLQKQHYYTDTQKFDIKCNTCGWKGAGERGAIQHATETGHSDFGEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7P2</accession>
    <name>W6Z7P2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor-like 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_6974</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964024">
        <property type="protein sequence ID" value="EUC43599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689861.1">
        <property type="nucleotide sequence ID" value="XM_007691671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7P2"/>
    <dbReference type="STRING" id="930090.W6Z7P2"/>
    <dbReference type="GeneID" id="19125139"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6974"/>
    <dbReference type="eggNOG" id="KOG0467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_3_1_1"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16268">
        <property type="entry name" value="EF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000006">
        <property type="entry name" value="Elongation factor like GTPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1430.10:FF:000002">
        <property type="entry name" value="Elongation factor like GTPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056752">
        <property type="entry name" value="EFL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF3">
        <property type="entry name" value="ELONGATION FACTOR-LIKE GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25118">
        <property type="entry name" value="EFL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC43599.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1098" mass="120012" checksum="F4A67C7A14E53450" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="Lowry S."/>
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                <person name="Han J."/>
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                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC46060.1"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="45270" checksum="A3934C8C0F89072D" modified="2014-04-16" version="1">MVAHRRGPWSQHEDQWLVNLVARNGPHNWVRISQEIGSRSPKQCRERYHQNLKPSLNHDPITGEEGELIEKMVAEMGKRWAEIARRLKGRSDNAVKNWWNGGQNRRKRNPERADQRPRDYMHQAQPGFHYPLPSTHPHHEEHHHMTPRHDQQRHDSHRPSVHSPHGLKLPQPQRFEPYPAPRPQPLDLATYGSHAAVRARGFETPMPSPSGYSIVSADGAPSLITDTGSESRSPRGAASPPDMTLAPLVGSREERKNSSTRYLPATGFAPEDDSSSDPYRRRGSLQLPPLHRNEAQASKAAPSFREPNYERPQPPQLLTQPTPQLTHHHSMPQSAPTSVPQRPLPPFHSLAEPRLPLPHSTSASSSPASRQLPSPYVLPSMPAEARSAPVSPKDRMSLRNIM</sequence>
</entry>
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    <accession>W6Z886</accession>
    <name>W6Z886_COCMI</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="86" mass="9811" checksum="AA61A2E1118C5E5B" modified="2014-04-16" version="1">MASDSSPSNRSSQPLLATDSIHSLCRHRALPVHSSFLYPHILAFFEWCLSRAFHTHPIGSPLHPLRCEKNVVHHIWGLHVSYYPSK</sequence>
</entry>
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    <accession>W6Z8I0</accession>
    <name>W6Z8I0_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">PSP1 C-terminal domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="3" type="ORF">COCMIDRAFT_99827</name>
    </gene>
    <organism evidence="3 4">
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689668.1">
        <property type="nucleotide sequence ID" value="XM_007691478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8I0"/>
    <dbReference type="GeneID" id="19129544"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99827"/>
    <dbReference type="eggNOG" id="KOG4679">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011715_0_0_1"/>
    <dbReference type="OrthoDB" id="243127at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047767">
        <property type="entry name" value="PSP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007557">
        <property type="entry name" value="PSP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43830">
        <property type="entry name" value="PROTEIN PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43830:SF3">
        <property type="entry name" value="PROTEIN PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04468">
        <property type="entry name" value="PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51411">
        <property type="entry name" value="PSP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP1 C-terminal" evidence="2">
        <location>
            <begin position="571"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="902" mass="97885" checksum="B713AE6A7013AFDA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8S4</accession>
    <name>W6Z8S4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ornithine decarboxylase antizyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_88031</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with ODC and thereby sterically blocks ODC homodimerization.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ODC antizyme family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685341.1">
        <property type="nucleotide sequence ID" value="XM_007687151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8S4"/>
    <dbReference type="STRING" id="930090.W6Z8S4"/>
    <dbReference type="GeneID" id="19127185"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88031"/>
    <dbReference type="eggNOG" id="ENOG502S3W3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086393_0_1_1"/>
    <dbReference type="OrthoDB" id="5959761at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008073">
        <property type="term" value="F:ornithine decarboxylase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045732">
        <property type="term" value="P:positive regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0075523">
        <property type="term" value="P:viral translational frameshifting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002993">
        <property type="entry name" value="ODC_AZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038581">
        <property type="entry name" value="ODC_AZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10279">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE ANTIZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10279:SF10">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE ANTIZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02100">
        <property type="entry name" value="ODC_AZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0688">Ribosomal frameshifting</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="274" mass="30334" checksum="DC88BBEDEECEFD9B" modified="2014-04-16" version="1">MAMSKRNSSSMSSSSSIHSYSSASNVRASCYAVDASTASLQGFHYSTTPVNQGIPSPPSSPPLAARHATTAKNGKARRGGAAYTITEECERLFCETLRSVFLGEGSQHHQDSLVMGMSYIDTPANTAITNDYGIDVRRYSDSSTDSDVSEMVRFEEHKGAITNYIEMWDYVGGVMFRGFVVEREEERSMFVFFDEAVIGADLKAGLMALLELCEIDYFSCSRLVLCIDRHSDQVARNNLTKDLGWIGFGLITLDDFSQGEKLTSDKWLFMDMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8X0</accession>
    <name>W6Z8X0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_35954</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687038.1">
        <property type="nucleotide sequence ID" value="XM_007688848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8X0"/>
    <dbReference type="STRING" id="930090.W6Z8X0"/>
    <dbReference type="GeneID" id="19122904"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35954"/>
    <dbReference type="eggNOG" id="KOG0610">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_84_4_1"/>
    <dbReference type="OrthoDB" id="432483at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05574">
        <property type="entry name" value="STKc_phototropin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000121">
        <property type="entry name" value="Serine/threonine-protein kinase nrc-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000078">
        <property type="entry name" value="Serine/threonine-protein kinase nrc-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="264"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="55"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="196"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="625"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
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        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="627"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC46470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="656" mass="72195" checksum="99A2F8518A73D821" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8X2</accession>
    <name>W6Z8X2_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_93490</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 21">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.</text>
    </comment>
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    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8X2"/>
    <dbReference type="STRING" id="930090.W6Z8X2"/>
    <dbReference type="GeneID" id="19128276"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93490"/>
    <dbReference type="eggNOG" id="KOG0328">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_0_1"/>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DEAD_ATP_HELICASE"/>
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    </dbReference>
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        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="56"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="237"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00024310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
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            <dbReference type="ARBA" id="ARBA00037945"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC46213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="399" mass="45425" checksum="DC3A84E7F9D07DEA" modified="2014-04-16" version="1">MADGIDRNADDKMEFSTSKEVTVAPTFEAMHLKENLLRGIYAYGYESPSAVQSRAIVQVCKGRDTIAQAQSGTGKTATFSISILQVIDTAVRETQALVLSPTRELATQIQQVIMGLGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVSGTPGRVADMIRRRNLRTRNIKMLVLDEADELLNRGFREQIYDVYRYLPPATQVVVVSATLPYDVLEMTTKFMTDPVRILVKRDELTLEGLKQYFIAIEKEEWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGDMPQRERDSIMQDFRQANSRVLISTDVWARGIDVQQVSLVINYDLPSNRENYIHRIGRSGRFGRKGVAINFVTQDDVRILRDIELYYSTQIDEMPMNVADLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA42</accession>
    <name>W6ZA42_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_86749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA42"/>
    <dbReference type="GeneID" id="19126922"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86749"/>
    <dbReference type="eggNOG" id="ENOG502SRDH">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_278613_0_0_1"/>
    <dbReference type="OrthoDB" id="3946750at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="869"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
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        <location>
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            <end position="472"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48617.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1138" mass="126532" checksum="8C49014293FEE9D1" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6ZAJ0</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
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        </recommendedName>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF12">
        <property type="entry name" value="EUKARYOTIC INITIATION FACTOR 4B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="146"/>
        </location>
    </feature>
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        <location>
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            <end position="40"/>
        </location>
    </feature>
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        </location>
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            <end position="206"/>
        </location>
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            <end position="18"/>
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    </feature>
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            <end position="28"/>
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    </feature>
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        </location>
    </feature>
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            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="206" mass="22973" checksum="03206F5C5D8968EB" modified="2014-04-16" version="1">MSDVEAEQKREEDERLDTAEDPNEEEEISAMRRRVQEMEEEAQKLRQMQQAIDNERHEMRESKEDVDARSVFVGNVDYGASPEEIQAHFQSIGSINRVTILLDKFTGHPKGYAYVEFTEPHLVNEALVLDNSQFRNRNLKVVPKRTNLPGMTRGGRGGRGGGRGGYGGRGSPYGRGGFNSYGAPPRGGGYRGGYRGGRGGSAYRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBJ1</accession>
    <name>W6ZBJ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylglucosaminylphosphatidylinositol deacetylase</fullName>
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        </recommendedName>
    </protein>
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    </gene>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIGL family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688017.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZBJ1"/>
    <dbReference type="GeneID" id="19127717"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90591"/>
    <dbReference type="eggNOG" id="KOG3332">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034979_0_0_1"/>
    <dbReference type="OrthoDB" id="440160at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000225">
        <property type="term" value="F:N-acetylglucosaminylphosphatidylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993:SF11">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="279" mass="31129" checksum="645B2675F7E747DF" modified="2014-04-16" version="1">MNWTVWASVPLLVFAFWMYTSTLSASFPTLHNKRILLLIAHPDDEAMFFAPALLALTRPEHGNHVKILCLSSGDADGLGHVRKKELVKSGLQLGIRSEDDILVVEDKNFPDSMTVTWHPRLISNLLTTAFAPGMSSISSKDAPQATIDAIITFDAHGISGHPNHKSLHAGAHSFLKALMHRHSGWECPVKLYTLTTIPIFRKYLGLFDAPATIIGAMLQKKQLGGFPTPLLFASSPIGYRTAQKAMTTAHESQMRWFRWGWITLSRYMVLNELKLEKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBZ6</accession>
    <name>W6ZBZ6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_90437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686197.1">
        <property type="nucleotide sequence ID" value="XM_007688007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBZ6"/>
    <dbReference type="GeneID" id="19127684"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90437"/>
    <dbReference type="eggNOG" id="ENOG502S6G6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063278_0_0_1"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="43352" checksum="B5B51070A1B8AC16" modified="2014-04-16" version="1">MAATTLSPRSSEHQSSISNMISRLLSKKKTTSKRRDSQEEQEQDTRPQLIHAPVPLILPEHQETLLKLGWTTITFPEISPTTQSPDSLSGIPPPGPHPLQTAYQDLFCAGQAFFNLPDSEKHQWKHRLGSEEGWSKIPGEKEFITLRSLAYCPEILSAPAQRYWELVGQHCSNTLGRISTALGLPDGECEGLRQFVGPCARMPVEEEGKTATMLRLFRYEGWEEKVVAEAHADLGLISMVVGDTPGLEVWDGANWFDVEREVERKGGKGATMLVGRQLERLTNERLRAGGHRVVAYGEPRGMSSGGGIDGVEKRYRHSIVFVLRAHESTQIDSDALETRITGRWRQPMKGVTAGALYEMIRSQCFNINVEKEERNAQRRKLAEAKGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC02</accession>
    <name>W6ZC02_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_96859</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688562.1">
        <property type="nucleotide sequence ID" value="XM_007690372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC02"/>
    <dbReference type="GeneID" id="19128930"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96859"/>
    <dbReference type="eggNOG" id="KOG1153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_4_1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000014">
        <property type="entry name" value="Proteinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF58">
        <property type="entry name" value="ALKALINE PROTEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889897" description="Peptidase S8/S53 domain-containing protein" evidence="7">
        <location>
            <begin position="22"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="149"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="405" mass="41948" checksum="5F74BCEF25392120" modified="2014-04-16" version="1">MHSFKAVLALGALLPAFFAQASKIIRTRNEHTIPGSWVARIEENEVLEAVLSSVLDAAGIQSKETYSVGGVKGFTFDADDTILDMLESMGAIKSVEPDYKMYASVPVGSLRARQTNGTLTTQKGSPYGLGRISHREPGIRDYVFDSSAGEDTFIYVIDTGVNTEHTEFGGRATLGKSFIAGSDGEDDQGHGTHCSGTAAGTTFGVAKKANIIGVKVLGADGSGSNSGVLRGIQWAVDDATEKGHINRTVLSMSLGGPFSQTTNDAIQSAVEAGAFVAAAAGNEGENASNSSPASAPQACTVGSTNERDLKSSFSNFGKLVDIFAPGEKIQSAWIGSSTATNTISGTSMACPHIAGLAAYLIALEGPRSPTALCKRIQELATKDAITNLRAGEGSPNLIAYNGNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC74</accession>
    <name>W6ZC74_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fork-head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_84687</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684125.1">
        <property type="nucleotide sequence ID" value="XM_007685935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC74"/>
    <dbReference type="STRING" id="930090.W6ZC74"/>
    <dbReference type="GeneID" id="19126510"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84687"/>
    <dbReference type="eggNOG" id="KOG2294">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007090_1_0_1"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
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    <dbReference type="CDD" id="cd22701">
        <property type="entry name" value="FHA_FKH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000208">
        <property type="entry name" value="Fork head protein homolog 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000030">
        <property type="entry name" value="Forkhead box protein K2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FHA_dom"/>
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    </dbReference>
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        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
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    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FORK HEAD PROTEIN HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="155"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="9">
        <location>
            <begin position="382"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="382"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="276"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="510"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="591"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="690"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="827"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="730"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="770"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC49392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="859" mass="93962" checksum="95541ED0F1A12006" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCB7</accession>
    <name>W6ZCB7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_84548</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 70 family.</text>
    </comment>
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        <property type="nucleotide sequence ID" value="XM_007685805.1"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="ASKHA_NBD_HSP70_HYOU1"/>
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    </dbReference>
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        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000039">
        <property type="entry name" value="Hsp70 family chaperone Lhs1/Orp150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000004">
        <property type="entry name" value="hypoxia up-regulated protein 1"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ATPase_NBD"/>
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    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
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    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF3">
        <property type="entry name" value="HYPOXIA UP-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="HEATSHOCK70"/>
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    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886855" evidence="9">
        <location>
            <begin position="34"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="603"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="804"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="857"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="905"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="613"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="804"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="864"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="920"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="937"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC49447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1016" mass="111009" checksum="105D5E18FAA35CC3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCG3</accession>
    <name>W6ZCG3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_33135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683978.1">
        <property type="nucleotide sequence ID" value="XM_007685788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCG3"/>
    <dbReference type="GeneID" id="19122250"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33135"/>
    <dbReference type="HOGENOM" id="CLU_1834999_0_0_1"/>
    <dbReference type="OrthoDB" id="3687473at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="141" mass="15446" checksum="093A0D1331FA3A96" modified="2014-04-16" version="1">MPPSCRHDGHEYRQLAMDEVISHPYSDLLSRPGSPDDVPLAHLVAAQTYLEDSDASCTGEAPPSYAVAVRQSYRDTLIQHIPAGQEGYGHVDDESEMGIDMERPDDVRYSVERIAAMFVVAFVLLVVSGVLGWMVLSGALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCM2</accession>
    <name>W6ZCM2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_89451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685777.1">
        <property type="nucleotide sequence ID" value="XM_007687587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCM2"/>
    <dbReference type="GeneID" id="19127483"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89451"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="1669814at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000245">
        <property type="entry name" value="Short chain dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="4">
        <location>
            <begin position="15"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="266" mass="28642" checksum="0170A40FD22D614A" modified="2014-04-16" version="1">MSATRGLPEFSLAGKVILVSGGARGLGLTQAEALLEAGARVYALDRLPEPSADFGPIAERAKKDLGTSLEYRQIDVRDVKKLNEIVDDIANKEGRLDGLIAAAGIQQETPALEYTAEDANRMFEVNITGSMMTAQAAAKQMIKFGNGGSIVLIASMSGTVANRGLICSAYNASKAGVLQLARNLASEWGEHKIRVNTISPGYIVTAMVEELFKQYPERRETWPTQNMLGRLSKPEEYRGAAVFLLSDASSFMTGSDLRIDGGHSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDH6</accession>
    <name>W6ZDH6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963983">
        <property type="protein sequence ID" value="EUC45514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688009.1">
        <property type="nucleotide sequence ID" value="XM_007689819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDH6"/>
    <dbReference type="STRING" id="930090.W6ZDH6"/>
    <dbReference type="GeneID" id="19128638"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95350"/>
    <dbReference type="eggNOG" id="ENOG502RXJG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056749_0_0_1"/>
    <dbReference type="OrthoDB" id="2106152at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40470">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G15850)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40470:SF1">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G15850)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="38192" checksum="3E41DF5181C998AD" modified="2014-04-16" version="1">MHRRFEHQPDKGGFMGSAKSLLPLPFAQPAATKPTPDDSPAPSNITSSSKDPYKAAKEALDRDGFVVLSASLFPSFDLDALRAAATRMTTAARAGKWPYIRTLPKQFPPWPQDPSDGIWGVQHLLHPSNPDHLVFAKSYFDSELLKYVAALIGCGEDDLTMELYNMLVRPDKEFSLRWHRDDIAATATAEEELERLQKPGHHAQWNLALYDDNSLVLVPGSHKRARTDVERSADPYEPNMPNQITVKLKAGEVAFYNNNILHRGVYDCNKERMTLHGSIGTPLAGSQRARNVLQHGVGEWAKEYDFEGFEPGMAERAKKMRERLVEMGEKSGDVGFFSKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE52</accession>
    <name>W6ZE52_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nuclear architecture-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_22257</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683262.1">
        <property type="nucleotide sequence ID" value="XM_007685072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE52"/>
    <dbReference type="STRING" id="930090.W6ZE52"/>
    <dbReference type="GeneID" id="19120215"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22257"/>
    <dbReference type="eggNOG" id="KOG2439">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018240_0_1_1"/>
    <dbReference type="OrthoDB" id="10253113at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.950.10">
        <property type="entry name" value="Fe-only Hydrogenase (Larger Subunit), Chain L, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
        <property type="entry name" value="NITRATE, FORMATE, IRON DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="Fe-only hydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron hydrogenase large subunit C-terminal" evidence="7">
        <location>
            <begin position="133"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="621" mass="66431" checksum="4E45117C763CB50F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEJ9</accession>
    <name>W6ZEJ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase C15, pyroglutamyl peptidase I-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_87368</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C15 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685070.1">
        <property type="nucleotide sequence ID" value="XM_007686880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEJ9"/>
    <dbReference type="STRING" id="930090.W6ZEJ9"/>
    <dbReference type="GeneID" id="19127047"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87368"/>
    <dbReference type="eggNOG" id="KOG4755">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043960_0_0_1"/>
    <dbReference type="OrthoDB" id="407146at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="entry name" value="Peptidase C15, pyroglutamyl peptidase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402:SF1">
        <property type="entry name" value="PYROGLUTAMYL-PEPTIDASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="30486" checksum="562139E81ACF186A" modified="2014-04-16" version="1">MAPSYAAPQPPSEQGEKPVTVLVTGFGPFLTRFPKNSSWEIASTLPSLLPSSPTNKTPIHIHVHHEPIRVAYATVLNLIPTLLPPGNPMNPSPDIILHIGLAAGRNYYAIEQGSRSRGYGNIADVDRQRFDDESAELQFPASKFPSMLSTGFDTTDVLACWKESLKSPSSSSVSEIGSTKGPDVRISTDAGNFLCGFIYYNSLAHYYSIKEDERPVIFLHVPDLTSSEEKLREGWEVTVALIKALGESRRKAGGVVVDRERGGQEAQNGTDGVQTDNNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZES2</accession>
    <name>W6ZES2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alcohol dehydrogenase-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_39870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964076">
        <property type="protein sequence ID" value="EUC42021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691459.1">
        <property type="nucleotide sequence ID" value="XM_007693269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZES2"/>
    <dbReference type="GeneID" id="19123765"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39870"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_16_2_1"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052585">
        <property type="entry name" value="Lipid_raft_assoc_Zn_ADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482:SF2">
        <property type="entry name" value="ZINC-BINDING DEHYDROGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="71"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="323"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="324"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="442" mass="47668" checksum="E5CD1E1EBA538308" modified="2014-04-16" version="1">MESTKKRTRSSAAQSPSRSSPGKRARTQNQFQQRTLVSLPPSEQHALLLHAARQPYDLTTSHATPAIKLGNELLIKVEAIGLNPIDWKAPDFGFGIPTLPYIAGREFAGTVIKVGDETSSRLKPGDVVTVPSTDYRDLRKAAYQQYSIASSFNTIRIPKDISINSGSILGVAFVSAILALGICMGVNFSSIENGPDLLKMVRDLNPEVLPADIRQECLSSISHTERANPGDFLVVWGGSSTCAHVAKQLARLAGLKIISVVDTAKHGLRLSNTDHIRSDLVVDSHDPQRAIQIIRASTGNSARFGFDTIGKETATHLLHSLAHPSEHAKHLDRAGAKPPTPPSTPLGESPQITRSHLVGMTGLPKKDVPAGVALHSVPIKLYHEVPEVGEEISAWCERLLIKGLLVPPDVVGVVKGLGEINEGLNRMRRREISGGRLVAVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF03</accession>
    <name>W6ZF03_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_34139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
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            <end position="128"/>
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    <sequence length="165" mass="18312" checksum="6489B77A643034F9" modified="2014-04-16" version="1">MYWEKSYARRRADRLPVLVTAPLPNDNGPLGRRTLSGHSCALCGGARHPPVSQGLDGTSSVLTRHVPIQAVQAEITRPLLLSLLYTSGPPGPDAERLDRPRPPQGPDSTRYGSSSRAGNHKRHQPSTWHLRAFTYASRRQWGVPSNSSQRMAVENRLTLWIMTTI</sequence>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
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        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48518.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="775" mass="87201" checksum="55EDC251BE2EDC01" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6ZF72</accession>
    <name>W6ZF72_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
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        <name evidence="10" type="ORF">COCMIDRAFT_932</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
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        <text evidence="2">Probable zinc protease.</text>
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    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
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    <dbReference type="OrthoDB" id="5951731at2759"/>
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    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ZnMc_ADAM_fungal"/>
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        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
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    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Disintegrin_dom"/>
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        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
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        <property type="entry name" value="ZnMc_ADAM_fungal"/>
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        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
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    </dbReference>
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        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Disintegrin"/>
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        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
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    </dbReference>
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        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
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    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886804" description="Disintegrin and metalloproteinase domain-containing protein B" evidence="7">
        <location>
            <begin position="22"/>
            <end position="810"/>
        </location>
    </feature>
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        <location>
            <begin position="698"/>
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            <begin position="271"/>
            <end position="487"/>
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    </feature>
    <feature type="domain" description="Disintegrin" evidence="8">
        <location>
            <begin position="512"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="733"/>
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    </feature>
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            <end position="776"/>
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        <location>
            <position position="424"/>
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        <ligand>
            <name>Zn(2+)</name>
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        <location>
            <position position="428"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="434"/>
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        <ligand>
            <name>Zn(2+)</name>
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            <note>catalytic</note>
        </ligand>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00074021"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="810" mass="87281" checksum="D6F23A11B7C57C98" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFA8</accession>
    <name>W6ZFA8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_81323</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682873.1">
        <property type="nucleotide sequence ID" value="XM_007684683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFA8"/>
    <dbReference type="STRING" id="930090.W6ZFA8"/>
    <dbReference type="GeneID" id="19125849"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81323"/>
    <dbReference type="eggNOG" id="ENOG502RYCG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016574_7_2_1"/>
    <dbReference type="OrthoDB" id="4132249at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF18">
        <property type="entry name" value="MALTOSE FERMENTATION REGULATORY PROTEIN MAL13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="511"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="557" mass="61537" checksum="E062690124BBB5B8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFL7</accession>
    <name>W6ZFL7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cell wall hydroxyproline-rich glycoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_103959</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964067">
        <property type="protein sequence ID" value="EUC42281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691225.1">
        <property type="nucleotide sequence ID" value="XM_007693035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFL7"/>
    <dbReference type="STRING" id="930090.W6ZFL7"/>
    <dbReference type="GeneID" id="19118411"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103959"/>
    <dbReference type="eggNOG" id="ENOG502QQ8K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_23_1_1"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051582">
        <property type="entry name" value="LRR_extensin-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32093">
        <property type="entry name" value="LEUCINE-RICH REPEAT EXTENSIN-LIKE PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32093:SF128">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING N-TERMINAL PLANT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0379">Hydroxylation</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012745751" description="Cell wall hydroxyproline-rich glycoprotein" evidence="10">
        <location>
            <begin position="16"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="11">
        <location>
            <begin position="43"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC42281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="306" mass="32754" checksum="C9BE262F1F76E0C6" modified="2014-04-16" version="1">MLTLVLSGFIALAQAAPAQKVASPNGAANIPANLLRDLHTAKEFANHVSGPQNFLSNWTAEGSNLCNWNGFYCDIVPDTNATGLASIDFNQFGLTGNLKLTGFIDKLPDLALLHINGNSFSGDVPDFSGLRYLYEIDLSDNKFSGPFPQSVLKINQLTFLDLRFNQFYGPIPDNVFTAYPSLEALFLNDNKFSGRIPNTIGSFAGEYLVLANNNLSGSIRDSLASANPLKEFIASGNQLSGSIPGAIGRLPNLHLFDVSNNKLTGTVPEELCASKSLTSIVLTGNKLSKNLGPICQASKAKGILQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGB5</accession>
    <name>W6ZGB5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP:AMP phosphotransferase, mitochondrial</fullName>
            <ecNumber evidence="5">2.7.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Adenylate kinase 3</fullName>
            <shortName evidence="5">AK 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ADK2</name>
        <name evidence="8" type="ORF">COCMIDRAFT_80531</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:13749"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adenylate kinase family. AK3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.10" evidence="5"/>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682567.1">
        <property type="nucleotide sequence ID" value="XM_007684377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGB5"/>
    <dbReference type="STRING" id="930090.W6ZGB5"/>
    <dbReference type="GeneID" id="19125689"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80531"/>
    <dbReference type="eggNOG" id="KOG3078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032354_1_1_1"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046899">
        <property type="term" value="F:nucleoside triphosphate adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006172">
        <property type="term" value="P:ADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046039">
        <property type="term" value="P:GTP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046041">
        <property type="term" value="P:ITP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03169">
        <property type="entry name" value="Adenylate_kinase_AK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028586">
        <property type="entry name" value="AK3/Ak4_mitochondrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="7">
        <location>
            <begin position="175"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="5">
        <location>
            <begin position="40"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="5">
        <location>
            <begin position="174"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="19"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="67"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="267" mass="29801" checksum="3C649E43DD21F5AA" modified="2014-04-16" version="1">MHIPSLARAARIILVGAPGVGKGTQTERLMNKFSQLSAISSGDLLRKNVRERTPLGIKAESTMKSGKLVPDTMILRLIVNELTTRGWIRDNALRPYALNFSSMDMADTTVDSVMIPSEVRAPRYTFSNHPSASFILDGFPRTAVQAIQLDNIVPINMVVHLNTPSDIIIDRICNRWVHEPSGRVYNTTFNAPKVPGKDDVTGEPLTRRADDDPEVWKARLQSFKETSEPLLEHYDKLGVLWTVNGNSSDEISPKLFNEFGKRFGAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHB6</accession>
    <name>W6ZHB6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_33356</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684196.1">
        <property type="nucleotide sequence ID" value="XM_007686006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHB6"/>
    <dbReference type="STRING" id="930090.W6ZHB6"/>
    <dbReference type="GeneID" id="19122306"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33356"/>
    <dbReference type="eggNOG" id="KOG3502">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_178987_1_0_1"/>
    <dbReference type="OrthoDB" id="10258930at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000025">
        <property type="entry name" value="40S ribosomal protein S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC49303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="7712" checksum="F1FC790DA44E1FB5" modified="2014-04-16" version="1">MDSAKAPVKLVKVTRVLGRTGSRGGVTQCRVEFMDDQTRSIIRNVKGPVRENDILCLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHC9</accession>
    <name>W6ZHC9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbohydrate esterase family 12 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_85132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684257.1">
        <property type="nucleotide sequence ID" value="XM_007686067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHC9"/>
    <dbReference type="STRING" id="930090.W6ZHC9"/>
    <dbReference type="GeneID" id="19126610"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85132"/>
    <dbReference type="eggNOG" id="ENOG502SBFA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065859_0_0_1"/>
    <dbReference type="OrthoDB" id="2141316at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037459">
        <property type="entry name" value="RhgT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695:SF1">
        <property type="entry name" value="RHAMNOGALACTURONAN ACETYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886857" evidence="3">
        <location>
            <begin position="19"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="4">
        <location>
            <begin position="33"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC49318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="267" mass="28013" checksum="00ED4B05A3847FB7" modified="2014-04-16" version="1">MYTPTLISTIALVATVAAAPSNTLNKRARTAYFAGDSTMANGNNVITGWGAFTSYTLTIPSVNKAIGGRSSRSYTVEGRFDEIANLIQPGDIVTMEFGHNDGGSLSSSDNGRSVCPGTGSEICNSTYNGQKVQVRTYNWYLTEAGKKFIAKGAKVIVSSQTPNNPWESGSFQYGDGGRFVGYARDVAKALGSNATFVDHGKYTADMFKGLGKAGTDALFVAGDHTHTNAKGADAVAKAFFKAVQCAGGSFFQGSIRNATDSIPGTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI74</accession>
    <name>W6ZI74_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 76 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690262.1">
        <property type="nucleotide sequence ID" value="XM_007692072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI74"/>
    <dbReference type="STRING" id="930090.W6ZI74"/>
    <dbReference type="GeneID" id="19123553"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38807"/>
    <dbReference type="eggNOG" id="ENOG502S9QC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028686_0_0_1"/>
    <dbReference type="OrthoDB" id="9984024at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053169">
        <property type="entry name" value="MUG_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791:SF1">
        <property type="entry name" value="ENDO MANNANASE, GH76 FAMILY (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887513" evidence="1">
        <location>
            <begin position="20"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="352" mass="38986" checksum="C26C26AD69B94C54" modified="2014-04-16" version="1">MRYLQVLLLPVAFFSFTCADFTDDAIASIQTLQKTWYNFNTGLWDDFWWQSGNILEAIAQFGIEDPDFKDVAANIVANTYAKSPDQHGAKQWTNKFYDDMGWWAMAWIASYDLTGDKKYLNSAKSIFQDMTSGWNTPCGGGIWWSEDRDYIAAIANELFLAVAAHLANRCSGQERLDYLNWADREWEWFSNSGLINSDGLINDGIDPATCKNNGGTTFTYNQGIILAGLSELSRAKSDPSLVDRAYDIFNAVSKHLTDPSGILTEPVSGALDPVASQFKGAFGRGLLTLYQYKPRKEVKQFFMINANAARSARKGNGGVIPGRWQGDSSDGNTCTLASGIDILVAAAYAEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ13</accession>
    <name>W6ZJ13_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sorting nexin MVP1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Sorting nexin mvp1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_83303</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for vacuolar protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683595.1">
        <property type="nucleotide sequence ID" value="XM_007685405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ13"/>
    <dbReference type="STRING" id="930090.W6ZJ13"/>
    <dbReference type="GeneID" id="19126228"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83303"/>
    <dbReference type="eggNOG" id="KOG2273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009058_1_0_1"/>
    <dbReference type="OrthoDB" id="10064318at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07597">
        <property type="entry name" value="BAR_SNX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06866">
        <property type="entry name" value="PX_SNX8_Mvp1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000037">
        <property type="entry name" value="Sorting nexin mvp-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000072">
        <property type="entry name" value="Sorting nexin MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028662">
        <property type="entry name" value="SNX8/Mvp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035704">
        <property type="entry name" value="SNX8/Mvp1_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045734">
        <property type="entry name" value="Snx8_BAR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554:SF1">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19566">
        <property type="entry name" value="Snx8_BAR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="358"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="162"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="177"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="258"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00072009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC49988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="735" mass="80846" checksum="A8199CF26BF03B3C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJW6</accession>
    <name>W6ZJW6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_68950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683227.1">
        <property type="nucleotide sequence ID" value="XM_007685037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJW6"/>
    <dbReference type="STRING" id="930090.W6ZJW6"/>
    <dbReference type="GeneID" id="19125120"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_68950"/>
    <dbReference type="eggNOG" id="KOG3497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143122_2_1_1"/>
    <dbReference type="OrthoDB" id="10258858at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000024">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00250">
        <property type="entry name" value="RNApol_arch_Rpo10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003089">
        <property type="entry name" value="PRK04016.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF3">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="74" mass="8497" checksum="D9329D52C12DCA3D" modified="2014-04-16" version="1" fragment="single">MIVPIRCFSCGKVTGDLWEKYMALLSDGMEEAEALDSVGLQRYCCRRMILTHVDLIEKLLKYNASEREQARAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK20</accession>
    <name>W6ZK20_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_871</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTH2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682957.1">
        <property type="nucleotide sequence ID" value="XM_007684767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK20"/>
    <dbReference type="STRING" id="930090.W6ZK20"/>
    <dbReference type="GeneID" id="19126984"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_871"/>
    <dbReference type="eggNOG" id="KOG3282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073661_0_3_1"/>
    <dbReference type="OrthoDB" id="1733656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02430">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1490.10:FF:000001">
        <property type="entry name" value="Peptidyl-tRNA hydrolase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003314">
        <property type="entry name" value="PRK04322.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649:SF11">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="193" mass="20345" checksum="45B1B394EAF20D84" modified="2014-04-16" version="1">MSESSQPSTANIAAACAILAGVTGYMLGQAKSLGFFGGSPISQPVKSKKEKADDSEDESSDDEKDSTPADFPGQEECKMVLVVRTDLGMTKGKIGAQCGHATLACYKHFLRTSPNSNILKRWERLGQAKVALQVKSEEELELLQAQALSLGLVAHIIHDAGRTQIASGSATVLGIGPAPKSVIDQVTGHLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL17</accession>
    <name>W6ZL17_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear rim protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_37843</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964007">
        <property type="protein sequence ID" value="EUC44291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL17"/>
    <dbReference type="STRING" id="930090.W6ZL17"/>
    <dbReference type="GeneID" id="19123333"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37843"/>
    <dbReference type="eggNOG" id="ENOG502S7S0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044030_1_0_1"/>
    <dbReference type="OrthoDB" id="3363151at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043007">
        <property type="term" value="P:maintenance of rDNA"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007096">
        <property type="term" value="P:regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018819">
        <property type="entry name" value="Nur1/Mug154"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28293">
        <property type="entry name" value="NUCLEAR RIM PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28293:SF1">
        <property type="entry name" value="NUCLEAR RIM PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10332">
        <property type="entry name" value="DUF2418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="397"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
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            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="406"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="52914" checksum="F1F6C82533DBE952" modified="2014-04-16" version="1">MPRLVRRAPLAERIKAYTDPSDWLIWISEELNSSDWEDFASSYSLYIGFGANLLFVLAQANSGASAASDDDGVFNEVEGPGWLKSTLSLLVMVLGGISFVNAWLVWGKRRYYRLFEQKVDVAPRTPSAKRVRVDSSPAAASPMQFVRNLVQNNAADRAHPIEGRDVWEVAVWDPNPLCLKLFCLFSPLHVVLYFLNLPVGPLDPSPSVRVTTTILIGAVLSLQLWWLQSSFCQQIKDNALISRQVLHEYDSKFVHPSLQKPCRDVGVQTISKNRNLDSSVGVKGSSDDLASEIVTYTPKTVINRTFRTNPNASYASQYDPDNARSTSNTPSLRRRDSNPQYATTSTGTDADIFSPIRSSQPPNPFRQAPTISRNNIDTKVNDGGYLGINTHAASPLRKSTSAAFGRDGERSANRGRDSLGGAFERRASPSKKDVSPLKRISLGNAERERSERSLGQTDRLGRSTGFGGLNLSKREGGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL24</accession>
    <name>W6ZL24_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_80911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684555.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZL24"/>
    <dbReference type="GeneID" id="19125764"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80911"/>
    <dbReference type="eggNOG" id="KOG0928">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="10258608at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056604">
        <property type="entry name" value="GBF1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
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        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF388">
        <property type="entry name" value="GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23325">
        <property type="entry name" value="TPR_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="621"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1537"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1564"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1586"/>
            <end position="1599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1600"/>
            <end position="1610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1610" mass="177800" checksum="CE7AFDBA31595CAA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLF3</accession>
    <name>W6ZLF3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ketoreductase (KR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_98267</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689108.1">
        <property type="nucleotide sequence ID" value="XM_007690918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLF3"/>
    <dbReference type="GeneID" id="19129220"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98267"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF252">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="35753" checksum="8E297DC4C3854E72" modified="2014-04-16" version="1">MGFATTILHSQFFVKPPVPSSDFSGQTIVVTGATSGLGYEAAKHILRLGASKLILAVRNVSKGEQVAKEVSSALSLPLSNVEVWELDLSSFASVKKFGERIKTLDRLDAVIQNAGIMTSKFTPVEECESQIAVNVISPALLGHLVIPKLQESAAKTGSRGRLAFVGSDLQFLAPLKEKSHPGSLLTALNSEEHADMKNRYGVSKLLLMWVVRDLAQRYPLSDQSNVLITCLTPGLCQSDLVRDDESWIAGVIRRFVIGIVARSTEVGSRTLVFGVKPELGEECHGAFLMDCKVCGDLTGNTKSPEMKEAKTKFLGELRARLQEIYPELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLZ1</accession>
    <name>W6ZLZ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Invertebrate defensins family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_80513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682622.1">
        <property type="nucleotide sequence ID" value="XM_007684432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLZ1"/>
    <dbReference type="GeneID" id="19125685"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80513"/>
    <dbReference type="HOGENOM" id="CLU_2514059_0_0_1"/>
    <dbReference type="OrthoDB" id="3680586at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887589" description="Invertebrate defensins family profile domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9120" checksum="88FC82489AC6DEA9" modified="2014-04-16" version="1">MKFTLIAAFATLATVVAGTPTISAFEAREAEAEAVGLVPRACPGARSGCRVDWAKKCEWYCQNRGGFLVMESCYLGFSRCCCRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMM8</accession>
    <name>W6ZMM8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_26905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963996">
        <property type="protein sequence ID" value="EUC44846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688627.1">
        <property type="nucleotide sequence ID" value="XM_007690437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMM8"/>
    <dbReference type="STRING" id="930090.W6ZMM8"/>
    <dbReference type="GeneID" id="19121020"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26905"/>
    <dbReference type="eggNOG" id="KOG2451">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF6">
        <property type="entry name" value="CYTOPLASMIC ALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="3">
        <location>
            <begin position="37"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="489" mass="52711" checksum="7FD4B52BDAC49064" modified="2014-04-16" version="1">MSTNPDSTTPTTPNSFTPLWINNEPIHTTTTFPLTPSSSTTPSHHAYSASPKDATHAATTAWTAFKSWRQTSHTTRRDLLLRVADHYSTHSATLISTQTRETSCTPAWALQNVNLAISYLREIAAQISSVAGVIPPTEKPGTTGFVFKEPIGPVLCIAPWNAALILATRGIASAIAVGCTVVFKASEMCPATHFEITKAFVEAGVPGGVLNQVQCKREDAVAVTEALISHEAIRKVEFIGSAAVGRQIMAVAARYLKPVLMELGGKCPAIVLEDADLGVAARQCALGATMNHGQICFSTERVIVLEGVAKEFQERLVEEMGKVTKEITGAAVSEGIAQHAQDLIRDAEERGDSVVFPRSCDEDKEGGDRPTTVLPPALVLNPLSSSRIFDEETFGPSASLYVVKTDEEAIELANRSAYGLNATVWTRDMARFLKISRELEYGQVHANTISVYTSPTGSQGGVKNSGFGRMNGRWGLEEFVVEKFVTWCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNC8</accession>
    <name>W6ZNC8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_37135</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688388.1">
        <property type="nucleotide sequence ID" value="XM_007690198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNC8"/>
    <dbReference type="STRING" id="930090.W6ZNC8"/>
    <dbReference type="GeneID" id="19123190"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37135"/>
    <dbReference type="eggNOG" id="KOG0616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_3_1"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010619">
        <property type="term" value="P:adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045721">
        <property type="term" value="P:negative regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010515">
        <property type="term" value="P:negative regulation of induction of conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046827">
        <property type="term" value="P:positive regulation of protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="207"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="463"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="54"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC45081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="536" mass="59679" checksum="E22F944D39DD2BF8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNP9</accession>
    <name>W6ZNP9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor U2AF subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">U2 snRNP auxiliary factor large subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_5578</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for the splicing of pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the splicing factor SR family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963989">
        <property type="protein sequence ID" value="EUC45176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688276.1">
        <property type="nucleotide sequence ID" value="XM_007690086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNP9"/>
    <dbReference type="STRING" id="930090.W6ZNP9"/>
    <dbReference type="GeneID" id="19124657"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5578"/>
    <dbReference type="eggNOG" id="KOG0120">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021795_2_0_1"/>
    <dbReference type="OrthoDB" id="10266058at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000097">
        <property type="entry name" value="U2 snRNP auxiliary factor large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006529">
        <property type="entry name" value="U2AF_lg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01642">
        <property type="entry name" value="U2AF_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="254"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="368"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="477"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="95"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="575" mass="63362" checksum="E5C48E2CBCF23DEC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNW5</accession>
    <name>W6ZNW5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nonribosomal peptide synthetase 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Extracellular siderophore synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_2056</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684283.1">
        <property type="nucleotide sequence ID" value="XM_007686093.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZNW5"/>
    <dbReference type="GeneID" id="19119998"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2056"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_60_2_1"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="N-terminal domain of ligase-like"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
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        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF3">
        <property type="entry name" value="SIDEROPHORE SYNTHETASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="778"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="1347"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="1415"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00073487"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00083595"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1939" mass="214492" checksum="A6617379D5C5602E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPU2</accession>
    <name>W6ZPU2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small ribosomal subunit protein uS7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_5166</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC45636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689617.1"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG3291">
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:maturation of SSU-rRNA"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal protein S7 domain"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
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        <property type="entry name" value="PRK04027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal protein S7"/>
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    </dbReference>
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        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="63"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="208" mass="23095" checksum="5CC2C9F9ABFE3416" modified="2014-04-16" version="1">MSDNGEIEVENPTGINILPKDVAEEQGSWSYEEVEVRDISLTDYIQIRSPVYISHSAGRYAVKRFRKAQCPIIERLTNSLMMNGRNNGKKLMAVRIVAHAFEIIHIMTDQNPIQVAVDAIVNCGPREDSTRIGSAGTVRRQAVDVSPLRRVNQGISLLTIGAREASFRNIKSIAECLAEELINAAKGSSNSYAIKKKDELERVAKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ09</accession>
    <name>W6ZQ09_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_5137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687756.1">
        <property type="nucleotide sequence ID" value="XM_007689566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ09"/>
    <dbReference type="STRING" id="930090.W6ZQ09"/>
    <dbReference type="GeneID" id="19124506"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5137"/>
    <dbReference type="eggNOG" id="ENOG502RWEH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011082_1_0_1"/>
    <dbReference type="OrthoDB" id="2624308at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="787" mass="88584" checksum="44349E0CB6AB9514" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQR5</accession>
    <name>W6ZQR5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_32850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683650.1">
        <property type="nucleotide sequence ID" value="XM_007685460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQR5"/>
    <dbReference type="STRING" id="930090.W6ZQR5"/>
    <dbReference type="GeneID" id="19122190"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32850"/>
    <dbReference type="eggNOG" id="ENOG502RXVZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049761_0_1_1"/>
    <dbReference type="OrthoDB" id="2367685at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32347" checksum="8CEFFD23789E9917" modified="2014-04-16" version="1">MATSQHPNEPPPSYEAAIFDADPSPGIRRVSTDGPAARTERNGIPPNRRRSMEDLMRELPPGWIRSFDEQTQHQFFVDTRANPPRSIWTHPYDDEEYLSTLSPEERKKHTRMHKTMTMEDLAAEDSDTEDHLPPQPTSKGKGAAAPGEPTGIHKFSRKLKDKITGQTHEEREKARQRRAEEERQAYLQHMRTRQAIIRAMETGEPQLIGKDRQGRDVYIEPPQGRFAPSGAYGYNPYGPRQYYNPGVRYMRPATPYGRPYGYGYGGGAGLPLAAGLLGGTLLSTALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRI6</accession>
    <name>W6ZRI6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_93151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963968">
        <property type="protein sequence ID" value="EUC46321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687181.1">
        <property type="nucleotide sequence ID" value="XM_007688991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRI6"/>
    <dbReference type="STRING" id="930090.W6ZRI6"/>
    <dbReference type="GeneID" id="19128212"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93151"/>
    <dbReference type="eggNOG" id="KOG1549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_3_0_1"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="77"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="481" mass="53527" checksum="37A7F2B83D3ACA94" modified="2014-04-16" version="1">MTSNAKYGVPDIKTKDGIAFGKELRDEAFLFDRGFLNLNHGSFGTYPRPVQDKFRAFQDASEARPDQFIVYDYPRYLDEAREAMGKLLNTPSSTLVFVPNATTGVNTVLRNLTFTPGDHILIFSTIYGACEKTVAYVTETTPAQAVKVEYTFPVEDDWLVTEYEKKVKEVEAKGGKVKIAIFDTVVSMPGVRLPFERLTAKSKELGVLSCIDGAHGVGHVEIDLGTLDPDFFVSNCHKWLHVPRGCAIFHVAHRNQAMIRSTLPTSHGFLPKGSKFVSPFPKPSFTKPGAEQNTSEQSASLGNKSAFVNDEKPAFIANFEYVGTIDSSPYLCIPKALEWRETLGGEAVIRKYCHTLAQAAGQHVASVLGTEVLENSTGTMGQCCLSNVRLPISLDKVFHTAANSGVDKEDVGVKVRDWMKKLSSEEYDTFIMVYWYAGSWWSRLSAQVYLEMKDFEWAAKTLKEMCERVEKGEWAGIKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSX8</accession>
    <name>W6ZSX8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_21935</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682829.1">
        <property type="nucleotide sequence ID" value="XM_007684639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSX8"/>
    <dbReference type="STRING" id="930090.W6ZSX8"/>
    <dbReference type="GeneID" id="19120141"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21935"/>
    <dbReference type="eggNOG" id="ENOG502QW0K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007003_6_0_1"/>
    <dbReference type="OrthoDB" id="2162761at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="42"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="138"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="655"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="711"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="659"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="711"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="740"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="905" mass="99762" checksum="2D64ADF5CE739B5A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTD9</accession>
    <name>W6ZTD9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CASTOR ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_35422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC46986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686480.1">
        <property type="nucleotide sequence ID" value="XM_007688290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTD9"/>
    <dbReference type="GeneID" id="19122781"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35422"/>
    <dbReference type="eggNOG" id="ENOG502RXBJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036623_1_0_1"/>
    <dbReference type="OrthoDB" id="58529at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051719">
        <property type="entry name" value="CASTOR_mTORC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131:SF6">
        <property type="entry name" value="CASTOR ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASTOR ACT" evidence="1">
        <location>
            <begin position="109"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="391" mass="42953" checksum="BBA0E971F6367C4B" modified="2014-04-16" version="1">MESSLILLSANIRILDTELALIHIPLRLYRTFLQSILQLVLPNATRDGFDNGSGAVQPLNGWPCEHPFVNISITPVECSIVCSRDLANELFVPVLSLLDAESRESVNITQDDFVVMQVDGEGLDAGQRVLELTSPLALAGIPIFFITTYFSDYILVPLRHRSQVVQALEERGFQFEKDTSSYVNSFQPGRKHSAASLEVQPPRSPPPTTISELQTKTFATLKRRNIVPTVDSSIRLVQCAGRRDGMNQARNRNSRTTVADDALHLGLVKCLITQPYPKFLSLTLTDTESAALLLDHTLLPHFVQDTLLGSRDEFLTPITLDLRELSMESTGIVCGVAGRLVGETTRQLQDPVEMSYLSTARAGTVMVAEEELQRALGALRGAENGVAAANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTN3</accession>
    <name>W6ZTN3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7721 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_80694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682587.1">
        <property type="nucleotide sequence ID" value="XM_007684397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTN3"/>
    <dbReference type="STRING" id="930090.W6ZTN3"/>
    <dbReference type="GeneID" id="19125710"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80694"/>
    <dbReference type="eggNOG" id="ENOG502S2II">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063290_2_2_1"/>
    <dbReference type="OrthoDB" id="2290255at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056138">
        <property type="entry name" value="DUF7721"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477:SF1">
        <property type="entry name" value="BETA-FLANKING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24845">
        <property type="entry name" value="DUF7721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7721" evidence="2">
        <location>
            <begin position="2"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="172" mass="17398" checksum="832F26ACA6AA19B7" modified="2014-04-16" version="1" fragment="single">DDFSGAAQHAASEYGSGGDSSLFTSALGMLAGNKNSYQNESVDEDDAVKQHEKFYGNGGSGGGQASSNNVGAAAAMQALKMFNNSSNEDAKGGQNKFIGMAMGQAAQLFDKQQSQGNTDASATKQDAIVQAGKFALQFYMKSQMGGGSGGSGGGSDSALGGVLNMASKFMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUK7</accession>
    <name>W6ZUK7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_79718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682174.1">
        <property type="nucleotide sequence ID" value="XM_007683984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUK7"/>
    <dbReference type="GeneID" id="19125531"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79718"/>
    <dbReference type="eggNOG" id="ENOG502S2RN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090569_0_0_1"/>
    <dbReference type="OrthoDB" id="1161823at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02223">
        <property type="entry name" value="cupin_Bh2720-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052538">
        <property type="entry name" value="Flavonoid_dioxygenase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43346">
        <property type="entry name" value="LIGAND BINDING DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14370)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43346:SF1">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="2">
        <location>
            <begin position="57"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="175" mass="19221" checksum="D9BAC7D043E25AC7" modified="2014-04-16" version="1">MEGYKKVGNREDAPPKHEMVYFPGLMSEKRSFGDFRTVLHTGLYDADENNTGQIVAMEVPVNGEIGDEVHLVDQILLFTSGRGLATVAGKEQEVTAGDVVVVPAGMQHQFVTKGEQPLELITVYSPAEHLPSSVHKNKEEGDKAEEEGVDEAPAWALRGKEENEKEGLVRESGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZV14</accession>
    <name>W6ZV14_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_34887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685849.1">
        <property type="nucleotide sequence ID" value="XM_007687659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZV14"/>
    <dbReference type="GeneID" id="19122662"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34887"/>
    <dbReference type="HOGENOM" id="CLU_1053713_0_0_1"/>
    <dbReference type="OrthoDB" id="3673901at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790:SF4">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="41"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="264" mass="30608" checksum="D4F22D4823BCCA4E" modified="2014-04-16" version="1">MDPLNRLKRRLSKRSFPRAYEHPTHPYEDDESDTATMVEIEQDSSFLRLPANVRELIYGHVLGGTQIRVCDTRNCTRRHKCRSRGRKLHFATYFHLRRRHLALLTTCRQIHAEARLLPFALNEFHGYHWDMQLAVYYRLTDAQVGAMTNLRVYFECNDVIYYPALGRRSPSVNLGKDALATLRVIGHLRGLRKLTVEWVGPHDWEHDWAMVEGRMAYLIEEELEQIRGSCDIKVVVVGCDYVEDLDTGPVPVVGDMPKLVSFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWZ8</accession>
    <name>W6ZWZ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_2797</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685112.1">
        <property type="nucleotide sequence ID" value="XM_007686922.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZWZ8"/>
    <dbReference type="GeneID" id="19121220"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2797"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006477_0_0_1"/>
    <dbReference type="OrthoDB" id="3918771at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="49"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="740"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="773"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1187"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1414" mass="159784" checksum="E7C0E1DC945F4C2C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYF4</accession>
    <name>W6ZYF4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_86823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684892.1">
        <property type="nucleotide sequence ID" value="XM_007686702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYF4"/>
    <dbReference type="GeneID" id="19126942"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86823"/>
    <dbReference type="eggNOG" id="ENOG502S8WA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_966396_0_0_1"/>
    <dbReference type="OrthoDB" id="4941332at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="288" mass="32569" checksum="DF8D964870FBF2EB" modified="2014-04-16" version="1">MSNTAEIWSALGLPARAAARVLLAPRYLINGFSRLREWNDNAWARTRYGPSYRYRLWLLFDAQDLEVLEHIINEGTDKEVLELREAKLEQFRLVALVGALLATLALQAMSLPQLSDTTFIVRSCFTQGTMLSLLATFFTCIQQRELGFVRTASALRIWLSNGVQYRDSREHLVWQSSLTSLTLMEAPYELISLAVTNFVCGMSAYMWSAWKDNLPVQKEGDVLRRMAVLVYFAVGTGFAFTLFPVLLGAKDDEGKFGCTEMDSLIEGQGQGQGMWDEGRVEVQQKRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYM8</accession>
    <name>W6ZYM8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_23548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYM8"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_23548"/>
    <dbReference type="HOGENOM" id="CLU_2120672_0_0_1"/>
    <dbReference type="OrthoDB" id="10353258at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887777" evidence="1">
        <location>
            <begin position="26"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="114" mass="12483" checksum="FCC1BAB91047F7C4" modified="2014-04-16" version="1">MPLPLPPGPWAFSALHLCLVATLPACPQHCHWPAATCQSRCIQCECLLPAPRTCWLLLSAAVIFARGFGPRRALSSQTPNQARVLDTGWWFKEAYQVAITSQMLWGSGLNPLGL</sequence>
</entry>
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    <accession>W6ZYT8</accession>
    <name>W6ZYT8_COCMI</name>
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        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_23446</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat mio family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC48881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686421.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZYT8"/>
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    <dbReference type="eggNOG" id="KOG1008">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="341486at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16691">
        <property type="entry name" value="mRING-H2-C3H3C2_Mio"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037593">
        <property type="entry name" value="MIOS/Sea4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049092">
        <property type="entry name" value="MIOS_a-sol"/>
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    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031488">
        <property type="entry name" value="Zn_ribbon_mio"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453:SF9">
        <property type="entry name" value="GATOR COMPLEX PROTEIN MIOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453">
        <property type="entry name" value="WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21719">
        <property type="entry name" value="MIOS_a-sol"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="zinc_ribbon_16"/>
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    </dbReference>
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        <property type="entry name" value="WD40"/>
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    </dbReference>
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        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
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        <location>
            <begin position="462"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="GATOR2 complex protein MIO zinc-ribbon like" evidence="5">
        <location>
            <begin position="907"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="847"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="851"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="871"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="881"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17034"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF21719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="987" mass="109071" checksum="C666225E133327DE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYU7</accession>
    <name>W6ZYU7_COCMI</name>
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        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_2344</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 12">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZYU7"/>
    <dbReference type="GeneID" id="19120432"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2344"/>
    <dbReference type="eggNOG" id="KOG2906">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093932_3_0_1"/>
    <dbReference type="OrthoDB" id="282152at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
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        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034014">
        <property type="entry name" value="Zn_ribbon_RPC11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF12">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="13">
        <location>
            <begin position="75"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="10">
        <location>
            <begin position="5"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC48891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="118" mass="13963" checksum="274B7E3EC7FCD991" modified="2014-04-16" version="1">MLLFCPTCSNMLRVSAVPPGDPTTEDFVGQNRFECLTCPYHFVINKRYYERKYMKKKEVEDILGGKGAWDNVDKTEVQCPNEKCRNHEAYWYQLQIRSADEPMTAFYKCTQCAKEWRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZV2</accession>
    <name>W6ZZV2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_84983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684224.1">
        <property type="nucleotide sequence ID" value="XM_007686034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZV2"/>
    <dbReference type="STRING" id="930090.W6ZZV2"/>
    <dbReference type="GeneID" id="19126576"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84983"/>
    <dbReference type="eggNOG" id="KOG0835">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022000_5_0_1"/>
    <dbReference type="OrthoDB" id="10264655at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000126">
        <property type="entry name" value="Cyclin domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32905" checksum="9C7E46AE81EED04A" modified="2014-04-16" version="1">MQPSPLTNALATVAQLETSGSQLDGIPPDLEDSIRFAGARLTQAAGILLRLPQEVIAQAIVVFMRFWLGPEGGSLAEFGAEQVSAASLYLTTKLSAYPKSARSIINVYAYLDSLPTTFFGVDQLHQKQDPREYFVTEGTYERRRATLFSTEQRILRTLGFNVQIQLPYTLCITYLQALDIFVHPRASELAKRAIAYLNTALLSPQCLYLTHQPPTLATAAIYLAARETGIKMPECEWWEVFDTDREVLGFLCVGMLSLEGFAQEEKKKWEGTKVPMNVEDLEREMERRQEVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3P1</accession>
    <name>W7A3P1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2293 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_81348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682930.1">
        <property type="nucleotide sequence ID" value="XM_007684740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3P1"/>
    <dbReference type="GeneID" id="19125852"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81348"/>
    <dbReference type="eggNOG" id="ENOG502SQ7Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_471838_0_0_1"/>
    <dbReference type="OrthoDB" id="5288828at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018744">
        <property type="entry name" value="DUF2293"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113:SF1">
        <property type="entry name" value="DUF2293 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10056">
        <property type="entry name" value="DUF2293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2293" evidence="2">
        <location>
            <begin position="178"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="687" mass="78753" checksum="22388B780B93D444" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4M8</accession>
    <name>W7A4M8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Smr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_31671</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the USE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682363.1">
        <property type="nucleotide sequence ID" value="XM_007684173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A4M8"/>
    <dbReference type="STRING" id="930090.W7A4M8"/>
    <dbReference type="GeneID" id="19121927"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31671"/>
    <dbReference type="eggNOG" id="KOG2401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_438161_0_0_1"/>
    <dbReference type="OrthoDB" id="3231855at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013899">
        <property type="entry name" value="DUF1771"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053020">
        <property type="entry name" value="Smr_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019150">
        <property type="entry name" value="Vesicle_transport_protein_Use1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47417">
        <property type="entry name" value="SMR DOMAIN-CONTAINING PROTEIN YPL199C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47417:SF1">
        <property type="entry name" value="SMR DOMAIN-CONTAINING PROTEIN YPL199C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08590">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09753">
        <property type="entry name" value="Use1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01162">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Smr" evidence="13">
        <location>
            <begin position="385"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="99"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="158"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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            <begin position="460"/>
            <end position="510"/>
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    </feature>
    <feature type="coiled-coil region" evidence="10">
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            <begin position="305"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
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        <location>
            <begin position="172"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
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            <begin position="474"/>
            <end position="510"/>
        </location>
    </feature>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC51116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="534" mass="59479" checksum="F99725C4F424868E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJU2</accession>
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        <recommendedName>
            <fullName evidence="14">Polyadenylate-binding protein</fullName>
            <shortName evidence="14">PABP</shortName>
        </recommendedName>
    </protein>
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        <name evidence="18" type="ORF">COCMIDRAFT_110979</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="12">Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN.</text>
    </comment>
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        <subcellularLocation>
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        <subcellularLocation>
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        <text evidence="3 14">Belongs to the polyadenylate-binding protein type-1 family.</text>
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        <property type="project" value="UniProtKB-ARBA"/>
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    </dbReference>
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        <property type="entry name" value="RNA BINDING PROTEIN"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RNA-binding domain, RBD"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 13 14" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="48"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="16">
        <location>
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            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="16">
        <location>
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            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="16">
        <location>
            <begin position="332"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="17">
        <location>
            <begin position="652"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="363"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
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            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
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            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="728"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="523"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
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            <end position="652"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC39642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="749" mass="81297" checksum="38F62AC2F9AC09DC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJV6</accession>
    <name>W6YJV6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110927</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964288">
        <property type="protein sequence ID" value="EUC39657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693824.1">
        <property type="nucleotide sequence ID" value="XM_007695634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YJV6"/>
    <dbReference type="STRING" id="930090.W6YJV6"/>
    <dbReference type="GeneID" id="19119689"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110927"/>
    <dbReference type="HOGENOM" id="CLU_204926_0_0_1"/>
    <dbReference type="OrthoDB" id="3942798at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="8030" checksum="41E85636732F2C29" modified="2014-04-16" version="1" fragment="single">ISRGTKTDILSSIYSLKIGHGYFNAYLKRFKRRERELCRCGRLQTAEHLLLYCGFYSAERNQLKKTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YKT1</accession>
    <name>W6YKT1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cupin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_110508</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="KI964245">
        <property type="protein sequence ID" value="EUC39812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693668.1">
        <property type="nucleotide sequence ID" value="XM_007695478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YKT1"/>
    <dbReference type="GeneID" id="19119610"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110508"/>
    <dbReference type="eggNOG" id="ENOG502QQ0P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030515_2_0_1"/>
    <dbReference type="OrthoDB" id="10263073at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033609">
        <property type="term" value="P:oxalate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20305">
        <property type="entry name" value="cupin_OxDC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20304">
        <property type="entry name" value="cupin_OxDC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017774">
        <property type="entry name" value="Bicupin_oxalate_deCO2ase/Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051610">
        <property type="entry name" value="GPI/OXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03404">
        <property type="entry name" value="bicupin_oxalic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848">
        <property type="entry name" value="OXALATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848:SF9">
        <property type="entry name" value="SLL1358 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886487" description="Cupin type-1 domain-containing protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="146"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="327"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC39812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="496" mass="53623" checksum="F19027E0A247049D" modified="2014-04-16" version="1">MRYSFVHVLSSLAGSALAFPAPQASAIPDPVDPSAVASDQVLPKGASGSLRGSEALIGFAAANPISTKSTVIPPDEFELGTGQSADPDEGLYIDLTNVKNPQPIRGGTTGPTDPGPRTDAYDALNSDIFAPPTTDAGDVGQAKWPFGLSHNRHGLAGAGWARNQNVNQLPIATAMAGVNMRLSPNAYRELHWHKQGEWALMLNGSVRIQSMNEAGQTFVDDVQEGDVWFFPPGIPHSIQAFDTGCEFLLVFDSGDFSEDNTFLLSELMERNPKEVLAKNFRTTTKTFDSLPDGQLWIFPGTPAPKNISEQNVTGPAGLIPKQTQYTYHFSQQQPLKVPGGSIKILDPTTFPVASSFSTALITVEPGAMREMHWHTTSDEWTYFLQGSARLTVYQAPGSSRTFDFTAGDVGYVPVPNAHYLENTGNETLVFLEVLQAKEYSDISVNQWLGLTPKQIVKDHLKVSDGFLATLRKDKPIIIQGNPDLTTTDFTPTAGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLL5</accession>
    <name>W6YLL5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL22</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_41515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964198">
        <property type="protein sequence ID" value="EUC40097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693375.1">
        <property type="nucleotide sequence ID" value="XM_007695185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLL5"/>
    <dbReference type="STRING" id="930090.W6YLL5"/>
    <dbReference type="GeneID" id="19124073"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41515"/>
    <dbReference type="eggNOG" id="KOG3353">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083987_0_0_1"/>
    <dbReference type="OrthoDB" id="10254664at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.10:FF:000010">
        <property type="entry name" value="60S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_uL22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005721">
        <property type="entry name" value="Ribosomal_uL22_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01038">
        <property type="entry name" value="uL22_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593:SF10">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="186" mass="20680" checksum="EAD2655344EE08B3" modified="2014-04-16" version="1">MVRYGATSIDGAKSARARGSYLRVSFKNTRETAQAVNGWKLERALTYLGNVLEHKEAVPMRRYAGSTGRTAQGKAFGVSKARWPVKSAEILIGLLKNAEANADTKGLDTSNLIIKHIQVNQAPKQRRRTYRAHGRINPYMSNPSHIELILTEGAEVVQKGPQTLERRLNSRQRGRAVRKAITASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNE8</accession>
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            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
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    </dbReference>
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        <property type="entry name" value="Bestrophin_2"/>
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    </dbReference>
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            <end position="85"/>
        </location>
    </feature>
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            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="319"/>
        </location>
    </feature>
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            <end position="346"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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            <end position="461"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="477" mass="53035" checksum="8A6D560FC1CD24EE" modified="2014-04-16" version="1">MTTEKAQSTASVSNGTNGNSSKRPPLKKQDSDKDFDDYFIGPRDLDHHSKWPVFLRVHGSVTPEMVLPLLFVAGWASMITLISKFVHDLSVNQLLLTVLGFVVGLALSFRSSTAYERYNDGRKYWAQLTFASQNLARLIWIHVDERHDQDPELGKQDLLAKINCLNLIAAYSVALKHKLRFEPYVHYDDLQHLAGHLDTFAREADQPDTNKKPNVFKTAGKFLGLPMAESNPRKLLKRSRVPLGNLPLEILNYLSIYMKSIYDNGTFKVSIYQTQSLNAITTFNDILAGTERILSTPLPIAYSIAISQITWVYILLLPFQLYKLLGYITIPASVFAAYIILGIALIGREIENPFGDDVNDLPLDAFCLQIRKDIDIIMSKPASSIEEVVMHPENQLLYPLSKLGSAGWAAKSVEEIRDALASKPGLHFPLVEHDEHPRPSQSGGAGLRRRTTNEHRAEEGAAGHSVSSSNAGGDAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ06</accession>
    <name>W6YQ06_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964315">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_111113"/>
    <dbReference type="eggNOG" id="KOG0254">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF109">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
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    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-0813">Transport</keyword>
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            <end position="55"/>
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    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="380"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC39598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="554" mass="59099" checksum="A5E6F94383551ABC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQI7</accession>
    <name>W6YQI7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40177</name>
    </gene>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964091">
        <property type="protein sequence ID" value="EUC41677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693613.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6YQI7"/>
    <dbReference type="GeneID" id="19123830"/>
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    <dbReference type="OrthoDB" id="67965at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF15">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="27659" checksum="E3E9338985B6F499" modified="2014-04-16" version="1">MTLDLNVDAYTGQQQRDKTTGVKKCDRQALETLRSEASKKKDLVPRGDYRPSPAGKLTFFVLRSLEPAPQCSILAHGFGTSVLTSRLINGLGLSPYRLVLLTMSVGSVVKQNIWVTILSRGSMTVGVAVAIAMLNAASNSLSTYAFPALPIGGTLHVVGILTELITEIQRERFKADPNNKGKVCTGGLWGLARHINYGGYTMWRAGYAMAGGGYGLGALRAIPVLSEYCEKWYGAQWEAYRQKTPYELIPYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQX5</accession>
    <name>W6YQX5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_31045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Vacuole membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATG22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI964224">
        <property type="protein sequence ID" value="EUC39913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693574.1">
        <property type="nucleotide sequence ID" value="XM_007695384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQX5"/>
    <dbReference type="STRING" id="930090.W6YQX5"/>
    <dbReference type="GeneID" id="19121793"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31045"/>
    <dbReference type="eggNOG" id="ENOG502QTJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080477_0_0_1"/>
    <dbReference type="OrthoDB" id="42657at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF5">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC39913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="257" mass="28024" checksum="AC66A35AD6775ECD" modified="2014-04-16" version="1" fragment="single">MATPDASFAPFSSLNKDSTAVGNNGLTLSNFAPTAFQNLVYAASRGAETLHFLGKTLTANSIVLLCNGISFAIQIIIFLLLGSFADFGTWRPNILIILSIVAFGIGFGWLGVHNGEDWKIGPGLYIVGLIVYQTTITFWTAAFLGLARNTEAVRTKAGQLTEGTITRDEYEFVDMMKRNEISNTAFYVQSIIEIFILAIIVGIMFSLHINDSAENNNWGLSVLIFFATGVWVICAIPGFVLEKRRPGQDPESNIVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSC2</accession>
    <name>W6YSC2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate esterase family 3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_103730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964064">
        <property type="protein sequence ID" value="EUC42342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691129.1">
        <property type="nucleotide sequence ID" value="XM_007692939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSC2"/>
    <dbReference type="STRING" id="930090.W6YSC2"/>
    <dbReference type="GeneID" id="19118365"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103730"/>
    <dbReference type="eggNOG" id="ENOG502SIJX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044083_3_1_1"/>
    <dbReference type="OrthoDB" id="3915838at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF5">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886050" evidence="1">
        <location>
            <begin position="26"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="45"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="244" mass="25791" checksum="361AF3D86B633288" modified="2014-04-16" version="1">MLSKIMKQLALPLAILSFFLSFASALPTDASLESRQTKSLRILPLGDSITWGWINGGGSNGYRERLLSDLQSGGYTVDFVGTQKSGTMADKDNQGFPGYTINQIRGVAGGGLNLRPNVVLIHAGTNDLNRGNPSSEPDADAPRRLGLLIDDVLKVVPNAVVIVAKIIPSKRASLTNTIRTFNNALPAIVSARASKGSKVSLVDMGVLNPSSELSDDLHPNVAGYNRMGDIWNAGIRAVAGSIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSY2</accession>
    <name>W6YSY2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964146">
        <property type="protein sequence ID" value="EUC40680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692792.1">
        <property type="nucleotide sequence ID" value="XM_007694602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSY2"/>
    <dbReference type="GeneID" id="19119191"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108150"/>
    <dbReference type="eggNOG" id="ENOG502QQSB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031217_0_0_1"/>
    <dbReference type="OrthoDB" id="2099887at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889197" evidence="1">
        <location>
            <begin position="17"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="500" mass="55567" checksum="5B7BFEC475860DBB" modified="2014-04-16" version="1">MKWATITAALLPLASASGFTRQEYASGEVMELMMNGKETAWAKQRAAGKFDSARWNGFEKKRTDKSVIKCKFGRVEAVKDDPDQTYRCNNIDLYDFKTHAELGDPIGDGSGSWGWTHRGREFIAIGQTYGASFSEVTREGKLEYLGRLPAQNDSVIWREIKVLGDSLIVGSEGIGHHVQIFDLKKLLKLSPKNPYTFDKVKDVALVDINQGIKGRTHTVVANEEKNYAVACGAGGRPGRNDTCAGGPMFINMDDPTKPYVEGCYSGDGYVHDSQCIVYRGPDRRYYGRDICFLYAEDTLTIIDATNKKGFGTAGKLISRTPYVGASYTHQGWVIDPYWQTHLVLDDELDEGQIDPNRTAVDSPARDGFAVTYILDIQNLEKPFVSGLYKTTVRSVDHNQYVYDGLSYQSNYQAGLRILDVSSIPKYPDGSKVKEIAYFDVYPGDDAKPGGGDALWDAGTWSAYTFDSGYVVINTIDRGVFVVKQADVKGRKKGKGQFWKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU35</accession>
    <name>W6YU35_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_107237</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964123">
        <property type="protein sequence ID" value="EUC41038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692441.1">
        <property type="nucleotide sequence ID" value="XM_007694251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU35"/>
    <dbReference type="STRING" id="930090.W6YU35"/>
    <dbReference type="GeneID" id="19119007"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107237"/>
    <dbReference type="eggNOG" id="ENOG502SC34">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059403_0_0_1"/>
    <dbReference type="OrthoDB" id="427960at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="261" mass="27784" checksum="87F7163C63E597A1" modified="2014-04-16" version="1">MQRAAAKSSPSSPATSNGPPAKKARLSHGASAVGTSDQEIIQSGLDAEEAKRQAALDKAAQHAGETKWVLSFQDPLKGKRQDAMQVRHAGYAEIDAQDDSEEEEEEEEEEEEDTRPVRMQFGGGVKKVDTSVPMVKTEDSESDSESSSDDYDSDDAAADLIRQTKREIASEKRESKKKRASMGNSTPNGTSTRQNENRSLNGLTSISGGRRSGGGGISGGSSRMDNVDCYKCGEKGHIAANCSNPSAPRGSAGRGYGKGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUZ4</accession>
    <name>W6YUZ4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_29839</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964106">
        <property type="protein sequence ID" value="EUC41370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692104.1">
        <property type="nucleotide sequence ID" value="XM_007693914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUZ4"/>
    <dbReference type="GeneID" id="19121577"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29839"/>
    <dbReference type="HOGENOM" id="CLU_1272081_0_0_1"/>
    <dbReference type="OrthoDB" id="5418336at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="28"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="217" mass="24773" checksum="F1176F42C9C181EC" modified="2014-04-16" version="1">MRYPFPSLRSTVWSSSLVKVLELLRLKQGKRSLLWIKGGPGKGKTMLSIFLAEDLELLLSNEQIKQVAYYFCIRNKRPEIAKHAFPYLELPERRADTLCSLASLWIILQKIIADAALGHLFCIVDGFDECDEDTQRFLIPRFVDQLGSQTSPNRPENLPKFLIVSREIERLECCNKGDLDEDHVSNGGGGDVELLIGEKVDELFHRKRLDNAFRPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVS3</accession>
    <name>W6YVS3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Reticulon domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_100706</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964027">
        <property type="protein sequence ID" value="EUC43517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689995.1">
        <property type="nucleotide sequence ID" value="XM_007691805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVS3"/>
    <dbReference type="STRING" id="930090.W6YVS3"/>
    <dbReference type="GeneID" id="19117726"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100706"/>
    <dbReference type="eggNOG" id="ENOG502SHFU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041562_0_0_1"/>
    <dbReference type="OrthoDB" id="567788at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003388">
        <property type="entry name" value="Reticulon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02453">
        <property type="entry name" value="Reticulon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Reticulon" evidence="7">
        <location>
            <begin position="62"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="268"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="268"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="434" mass="45781" checksum="E3E89C3BDF2A3979" modified="2014-04-16" version="1">MSMQNVIVVPVAGEGARQPGQDTTEIASTIQHALEESAHPKQPQPGPLKQIIAHQESLYQYINWDDPTRTLGSYIGVLSLLFGAHYLPLTQMALKGGVTALGLVSVTESASRMLGNRSLSAQLRPKEYKTFPEPTLNATLKDIHDFVQYAAVQAQRIVFGQDLQKTFASFLGLTALYWLIKVVSPFWLAVLAVTSVYAAPLITSPRGREIAREAGTNAQELAAAATHNGRMLAHDASANAQKLANTETGRAATNSISSGAQEVANQGNALAQKGKQTASDLSSQAKSTASDLSSKAQGTASSVSNSATGSLKHAQKASSNAAQRTVDTATSAANHAANHAASTANQAANHTKEYTNAHGPTVYSSSPTSTSHANDRAQVRGPEGDRATPRGVVVAQSGYTGAKVTEAQEPAVMYTTARDEALERRVLERSRGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVT0</accession>
    <name>W6YVT0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase family 31 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_10302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964301">
        <property type="protein sequence ID" value="EUC39624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693860.1">
        <property type="nucleotide sequence ID" value="XM_007695670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVT0"/>
    <dbReference type="STRING" id="930090.W6YVT0"/>
    <dbReference type="GeneID" id="19118206"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10302"/>
    <dbReference type="eggNOG" id="KOG2246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022549_1_1_1"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="472" mass="54598" checksum="CB9225F08C93D1A7" modified="2014-04-16" version="1">MSAFRKHMPRTTRLLVTVFFLYIFVWVKGWPRIYDEEELPAVQRPQQQGAPVGPYQVERDQLVVSVTTTAINVNSKVAPLILNTANEDHGMLLLFSDLQAQIGAWPIFDVVWRLTADVVLHIDELKRYRTQLDFARRSIPLQNLVKADPEEEKKDMLVLDKYKILQTMNAAWEYRPGRSWYIFVNDETYVNRPNLIDWLGQHNPDAKHYFANPPIPAETLVPDPFAPSGTSFIVSRKAMMELFVDRKDYIKKWAKHIPEYTSAYHLVTSVLQEELNMSAVPVWPGITGYDPSTAPFHPSLWCEQVMVMHHVTPRMGGDLAKLEREQPAHQPMRFADLWNHFFTPEDLNSTRSNWDNLSSEASNGRWNILFENDEGAKDRAKSGEESPEACRQSCEASTYCVQWSYSSIPQTNWNDNPETKCHLSSSIRFGAYVKPKEVSGTDGKQTLTWKSGWKKARFHNWARRQRCNQHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX30</accession>
    <name>W6YX30_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964200">
        <property type="protein sequence ID" value="EUC40079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693396.1">
        <property type="nucleotide sequence ID" value="XM_007695206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX30"/>
    <dbReference type="STRING" id="930090.W6YX30"/>
    <dbReference type="GeneID" id="19121769"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30916"/>
    <dbReference type="eggNOG" id="KOG2983">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034402_2_0_1"/>
    <dbReference type="OrthoDB" id="360540at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905143">
        <property type="term" value="P:eukaryotic translation initiation factor 2 complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="395" mass="45365" checksum="3B5B7CF359782A87" modified="2014-04-16" version="1">MGYTELPFPPVTKQHILNCSYHSWHPKYRAVTPKARLIPLPSAFLEYLRSDGIVLPPEESDDPSWSDNDSGIFSGADNNDDDAEESIDPSAEWRDTHEAIERTIEELGGKVAPKLNWSAPKDATWIAATNSMECRTPNDIYLLLKSSDFVTHDLAHAFDDTADQSITPDPAIPYHLVLRKWITLNPSVEFRCFVRNRRLIALCQRDLNHFDFLFNMQDKLRDLIQDFFDAKLRDTFPDPNFTFDVYVPPPHDKVWVVDFNPWAVRTDPLVFSWMELLTMDVPEAALAEETTVRLKIAQPEAKSESVPVPNDVLEEDDLSDDNDIEEVWQPEFRLVRRDDPEAYGFTTPQYSAHKLPKDVVDASRGGEGQLREFAMQWEQAQKLAEQQRAEDSEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXK2</accession>
    <name>W6YXK2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_39664</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964067">
        <property type="protein sequence ID" value="EUC42280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691215.1">
        <property type="nucleotide sequence ID" value="XM_007693025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXK2"/>
    <dbReference type="GeneID" id="19123726"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39664"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_0_1"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="442"/>
        </location>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="56337" checksum="27570EEC95803D3F" modified="2014-04-16" version="1">MDAELTAQLVRVLQTTGIAAVVLAAWIFVPKLQHRYYMSKLPKVTAGAAYATTAGKIYKEGYKQYKDQAYTLVNDQGNENVIVPMRFLPELRNLGDDVLSFSKGITDEMEIRYTKLVAESHTVTDTVKTKLTSSLPRLHTSIADDVKLAFQIFLPPCDDWTEVNINEKLVPIIAKVSGSVFVGPEISSHPDYLDAACMYPVDLFNVVTAVKKINPWLKPFLAPRTPEVLTLRKREQQAKNVLRPIIEQRIAAKAKDPEWKEPEDVLQWIINRSIGKISIDEIVGGQLTLIFAAIHTTSTTVTNTMFTLVSKPEYIKPLQEEIRQAIAEEGGVTYRAVQKMEKLDSFMKEVLRFHGPSLTGMLRRVLKGVTLSNGQYIPPGVMIEVPSQAIYHDDKFYPDPEVFDGFRFYKARSTGKAADIARNQFITTNEENLTFGHGRHACPGRFFAALEIKMIMARFLLDYDIKMPNGQTERHPQIEMGRISIPYPAGQLLFKKRAAA</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="139" mass="14974" checksum="EC38ED2F168F3BB3" modified="2014-04-16" version="1">MTCMVDGCWGSRDGSGCMGSTKHVSMFGSVLLSTRLSTGTYSLVDTQTATEKVPVDLVKTAAHWLQAASTRGVQRARASMLGASSAAGRETLNQTGYMYYVLRMRSPPEATGDMHMCVTVRPGYRRQLQEFQAPASAAL</sequence>
</entry>
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    <accession>W6YYP3</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="121"/>
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        </location>
    </feature>
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    </evidence>
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</entry>
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    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="KI964046">
        <property type="protein sequence ID" value="EUC42893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690611.1">
        <property type="nucleotide sequence ID" value="XM_007692421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ80"/>
    <dbReference type="STRING" id="930090.W6YZ80"/>
    <dbReference type="GeneID" id="19118054"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102295"/>
    <dbReference type="eggNOG" id="KOG2413">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011781_2_3_1"/>
    <dbReference type="OrthoDB" id="9995434at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000010">
        <property type="entry name" value="Probable Xaa-Pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000003">
        <property type="entry name" value="Xaa-pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000007">
        <property type="entry name" value="Xaa-Pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase N-terminal" evidence="17">
        <location>
            <begin position="49"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="16">
        <location>
            <begin position="362"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24 C-terminal" evidence="18">
        <location>
            <begin position="592"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC42893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="654" mass="73007" checksum="D64B7B1AD6854D13" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZL2</accession>
    <name>W6YZL2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_7494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964042">
        <property type="protein sequence ID" value="EUC43023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690453.1">
        <property type="nucleotide sequence ID" value="XM_007692263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZL2"/>
    <dbReference type="GeneID" id="19125302"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7494"/>
    <dbReference type="eggNOG" id="ENOG502T77U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_765054_0_0_1"/>
    <dbReference type="OrthoDB" id="3794120at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="211"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="392" mass="44067" checksum="F66AA69BF37FA63A" modified="2014-04-16" version="1">MTTSYTTPPASSERRASIGETSNPIVISSPSPQLKPFKPHQMLMQTPVEIECGPDLSIKLTIHEELLCCHSKLLEERFTKAKNLRKQFEQTDHLRDQIAAHVFPEVTAEEFAADDHEEKALPLIIRAYERFPMPGYGSAIKRMIDDATKAEVQSKRIKARMLQDAIREVNTKVRLTYINAFGLHTITEKLFSAIHRINKKEIDIAKHDVMRAAAQKRILIPDAEPDTFQLVMDWIYQGKLDCEDPQQLYNTLQLATRLGVTALSEFCHSKLYNAANDSIQDALANGTSLKTLLGYGLGPGDRVLEVVFKHAFKDHDAPKRLREMAVNTLASNLDGELWAEINDVVSHSVALQIIAAMVEYHEQVAEGLLNHDTIKHVDDRARTVSPMAALDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0R9</accession>
    <name>W6Z0R9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBX domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_40525</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Directly interacts with VCP. Interacts with UBQLN1. Forms a complex with VCP and UBQLN1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964111">
        <property type="protein sequence ID" value="EUC41269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692209.1">
        <property type="nucleotide sequence ID" value="XM_007694019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0R9"/>
    <dbReference type="STRING" id="930090.W6Z0R9"/>
    <dbReference type="GeneID" id="19123891"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40525"/>
    <dbReference type="eggNOG" id="KOG2689">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035996_1_0_1"/>
    <dbReference type="OrthoDB" id="2445133at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006986">
        <property type="term" value="P:response to unfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46424">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
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        </location>
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        </location>
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        </source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="481" mass="51700" checksum="B9D4FA5EEDC488AF" modified="2014-04-16" version="1">MFHEGTLQSGISLAIKEQKLVACFVRDDGATSKEWEEEWLTSGWLSSLLAQKAVLLRLEAGSTEAGFLAAFSDLSEIPTFVVIHNGQLQIQLKSHVTKDEFINSIRRVLGANSIPGSNTAPTSPPQAGTLDSPSNHNTAAAEDDLYGNEESYTPTPVEPAAAPSPSANAKGKQRMTSAPTSKPTSSGSVNKAQQEARDALRKKKKEEAEELARVKARIEADKAARRAEAEARKAEREKERNKEAQTSPPPHTIASSSSRGSRAKQVNLNVRLFDGRTIRSTFPREVTLQGEVRKWVDLEFSKLSQDDANINHKQLPPYYFRHILAPQPSRELSAGDESQSLGDIDLAPSATLVLVPVKGYTEAYSGAEGGVVGAATGLVGGAFGLLASTVGFVSNTIGSAIGYASQGASSSSSSSQQQQRPGGGGQTVGSRSSQEPHHDTSNNPGFRVRTLADQRGREPQQFYNGNQLSTEHRPEDNDKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z149</accession>
    <name>W6Z149_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_8887</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        </location>
    </feature>
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        <location>
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        </source>
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        </source>
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        <source>
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        </source>
    </evidence>
    <sequence length="520" mass="57929" checksum="B0A323005148BED3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        </citation>
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        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC45562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="66" mass="7727" checksum="3CE0913794BAB612" modified="2014-04-16" version="1">MAESLPPQPTHHASWEHAWLRHVQQIGMATFVFNWRHFFLLSYRDPRTCLNYPSPALSARLANLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z258</accession>
    <name>W6Z258_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">Heat shock 70 kDa protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="8" type="ORF">COCMIDRAFT_36440</name>
    </gene>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="1 6">Belongs to the heat shock protein 70 family.</text>
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    </dbReference>
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    <dbReference type="eggNOG" id="KOG0101">
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="613"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="613"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="646" mass="70097" checksum="088A29B849EB23B7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z296</accession>
    <name>W6Z296_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Superoxide dismutase</fullName>
            <ecNumber evidence="3 10">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_99783</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="3 10"/>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689653.1">
        <property type="nucleotide sequence ID" value="XM_007691463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z296"/>
    <dbReference type="STRING" id="930090.W6Z296"/>
    <dbReference type="GeneID" id="19129532"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99783"/>
    <dbReference type="eggNOG" id="KOG0876">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031625_2_1_1"/>
    <dbReference type="OrthoDB" id="239262at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.990:FF:000001">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.55.40.20:FF:000002">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF6">
        <property type="entry name" value="SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="11">
        <location>
            <begin position="38"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="12">
        <location>
            <begin position="127"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC43828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="230" mass="25342" checksum="EC7757B44D673B12" modified="2014-04-16" version="1">MNTTLLRTSALRSAARAAAPVTSRAGLAGTTFVRGKATLPDLPYDYGALEPSISGKIMELHHKNHHNTYVTSFNNFSEQIAEAKQKQDIQAQIALQPLINFHGGGHINHTLFWENLAPINQGGGEPPSGALAAAINTNYGSLDAFKEKFNTALAGIQGSGWAWLVQDTQTGGIQIKTYANQDPVVGQFRPILGVDAWEHAYYLDYQNRKAEYFKAIWNVINWKAAEKRFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2C1</accession>
    <name>W6Z2C1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_60969</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964086">
        <property type="protein sequence ID" value="EUC41784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691691.1">
        <property type="nucleotide sequence ID" value="XM_007693501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2C1"/>
    <dbReference type="GeneID" id="19124837"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_60969"/>
    <dbReference type="eggNOG" id="ENOG502SJ6U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008137_0_0_1"/>
    <dbReference type="OrthoDB" id="2571985at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF15">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <source>
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    </evidence>
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    <sequence length="799" mass="89938" checksum="B8FB621951239036" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="108" mass="11197" checksum="BC1071C01941CB6E" modified="2014-04-16" version="1">MTNPHVGAGSVNSAISGGPSMTVQMHTPVPFLTSKVGNWNLYSLNSPGVFDLSMLAAMGGENPTIARSETVSTFDDIFGLDLISGHDMVAVDPILACDHLSSALGTHP</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
        </source>
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            <begin position="1"/>
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        </location>
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    </feature>
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        <location>
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        </location>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="340"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="352" mass="38359" checksum="AD269892B1859A8D" modified="2014-04-16" version="1">MRFSTITLLALGATASAYVVPNRQVVDNAVKARMPENEAVQASNLVAALSARELEARHHQGNKGKGKKNARQEYAPVEARDPEPHHQGNKGKGKKNARDVDSEDHDHEDLEARNPHHQGNKGKGKKNAREASPEPHHQGNKGKGKKNGRDVDSEDHDHEDIVARDPHHQGNKGKGKKNGRDVESEDEDLETRSPHHQGNKGKGKKNAREASPEPHHQGNKGKGAGKKNARDVDSEEHDHEDIVARDPHHQGNKGKGAGKKNARDVDSEDHDHEDLAARDPAPHHQGNKGKGAGKKNARDIDSEEHDHEDIVARDPHHQGNKGKGAGKKNAREASPEPHHQGNKGKGAGKKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4L0</accession>
    <name>W6Z4L0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 125 protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_92277</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688673.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19128045"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92277"/>
    <dbReference type="eggNOG" id="ENOG502QR7D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023537_2_1_1"/>
    <dbReference type="OrthoDB" id="7771656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047:SF1">
        <property type="entry name" value="DUF1237 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028846">
        <property type="entry name" value="UCP028846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889520" evidence="1">
        <location>
            <begin position="20"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="513" mass="56865" checksum="61B65C740CB63AB7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z570</accession>
    <name>W6Z570_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 20</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Mediator complex subunit 20</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MED20</name>
        <name evidence="5" type="ORF">COCMIDRAFT_5856</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the Mediator complex subunit 20 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688569.1">
        <property type="nucleotide sequence ID" value="XM_007690379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z570"/>
    <dbReference type="STRING" id="930090.W6Z570"/>
    <dbReference type="GeneID" id="19124756"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5856"/>
    <dbReference type="eggNOG" id="ENOG502SBIU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1161505_0_0_1"/>
    <dbReference type="OrthoDB" id="1854899at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013921">
        <property type="entry name" value="Mediator_Med20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08612">
        <property type="entry name" value="Med20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="265" mass="29181" checksum="FBF8555F2CE99B3E" modified="2014-04-16" version="1">MKYSGLYFISNPSTSVEAALSTITTLTQSIESTFQTATRQQPWSLSYRAFRDVIPPGYTPPTGADGKPAPYPHSYQHMLHLSTLAPTRTYIYAQPAAQPATTASIPLRQQEAHASMLRNQSSALWAQRHVFSVRDGTTYTAGLCTIQLGELRATREGPQSGAMLSPGIILCITTLVGAEDADEGPDAAYAAVENGAPLDAVEQGDVDFEYAQKVIRECWGRIKEGRDLGRSEVREFMMAARVEVKRELQRDQAVHMWCDALRIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5B3</accession>
    <name>W6Z5B3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cdc23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_25019</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC46957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686460.1">
        <property type="nucleotide sequence ID" value="XM_007688270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5B3"/>
    <dbReference type="STRING" id="930090.W6Z5B3"/>
    <dbReference type="GeneID" id="19120690"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25019"/>
    <dbReference type="eggNOG" id="KOG1155">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018320_2_1_1"/>
    <dbReference type="OrthoDB" id="10262026at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007192">
        <property type="entry name" value="APC8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF10">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04049">
        <property type="entry name" value="ANAPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cdc23" evidence="9">
        <location>
            <begin position="11"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="380"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="414"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="448"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="40"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC46957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="649" mass="72752" checksum="2EB3593AC06BC6BB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5F0</accession>
    <name>W6Z5F0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="10">dUTPase</shortName>
            <ecNumber evidence="10">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_96284</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="function">
        <text evidence="2">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>dUTP + H2O = dUMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the dUTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="10"/>
    <dbReference type="EMBL" id="KI963989">
        <property type="protein sequence ID" value="EUC45180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688308.1">
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        </source>
    </evidence>
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    </evidence>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45180.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="184" mass="18749" checksum="493F4DBF1EAAE956" modified="2014-04-16" version="1">MSSVLQPPAPIAPSIAAGAAAEQQLQVQLLSANAKAPTKGSAFAAGHDLYSAVDVVIPARGRKLVGTDIKISVPVGTYGRVAPRSGLAYKHGIDTMAGVIDADYRGPVGVILANLSDEDFEVKIGDRIAQLVVEKIAMPNVVVVEELEQSVRGAGGFGSTGGFGTATAAAAEPAVAAETEEKKE</sequence>
</entry>
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    <accession>W6Z5I8</accession>
    <name>W6Z5I8_COCMI</name>
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        <name evidence="2" type="ORF">COCMIDRAFT_102510</name>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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        <location>
            <begin position="19"/>
            <end position="189"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="20067" checksum="2C279317BE8D5D18" modified="2014-04-16" version="1">MFSKTTLLMALNAGLTLAGNAILTNRCSYDIWVSSVGGTHQTPCTLVPARTQYTEVLYNTGTSLKISSTDSIKNGEHTQFEYSIAGGKIWYDISFVNCAEGDSASACPGHAEGLAMRGTDDQCSAADCAAGDYCPTQAYYVDTPLIKLGLKEPVFDCPTADVDLHMTVCSGEDSLKRSVAGRVAIDLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5K3</accession>
    <name>W6Z5K3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_26560</name>
    </gene>
    <organism evidence="4 5">
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690040.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_26560"/>
    <dbReference type="eggNOG" id="ENOG502RFPC">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_324429_0_0_1"/>
    <dbReference type="OrthoDB" id="3789140at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="678"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="759"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="802"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="870"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="272"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="594"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="706"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="905" mass="101436" checksum="662F8B1F1D3F9D27" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z610</accession>
    <name>W6Z610_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sacsin/Nov domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_96023</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688248.1">
        <property type="nucleotide sequence ID" value="XM_007690058.1"/>
    </dbReference>
    <dbReference type="GeneID" id="19128772"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96023"/>
    <dbReference type="eggNOG" id="ENOG502QPMA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001744_1_0_1"/>
    <dbReference type="OrthoDB" id="10031156at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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            <end position="1475"/>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
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            <end position="39"/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
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                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
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                <person name="Salamov A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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</entry>
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            <taxon>Dothideomycetes</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Mem_trans"/>
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    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
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        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
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        </location>
    </feature>
    <feature type="domain" description="Choline kinase N-terminal" evidence="7">
        <location>
            <begin position="794"/>
            <end position="861"/>
        </location>
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        <location>
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    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="5">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">ATCC 44560</strain>
        </source>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
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                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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            <strain evidence="1 2">ATCC 44560</strain>
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    </evidence>
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    </evidence>
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</entry>
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    <accession>W6Z7W1</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="6">Component of the GINS complex.</text>
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    </dbReference>
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        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF3 N-terminal" evidence="8">
        <location>
            <begin position="5"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="75"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="179" mass="19735" checksum="FEDA1F70D026A10F" modified="2014-04-16" version="1">MSSYYDVDAILTDAQKVPCTFELTVPGLGYLEGNMNGDMKQGSKVELPLWLGEMLALSQSLNTSSLVTIDPPSALSPRVLNALKADPRTVDLRALAPHFYNLGARILELFEEEEIIEVLSDTFKARAALIADQAHNPRGALGEGADFMRGLDENERQLFRAAHDSAKGVRTWMTDLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8U4</accession>
    <name>W6Z8U4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_38169</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964015">
        <property type="protein sequence ID" value="EUC43974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689525.1">
        <property type="nucleotide sequence ID" value="XM_007691335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8U4"/>
    <dbReference type="GeneID" id="19123415"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38169"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF12">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="480"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="56664" checksum="C7FB6FD1AD6EBD2C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z948</accession>
    <name>W6Z948_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavoprotein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_99125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964012">
        <property type="protein sequence ID" value="EUC44084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689420.1">
        <property type="nucleotide sequence ID" value="XM_007691230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z948"/>
    <dbReference type="STRING" id="930090.W6Z948"/>
    <dbReference type="GeneID" id="19129404"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99125"/>
    <dbReference type="eggNOG" id="KOG0672">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019412_0_0_1"/>
    <dbReference type="OrthoDB" id="70387at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071513">
        <property type="term" value="C:phosphopantothenoylcysteine decarboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359:SF21">
        <property type="entry name" value="FLAVOPROTEIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359">
        <property type="entry name" value="HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="3">
        <location>
            <begin position="11"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="581" mass="66162" checksum="B839ED0C4797B3A4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z979</accession>
    <name>W6Z979_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CT20 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_4599</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF7 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963968">
        <property type="protein sequence ID" value="EUC46323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z979"/>
    <dbReference type="STRING" id="930090.W6Z979"/>
    <dbReference type="GeneID" id="19124301"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4599"/>
    <dbReference type="eggNOG" id="KOG4051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="5595141at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012423">
        <property type="entry name" value="Eaf7/MRGBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581">
        <property type="entry name" value="MRG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581:SF5">
        <property type="entry name" value="MRG_MORF4L-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07904">
        <property type="entry name" value="Eaf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="185"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="190"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC46323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="31214" checksum="A3C4FC66023420DD" modified="2014-04-16" version="1">MPPRKKAKASAASTPLGDTQPKTPQDSGAVQAQDEILSDPWADEQETQLLKSMMKWKPTGLHKHFRMISIHTDMRSHGFAGEDAPHTRIPGIWKKLSQWYDLDALDTRENEFAFSDEPDPLDPDDAANLPEFELPEEEFGEMMWRKRFHSPDSVVASSPPMVPTDEYKDIYAPGIGLLKYLPDGVRSQKAESVTEATSTPKNTKGARPARAAKSTKSARSVANAARNAKPRSTVSESAEEEDDDEDEEESSVESEEDSAPTTRRTNRAKPKPAPKRTRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9H5</accession>
    <name>W6Z9H5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_92773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9H5"/>
    <dbReference type="GeneID" id="19128138"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92773"/>
    <dbReference type="HOGENOM" id="CLU_2497556_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="86" mass="9499" checksum="650677C8D4FE3715" modified="2014-04-16" version="1">MPWKGSDTGLFLRCRHVSWLKRTLNILGQGQGRWRTSATGTRHDWPISPSAPDRPGVHGVSSLVPSPLRPFGIMPRPTPNHALAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9Q6</accession>
    <name>W6Z9Q6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_92208</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686796.1">
        <property type="nucleotide sequence ID" value="XM_007688606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9Q6"/>
    <dbReference type="GeneID" id="19128032"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92208"/>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_0_1_1"/>
    <dbReference type="OrthoDB" id="2410195at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="72"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="281"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="475" mass="52806" checksum="72E05A86FE1E1411" modified="2014-04-16" version="1">MDPNSTTTKLAQLEALLNSALTTLGASSGDYKDSLPPRALFDAQRTILAAVGMVTELVSTPSVRLLEVSMQYFEARALHIAAEKRIPDMLAGHNENGVAVKELAEQAGCDALKLSRIMRCLCSIHIFKEVQPERFANNEVSAALVNNEPLRAYIVMFAFDMYSASDHLPRSLFDKKMGPSYDVAETAFQKALGTHKPRWEWFEEKITVQDLLDGRCGTDGGQSGYPGPFGSELDKAVEGKAGSELIVRPELPNFGLAMVGGGRILGKAHIYDYPWESLGSARVVDVGGGVGGFCLQLSQVYPHLQFVVQDRAPVLEQAETVIWPKENPEAIAQERVQFCPHDFFEPNPVKEAEVYWLRYIMHDWSDEYCVRILKAIKPSMGPRSRILVCDQVMNTTLGSEELTAAPSPLPANWGYYTRYSHQRDLALMAAINGIERTPREFRALIEKSGLKLLKIWDCRSQVSLVEIVLPESELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9U8</accession>
    <name>W6Z9U8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_37850</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC44299.1"/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="entry name" value="NUDIX_hydrolase_dom"/>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="183" mass="20555" checksum="A020382F1C88E6D2" modified="2014-04-16" version="1">MTTPKPLEYSADLQEFAISAPEYLSQHTQHDVLVTGAVVFDKDGKILLVQRAADEKAFPDFWEIPGGKVEDDDETILHAAARELKEETGLRAIRVLRKVAQFTFGDEKPGRPTTRWLKLIFEMEVDHADAVVLDPVEHQRFVFASEEEVVNDRAGEMVFKYINATNKAVKLEAFKGRGAAQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAI1</accession>
    <name>W6ZAI1_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_91974</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
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                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC46803.1"/>
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    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="1717591at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072318">
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13 14">ATCC 44560</strain>
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        <text evidence="1 11">Required for nuclear membrane fusion during karyogamy.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
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        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the KAR5 family.</text>
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    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="Nuclear_fusion_Kar5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28012">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN KAR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28012:SF1">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN KAR5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tht1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
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            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="503"/>
            <end position="527"/>
        </location>
    </feature>
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        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00003389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC49147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="65051" checksum="FB144FF8D0A2D400" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBP7</accession>
    <name>W6ZBP7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GTP cyclohydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_24843</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686238.1">
        <property type="nucleotide sequence ID" value="XM_007688048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBP7"/>
    <dbReference type="STRING" id="930090.W6ZBP7"/>
    <dbReference type="GeneID" id="19120649"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24843"/>
    <dbReference type="eggNOG" id="KOG1284">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029639_1_0_1"/>
    <dbReference type="OrthoDB" id="57939at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005536">
        <property type="entry name" value="PRK07198.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259:SF2">
        <property type="entry name" value="URACIL-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase N-terminal" evidence="6">
        <location>
            <begin position="104"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="5">
        <location>
            <begin position="329"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="57145" checksum="76BA98861C7E9C40" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC58</accession>
    <name>W6ZC58_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_84723</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LIMR family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684123.1">
        <property type="nucleotide sequence ID" value="XM_007685933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC58"/>
    <dbReference type="STRING" id="930090.W6ZC58"/>
    <dbReference type="GeneID" id="19126519"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84723"/>
    <dbReference type="eggNOG" id="KOG2296">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016542_1_0_1"/>
    <dbReference type="OrthoDB" id="203099at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051584">
        <property type="entry name" value="GPCR-associated_LMBR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355:SF0">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="490"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="568"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="654"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="585"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="663"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="697" mass="78077" checksum="68D70BF406BA81D8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCS2</accession>
    <name>W6ZCS2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome assembly protein 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Notchless protein homolog 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosome biogenesis factor RSA4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_29707</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NLE1/RSA4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964098">
        <property type="protein sequence ID" value="EUC41536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691945.1">
        <property type="nucleotide sequence ID" value="XM_007693755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCS2"/>
    <dbReference type="STRING" id="930090.W6ZCS2"/>
    <dbReference type="GeneID" id="19121554"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29707"/>
    <dbReference type="eggNOG" id="KOG0271">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_16_1"/>
    <dbReference type="OrthoDB" id="10267436at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110136">
        <property type="term" value="P:protein-RNA complex remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000092">
        <property type="entry name" value="notchless protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF0">
        <property type="entry name" value="NOTCHLESS PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="137"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="180"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="223"/>
            <end position="261"/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
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                <person name="Ohm R.A."/>
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                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693346.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_104794"/>
    <dbReference type="eggNOG" id="ENOG502S3NW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173507_0_0_1"/>
    <dbReference type="OrthoDB" id="5341873at2759"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10250" checksum="043B8D140B5F917C" modified="2014-04-16" version="1">MPTPIDRAVQQRGPFFAFAAIVAGVAAWSIWGQDIFPSQDPTGDPETWTHDQCVTWLQHRNLHPSPLATTAELLERIKANMRVSRERAPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF31</accession>
    <name>W6ZF31_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_36207</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963971">
        <property type="protein sequence ID" value="EUC46119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687346.1">
        <property type="nucleotide sequence ID" value="XM_007689156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF31"/>
    <dbReference type="STRING" id="930090.W6ZF31"/>
    <dbReference type="GeneID" id="19122974"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36207"/>
    <dbReference type="eggNOG" id="ENOG502T06K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_273523_0_0_1"/>
    <dbReference type="OrthoDB" id="3045089at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="3">
        <location>
            <begin position="1000"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="459"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="546"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="819"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1062"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="660"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="546"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="843"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="855"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1077"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1098"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1146"/>
            <end position="1157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1191" mass="135040" checksum="45B0B0728762BB06" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF89</accession>
    <name>W6ZF89_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_86695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC48670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684884.1">
        <property type="nucleotide sequence ID" value="XM_007686694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF89"/>
    <dbReference type="GeneID" id="19126911"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86695"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_2_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF156">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="54001" checksum="0C4049D9493C02F7" modified="2014-04-16" version="1">MALQDLVFGVIGAHVALTATLTPFLILFLRSIYRIYFHPLAHIPGPVLSKLTSLWLHYHAYIGDEASVIHKLHQEYGPYVRVSPNEVDLSDADGIPAIYVSKGGFPKAKCYANFDIDGHKTIFSTTNQEYRAHRAKAVLPLFSTKSLRENEQAIWGCVDCMVDRLKEEAKSKRPVNVLNLARSLAVDAVSTHLFRENYDGVSEKGPVLSASAFVDAFVAVGRFFYLPNIAFVWLEWVVEKWAPDRETDDSMSLVDKFVATLVGNTTSKSTTYPGRLLAIGLSDSEVRAQCKDLIFAGTDSTGMNLATIMRSLVLHPEKYQRLKEEFTKNAALGPDAQDAQALPYLNAVVKEGLRLSMANPTRLPHVVPAGGWTFKGTYFPADSLIGCSAYELHFNSIVFPQPQEFIPERWLNTTEEMSKYWFAFGAGSRACIARNLATMELQFATERLAKTGVLDGAKVVQKEVEIYEWFNSKVKGGKIELVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFC4</accession>
    <name>W6ZFC4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_81560</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the proteasome inhibitor PI31 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682883.1">
        <property type="nucleotide sequence ID" value="XM_007684693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFC4"/>
    <dbReference type="STRING" id="930090.W6ZFC4"/>
    <dbReference type="GeneID" id="19125896"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81560"/>
    <dbReference type="eggNOG" id="ENOG502RZMJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044125_2_0_1"/>
    <dbReference type="OrthoDB" id="68090at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045128">
        <property type="entry name" value="PI31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013886">
        <property type="entry name" value="PI31_Prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021625">
        <property type="entry name" value="PI31_Prot_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13266">
        <property type="entry name" value="PROTEASOME INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13266:SF1">
        <property type="entry name" value="PROTEASOME INHIBITOR PI31 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08577">
        <property type="entry name" value="PI31_Prot_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11566">
        <property type="entry name" value="PI31_Prot_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI31 proteasome regulator N-terminal" evidence="13">
        <location>
            <begin position="29"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="PI31 proteasome regulator C-terminal" evidence="12">
        <location>
            <begin position="272"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="184"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="355"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC50557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="385" mass="40839" checksum="D3C54F39063E475C" modified="2014-04-16" version="1">MVQTNTTGNPLSAGSLALFMATSLPKGEASQLKNGTEAVALAVHAGMLAVGFRLIGLGEDERIEAHADAQDPKELPVQWNASSSYAFRYAHAQSAMEFLVKVNRLGGKAVVFALAVGDDKTTHFELTTKDYLSESQLPFSVPEGTSIEDASQKLQDLFISAGRLNDLGSLLKISVIQKLAPRLNKPGYEESTTDQERTPTADRQDPQRSDPPNPRQPPADPDPARPHPFNDPLAAPPRSGRHLPEPIPGFDDELDLNRGPGRLRDNRNPINIGHDDLYPQGLGPNDPLRPHLAGGLPRPGGFGGGGMHPTFDDPLFRGQGGQGGYDPMAPPGARYDTFGPGDPRAEDRGRVPRFPGGGGDGFGGPGGFGGRPPNPFGGFGGGDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFV0</accession>
    <name>W6ZFV0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_93003</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687133.1">
        <property type="nucleotide sequence ID" value="XM_007688943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFV0"/>
    <dbReference type="STRING" id="930090.W6ZFV0"/>
    <dbReference type="GeneID" id="19128182"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93003"/>
    <dbReference type="eggNOG" id="KOG2730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029658_0_1_1"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000270">
        <property type="entry name" value="RNA methylase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="240" mass="27386" checksum="E3D5A5DCA06B85A5" modified="2014-04-16" version="1">MSDNGDENDVDQWSRVEQFPEHLKKYWFQRFKIWENYDQGIWMTEDAWFGVTPEPIANKIAAHIAESAPKEKTVIVDAFAGVGGNAIALARSGRWERVFAIEKDARTLKCAKHNAEIYGVSNKIFWLNADCFDAINRFSGQKNVVVFASPPWGGTEYGAENVFDLTKMEPYNLDKLYKAFTKVSNEVVLYLPRTSDLNQIAKYGQDGKKLEVAHYAMMGASKALCVYFGDFDFEMEEENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGD7</accession>
    <name>W6ZGD7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684462.1">
        <property type="nucleotide sequence ID" value="XM_007686272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGD7"/>
    <dbReference type="GeneID" id="19126713"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85696"/>
    <dbReference type="eggNOG" id="ENOG502RIBX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_871957_0_0_1"/>
    <dbReference type="OrthoDB" id="3793088at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="250"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="316" mass="35575" checksum="157289F0DC9E402C" modified="2014-04-16" version="1">MATATYIASKNLAEIREQLGEPFATALEYLPLDKVITKTQKHEEDAISFMLLFGHIRNQCENGDRDVWVLLFPPTKEDGQSKIEFNSYDSATGASEWHNNHNISTSAENAAAFKMPKKASLGKHTALARYYFLQKLAANETKNDGISELKFAMKVNRGLLDCLKTACNEFEGAAKAALARSVRQLSVTLPESQESDATLDFEDSRETVNERLQRAWAPQTPLNKIAQALASLNDKEMNVKTRITNLDDYLMTLTEERLDLEQRCKNVEAERLAAEKEVASIKAQRETLFKGLSPEAVFELGRNSERTNPTKRRKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHP3</accession>
    <name>W6ZHP3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 94 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_91639</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686593.1">
        <property type="nucleotide sequence ID" value="XM_007688403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHP3"/>
    <dbReference type="GeneID" id="19127921"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91639"/>
    <dbReference type="eggNOG" id="ENOG502RNEZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019054_0_0_1"/>
    <dbReference type="OrthoDB" id="5337493at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11748">
        <property type="entry name" value="GH94N_NdvB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000046">
        <property type="entry name" value="Cellobionic acid phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="entry name" value="Glycoside hydrolase, family 65, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="GH65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033432">
        <property type="entry name" value="GH94_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052047">
        <property type="entry name" value="GH94_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037814">
        <property type="entry name" value="GH94N_CBAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010383">
        <property type="entry name" value="Glyco_hydrolase_94_b-supersand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37469:SF2">
        <property type="entry name" value="CELLOBIONIC ACID PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37469">
        <property type="entry name" value="CELLOBIONIC ACID PHOSPHORYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06165">
        <property type="entry name" value="GH94_b-supersand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17167">
        <property type="entry name" value="Glyco_hydro_94"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl hydrolase 94 supersandwich" evidence="3">
        <location>
            <begin position="70"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase 94 catalytic" evidence="4">
        <location>
            <begin position="312"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="810" mass="91603" checksum="10459C26140D961C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHT6</accession>
    <name>W6ZHT6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_91275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC46969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686494.1">
        <property type="nucleotide sequence ID" value="XM_007688304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHT6"/>
    <dbReference type="GeneID" id="19127850"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91275"/>
    <dbReference type="HOGENOM" id="CLU_133010_0_0_1"/>
    <dbReference type="OrthoDB" id="3682439at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="176" mass="19921" checksum="0EC3C4155CEA6F47" modified="2014-04-16" version="1" fragment="single">IKMSRHNRHICRHTHHICRHGHAAHSIPFGPMRLAPVPSPVQPGQPAPTATEWNYTLQDFEELIIKWGPYTTLDLVKAAPHYTKTTVDVDPYAKLQFPEKWEATERVIHAVHPIPRGELEKLGPNCVRQLGERLKGGGEGRDEEFEGAMKKTLGRIDDCLEFYFCVERPGARVVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIM6</accession>
    <name>W6ZIM6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_83749</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683698.1">
        <property type="nucleotide sequence ID" value="XM_007685508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIM6"/>
    <dbReference type="STRING" id="930090.W6ZIM6"/>
    <dbReference type="GeneID" id="19126317"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83749"/>
    <dbReference type="eggNOG" id="KOG0114">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_25_2_1"/>
    <dbReference type="OrthoDB" id="275748at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12241">
        <property type="entry name" value="RRM_SF3B14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000286">
        <property type="entry name" value="Putative pre-mRNA branch site protein p14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034150">
        <property type="entry name" value="SF3B6_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="25"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="127" mass="14473" checksum="CE2E87DABE02145A" modified="2014-04-16" version="1" fragment="single">PPAALPITSQFFTVYNRRQSMSRGGKLAPEVNRFNVTPEELFDLFGKFGPVRQIRQGIANHSKGTAFVVYEDVMDAKSACDKLNGFNFQNRYLVVLYHQPDKMLKAANDLAERQENLEKLKKQHGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIW3</accession>
    <name>W6ZIW3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_3613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686052.1">
        <property type="nucleotide sequence ID" value="XM_007687862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIW3"/>
    <dbReference type="STRING" id="930090.W6ZIW3"/>
    <dbReference type="GeneID" id="19122951"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3613"/>
    <dbReference type="HOGENOM" id="CLU_002639_8_3_1"/>
    <dbReference type="OrthoDB" id="5428863at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="60"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="383" mass="43297" checksum="A1F0DC5F35F8A9F2" modified="2014-04-16" version="1">MRIVSLLEQCDGHHSKYRSSHPPRRPTRLLRIGIDQQSNQLYVYLDTGSDQEHKLTVSLFKTLRIELAVSELPRILQDAFLSSWNHDVRFIWMNYLCIFQNNEKDLAREIADLPAISDNAHITIPASGADDSRDNFLNRTSRSPVQGIVWSLSYACTDGIYTIAADFRIHVIWARMDVSRDGTASRRGVRSWEDMHQLFLSLYRGIKEGSDVKECEIWMKLVWNDSRRALKCPADKIPATSGIADLWSRRMLNDTCLAGLWHYQIPLALLWICDQQSEQLDDTYRTPSWKSASLKGLATWNRAMITDIDPELEVVASNIKLVHVELPYGAVASGSLTVQGHFCRGIPSLSAPNCLDSEYIGGKSFAPIDLLSDSSESTLPVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ48</accession>
    <name>W6ZJ48_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type 1 phosphatases regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_82818</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the YPI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683441.1">
        <property type="nucleotide sequence ID" value="XM_007685251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ48"/>
    <dbReference type="STRING" id="930090.W6ZJ48"/>
    <dbReference type="GeneID" id="19126134"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82818"/>
    <dbReference type="eggNOG" id="KOG4102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098333_0_1_1"/>
    <dbReference type="OrthoDB" id="307488at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011107">
        <property type="entry name" value="PPI_Ypi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07491">
        <property type="entry name" value="PPI_Ypi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="165" mass="18104" checksum="4D6DDC081EE8A6E7" modified="2014-04-16" version="1">MAAHQRTTSPRTVTPSAGSRTIQIRPAPVLRLSAPSGVLRLRAEPTERRHIQWAEDVVDNEGMGKKSSKVCCIYHKPRAVDESSDDDSSDSSSSDSDSDSEPDNSTARPAGRIGAARGRRPHQHDHDGCAENHGCNEGSGQPQKTKRQRRKPSPNAYEKMPKQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ99</accession>
    <name>W6ZJ99_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_89842</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685939.1">
        <property type="nucleotide sequence ID" value="XM_007687749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ99"/>
    <dbReference type="GeneID" id="19127558"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89842"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="296"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="14"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="528" mass="57842" checksum="AE39483C0CDD0441" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJP6</accession>
    <name>W6ZJP6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">triacylglycerol lipase</fullName>
            <ecNumber evidence="6">3.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Autophagy-related protein 15</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">COCMIDRAFT_988</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17855"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
            <location evidence="3">Multivesicular body membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Prevacuolar compartment membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="6"/>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683112.1">
        <property type="nucleotide sequence ID" value="XM_007684922.1"/>
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    <dbReference type="STRING" id="930090.W6ZJP6"/>
    <dbReference type="GeneID" id="19129333"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_988"/>
    <dbReference type="eggNOG" id="KOG4540">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028295_0_1_1"/>
    <dbReference type="OrthoDB" id="58570at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032585">
        <property type="term" value="C:multivesicular body membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005775">
        <property type="term" value="C:vacuolar lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034496">
        <property type="term" value="P:multivesicular body membrane disassembly"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046461">
        <property type="term" value="P:neutral lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006660">
        <property type="term" value="P:phosphatidylserine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000129">
        <property type="entry name" value="Autophagy related lipase Atg15, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050805">
        <property type="entry name" value="ATG15_Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175:SF2">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887141" description="triacylglycerol lipase" evidence="20">
        <location>
            <begin position="30"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="21">
        <location>
            <begin position="278"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="568"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="572"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="584"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EUC50265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="634" mass="69616" checksum="089DF02C12454FAB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKM6</accession>
    <name>W6ZKM6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_38019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689364.1">
        <property type="nucleotide sequence ID" value="XM_007691174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKM6"/>
    <dbReference type="GeneID" id="19123375"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38019"/>
    <dbReference type="HOGENOM" id="CLU_1454247_0_0_1"/>
    <dbReference type="OrthoDB" id="3693455at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="173" mass="18477" checksum="31C0DFA7EA9FA60E" modified="2014-04-16" version="1">MVEKTRQEESFLEACCVDRVSTLETVGSIPLSGVDPIGRVPALSMVGGCGEDSTGQECHVEAVGPWSCVCEDEDHGSSHRGQASSVSTRAEALAIEWYAGGLDATTPVVSQQRTWFCSVVKTTDKTDKTEQAVEAVALPAGPVASARHAGDEVTWAKWHGHSASAEQPLRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKW2</accession>
    <name>W6ZKW2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_81393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682949.1">
        <property type="nucleotide sequence ID" value="XM_007684759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKW2"/>
    <dbReference type="GeneID" id="19125859"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81393"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_6_1_1"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF8">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="67099" checksum="0D902D4567BB9D9C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL43</accession>
    <name>W6ZL43_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pre-mRNA-splicing factor SYF1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Pre-mRNA-splicing factor syf1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_81267</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in pre-mRNA splicing and cell cycle progression.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682761.1">
        <property type="nucleotide sequence ID" value="XM_007684571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL43"/>
    <dbReference type="STRING" id="930090.W6ZL43"/>
    <dbReference type="GeneID" id="19125837"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81267"/>
    <dbReference type="eggNOG" id="KOG2047">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007736_0_0_1"/>
    <dbReference type="OrthoDB" id="10067343at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000666">
        <property type="entry name" value="DNA repair and transcription protein (Xab2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000023">
        <property type="entry name" value="Pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000182">
        <property type="entry name" value="Pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000038">
        <property type="entry name" value="Putative pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056350">
        <property type="entry name" value="HAT_Syf1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23220">
        <property type="entry name" value="HAT_Syf1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="15">
        <location>
            <begin position="33"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor SYF1 central HAT repeats" evidence="13">
        <location>
            <begin position="196"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="14">
        <location>
            <begin position="411"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="774"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="783"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC50790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="837" mass="96937" checksum="69F46BC2851E11DE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL75</accession>
    <name>W6ZL75_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Folliculin-interacting protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_80952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50698.1"/>
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</entry>
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                <person name="Bushley K.E."/>
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
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                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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                <person name="Han J."/>
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        <location>
            <begin position="424"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="55041" checksum="60260DDCB55AA024" modified="2014-04-16" version="1">MTLRDTYARFLATPSTGALAENATLHYVSTTTSISDATAIIKHLSVQEKLLKKTKQNILDAVEGSRALSVDVETTIEFSNGGGAYLPGLDDNFVADRTATFPMVHVVHFDHAGKITQIRQYWDQGSLLKQIDVIGARSRNWPIRDASEQIRLISNNASASQPESAASSRPTTSASRGADEVSISSRSQRSTSNAMNDPHASLSLFAPRETEEEPSYTGQPGAPRAQSAKPPPREYSELFAAAEGGSPTPSQKIPTKSGAGKNYKPNRLFDEDDDESVPSAPSSVKTNSKKYDHFQFGDGEETPKAPEALRPRQNQLRTKNSAHWDFDDFATPDKAKPKTHPQAVRHFGWSDDEDDVSPVRRPIVHKARPDADAHFEFNDDGTPEGQRARPIKGKQGNKGQGLYDDHVTNTTVDSPAAAKKENIKSTQAVRSSMKTHWGTHADSPENRGINIAGNGMGGRKGTEAAWSLFDESPAKKEATGNKQAGIKTEGDGMGGRKTADKSFWDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLN5</accession>
    <name>W6ZLN5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Arp2/3 complex 34 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_31776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682537.1">
        <property type="nucleotide sequence ID" value="XM_007684347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLN5"/>
    <dbReference type="STRING" id="930090.W6ZLN5"/>
    <dbReference type="GeneID" id="19121958"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31776"/>
    <dbReference type="eggNOG" id="KOG2826">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059439_1_0_1"/>
    <dbReference type="OrthoDB" id="148331at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072697">
        <property type="term" value="P:protein localization to cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000003">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000005">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007188">
        <property type="entry name" value="ARPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058">
        <property type="entry name" value="ARP2/3 COMPLEX 34 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04045">
        <property type="entry name" value="P34-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="318" mass="36376" checksum="13986AAD4199DA33" modified="2014-04-16" version="1">MLLLDYQNVLIESLLRDRVNGGAPANIDQVVSDFDGVTFHISTPETKTKILVSLHIKCFKELVQYGAQAVLEREYGPFIVEPESGYDFSVLVDLENLPEDQDAKDDLVRRVALLKRNAMAAPFEQAFDEFHQLQEEASKYTSESAPQGVAEGGDVRAIHYREEEAIYVKASHDRVTVIFSTVFREETDRIFGKVFLQEFVDARRRAIQNAPQVLFRNDPPLELQGIPGVDTSGSADIGYITFVLFPRHLTNQRRADVISHIQTFRDYFHYHIKASKAFIHSRMRKRTADFLQVLRRARPEAEEKERKTASGRTFKVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLV9</accession>
    <name>W6ZLV9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6594 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682299.1">
        <property type="nucleotide sequence ID" value="XM_007684109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLV9"/>
    <dbReference type="GeneID" id="19121265"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_282"/>
    <dbReference type="eggNOG" id="ENOG502S5VZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051118_0_0_1"/>
    <dbReference type="OrthoDB" id="3533814at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046529">
        <property type="entry name" value="DUF6594"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502:SF4">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34502">
        <property type="entry name" value="DUF6594 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20237">
        <property type="entry name" value="DUF6594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6594" evidence="2">
        <location>
            <begin position="22"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="316" mass="35347" checksum="B31C6B7EC79B851C" modified="2014-04-16" version="1">MPQNHRSDVETGHEQIRPLDGFPSLANFISSDPDRTSLVFHRFDRLAARNLLYFQSELAALEARLEHTDSQDCSIEFGDADTQECAKSWELFHGVAEGGSNPRQKARMDLVFEVRQKLKEYREALIFESTLASLGPPPVRTFDAIHHAATRYDKALKQRESIMTGSSAKLYTTNEDLVVLKQPEFEDRLTSFVHRYLPVFFMAERREDNMAYILEKRIARFVTILSVLITVILLFVAILALYYISNPTVKLIMVGVFMLLFAGSVGLFTTAKRSEVFAATAGYAAVLVVFVSGNLGSDPWPSGLWSGGNCTCTGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM57</accession>
    <name>W6ZM57_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_31709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682377.1">
        <property type="nucleotide sequence ID" value="XM_007684187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM57"/>
    <dbReference type="STRING" id="930090.W6ZM57"/>
    <dbReference type="GeneID" id="19121942"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31709"/>
    <dbReference type="eggNOG" id="ENOG502SB4N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014048_2_1_1"/>
    <dbReference type="OrthoDB" id="1744869at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="580" mass="63645" checksum="F458967A304D7EF2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM63</accession>
    <name>W6ZM63_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_31637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682353.1">
        <property type="nucleotide sequence ID" value="XM_007684163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM63"/>
    <dbReference type="GeneID" id="19121916"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31637"/>
    <dbReference type="HOGENOM" id="CLU_2497558_0_0_1"/>
    <dbReference type="OrthoDB" id="3691509at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="86" mass="9805" checksum="54A7AC31F331B3AB" modified="2014-04-16" version="1">MRSWRQRALYEPEWATDDCYSLPLSLTLTFLIFLSSCFLFLSKFCNNCCASFCYRKPRLASYQHPIGSNDVTAPTAGTPTCNGRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP24</accession>
    <name>W6ZP24_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_85164</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684232.1">
        <property type="nucleotide sequence ID" value="XM_007686042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZP24"/>
    <dbReference type="STRING" id="930090.W6ZP24"/>
    <dbReference type="GeneID" id="19126614"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85164"/>
    <dbReference type="eggNOG" id="ENOG502S3FT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026731_1_0_1"/>
    <dbReference type="OrthoDB" id="26149at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040144">
        <property type="entry name" value="RAP1GDS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10957">
        <property type="entry name" value="RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="637"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="727"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="642"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="653"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="665"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="746" mass="82055" checksum="7D28F2AC3272E294" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPW0</accession>
    <name>W6ZPW0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcineurin subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Calcineurin regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Protein phosphatase 2B regulatory subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_95048</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Composed of a catalytic subunit (A) and a regulatory subunit (B).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the calcineurin regulatory subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687844.1">
        <property type="nucleotide sequence ID" value="XM_007689654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPW0"/>
    <dbReference type="SMR" id="W6ZPW0"/>
    <dbReference type="STRING" id="930090.W6ZPW0"/>
    <dbReference type="GeneID" id="19128569"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95048"/>
    <dbReference type="eggNOG" id="KOG0034">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061288_10_1_1"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005955">
        <property type="term" value="C:calcineurin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004723">
        <property type="term" value="F:calcium-dependent protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071444">
        <property type="term" value="P:cellular response to pheromone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000747">
        <property type="term" value="P:conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006873">
        <property type="term" value="P:intracellular monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000047">
        <property type="entry name" value="Calcineurin subunit B type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45942">
        <property type="entry name" value="PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="131"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="174" mass="19751" checksum="AFCE2DCF6AA50A7B" modified="2014-04-16" version="1">MGNQQSGLLDNIASGSNFDREEVDRLRKRFMKLDKDNSGTIERDEFLALPQISSNPLATRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFRVYDIDRDGYISNGELFIVLKMMVGSNLKDQQLQQIVDKTIMEADLDRDGKISFEEFTKMVENTDVSMSMTLDQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ61</accession>
    <name>W6ZQ61_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zinc-ribbon 15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_47977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687687.1">
        <property type="nucleotide sequence ID" value="XM_007689497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ61"/>
    <dbReference type="STRING" id="930090.W6ZQ61"/>
    <dbReference type="GeneID" id="19124380"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_47977"/>
    <dbReference type="eggNOG" id="ENOG502SDGY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115926_0_1_1"/>
    <dbReference type="OrthoDB" id="5545479at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28139">
        <property type="entry name" value="UPF0768 PROTEIN YBL029C-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28139:SF1">
        <property type="entry name" value="UPF0768 PROTEIN YBL029C-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="10088" checksum="254FC40E36CD2896" modified="2014-04-16" version="1" fragment="single">MFFFFTCGTHTFTSQLKGAEHVQVQCQNCGNYRTAVMKRWEWFTFCFIPVIPFSLKPYKELGCSTCHFWQDINYRPDVLQQMSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQG8</accession>
    <name>W6ZQG8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar protein 56</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_1576</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683723.1">
        <property type="nucleotide sequence ID" value="XM_007685533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQG8"/>
    <dbReference type="STRING" id="930090.W6ZQG8"/>
    <dbReference type="GeneID" id="19119894"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1576"/>
    <dbReference type="eggNOG" id="KOG2573">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015495_5_2_1"/>
    <dbReference type="OrthoDB" id="6780543at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000452">
        <property type="term" value="P:snoRNA guided rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000001">
        <property type="entry name" value="Nucleolar protein 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000004">
        <property type="entry name" value="Nucleolar protein 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="7">
        <location>
            <begin position="300"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="465"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="518" mass="56585" checksum="B0FD382338853F6F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZR90</accession>
    <name>W6ZR90_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycoside hydrolase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_25729</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687278.1">
        <property type="nucleotide sequence ID" value="XM_007689088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZR90"/>
    <dbReference type="STRING" id="930090.W6ZR90"/>
    <dbReference type="GeneID" id="19120811"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25729"/>
    <dbReference type="eggNOG" id="KOG2230">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005015_2_4_1"/>
    <dbReference type="OrthoDB" id="408532at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043534">
        <property type="entry name" value="EBDG/EBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041351">
        <property type="entry name" value="Ig_GlcNase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536">
        <property type="entry name" value="MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536:SF1">
        <property type="entry name" value="MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18368">
        <property type="entry name" value="Ig_GlcNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889999" evidence="4">
        <location>
            <begin position="17"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="7">
        <location>
            <begin position="46"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="5">
        <location>
            <begin position="202"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Exo-beta-D-glucosaminidase Ig-fold" evidence="6">
        <location>
            <begin position="771"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="884" mass="98821" checksum="0A04FE562A49A8B5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRR9</accession>
    <name>W6ZRR9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_25599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687094.1">
        <property type="nucleotide sequence ID" value="XM_007688904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRR9"/>
    <dbReference type="GeneID" id="19120791"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25599"/>
    <dbReference type="HOGENOM" id="CLU_2049276_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="120" mass="12828" checksum="EB091EE9EA37BD86" modified="2014-04-16" version="1">MRTTLDTYTQQNTIPLLFMATNRNACQPGDLVSVDASPRSGLRSGVGPSPPHIASFPAVGNGQNRYLAAGFLRPAEILPAIPLMLAMRNLPSRVLHSQQSLAIPDPSYAFIVSTVGVSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZT25</accession>
    <name>W6ZT25_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="11">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_35589</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="11"/>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686638.1">
        <property type="nucleotide sequence ID" value="XM_007688448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZT25"/>
    <dbReference type="STRING" id="930090.W6ZT25"/>
    <dbReference type="GeneID" id="19122819"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35589"/>
    <dbReference type="eggNOG" id="KOG0352">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001103_9_3_1"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18794">
        <property type="entry name" value="SF2_C_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001834">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF153">
        <property type="entry name" value="RECQ-LIKE DNA HELICASE BLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="33"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="250"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC46861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="485" mass="55042" checksum="AD566D8C70F1B862" modified="2014-04-16" version="1">MPGPRKRPYSNIDFTLRKVFKKAAFRPPQREVVLATLEGQDVFVQAATSFGKSLCYQLPAVVDFGITIVISPLLALMNNQVASLRNANIRVETINSTTPTEDRKRILADLQCGHPLTRLLYVTPEFCQGDHFRKILRVIHSQRELARIAVDEAHCVSEWGHDFRPSFQQLSFFKTEFPDVPVICLTATATARVRDDIINTLALDPKKLAMFRMSSSRPNLHYEVRFKSDEEDHYDDFLSMLKGIYARRAERPERVTQLASQNQRTDNVPGIIYTLFRKDCESLAERLRSDGIGAKPYHAGLSVSERADALSGWIANKLGYDIIVATTAFGMGIDKENVRFVVHWQIPKSFEGFYQEAGRAGRDGKASLCILYYGREDRDRAANMMARDAARQPSKSGGPDAQQQQLMNRARSLQTLVGYCEATDKCRHKIIAKYFADEVPAPCDFACDWCKDAEALVRRKERGLASEEWCSTQRAEGRYDVDEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZT88</accession>
    <name>W6ZT88_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carbohydrate-binding module family 18 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_25135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686546.1">
        <property type="nucleotide sequence ID" value="XM_007688356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZT88"/>
    <dbReference type="GeneID" id="19120709"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25135"/>
    <dbReference type="eggNOG" id="ENOG502S5QM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044725_0_0_1"/>
    <dbReference type="OrthoDB" id="2426396at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39599:SF1">
        <property type="entry name" value="GPI-ANCHORED PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39599">
        <property type="entry name" value="GPI-ANCHORED PROTEIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890201" description="Carbohydrate-binding module family 18 protein" evidence="3">
        <location>
            <begin position="26"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="466" mass="47543" checksum="52A6C7CD73BB95A7" modified="2014-04-16" version="1">MHLNHLLSLPPAIIALCATSSVVAAQADSHQQQWPHNVPKHLKYFPEDEAHAKRGLRVAQRLQHEKPIGVKKMSLDEGEMFMLDNWIFASESQQQSRRSDLDNLGNLTVQAASPLRPLAQSGWLARMHIRDVLLKRQFKCPEGTNSCESIGAPDVCCGTGSDCINTSGNSDAGNVGCCPKGQTCAGNVSCDTAGGYSSCPGSSNGGCCMPGFRCQGIGCVLEATSTTFIPPSSTSTTAAPPAPTSTAAQTSTTPTPSSTTPPPVTSSSSRTAYTCSTGWFSCPASLGGGCCQTGRTCATGASCIGDPPTTSTRAPDAPIRPTSGTTTAAQATSAEVCPQGFYVCSAYYPSGCCRVGRDCQTTGSSCVLPTGTVVDTNGVTVVAPTTSAGSCPSAWYSCAASAGGNCCPQGYACGEQQCTATASGQAGTTEKVVPSSSSSQASFVAVVPIAVSFFVAGAIGVAMVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTL4</accession>
    <name>W6ZTL4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein PNG1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein png1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_3927</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglutaminase-like superfamily. PNGase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686387.1">
        <property type="nucleotide sequence ID" value="XM_007688197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTL4"/>
    <dbReference type="STRING" id="930090.W6ZTL4"/>
    <dbReference type="GeneID" id="19123647"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3927"/>
    <dbReference type="eggNOG" id="KOG0909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031058_1_0_1"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.620.30:FF:000004">
        <property type="entry name" value="Peptidase (PNG1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000011">
        <property type="entry name" value="peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF19">
        <property type="entry name" value="PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Transglutaminase-like" evidence="7">
        <location>
            <begin position="230"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00071430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="441" mass="50247" checksum="EE6D0488B5A0D425" modified="2014-04-16" version="1">MDHNTRAPRAATNAMDTDRLAAELTEQFRHVLSTKRINDLTSRSSQSRSSSPAPRDFGSPQPPPSQAAPPAYSSIKNIPLVPEPPRDARSLRFKNMLHSLSNMPVRWENPGLLDEALRVIPLEQIYNEAEEESQILQAEAESMGAGKKAAWGYQDCVVRALLRWFKRSFFSWVNNPPCSRCYSPTVAMGITPPLPDEQARGASQVEAYRCSNDSCRNYERFPRYNDAFVLLQTRRGRCGEWANCFSMLCRAVGSRVRWVWNAEDHVWTEVYSVHRKRWVHVDACEEAWDKPRLYTDGWGKKLSYCIAFSADGAMDVTRRYVRDAKHAAERNRAPEAVLLYIMDEIRATRRANMSKQDKFRLQGEDIREAKELRAGVISSIAQAVCKLRPEDIINGQVTRRLDADAQKALEGRLSGNSAWIRARGEGGQQQNQQDPRNQHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTX8</accession>
    <name>W6ZTX8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_35311</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686329.1">
        <property type="nucleotide sequence ID" value="XM_007688139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTX8"/>
    <dbReference type="STRING" id="930090.W6ZTX8"/>
    <dbReference type="GeneID" id="19122754"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35311"/>
    <dbReference type="eggNOG" id="KOG3996">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048602_0_0_1"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF3">
        <property type="entry name" value="HOLOCYTOCHROME-C SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="311"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC47161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="340" mass="38360" checksum="768D2A30EFDD1AD3" modified="2014-04-16" version="1">MGWFWADTAPSAPAARNAPHPMPRGSMEPPPECPMHKKATPPVVAEKTSQSACPYVPPEKSSSGPSEPPKTGLLSRLNPLNNMFADLSNERADKQVHNLPLERETSTIPKGDGSLWEYPSPQQMYNAMLRKGYTDTDITAVESMVGVHNFLNEGAWAEIMGWERRFSRGLAEGYQICKKGEDVANFLLGTADDPFDTTTWDDKDIPPPKLLRFTGRPTEPTPKSQILQWLGYVMPEQFGTNPPFDRHDWFVERCNEQGCKEIRYVIDYYEGAPEPTGEPVFYLDVRPAVDGPTSAAERLIRSGTDIWWRASGGVTRELKRLEKAKREKEEEWAAKSRQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU38</accession>
    <name>W6ZU38_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COP9 signalosome complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_31624</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682348.1">
        <property type="nucleotide sequence ID" value="XM_007684158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZU38"/>
    <dbReference type="STRING" id="930090.W6ZU38"/>
    <dbReference type="MEROPS" id="M67.A01"/>
    <dbReference type="GeneID" id="19121911"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31624"/>
    <dbReference type="eggNOG" id="KOG1554">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053034_0_2_1"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019784">
        <property type="term" value="F:deNEDDylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000003">
        <property type="entry name" value="COP9 signalosome complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040961">
        <property type="entry name" value="CSN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18323">
        <property type="entry name" value="CSN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="10">
        <location>
            <begin position="51"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC51064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="353" mass="39198" checksum="4A4F9B2486356699" modified="2014-04-16" version="1">MGTALKTWELENSIKLVDPSKDALYNYSPAAQRAINEAHPWRTDPNYFTSVRISAIALLKMVMHARSGGSLEVMGLMLGKIEAHTFVVTDAFRLPVEGTETRVNAQDEANEYMVEFLQRAREQGQMENAVGWYHSHPGYGCWLSGIDVNTQKTQQQFQDPFCAIVIDPDRTISAGKVEIGAFRTYSTEYVENQQKTGGSKVSGGTDSDGFETIPLGKIEDFGAHASHYYSLEVSHYKSSLDAKLLEALWNKYWVQTLSSSPLISNREYGTKQISDLARKMQQESHNSSRFKGGQGYSNSLEVKNQLTKLGAVGSKIAREEDMGLLAAQVKDKVFSLPSEGEVKSPDVVEMETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W7A022</accession>
    <name>W7A022_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_84794</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684089.1">
        <property type="nucleotide sequence ID" value="XM_007685899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A022"/>
    <dbReference type="GeneID" id="19126534"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84794"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC49331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="28336" checksum="F6D5E718E177E829" modified="2014-04-16" version="1">MASSSTSEPVKKVQLEGKVIAITGANRGIGLGIADCCLTNGARAVYSLDIGTPDSDFAALSSKYPNQLFALEADVTKEESIQAAIDKVLAEAGALHGMVCNAGRTKHKPALEFTTEEIDQLWGVNLYGSFYSARCAARAFIKQGVKGSIVFTASMASYRPNKRVPSAPYGASKAGIRNMTHTLAMEWAQYNIRVNSVSPGLVKTAMTYWVEQQPDWEQQLKYYGGMPRLAAVEELGGAYVYLLSDAASYTTSIDIPVNGVIGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0X3</accession>
    <name>W7A0X3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Vacuolar fusion protein MON1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_32917</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">In complex with CCZ1, is required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis. The MON1-CCZ1 complex acts at the fusion of vesicles with the vacuole, through its regulation of the SNARE complex during the coordinated priming and docking stages of fusion, and particularly at the stage of tethering/docking.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endosome</location>
            <location evidence="4">Multivesicular body membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 4">Prevacuolar compartment membrane</location>
            <topology evidence="1 4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Vacuole membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MON1/SAND family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683760.1">
        <property type="nucleotide sequence ID" value="XM_007685570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0X3"/>
    <dbReference type="STRING" id="930090.W7A0X3"/>
    <dbReference type="GeneID" id="19122206"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32917"/>
    <dbReference type="eggNOG" id="KOG0997">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014574_5_0_1"/>
    <dbReference type="OrthoDB" id="272411at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035658">
        <property type="term" value="C:Mon1-Ccz1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032585">
        <property type="term" value="C:multivesicular body membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043972">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043971">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043970">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004353">
        <property type="entry name" value="Mon1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027">
        <property type="entry name" value="SAND PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027:SF7">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN MON1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19036">
        <property type="entry name" value="Fuz_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19037">
        <property type="entry name" value="Fuz_longin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19038">
        <property type="entry name" value="Fuz_longin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01546">
        <property type="entry name" value="YEAST73DUF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="FUZ/MON1/HPS1 first Longin" evidence="6">
        <location>
            <begin position="243"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 second Longin" evidence="7">
        <location>
            <begin position="405"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 third Longin" evidence="8">
        <location>
            <begin position="553"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC49696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="663" mass="72638" checksum="8313E69212E219BF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W7A132</accession>
    <name>W7A132_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_77260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683659.1">
        <property type="nucleotide sequence ID" value="XM_007685469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A132"/>
    <dbReference type="STRING" id="930090.W7A132"/>
    <dbReference type="GeneID" id="19125373"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_77260"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_12_2_1"/>
    <dbReference type="OrthoDB" id="2431938at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="10"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="427" mass="48113" checksum="910ABCD32075D250" modified="2014-04-16" version="1" fragment="single">MGDFEKSHDFKVVIVGGSVAGLVLAHSLHKAGIDYIVLEGRDHIDPQIGASIGLFSNGSRILDQLGVFESILECTEPLKWYDMLTGQGDLVRRDDSLQLIEARTGYPVTFLERRQVLQKLHQLSPDQSKILTGKKVVSVRTLPDGVEVNCADGSIFTGDIVAGADGVHSRIRREMWRHAKSDDALKHLKDDEKAMFADYRCLYGMSSPVPGLRETSIYRTFNKDWSFLVVVGKHECCFWFVFEKLSRTHRLPDLPRYTESDQDEFVKPFMNRHVSQDVNFGALWHRKIAATLAALEEAQYNHWTYGRFVCLGDSIHKMTPNIGQGGNWAIESAAALTNKLRAMMSTTQRPSFGQICDTLSDYEQSRQIRTKEVCAMAGFATRLEAFDKFWHKPMALYVVPRAGDMLVDVHCQSVAGAHMLDFLPPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1A3</accession>
    <name>W7A1A3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_32848</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683649.1">
        <property type="nucleotide sequence ID" value="XM_007685459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A1A3"/>
    <dbReference type="STRING" id="930090.W7A1A3"/>
    <dbReference type="GeneID" id="19122189"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32848"/>
    <dbReference type="eggNOG" id="KOG0682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_33_0_1"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000003">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF4">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="39"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="481"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="492"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="522" mass="56645" checksum="D945373B542F6385" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1Y3</accession>
    <name>W7A1Y3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683386.1">
        <property type="nucleotide sequence ID" value="XM_007685196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A1Y3"/>
    <dbReference type="GeneID" id="19120237"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22373"/>
    <dbReference type="eggNOG" id="ENOG502T607">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1129563_0_0_1"/>
    <dbReference type="OrthoDB" id="5089392at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="242" mass="27425" checksum="5CADD1CE6B21683B" modified="2014-04-16" version="1">MPYYPKTTSIYSTSSSSEEEHYYIPSRDQRHNYNWDTNQPHTLIPQLNTATTFSTKSPTSLPMTDSSHHHQPIDARALHSRLAVITSNNNNSNETTTDHGSPHRRLRPSLDSTITTNNTLPFTKSSTISTFDSHTSTTSSRLHASPSSRLHPETVGIAPGDFSKPRVPRRSRRYTMESSTSSGSARREREEPAQFKYYGRHGNQWLFNDFSVSGAVAKGFRRVFRGKGEEGKGDWYEDREGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1Z0</accession>
    <name>W7A1Z0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.256</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Asparagine-linked glycosylation protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_32615</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the third and last glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(2)Man(9)GlcNAc(2)-PP-Dol to produce Glc(3)Man(9)GlcNAc(2)-PP-Dol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = a alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29543"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="Rhea" id="RHEA-COMP:19512"/>
            <dbReference type="Rhea" id="RHEA-COMP:19522"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:132522"/>
            <dbReference type="ChEBI" id="CHEBI:132523"/>
            <dbReference type="EC" id="2.4.1.256"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:29544"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ALG10 glucosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.256" evidence="4"/>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683413.1">
        <property type="nucleotide sequence ID" value="XM_007685223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A1Z0"/>
    <dbReference type="STRING" id="930090.W7A1Z0"/>
    <dbReference type="GeneID" id="19122143"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32615"/>
    <dbReference type="eggNOG" id="KOG2642">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017053_0_0_1"/>
    <dbReference type="OrthoDB" id="4769at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106073">
        <property type="term" value="F:dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016900">
        <property type="entry name" value="Alg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989">
        <property type="entry name" value="ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989:SF10">
        <property type="entry name" value="DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04922">
        <property type="entry name" value="DIE2_ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028810">
        <property type="entry name" value="Alpha1_2_glucosyltferase_Alg10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="357"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC50046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="553" mass="61892" checksum="46D40AC1C5564233" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YL63</accession>
    <name>W6YL63_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964220">
        <property type="protein sequence ID" value="EUC39937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YL63"/>
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    <dbReference type="HOGENOM" id="CLU_3055851_0_0_1"/>
    <dbReference type="OrthoDB" id="3683655at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="55" mass="5967" checksum="20451E409D2DFB84" modified="2014-04-16" version="1" fragment="single">TPSSLSYSPATTSPDDYPPQCEAHSSICSQLRTSPQPPHTLLTPEKRVCLTVIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLA7</accession>
    <name>W6YLA7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_10046</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964213">
        <property type="protein sequence ID" value="EUC39982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693494.1">
        <property type="nucleotide sequence ID" value="XM_007695304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLA7"/>
    <dbReference type="STRING" id="930090.W6YLA7"/>
    <dbReference type="GeneID" id="19117679"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10046"/>
    <dbReference type="eggNOG" id="ENOG502SMU6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041307_1_1_1"/>
    <dbReference type="OrthoDB" id="2830640at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC39982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="397" mass="45875" checksum="1FF2625E17C49B44" modified="2014-04-16" version="1">MPNSRGPPMNTIDLIRLSAGCWNSHTERLDHCLRDQGDPEKQYLFIQDDPFSYSGSGKLQPELIQYFQIPQYLLANIYRRSNGFFAFKESQGQNGQLESCYMWFRVEIKTVDANDGMRYHWHEMTFCYRWDSKSCSILCLGVDAAFKSCLKEKLRQMWPGIQGSQPGCLLVPLIEVLVVTYDQSVWSMRDTVRQAEKNRTHSTRHTTKSDLLYEATRHAIHSSETLDVAINTLSSIQHQIASQSKRSLPVPYDVQDLADLINNHLGFQVRMLRNLHLRAQSNKARVQNENVYAYNMATQRDSEIMKGLGAAAKEDSGVMRTIAVVTMFFLPPTFISAVFSMSFFNYTPPQDGAAGKWSVSDRFWIYWAFAIPLTALTLGIWALRQRWMCWRYWFDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMP8</accession>
    <name>W6YMP8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964155">
        <property type="protein sequence ID" value="EUC40557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692914.1">
        <property type="nucleotide sequence ID" value="XM_007694724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMP8"/>
    <dbReference type="GeneID" id="19119258"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108505"/>
    <dbReference type="HOGENOM" id="CLU_2236110_0_0_1"/>
    <dbReference type="OrthoDB" id="3692731at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="105" mass="10551" checksum="2705C0D060FDCB40" modified="2014-04-16" version="1">MICALPILNLGCTTGEPRYGNGLGGSGDVGRPVQWDPTRGPLAPARDDSTPNGNIQVGNGAAFRSSSSSASSNSSSSSNSSSSSSSCLCRACDDEDSQSALLHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YN39</accession>
    <name>W6YN39_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_9465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964145">
        <property type="protein sequence ID" value="EUC40702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YN39"/>
    <dbReference type="GeneID" id="19128490"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9465"/>
    <dbReference type="eggNOG" id="ENOG502SVG3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122923_1_0_1"/>
    <dbReference type="OrthoDB" id="5410040at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40020">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40020:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004885897" evidence="2">
        <location>
            <begin position="29"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="136" mass="15450" checksum="27DF304DC7C16073" modified="2014-04-16" version="1">MPPHLHPRSRMTTSLFTSTLMISFLVVAAPHILPCPVDPRTLADSADPTGENRMRRRRRISDGEVNEDNLSEERRRRRQLIEEKLAAKRECPVPKPGGLIGQVLGVHEEDQKEQQPSIVQRVEKAICRPWGKTGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YP68</accession>
    <name>W6YP68_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_10445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964416">
        <property type="protein sequence ID" value="EUC39470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007694011.1">
        <property type="nucleotide sequence ID" value="XM_007695821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YP68"/>
    <dbReference type="GeneID" id="19118506"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10445"/>
    <dbReference type="HOGENOM" id="CLU_1669069_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886073" evidence="1">
        <location>
            <begin position="25"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="158" mass="17245" checksum="08536D99F37357C3" modified="2014-04-16" version="1">MLLLNNFVNIITLIGAMMSFQVQGLAVDLPTALSKRQGQCLSRRRAIAAAGYLGTWTIDVSEVGNGIFHRPVPYPDIGLVTDIASAEADTMRFRWQGASTMPRNTNYFLVPGDYLRENGVPASSPNIVHLTTHSECDVTYDRGAGVTAVSVKVYRVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YP89</accession>
    <name>W6YP89_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase Rpb4/RPC9 core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_111415</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964387">
        <property type="protein sequence ID" value="EUC39495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693986.1">
        <property type="nucleotide sequence ID" value="XM_007695796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YP89"/>
    <dbReference type="STRING" id="930090.W6YP89"/>
    <dbReference type="GeneID" id="19119766"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111415"/>
    <dbReference type="eggNOG" id="KOG2351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110332_0_0_1"/>
    <dbReference type="OrthoDB" id="2186918at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030880">
        <property type="term" value="C:RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="5">
        <location>
            <begin position="44"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC39495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="177" mass="19942" checksum="3854927F178EB7A4" modified="2014-04-16" version="1">MEADGEHNAPQRPEPPVFKAPRLVSRPKPPVQQEEEMGSEIKLGDFEDVHALSVSEARAVVTAVHEARKKKDPENNPLRDRIYNDSITITQFLDYLDNFARYKEEDSLHSIAALFDAHPEISVVEKALLGTLTPDTAEEATTLIPSLKMDEDELQLILDELNKMRELEKINNTVLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQT6</accession>
    <name>W6YQT6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_10126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964232">
        <property type="protein sequence ID" value="EUC39873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693603.1">
        <property type="nucleotide sequence ID" value="XM_007695413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQT6"/>
    <dbReference type="GeneID" id="19117842"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10126"/>
    <dbReference type="eggNOG" id="ENOG502SYXF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180923_0_0_1"/>
    <dbReference type="OrthoDB" id="2279190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="97" mass="9991" checksum="8A71EF24429D8A32" modified="2014-04-16" version="1">MADSTTKDLTGTAGNATGGRGLPEVGELMGSVSNPGNKTKGKKGKGKGNDDGEDEEGFGLDNNKDVKGSLKIHIKLDLEADIRIIARVKGDIAIGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR61</accession>
    <name>W6YR61_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CWH43-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_29346</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PGAP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964079">
        <property type="protein sequence ID" value="EUC41942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691521.1">
        <property type="nucleotide sequence ID" value="XM_007693331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR61"/>
    <dbReference type="GeneID" id="19121489"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29346"/>
    <dbReference type="eggNOG" id="ENOG502RZQS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050573_0_0_1"/>
    <dbReference type="OrthoDB" id="10032492at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039545">
        <property type="entry name" value="PGAP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12892">
        <property type="entry name" value="FGF RECEPTOR ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12892:SF11">
        <property type="entry name" value="POST-GPI ATTACHMENT TO PROTEINS FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="10">
        <location>
            <begin position="6"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="230"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC41942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="265" mass="30351" checksum="7C003B4A9A208AF5" modified="2014-04-16" version="1">MLGLSYWIVPIFSAVVWTGMLIAMMVYWASTGKPIYSTMSQGQHIPYISDIGADKLKPMFIAMSVVTVVTFDCAFIFERWLRHTNKLRPNTSNWQKLYSVCATVAAVAGAAGLILLTIFDCKRHNTLHNIFLVVFIASYIISAIFICWEYQRLGVHYREESILRISFWIKLFFIIFEVCLVIAFGVCSKTDRWNAAAVLEWIIAFTYCFYVASFFIDFLPARRTKHHQSKETEVQMLEEGGQTHSTTDNARMGAPYPTPLSSRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRD5</accession>
    <name>W6YRD5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_30915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964200">
        <property type="protein sequence ID" value="EUC40078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693395.1">
        <property type="nucleotide sequence ID" value="XM_007695205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRD5"/>
    <dbReference type="GeneID" id="19121768"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30915"/>
    <dbReference type="HOGENOM" id="CLU_1594234_0_0_1"/>
    <dbReference type="OrthoDB" id="10567563at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="167" mass="18875" checksum="000AE7941FB30162" modified="2014-04-16" version="1">MKHIRKKHIEKTRTKIENKPVNPELIAKHPSATNTHSSTTKDNSTSVSRARPVILRSDDPKKVKKLQNSMERGDVWYILDHHRARKRSKGSADFQGIHPLIIPKAVPSTQIPENQKAWRCNTNLLIEAGASFDSYLHHSFKTCPLCETSQNAKGKEGKGKEGECYPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRN3</accession>
    <name>W6YRN3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_9928</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964193">
        <property type="protein sequence ID" value="EUC40148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693340.1">
        <property type="nucleotide sequence ID" value="XM_007695150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRN3"/>
    <dbReference type="STRING" id="930090.W6YRN3"/>
    <dbReference type="GeneID" id="19129436"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9928"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007199_0_0_1"/>
    <dbReference type="OrthoDB" id="942095at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14003">
        <property type="entry name" value="STKc_AMPK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000434">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="41"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="355"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="512"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="719"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="403"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="533"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="546"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="627"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="726"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="751"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="767"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="804"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="162"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC40148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="826" mass="91305" checksum="DDF00A84D0EFAE9E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS11</accession>
    <name>W6YS11_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964167">
        <property type="protein sequence ID" value="EUC40415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693059.1">
        <property type="nucleotide sequence ID" value="XM_007694869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS11"/>
    <dbReference type="GeneID" id="19121709"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30638"/>
    <dbReference type="eggNOG" id="ENOG502S0V0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008442_1_0_1"/>
    <dbReference type="OrthoDB" id="4088568at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="640"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="680"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="704"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="763" mass="83168" checksum="0DD3A92DCD1EEAC1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT18</accession>
    <name>W6YT18_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_108040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964143">
        <property type="protein sequence ID" value="EUC40725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692749.1">
        <property type="nucleotide sequence ID" value="XM_007694559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT18"/>
    <dbReference type="STRING" id="930090.W6YT18"/>
    <dbReference type="GeneID" id="19119173"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108040"/>
    <dbReference type="eggNOG" id="ENOG502SM0U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103010_1_0_1"/>
    <dbReference type="OrthoDB" id="5336600at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF4">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="24857" checksum="DBAEAABF47FBCC20" modified="2014-04-16" version="1">MSAKPIALILGAGPNAGTAIASSLSSLGYRIATASRSASTSLPTSDTLALTADFTNPSSIPPLFTRIHTDLHAYPSVVVYNAATLTPPLDAGVVTSVPVDKFAADLNVNVVSPYVAAQEAVKGWKKMGQEEGGEKTFIFTGNMLNRTILPVDALVTLGVGKSASAYWVGLADEIHKGEGYRFFYTDQRQPDGSPMGNVVDGPAHGEFYAQLVQRTNEVPWLATFVKGKGHVKFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT41</accession>
    <name>W6YT41_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rhamnogalacturonan endolyase</fullName>
            <ecNumber evidence="4">4.2.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_28756</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1-&gt;4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end.</text>
            <dbReference type="EC" id="4.2.2.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide lyase 4 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.23" evidence="4"/>
    <dbReference type="EMBL" id="KI964054">
        <property type="protein sequence ID" value="EUC42627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690832.1">
        <property type="nucleotide sequence ID" value="XM_007692642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT41"/>
    <dbReference type="STRING" id="930090.W6YT41"/>
    <dbReference type="GeneID" id="19121369"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28756"/>
    <dbReference type="eggNOG" id="ENOG502QQM5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016624_0_0_1"/>
    <dbReference type="OrthoDB" id="2130367at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102210">
        <property type="term" value="F:rhamnogalacturonan endolyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10316">
        <property type="entry name" value="RGL4_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10320">
        <property type="entry name" value="RGL4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1120">
        <property type="entry name" value="Carboxypeptidase-like, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051850">
        <property type="entry name" value="Polysacch_Lyase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029413">
        <property type="entry name" value="RG-lyase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029411">
        <property type="entry name" value="RG-lyase_III"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32018:SF9">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32018">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14683">
        <property type="entry name" value="CBM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14686">
        <property type="entry name" value="fn3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886726" description="rhamnogalacturonan endolyase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase" evidence="13">
        <location>
            <begin position="353"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase" evidence="12">
        <location>
            <begin position="442"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC42627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="664" mass="73260" checksum="86466DD849D0A2D0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTS1</accession>
    <name>W6YTS1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_39147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964047">
        <property type="protein sequence ID" value="EUC42852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTS1"/>
    <dbReference type="GeneID" id="19123620"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39147"/>
    <dbReference type="HOGENOM" id="CLU_2996217_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="57" mass="6385" checksum="1201D9010B69AE87" modified="2014-04-16" version="1">MITIRFLSTRPAPVSFVSGLLARHALLRLHAIFALAARLFCHVDPRARTLLIDQICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUC1</accession>
    <name>W6YUC1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_106969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964118">
        <property type="protein sequence ID" value="EUC41123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692348.1">
        <property type="nucleotide sequence ID" value="XM_007694158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUC1"/>
    <dbReference type="GeneID" id="19118954"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106969"/>
    <dbReference type="eggNOG" id="ENOG502T5PR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158152_0_0_1"/>
    <dbReference type="OrthoDB" id="3787314at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889424" evidence="1">
        <location>
            <begin position="21"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="131" mass="12736" checksum="BAFFD1AF5997BA30" modified="2014-04-16" version="1">MPSFQQIPLALCALVATAVATTSSDTISYDATVYITSTITRVNTVTASSSPTGAPVNQTSTIIASHPTAAPSFSSFNAGNATGVAPTAAPSASTATLPSASAPAAFPGAASSLTANVYLAVVAAGLGYLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUG3</accession>
    <name>W6YUG3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_106869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964116">
        <property type="protein sequence ID" value="EUC41165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692308.1">
        <property type="nucleotide sequence ID" value="XM_007694118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUG3"/>
    <dbReference type="GeneID" id="19118936"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106869"/>
    <dbReference type="HOGENOM" id="CLU_2928854_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="61" mass="7233" checksum="EB9759C0E2A59B4D" modified="2014-04-16" version="1" fragment="single">MQVSCYREDVFYRDCAGALDWKSGRDVLRRRAVTKLFWTPVRSVSFPNIRSFAQLAIQHQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVG4</accession>
    <name>W6YVG4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase A22B, signal peptide peptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_100955</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964030">
        <property type="protein sequence ID" value="EUC43417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690095.1">
        <property type="nucleotide sequence ID" value="XM_007691905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVG4"/>
    <dbReference type="STRING" id="930090.W6YVG4"/>
    <dbReference type="GeneID" id="19117772"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100955"/>
    <dbReference type="eggNOG" id="KOG2443">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023799_1_0_1"/>
    <dbReference type="OrthoDB" id="29661at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF23">
        <property type="entry name" value="MINOR HISTOCOMPATIBILITY ANTIGEN H13"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
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            <begin position="30"/>
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        </location>
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        </source>
    </evidence>
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        </source>
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        <source>
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        </source>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX49</accession>
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        <submittedName>
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        </submittedName>
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        <name evidence="2" type="ORF">COCMIDRAFT_109641</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
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        <location>
            <begin position="1"/>
            <end position="21"/>
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    </feature>
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            <end position="488"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="520"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40099.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="540" mass="60890" checksum="28F349F579707F05" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <recommendedName>
            <fullName evidence="3">Nucleolar protein 58</fullName>
        </recommendedName>
    </protein>
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        <name evidence="11" type="ORF">COCMIDRAFT_99270</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
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                <person name="Lowry S."/>
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                <person name="Han J."/>
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            <strain evidence="11 12">ATCC 44560</strain>
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        <text evidence="8">Required for pre-18S rRNA processing. May bind microtubules.</text>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:snoRNA guided rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nop_C"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Nop" evidence="10">
        <location>
            <begin position="280"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
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            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="441"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
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            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="522"/>
            <end position="556"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="565" mass="60869" checksum="731CFFCA9FDEA855" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXC2</accession>
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        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_104294</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964071">
        <property type="protein sequence ID" value="EUC42165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691337.1">
        <property type="nucleotide sequence ID" value="XM_007693147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXC2"/>
    <dbReference type="GeneID" id="19118481"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104294"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF45">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="13"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="512" mass="56370" checksum="B841D91685D862C5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXG0</accession>
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        <recommendedName>
            <fullName evidence="7">Cell division control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_8182</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDC6/cdc18 family.</text>
    </comment>
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        <property type="nucleotide sequence ID" value="XM_007693067.1"/>
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    <dbReference type="HOGENOM" id="CLU_012774_2_0_1"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
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    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="WHD_Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001767">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="9">
        <location>
            <begin position="206"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6/ORC1-like ATPase lid" evidence="11">
        <location>
            <begin position="349"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6 C-terminal" evidence="10">
        <location>
            <begin position="498"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC42220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="646" mass="70247" checksum="2FDA9387A50FEBA4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXP4</accession>
    <name>W6YXP4_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964065">
        <property type="protein sequence ID" value="EUC42318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691161.1">
        <property type="nucleotide sequence ID" value="XM_007692971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXP4"/>
    <dbReference type="GeneID" id="19118377"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103788"/>
    <dbReference type="eggNOG" id="ENOG502SW7X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_212308_0_0_1"/>
    <dbReference type="OrthoDB" id="4596934at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="53" mass="5870" checksum="F7DDCB9F2187FF1C" modified="2014-04-16" version="1">MARPSCSHSFKLIKSDTTLVVWTCNLCHSGPFTSIYECDQCKLKTCQPCASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXU2</accession>
    <name>W6YXU2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_103639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964063">
        <property type="protein sequence ID" value="EUC42390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691111.1">
        <property type="nucleotide sequence ID" value="XM_007692921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXU2"/>
    <dbReference type="GeneID" id="19118347"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103639"/>
    <dbReference type="eggNOG" id="ENOG502QPXG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027163_0_0_1"/>
    <dbReference type="OrthoDB" id="2589563at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037737">
        <property type="entry name" value="Srf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36819">
        <property type="entry name" value="REGULATOR OF PHOSPHOLIPASE D SRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36819:SF1">
        <property type="entry name" value="REGULATOR OF PHOSPHOLIPASE D SRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="423" mass="46597" checksum="DABA0C447D18A637" modified="2014-04-16" version="1">MTSSSPSPSSSAASTTTNTPTAPAPAQPNRLLPSPIPPPSSSSLHSHPHSFQRPQSRISAVSGVSKDSHDGGPARKSQSYSISSTPRTLASSNRSLTASAENRERQRAVRSLPPWVQSAEDEDDADATSFLLPRTPTTVRHATHNFCPTPKSNVPGRKFDHVREGAPVTLGTPVSDSAPKWKQFTQGSNLDRPISSRGQIVDDDWMKENMPDLEQKWEPIGESAPKEQIKGFWLFTSEKRRHAFVRFHNTVMNHPMVPAVIRAFVLVFSTLALSLAASIYRHSDNNGCSNNSSTWMAILVDIVAIIYTLYITYDEYTSKPLGLRSHNAKMSLIFLDLAFIVFESANLSLAFQALTDEKWACVESGSENSCPYRMSICERQKGLTATLFIALIAWIATFAISTLRYMICLAIITIVPFITNMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYC1</accession>
    <name>W6YYC1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Histone acetyltransferase</fullName>
            <ecNumber evidence="3 13">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_108496</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac. The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination. Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins. In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 13"/>
    <dbReference type="EMBL" id="KI964155">
        <property type="protein sequence ID" value="EUC40559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692916.1">
        <property type="nucleotide sequence ID" value="XM_007694726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYC1"/>
    <dbReference type="STRING" id="930090.W6YYC1"/>
    <dbReference type="GeneID" id="19119256"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108496"/>
    <dbReference type="eggNOG" id="KOG2747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005327_1_2_1"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990467">
        <property type="term" value="C:NuA3a histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.60:FF:000001">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000001">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF161">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16866">
        <property type="entry name" value="PHD_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="15">
        <location>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18647">
        <property type="entry name" value="Fungal_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886421" evidence="1">
        <location>
            <begin position="21"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="668" mass="75613" checksum="EE37F2F455E7B749" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZD4</accession>
    <name>W6YZD4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_39066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964044">
        <property type="protein sequence ID" value="EUC42953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690533.1">
        <property type="nucleotide sequence ID" value="XM_007692343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZD4"/>
    <dbReference type="GeneID" id="19123608"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39066"/>
    <dbReference type="HOGENOM" id="CLU_1250466_0_0_1"/>
    <dbReference type="OrthoDB" id="10333758at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="235" mass="26004" checksum="6C68471C44301E2D" modified="2014-04-16" version="1">MAEFVADRMGINGKQQQQQQQRPLPRTGAPLWALLDWIHPGAELHWEGRVSMATCGWRAVSCKIGGCRMDNDARHQKAAICCRRAIYTGPVVLMTQLDNCSTLFVTPCTRVDGHGRPWMMMMMATVLMSRSRSRGRVNVGELRGKFGWPCLSPRRARSRAHVFAHCVISNIAAIHTLPPFHTRLAWISITTLVARPSRCTLSDTAVSLARGPNLLALAIYCDTATPAPAHQISHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZZ1</accession>
    <name>W6YZZ1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_96881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688546.1">
        <property type="nucleotide sequence ID" value="XM_007690356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZZ1"/>
    <dbReference type="GeneID" id="19128936"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96881"/>
    <dbReference type="HOGENOM" id="CLU_3111824_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="51" mass="6023" checksum="5D697786982028B8" modified="2014-04-16" version="1" fragment="single">LIAEVLGFLSWLSLQHYTRLISNQVIYLGVTKTKTTSCTICWRWHAHRVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0A7</accession>
    <name>W6Z0A7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_28168</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964032">
        <property type="protein sequence ID" value="EUC43330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690131.1">
        <property type="nucleotide sequence ID" value="XM_007691941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0A7"/>
    <dbReference type="GeneID" id="19121255"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28168"/>
    <dbReference type="eggNOG" id="KOG4629">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_581364_0_0_1"/>
    <dbReference type="OrthoDB" id="3692227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF1">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886305" description="EF-hand domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="187"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="470" mass="53137" checksum="8898ABB3A3E7E81B" modified="2014-04-16" version="1">MRTQVLFAMSLVAWGSSSVMCRISDSTCDERWIMVLRKVLLATIPAAAIFYAEDILMECIITHQAKRIYKKRNLDEIMRQNQFTTCTGPRLLASTSVTRLLSITVKFFEALFLRNRPDPNNEHNQSKRYILGKGSDKEFDRHGKPFLETFVEQRLPGEDMSFTQEFLKKKLDEGIGKVIDSGLLLMEKGFTAAEIMKMMDKDDSGVITRDEVAELLKELIMAMRDINKSVNGMRRAARSANAVVCFLLLFVVAIIYAGFFVKNLTSYLTPISITITGLSFALGGAVTEFITACQFVFSKQPYNVGDRVIIEEKELIVEKVCLLYTVFNRCSDCAVEQIAHKKICDAWITNLTRSKGLIIKEVASIADKMGIFTSDQLEAHEKDLVDFTNKETVRKSYLDAGGVKVSLHAEQQQLVANIKLNEIMVRHEKVLSRMRGQIRDWLERLVREGGGQVSVKVEPTTSIEPTIKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0K1</accession>
    <name>W6Z0K1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">agmatinase</fullName>
            <ecNumber evidence="4">3.5.3.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_101491</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>agmatine + H2O = urea + putrescine</text>
            <dbReference type="Rhea" id="RHEA:13929"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="3.5.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="5">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.11" evidence="4"/>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690275.1">
        <property type="nucleotide sequence ID" value="XM_007692085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0K1"/>
    <dbReference type="STRING" id="930090.W6Z0K1"/>
    <dbReference type="GeneID" id="19117877"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101491"/>
    <dbReference type="eggNOG" id="KOG2964">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_1_1_1"/>
    <dbReference type="OrthoDB" id="288726at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033389">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via agmatine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019627">
        <property type="term" value="P:urea metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11592">
        <property type="entry name" value="Agmatinase_PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000006">
        <property type="entry name" value="Agmatinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF30">
        <property type="entry name" value="AGMATINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886320" description="agmatinase" evidence="8">
        <location>
            <begin position="17"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00050304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00066392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036979-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="394" mass="42772" checksum="AAA7E294C7B8AB72" modified="2014-04-16" version="1">MRFTPTLLGFVAAVAAHGDHDQEPLAGPHESLWYNTLPGDGGTQADSVFSGISTFGRLKYHPCLSSNVQYDIAFIGAPFDTGTSYRPGARFGPSGIRQGSRRLNLYGGYNVPLEANPFNSWAKIIDCGDIPVTSYDNAYALQQIEQGHNLLLSRAPYTHANKPGPSKHGKTLPRMITLGGDHTITLPLLRSVHREYGPITVIHFDSHLDTWRPKVFGGSPSEQASINHGTYFFHAAQEGLLANDSNIHAGIRTTLSGPSDYENDGYCGFEIVEAREIDKIGIDGIVKKIKDRVGLEKPVYLSIDIDTLDPAFAPATGTPETGGWTTRELRTIIRGLEGINLIGADIVEVAPAYDTNAELTTMAAADTLYEVMTLMVKRGPLSYMGAPAKETIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1Z8</accession>
    <name>W6Z1Z8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_5020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687652.1">
        <property type="nucleotide sequence ID" value="XM_007689462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1Z8"/>
    <dbReference type="GeneID" id="19124467"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5020"/>
    <dbReference type="eggNOG" id="ENOG502SH94">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_3_2_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF8">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="532" mass="57194" checksum="0C5E69E8F1B58C10" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2D8</accession>
    <name>W6Z2D8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_25991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687562.1">
        <property type="nucleotide sequence ID" value="XM_007689372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2D8"/>
    <dbReference type="STRING" id="930090.W6Z2D8"/>
    <dbReference type="GeneID" id="19120861"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25991"/>
    <dbReference type="eggNOG" id="ENOG502SPD8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_386336_0_0_1"/>
    <dbReference type="OrthoDB" id="25896at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="810" mass="89370" checksum="60DC9A9568923D84" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2I8</accession>
    <name>W6Z2I8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687518.1">
        <property type="nucleotide sequence ID" value="XM_007689328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2I8"/>
    <dbReference type="GeneID" id="19123007"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36377"/>
    <dbReference type="eggNOG" id="ENOG502T0CM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_806512_0_0_1"/>
    <dbReference type="OrthoDB" id="3939315at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="344" mass="38998" checksum="A35E2554C5F8B53E" modified="2014-04-16" version="1">MFRLPNYSAPRGESIALSPCPVTPKSNVYAEEKDPFDALRRASATSSEETYSEEPLSPTSTWSNSTRPNSSPPYTPETSVPRVIAPARRPIIKSKTFPAPERIPRSTGTPSERLESILPDLLPLDDQSKTLRLQAPFIYETQSRNLPKYQLQQTLDRSSGPSMHLNIRRIQPHETRPCSVPAIFAAQDRRIRYDEEGTLYTISDFDMKGRAENALRGSIQLTSGKTLWGGQWTRIWHVTRCRARHSRCDYRGSCEPEKHLLFCIKKGVWEDAEGVVVGREESRRVGSWGGDGLATRWKGVGSERESRALEMTDAVRRDQTKSDLLVACWVMRLWMAGEFVWDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z382</accession>
    <name>W6Z382_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_104327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964072">
        <property type="protein sequence ID" value="EUC42119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691359.1">
        <property type="nucleotide sequence ID" value="XM_007693169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z382"/>
    <dbReference type="GeneID" id="19118490"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104327"/>
    <dbReference type="eggNOG" id="ENOG502RIRZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164229_0_0_1"/>
    <dbReference type="OrthoDB" id="3677768at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889495" description="AA1-like domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="12469" checksum="EB9F57A957804C20" modified="2014-04-16" version="1">MFTKTLIGFVAALSAAVALPTTTAGPKQVRMHVFGEDNCNGPATLMSVDADKCYEFAPGIKSLRVVHHDDSIRYNSLNVYSAPNCESGPVLQPILNDGCSAVVAYKAIKLSIDTPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3F7</accession>
    <name>W6Z3F7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688972.1">
        <property type="nucleotide sequence ID" value="XM_007690782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3F7"/>
    <dbReference type="GeneID" id="19124878"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6205"/>
    <dbReference type="eggNOG" id="ENOG502RM27">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162804_1_0_1"/>
    <dbReference type="OrthoDB" id="2279190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="92" mass="9551" checksum="9264AC9DEB463D62" modified="2014-04-16" version="1">MSTMESTIRPTGYGSDSESEGQASGGRKVSANVGPVPSSATLNRPAGNIIKGPVDDNGKQKDAALLIGIKLDLEAEIHLTARIRGDITIGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z482</accession>
    <name>W6Z482_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_47520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688743.1">
        <property type="nucleotide sequence ID" value="XM_007690553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z482"/>
    <dbReference type="GeneID" id="19124362"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_47520"/>
    <dbReference type="HOGENOM" id="CLU_1998079_0_0_1"/>
    <dbReference type="OrthoDB" id="3862662at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="102" mass="11802" checksum="D97C08EF93A290F9" modified="2014-04-16" version="1" fragment="single">VLELLSAIYESRVPIEPHHLPERDRRLLAEYGQKQAKTHKIEEWKNLPLTTEEQRRTWWLKKSERIAKAAETSGDRITQKSPTATSPWAAGSSRTIHDESTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z485</accession>
    <name>W6Z485_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like-conjugating enzyme ATG10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autophagy-related protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_97974</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688958.1">
        <property type="nucleotide sequence ID" value="XM_007690768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z485"/>
    <dbReference type="STRING" id="930090.W6Z485"/>
    <dbReference type="GeneID" id="19129159"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97974"/>
    <dbReference type="eggNOG" id="KOG4741">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072332_0_0_1"/>
    <dbReference type="OrthoDB" id="4089664at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061651">
        <property type="term" value="F:Atg12 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="214" mass="23704" checksum="4678D789533CB551" modified="2014-04-16" version="1">MPVAFPCLGEAEFEQGCVRLLERFQCVRSMQTEWLSAEKMHRHGTVMLRITKPLTRASPSSNASVQDADEMLDELGDLVQDDEEALNETAVPPAIVVYDAVLSPVYQVPVLYFGIHDPLHRYPPTMTTLYDHLVVPHFRPQTQDTNTGVIGGVSMAEHPITNTPVFFIHPCQTAQVMQASLHEDTTAEAYLMAWIGALGKPVGLNIPLVLAQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4B2</accession>
    <name>W6Z4B2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_97763</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688894.1">
        <property type="nucleotide sequence ID" value="XM_007690704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4B2"/>
    <dbReference type="STRING" id="930090.W6Z4B2"/>
    <dbReference type="GeneID" id="19129122"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97763"/>
    <dbReference type="eggNOG" id="KOG1649">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014421_2_0_1"/>
    <dbReference type="OrthoDB" id="10258327at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="250"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="438"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="262"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="65609" checksum="ED994AB0E2C58183" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4B5</accession>
    <name>W6Z4B5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rpr2-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_92417</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the eukaryotic/archaeal RNase P protein component 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686927.1">
        <property type="nucleotide sequence ID" value="XM_007688737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4B5"/>
    <dbReference type="STRING" id="930090.W6Z4B5"/>
    <dbReference type="GeneID" id="19128073"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92417"/>
    <dbReference type="eggNOG" id="KOG4394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079140_1_1_1"/>
    <dbReference type="OrthoDB" id="128536at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17710" checksum="0CA76E4FEDCA5E14" modified="2014-04-16" version="1">MSKVKAPKAKGIPNKHLHARSSFLYQAATYLTLQTAEAADTPQDKQAAPKSPNRLSLALSLSSDLQQVSRKGQLRLAVSLKRTLCKSCNSVLIPGRTATHRIENESKCGKKPWADVLVVTCGVCAGQKRFPAGAAPRVKKGKREMVSAVETPMTGEDTPVLTGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4L3</accession>
    <name>W6Z4L3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex non-core subunit NAF1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Nuclear assembly factor 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_39393</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
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    <comment type="similarity">
        <text evidence="2">Belongs to the NAF1 family.</text>
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        <property type="protein sequence ID" value="EUC42549.1"/>
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        <property type="nucleotide sequence ID" value="XM_007692733.1"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
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        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
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        <property type="entry name" value="Naf1"/>
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        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633">
        <property type="entry name" value="H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633:SF1">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="21"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
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            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
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        <location>
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        </location>
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
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    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="408"/>
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        <location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
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        </location>
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        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="10">
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            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
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            <end position="712"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="10">
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
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        <location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00021438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00076743"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="856" mass="90876" checksum="D260D1668A9DBF65" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4U9</accession>
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        <recommendedName>
            <fullName evidence="5">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="6" type="ORF">COCMIDRAFT_5759</name>
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    <organism evidence="6 7">
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
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    <dbReference type="PANTHER" id="PTHR45763:SF46">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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            <end position="287"/>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC45005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5R4</accession>
    <name>W6Z5R4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_102275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964045">
        <property type="protein sequence ID" value="EUC42899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692374.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19118047"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102275"/>
    <dbReference type="eggNOG" id="KOG4561">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034597_0_1_1"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="78"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="326" mass="36634" checksum="C2BBA0C82BFDD529" modified="2014-04-16" version="1">MSLVDTVLRPNMRDPLPPPSLLVQASKPFADKLSLTTLPYHVHEILLGFLGYHFILYVLSPAVSRLVCPKAYHGFNKRTRLNWDIHWVSMIQSLFICGAALWVIFKDEERHAMDWRGRLWGYTPASGMVQGFAAGYFLWDLQISTQYISIAGVSALIHAIGALAVTCIGFKPFGNYYGLSFVLYELSTPFLNIHWFCDKLGMTGSKLQLYNGIALLVTFFGCRIVWGTYQSIMIYSDIYKALTISQTDGMSSLLEAQKCDGSTNSSMGLDGSGNCYGDLPMWLVCVYLVGNTALSMLNFFWFNQMIKAVRKRFVPADEKAQAKKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5V5</accession>
    <name>W6Z5V5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bacterial surface antigen (D15) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_90941</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAM50/omp85 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686350.1">
        <property type="nucleotide sequence ID" value="XM_007688160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5V5"/>
    <dbReference type="STRING" id="930090.W6Z5V5"/>
    <dbReference type="GeneID" id="19127790"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90941"/>
    <dbReference type="eggNOG" id="KOG2602">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014798_3_1_1"/>
    <dbReference type="OrthoDB" id="1724197at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.50:FF:000008">
        <property type="entry name" value="Mitochondrial outer membrane beta-barrel protein Tob55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF18">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="7">
        <location>
            <begin position="170"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="511" mass="55733" checksum="FA26304221AE7881" modified="2014-04-16" version="1">MASPHEDDVFERLKNGTDLKEQQRQQDEINARLQAQQQRAQQRLGELVEDNTSLPVTISSVRVLHANRTRRSFLERVVEPLLSANRTEPYTLEEALKEVGEATDKLNRFGIFKSPISVYLDRPSQTIATSSPTDVDVYISAIERGNYTIKTGTEAGASEADAYVHAELRNLFGGAETLNAHGSLGTRTRSAYSLAFDTPILANPDLKFQLNGFASSTLKSWASHEEVLKGGNSKLLWRMKNGATHEIGYSAIWRQITSLAENASPSIRADAGDSFKSSITHTWLQDKRDYPLLPNRGYMMKSVSELAGFGPLKGDTAFWKSEVESQVALPFGNTGITLTAGLRGGLLYPMKLAGENQYQASRINDRFQLGGPNNVRGFRLAGLGPRDGPDSLGGDIYAAGGASLLLPIPRVGKETPLRLQAFINGGRLLALKNPNSKKEDGSFGSSSDVYGAIRKSFSTLTAEMPSAAAGFGLVYAHPVARFEINFSLPLVMRAKEESRKGLSFGVGIEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z712</accession>
    <name>W6Z712_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_95122</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963981">
        <property type="protein sequence ID" value="EUC45583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687892.1">
        <property type="nucleotide sequence ID" value="XM_007689702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z712"/>
    <dbReference type="STRING" id="930090.W6Z712"/>
    <dbReference type="GeneID" id="19128589"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95122"/>
    <dbReference type="eggNOG" id="ENOG502QPVP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011455_2_1_1"/>
    <dbReference type="OrthoDB" id="3163292at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF21">
        <property type="entry name" value="REGULATORY PROTEIN LEU3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="71"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="585"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC45583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="705" mass="79607" checksum="7C88332F413E2567" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z783</accession>
    <name>W6Z783_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_28082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964029">
        <property type="protein sequence ID" value="EUC43424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690041.1">
        <property type="nucleotide sequence ID" value="XM_007691851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z783"/>
    <dbReference type="GeneID" id="19121238"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28082"/>
    <dbReference type="HOGENOM" id="CLU_1635081_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="162" mass="17868" checksum="B7477FB3A94F3DDD" modified="2014-04-16" version="1">MSLASGGKLVGQHFHVVLSVYGTTPSRRGLVERPENAPSLLKDRKCRAHGGEAHTAKVLFSSAYYRSKSASAAETAITSAQTTPSRRVLLVTSEPLLGAQESRWPMETTRPRVEPPGAAVPFALNHMRVIDFRATQRPTVIRSWQSRKLRKRYQCPGILSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z839</accession>
    <name>W6Z839_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7779 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964235">
        <property type="protein sequence ID" value="EUC39861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693619.1">
        <property type="nucleotide sequence ID" value="XM_007695429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z839"/>
    <dbReference type="STRING" id="930090.W6Z839"/>
    <dbReference type="GeneID" id="19119585"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110356"/>
    <dbReference type="eggNOG" id="ENOG502RMUE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_7_1"/>
    <dbReference type="OrthoDB" id="6161812at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056681">
        <property type="entry name" value="DUF7779"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205">
        <property type="entry name" value="NB-ARC AND TPR DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205:SF1">
        <property type="entry name" value="ZU5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25000">
        <property type="entry name" value="DUF7779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7779" evidence="1">
        <location>
            <begin position="487"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="964" mass="108206" checksum="F4A6D8AE172993BB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8A2</accession>
    <name>W6Z8A2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Adenylyltransferase and sulfurtransferase uba4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Common component for nitrate reductase and xanthine dehydrogenase protein F</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ubiquitin-like protein activator 4</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Molybdopterin-synthase adenylyltransferase</fullName>
                <ecNumber evidence="14">2.7.7.80</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="14">Adenylyltransferase uba4</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="14">Sulfur carrier protein MOCS2A adenylyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">Molybdopterin-synthase sulfurtransferase</fullName>
                <ecNumber evidence="14">2.8.1.11</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="14">Sulfurtransferase uba4</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="14">Sulfur carrier protein MOCS2A sulfurtransferase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="primary">uba4</name>
        <name evidence="14" type="synonym">cnxF</name>
        <name evidence="17" type="ORF">COCMIDRAFT_36322</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as a nucleophile towards urm1 and mocs2a. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H(+) = [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:43616"/>
            <dbReference type="Rhea" id="RHEA-COMP:12159"/>
            <dbReference type="Rhea" id="RHEA-COMP:12202"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:90618"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="EC" id="2.7.7.80"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly-AMP + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] + AH2 = [molybdopterin-synthase sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + L-cysteinyl-[cysteine desulfurase] + A + AMP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48612"/>
            <dbReference type="Rhea" id="RHEA-COMP:12157"/>
            <dbReference type="Rhea" id="RHEA-COMP:12158"/>
            <dbReference type="Rhea" id="RHEA-COMP:12159"/>
            <dbReference type="Rhea" id="RHEA-COMP:19907"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:90618"/>
            <dbReference type="ChEBI" id="CHEBI:232372"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="14">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="14">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="14">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.80" evidence="14"/>
    <dbReference type="EC" id="2.8.1.11" evidence="14"/>
    <dbReference type="EMBL" id="KI963973">
        <property type="protein sequence ID" value="EUC46018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687474.1">
        <property type="nucleotide sequence ID" value="XM_007689284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8A2"/>
    <dbReference type="STRING" id="930090.W6Z8A2"/>
    <dbReference type="GeneID" id="19122997"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36322"/>
    <dbReference type="eggNOG" id="KOG2017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013325_1_2_1"/>
    <dbReference type="OrthoDB" id="10261062at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061605">
        <property type="term" value="F:molybdopterin-synthase adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061604">
        <property type="term" value="F:molybdopterin-synthase sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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</entry>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36851">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="60788" checksum="C0E0BA8AC7A49EB3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9L8</accession>
    <name>W6Z9L8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="10">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_108943</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="10"/>
    <dbReference type="EMBL" id="KI964169">
        <property type="protein sequence ID" value="EUC40396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693094.1">
        <property type="nucleotide sequence ID" value="XM_007694904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9L8"/>
    <dbReference type="STRING" id="930090.W6Z9L8"/>
    <dbReference type="GeneID" id="19119335"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108943"/>
    <dbReference type="eggNOG" id="ENOG502SING">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_4_0_1"/>
    <dbReference type="OrthoDB" id="3496539at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF2">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="9 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889832" description="AA9 family lytic polysaccharide monooxygenase" evidence="12">
        <location>
            <begin position="18"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="13">
        <location>
            <begin position="285"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC40396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="320" mass="33496" checksum="4B77D5E0515D087D" modified="2014-04-16" version="1">MKFSAALIAAVAQVASAHYFFDKAIVAGAETSAFKYVRQSTRATKYNPIKFSSNPAADIRDNSHVDGPDIVCNQGAFSSAARTDVLTVKAGDEIRLKLAVGAKFQHPGPEFVYLAKAPGSVKSFDGKDGAWFKIHELGVCDGGDFTSTAWCDYNRDWVAAKIPNDTPNGEYLARFEHIGVHRSHVNQPEHYVSCMQIKVEGGGNGTPGPTVKFPGAYKATDPYANFSIYNGRKAFPMPGPAVWKGGAGTASTGSSAPANNAPAAPAPTTLAVQPAPAATPAPGAACAAQWAQCGGSGFTGAKCCANGSCKTMNPYYSQCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9Z5</accession>
    <name>W6Z9Z5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_6326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964006">
        <property type="protein sequence ID" value="EUC44349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689119.1">
        <property type="nucleotide sequence ID" value="XM_007690929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9Z5"/>
    <dbReference type="GeneID" id="19124923"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6326"/>
    <dbReference type="eggNOG" id="ENOG502SPG6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036632_5_3_1"/>
    <dbReference type="OrthoDB" id="3918601at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38794">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38794:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="2">
        <location>
            <begin position="45"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="429" mass="46985" checksum="173A11DD3D38D344" modified="2014-04-16" version="1">MAVLPFISSRHPIPRRPGSGADVGPFVNVVTWTLLITSALAVLTRLITKRALRRRIDIDDAFVMLALASSIASGGAVSLQTHNGLGRDILLLTQSQLAAYRKAEYANNLLYISTLGFAKLSIISLLMILTASKTHRNLGLSLAGFIALWTIFSMCLAAFQCGATEPWRFLGNEEMCFNVVSFWRSVGAVNILTDLALIAFPVHVVMTLQMSMSKKITILTFFGARSLDIVATAVQMIYLDGFTSPNPTKALWKWTLLAQIIECITIITSCVPYIRPLLESVPSGLYASDDLRRRGTSSEHGISRSKNSSYQLSSIVSRVGTGITRSSRKSLHTENTRIKRFLPILSQEKTTHTNSASGIPGGPRRLDGATDVEISAVHHRHTDDKRWETASTGSHSKILKTTVVSAEWEEAEFKGHDASSDEIEVIRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA70</accession>
    <name>W6ZA70_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Vacuolar membrane PQ loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_91742</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)</text>
            <dbReference type="Rhea" id="RHEA:71063"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the laat-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686672.1">
        <property type="nucleotide sequence ID" value="XM_007688482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA70"/>
    <dbReference type="GeneID" id="19127940"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91742"/>
    <dbReference type="eggNOG" id="KOG2913">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019699_0_0_1"/>
    <dbReference type="OrthoDB" id="8048523at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034486">
        <property type="term" value="P:vacuolar transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000009">
        <property type="entry name" value="PQ loop repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000012">
        <property type="entry name" value="Vacuolar membrane PQ loop repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC46865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="33291" checksum="E16A54614262D5F6" modified="2014-04-16" version="1">MLAAALSHSLSLTPHEALSGVFGSISLASWIFLLVPQLLENYKSGSADGISLAFLIVWFIGDVTNLAGALWAGLVPTVIALAVYFCFADLVLISQCLYYNMKNSRRERKSSTRSTDSVQAPLLGRRDSSNIGLPGSHRRDSAASRRRRASSLPTIPDVTTASSSEWLKNALSIFGVCAVGAAGWAIAWQIGVWVPQPTHDDAGNASDSPLGAQILGYASAICYLGARIPQIIKNQREKSCEGLSLLFFMLSLLGNATYGAGIIFHSQEKQYILTNLPWLIGSLGTMVEDVTIFIQFRVFGTGESTSALDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA80</accession>
    <name>W6ZA80_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trehalase</fullName>
            <ecNumber evidence="6">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_108313</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="6"/>
    <dbReference type="EMBL" id="KI964150">
        <property type="protein sequence ID" value="EUC40631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692858.1">
        <property type="nucleotide sequence ID" value="XM_007694668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA80"/>
    <dbReference type="STRING" id="930090.W6ZA80"/>
    <dbReference type="GeneID" id="19119220"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108313"/>
    <dbReference type="eggNOG" id="KOG0602">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006451_1_1_1"/>
    <dbReference type="OrthoDB" id="3542292at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030437">
        <property type="term" value="P:ascospore formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000026">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neutral trehalase Ca2+ binding" evidence="8">
        <location>
            <begin position="82"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="729" mass="83941" checksum="81EC91AB9B4B8279" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAE0</accession>
    <name>W6ZAE0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_25236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686691.1">
        <property type="nucleotide sequence ID" value="XM_007688501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAE0"/>
    <dbReference type="GeneID" id="19120726"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25236"/>
    <dbReference type="HOGENOM" id="CLU_1805833_0_0_1"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="143" mass="16106" checksum="A10AEA85253CDD10" modified="2014-04-16" version="1">MVVVTSKPIQPLASALPSLSNKHHFRQASRFTLPMTLQSIADLQKKDVNHPNYTTWTEPQNFFTWTYRTAQYTDQGLSRMHRLDSTIRKVQRPTPNANPLIGLTLSLFLSARKIVARNSVTAPDVMHFPVRHAAGVSLNADRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC12</accession>
    <name>W6ZC12_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_5738</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the 2nd section; belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the shikimate kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC44979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688460.1">
        <property type="nucleotide sequence ID" value="XM_007690270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC12"/>
    <dbReference type="STRING" id="930090.W6ZC12"/>
    <dbReference type="GeneID" id="19124721"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5738"/>
    <dbReference type="eggNOG" id="KOG0692">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008871_0_1_1"/>
    <dbReference type="OrthoDB" id="4415835at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000386">
        <property type="entry name" value="Quinate repressor protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090">
        <property type="entry name" value="AROM/DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090:SF27">
        <property type="entry name" value="QUINATE REPRESSOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="5">
        <location>
            <begin position="547"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase" evidence="4">
        <location>
            <begin position="689"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="SDH C-terminal" evidence="6">
        <location>
            <begin position="839"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="891" mass="98415" checksum="A22099B8D7F484B0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCZ0</accession>
    <name>W6ZCZ0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_88820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685594.1">
        <property type="nucleotide sequence ID" value="XM_007687404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCZ0"/>
    <dbReference type="STRING" id="930090.W6ZCZ0"/>
    <dbReference type="GeneID" id="19127351"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88820"/>
    <dbReference type="HOGENOM" id="CLU_127753_1_0_1"/>
    <dbReference type="OrthoDB" id="285219at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14361">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052617">
        <property type="entry name" value="Huntingtin-int_K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038922">
        <property type="entry name" value="HYPK_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184:SF2">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nascent polypeptide-associated complex subunit alpha-like UBA" evidence="2">
        <location>
            <begin position="59"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="103" mass="10679" checksum="CCDFC31D5E598AAD" modified="2014-04-16" version="1">MAEPQPPTIHEGASTPALNDAASTPTNGAKKEVDGKALDKAMKGLSVKDKAEDEKKKNVKIDAGDVVVLVSELEITKAKATELLRANEGDAVKALVAFVTAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCZ9</accession>
    <name>W6ZCZ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_5515</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
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        <property type="protein sequence ID" value="EUC45314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007689987.1"/>
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    <dbReference type="STRING" id="930090.W6ZCZ9"/>
    <dbReference type="GeneID" id="19124641"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5515"/>
    <dbReference type="eggNOG" id="KOG1304">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="1684102at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
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        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0061459">
        <property type="term" value="F:L-arginine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0005290">
        <property type="term" value="F:L-histidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015189">
        <property type="term" value="F:L-lysine transmembrane transporter activity"/>
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        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:1990818">
        <property type="term" value="P:L-arginine transmembrane export from vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0089708">
        <property type="term" value="P:L-histidine transmembrane export from vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0089707">
        <property type="term" value="P:L-lysine transmembrane export from vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000067">
        <property type="entry name" value="Transmembrane domain transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="535"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="568"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="615"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="657"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="680"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="714"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="351"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="752" mass="82000" checksum="87A293DF3D1501A6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD78</accession>
    <name>W6ZD78_COCMI</name>
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        <recommendedName>
            <fullName evidence="2 3">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_105593</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
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        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF116">
        <property type="entry name" value="TYROSINASE"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="TYROSINASE_2"/>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
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            <end position="326"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="394" mass="42892" checksum="12D49DDBF984F3A7" modified="2014-04-16" version="1">MKISTYLSVALAGSTSAKFMENDRLAAEGIAKLRTHLAENGIPNPGTCTLDKASVRREWATLSRKERIAFNDAVNCLHKLPAKTSASVAPGAKSRYDDLVVTHIQQSLNIHGTGNFLTWHRYFTWVFEQMIRKECGYKGTFPYYNWAHYASDPKSGPFFDGSASSMSGDGSYVPGRNSSCFPWDGIAGPCYMHLAPGSGGGCVTSGPFKDFKINMGPLQTMLQLPGGGLPKNPQANRLGYNPRCLRRDISQQAANATTDAEVVRLLKNYTDIATFQREYQGAFADGRMGVHTGGRKLHYTMGGDAGSDFYNSPADPAFYPHHGMIDRVWWTWQNLDLKNRERALAGSAGGIGDTTAKNATLGDALTVGEYVGYPNITIGDAMSTVGGPFCYIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDB2</accession>
    <name>W6ZDB2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_89076</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PET117 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDB2"/>
    <dbReference type="STRING" id="930090.W6ZDB2"/>
    <dbReference type="GeneID" id="19127402"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89076"/>
    <dbReference type="eggNOG" id="ENOG502S7B1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161486_3_1_1"/>
    <dbReference type="OrthoDB" id="76305at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031568">
        <property type="entry name" value="Pet117"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28163">
        <property type="entry name" value="PROTEIN PET117 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28163:SF1">
        <property type="entry name" value="PROTEIN PET117 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15786">
        <property type="entry name" value="PET117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9895" checksum="A810D2D25720B5C6" modified="2014-04-16" version="1">MSRASQITLATTCVTAVGIVAFVHWSQKADKAAMHMGVVRDFEQQRIKRERQADFEMQRELEQEYRKYQTVSDGGGPEPRPDQGPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDQ4</accession>
    <name>W6ZDQ4_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_2987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDQ4"/>
    <dbReference type="GeneID" id="19121582"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2987"/>
    <dbReference type="eggNOG" id="ENOG502SDCC">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012103_1_0_1"/>
    <dbReference type="OrthoDB" id="2555519at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38701">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38701:SF1">
        <property type="entry name" value="UP-REGULATED DURING SEPTATION PROTEIN 1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="308"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="407"/>
            <end position="424"/>
        </location>
    </feature>
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        <location>
            <begin position="507"/>
            <end position="531"/>
        </location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        <location>
            <begin position="679"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="746" mass="80099" checksum="07F43101D6EE7531" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEL7</accession>
    <name>W6ZEL7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_87441</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAUS1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC48460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685083.1">
        <property type="nucleotide sequence ID" value="XM_007686893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEL7"/>
    <dbReference type="GeneID" id="19127059"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87441"/>
    <dbReference type="eggNOG" id="ENOG502S1U0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068908_0_0_1"/>
    <dbReference type="OrthoDB" id="5372507at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070652">
        <property type="term" value="C:HAUS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026243">
        <property type="entry name" value="HAUS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570:SF1">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25762">
        <property type="entry name" value="HAUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="188"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="298" mass="33746" checksum="D6C3E4D5CC64804B" modified="2014-04-16" version="1">MDSLTPSDLFSPSKARQQRAQAQDWAQIDSWLSYKYAGRTVPTFERNDETLKVLRELSVANERADEERAVFERVEREALRELDEVQRNDDDERILSRLRASLTPEGEQALDALGSTAVTLNTPTANPESIAHALIYNTTTSQNLTNQLAHIATLQGYVDKQQSLLRTQLHELQTNPAFTTPANLQRQTTEQTRQVKHLRTKIREYEDKLSSLQSSQSRSMTPGSKNIASAEAINDMLEQQKALDGLREKVEGIEREVAEFAGLPADKEAARKEVGKLEVKLDEVRKRRDELFEGLVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFQ9</accession>
    <name>W6ZFQ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_29042</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964065">
        <property type="protein sequence ID" value="EUC42336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691152.1">
        <property type="nucleotide sequence ID" value="XM_007692962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFQ9"/>
    <dbReference type="STRING" id="930090.W6ZFQ9"/>
    <dbReference type="GeneID" id="19121427"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29042"/>
    <dbReference type="eggNOG" id="ENOG502SPFX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_12_8_1"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF158">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="64"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="368" mass="40313" checksum="0E9158849C09EA31" modified="2014-04-16" version="1">MAMTTPAAALPTGPGGMPGYIWNLPAMPPPKGQTSNFVNPESRDMELIVMNAVFLSATVLAVAVRFIARRTAKDVVGWDGLMCILATMASAAHSGLMISGLNIGYGRHLWDIRAVTLTHSRLLQLNQLSTLYIVGICFAKLSVLLLYLRFFNVVEFTRHLIYFGIFLTLLSSAAFMGHEIAQAVLCMGVSAVSNQFCKAVNKVVTIQAAVNVFIDFYILVIPLQQVWKLNMDFQRKLGVCAVFGVGLVACIVSVVRMGWSIRNLNESDHFWAAVLTSEMTIVELNTVIIAPCLVFAPAFVKRSRSGLSSLRTRLVSSGQRTPSKDSLSDVYHDKTYSDAPKPQIVPLQFVMTPKDYIEPAKPAAAHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFT3</accession>
    <name>W6ZFT3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vps41 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_25586</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688900.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZFT3"/>
    <dbReference type="GeneID" id="19120787"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25586"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="244107at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:HOPS complex"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Vacuolar assembly protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Beta-prop_Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23411">
        <property type="entry name" value="Beta-prop_Vps41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23556">
        <property type="entry name" value="TPR_Vps41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps41 beta-propeller" evidence="6">
        <location>
            <begin position="172"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Vps41 beta-propeller" evidence="6">
        <location>
            <begin position="384"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="3">
        <location>
            <begin position="909"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="561"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1205"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="881"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1210"/>
            <end position="1219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1325" mass="144943" checksum="4D069FF76FEAA9A1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG03</accession>
    <name>W6ZG03_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_31946</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.91"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682689.1">
        <property type="nucleotide sequence ID" value="XM_007684499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG03"/>
    <dbReference type="STRING" id="930090.W6ZG03"/>
    <dbReference type="GeneID" id="19121998"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31946"/>
    <dbReference type="eggNOG" id="ENOG502QPHV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020817_3_2_1"/>
    <dbReference type="OrthoDB" id="412382at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016162">
        <property type="term" value="F:cellulose 1,4-beta-cellobiosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.100.10:FF:000001">
        <property type="entry name" value="Glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889994" description="Glucanase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC50742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="456" mass="48442" checksum="43BFD401E33E302E" modified="2014-04-16" version="1">MYRTLAFASLSLYGAARAQQVGTSTTETHPKLTWQTCTGTGGTNCSNKSGSIVLDSNWRWAHNVGGYTNCYTGNTWSTQYCADGDSCTKNCAIDGADYSGTYGITTSNNALSLKFVTKGSYSSNIGSRTYLMESDTKYQMFNLINKEFTFDVDVSKLPCGLNGALYFVEMAADGGIGKGNNKAGAKYGTGYCDSQCPHDIKFINGKANVEGWNPSDADPNGGAGKIGACCPEMDIWEANSISTAYTPHPCKGTGLQECSDAVSCGDGDNRYSGQCDKDGCDFNSYRMGVKDFYGPGATLDTTKKMTVITQFLGSGSSLSEIKRFYVQNGKVFKNSQSAIAGVTGNSITESFCTAQKKVFGDTSSFANLGGLNEMGASLARGHVLVMSLWDDHAVNMLWLDSTYPTDADPSKLGAARGSCPTTSGKPEDVEKNSPDATVVFSNIKFGPIGSTFAQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGA7</accession>
    <name>W6ZGA7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_23301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684502.1">
        <property type="nucleotide sequence ID" value="XM_007686312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGA7"/>
    <dbReference type="STRING" id="930090.W6ZGA7"/>
    <dbReference type="GeneID" id="19120412"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23301"/>
    <dbReference type="eggNOG" id="ENOG502SIPI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021538_0_0_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="630" mass="70917" checksum="D9A2BF101CC5C0D2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGG4</accession>
    <name>W6ZGG4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF3176 domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_85359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684324.1">
        <property type="nucleotide sequence ID" value="XM_007686134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGG4"/>
    <dbReference type="GeneID" id="19126652"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85359"/>
    <dbReference type="eggNOG" id="ENOG502R1NH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015092_0_1_1"/>
    <dbReference type="OrthoDB" id="5242705at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="579"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="678" mass="76334" checksum="5800B946F84A8B3B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH30</accession>
    <name>W6ZH30_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein N-terminal and lysine N-methyltransferase EFM7</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM7</name>
        <name evidence="6" type="ORF">COCMIDRAFT_80344</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682460.1">
        <property type="nucleotide sequence ID" value="XM_007684270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZH30"/>
    <dbReference type="STRING" id="930090.W6ZH30"/>
    <dbReference type="GeneID" id="19125653"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80344"/>
    <dbReference type="eggNOG" id="KOG2920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032409_0_0_1"/>
    <dbReference type="OrthoDB" id="46564at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071885">
        <property type="term" value="F:N-terminal protein N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000183">
        <property type="term" value="P:rDNA heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03223">
        <property type="entry name" value="Methyltr_EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025784">
        <property type="entry name" value="EFM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF10">
        <property type="entry name" value="PROTEIN N-TERMINAL AND LYSINE N-METHYLTRANSFERASE EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51560">
        <property type="entry name" value="SAM_MT_NNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC51162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="252" mass="28518" checksum="ED5C04D85A604084" modified="2014-04-16" version="1">MSSDAEDEGLDLFQEPADYYQPEKQATFASHKLLSGKDLTVRLVGHNPLWGHFLWNAGRTISTYLEENANELVKDKIVLELGAGAGLPSLVCALKGAGQTVVTDYPDADLIENLRYNIDHCELLSKPPRIVAEGYLWGAPTKDLIKHLDNDSGFDVLILADLLFNHSEHEKLIKTVELTLKKAPTSRAFVFFSPYRPWLYEKDIAFFDLARNAGFTVEKMFEKVMDKVMFEEDPGDELLRRTVFAYELTWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHD8</accession>
    <name>W6ZHD8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_84846</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684138.1">
        <property type="nucleotide sequence ID" value="XM_007685948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHD8"/>
    <dbReference type="STRING" id="930090.W6ZHD8"/>
    <dbReference type="GeneID" id="19126552"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84846"/>
    <dbReference type="eggNOG" id="ENOG502S997">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033337_0_0_1"/>
    <dbReference type="OrthoDB" id="2152896at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="370"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC49415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="430" mass="46006" checksum="5233A343447CEB0C" modified="2014-04-16" version="1">MAGSLPKNRTHSQSISAANLHPAHRVTRRKSMSQTPVTNIAAIAAAAKGMSGAPLEGASSSGSSSGPRRSSKPASQFRGPSMAMASTMASSVPAHGAQFGASSYGSAAKSEALTDGPTLATMLEQDKANAKSRNRRASEGSRLSKGDGKRSGSELRCEKCGKGYKHSSCLTKHLWEHTPEWQYTSKLLISKHQQVQLLEAASVLVAMNKESDGEHSDRSSPPASGSSDVREDLSSTETTPPPQLDDHAVGSYPHSHFGTRSMKRYSTNSSAYSQSYQSTVFSDNGNGNAHGHFRQWSNVSDRPTTSGTSVAGSYHDDANDHADLAAAVGLLSCSYGTPKTGPVALPADAPPVPPLPAKYFDLNTRTLSGSTTVTAQQSSMRNSYRHPSESKDVDMDDDHFADEEDYRYSNARSRSRIDEDDDEIFGRMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHH7</accession>
    <name>W6ZHH7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_38979</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964042">
        <property type="protein sequence ID" value="EUC43006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690463.1">
        <property type="nucleotide sequence ID" value="XM_007692273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHH7"/>
    <dbReference type="STRING" id="930090.W6ZHH7"/>
    <dbReference type="GeneID" id="19123590"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38979"/>
    <dbReference type="eggNOG" id="ENOG502QRET">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020125_0_0_1"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF4">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE APTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887065" description="Tyrosinase copper-binding domain-containing protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="9">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="10">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC43006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="773" mass="85589" checksum="DCE6E52CCB31D2F9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIL6</accession>
    <name>W6ZIL6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LYR motif-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_38620</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in efficient integration of the N-module into mitochondrial respiratory chain complex I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964029">
        <property type="protein sequence ID" value="EUC43421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690049.1">
        <property type="nucleotide sequence ID" value="XM_007691859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIL6"/>
    <dbReference type="STRING" id="930090.W6ZIL6"/>
    <dbReference type="GeneID" id="19123510"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38620"/>
    <dbReference type="eggNOG" id="ENOG502SAMX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151409_0_1_1"/>
    <dbReference type="OrthoDB" id="74240at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd20262">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045293">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF0">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="7">
        <location>
            <begin position="33"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="104" mass="12061" checksum="B6D57E570CFF97CD" modified="2014-04-16" version="1">MLRRYATVASKPLSRLGARGKSPVSLDHFIQRQRVLALWRDIVRSTANIPDEAARRDMREFARSEFEQHRQVTDLGHIRYLISHGKTQFQAMRDTLINSGILTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIM9</accession>
    <name>W6ZIM9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_83504</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683681.1">
        <property type="nucleotide sequence ID" value="XM_007685491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIM9"/>
    <dbReference type="STRING" id="930090.W6ZIM9"/>
    <dbReference type="GeneID" id="19126273"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83504"/>
    <dbReference type="eggNOG" id="ENOG502R6QN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003836_1_1_1"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057215">
        <property type="entry name" value="DUF7893"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF54">
        <property type="entry name" value="DNA METHYLTRANSFERASE DIM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25423">
        <property type="entry name" value="DUF7893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BAH" evidence="10">
        <location>
            <begin position="331"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="BAH" evidence="10">
        <location>
            <begin position="470"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1017"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1029"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1046"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1072"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1114" mass="126124" checksum="FA76853AEC7D2310" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ58</accession>
    <name>W6ZJ58_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_100338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964023">
        <property type="protein sequence ID" value="EUC43641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689851.1">
        <property type="nucleotide sequence ID" value="XM_007691661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ58"/>
    <dbReference type="GeneID" id="19117658"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100338"/>
    <dbReference type="HOGENOM" id="CLU_2694395_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="74" mass="8430" checksum="B180B5EF9474A1F0" modified="2014-04-16" version="1" fragment="single">GQRRILVSRILKLGAEGKDGDPEKNFPHKTFFFVVVAVVIPTFFYHLEPGLGTSLPHNTSSLTRVPGRYMYRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ71</accession>
    <name>W6ZJ71_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GET1</name>
        <name evidence="13" type="ORF">COCMIDRAFT_1255</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Schackwitz W."/>
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                <person name="MohdZainudin N."/>
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                <person name="Han J."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="entry name" value="Znf_C2H2_type"/>
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        <location>
            <begin position="355"/>
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    </feature>
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        <location>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <begin position="10"/>
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        </location>
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            <begin position="52"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="EMBL" id="EUC47579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="446" mass="49595" checksum="51D04E2E79C5E7BF" modified="2014-04-16" version="1">MYRQRLSGVSNSPPSMRSPPRNRTFHPYTDPVAGYQNQASGPNLERGYGWTPSPQQQLGQRVPDTQSQRADHLLATRRLTYAEVLQKQTPFANQYNSARPSGLGSILAENMQPWAPPRRGPGTVDVPSDQDPSSYERIFAMYTNGGNSEGAREPSPYHNSIASGSSVLPTPSGPVHGNLGNDDEPWSTVHQRGYENRMGLIRPHLPSMPQMDPSAFQDNHASEGTYLTSPDLYNLSHVQCFNKDIQSTIQPVQPTRTNSGYGQADYGVTKNTNHLRAPRQVPNQRASGGVNTHRVNTNPVARSGDGRSYGSPSTTSMHRDSLHCPHCDTKFTGNKYGKGNLARHIRHKHQDHPKISCGYCGELFQRTDARLKHHRKKHPELEPPTPNSQRSGQSSTQTRTGPTHDVHSNESRSFNGFEAFQDYFYYPGNMGQPEPHPDDLRGLTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJR6</accession>
    <name>W6ZJR6_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">COCMIDRAFT_89390</name>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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            <begin position="1"/>
            <end position="38"/>
        </location>
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            <begin position="407"/>
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            <begin position="7"/>
            <end position="31"/>
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    </feature>
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            <begin position="154"/>
            <end position="163"/>
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            <begin position="554"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="EMBL" id="EUC47689.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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    </evidence>
    <sequence length="630" mass="69062" checksum="2739CD3B927E16C7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKV3</accession>
    <name>W6ZKV3_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
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        </recommendedName>
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            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
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            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
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            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687158.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19127216"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88178"/>
    <dbReference type="eggNOG" id="KOG0616">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_5_1"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
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        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="82"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="345"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="366"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="367"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC48144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="402" mass="46519" checksum="E0095ABC4F8CF21D" modified="2014-04-16" version="1">MATAFKNMLHPLHHHRDKKEPPHSGPLHDRTDSAMEKPREQEKQQLAQWEAQKHTLTPDEIDIDPQKKPVGHSSKVLREQDFELIKTLGTGTFARVWLVRLKDARPGDENKVFALKILRKVDVIRLKQVEHVRNERNVLAKVAGHPFITTMVASFQSLDSLYMVLDYCPGGEVFSYLRRARRFNEPTSQFYAAEIVLILEFLHEHEGVAYRDLKPENILIDAEGHLKLVDFGFAKKVDNRETYTLCGTPEYLAPEVIRNTGHGTAVDWWAFGILVYEFLVGQPPFWDQNPMKIYEQIVEGRVRFPSAMSPTARDLISGLCTVDTSKRLGNVAGGAQRVKDHEWFKDIDWQKIYNRETQGPIVPHLRGPADTRNFDEYEPESENREPYTKELSDRWEESFKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL90</accession>
    <name>W6ZL90_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_81152</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682720.1">
        <property type="nucleotide sequence ID" value="XM_007684530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL90"/>
    <dbReference type="GeneID" id="19125813"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81152"/>
    <dbReference type="eggNOG" id="ENOG502QT05">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036005_0_1_1"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000003">
        <property type="entry name" value="Alpha-ketoglutarate-dependent taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF31">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="8">
        <location>
            <begin position="88"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="361"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="395" mass="44280" checksum="6561CE6CCB4531F2" modified="2014-04-16" version="1">MAPGLVEPQFQPNTTDTPVVASKPTNAHSYVPGRTKVKQHDDTYEYEDLRPHFPDITWPAYTEIPYIEKGQLGDPNFKNLLASATDVFDYNPKIGTEVHGVDLANLTDAQKNDLARLIATRGVVFFRDQKNLTIDKQKELGKYFGELHKHATTGVPKREGLEDVHVIFTGEGSPDLRALFTPTFLWHSDVTYELQPPSYTSLKVLTGPPRGGGGDTLWSSQYAAYDMLSPHMQKYLESLTALHSADLQAQGSRDLGRTVRREPVTTEHPLIRTNPVTGWKSLFFNPGFVTKIVGVPKTESDHIIGLLNEIVATSPEIQARFQWKEGDVAFWDNRVTNHSASYGFAPHRRHAVRVAVRAERPYLDPQSRSQEDELSERYGVPKANKDGSGIVNYND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLF0</accession>
    <name>W6ZLF0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_81004</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682754.1">
        <property type="nucleotide sequence ID" value="XM_007684564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLF0"/>
    <dbReference type="GeneID" id="19125781"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81004"/>
    <dbReference type="eggNOG" id="ENOG502SMC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_4_1"/>
    <dbReference type="OrthoDB" id="3923077at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="29"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="287"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="391" mass="43970" checksum="A0AE2684348286E4" modified="2014-04-16" version="1">MESLHENRGPVLQAVCSTFVSLAFVATVLRVYTRTRIVKAFGADDWWMVAALLFHVMFATCAIGGIHYGTGRHMSTLTNEQQYKALRYWWLCYIAYCWAMITSKISIGLFLLRVTVQNLHKWIIYTAMALTMLTGLVFFFVTLLQCTPISFFWNRQIKGGYCVNVDIIIGLTFLYSAISVISDFTFAILPFFLIWSLNMSTKTKAMLIPVLGMACVASVAVVVRMAYVMDFKDPDFLWATVDIAIWSDIEQGLAITAGSLATLRPLWREISTTLSLSSALSPSTPSGVRTPQWNGDPTSSQSRKKPLIYSMTRSLFQTEKGSPSKELDEDYGMGNLAPIRLRDDLSAQNEKTDKGFSTWRIKGGGSKVSDEECRVGEITRETYIEQERGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLR2</accession>
    <name>W6ZLR2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682489.1">
        <property type="nucleotide sequence ID" value="XM_007684299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLR2"/>
    <dbReference type="GeneID" id="19124281"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_455"/>
    <dbReference type="HOGENOM" id="CLU_657184_0_0_1"/>
    <dbReference type="OrthoDB" id="3693531at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="418" mass="46713" checksum="8F824AD7304E5600" modified="2014-04-16" version="1">MADNNIEAKVREFAELKSKAEMRDFIDKTNENIISFKNRIGVTGSVSTLIANYRAHLERVASGEQSHEVPETPSSSRAKGKQRATTVSTASLRGNDGDFEDIPDKATGLLSKLMIQLNPPISRVTKECLNVLGSSLRIHPTTEDDFSYILQPLFHVIFDVVRARNMVPLSYNHAENYQRLSQEVQKMKPVDGISHIIEPLVKGIGVEHTRRGTEDDIEVQVPAALVKELDLLSDEIHASFERWSSTFPPPPAEEILYPLDFTREEKHALRRYAKGFLEENLHIAEKNAKREDIQEALSELRANWPIAKGNMQAIAQLLLDEVKSSHSRSKPRSRSRSLASPSLASETTNAFHESSVGGELGDLEDESHAREHCGTSDQLDSRKRSLIVNSDEDDGGEDAPNQSKAKCTERRGTRSRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLU1</accession>
    <name>W6ZLU1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_87131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684952.1">
        <property type="nucleotide sequence ID" value="XM_007686762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLU1"/>
    <dbReference type="STRING" id="930090.W6ZLU1"/>
    <dbReference type="GeneID" id="19126993"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87131"/>
    <dbReference type="eggNOG" id="ENOG502SHAC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019189_9_1_1"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051035">
        <property type="entry name" value="Mito_inheritance_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36091">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36091:SF2">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="472" mass="53753" checksum="62896009F52FD7B8" modified="2014-04-16" version="1">MCDGFQLVGRIPYLFTEPRPLLVASEVATMHFLRLHGIPVPRIYGYSATSDNGAGTEYMFMELVHGKNLGDIWFDLSIEARITVVTNLVELESRLFSLTFPASGSLYHTKDMGPGLKKVEVPIADSAYDGHFCIGSDTRLNMWRGKRLNIQTDRGPYSIAALEAGAKKEIAYLTKFGRPLHPFQRLHREVHGYQLQSPSEHLSNLEKYLRTVPHLIPDGNSTLVHPTMRHPDLQLNNIFVSDDFSITSVIDWQHCTILPLFLQCGIPNSIQNYGDSISESLTFPDLPPNFDELSEYAQSQETELLRRRQLHYFYVAATASLNPTHYDALTENFGTLRRKLFEHAGDPWEGDIVTLKNDLVYLTKKWDKVVASKSNTGDETSHLCPIAFSEDEVAECLRLNDAQLEADKSLRNYRDFIGIGIEGWVPVEQYDEIKQREQEFKADVLEAADAEGEGEKIREHWIFDDFDEEEYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLX7</accession>
    <name>W6ZLX7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_97771</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688892.1">
        <property type="nucleotide sequence ID" value="XM_007690702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLX7"/>
    <dbReference type="STRING" id="930090.W6ZLX7"/>
    <dbReference type="GeneID" id="19129123"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97771"/>
    <dbReference type="eggNOG" id="ENOG502SVBS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_880008_0_0_1"/>
    <dbReference type="OrthoDB" id="5412936at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="247"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="36991" checksum="94DCAC3B51B8C286" modified="2014-04-16" version="1">MATTQSQNKQSNVSSDNNINKLTPAQTEARGILNHVLTQLQSHPHYNTTYGPWIQRNGHAQLLAFCHTLVLPQTWNFLSHRWSLDALKPLSGDLRYSGRAIYLDGILGLDKRLRIYVGQSHNLRARVAQHLNFRYRRDHSSLHYFALQESVYNVLGAVIFLPGVNSGPGTDDMALLMNVLELWMCLVFRSLPMQVLEEWLPDDGSVERKRKVGREGVVGGLNVACPLDQGREDRAFVDLRDDEDPLIKAYLKEVRRKKEEEREEEQEIVRRKEAYVEKARGYKGGDGDIRIPQWVLYSVLAGVLGYVLVSSRVGQRLRWWMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLY8</accession>
    <name>W6ZLY8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_86966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684983.1">
        <property type="nucleotide sequence ID" value="XM_007686793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLY8"/>
    <dbReference type="GeneID" id="19126962"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86966"/>
    <dbReference type="eggNOG" id="ENOG502R0VM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164903_1_0_1"/>
    <dbReference type="OrthoDB" id="4829316at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="74" mass="8382" checksum="29C768AD4D861D3E" modified="2014-04-16" version="1">MPSATQARIMWRTLSRGMVEPHPFARNPITMAPHAWRAGDLGQRFVKTSAVYFPFYAVILGWPAAAAWWFNGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM27</accession>
    <name>W6ZM27_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_37545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688835.1">
        <property type="nucleotide sequence ID" value="XM_007690645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM27"/>
    <dbReference type="GeneID" id="19123269"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37545"/>
    <dbReference type="HOGENOM" id="CLU_993923_0_0_1"/>
    <dbReference type="OrthoDB" id="3683168at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="280" mass="31839" checksum="A5DCA07ABE7C965C" modified="2014-04-16" version="1">MAGALFFTESYSSIQINKHSTAAMREVGKSPFMALPTELRCQTYSYLQEIVYEPIFPGPCMCKWDICRMPTALLQLNKTIYEELEHPSMQKLLQKANNQLLPKIVLYPTRNEMDAAYLALAHALHQVNIRFYRHFAAFATWAGCKTERFGRFVRQTLERMAIRRTCEIRFRILAHPLEVSGRGDESGDLMAYYATCGSIAALLGACRVQGVRGALGGQKDDEFTYLLSAYKREIVACLLWLACSDECLRERIHLYLVYFSNSSNPLLAAHVMVSIMVSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNL6</accession>
    <name>W6ZNL6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_85357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684323.1">
        <property type="nucleotide sequence ID" value="XM_007686133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNL6"/>
    <dbReference type="GeneID" id="19126650"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85357"/>
    <dbReference type="eggNOG" id="ENOG502SMEG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033830_3_1_1"/>
    <dbReference type="OrthoDB" id="5420247at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42029">
        <property type="entry name" value="AN04G07800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42029:SF3">
        <property type="entry name" value="AN04G07800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="425" mass="48271" checksum="CA56299945B80AB1" modified="2014-04-16" version="1">MAPLSNINGEFLAMSKRRPEPATTRTSPPTRASMTLEGGFLEAWAQGYNVGSFIILMLIVLCNYRSGILLHKLILLELLLAIWHGTFIFVEDPYYGWYLSSTATLLFISYFLHNVVAWLKIRPFLPLWGSRFFIISLLCVQPFWVVEAWSNFAYFNQLATGSRVNLRTRPWEALVRDPWWIFTTWKLINAIKKTYTFSLWTLIKINRRFSVMLACMILSISFVIIDAAISAAKLSASSGINPYWRFALVFKCASDTIFLDDFKSMLDDIIAQKFTSAADTTGPGRSMSRTGGAANKRSRSMSREEAMESNMLEGLRTPSVSTTQNSQSRSSRPGFGSYFSSKSKRMERETSSNRMEREMSSSQKARETPSIHLYPPEASEASYSRHPSYESQGHVELTRPVHALYRNHELRATESDGSLLIGRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP94</accession>
    <name>W6ZP94_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Kynureninase</fullName>
            <ecNumber evidence="4 5">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Biosynthesis of nicotinic acid protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BNA5</name>
        <name evidence="8" type="ORF">COCMIDRAFT_1969</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>L-kynurenine + H2O = anthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the kynureninase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="4 5"/>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684160.1">
        <property type="nucleotide sequence ID" value="XM_007685970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZP94"/>
    <dbReference type="STRING" id="930090.W6ZP94"/>
    <dbReference type="GeneID" id="19119973"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1969"/>
    <dbReference type="eggNOG" id="KOG3846">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_4_0_1"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00329"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00334">
        <property type="reaction ID" value="UER00455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097053">
        <property type="term" value="P:L-kynurenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000031">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084:SF0">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22580">
        <property type="entry name" value="KYNU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="7">
        <location>
            <begin position="121"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="171"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="505" mass="56521" checksum="8C15E45C6607E3F0" modified="2014-04-16" version="1">MPYGHNPYLAIPEPELRAEQFARREDEKDGLSKLRNEFVIPTKGDLRNRNYGFQRKEKNPSAQSDDNEESIYFCGNSLGLQPRRTKEYVNRYLDTWASKGVFGHFTNYEGGLPPWLHIDDAAKNQTAKIVGAHPSEVVVMETLTANLHLLMASFYRPTKDRWKIIIEGKAFPSDHYAALSQIAHNNLDPSALITIDPPSSSSPYLSSEHILSVISHHAPSTALVLLPGIQFYSGQFFDIELITRHCRSLGITVGWDLAHAIGNVPLKLHDWNVDFAAWCNYKYMNGGPGTIGGLFVHERHSKVERAPTPRTNGTGSTSENGAQLSYRPRLSGWWGSDKSSRFHMDNQFVPIPGASGFQLSNPSALDMTSVMASLDVFALTDMEALRERSLRLTAYLEARLLKYPNGEPPYKIITPVNPMERGAQLSVLLNPGLLDKVQHYIEERGVVVDERKPDVLRVAPAPLYNSFHDIHRFIIIFHEACQMALKSGGRTTSYNDAVPRGIATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQH2</accession>
    <name>W6ZQH2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Translation initiation factor IF-2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_83804</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683818.1">
        <property type="nucleotide sequence ID" value="XM_007685628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQH2"/>
    <dbReference type="STRING" id="930090.W6ZQH2"/>
    <dbReference type="GeneID" id="19126335"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83804"/>
    <dbReference type="eggNOG" id="KOG1145">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006301_8_5_1"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03692">
        <property type="entry name" value="mtIF2_IVc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000008">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10050:FF:000001">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000019">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF20">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="430"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="110"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="204"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="722"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC49749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="958" mass="105642" checksum="61F7F536B79104CB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQU1</accession>
    <name>W6ZQU1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_93816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963972">
        <property type="protein sequence ID" value="EUC46066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687426.1">
        <property type="nucleotide sequence ID" value="XM_007689236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQU1"/>
    <dbReference type="GeneID" id="19128333"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93816"/>
    <dbReference type="HOGENOM" id="CLU_2489288_0_0_1"/>
    <dbReference type="OrthoDB" id="10281745at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="87" mass="10151" checksum="77C5A91186956639" modified="2014-04-16" version="1" fragment="single">PICVDDRVRRPIYAAYEAAPCPLVLSNYAGPAKQFCLKIERRAGTTEPIGELDSQPRDLEKPKWERRLRLHIHIRVLEEGLWGAWQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRV9</accession>
    <name>W6ZRV9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_92810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type III membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OST4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687058.1">
        <property type="nucleotide sequence ID" value="XM_007688868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRV9"/>
    <dbReference type="STRING" id="930090.W6ZRV9"/>
    <dbReference type="GeneID" id="19128151"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92810"/>
    <dbReference type="eggNOG" id="ENOG502SZVF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160806_1_2_1"/>
    <dbReference type="OrthoDB" id="2124077at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018943">
        <property type="entry name" value="Oligosaccaryltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051307">
        <property type="entry name" value="OST4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036330">
        <property type="entry name" value="Ost4p_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48164">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48164:SF1">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10215">
        <property type="entry name" value="Ost4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103464">
        <property type="entry name" value="Oligosaccharyltransferase subunit ost4p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC46436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="50" mass="5491" checksum="46DF0221F57798EB" modified="2014-04-16" version="1">MITDSQLYSLAIFLGSAAMLLIVVYHFLEVNSEDHKVEEKPRAAGGKVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSM8</accession>
    <name>W6ZSM8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thioredoxin peroxidase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thioredoxin-dependent peroxiredoxin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_22121</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683006.1">
        <property type="nucleotide sequence ID" value="XM_007684816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSM8"/>
    <dbReference type="STRING" id="930090.W6ZSM8"/>
    <dbReference type="GeneID" id="19120188"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22121"/>
    <dbReference type="eggNOG" id="KOG0541">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072440_1_1_1"/>
    <dbReference type="OrthoDB" id="195498at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000020">
        <property type="entry name" value="Peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="4"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="8">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00079296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC50524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="167" mass="18152" checksum="27C073237A1E6765" modified="2014-04-16" version="1">MAPLKVGDKLPEGVKFEWAPITDSDPTACGRPQEYDASKEWADKKVVVFSVPGAFTPGCQAYHLPPYIAKAKEFKDKGVDIIATIASNDAWVMNAWGKVNGVKGDEVLFLSDTKTFFSKNHGWDAGMGDRNGRWAMVFDHGKVIYAENEKSPGEVSVSGADAVLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZT83</accession>
    <name>W6ZT83_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL32m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_91557</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686596.1">
        <property type="nucleotide sequence ID" value="XM_007688406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZT83"/>
    <dbReference type="STRING" id="930090.W6ZT83"/>
    <dbReference type="GeneID" id="19127904"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91557"/>
    <dbReference type="eggNOG" id="KOG4080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1511123_0_0_1"/>
    <dbReference type="OrthoDB" id="2014905at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051991">
        <property type="entry name" value="Mitoribosomal_protein_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="140"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC46931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="178" mass="20340" checksum="0EFA54668603CA8D" modified="2014-04-16" version="1">MALARPLPPLWQTLLPGLNASTRPILNAPFLQRLVQPFGALNTPFGALAIPSLSLPKIPSLADIWDGILNAVPKKKTSYRKKRQRFMAGKGLKDITSLNRCSACGRVKRLHILCPYCVDAIKTNIFGQLNWAIRRPTDKQAKQWARERRSEAQRKRTMLPDPRKEKEEQILKHTGWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZV85</accession>
    <name>W6ZV85_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_34901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685851.1">
        <property type="nucleotide sequence ID" value="XM_007687661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZV85"/>
    <dbReference type="STRING" id="930090.W6ZV85"/>
    <dbReference type="GeneID" id="19122664"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34901"/>
    <dbReference type="eggNOG" id="ENOG502SA5E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086075_1_1_1"/>
    <dbReference type="OrthoDB" id="5422320at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024526">
        <property type="entry name" value="DUF3807"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40642">
        <property type="entry name" value="YALI0F31295P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40642:SF1">
        <property type="entry name" value="YALI0F31295P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12720">
        <property type="entry name" value="DUF3807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="211" mass="23915" checksum="48C0E5753ACAC99C" modified="2014-04-16" version="1">MALQIPTVTVDDLLAFHAQHFPHASTPEHILYGVNHEPETAEEYYDEEDDGLGYYPDGTKRTLTDEQIAMFRHSEIQAILRKRRLQKENGESSDCKSTAEKLSPDVASPAQEGSSHMADDSQQAQGKESGQANKQQWATTSAKSKAKAKRKRDRYAKRRREVRLQKGLPRRRSGRNGPGSDYSDDESDEWDPWHQANGPDAQKDDTLDLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZXH9</accession>
    <name>W6ZXH9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial import inner membrane translocase subunit TIM17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_87046</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684991.1">
        <property type="nucleotide sequence ID" value="XM_007686801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZXH9"/>
    <dbReference type="STRING" id="930090.W6ZXH9"/>
    <dbReference type="GeneID" id="19126973"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87046"/>
    <dbReference type="eggNOG" id="KOG1652">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087811_3_0_1"/>
    <dbReference type="OrthoDB" id="2261329at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC48571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="16840" checksum="4DB0988B06386644" modified="2014-04-16" version="1">MDHSRDPCPWVILNDFGGAFAMGAVGGAVWHGVKGFRNSPYGERRIGAITAIKARAPVLGGNFGVWGGLFNTYDCAVKGIRKKEDPWNAIIAGFFTGGSLAVRGGYKSMRNGAISCAILLAVIEGVSIGFNRMMADNTRLDAPPPPPSDAGASPGSGGMAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0J6</accession>
    <name>W7A0J6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cleavage and polyadenylation specificity factor subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cleavage and polyadenylation specificity factor 100 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_1603</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683827.1">
        <property type="nucleotide sequence ID" value="XM_007685637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0J6"/>
    <dbReference type="STRING" id="930090.W7A0J6"/>
    <dbReference type="GeneID" id="19119904"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1603"/>
    <dbReference type="eggNOG" id="KOG1135">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Schackwitz W."/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="307" mass="34168" checksum="C70908EAAE989CC4" modified="2014-04-16" version="1">MLPPVDPALLQRNPNFEILYKDLCTRKLNPNGSTRETKKQRVHDEIRRALSAARTSLLTTQILIDTLSDLPSKAADLPPELHSLIDIATAQLRGQIPSSDREILSTDLEAFMTNSDIISESLSTLLTKTTSYLCKIADPLNPPSPQDLSARANTLQTDATLTLPDELQTAHLNLTHSFTVLLATHSTLLTTAIKILEQTQQGALARHTRSSADLLHARSVLLGLQAKIHTYSHPPPAEFVDALRQFKKSQGSGEKALRDREALARQELQLYERAGEKGMRELARRKEWILAEVARVEEEVRKLERGG</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="LaButti K."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
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    </dbReference>
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        <location>
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            <end position="16"/>
        </location>
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            <end position="267"/>
        </location>
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            <end position="254"/>
        </location>
    </feature>
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            <begin position="200"/>
            <end position="252"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="26592" checksum="6C55F1A6FCAA180C" modified="2014-04-16" version="1">MKGFVLSLVFAATAAALPGASFKTAGKLPAIKRNPLRRASQIIPVVVGGPQDTFVPNSITAAVGDIVQFQFSNGNHTVTQSTADTACTPMDGGVHSGHIPFQDGQTEVGTFNMPITSTEPMFLYCATGPHCQLGQVMMINPANATQLAEYTKKSQQSAASVDGTNVVGGTPGKLALEAAAFVPAPPEDAGAGGPPPAGTPPAAEAPPAAEAPPAAEAPAAEAPAASPTASAAPEAPAEAPAAETSAAAAPATIVVHPAKRGFQGRMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4G7</accession>
    <name>W7A4G7_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
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        <name evidence="2" type="ORF">COCMIDRAFT_254</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="68"/>
        </location>
    </feature>
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        <location>
            <begin position="127"/>
            <end position="184"/>
        </location>
    </feature>
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        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC51031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="598" mass="67027" checksum="E71724C7215B5B85" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W7A541</accession>
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            <fullName evidence="4">Beige protein homolog 1</fullName>
        </recommendedName>
    </protein>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="3">May be involved in protein sorting and cell wall formation.</text>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Alfy-like_Arm-like"/>
    </dbReference>
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        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051944">
        <property type="entry name" value="BEACH_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
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        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
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        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108:SF4">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arm_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="8">
        <location>
            <begin position="1829"/>
            <end position="1963"/>
        </location>
    </feature>
    <feature type="domain" description="BEACH" evidence="7">
        <location>
            <begin position="2002"/>
            <end position="2295"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="2427"/>
            <end position="2468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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            <end position="1176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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            <end position="2303"/>
        </location>
    </feature>
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        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="976"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00054699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00073334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC51216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="2628" mass="295365" checksum="849CC33D5011E3FD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>W7A5J6</accession>
    <name>W7A5J6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">sterol 3beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.173</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Autophagy-related protein 26</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_21394</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a sterol + UDP-alpha-D-glucose = a sterol 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22724"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15889"/>
            <dbReference type="ChEBI" id="CHEBI:37424"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.173"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:22725"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ergosterol + UDP-alpha-D-glucose = ergosteryl 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61836"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16933"/>
            <dbReference type="ChEBI" id="CHEBI:52973"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:61837"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.173" evidence="4"/>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682111.1">
        <property type="nucleotide sequence ID" value="XM_007683921.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W7A5J6"/>
    <dbReference type="GeneID" id="19120052"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21394"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_6_0_1"/>
    <dbReference type="OrthoDB" id="10261837at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13215">
        <property type="entry name" value="PH-GRAM1_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13216">
        <property type="entry name" value="PH-GRAM2_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000303">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000029">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048066">
        <property type="entry name" value="ATG26_PH_GRAM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048065">
        <property type="entry name" value="ATG26_PH_GRAM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF25">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="14">
        <location>
            <begin position="293"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="465"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="548"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="590"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="652"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="685"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC51426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1461" mass="164088" checksum="2676AB19C1E006BC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLS2</accession>
    <name>W6YLS2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ent-kaurene synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_30863</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964192">
        <property type="protein sequence ID" value="EUC40157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693331.1">
        <property type="nucleotide sequence ID" value="XM_007695141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLS2"/>
    <dbReference type="STRING" id="930090.W6YLS2"/>
    <dbReference type="GeneID" id="19121760"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30863"/>
    <dbReference type="eggNOG" id="ENOG502QQN6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005861_0_0_1"/>
    <dbReference type="OrthoDB" id="2343925at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010333">
        <property type="term" value="F:terpene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016102">
        <property type="term" value="P:diterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017057">
        <property type="entry name" value="Ent-kaurene_synthase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050148">
        <property type="entry name" value="Terpene_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31739:SF25">
        <property type="entry name" value="(E,E)-GERANYLLINALOOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31739">
        <property type="entry name" value="ENT-COPALYL DIPHOSPHATE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036498">
        <property type="entry name" value="Ent-kaurene_synthase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">ATCC 44560</strain>
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        <location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="3">
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        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51782"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40442.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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    <accession>W6YN10</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="110" mass="12433" checksum="73E88101BDD16092" modified="2014-04-16" version="1" fragment="single">TVRVWETATGHCRTVLENQPSPIFHIAFSRDGRTLHTDNGDIPLLLDLIAVASVLPAQELPYATVKDEWVLRQTRRFLWLPPQYRDCVAAVYRHTVCLGSHSGHVALLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YN85</accession>
    <name>W6YN85_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC40772.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="54868" checksum="73CC38A8A0CDD30D" modified="2014-04-16" version="1">MKICVVTPSPASGAEATVQPDLASYIDQEVHSVQKRQIRKEHAIEDIDELEIGNFDVFINYLTNDCFVHFMQQPIDHEWIKALKYLNSKYLFGIGRLPDSALDLYAANLERAQTSDSQGDEQPPPTALLLPNQAQELQDGDYSILVVLFGRTASALTPLKYQAAVKDGQEATWVLAPESDLSRRLQETAVSAFEQVRGTEYLGYLTVNIRVAEASDTPIVTNVDPTTRFFYPQGVTPWDSLVIAKTLPGGHAAFFETLLSTRLAKVPHYVMRNEGCARQHDRLARLYYTILDSTNVTDNRLSPFVGKYDYNGTVLDCCSGSGEFARFAIDHGVKAKYSALDYSVEMTKLPFSKTLYEQPFILGPVQEVLASAPMHDHVVCFGSMHLLQPFDFISTISQMFLRAKKSVTFDVDDLSDTYINNFPDASSEKCWEKLEYNHNHTARIFRFGTPVGWKAVMYGERRFAYKSLVMKEDVYTHSFRFERIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPA0</accession>
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        <recommendedName>
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            <taxon>Dothideomycetes</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the aldehyde dehydrogenase family.</text>
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    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="KI964115">
        <property type="protein sequence ID" value="EUC41182.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPA0"/>
    <dbReference type="STRING" id="930090.W6YPA0"/>
    <dbReference type="GeneID" id="19121599"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29981"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_1_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006598">
        <property type="term" value="P:polyamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000050">
        <property type="entry name" value="Aldehyde dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000012">
        <property type="entry name" value="Betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720:SF3">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE ALDH (AFU_ORTHOLOGUE AFUA_8G02310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="491" mass="53127" checksum="1FCE0617B0B628CD" modified="2014-04-16" version="1">MAEPINLTAPNGVQWTQPTAAPGLFINNEFVAAKSRETLKTINPYDESVISEVAAARAAYKSSEWRDISAVERGSLLWKLGELCEQNAQILATIDAWDNGKPYQQALDEDVSETISVFRYYAGWADKVYGQTIETSKEKLAYTKHEPLGVCGQIIPWNFPIMMAAWKLGPALACGNTVVLKPAEQTPLSALFLASLIKKAGFPPGVVNTVNGDGRIAGAAHLPAHPGVDKIAFTGSTVTGRAIMRAAAGSLKNITLETGGKSPLLVFDDCDLEQAVRWSHMGVMGGMGQVCTSTSRLYVQDTIYERFLEAFKNHTKENTNIGSQFDANVNHGPQISKAAQDRIVNYIQIAKSEGAELIYGGDQANIPSKGYFVGPTAFANVTNDMKVVREEIFGPVVVIQSFKTEEEAIEKANDSDYGLGAAVFTKDIMRGHRVAGSIEAGMVWINSSQDSHFGVPFGGYKQSGIGRELGQYALSSYTQVKAVHVNLGTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPK9</accession>
    <name>W6YPK9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_55355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964316">
        <property type="protein sequence ID" value="EUC39595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693884.1">
        <property type="nucleotide sequence ID" value="XM_007695694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPK9"/>
    <dbReference type="GeneID" id="19124647"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_55355"/>
    <dbReference type="eggNOG" id="KOG0505">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2339058_0_0_1"/>
    <dbReference type="OrthoDB" id="3679171at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24124">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24124:SF14">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_25, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="98" mass="10496" checksum="6BB12B6774918450" modified="2014-04-16" version="1" fragment="single">LLRLGATTDTCDQAGRYPIHFAAVGSTTANFAALRDANANLYARDNAGRTLVHFAIVSGNMDLLLCVLQATTGLLHQPDADGWTPLHYAATFHNLSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQS5</accession>
    <name>W6YQS5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_29480</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964086">
        <property type="protein sequence ID" value="EUC41782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691687.1">
        <property type="nucleotide sequence ID" value="XM_007693497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQS5"/>
    <dbReference type="GeneID" id="19121511"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29480"/>
    <dbReference type="eggNOG" id="KOG4561">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034597_0_1_1"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="8">
        <location>
            <begin position="69"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="365"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC41782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="392" mass="44617" checksum="AB4E056856E494DF" modified="2014-04-16" version="1">MHDPFPIARPESLVKYVQPVADYLSLNTLPLHFHEIAAAYVLYDVTYRFVAPAFSRIFFPRVYATFNARTKLNWDVHIVSFVQSTLICALALWVMWTDKELNSMDRAERVHGYTGASGLIQAFAGGYFLWDLVITVQNVKIFGIGMLFHAISALCVFSLGFRPFVNYYTCTFILYELSSPFLNIHWFCDKLNMTGSTLQFVNGLMLLFTFFSCRLVWGTYQSIRVFGDVYHLYMNGYVPQPDPEVGKLSDDTYVNNAGFKNDLLQYSAGQTTPLWLISAYLASNLILNGLNWFWFSKMIETLRKRFDPPIGTRKVQPKVSATPVEISENEKVLIEGIHVSTPGVIEKDTEDYVNVASPKSLQFQKNKSGTHLEVKQSEVRSRNPSQRAAHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQZ4</accession>
    <name>W6YQZ4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_31029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964221">
        <property type="protein sequence ID" value="EUC39928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693555.1">
        <property type="nucleotide sequence ID" value="XM_007695365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQZ4"/>
    <dbReference type="GeneID" id="19121791"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31029"/>
    <dbReference type="HOGENOM" id="CLU_789858_0_0_1"/>
    <dbReference type="OrthoDB" id="10574223at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="351" mass="38808" checksum="910761F91FCECA8E" modified="2014-04-16" version="1">MSNAAIITCSVFVTAVRAPQAVRLVVQSSASPAICLAFVAYILPIMPCIASIILATQGLTAYGLQVHVFTLYSLAWIDWMYIDKWFAGMTQHEWSELPRPKLSQQWLCRIGVVIGYIVSGCVVLYLHNAYANLATLLVFSGSYVYLSIQPWPQAFQREGMAWLRHYQIAFTVVLVMASIALSVVLIIASTVSTVGAILLQKIAVSFPTWLPIIRRTKPTQNHFGVGNSPYGWRNVGGSEESMWHRRVETLEQLLIVLGAESDDKKIGNGVMMRMADTDKALFLLCIQCSERLDFSSTKEFLSACSDGTLDGSRLAEPLRHLGSSHIKTAEFAALLNKLKRTHSAVLAEVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTB6</accession>
    <name>W6YTB6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964053">
        <property type="protein sequence ID" value="EUC42677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690803.1">
        <property type="nucleotide sequence ID" value="XM_007692613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTB6"/>
    <dbReference type="GeneID" id="19121368"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28751"/>
    <dbReference type="eggNOG" id="ENOG502R6R8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_987534_0_0_1"/>
    <dbReference type="OrthoDB" id="3712212at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="280" mass="31405" checksum="C2F3649FC5CF345D" modified="2014-04-16" version="1">MDFSSSAFRSAPTSKVSDDVMSHANLVMACRWGWTSSPSAESGGANSPFATSTQPSSSASTFNNVRSKRFAPCQGRLYHQLLCSHRIRTDLVEDCGANCVEPYGNTVEAAFICHECIQAEATKIWEERQAQHNALYPSIEQMSQEQYDQWYAEHRQLEADFSRDQRVYEMELKAKTRPSNICSAMEASKEEMEFANELDSLSLSLMTSNTSTADPAPLQVQNRTRTSLATDPEEQLHWDLNTLALDRGSCGIEYSASQPNNGVKSPRQLDAEELWRKPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTP5</accession>
    <name>W6YTP5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_30244</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964132">
        <property type="protein sequence ID" value="EUC40903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692578.1">
        <property type="nucleotide sequence ID" value="XM_007694388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTP5"/>
    <dbReference type="STRING" id="930090.W6YTP5"/>
    <dbReference type="GeneID" id="19121646"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30244"/>
    <dbReference type="eggNOG" id="KOG0710">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_1_1_1"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="34"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="195" mass="22539" checksum="378B7375C65E58ED" modified="2014-04-16" version="1">MSLFPRFTQEFAPMFRLFDEYDRQAFRNIDRQFESVRSFTPKFDVKETKDAYELHGELPGVEQKDVNIEWTDNNTLTISGRHEHVREEGQRPQGFIESGDKSDQKKLGHQPKVEDDTSESNNKVAKQSQEKGVTKHDDTQAKYWVSERSVGEFHRSFAFPARVDQDNVKASLKNGILSIVVPKAQAPQPRKINIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUL2</accession>
    <name>W6YUL2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-dependent oxidoreductase 2 FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_63540</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI964038">
        <property type="protein sequence ID" value="EUC43157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690345.1">
        <property type="nucleotide sequence ID" value="XM_007692155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUL2"/>
    <dbReference type="STRING" id="930090.W6YUL2"/>
    <dbReference type="GeneID" id="19124935"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_63540"/>
    <dbReference type="eggNOG" id="ENOG502SM6C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011398_4_4_1"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005511">
        <property type="entry name" value="PRK07121.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF10">
        <property type="entry name" value="3-OXOSTEROID 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="5">
        <location>
            <begin position="10"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC43157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="421" mass="46260" checksum="F542D1B847388D97" modified="2014-04-16" version="1" fragment="single">STDAKTREADVVVVGAGVAGVCASIAAAEKGASVILIDASHGGGASALSGGVVYAGGGTVQQKAAGYGHDTPENMFTYLKEETQDAVDEETLRRFCKTSAQNLQWLEKHGARFEASLCPYKTTYPTDRHYLYFSGSEEAYPYNKIADPAPRGHRMVHPGLSGSELWRVLFKSAVGLGVDFMPVSKVTRFLRDKNQRINGVETKTLPKSSPSFTRHKSLSKKEKQYQMSLRPVSKWYHNRALNLWNRDAHLQTLHAPSIILAAGGFSFNPHMRQTHMPEYSNVAPLGTWRDDGSGIALGTSAGASVAKLDRMSAWRFIYPPTALLEGIAVSASGRRMLAEDVYGAALGGIMIQRHAGRGFLILDRTQWRKARQQLFQQTSGPVLMQRFHWMYWGYKKAGSLAGLAAKFGIAARGLEETVREY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV90</accession>
    <name>W6YV90_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Non-structural maintenance of chromosomes element 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_106080</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the SMC5-SMC6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NSE4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964101">
        <property type="protein sequence ID" value="EUC41463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692006.1">
        <property type="nucleotide sequence ID" value="XM_007693816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV90"/>
    <dbReference type="STRING" id="930090.W6YV90"/>
    <dbReference type="GeneID" id="19118798"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106080"/>
    <dbReference type="eggNOG" id="KOG2866">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041037_4_0_1"/>
    <dbReference type="OrthoDB" id="361242at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027786">
        <property type="entry name" value="Nse4/EID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014854">
        <property type="entry name" value="Nse4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029225">
        <property type="entry name" value="Nse4_Nse3-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16140">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16140:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15412">
        <property type="entry name" value="Nse4-Nse3_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08743">
        <property type="entry name" value="Nse4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nse4/EID protein Nse3/MAGE-binding" evidence="10">
        <location>
            <begin position="207"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Non-structural maintenance of chromosome element 4 C-terminal" evidence="9">
        <location>
            <begin position="402"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="307"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF15412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC41463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="507" mass="56937" checksum="A59A13AFE42181B0" modified="2014-04-16" version="1">MARLNTHLSATPQTRASTVDSLYRDPSVVPRAEQNGCTSSYSVISPTRSINSDKENESPATRDNTPRRGKSRGLRVASARMPTPDSGSTEGNGSKRRRTDNYTMSRSQIYDDEQDADQDDEEDGIDTPSQSHVQPEQEEEGHLRFYNPNQDPEKRRRLRATMRDHQRMLDDNRDDLIKAHDSGLLDALRTQNSLFGKVRQTADATVDSRFLVNASDLAGKKLNNALGNYSAGIDLDQFVSKCMYFMKSGGYVAGDEDAPTMPVGDDEDDDPDGLDWAMLGRRACFPCNKRPPTASFLLGPLSVQKRIRSATQRRARSQRQPVGPATRPQEIKEGDIQQNENNNLSNLVKGIRKRLIDHTKQGADRVESELSEIPESEMDDESQNAAFRRYRMAMTTDGEPAVNLLDFVINPHNFGQTVENLFYISFLVREGNAKIVKDDNGLPLLVPAAPRGVSEQREDNVQKHQAVFSLDYPTWRMFIDAYDIKEPLIPHRESQEANVGSNGWYNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX96</accession>
    <name>W6YX96_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycoside hydrolase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_99260</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964013">
        <property type="protein sequence ID" value="EUC44022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689447.1">
        <property type="nucleotide sequence ID" value="XM_007691257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX96"/>
    <dbReference type="STRING" id="930090.W6YX96"/>
    <dbReference type="GeneID" id="19129431"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99260"/>
    <dbReference type="eggNOG" id="KOG2024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009935_3_1_1"/>
    <dbReference type="OrthoDB" id="408320at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051913">
        <property type="entry name" value="GH2_Domain-Containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42732">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42732:SF2">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886370" evidence="4">
        <location>
            <begin position="21"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolases family 2 sugar binding" evidence="7">
        <location>
            <begin position="118"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="5">
        <location>
            <begin position="233"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 catalytic" evidence="6">
        <location>
            <begin position="360"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="658" mass="73939" checksum="8DBB9165BCD25A09" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXB8</accession>
    <name>W6YXB8_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_104239</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964071">
        <property type="protein sequence ID" value="EUC42160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691334.1">
        <property type="nucleotide sequence ID" value="XM_007693144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXB8"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_104239"/>
    <dbReference type="eggNOG" id="ENOG502QRM1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024934_0_4_1"/>
    <dbReference type="OrthoDB" id="4937900at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC42160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="409" mass="46657" checksum="B736C26B1A9B021C" modified="2014-04-16" version="1">MTEKEKEKRVAKRKTHTKSRRGCFQCKQRHTKCNEARPRCANCVRLDIHCTFPTIPESYTSSPQHSPGVSSSYGDVGLPESPDVSHSHAGSDLPLADLQLLHHWIKSCAKSLHPNPSLRSSAWQTEFVELGFEFPFLLRGFLALSAVHQAFLLPPNDRQVLLLQADSHISRALDTYRKNLEIPDVKLALPMFMLSSVLFTYNFGSAQLQQPEDPIAALHHCFMLLQGIKIVVMPHWHQIKDSAFVAYMTDTPSDDLLKGLDNLASQDNPQEIMRLKELTELLLDSQDKVACTVAIDELHTTWLRFRHLPADRDEYSLLFYWPALLESRFLELLAAHNPVTCIITTHFVAMLAQSRPVWWVGKWPQWLLTASEQLLAATPDLLKWLEWPRKMIRPQGWSIASTLSDRQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXC6</accession>
    <name>W6YXC6_COCMI</name>
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        <submittedName>
            <fullName evidence="5">Carbohydrate-binding module family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_104206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964070">
        <property type="protein sequence ID" value="EUC42178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691301.1">
        <property type="nucleotide sequence ID" value="XM_007693111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXC6"/>
    <dbReference type="GeneID" id="19118463"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104206"/>
    <dbReference type="eggNOG" id="ENOG502TF6B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1686256_0_0_1"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886211" evidence="3">
        <location>
            <begin position="20"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="4">
        <location>
            <begin position="95"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="141" mass="15357" checksum="A6C8765F0EBFC648" modified="2014-04-16" version="1">MYLTTVAILYAGLLTLCGAVPADNKAQLEPRQTYIITCIGGRCSDNISRPTSEPPKPTSSKLMNSSQTTIKTSTKTVVPPTKTTTEEVGPSSTRCPVPLYYKCGGWHDGKPWTGCTQCVKGVKCVEQNEWYFQCVADNSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXY5</accession>
    <name>W6YXY5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_72116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964167">
        <property type="protein sequence ID" value="EUC40419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693063.1">
        <property type="nucleotide sequence ID" value="XM_007694873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXY5"/>
    <dbReference type="GeneID" id="19125217"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_72116"/>
    <dbReference type="eggNOG" id="ENOG502S62N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013929_2_2_1"/>
    <dbReference type="OrthoDB" id="5425161at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF74">
        <property type="entry name" value="POGO TRANSPOSABLE ELEMENT WITH KRAB DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="1">
        <location>
            <begin position="78"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="247" mass="28137" checksum="CBD0A05A6A55673C" modified="2014-04-16" version="1" fragment="single">MADRLLAARGAGQVGVHWPRNFSWFELIEQTKAKYGICNEDVYNFDEAGFSIGKITTQLIVTASERRGRPKAVEPGNREWVTFIAGINAAGWAIPPFLIFTGKHHLSAWYEEAEIPRDWAIAVSDNGWTNNELGVAWIKHFDTHTKTRVVGTRRLLILDGHESHQSLEFQEFCKDNNIYTLCMPPHSSHLLQPLDIGCFSPLKRAYSREVESLIRHHINHITKLEFLPTFKTAFDRSFTPANICSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY81</accession>
    <name>W6YY81_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964058">
        <property type="protein sequence ID" value="EUC42530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690951.1">
        <property type="nucleotide sequence ID" value="XM_007692761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY81"/>
    <dbReference type="STRING" id="930090.W6YY81"/>
    <dbReference type="GeneID" id="19123685"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39424"/>
    <dbReference type="eggNOG" id="ENOG502SQZ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1461824_0_0_1"/>
    <dbReference type="OrthoDB" id="5241710at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="199" mass="21615" checksum="C74B07DBF3AD3347" modified="2014-04-16" version="1">MLNFTFFTLSTYHALRAISVATFPPGFLILFLQGILSRCVNPAIGIIPFFFSAAYSALILANEKICGCQSSVLTGTLMHLVSDLLLGIALLACLILDWVFIPQGGTDRGLVMLGTYGTTFLICNLLIHFYFAINRIVEELQPGTYYPTSCPQCQGKSFSFRMYKLNSEIFSGYASLLDGEGRPKNGARLAVVGEGGSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYB7</accession>
    <name>W6YYB7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_108539</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964156">
        <property type="protein sequence ID" value="EUC40554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692939.1">
        <property type="nucleotide sequence ID" value="XM_007694749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYB7"/>
    <dbReference type="STRING" id="930090.W6YYB7"/>
    <dbReference type="GeneID" id="19119267"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108539"/>
    <dbReference type="eggNOG" id="ENOG502QTW1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027360_0_0_1"/>
    <dbReference type="OrthoDB" id="5356836at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF5">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="332" mass="37551" checksum="286D78F7BE61C1D7" modified="2014-04-16" version="1">MQRTVVTINSNGRQSASFIRVAAALGWQVRAQMRDLNGIVARELSELDNVTVFIGALEDKKFLDDLFRSAQCAFINTTHWGDEVAIGRSLADAAKKAGIQHYIYSSMPDHSVFGQGWKALPMWAPKFTVEQYVRQIGLPATFVYCGAYHNNFTGLDFPLFRMEHQHDGSFVWQAPFHPDQPLPWLDSEHDVGPAIFQLFKEGPRKWNGKRIPLAFASMTPRQVCKAFSVGLKRPVRYKRGPIMINVPTPAGYREHLAALEYTLGEKGAPYFGPDLEPDVPAVALSLWEGNRSMEEYAQEVFPVEEAANGLTWMEEVETPRREIEIDFEQINC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYF9</accession>
    <name>W6YYF9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_108367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964152">
        <property type="protein sequence ID" value="EUC40599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692877.1">
        <property type="nucleotide sequence ID" value="XM_007694687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYF9"/>
    <dbReference type="GeneID" id="19119229"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108367"/>
    <dbReference type="eggNOG" id="ENOG502QVK9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1758493_0_0_1"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="62"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="148" mass="16224" checksum="FE3666BE9626FF55" modified="2014-04-16" version="1">MPGSTSLCSLECAPPLSDSGQRAFEGETTATPAPRKLGRPLWQRTPATSADSSVTSNSVRQTTCVRHTQVERKYRESINMRLERLRRAVATLPQAVGADAIGVAKPSKGIVLAAAIDYVGRIERERDAAMDEIERLAGDVRTRQLERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ35</accession>
    <name>W6YZ35_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Caspase family p20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_97663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688847.1">
        <property type="nucleotide sequence ID" value="XM_007690657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ35"/>
    <dbReference type="STRING" id="930090.W6YZ35"/>
    <dbReference type="GeneID" id="19129104"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97663"/>
    <dbReference type="eggNOG" id="ENOG502STT9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067131_0_0_1"/>
    <dbReference type="OrthoDB" id="3688820at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="39743" checksum="DA2016B9E1DA76C0" modified="2014-04-16" version="1">MSGPAPPHAWKDPKKASAETFQTELETAVISGIGYRIRRDYKKMSAVLIHSEDDTGCDDLEEQLAETLRNFYSIDNIKRLLLGNGNPYLAISRVINELADTGYTGKGCLVILVFASQGQVHSKANTDPFRGPEDRLVFGADGNSRTRGFDWKTATFALSEEDCEILHIMDCCYAEDMEADAEVLAAATETISADGNKCFVKALITALRDFAPEPFSIYSLHQALVLNRTDLNLECIPFYQKRENRSSIVLGGWTGQVPAHKPDSPRILLTVHIEEDLNMRDIEDWKEWLEDLLPRSVMNMEIKLEGVWNAWSSVLLISLPISVWTQLDRCNTALHYVGQVTSHNRLLEQVAPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZL7</accession>
    <name>W6YZL7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964042">
        <property type="protein sequence ID" value="EUC43028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690461.1">
        <property type="nucleotide sequence ID" value="XM_007692271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZL7"/>
    <dbReference type="STRING" id="930090.W6YZL7"/>
    <dbReference type="GeneID" id="19121316"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28465"/>
    <dbReference type="eggNOG" id="ENOG502QV1J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023620_6_0_1"/>
    <dbReference type="OrthoDB" id="5595695at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.520">
        <property type="entry name" value="Amidohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.90">
        <property type="entry name" value="Amidohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10910">
        <property type="entry name" value="Amidohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="53"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="416" mass="45765" checksum="49ED60BEB5D97FE9" modified="2014-04-16" version="1">MATFIIRDVRIFTGEEVIEEGYAHVQDGKIKSVGPIGSIPQESMKTYSKPGHTLLPGLIDCHIHADRADPVALPQSLRFGVTTVCEMHNELENVLKLRKQTLEPDTASYKTAGQAATIENGWPIPVITAHDKSEETAAAIARWPKLTDHTSVTNYLDWTTKEMQPDYIKLMHESGTIMSQNYAYPSISLQRTIITEARARGYLTVAHATCLQDTLDVLNAGVNGLTHTFCDHPPTQELIDAYKKNNAWVNPTLATLGSLTTEGVDLQHKFAHDPRVKGLIGEDRVGNMCRCMGFADKGKVEFAYQGVKALKDAGIDILCGSDAAGPAVGTAFGLTMHHELHLFVHKVDMTPMEALRSATSLVAKRFKFEDRGRLEEGLNADMLLVEGNPLEDIDATLNIRGVWREGKGCSVYAEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZT7</accession>
    <name>W6YZT7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_101713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690374.1">
        <property type="nucleotide sequence ID" value="XM_007692184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZT7"/>
    <dbReference type="GeneID" id="19117917"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101713"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="25372" checksum="501E642F50A4A23B" modified="2014-04-16" version="1">MGTYFLTGANRGIGLEFVRQLAANPSNTIIAGVRSKSIDLSDLHSLNSNNNIHIVECDVGSLDSLSGIEFRVAEILSKKSSNLDFLFNIAGINATSSDTSLTLDPKSMAEHMQTNVLGPAKIVQVLRRYLARGATVLNMSSGLGSLAVSSEITKCCTYSMSKAALNMLTVHQSKDLKGNGVKVVCMDPGWVKTRMGGEGAVLEVQDSVRNMLDVVANLKEADSGKFYRQDGEIVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0D1</accession>
    <name>W6Z0D1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_96282</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the avfA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963989">
        <property type="protein sequence ID" value="EUC45167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688301.1">
        <property type="nucleotide sequence ID" value="XM_007690111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0D1"/>
    <dbReference type="STRING" id="930090.W6Z0D1"/>
    <dbReference type="GeneID" id="19128819"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96282"/>
    <dbReference type="eggNOG" id="ENOG502SM0C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090039_1_0_1"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF37">
        <property type="entry name" value="OXIDOREDUCTASE MDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC45167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="262" mass="28812" checksum="E4633AA0560C8079" modified="2014-04-16" version="1">MVSYAVLGATGNCGTALLELLIKNTDAKVKAYCRNKDKLFRLVPEAANNPRVEVYTGSILDADLLGKAMYGCKAVFLTATTNDNVPGCHISQDLAHTVIKALEKTKSEGSQAPPMPRLVLLSSATIDPWISRKNPWVNAIVRRSAWHVYRDLELAEEFLRKHEDWVKCVYIKPGGLSVDVQRGHRLTLDDEESFVSYLDIAAGMIETAEDDEGKWENKNVGVVNAGGKAKFPKGTPKCIICGLLSYYFPFLHPYLPSGTGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0M5</accession>
    <name>W6Z0M5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_106717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964113">
        <property type="protein sequence ID" value="EUC41224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692244.1">
        <property type="nucleotide sequence ID" value="XM_007694054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0M5"/>
    <dbReference type="STRING" id="930090.W6Z0M5"/>
    <dbReference type="GeneID" id="19118911"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106717"/>
    <dbReference type="eggNOG" id="ENOG502QUK9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022730_3_0_1"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF129">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="40"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="473" mass="51566" checksum="3A7712EDB8770066" modified="2014-04-16" version="1">MRQERATLPTPTSSDSFWHSEPNEYLIGHRTTENLPAEADIVIVGSGITGASTARYLAEDERANGKSIVMLEAREACWGATGRNGGHCQPLLFDRSSDVARFELKNVAAVRFYIQDNNVPCEWRDVTGCRTFWNQAALKEVENELRHLRNVAPEIAAKVTVIKDKEELKKHRVAPDCLAATLSEGAASLWPYKLVTFILQKLVQDGRVNLQTKTPVTNITTSEGKHTLHTPRGTISSKTVILATNGYTSALLPHFADLIVPCRGEMSALFPPEGSTLLPNSYGMVAALGQPAHNDDYLVQRPFEGVPNPAGHLMFGGGRGAGNYPSLGISDDSFIDEGSAAYLRGALLKVLELDGKTEGLKELKAAAQWTGIMGYSRDNHPWVGKVPDRDGLWLCGGYTGHGMPNGTLCGKAIVDMVLAEIGGQDVGAVQAQMIQRGDIPKSYILTKERIDKTRRMLTVHQQEEQGVHMNGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z151</accession>
    <name>W6Z151_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_7118</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964029">
        <property type="protein sequence ID" value="EUC43423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690034.1">
        <property type="nucleotide sequence ID" value="XM_007691844.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z151"/>
    <dbReference type="GeneID" id="19125181"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7118"/>
    <dbReference type="eggNOG" id="KOG0059">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001640_2_0_1"/>
    <dbReference type="OrthoDB" id="8061355at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001344">
        <property type="entry name" value="Related to ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001345">
        <property type="entry name" value="Related to ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="367"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="825"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="986"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1025"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1059"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1089"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1128"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1169"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="473"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1237"/>
            <end position="1468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC43423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1612" mass="176209" checksum="BB9983DBEBA3EE8E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1P3</accession>
    <name>W6Z1P3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_100337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964023">
        <property type="protein sequence ID" value="EUC43638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689849.1">
        <property type="nucleotide sequence ID" value="XM_007691659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1P3"/>
    <dbReference type="GeneID" id="19117657"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100337"/>
    <dbReference type="eggNOG" id="ENOG502SXT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081899_0_0_1"/>
    <dbReference type="OrthoDB" id="2687452at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="226"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="288" mass="32165" checksum="E7F3B20B50B22304" modified="2014-04-16" version="1">MLAHHGSHGDAFGLLESPFPPKCISPGQPYLVPRKHPVPIRNTHQAHELRLITSPAAPAYRPSALGTVSINTSSRPKKTESVRPKQEQPPSPAMSGYSYSSSDQGSYSYQQQPPYQPGVPQYTQQQINAYYAQYQCYPPQPWQMIQDYYVEQPMGVTPAPYQEPVTGYESTEWQMQSTDMNLPTGQSHKRTWTCDIPSCTSSAHFTRLADLQRHQSTVHGVGTPEYPCHVARCNRVGEKGFTRRDHLVEHLRNFHHIDIPRRKPGERSAFPFGWPEGAGAGVGGGAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2A7</accession>
    <name>W6Z2A7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit F</fullName>
            <shortName evidence="4">eIF3f</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_40099</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit F family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964087">
        <property type="protein sequence ID" value="EUC41769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691714.1">
        <property type="nucleotide sequence ID" value="XM_007693524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2A7"/>
    <dbReference type="STRING" id="930090.W6Z2A7"/>
    <dbReference type="GeneID" id="19123810"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40099"/>
    <dbReference type="eggNOG" id="KOG2975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027018_0_0_1"/>
    <dbReference type="OrthoDB" id="25498at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071540">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3e"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08064">
        <property type="entry name" value="MPN_eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000019">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03005">
        <property type="entry name" value="eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027531">
        <property type="entry name" value="eIF3f"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF6">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="6">
        <location>
            <begin position="30"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="310"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="316"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="344" mass="37466" checksum="46B544AD34116054" modified="2014-04-16" version="1">MAENDSFLHLARPLGPAPLGAQPSTAPLNVAIQPQAVFSILDHALRRPADQERVIGTLLGTRSEDGTEIEIRNCYAVPHTETAEQVEVDMDYQKQMLALHLRANPREVLVGWYATSSDLNTFSALIQNFYSQQGDGTWPHPAVHLTVSTVPGQDIESKTYISAPIGVTAERAADSCLFIPVPHEIKYGEAERSGLELISSAKDSEDRSQEVMTDLDSLERAIQHVLDMLERVSTYVNNVLDEEAEPSSALGQFLMNALSLAPKVEPADIERDFNAHIQDVLVVSYLANTIRTQIDLSNRLATAALTMGGGDVLGGEGKKDGENRGKGGDRRGGGKGRQQREQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2E0</accession>
    <name>W6Z2E0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_6742</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fungal Na(+)/H(+) exchanger family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964017">
        <property type="protein sequence ID" value="EUC43878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689592.1">
        <property type="nucleotide sequence ID" value="XM_007691402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2E0"/>
    <dbReference type="GeneID" id="19125065"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6742"/>
    <dbReference type="eggNOG" id="KOG4505">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008635_5_1_1"/>
    <dbReference type="OrthoDB" id="5327978at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000015">
        <property type="entry name" value="Na(+)/H(+) antiporter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
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        <property type="entry name" value="NA(+)/H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
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            <end position="29"/>
        </location>
    </feature>
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            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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            <end position="230"/>
        </location>
    </feature>
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            <end position="283"/>
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            <begin position="304"/>
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        </location>
    </feature>
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            <end position="354"/>
        </location>
    </feature>
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        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
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            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
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            <end position="430"/>
        </location>
    </feature>
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            <end position="489"/>
        </location>
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            <end position="556"/>
        </location>
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    </feature>
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        <location>
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            <end position="521"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="587" mass="64673" checksum="D2A96362D39CC9E6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2Z3</accession>
    <name>W6Z2Z3_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_93750</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963971">
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <location>
            <position position="1"/>
        </location>
    </feature>
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        <source>
            <dbReference type="EMBL" id="EUC46122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="142" mass="13787" checksum="43D4CFB73F782872" modified="2014-04-16" version="1" fragment="single">ITPGPGMPSATGSTPTSGAIPNSITLGSAIIALTPGVSTTIGPSSDQTLVAITTNAAGSTLVTISSSGVAVTATVSAVPTTVTLPKTGFEASITNVARPGVVTSSRPLSTTSSKAMAVGNKKSEVGWWTSAMLGVVGLVLGF</sequence>
</entry>
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    <accession>W6Z330</accession>
    <name>W6Z330_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
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        <name evidence="8" type="ORF">COCMIDRAFT_104518</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17327">
        <property type="entry name" value="MFS_FEN2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000018">
        <property type="entry name" value="MFS transporter permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF24">
        <property type="entry name" value="NICOTINIC ACID PLASMA MEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="42"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="490" mass="54556" checksum="D2DE94B1CB78BFF6" modified="2014-04-16" version="1">MHDTKVTDGSLCEKDIQAESSEEIQIDPIAEKKLIRKLDLILSPMMVIVFLVAYLDRSNVGNAAIAGMNEDLNLTGNRLNVAVTLFYVTYIAFELPSSLLLKRLRPSRLIPFFIISWSAVIIGAAFVQSYASLIATRLLLGAFESGLFPCLTLYLSMYYRPLEQARRVSYLFVASALSGAFGGLLAYGLTNLHGARGLAGWRWLFLVEGLISIVVGFAMIFLLPDNFETAWWLNEDEKALLRARHEKERLYQGKSMTTDAMDKTEVKLAFKDPKLWLSAACQFCANTCSFGFSTFLPVIIRGFGYSSIRTQLLTVPVYIWASAVYLFIAFCSDYVNRRAYFMIPLALVTSVGYAMMLGVSMASTGVLYFATFVTATGIFCCVGLNVTWVINSNAGYFKRATAIGLQQAIGNSAGIMAGQIYRLSNSDGRYVIGHAISICAITIAACGYGIMYIVLRKINRKRERMTIEERIREIDSGKLGDRHPDFRYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3C0</accession>
    <name>W6Z3C0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_27438</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="HOGENOM" id="CLU_022195_0_0_1"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:iron ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="Cytochrome P450"/>
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        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome P450"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="59601" checksum="DD84A13E94CE908A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
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            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="317" mass="36490" checksum="ABD5B824D690526A" modified="2014-04-16" version="1" fragment="single">WSREIDPSHLWPFYEDVSGTRSIWGDFQLFILQLMVKHPAFTDTTKRLRPPYNFSTRFLDLVRQNKSYLEPWGVIETAELKRLADIVGSSQRVRKYHPKTTFRYSAAALALQFFNLCTEKVCNSVRKIILIEDEMSVGQSNTHGRGFISLCQKNKNLHVERRVNLWKTVFTPHPFDQYDYLNGWCDREITSMQNDRLQAATVSRSIGKWMAEALALPSLGMPEGSFTLVLDGNPVPKHTSRVFRIVQRDAAWQAALDLCYSRGLVSKPSSLQRQRMNCFIFEGFPGVMQTLSTTSSLIRCNFDLGVPYDVEAIIENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4W5</accession>
    <name>W6Z4W5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_96713</name>
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    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="eggNOG" id="ENOG502QSK1">
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="546" mass="61357" checksum="0B30BABBF843EDA2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z518</accession>
    <name>W6Z518_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Blue (type 1) copper domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_91724</name>
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    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686664.1">
        <property type="nucleotide sequence ID" value="XM_007688474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z518"/>
    <dbReference type="STRING" id="930090.W6Z518"/>
    <dbReference type="GeneID" id="19127936"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91724"/>
    <dbReference type="eggNOG" id="ENOG502S40X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053381_0_2_1"/>
    <dbReference type="OrthoDB" id="1921208at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF4">
        <property type="entry name" value="CUPREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886635" description="Blue (type 1) copper domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="26055" checksum="FA62DB888590DAF4" modified="2014-04-16" version="1">MKYFTALPLAAALASAEMMVMEVAPAPAAGQKIHTVVVGGMKPVAAGMAPKLEYTPDTIKANVGDMVVFEFMQKNHTVTQSTFAEPCKKMEGGMDSGFMPNPEGMPGVTWNMTVETTEPLWFYCKQKNGVHCGKGMVFSINPAETGDKTMADFKTLAIKTNGTDLVEGGLQIVDPGAAAAPSTVGVIAGGGEAAPTGAAPPPPAPPAASPPPPAQVIAGSGMDGQGIACSCQCLCGAGSFPPTAAINSFGGYAGMIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z534</accession>
    <name>W6Z534_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_74378</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964053">
        <property type="protein sequence ID" value="EUC42674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690820.1">
        <property type="nucleotide sequence ID" value="XM_007692630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z534"/>
    <dbReference type="STRING" id="930090.W6Z534"/>
    <dbReference type="GeneID" id="19125287"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_74378"/>
    <dbReference type="eggNOG" id="KOG3437">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039415_3_1_1"/>
    <dbReference type="OrthoDB" id="24948at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08366">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016901">
        <property type="entry name" value="APC10/Doc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004939">
        <property type="entry name" value="APC_su10/DOC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12936">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12936:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03256">
        <property type="entry name" value="ANAPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028841">
        <property type="entry name" value="APC10_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01337">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51284">
        <property type="entry name" value="DOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DOC" evidence="6">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="152" mass="17400" checksum="58B6A0BEC58BEA35" modified="2014-04-16" version="1" fragment="single">LREISTLASWTVSSSKPGCSITQLRHANTNLFWQSDGPQPHYLNIHFFKLVRIVGLRLYLDFEQDESYTPTRIIFLAGSGMNDLQEWGEMRLESPRGWIWADFSGVGDVDSDGDDDDQAPKMPTLRCHLLQIKILENHQNGKDTHLRGLQVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z539</accession>
    <name>W6Z539_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_26846</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688574.1">
        <property type="nucleotide sequence ID" value="XM_007690384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z539"/>
    <dbReference type="GeneID" id="19121012"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26846"/>
    <dbReference type="eggNOG" id="ENOG502S025">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_4_1"/>
    <dbReference type="OrthoDB" id="5273647at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF123">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="33"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="373" mass="41946" checksum="D1A182E72A99BADC" modified="2014-04-16" version="1">MGHIVFANGHDQGPLLARVSLAMYTVAVTFVALRCFTRACIVKRFGLDDVFIALATVLGAAQTVTIILQVEHGQGRHTTELRIEQFNHMLMYQWINMLIYFVANWAVKMSILALYYRIGYGRKGLPWIVQAPAVWTVAGFMTAFGISSFTAQLFLCVPVSRIWDIVHVNDGGCIDVAEFMITSAAINVATDIVLLMFPLPLLRLFKFNRRQRTALVVVLSVGLIPVIASTMRLCEIVMAGRPIKPGKGWQDNDYSWGWAWVPVWSQIEVDVSILAASLPCLYPLFRHVFQSASRPATPSEMSTLPGYPESWAEQDLVSRDGSEDLEKNRKSFDFEEEKRLTVREKEMGKGIDLNISVIVDKEIDVGEDRRTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z542</accession>
    <name>W6Z542_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_37319</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688581.1">
        <property type="nucleotide sequence ID" value="XM_007690391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z542"/>
    <dbReference type="GeneID" id="19123227"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37319"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_7_1"/>
    <dbReference type="OrthoDB" id="2585655at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000318">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
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        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08910)-RELATED"/>
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    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
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        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
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    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="101"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="134"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="169"/>
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        <location>
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        </location>
    </feature>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="454"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="485"/>
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            <begin position="80"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
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            <dbReference type="EMBL" id="EUC44883.1"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5B0</accession>
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        <recommendedName>
            <fullName evidence="14">Antiviral helicase</fullName>
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        <name evidence="12" type="ORF">COCMIDRAFT_102637</name>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12 13">ATCC 44560</strain>
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        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
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    <comment type="similarity">
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        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DSHCT"/>
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    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="326"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="608"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="223"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="530"/>
            <end position="597"/>
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    </feature>
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        <location>
            <begin position="543"/>
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    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="563"/>
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        </location>
    </feature>
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        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42749.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1284" mass="143635" checksum="3BF1ADFB23522129" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5J9</accession>
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        <recommendedName>
            <fullName evidence="12">PIG-U-domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="10" type="ORF">COCMIDRAFT_35345</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGU family.</text>
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        <property type="protein sequence ID" value="EUC47042.1"/>
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        <property type="nucleotide sequence ID" value="XM_007688220.1"/>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:attachment of GPI anchor to protein"/>
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    </dbReference>
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        <property type="term" value="P:GPI anchor biosynthetic process"/>
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    </dbReference>
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        <property type="entry name" value="PIG-U"/>
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        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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            <begin position="73"/>
            <end position="95"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="133"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="173"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="216"/>
            <end position="241"/>
        </location>
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            <end position="270"/>
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            <end position="301"/>
        </location>
    </feature>
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            <end position="333"/>
        </location>
    </feature>
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            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
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            <begin position="379"/>
            <end position="404"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="46464" checksum="ABA28B9F1EFEBC80" modified="2014-04-16" version="1">MAIDSQHRLLLFGAAAAVRLLLFTLFPALPDVLAGRVEVSTPVTSFKRLQEGLFLYTHNVSPYDGGVYHQAPLLLPLFALLSHPAIAPLATYVFFTLVDLLSAHSLAQLADTGFASVTRLFASPRKDLRWSSAAIAAGFLFSPFTVATCLARSTSALTNLFVLAAMAKASQGASFTFILATAFASYLAMHPVLLFPPLMVLLYDAKALKKKSTPHLPTFVIVHTIGLAAAIGALLVGSAFLTGSWDFLAATYGVRLLLPDLTPNVGLWWYFFIEMFDSFREFFLGVFWLHAASYMPGLTIRLHKQPLFVACSLTGVFAIFTPYPSIADAALYLSLVPMFRHLFPLMRYTFLASASILYTSFLGPAFYHLWVYAGSGNANFFYAITLVWSLGLSIILGDSLYAALRDELDVQRPELQGKEVRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5U1</accession>
    <name>W6Z5U1_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_90881</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_007688151.1"/>
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    </dbReference>
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        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
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    </dbReference>
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        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887199" evidence="2">
        <location>
            <begin position="24"/>
            <end position="145"/>
        </location>
    </feature>
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        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="145" mass="16069" checksum="36B3CD729631FD21" modified="2014-04-16" version="1">MRRPPYLLFLLLTFLSSLSVSLAASPTSFCKCTCFGNSTIVALDAPSAAKKPTRHVEPRASKKTCNDCNRQFCLGYSFCTGEKEENVLTTCFQRDSAKDQAVVFIFIGATLGLLGWAGLRPWIEGWREACIQRRSYMPMAGQGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7P3</accession>
    <name>W6Z7P3_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
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    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_94009</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="KI963973">
        <property type="protein sequence ID" value="EUC46030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7P3"/>
    <dbReference type="STRING" id="930090.W6Z7P3"/>
    <dbReference type="GeneID" id="19128369"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94009"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF11">
        <property type="entry name" value="AMIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="79"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="231"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="536" mass="58697" checksum="719B2185B54F7E09" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7T6</accession>
    <name>W6Z7T6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964263">
        <property type="protein sequence ID" value="EUC39741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693741.1">
        <property type="nucleotide sequence ID" value="XM_007695551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7T6"/>
    <dbReference type="GeneID" id="19119645"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110701"/>
    <dbReference type="HOGENOM" id="CLU_2474888_0_0_1"/>
    <dbReference type="OrthoDB" id="10470757at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="88" mass="9944" checksum="AB3976E495E40330" modified="2014-04-16" version="1" fragment="single">KVQFELSTTRVIMKSIHPYILIASSHAIPRRPAIPRMVALGGMAHHVTQPRDDHCLLTWTSLGLQPSRHLSRRESFLLLVTVSPVLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7Y7</accession>
    <name>W6Z7Y7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate-binding module family 50 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_110537</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964248">
        <property type="protein sequence ID" value="EUC39801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693675.1">
        <property type="nucleotide sequence ID" value="XM_007695485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7Y7"/>
    <dbReference type="GeneID" id="19119617"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110537"/>
    <dbReference type="eggNOG" id="ENOG502S3JP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090055_0_0_1"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="147"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC39801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="192" mass="21525" checksum="F40C4F7F808D2528" modified="2014-04-16" version="1">MGQWFDMDSDAERLPSGFERIGHDADTQTYTFRDADGIMYESEPGNRYGELHRVDSPSSSQSSRSASIHLLDNRSGPSSRTFDEMFNDHQDMISKDNRETVRMMLPFALIGLVFLILVFKLLYTGDAESLTHPKGSLDCHQGSHEVQIKQADTCWAIAQTSPLTVEEMLELQCNAHVDRDQLVLGKGICVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z829</accession>
    <name>W6Z829_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">40S ribosomal protein S23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_27834</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964021">
        <property type="protein sequence ID" value="EUC43704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689758.1">
        <property type="nucleotide sequence ID" value="XM_007691568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z829"/>
    <dbReference type="STRING" id="930090.W6Z829"/>
    <dbReference type="GeneID" id="19121193"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27834"/>
    <dbReference type="eggNOG" id="KOG1749">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115574_0_1_1"/>
    <dbReference type="OrthoDB" id="1713912at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000007">
        <property type="entry name" value="40S ribosomal protein S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_uS12_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003254">
        <property type="entry name" value="PRK04211.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC43704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="15903" checksum="D1FE429933FDCF28" modified="2014-04-16" version="1">MGKGKPRGLNAARKLRNHRREGRWADLHYKKRLLGTAFKSSPFGGSSHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVGLSALWKEKKEKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z849</accession>
    <name>W6Z849_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alpha-galactosidase</fullName>
            <ecNumber evidence="11">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_25932</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase B subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="11"/>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687504.1">
        <property type="nucleotide sequence ID" value="XM_007689314.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z849"/>
    <dbReference type="GeneID" id="19120850"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25932"/>
    <dbReference type="eggNOG" id="KOG2230">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2366">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_252080_0_0_1"/>
    <dbReference type="OrthoDB" id="2866996at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004567">
        <property type="term" value="F:beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
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            <begin position="20"/>
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            <begin position="580"/>
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            <end position="1371"/>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        </source>
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        </source>
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        </source>
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        <source>
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        </source>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF17786"/>
        </source>
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            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45953.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1443" mass="162267" checksum="2FBF6F216D0343D7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z882</accession>
    <name>W6Z882_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_24171</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC47947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="116" mass="12816" checksum="62A1DE6670727AE9" modified="2014-04-16" version="1">MAPHGSNRAICCRDSHWVVARRSLRGVEGELGAHLQLARGRVGMGDCVTSFSPLHDPRPGARQRPLSREQTGLALLRTGECSAEQKSMPQVSNRWLISSSVEQFGRRQTWVVGPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8P1</accession>
    <name>W6Z8P1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_93625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EUC46158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689189.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z8P1"/>
    <dbReference type="GeneID" id="19128293"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93625"/>
    <dbReference type="eggNOG" id="ENOG502SKJA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016011_0_0_1"/>
    <dbReference type="OrthoDB" id="2399539at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="349"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963968">
        <property type="protein sequence ID" value="EUC46298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687156.1">
        <property type="nucleotide sequence ID" value="XM_007688966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z954"/>
    <dbReference type="STRING" id="930090.W6Z954"/>
    <dbReference type="GeneID" id="19120797"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25622"/>
    <dbReference type="eggNOG" id="KOG3109">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059493_0_0_1"/>
    <dbReference type="OrthoDB" id="1065058at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.450:FF:000001">
        <property type="entry name" value="SDT1p Pyrimidine nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010237">
        <property type="entry name" value="Pyr-5-nucltdase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052791">
        <property type="entry name" value="SSM1_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01993">
        <property type="entry name" value="Pyr-5-nucltdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438:SF1">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01132">
        <property type="entry name" value="C1.5.3:_5'-Nucleotidase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="30008" checksum="A5AC3EECBCFFFCC8" modified="2014-04-16" version="1">MHFNTAAPPETMKYRSKPAHDSPANGTAVVDENEKPVFFFDIDNCLYPKSLEIHRMMSELIDQFFQDHLSLSQQDANELHFRYYREYGLAIEGLVRHHKVDALEYNSKVDDALPLEDVIKPNPELRKLIEDIDTSKVRLWLFTNAYINHGKRVVKLLQIDDLFEGITYCDYGSEKFYCKPHAEMFEKAMAEAGIKSNEKCYFVDDSYINCKAAEERGWKTAHLLDEKDPAPEVPASKYQIRSLQELRKIFPEVFKSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9P8</accession>
    <name>W6Z9P8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_98734</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689243.1">
        <property type="nucleotide sequence ID" value="XM_007691053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9P8"/>
    <dbReference type="STRING" id="930090.W6Z9P8"/>
    <dbReference type="GeneID" id="19129321"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98734"/>
    <dbReference type="eggNOG" id="KOG1967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005943_1_0_1"/>
    <dbReference type="OrthoDB" id="342900at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024687">
        <property type="entry name" value="MMS19_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029240">
        <property type="entry name" value="MMS19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12460">
        <property type="entry name" value="MMS19_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14500">
        <property type="entry name" value="MMS19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="MMS19 N-terminal" evidence="7">
        <location>
            <begin position="40"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="MMS19 C-terminal" evidence="6">
        <location>
            <begin position="550"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1024" mass="112747" checksum="70AA69F277571E82" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9Q8</accession>
    <name>W6Z9Q8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">xanthine dehydrogenase</fullName>
            <ecNumber evidence="3">1.17.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">COCMIDRAFT_6414</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>hypoxanthine + NAD(+) + H2O = xanthine + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24670"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>xanthine + NAD(+) + H2O = urate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="18">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="18">Binds 2 [2Fe-2S] clusters.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.4" evidence="3"/>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689217.1">
        <property type="nucleotide sequence ID" value="XM_007691027.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z9Q8"/>
    <dbReference type="GeneID" id="19124953"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6414"/>
    <dbReference type="eggNOG" id="KOG0430">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001681_1_2_1"/>
    <dbReference type="OrthoDB" id="8300278at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004854">
        <property type="term" value="F:xanthine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000015">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000003">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.50:FF:000001">
        <property type="entry name" value="Aldehyde oxidase 1"/>
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        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
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        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
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        <property type="entry name" value="2Fe-2S-bd"/>
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        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
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        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
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        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
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        <location>
            <begin position="35"/>
            <end position="124"/>
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            <begin position="318"/>
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            <position position="1420"/>
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    </feature>
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        <location>
            <position position="74"/>
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            <name>[2Fe-2S] cluster</name>
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        <location>
            <position position="79"/>
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        <location>
            <position position="82"/>
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            <name>[2Fe-2S] cluster</name>
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            <name>[2Fe-2S] cluster</name>
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        <location>
            <position position="145"/>
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            <name>[2Fe-2S] cluster</name>
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            <name>[2Fe-2S] cluster</name>
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        <location>
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            <name>FAD</name>
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        <location>
            <position position="484"/>
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        <location>
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        <location>
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            <name>FAD</name>
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        <location>
            <position position="571"/>
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        <location>
            <position position="910"/>
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            <name>Mo-molybdopterin</name>
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            <name>Mo</name>
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            <name>substrate</name>
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            <position position="1055"/>
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            <name>Mo-molybdopterin</name>
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            <name>Mo</name>
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            <dbReference type="EMBL" id="EUC44249.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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    <sequence length="1496" mass="164148" checksum="16F69072CC0EB076" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAK2</accession>
    <name>W6ZAK2_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_33840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
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        <property type="nucleotide sequence ID" value="XM_007686537.1"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030671_1_0_1"/>
    <dbReference type="OrthoDB" id="5396at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF10">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="36180" checksum="F55AD0EFAA5BC280" modified="2014-04-16" version="1">MAPVNNTLCPLFLANSFLNSTLPSVPEFDILPSCAGLPQGCACGVSDDSKAKDIYGTLNLLTEDVILSAKQEITEGVSISLRSNLDGFKSSNTNRKHLNNTFVSLKDDGLGSFGWDKEISFNTQISSHWDSFCHYPHQGTGIAYNSASCTREQLEGTTTNSTKPPTLDQWQLRGGVVGRGVLLDYAKYVESEGIQVSPFTYHSITAQILEEVADFQGTELRAGDILVVRTGYVGALPKLNETEQRNATRSAGSIGLEPSCDMARWIWNHQFAAVAGDSPAVEAFNANLSSEYWELDKLSAHCHKSGKYSFFLTSIPFNVPNMIAGPPNALAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAS2</accession>
    <name>W6ZAS2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_91205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686432.1">
        <property type="nucleotide sequence ID" value="XM_007688242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAS2"/>
    <dbReference type="GeneID" id="19127832"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91205"/>
    <dbReference type="HOGENOM" id="CLU_2903868_0_0_1"/>
    <dbReference type="OrthoDB" id="10311146at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="62" mass="6716" checksum="538B7CCD25A7795B" modified="2014-04-16" version="1">MRGAEPIGGANSWDRLQVITRLRRARLKPLQASSLCSKHESLSSVPNGIRTPTNAALPHLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB21</accession>
    <name>W6ZB21_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_107561</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964131">
        <property type="protein sequence ID" value="EUC40921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692566.1">
        <property type="nucleotide sequence ID" value="XM_007694376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB21"/>
    <dbReference type="GeneID" id="19119072"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107561"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF6">
        <property type="entry name" value="CYTOCHROME P450 2C30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC40921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="62470" checksum="72E187E55F3D9122" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBV9</accession>
    <name>W6ZBV9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_96911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688547.1">
        <property type="nucleotide sequence ID" value="XM_007690357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBV9"/>
    <dbReference type="GeneID" id="19128942"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96911"/>
    <dbReference type="HOGENOM" id="CLU_200649_0_0_1"/>
    <dbReference type="OrthoDB" id="3683549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="73" mass="8463" checksum="56CE0DAA0AAE543C" modified="2014-04-16" version="1">MTTGKRLDRRTIVTVCLVAALWHPAFWRILPVGACLQWNRRRSLQWGEVLLYIKLKRPDAFSTPMVPTVPAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCA8</accession>
    <name>W6ZCA8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_24472</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685830.1">
        <property type="nucleotide sequence ID" value="XM_007687640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCA8"/>
    <dbReference type="STRING" id="930090.W6ZCA8"/>
    <dbReference type="GeneID" id="19120596"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24472"/>
    <dbReference type="eggNOG" id="KOG4210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026791_2_0_1"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="239"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="339"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="415"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="319"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="422"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="493" mass="51481" checksum="7D7D23EADFDBA887" modified="2014-04-16" version="1">MGKTKVADKSSKKDKKAELSSIKAGRVTKPAATPKSKSKDIAKSVASNVKDKKSKKALTPEPESDSSSESESESEESEESSSEEEEVTKKTAAKAKAAPKAAAKADSDSDSSDSSEEDSDSESESSEEEKPAPKAKANGVKTNGAAKAKAESSDSESDSESESDSDSSESKDEKPAAKAEAASTSDSDDSSDSDADSDSSESESDEAEAPSKKRKAEEVAEPVIKKTKTDEPVAEDGVKNLFVGNLSWNIDEDWLRREFESFGEIVGCRVITDRETGRAKGFGYVEFAKAADAAKAQKDMHEYELDGRPLNVDFSTPRQKPDTNARANKFGDKRSAPSNTLFIGNLSFDCTNETIQEVFAEYGNVTRVSLPTDRDSGALKGFGYVDFGSQEEATAALEALQGQDVAGRPLRVDFAAPRDDNGGGGGRGGFGGGRGGGRGGRGGFGDRGGRGGGRGGGGFGGRGGRGGGRGGGRGGSFNRGGFGDFQGQKKSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCK0</accession>
    <name>W6ZCK0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_33175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683989.1">
        <property type="nucleotide sequence ID" value="XM_007685799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCK0"/>
    <dbReference type="GeneID" id="19122261"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33175"/>
    <dbReference type="eggNOG" id="ENOG502SI8G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_1_1"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF57">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="32"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC49542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="374" mass="40941" checksum="69E8036514FD06D4" modified="2014-04-16" version="1">MHRTIPIENGQQVGVVIASSISISIAVVAVGLRLMAKRIRNRVDGSDWCIVVACLWNAALHGTCISLVTHGGFGFHITEIMRRFGPGTATYFFKGIMTFSMLWNATVCFSKLSILLMYTALIPTPTMIRMSVTFGAFIVVWCIANIMTAFLICRPLARNWDFTVPGTCGSQPDFYFTMGIINLITDALLIGMPMPYLYKLAMPMRKKLLAMGLLSIGIGTWAITIYRQTLLPDLNFADMTHDGVLATLLSGLEPAVAIVLSCVPLLRPLFGKSRHNLDSGYQYGSSSGKQISFMSKRGAGASRGLDPTATFSELVDQTNNSSQIELRPVEGIQRVCISSDEERGKDGRGNILGAKGGVPPRTISVERMWEVRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCP8</accession>
    <name>W6ZCP8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cysteine proteinase 1, mitochondrial</fullName>
            <ecNumber evidence="8">3.4.22.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_105949</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.</text>
    </comment>
    <comment type="function">
        <text evidence="6">The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.</text>
            <dbReference type="EC" id="3.4.22.40"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase C1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.40" evidence="8"/>
    <dbReference type="EMBL" id="KI964099">
        <property type="protein sequence ID" value="EUC41511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691974.1">
        <property type="nucleotide sequence ID" value="XM_007693784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCP8"/>
    <dbReference type="STRING" id="930090.W6ZCP8"/>
    <dbReference type="MEROPS" id="C01.085"/>
    <dbReference type="GeneID" id="19118774"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105949"/>
    <dbReference type="eggNOG" id="KOG4128">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038600_0_1_1"/>
    <dbReference type="OrthoDB" id="2666448at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </evidence>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDU7</accession>
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        <submittedName>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
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        <source>
            <dbReference type="EMBL" id="EUC41676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="74" mass="8084" checksum="0DA5A7AC4094427E" modified="2014-04-16" version="1">MDLTVDIRPDVKCGYVSASRNAEPECHGRCTKAIPIHPIFQDLDTDAEKVHGRPAYTLVSILIIVRQVSPGATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE70</accession>
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            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="9" type="ORF">COCMIDRAFT_36483</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
                <person name="Barry K."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </dbReference>
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    <dbReference type="OrthoDB" id="2441642at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="502"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="86"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="554"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="585" mass="63756" checksum="F84DF5B5498E0A1A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF35</accession>
    <name>W6ZF35_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_23597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684816.1">
        <property type="nucleotide sequence ID" value="XM_007686626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF35"/>
    <dbReference type="GeneID" id="19120467"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23597"/>
    <dbReference type="eggNOG" id="ENOG502RIRQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_769742_0_0_1"/>
    <dbReference type="OrthoDB" id="3798352at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="374" mass="41014" checksum="8F42B83B38D2ED07" modified="2014-04-16" version="1">MSQSQRNGPETDTIDLTLSSPEPEFWSPSPTREQIRAPPQQSHLSFGPTYNTSRVKQESGHVPRIKSDPGQPSHIQTTSAQPSRGMMSFGQSATSSRNLVAPQQARPINPSHIQSIISTVSPYVLQTVLVELCQISPAFSGALVRGLAPHSTSARNMINQHRMEIDRNFAYEAMNTTSSSGRYTSQGNQRSYIRQHPYGSHTIPRIKREPHRPTTPSSDSELRRPGPSSQKVALPAATRLPLHHLTGGSPSSNITSNAATVTQRTDEVQKTTPNVTKTCTKCHESFSGDEEPCIYHPGRKIKQEDGTIIWSCCQEDMLSVGCDFGGTHITQYHEPKDMPTEQESLSGSSASHNNYEKPFKILGRPSTGSRGGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF57</accession>
    <name>W6ZF57_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_86945</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684965.1">
        <property type="nucleotide sequence ID" value="XM_007686775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF57"/>
    <dbReference type="STRING" id="930090.W6ZF57"/>
    <dbReference type="GeneID" id="19126958"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86945"/>
    <dbReference type="eggNOG" id="ENOG502QS4Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031603_4_1_1"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046355">
        <property type="term" value="P:mannan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000076">
        <property type="entry name" value="Mannan endo-1,4-beta-mannosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012339140" description="mannan endo-1,4-beta-mannosidase" evidence="9">
        <location>
            <begin position="16"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="10">
        <location>
            <begin position="157"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="375" mass="41658" checksum="BCF0A350B8A42732" modified="2014-04-16" version="1">MKLLPLLFLSATAAALPTSFDVSARASVSKVDGLKFNIDGTTKYYAGTNSYWMPFLTNDTDVDIIMSHLAASGTKILRVWGFNDVDGEPDPSSVYFQSFSGSTATINTGTNGLQRLDTVVASASTYGIKLIIPFVNNWEDYGGMHAYFRACGVLIHAQWYTKAECQAMYQAYIAAVISRYRDSPAIFAWELANEPRCRLCPTSILTNWIRQTSNYVRSLDSEHMITVGDEGFGLEGGAWFQYPYWYIEGIDWAANLALPNISFGTFHLYPEHWLVGGSFGDEWIRLHVEVCARIGKPCLLEEYGVSKREEQCAVEGAWQKTSLGLGESGMAADLFWQLGDTVVSTGEATHDDGFTVYYESEQWNCLVGEHLEAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFD6</accession>
    <name>W6ZFD6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682798.1">
        <property type="nucleotide sequence ID" value="XM_007684608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFD6"/>
    <dbReference type="GeneID" id="19125216"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_721"/>
    <dbReference type="eggNOG" id="ENOG502SQAA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_4_4_1"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43857">
        <property type="entry name" value="BLR7761 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43857:SF1">
        <property type="entry name" value="YJGH FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="149" mass="16013" checksum="4F711A3F73673648" modified="2014-04-16" version="1">MASNKPNAFNPPSVVEPPPTYSQVCVTPIVATSALVTLAGQTGLQKDGTVPSGIKAQAKAAYESIHKCLEAAGATPRDIVFVRHYIVKETGDKEQDAKDVVERGWGEEWMEFMDKNADGHRPPDTVVGVASLALGKLLYECEVTAMISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFP3</accession>
    <name>W6ZFP3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_23474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFP3"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_23474"/>
    <dbReference type="eggNOG" id="ENOG502SV1N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059948_0_0_1"/>
    <dbReference type="OrthoDB" id="5120991at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="372" mass="42834" checksum="62CB11CD2DC8D889" modified="2014-04-16" version="1">MGRPVFTSRDNLALLRSSAFESEHAWLYDTSYMQHGAAALELEHEIEQAYSSISPDDLSDEQVRIIKTQITIHRERQRALRPHLESGSDQIDEEGNECVFVPAPNQWGANGDLDEESETLSAIHNLLTWQTSYSPISHALYDELPSTDIPYHALLDPSLPTTTFHLHRTREWTGSSGFRKYIYSARDHSDRYMLYMLEATHRDDSQVNAADFFRVAEFPQPCISVLLSGIDKKRMTTDSSKDAAYKSRCIHLRGPFSQPVKEYPDRQQKIPWSPRRFTYGGRRFVWKQGDPNDDAMPETLYEYQKDWAKPGSRTGKRCDDAKPIKLVWGEKRRKGKVDSYTIHFRGGMDQVFREILLASQMARQVCLFTAMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFP8</accession>
    <name>W6ZFP8_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_29028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964065">
        <property type="protein sequence ID" value="EUC42321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691150.1">
        <property type="nucleotide sequence ID" value="XM_007692960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFP8"/>
    <dbReference type="GeneID" id="19121424"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29028"/>
    <dbReference type="HOGENOM" id="CLU_2183477_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="109" mass="12085" checksum="C64C99F12FDD9F63" modified="2014-04-16" version="1">MPPRFPRFPAPFMRQINFTRLLKTILGEAAACTEEQRMPPVTGSRSGATGLETSRARSSVWCVRAREGRGKVGWLGVAVARVKLRAGEMRFASCGVVHLQRLEGSYVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFS1</accession>
    <name>W6ZFS1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">O-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_23450</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Sterol O-acyltransferase that catalyzes the formation of stery esters.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684613.1">
        <property type="nucleotide sequence ID" value="XM_007686423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFS1"/>
    <dbReference type="STRING" id="930090.W6ZFS1"/>
    <dbReference type="GeneID" id="19120435"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23450"/>
    <dbReference type="eggNOG" id="KOG0380">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018190_2_0_1"/>
    <dbReference type="OrthoDB" id="10039049at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034737">
        <property type="term" value="F:ergosterol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008204">
        <property type="term" value="P:ergosterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF9">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000439">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="402"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="501"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="530"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000439-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC48885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="553" mass="63734" checksum="2ECDEC984B3EF0FA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG00</accession>
    <name>W6ZG00_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_2218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684485.1">
        <property type="nucleotide sequence ID" value="XM_007686295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG00"/>
    <dbReference type="STRING" id="930090.W6ZG00"/>
    <dbReference type="GeneID" id="19120201"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2218"/>
    <dbReference type="eggNOG" id="ENOG502R6ZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021857_0_0_1"/>
    <dbReference type="OrthoDB" id="3796651at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="582" mass="63695" checksum="9E5504163CF4F366" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG33</accession>
    <name>W6ZG33_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA 4-demethylwyosine synthase (AdoMet-dependent)</fullName>
            <ecNumber evidence="4">4.1.3.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_81183</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:36347"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10165"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="EC" id="4.1.3.44"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TYW1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.44" evidence="4"/>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682749.1">
        <property type="nucleotide sequence ID" value="XM_007684559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG33"/>
    <dbReference type="STRING" id="930090.W6ZG33"/>
    <dbReference type="GeneID" id="19125817"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81183"/>
    <dbReference type="eggNOG" id="KOG1160">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007952_1_2_1"/>
    <dbReference type="OrthoDB" id="271553at2759"/>
    <dbReference type="UniPathway" id="UPA00375"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102521">
        <property type="term" value="F:tRNA-4-demethylwyosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013917">
        <property type="entry name" value="tRNA_wybutosine-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034556">
        <property type="entry name" value="tRNA_wybutosine-synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08608">
        <property type="entry name" value="Wyosine_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00284">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01071">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="14">
        <location>
            <begin position="134"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="432"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="310"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="770"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="773"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC50772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="794" mass="88999" checksum="F219926D87C6275C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG52</accession>
    <name>W6ZG52_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_44880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684636.1">
        <property type="nucleotide sequence ID" value="XM_007686446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG52"/>
    <dbReference type="STRING" id="930090.W6ZG52"/>
    <dbReference type="GeneID" id="19124257"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_44880"/>
    <dbReference type="eggNOG" id="KOG0987">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_703133_0_0_1"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="3">
        <location>
            <begin position="302"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="91"/>
        </location>
    </feature>
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        <location>
            <begin position="128"/>
            <end position="256"/>
        </location>
    </feature>
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            <begin position="13"/>
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        </location>
    </feature>
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            <end position="66"/>
        </location>
    </feature>
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        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
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            <begin position="141"/>
            <end position="169"/>
        </location>
    </feature>
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        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="188"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="393" mass="42620" checksum="358A7D1098F48BA8" modified="2014-04-16" version="1" fragment="single">MFKQAVQAHDAIASSSPSNGACKQASLGNAFSRTGSTQTPSARTLGYGAKQNSIVGQQRVSGPTTQGTKRTSSGLSKSLSSHDGEFEYPTLSIGDMDKENDLPAAFQAPSTGSGILETALFDEDDFDSDVDLDVEDPATKGTVTYPTLPSAPSTISGDSGYNSRTQTADTKSEVDSSQPIPWSSSPIEHFKTPKKSEPLRVKRRTLPWPQPQKTQPLQEEEEEDEVEPPKKKQSVEPEKPASTPAPKDSKYYWNTTPNGLKQQQKAFRENMKAQARPTQGIDDGVKEVIKTKKKNTVARIFLSEEQQNVLKLVVDYKKSVFFTGSAGTGKSVLLREIITGLRKKYAREPDRVAVTASTGLAACNIGGVTLHSFAGIGLGKEPVEDLVKKIRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGI7</accession>
    <name>W6ZGI7_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_33656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502SMUJ">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="180"/>
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        </location>
    </feature>
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        <location>
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            <end position="241"/>
        </location>
    </feature>
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    </feature>
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        <location>
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            <end position="314"/>
        </location>
    </feature>
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        <location>
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            <end position="416"/>
        </location>
    </feature>
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        <location>
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            <end position="578"/>
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        <location>
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        </location>
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        <location>
            <begin position="662"/>
            <end position="692"/>
        </location>
    </feature>
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        <location>
            <begin position="614"/>
            <end position="623"/>
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    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="692" mass="76045" checksum="C6626E741ED147F3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGR6</accession>
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        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_21451</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684131.1"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="10624716at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC51052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="157" mass="17434" checksum="637B5B0669F4208C" modified="2014-04-16" version="1">MADFACLDLLAGYGPWAMGHGLCRMWARRDRQRAVSREKANMARSQGRVVEVLGAVNRSASANHRVWACCGCYCYYCTQVATHQPTSPPTRQPAAGQVWMREGWEGRGPWHGNTLVGKAEDRDEWVPQAVCARQLIRASWNHPPGGLGGRVQGARMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI97</accession>
    <name>W6ZI97_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_1539</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
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        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M67C family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC49705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI97"/>
    <dbReference type="STRING" id="930090.W6ZI97"/>
    <dbReference type="MEROPS" id="M67.A14"/>
    <dbReference type="GeneID" id="19119888"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1539"/>
    <dbReference type="eggNOG" id="KOG2880">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023304_4_0_1"/>
    <dbReference type="OrthoDB" id="3640at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061578">
        <property type="term" value="F:K63-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070530">
        <property type="term" value="F:K63-linked polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120113">
        <property type="term" value="P:cytoplasm to vacuole targeting by the NVT pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070536">
        <property type="term" value="P:protein K63-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd08066">
        <property type="entry name" value="MPN_AMSH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000033">
        <property type="entry name" value="AMSH-like protease sst2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.80:FF:000024">
        <property type="entry name" value="Endosome-associated ubiquitin isopeptidase (AmsH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044098">
        <property type="entry name" value="STAMBP/STALP-like_MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015063">
        <property type="entry name" value="USP8_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12947">
        <property type="entry name" value="AMSH-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12947:SF13">
        <property type="entry name" value="FI19924P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08969">
        <property type="entry name" value="USP8_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140856">
        <property type="entry name" value="USP8 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="10">
        <location>
            <begin position="361"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="110"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="262"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="539" mass="60571" checksum="CCA4CE8A2FCE8D4D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIA3</accession>
    <name>W6ZIA3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Required for respiratory growth protein 9, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_38832</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for respiratory activity and maintenance and expression of the mitochondrial genome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRG9 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690269.1">
        <property type="nucleotide sequence ID" value="XM_007692079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIA3"/>
    <dbReference type="GeneID" id="19123561"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38832"/>
    <dbReference type="eggNOG" id="ENOG502S7IA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047598_1_0_1"/>
    <dbReference type="OrthoDB" id="5578174at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010487">
        <property type="entry name" value="NGRN/Rrg9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13475">
        <property type="entry name" value="NEUGRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13475:SF3">
        <property type="entry name" value="NEUGRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06413">
        <property type="entry name" value="Neugrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="215"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC43231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="251" mass="28906" checksum="D0DFE6B9D999A1D5" modified="2014-04-16" version="1">MSCHNCTRRTLSLFIQSFANAKPVFPTGRPLIYPQPSRFRSDSRRLQRIDRPSSGKTKAQSDVDAEVEDALTGEIQAKNERPAWQVQKEALKEKLGGEAWNPRKKLSPDTMEGIRHLNSTQPDKFTTPVLANHFKVSPEAIRRILKSKWRPSDEEYEERMERWNKRGERIWSNLVEMGVKPPKRWRDMGVGRAQNGELPRWKSRYRNQVYVQDSFGGDRASYEPDEDILPTVGKSGKSKPTTSSVPLSQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJK6</accession>
    <name>W6ZJK6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">General transcription and DNA repair factor IIH subunit TFB4</fullName>
            <shortName evidence="14">TFIIH subunit TFB4</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">RNA polymerase II transcription factor B subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_32502</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the TFB4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683288.1">
        <property type="nucleotide sequence ID" value="XM_007685098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJK6"/>
    <dbReference type="STRING" id="930090.W6ZJK6"/>
    <dbReference type="GeneID" id="19122123"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32502"/>
    <dbReference type="eggNOG" id="KOG2487">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040211_0_0_1"/>
    <dbReference type="OrthoDB" id="17307at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000084">
        <property type="entry name" value="Transcription factor TFIIH subunit Tfb4, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004600">
        <property type="entry name" value="TFIIH_Tfb4/GTF2H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03850">
        <property type="entry name" value="Tfb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="344"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC50168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="377" mass="39858" checksum="A070621B368F253E" modified="2014-04-16" version="1">MNTIDGSDRHIKTEEAPPPSLLAIVLDTNPHAWAHLSSTLSLSTALANILVFINAHLASGNTNEVAVIASHSHKTTFLYPSPVAPQTQPRNGTANGDVEMNGTGDDKGQHAAESANKYRPFAVVESTILQNFVKLLNETKESHLEATPTTLIGGALSMALTHINKQTILHAPTAASAESASLAALADSENTHVDRVSLTSRILIVSVSGDLANQYIPVMNSIFAAQRKRIPIDILKLAGDTVLLQQASDATGGVYMKPERPEGLLQYLMMAFLPDVTARASLVVPSAGGVDFRAACFCHRKVVDIGFVCSVCLSIFCSPDLPGNLCLTCGSYLSLRSAMTNPPALIPRKKKKKKKAGIDSATPGTNTPVGSGTPAHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJQ8</accession>
    <name>W6ZJQ8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_99763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689650.1">
        <property type="nucleotide sequence ID" value="XM_007691460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJQ8"/>
    <dbReference type="GeneID" id="19129529"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99763"/>
    <dbReference type="HOGENOM" id="CLU_2557945_0_0_1"/>
    <dbReference type="OrthoDB" id="10395242at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="82" mass="9016" checksum="6B04FBC9D507CB2C" modified="2014-04-16" version="1">MDPLDRCHALLACLRHALGIGSCALQTPLYLFQHVCFALLSTNRHAAATCQRALSPLQPCCGLWVVNRARCSLYCYIPSLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKH3</accession>
    <name>W6ZKH3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="3 8">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_32303</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683034.1">
        <property type="nucleotide sequence ID" value="XM_007684844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKH3"/>
    <dbReference type="STRING" id="930090.W6ZKH3"/>
    <dbReference type="GeneID" id="19122068"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32303"/>
    <dbReference type="eggNOG" id="KOG1175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_6_1"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05966">
        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000004">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000001">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001208">
        <property type="entry name" value="PRK00174.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="11">
        <location>
            <begin position="45"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="9">
        <location>
            <begin position="103"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="10">
        <location>
            <begin position="550"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC50483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="670" mass="74608" checksum="29F9CF6BF47DFE0D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLN0</accession>
    <name>W6ZLN0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_2686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685003.1">
        <property type="nucleotide sequence ID" value="XM_007686813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLN0"/>
    <dbReference type="STRING" id="930090.W6ZLN0"/>
    <dbReference type="GeneID" id="19121014"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2686"/>
    <dbReference type="eggNOG" id="ENOG502SEGI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033247_0_0_1"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021838">
        <property type="entry name" value="DUF3431"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37490">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37490:SF1">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11913">
        <property type="entry name" value="DUF3431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="390" mass="45105" checksum="984351416AC6764C" modified="2014-04-16" version="1">MTAVIGCFTTLSLRRSYSSWYQLCFYFLAVLCICGHEVYRSSWKQARQPKDPHGSYDMVPCSPRTRSDDSEEAGEADILASRPDYTHGFRSSFSSIVLVMLWTAYISFNFGQRQYPRIEPRLDLKYEANSPLEVVISMYKERTQDVASLISKLHTMPQMSQALVTIYLKDGQADEEKVKQETKAHNVVKLPNVGREAETYLNHIVNRWDKLAERTIFLQADIHNPREFYPFFQRYFRANQTGFLNLGWTGNVCYSDDCGDKQGWQDETSLFPEIQSRIDHSVRDGILLSYKGQFVATAARIRGIDKAIYDDLWRLLVDEKSWAHSEPYLQDREDGMSKPWFGYTMERIWNVLFQCSDMDVAWKCPTLLSGWRSGGGIADCQCFDTELVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLR6</accession>
    <name>W6ZLR6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_2721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685008.1">
        <property type="nucleotide sequence ID" value="XM_007686818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLR6"/>
    <dbReference type="GeneID" id="19121080"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2721"/>
    <dbReference type="eggNOG" id="KOG4169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_13_0_1"/>
    <dbReference type="OrthoDB" id="5371740at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05323">
        <property type="entry name" value="ADH_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="31511" checksum="ECF5B331D4A4BC46" modified="2014-04-16" version="1">MSKPVAIVTGAGSGIGEATATHLHSLGYKVVIADLNPTSGQRVASALGADALFHQTDVSSYKSQAQLFKRAYEWGGNRLDFCHANAGIDDRQNVYEGMDKEEVDEEGLVKKLNTKTMDVNLEAVIQGLWLFKYYVRRSKEAGGGKGYFVATSSAVGLYFMPQCPQYTASKYGVVGFVRASAPNFINENITVNAICPAFIPTNLCPPEVAARWPKEHVTPLSTVLKAIDAFLKDDKLTGQAVELSQENIYFRQPVDFVNESQRWIGLESHKFWNEGYKEPPKRNGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLZ5</accession>
    <name>W6ZLZ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_535</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682502.1">
        <property type="nucleotide sequence ID" value="XM_007684312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLZ5"/>
    <dbReference type="GeneID" id="19124587"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_535"/>
    <dbReference type="eggNOG" id="ENOG502QUV4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_4_2_1"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889938" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="18"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="156"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="622" mass="68368" checksum="1F341330F01CBE8A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLZ6</accession>
    <name>W6ZLZ6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_34048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684945.1">
        <property type="nucleotide sequence ID" value="XM_007686755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLZ6"/>
    <dbReference type="GeneID" id="19122474"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34048"/>
    <dbReference type="HOGENOM" id="CLU_1030530_0_0_1"/>
    <dbReference type="OrthoDB" id="3694289at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="264" mass="29632" checksum="36522E42E43DA793" modified="2014-04-16" version="1">MIPTSLSFTAVNDASCPNFFGSQEHRTQVSRAITESLFGTTTTYESLTLKATIRHQTPPDRWEKPARDILSDIPADVMTERNNPFLQRSGCTLLPAAQLQRTRTPQPESHTPRDNINTTQPLVSPLSPPPSHSHPPRPLPSSQFECGQRTVWTPPPPTLPRCSLSPKQEAHQKYPFGPPITPGMPATRESVHGDLARNPAVEHVQGGKMEDIISVIDKEIALCEIREKYEEAVQRALLARYNGLVWRWRRERVVRGEKQKGGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMC8</accession>
    <name>W6ZMC8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_31385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
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    </dbReference>
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            <end position="238"/>
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        <location>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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    </protein>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">ATCC 44560</strain>
        </source>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
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            <end position="20"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC51198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="727" mass="80589" checksum="D49D55F5A04B2C12" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMM1</accession>
    <name>W6ZMM1_COCMI</name>
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        <submittedName>
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        </submittedName>
    </protein>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686587.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="617" mass="69624" checksum="8267DAA2C144610D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMR3</accession>
    <name>W6ZMR3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_79279</name>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
            <begin position="540"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="584"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="605" mass="68175" checksum="42EFF40F4B679C0B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNZ8</accession>
    <name>W6ZNZ8_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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            <taxon>Bipolaris</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
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        <location>
            <position position="112"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="112" mass="13134" checksum="702BA362B4847751" modified="2014-04-16" version="1" fragment="single">MEGNGYGNGWWRSGIRSVFVYYPSSAFFVLLLYNKTLVYGFLWEDWTRESVSKAKKVYRMHAMKYYCLTGASVIAYILTTRIHEDGQSVSKVSLRMFNWRHTTLSRLKTTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPC2</accession>
    <name>W6ZPC2_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="8" type="ORF">COCMIDRAFT_84722</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC49349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685909.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZPC2"/>
    <dbReference type="GeneID" id="19126518"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84722"/>
    <dbReference type="eggNOG" id="KOG0024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_3_1"/>
    <dbReference type="OrthoDB" id="442947at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08284">
        <property type="entry name" value="FDH_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF2">
        <property type="entry name" value="DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="7">
        <location>
            <begin position="25"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="197"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="38422" checksum="F16EC7D44B683F88" modified="2014-04-16" version="1">MKAVVFKGPGKVVIEERPIPKIRDDKDIIVKVDKTALCGSELHVFRGHQPSGTEFVMGHEFTGYVHEVGASVKNHKVGDQVVTPFTTSCGECFYCSHGYSSRCTKSQLFGSVGLDGAQAEYVRVPLADSTAVKAPPGIKDEVLVLMADIFPTGMFAAKNGFQYSSPEEIKDSVVVLIGCGPVALCALCNITDYKPKHILAVDSVPSRLELARSLGAEPWNFQTDREGLNKRVKELTEGRGADIVIEVVGLSPALRMGYELIRPWGVISSVGVHNGEIPWTGNEAYNKNVRVQMGRCPVRSVFEEAMESLKRHQDKLGFMADKIMPLSEAVEGYDLFDKMKVQKVVFEAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQM9</accession>
    <name>W6ZQM9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_1429</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
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                <person name="Barry K."/>
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        <location>
            <begin position="357"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="871"/>
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            <begin position="24"/>
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        <location>
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        <location>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="nucleotide sequence ID" value="XM_007684549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTA5"/>
    <dbReference type="GeneID" id="19125811"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81141"/>
    <dbReference type="HOGENOM" id="CLU_663904_0_0_1"/>
    <dbReference type="OrthoDB" id="3695169at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="259"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="411" mass="46717" checksum="614347EDB23D46FE" modified="2014-04-16" version="1">MSVASPNNKKPRKKYVLGDFVKYATGIFAAHFVAISDMGLYEFAEKQYIDENQQCNTCHMIMVGHYHRKSSGLPVWAESTGEEIWYYKWTGCRVEPLSRGIQSGKVYYDPPFSYIGGIISDRDTGRGMTQERKFQRAVVESVIHFIFLATGRLNQTSDITNPDLLGHFKLALKNLLQNREAHEATNRTPTQRLPTHVEETPIANNEALPSKVSETRHKNSISDIIQRPLPPIFTASLDRRVIDLTRDVSGSSSQAPNECVLLEQQVRDLKAKLEEQEAMTNALEARLVREKARRQRLRNQRERWTIKRQALKAKISAKGQRLAEWKATAREHQLQIAAVTEELAREKEELRCEKKARMFWQHKHNSLPRMLLERSRLAATSGSPNGQESSVAMVKTQGVGGSFGSAHSRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTJ7</accession>
    <name>W6ZTJ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific]</fullName>
            <ecNumber evidence="5">2.5.1.87</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_80717</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate</text>
            <dbReference type="Rhea" id="RHEA:53008"/>
            <dbReference type="Rhea" id="RHEA-COMP:19494"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:136960"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.87"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.87" evidence="5"/>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682571.1">
        <property type="nucleotide sequence ID" value="XM_007684381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTJ7"/>
    <dbReference type="STRING" id="930090.W6ZTJ7"/>
    <dbReference type="GeneID" id="19125715"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80717"/>
    <dbReference type="eggNOG" id="KOG2818">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051870_1_0_1"/>
    <dbReference type="OrthoDB" id="19639at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038887">
        <property type="entry name" value="Nus1/NgBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21528">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21528:SF0">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC50869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="348" mass="39733" checksum="6047F4FC50E1303F" modified="2014-04-16" version="1">MAAVTGLSSKQESAFRRKELSAQEREELLKPFLPTDISDSDTQAQKKKALRERRQRASQQHHRKPLVGPVKALLHLTIYHIVALLFSIFFRFRRAYRLVRGKVISLLKYHHRTPEFIAHDVKNLEKLPKHLSVIVEYQEDDGSQGNAGLEGLVNDVCEIAAWAASAGIPFLSIYERTGVLKNYLPQTHASIWSTLEAYFGPKRKPTLSLRAPHLSSYSPPDTPPQLAEPNDPNLKEERQHLTVLLLSEHDGRDTIVDLTRTLAEMAQKGDVRQEQINMDLIDAQLNDHVSSEPDLLILFSPTVQLKGYPPWQLRLTEIFHLPDNKGVNYQVFLRALYNFAKVEMRLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTL5</accession>
    <name>W6ZTL5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcriptional regulatory protein DEP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_21606</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682509.1">
        <property type="nucleotide sequence ID" value="XM_007684319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTL5"/>
    <dbReference type="STRING" id="930090.W6ZTL5"/>
    <dbReference type="GeneID" id="19120086"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21606"/>
    <dbReference type="eggNOG" id="ENOG502S14R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_342938_0_0_1"/>
    <dbReference type="OrthoDB" id="20886at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21964">
        <property type="entry name" value="BREAST CANCER METASTASIS-SUPPRESSOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08598">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="236"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="501"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="553"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="589"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="647"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="650"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="688" mass="75244" checksum="9DC811666D9C3CA9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTS8</accession>
    <name>W6ZTS8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_3845</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686293.1">
        <property type="nucleotide sequence ID" value="XM_007688103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTS8"/>
    <dbReference type="STRING" id="930090.W6ZTS8"/>
    <dbReference type="GeneID" id="19123469"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3845"/>
    <dbReference type="eggNOG" id="KOG0743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010189_6_2_1"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19510">
        <property type="entry name" value="RecA-like_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000768">
        <property type="entry name" value="Probable mitochondrial chaperone bcs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="14">
        <location>
            <begin position="42"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="264"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC47131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="54313" checksum="63C175DAF8F3B7DE" modified="2014-04-16" version="1">MEPNTPQHQLARQMTAARGDSSASLFSQAADNPFFTAGFGLAALGVAARTGQKGLQHGAAFIKRRMLVDLEITRHDDAYPWVLQWMTNYHRAQQAGARPLAHNTVLAKILNRIDPRMHHLQVQTYTPPDGPSHAAHFSFVPGPGKHFLRYNNAFILVDRQRERNSLNVKDGVPFETISLTTLYSHRHVFEDIFAEAHQIYQQSHEGKTVIYNSMGTMWQQFGDAKRKRPLDSVVLERGVKERIVEDMEAFISSRKWYLDRGIPYRRGYLLYGPPGTGKSSFIQAVAGHLDFNIAILNVSERGLTDDRLNHLLTKVPRRTVVLLEDVDVAFMNRKTPGADGYASASVTFSGLLNALDGVASAEERIIFLTTNHIERLDEALVRPGRVDMTVRLGEATEYQMEQLWDRFYADFDASGEAKQRFMAKARELGLVDAVSTASLQGLFLYNKDDTEGAIKMVESLTAGTRANGHAGVGGHVHVKEEEATSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU98</accession>
    <name>W6ZU98_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleoporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_90533</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NUP186/NUP192/NUP205 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686171.1">
        <property type="nucleotide sequence ID" value="XM_007687981.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZU98"/>
    <dbReference type="GeneID" id="19127706"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90533"/>
    <dbReference type="eggNOG" id="KOG1835">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002778_0_0_1"/>
    <dbReference type="OrthoDB" id="2019644at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021827">
        <property type="entry name" value="Nup186/Nup192/Nup205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11894">
        <property type="entry name" value="Nup192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1667" mass="187709" checksum="DCF7E842D0622922" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZW59</accession>
    <name>W6ZW59_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_24115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685399.1">
        <property type="nucleotide sequence ID" value="XM_007687209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZW59"/>
    <dbReference type="STRING" id="930090.W6ZW59"/>
    <dbReference type="GeneID" id="19120545"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24115"/>
    <dbReference type="eggNOG" id="ENOG502S8W8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_1_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF3">
        <property type="entry name" value="HTH-TYPE TRANSCRIPTIONAL REGULATOR RV1931C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="16"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="304" mass="33475" checksum="10232183FA21D2E2" modified="2014-04-16" version="1">MSAVADNTDGRVEQVKVLFALFDKYNTLDVAGPLEVLSRSLQDPKDPASKAFDCQFVGTAAAMTSVQGLTIKADMDYEDANNELDDFDVIIVPGGEGVFEVLKNKSEPLNLLTKYVELQEKNPIKERTILAIDVGALLLAQQGMLEGLAATTHPDYYVRLETICQDAARRDMSMRTDVMEERYVVNNARFDLGENPEENPYIIKKSREPQSPVEGTNMGHARRKSIARKGSNAWRDSRRRESIARRASMPLGGMRVITTGGVTAGLDASLYLVGSLASHDSALEVARVMQYTWVKGVTVDAIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWC4</accession>
    <name>W6ZWC4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_57578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685337.1">
        <property type="nucleotide sequence ID" value="XM_007687147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWC4"/>
    <dbReference type="GeneID" id="19124729"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_57578"/>
    <dbReference type="eggNOG" id="ENOG502RIMR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093251_0_0_1"/>
    <dbReference type="OrthoDB" id="3796633at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="183" mass="20310" checksum="F9DE1F3A9D46610A" modified="2014-04-16" version="1" fragment="single">TTTVDFFLPAPIRSEYRVISTTLANKYYSCLCLFLVLVFAIAEFEQPGWFPRPEELSSAVIGFLGVGTIISLVVALSEYVETHTWPWEDDGFVWPWEALLWRGTIYNDEALDDSVAAHSGSYGVQVSRQVGTKKSDCSEHEQASKRPDMIIPPTNFLPGGLRQKHLSPPITHPSGLLGESPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZC1</accession>
    <name>W6ZZC1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trafficking protein particle complex subunit 6B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_2165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684390.1">
        <property type="nucleotide sequence ID" value="XM_007686200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZC1"/>
    <dbReference type="STRING" id="930090.W6ZZC1"/>
    <dbReference type="GeneID" id="19120097"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2165"/>
    <dbReference type="eggNOG" id="KOG3316">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076409_0_1_1"/>
    <dbReference type="OrthoDB" id="941624at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14944">
        <property type="entry name" value="TRAPPC6A_Trs33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="27921" checksum="18C0737F4EA29F42" modified="2014-04-16" version="1">MAQANPSVPSETSPPYVDPTFSLINTSCLDLLLIELVPMAYRITADLAAREEEWIHGTATSAASPSARPKQLAGSPGNDAASTVAARTEGGGHVGVAGTVDEEDSREAVFHRLEALGYRVGLGVVERFSRDAPRPTTPLDCIKFLCKDLWTLLFRKQIDNLKTNHRGIYVLTDNTFKPLGRMSFDTKKYDASMQAALVAQTGDPALGREANSQARVQPFLYFPAGLIRGCLAALGIQASVTAESVALPGATFQIRTVGANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2D8</accession>
    <name>W7A2D8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Elongin-C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_32500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683287.1">
        <property type="nucleotide sequence ID" value="XM_007685097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2D8"/>
    <dbReference type="STRING" id="930090.W7A2D8"/>
    <dbReference type="GeneID" id="19122122"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32500"/>
    <dbReference type="eggNOG" id="KOG3473">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130038_1_0_1"/>
    <dbReference type="OrthoDB" id="249087at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18321">
        <property type="entry name" value="BTB_POZ_EloC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000035">
        <property type="entry name" value="Elongin C transcription elongation factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039948">
        <property type="entry name" value="ELC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20648">
        <property type="entry name" value="ELONGIN-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="6">
        <location>
            <begin position="9"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="102" mass="11432" checksum="27C6BE616BF0E794" modified="2014-04-16" version="1">MADEKPTEYVTLVSNDGYEFKLLRSAACIAGTIKKALDPMSGFRENAQNRVDLPTINGVVLEKVCEYLYYNQKHAESKDVSDMDIPPELCLELLIAADYLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3V5</accession>
    <name>W7A3V5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoporin Nup54 alpha-helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_81104</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682710.1">
        <property type="nucleotide sequence ID" value="XM_007684520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3V5"/>
    <dbReference type="STRING" id="930090.W7A3V5"/>
    <dbReference type="GeneID" id="19125802"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81104"/>
    <dbReference type="eggNOG" id="KOG0845">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027081_1_0_1"/>
    <dbReference type="OrthoDB" id="2538017at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024882">
        <property type="entry name" value="NUP58/p45/49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437">
        <property type="entry name" value="NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437:SF2">
        <property type="entry name" value="NUCLEOPORIN P58_P45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21121">
        <property type="entry name" value="Nup49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="44477" checksum="D4B69F8AF864D32B" modified="2014-04-16" version="1">MAGFGRSNSLSINTGGGGGLFGSNASTQQQTPQQPQQSGSLFGNLNKPTTTAPASAGLFGASTAQPSQPQSGGLFGGALGGNTQNQAQNITQSSGLFGGAQSKPSLFGASTQPVTTPSLFGNNTANQQNQTSTPSLFGSTQQQSQQQQQSTLGGGMNFPNRTNPLGGSTLGGTQMGASAQPVQLTLDSIRGTTRFNDLHPELQTLIQQFDEGVQRKINYCSQIRESLPGNERDISSIAPDVAYIETFLSTVEVGLDNDSANIAHLKSLVKKDAEDATLSFRAIENQRLPAQFHYRNNGNLTTSSAKTPATNALDDDDPTKPVDLMSYFDRRTDELGRTLDVYQRQIREIEAHLRTMEAGTVEKAQQLTGSRSAPRDQRRELVEALKAIEGAILDSAKKVGQVRDDVTKQTLGSVGAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W7A5A7</accession>
    <name>W7A5A7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyl carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_31441</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682135.1">
        <property type="nucleotide sequence ID" value="XM_007683945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A5A7"/>
    <dbReference type="STRING" id="930090.W7A5A7"/>
    <dbReference type="GeneID" id="19121868"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31441"/>
    <dbReference type="eggNOG" id="KOG1748">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_0_0_1"/>
    <dbReference type="OrthoDB" id="448946at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099128">
        <property type="term" value="C:mitochondrial [2Fe-2S] assembly complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000035">
        <property type="term" value="F:acyl binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000003">
        <property type="entry name" value="Acyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002148">
        <property type="entry name" value="PRK00982.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="ACYL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863:SF28">
        <property type="entry name" value="ACYL CARRIER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 14" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Carrier" evidence="15">
        <location>
            <begin position="60"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC51301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="145" mass="16080" checksum="82F055FC28512408" modified="2014-04-16" version="1">MFRTALLRSARSAVRAAPRCQAAMARPVARSSFVQPKQITPSVYFQAVRCYAASAGLSRDEVTGRIMDLLKNFDKVNDTSKLNAESHFHNDLGLDSLDTVEVVMAIEEEFSIEIPDKEADAIHSVKQAVEYILAQPDDDMQEAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YM77</accession>
    <name>W6YM77_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_47625</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964173">
        <property type="protein sequence ID" value="EUC40342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693133.1">
        <property type="nucleotide sequence ID" value="XM_007694943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YM77"/>
    <dbReference type="STRING" id="930090.W6YM77"/>
    <dbReference type="GeneID" id="19124367"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_47625"/>
    <dbReference type="eggNOG" id="ENOG502SKVQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_2_1"/>
    <dbReference type="OrthoDB" id="5329176at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF123">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886531" description="Rhodopsin domain-containing protein" evidence="7">
        <location>
            <begin position="23"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="226" mass="25490" checksum="E11F0DBBA9B4D217" modified="2014-04-16" version="1" fragment="single">MGLEDWTMIVATLLTLVHLSEALVGALEFNMGFKASKMSLKQVGSNIKLIVAMLVGYCAIVTLIKISILLVYRRLAYNKRFEDFCKRTIVVLATYQVIFTIVAAAQCVPLHKLWDFTNSVPGFCININAFYHASSSFHILIDIWILTLPIQLIRRIPRKPREKLALYINLGLGVVSMTASITRFRFLYVFTTSNDPIYGFVPVNTWSMVEVNVGILCATLPILRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6YN88</accession>
    <name>W6YN88_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ABC transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_107917</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964140">
        <property type="protein sequence ID" value="EUC40777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692704.1">
        <property type="nucleotide sequence ID" value="XM_007694514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YN88"/>
    <dbReference type="GeneID" id="19119147"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107917"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000913">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF11">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="542"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="586"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="654"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="685"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="772"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="804"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="215"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="546"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="869"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="465"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC40777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1111" mass="121422" checksum="55118A55AE5D9D9E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YN91</accession>
    <name>W6YN91_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_107899</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964140">
        <property type="protein sequence ID" value="EUC40782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692709.1">
        <property type="nucleotide sequence ID" value="XM_007694519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YN91"/>
    <dbReference type="STRING" id="930090.W6YN91"/>
    <dbReference type="GeneID" id="19119143"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107899"/>
    <dbReference type="eggNOG" id="ENOG502QT0U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120555_0_0_1"/>
    <dbReference type="OrthoDB" id="434648at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052032">
        <property type="entry name" value="ATP-dep_AA_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43585:SF2">
        <property type="entry name" value="ATP-GRASP ENZYME FSQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43585">
        <property type="entry name" value="FUMIPYRROLE BIOSYNTHESIS PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="22619" checksum="B23CACA701077E68" modified="2014-04-16" version="1">MTRLGFRNGIYHCEARIENSVVEWRFNSQGIPSLEPRQDHNGKPAESWLIEINTRPPGGDTCDFIETTWGVDYWALLLVTKLRDSSAWVHALSQPYRDGAQYYADKVWIIADWDPPKKGIWESGNITEELLQRRPDLAKHVSQHRTFAKKGDQLRHQSTGANSFVAYLHIFSRQNRPHLLELANEIRNELRIEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNE6</accession>
    <name>W6YNE6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_107710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964135">
        <property type="protein sequence ID" value="EUC40857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692634.1">
        <property type="nucleotide sequence ID" value="XM_007694444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNE6"/>
    <dbReference type="GeneID" id="19119102"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107710"/>
    <dbReference type="eggNOG" id="ENOG502SWE9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148854_0_0_1"/>
    <dbReference type="OrthoDB" id="5294241at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="123" mass="13600" checksum="608CC45DD8766854" modified="2014-04-16" version="1">MSSPTNSLYSTYSTESFSTRGSSCAYPSWPTGPSLDHRSPPSSYISDADLFGEDFDDDFSCPLLEEAPAPPRVPPMAQAFPILPPLYAQKKPKSERRRSSSGRKQRRTSKPMTPIAESPEQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ38</accession>
    <name>W6YQ38_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_111011</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">To endonucleases of group I introns of fungi and phage.</text>
    </comment>
    <dbReference type="EMBL" id="KI964298">
        <property type="protein sequence ID" value="EUC39633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693850.1">
        <property type="nucleotide sequence ID" value="XM_007695660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ38"/>
    <dbReference type="STRING" id="930090.W6YQ38"/>
    <dbReference type="GeneID" id="19119702"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111011"/>
    <dbReference type="eggNOG" id="ENOG502T28J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063898_0_0_1"/>
    <dbReference type="OrthoDB" id="3685236at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10445">
        <property type="entry name" value="GIY-YIG_bI1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006350">
        <property type="entry name" value="Intron_endoG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003647">
        <property type="entry name" value="Intron_nuc_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010896">
        <property type="entry name" value="NUMOD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003611">
        <property type="entry name" value="NUMOD3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01453">
        <property type="entry name" value="grpIintron_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07453">
        <property type="entry name" value="NUMOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07460">
        <property type="entry name" value="NUMOD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00497">
        <property type="entry name" value="IENR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64496">
        <property type="entry name" value="DNA-binding domain of intron-encoded endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="6">
        <location>
            <begin position="44"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC39633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="255" mass="29423" checksum="0BA210905707E376" modified="2014-04-16" version="1">MYLKSFCDEASSETSNQSSNSEINISPVYNLLNDRETILREFLNKSGIYLIHNNVNGKQYVGSGTDLAKRLATYYFPSRLVDNRYISNSILKYGHGNFSVVILYVLGNTDISIKKDIISKEQKYIDLYLPVLNLNPIAGSSMGFNHSEESKRLIKSKLGALNPMFNKEKSEEFVAHMYKDRKGSNNPMFGKTKSEETLAKIRKKVYVYDSNKQFIKCYDSIKFAVNDLHIAFETIKKYLDTDKTYKDKYFYSELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQJ3</accession>
    <name>W6YQJ3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RhoGAP-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_8615</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 11">ATCC 44560</strain>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="135"/>
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        <location>
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            <end position="198"/>
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    </feature>
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        <location>
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            <end position="1022"/>
        </location>
    </feature>
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        <location>
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            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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            <end position="646"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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        </location>
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        <location>
            <begin position="1"/>
            <end position="11"/>
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    </feature>
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            <end position="67"/>
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    </feature>
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        <location>
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        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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            <dbReference type="PROSITE" id="PS50238"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41687.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1163" mass="128807" checksum="415AA063FE91D8BC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSA0</accession>
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            <fullName evidence="5">Calpain catalytic domain-containing protein</fullName>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">ATCC 44560</strain>
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        <text evidence="1">Belongs to the peptidase C2 family.</text>
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    </dbReference>
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        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
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    </dbReference>
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        <location>
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            <end position="470"/>
        </location>
    </feature>
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        <location>
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        <location>
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            <end position="719"/>
        </location>
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        <location>
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            <end position="795"/>
        </location>
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        <location>
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            <end position="852"/>
        </location>
    </feature>
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        <location>
            <begin position="853"/>
            <end position="863"/>
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    </feature>
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        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="917" mass="101231" checksum="7D526DCB2A810CED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSA5</accession>
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        <alternativeName>
            <fullName evidence="18">Peroxin-10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_41169</name>
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    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="KI964159">
        <property type="protein sequence ID" value="EUC40510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSA5"/>
    <dbReference type="STRING" id="930090.W6YSA5"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="6270329at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16527">
        <property type="entry name" value="RING-HC_PEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Putative Peroxisome biosynthesis protein (Peroxin-10)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PEX2/10"/>
    </dbReference>
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        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF0">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="20">
        <location>
            <begin position="334"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
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            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
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            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC40510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="385" mass="42341" checksum="DFB528C5CC2120C7" modified="2014-04-16" version="1">MAPSPPFAYPFAASPDIIRSHQKDAYFSGVLLEHLSSLVRKLYGARTAHTYLSETRVIGELLYLGLTTLIGNRTLGEEYTDIVQVESETGRLPALGRRAGYIVACILGPYVLGRALPAFRRRIRAKLEANLRWYARQQARAQMVAQEKGEKVQIRRPLGMRVQNYILQNLDTITSPSPVYAVSLATFYFSGSYYHLSKRLWGLRYIFTRQVAEGDNRAGYEVLGVLLVLQMAVQAYLHLHNTVTASSTAAAAAGGSGHPHGTSVIVGGGAEVSLDPNAYSANNALLFDAATPAVPTAAASDVQKWTHTPPTDKPRYELGDEETMEWIGGGNRKCTLCLEEMKDPSVTTCGHVFCWTCIGDWAREKPECPLCRQACLVQHVLPLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSB9</accession>
    <name>W6YSB9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_108598</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964158">
        <property type="protein sequence ID" value="EUC40520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694764.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_108598"/>
    <dbReference type="eggNOG" id="ENOG502S731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="5204190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF13">
        <property type="entry name" value="MFS GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="497"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="60218" checksum="073561000090EF6E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSE4</accession>
    <name>W6YSE4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964157">
        <property type="protein sequence ID" value="EUC40540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692951.1">
        <property type="nucleotide sequence ID" value="XM_007694761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSE4"/>
    <dbReference type="STRING" id="930090.W6YSE4"/>
    <dbReference type="GeneID" id="19128791"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9612"/>
    <dbReference type="HOGENOM" id="CLU_1618717_0_0_1"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="49"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="164" mass="18514" checksum="718BA78ACE252582" modified="2014-04-16" version="1">MFKAGFVQDIESGKILREEFCRDASTCTECDLIQCELVTVSLEKHLGAFDALSYVWGYTDVKERIKMDGKTIEVTLNLEAALRRVRNTEAAELVWVDALCINQRDVEEKNIQVMRMKDVYTKCGRVLVWLGDALMDRAEDGKNEVAVAVKAISFLKKSPQNCTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT31</accession>
    <name>W6YT31_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-xylanase</fullName>
            <ecNumber evidence="7">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_108012</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="KI964142">
        <property type="protein sequence ID" value="EUC40745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692740.1">
        <property type="nucleotide sequence ID" value="XM_007694550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT31"/>
    <dbReference type="GeneID" id="19119168"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108012"/>
    <dbReference type="eggNOG" id="ENOG502QSCW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020161_2_1_1"/>
    <dbReference type="OrthoDB" id="3055998at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF76">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886724" description="Beta-xylanase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="10">
        <location>
            <begin position="22"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="11">
        <location>
            <begin position="124"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="66"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="66"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC40745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="430" mass="44751" checksum="00CF5F54E3687CB4" modified="2014-04-16" version="1">MHFRDASIYMAVVGLTSTTALAAVAPFGQCGGVNYKGDSACASGWTCNKYNDWYSQCIPGGGVKPAASPSPSLTVSPSPAASPSPTATSASSSIVKPAPSASPSPSAGSGGNTPAPNVAGSGRNGAKCNLDAAFKAKGKKYVGVATDQYTLSAGKNKEVIVDNFGCVTPENSMKWDATERSEGQFTLDGANALVSFATGNGKLIRGHTTVWHSQLAPWVSQIRDKAKLEEVMVNHIKKLVGTYAGKIYAWDVVNEIFDEQGGFRSSVFYNVLGEGFVSTAFHAARQADPLAKLYINDYNLDGANYGKTKGMITHVKQWIAAGVPIDGIGSQSHVSSPGTLFPISGVPAALKALCDAAPECAVTELDINNGKPADWVTVFDACVDIKNCVGITVWGVSDTNSWIGAAGGPLLFDGSFQAKPSYNELCSALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUV5</accession>
    <name>W6YUV5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell death in tomato 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_7318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690244.1">
        <property type="nucleotide sequence ID" value="XM_007692054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUV5"/>
    <dbReference type="GeneID" id="19125248"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7318"/>
    <dbReference type="eggNOG" id="ENOG502T143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1421880_0_0_1"/>
    <dbReference type="OrthoDB" id="5226619at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886818" description="Cell death in tomato 1" evidence="1">
        <location>
            <begin position="21"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="20238" checksum="3F268ADC5E2C06AB" modified="2014-04-16" version="1">MQFTTTSAITLLAFASSAAASPLAARQDALQDWQVTDLAVSVPMGRPGSYPWGTLKANITDPNAINLGTSSDGSQMIVPAGSKGVNCEAKWYINGDSPIGRAWPCDATSNGYWFMHVYEGTNGFSSSNFDLKFTRVAEKIHLDTQYKATFEAKGHFDSRGGLGGVCSAGECNWGLLQSKKPFKITPSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV39</accession>
    <name>W6YV39_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_29809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964104">
        <property type="protein sequence ID" value="EUC41413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692065.1">
        <property type="nucleotide sequence ID" value="XM_007693875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV39"/>
    <dbReference type="GeneID" id="19121572"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29809"/>
    <dbReference type="HOGENOM" id="CLU_1731124_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="151" mass="16382" checksum="AED776555AFE97EB" modified="2014-04-16" version="1">MIPETQSTSAPEWRSRPTRAGTWVVSLLRTACRGRHHVLSQGAGHIGQPSLPPRFLYTHLQAQSLVHVPSACRGQGGMSTDPDLLPTWQPWLGHGVVAICLLRAASPHPRMQETAFAIMSCLIGCKPSRPQSANPLSAADVKMFFALDNVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVH6</accession>
    <name>W6YVH6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_10399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964369">
        <property type="protein sequence ID" value="EUC39509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693970.1">
        <property type="nucleotide sequence ID" value="XM_007695780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVH6"/>
    <dbReference type="GeneID" id="19118418"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10399"/>
    <dbReference type="HOGENOM" id="CLU_2549052_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="83" mass="9625" checksum="67891F8E0312526D" modified="2014-04-16" version="1" fragment="single">RVKPPPIHDQFKDNIELEDNGLYIEGFNSNEYEEEINDEEEEEDDDDNEYEIEEEGSASAVQADDKDVDMDVESKFEGFSDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX00</accession>
    <name>W6YX00_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gag1-like clamp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_8323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964075">
        <property type="protein sequence ID" value="EUC42048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691427.1">
        <property type="nucleotide sequence ID" value="XM_007693237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX00"/>
    <dbReference type="STRING" id="930090.W6YX00"/>
    <dbReference type="GeneID" id="19126211"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8323"/>
    <dbReference type="eggNOG" id="ENOG502SRCS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036307_1_0_1"/>
    <dbReference type="OrthoDB" id="5422958at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053274">
        <property type="entry name" value="Fluconazole_resistance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025124">
        <property type="entry name" value="Gag1-like_clamp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28065:SF1">
        <property type="entry name" value="DUF4050 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28065">
        <property type="entry name" value="FREQUENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13259">
        <property type="entry name" value="clamp_Gag1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gag1-like clamp" evidence="2">
        <location>
            <begin position="67"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="292" mass="32560" checksum="19DD731E3F0A50E9" modified="2014-04-16" version="1">MESNLSAARASRRFLDERIRNDWDYPDPAVEWSASDEQVRDAVDFRERYYGESESGDSDNEDQDGAPYKFDNPESIGDAVAHTREARKRRRRERMEREMKENEGLRIWVERRDVWTGAASVKKYGTGRQRNRPSSAAGYSSEEPTTTPAGSESQSATSAAAPETYDLVPVAPRLLDQNPIRASITPSAYSDIYQKIVVSSRTPSVPINLADMTKALVQGWKDADEWPPRVAAVDPLAGKKRVITGPPSNGNHGGFIARHPHLEKGVDGMKRILHLNVQHNHENDHAQGGKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYL7</accession>
    <name>W6YYL7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">NEDD8-activating enzyme E1 catalytic subunit</fullName>
            <ecNumber evidence="8 10">6.2.1.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_6230</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.64" evidence="8 10"/>
    <dbReference type="EMBL" id="KI964004">
        <property type="protein sequence ID" value="EUC44442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689013.1">
        <property type="nucleotide sequence ID" value="XM_007690823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYL7"/>
    <dbReference type="STRING" id="930090.W6YYL7"/>
    <dbReference type="GeneID" id="19124888"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6230"/>
    <dbReference type="eggNOG" id="KOG2015">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013325_13_1_1"/>
    <dbReference type="OrthoDB" id="10255449at2759"/>
    <dbReference type="UniPathway" id="UPA00885"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01488">
        <property type="entry name" value="Uba3_RUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.520:FF:000001">
        <property type="entry name" value="NEDD8-activating enzyme E1 catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.20">
        <property type="entry name" value="Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014929">
        <property type="entry name" value="E2-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030468">
        <property type="entry name" value="Uba3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF6">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08825">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01181">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="E2 binding" evidence="11">
        <location>
            <begin position="356"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC44442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="440" mass="49035" checksum="DAB8457A366591B1" modified="2014-04-16" version="1">MAVNVNDMGAASTANPRARWKYLDRFLTRKGPFTDEDSFMAGEQVIEYLSNLKVLVIGAGGLGCEILKNLALSGFKDIHVIDMDTIDVSNLNRQFLFRASDVGKYKAETAAAFVEKRVKGVKITPYCGKIQDKDEAYYMQFGLIVCGLDSIEARRWINATLVGMVDENDPDSMKPLIDGGTEGFKGQARVIFPTMTSCIECQLDMHAPRAAVPLCTLATIPRQPQHCIEWAHIIAWEEERKDITLDTDDPEHITWLFNKATARAKEFNIDGVTYSMTQGVVKNIIPAIASTNAIVAASCCNEAFKVATNSNPFLGYPGMDNYMMYTGDDSVYTYTFEHQKKDDCPVCGAGNIARPLQVLPGITLQEFIEGLAERPEAQLKKPSIRTGEKSLYMQLAGLEEQTRPNLEKKMVDLVEEGEELLITDKSFPTQFKYKVVWASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYY4</accession>
    <name>W6YYY4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-methylcitrate dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_107996</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpD family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964142">
        <property type="protein sequence ID" value="EUC40739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692734.1">
        <property type="nucleotide sequence ID" value="XM_007694544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYY4"/>
    <dbReference type="GeneID" id="19119162"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107996"/>
    <dbReference type="eggNOG" id="ENOG502SKUA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021803_1_0_1"/>
    <dbReference type="OrthoDB" id="10055203at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047547">
        <property type="term" value="F:2-methylcitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4100.10">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.120">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012705">
        <property type="entry name" value="2Me_IsoCit_deHydtase_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036148">
        <property type="entry name" value="MmgE/PrpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042183">
        <property type="entry name" value="MmgE/PrpD_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042188">
        <property type="entry name" value="MmgE/PrpD_sf_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005656">
        <property type="entry name" value="MmgE_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045337">
        <property type="entry name" value="MmgE_PrpD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045336">
        <property type="entry name" value="MmgE_PrpD_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02330">
        <property type="entry name" value="prpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943:SF15">
        <property type="entry name" value="DEHYDRATASE (PRPD), PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19305">
        <property type="entry name" value="MmgE_PrpD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03972">
        <property type="entry name" value="MmgE_PrpD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103378">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MmgE/PrpD N-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="MmgE/PrpD C-terminal" evidence="4">
        <location>
            <begin position="286"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="54312" checksum="BD1BC307D6D96ECD" modified="2014-04-16" version="1">MSSTPYDQVIIDIKNYVFDYHIGDEDVFNCARMALLDAMGCAIETISSSAECGKLLGPFDSITVNRNGFRLPGTSYLLDPLKGAFDMATIIRYLDHNDAIAGADWGHPSDNLGAILAVADWQSHRIARGDIVHTGPKLTMRTLLTAMIKAYEIQGCFLLRNAFNKHGLDHVILVKLASTAVVAWLLGLTEEETMAAISHVWMDGHPLRTYRHGTNTIPRKGWAAGDACMRAVQLVLFAQTGQPGSKTVLTEPRWGFYDTLFGGQPFQFPIPYDSWVIRNTIFKVMPVEGHGIAAVQAALQHGNLMRAQGLSPDKHIKRVDIRTTAAAILIIDKQGHLHNAADRDHCMQYMVALALLKGAAPESNDYKSESPWACDERLSELRSNIHLTEDKNLTKDYLDLDKKSLASGVTITFTDDTISEEIFVEFPVGHVQSADTKKMVQEKFIKNMKLQFSTQEIERVIKAVEMPDLMISEFLGLFAKGRHNIQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYZ7</accession>
    <name>W6YYZ7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_27113</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688877.1">
        <property type="nucleotide sequence ID" value="XM_007690687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYZ7"/>
    <dbReference type="GeneID" id="19121065"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27113"/>
    <dbReference type="HOGENOM" id="CLU_918235_0_0_1"/>
    <dbReference type="OrthoDB" id="3691936at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="331" mass="35499" checksum="AF2B374DA6F9F36D" modified="2014-04-16" version="1">MVEGLVLRSASKCAQSNCAHTATATATATATVTAPATANSQDDKGCKKRRIAGRTRGKRLLVLMNPLNAPGVVETQCSRPSINGQTGEPWWATCQASSSSANLSQCRYIDAGLQVAFPVTTPAKALPAVPQPTSVLLSSCATSTHLQGCAAAASQTNHHAPVAVVMPAWPPLPRRPFWGYSTHALDDTQPQATLAALLRIVTDCFPWVLCNPTVETSCMHADDAHAEKPPCPWRPFLLDRQVDPRQSARPPAGHAESYSVTYKAKMPMEPRLSLLPTLPTTTPPALFPTPGSYPQPRGYCRLVICAPNQDWHRLLVLLPSDSTRIGGETMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ22</accession>
    <name>W6YZ22_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_27059</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688826.1">
        <property type="nucleotide sequence ID" value="XM_007690636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ22"/>
    <dbReference type="STRING" id="930090.W6YZ22"/>
    <dbReference type="GeneID" id="19121056"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27059"/>
    <dbReference type="eggNOG" id="ENOG502QT4U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014765_0_0_1"/>
    <dbReference type="OrthoDB" id="16911at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036121">
        <property type="term" value="F:double-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061749">
        <property type="term" value="F:forked DNA-dependent helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000403">
        <property type="term" value="F:Y-form DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032042">
        <property type="term" value="P:mitochondrial DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18032">
        <property type="entry name" value="DEXHc_RE_I_III_res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18799">
        <property type="entry name" value="SF2_C_EcoAI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050742">
        <property type="entry name" value="Helicase_Restrict-Modif_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47396:SF1">
        <property type="entry name" value="ATP-DEPENDENT HELICASE IRC3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47396">
        <property type="entry name" value="TYPE I RESTRICTION ENZYME ECOKI R PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="76"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="297"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="686" mass="75964" checksum="7C8F87ED9A30F168" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZH2</accession>
    <name>W6YZH2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_37446</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688730.1">
        <property type="nucleotide sequence ID" value="XM_007690540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZH2"/>
    <dbReference type="GeneID" id="19123247"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37446"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF62">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="61"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="488" mass="53516" checksum="D8B8A87995311B43" modified="2014-04-16" version="1">MAGPNYNHDAEKDVPLHIDDVEPSEKELAQKGTPEGADYTGAVAKSDPAEIALVRKLDMRVMPALFAMYFLNKLDQNAIANARLDGLEKDLGLRGTQYNTCISILYVGYLFAQIPSNMLMSSRKVRPSLYMAICCTVWGCVAALTSLVKNYTGLVLVRFFLGFVEAPFYPGALYILSMFYTRKEIATRVAILYAGNIFAVSFAGLIAAAVFATLSDKHGMHGWQWLFIIEGVVTVGVSIICIFLLPDEPLTTKWLTPEQRQLAHDRIQRDTVGLEPSKGSRAGFMQALRDPRLYLLVFMQNMHLSATSFNQFFPTVVKSLGFSRTITLVLTAPPSLVAGVVGICIGISSGKYNDRTWHITAMMGLAVVGFAISASTLNVAARYVSCFLFASGVYSVNSVILGWVSGTLGQTTEKKAVSLSIVNVVSMASFIYTPYLYPESDGPKYIIAMSSNAAFSAACIASAWGLRIWLQVTNKRLRRDGVNVFYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZX4</accession>
    <name>W6YZX4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Haloacid dehalogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964121">
        <property type="protein sequence ID" value="EUC41079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692400.1">
        <property type="nucleotide sequence ID" value="XM_007694210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZX4"/>
    <dbReference type="STRING" id="930090.W6YZX4"/>
    <dbReference type="GeneID" id="19123928"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40687"/>
    <dbReference type="eggNOG" id="ENOG502S19E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_3_0_1"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF3">
        <property type="entry name" value="HALOACID DEHALOGENASE, TYPE II (AFU_ORTHOLOGUE AFUA_2G07750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="32108" checksum="B7C34E7BC912D039" modified="2014-04-16" version="1">MVISPTTRALFFDVFGTCVDWRSTVVGELEAQAHFALNLATVSSQVRFTASDMTTQDWNKFAQQWRDGYKAFTRKLASDSSIPWKTVDEHYLETLRELVVQWHIEGLWNDEQLCAISLIWHRLDPWTDSAIGVSMLNKLFYTCTLSNGNLSLLEDLRTHTAIPFTHLFSAELFGTYKPSPRVYLGAADKLQLPPTQCAMVAAHLNDLRGAKNNGMQTIYVERPGEEEWDSEQIEKALLEGWVDLWIGSNESQGSFVTVAERLGIELSSYDEARRFSASTIATSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0D3</accession>
    <name>W6Z0D3_COCMI</name>
    <protein>
        <recommendedName>
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        <name evidence="4" type="ORF">COCMIDRAFT_101061</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC43380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0D3"/>
    <dbReference type="STRING" id="930090.W6Z0D3"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_101061"/>
    <dbReference type="eggNOG" id="KOG3041">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="10249920at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="term" value="P:ribose phosphate metabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ADP-sugar pyrophosphatase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NUDIX_hydrolase_dom"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="192"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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        <recommendedName>
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        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_5503</name>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="19124639"/>
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    </dbReference>
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            <begin position="284"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="403"/>
        </location>
    </feature>
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        <location>
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            <end position="479"/>
        </location>
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        <location>
            <begin position="549"/>
            <end position="646"/>
        </location>
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    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="578"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
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            <end position="616"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="646" mass="72057" checksum="A6D046E88A8B4ED1" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6Z0N2</accession>
    <name>W6Z0N2_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
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        <name evidence="3" type="ORF">COCMIDRAFT_100685</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
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        </location>
    </feature>
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        <location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
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    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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            <end position="569"/>
        </location>
    </feature>
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        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
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        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
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        <location>
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        </location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="521"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="569" mass="61158" checksum="380DFE4005999528" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1I1</accession>
    <name>W6Z1I1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Replication factor A protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_95159</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963981">
        <property type="protein sequence ID" value="EUC45612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687906.1">
        <property type="nucleotide sequence ID" value="XM_007689716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1I1"/>
    <dbReference type="STRING" id="930090.W6Z1I1"/>
    <dbReference type="GeneID" id="19128597"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95159"/>
    <dbReference type="eggNOG" id="ENOG502SBIR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141922_2_0_1"/>
    <dbReference type="OrthoDB" id="188186at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04479">
        <property type="entry name" value="RPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000271">
        <property type="entry name" value="Similar to ssDNA binding protein Ssb3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013970">
        <property type="entry name" value="Rfa2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114:SF1">
        <property type="entry name" value="REPLICATION PROTEIN A 14 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114">
        <property type="entry name" value="REPLICATION PROTEIN A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08661">
        <property type="entry name" value="Rep_fac-A_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="11780" checksum="58CA17B6F6D24026" modified="2014-04-16" version="1">MDHPQTPRIIAPHLSEFQHRIVRILGKVVQLRGETAVIDAGGNIDVILTRDSHLTVGHAVEIIGKVDQNLHVKVQAATDFGTGVDFDAAMAVVDVTHRYKEIFYDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1K6</accession>
    <name>W6Z1K6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_94921</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687832.1">
        <property type="nucleotide sequence ID" value="XM_007689642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1K6"/>
    <dbReference type="STRING" id="930090.W6Z1K6"/>
    <dbReference type="GeneID" id="19128544"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94921"/>
    <dbReference type="eggNOG" id="ENOG502S8J5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_801643_0_0_1"/>
    <dbReference type="OrthoDB" id="5397628at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886522" evidence="3">
        <location>
            <begin position="22"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="186"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="347" mass="39178" checksum="7E237D0887BAE04A" modified="2014-04-16" version="1">MGAILSLPFTLLNFLLPFTRAGTPLSQDLLHTAILCGTLYFAPQIGEWYNARQQGAHRTPPDQPDAQEPSNQPTDNNLPNTNTQAAPDPPLDERLILQDDDDPDTHPGAARPRAPTPPPAPRHQAHVEDDEHRDPFAPGPANPPPQQQPARAPTHRTVGTKKAKSLARRDQQRAYNEWLRQEAEIRRRQEDEGREEREAALALERERRAAAEEVIRAKEREEREALKREREREAKEEAERRERVVGYVRGRIEEVGCVDLVEAAWKEGKDRVWVERLVRASGLLGQLTTEGKSVMLTARDWLVRIDQTIVDKAYAEAERFGLEHGGKVGFEEFGSILENVVLQGVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1P1</accession>
    <name>W6Z1P1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_40259</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI964096">
        <property type="protein sequence ID" value="EUC41564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691903.1">
        <property type="nucleotide sequence ID" value="XM_007693713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1P1"/>
    <dbReference type="STRING" id="930090.W6Z1P1"/>
    <dbReference type="GeneID" id="19123847"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40259"/>
    <dbReference type="eggNOG" id="KOG1591">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058132_0_4_1"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000027">
        <property type="entry name" value="Oxidoreductase, 2OG-Fe(II) oxygenase family family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="7">
        <location>
            <begin position="96"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="343" mass="37861" checksum="17C8D162A78D0C3B" modified="2014-04-16" version="1">MRSPTSPTPPLQQSQLSFSSIAQYVFLAGLAYVLAGAPLSSFLNSSSSGSENSYNVKAREGKVVDVRTLESLVIPETNLSCAEHRYKGVYVLSRDPLVIYIEGFLGEGEGKEVVGLSTPLFKPSTIWTSGRESLNPTIRLSEKAPLPRSETVKCIEDRARTFQGWRPNTFVEKLWTQRYGAGGHYTYHYDWSTATKHSGRVSSFMVYVDGQCEGGGTHFPRLERPSDKSWCRFIECDVQGAYGSLSASKPATEGNDDAENETSTAKIPQDRAQEDLEKGVIFKPIPGNAVYWENIRSDGSGFAESWHAGLPVIKGEKIGLNIWSWMVDGYVPPLDQAQQEKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1Q0</accession>
    <name>W6Z1Q0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_99701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964017">
        <property type="protein sequence ID" value="EUC43885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689624.1">
        <property type="nucleotide sequence ID" value="XM_007691434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1Q0"/>
    <dbReference type="GeneID" id="19129516"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99701"/>
    <dbReference type="eggNOG" id="ENOG502T5NP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153331_0_0_1"/>
    <dbReference type="OrthoDB" id="3882258at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="139" mass="15468" checksum="92D6877AA70EC8F1" modified="2014-04-16" version="1">MSAAAGAPPPPPPPPGPFARGNPFDDLPAELLLIIYEYVGNSNLINLALAIYPTFQRHNLSPELTPSTLAHMLNLSHRPPMYPGIVYMPAELWLCVARYLEPADILSMMFTFGAVFGQPLTPSTRDRLRVWSRRLREKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1Q6</accession>
    <name>W6Z1Q6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Membrane anchor Opy2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_38455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964023">
        <property type="protein sequence ID" value="EUC43653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689840.1">
        <property type="nucleotide sequence ID" value="XM_007691650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1Q6"/>
    <dbReference type="STRING" id="930090.W6Z1Q6"/>
    <dbReference type="GeneID" id="19123470"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38455"/>
    <dbReference type="eggNOG" id="ENOG502QV8M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030352_0_0_1"/>
    <dbReference type="OrthoDB" id="2402916at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018571">
        <property type="entry name" value="Membrane_anchor_Opy2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09463">
        <property type="entry name" value="Opy2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane anchor Opy2 N-terminal" evidence="3">
        <location>
            <begin position="19"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="483" mass="51776" checksum="24C3700AF5857529" modified="2014-04-16" version="1">MSIRALRDAENVFRIEKRCKLCEQAPLSCEGIKCPANQVCVQNSRTCDECASVNCQVDPTIAPPEPSKPNVGAIAGGVIGGILAVAILTFVVWKYCLKGKRRPISQQPEWSHVDVVEQEKDNDFESRRSARASTHTVASMASSVLTRASNIIQIAYIPGVTNRSGNPGSPDLLVPPVPPIPSMSPSSGKSSPYASADQHFFVPDFRDSMMSSSTAGRTSIAPSLAQRGSVASTMYRQNAIVSPLPAQTIVRGKAAVVSVKSTGSTSPGETPTQTPPIPSIDPKHSLKPIRIQMPGISPANSVRSTAQLGPVKALHITKKKSSETTPPKSSSSTTDTERTLVNSPDRRASAGRPLTASSTLSSNDGREHSRARRGSLASDTEDDEDDHTRANQTLLGKSTNRDSDVTEFQDTTPHMDNSPFSDNSSLDNPRPMMSHRITSYDPSSGLRTPMTPIVEESSASKRGSTISNRRDTSPFADTNRSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1S5</accession>
    <name>W6Z1S5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_99518</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689575.1">
        <property type="nucleotide sequence ID" value="XM_007691385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1S5"/>
    <dbReference type="STRING" id="930090.W6Z1S5"/>
    <dbReference type="GeneID" id="19129488"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99518"/>
    <dbReference type="eggNOG" id="KOG3328">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_12_1_1"/>
    <dbReference type="OrthoDB" id="46529at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000033">
        <property type="entry name" value="acyl-coenzyme A thioesterase 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="54"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="161" mass="17464" checksum="2754303728AD9AB7" modified="2014-04-16" version="1">MTALKFVRYVWESFRANSGLEPRLLDGLRVTSAVPGRVKFELDIKKEHTNRLSILHGGTIASMVDLGGSLAVASRGLFATGVSTDLNVTYLSSGGKVGDLIKAEVSCDKFGKTLAFTSINFSNSKGEIFARGSHTKYVALAWKDPNNIVEELSPKPSEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2F2</accession>
    <name>W6Z2F2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycoside hydrolase family 3 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_6478</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964010">
        <property type="protein sequence ID" value="EUC44155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689297.1">
        <property type="nucleotide sequence ID" value="XM_007691107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2F2"/>
    <dbReference type="GeneID" id="19124968"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6478"/>
    <dbReference type="eggNOG" id="ENOG502SSS1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1349357_0_0_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="19444" checksum="C0F40F312621781B" modified="2014-04-16" version="1">MLHGASTTGDAKLVRCPKRTLERLRHLNEAEIITLFTPIVPHPPSTTLAKDMDPFEPLGRVLPRKVRHVPYRLDHGKTETHADFLPSSGAVIIVICATANVLRYDAHAFEKQLQFARGIAKDIKENNTIASIPSAVLLISDDAAGRGYVDAICDLPAVITANDYTAAALNNAVQVLFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2N2</accession>
    <name>W6Z2N2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial distribution and morphology protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mitochondrial inheritance component MDM12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MDM12</name>
        <name evidence="12" type="ORF">COCMIDRAFT_94022</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion outer membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="9">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MDM12 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963973">
        <property type="protein sequence ID" value="EUC46012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687481.1">
        <property type="nucleotide sequence ID" value="XM_007689291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2N2"/>
    <dbReference type="STRING" id="930090.W6Z2N2"/>
    <dbReference type="GeneID" id="19128371"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94022"/>
    <dbReference type="eggNOG" id="ENOG502S3PB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026794_0_0_1"/>
    <dbReference type="OrthoDB" id="3356905at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21672">
        <property type="entry name" value="SMP_Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03104">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027532">
        <property type="entry name" value="Mdm12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26544">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="1"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="65"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="215"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC46012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="424" mass="46469" checksum="AC69EE985207255D" modified="2014-04-16" version="1">MSIDINWDTITGGAEGSARAEKIRAFIHDRFQQVTLPRFIRSVHVHSFDFGSVAPEIEIKDICDPLPDFYEDDEDYPDEQGGEPEPEPDDEALHADDKLREGGRETANPQRLHPDHANVRPSQSRTKSSNKRGSLAPNEIGSPFFPGALTPGIPGGTSNMNYFHLPLSAGLSGAATPLAAVAGAHLHTWLDNPHGRPATPTNMRLRHAASVNSLTLTPQSHPDPSSRPSSRHQQDEPKRPSFTGSDDGLSQDSYVRTPSASPNRMHEKSPDDIQVVTHVQYSGDIKMSLTAEILLDYPMPSFVGIPLKLNITGLTFDGVAILAYIKKRAHFCFLSPDDADALVGSDTGFNGLQTDARGQNPRPVQRPKIGGLLENIKVESEIGGQGSGKQVLKNVGKVESFVLEQVRRIFEDEFVYPSFWTFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2P9</accession>
    <name>W6Z2P9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_39963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964080">
        <property type="protein sequence ID" value="EUC41929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691552.1">
        <property type="nucleotide sequence ID" value="XM_007693362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2P9"/>
    <dbReference type="GeneID" id="19123781"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39963"/>
    <dbReference type="eggNOG" id="ENOG502SXCJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106851_0_0_1"/>
    <dbReference type="OrthoDB" id="3476937at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="200" mass="22546" checksum="9EDE6CD859042B33" modified="2014-04-16" version="1">MQKTLKSSRSQDLARLTHPYTLLMTIPTGPGSATTISYWAPPEFQPCHFQLRISLKPAQIQLVQSHEDHGIVCIAAREPDLASFFRKKLEYLQTSSHDAKMVSKLVVNLRCDEVNKGVELQIFSVQIFGDEGGNLVSEGCNLLWKWTKEQSPYRKSGFWDHKLAQVLVDAEWTAGEGVVILAKGVDEEEYERVVKGEIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z384</accession>
    <name>W6Z384_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_98356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689114.1">
        <property type="nucleotide sequence ID" value="XM_007690924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z384"/>
    <dbReference type="GeneID" id="19129241"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98356"/>
    <dbReference type="HOGENOM" id="CLU_2891897_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="63" mass="7256" checksum="2F0B799D98A55298" modified="2014-04-16" version="1" fragment="single">KPIALLQVTEDLNLFLWVYDGYGGMQFLFRVILSSIPDRIKVKIDLNLRFLGDFADLNPAEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3B2</accession>
    <name>W6Z3B2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_98855</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964009">
        <property type="protein sequence ID" value="EUC44198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689283.1">
        <property type="nucleotide sequence ID" value="XM_007691093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3B2"/>
    <dbReference type="STRING" id="930090.W6Z3B2"/>
    <dbReference type="GeneID" id="19129346"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98855"/>
    <dbReference type="eggNOG" id="KOG0274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_103_1_1"/>
    <dbReference type="OrthoDB" id="5580488at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043224">
        <property type="term" value="C:nuclear SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140299">
        <property type="term" value="F:molecular sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990756">
        <property type="term" value="F:ubiquitin-like ligase-substrate adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046686">
        <property type="term" value="P:response to cadmium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd22147">
        <property type="entry name" value="F-box_SpPof1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000016">
        <property type="entry name" value="E3 ubiquitin ligase complex SCF subunit sconB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000715">
        <property type="entry name" value="F-box protein MET30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051075">
        <property type="entry name" value="SCF_subunit_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872">
        <property type="entry name" value="UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872:SF9">
        <property type="entry name" value="UBIQUITIN-BINDING SDF UBIQUITIN LIGASE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="8">
        <location>
            <begin position="152"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="337"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="377"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="456"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="579"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="604"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="644"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="238"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="528"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="528"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="681" mass="76017" checksum="61485EDB7AAF3099" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3J1</accession>
    <name>W6Z3J1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_104159</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964070">
        <property type="protein sequence ID" value="EUC42194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693118.1"/>
    </dbReference>
    <dbReference type="GeneID" id="19118453"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104159"/>
    <dbReference type="eggNOG" id="KOG0065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_35_0_1"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000881">
        <property type="entry name" value="ABC multidrug transporter A-1"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
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                <person name="Schackwitz W."/>
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                <person name="Dhillon B."/>
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</entry>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5S8</accession>
    <name>W6Z5S8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA topoisomerase</fullName>
            <ecNumber evidence="3 7">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_95795</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 7"/>
    <dbReference type="EMBL" id="KI963986">
        <property type="protein sequence ID" value="EUC45325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688143.1">
        <property type="nucleotide sequence ID" value="XM_007689953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5S8"/>
    <dbReference type="STRING" id="930090.W6Z5S8"/>
    <dbReference type="GeneID" id="19128724"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95795"/>
    <dbReference type="eggNOG" id="KOG1956">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002929_1_1_1"/>
    <dbReference type="OrthoDB" id="430051at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031422">
        <property type="term" value="C:RecQ family helicase-topoisomerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.290.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.140:FF:000005">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF21">
        <property type="entry name" value="DNA TOPOISOMERASE 3-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPO_IA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="9">
        <location>
            <begin position="3"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="10">
        <location>
            <begin position="166"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="530"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="530"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="549"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="665" mass="74300" checksum="1AC892357639A34B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z615</accession>
    <name>W6Z615_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_5418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963985">
        <property type="protein sequence ID" value="EUC45415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688074.1">
        <property type="nucleotide sequence ID" value="XM_007689884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z615"/>
    <dbReference type="GeneID" id="19124608"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5418"/>
    <dbReference type="eggNOG" id="KOG4525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009601_1_0_1"/>
    <dbReference type="OrthoDB" id="74460at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053002">
        <property type="entry name" value="Metalloproteinase_M10B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021917">
        <property type="entry name" value="Unchr_Zn-peptidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21054:SF2">
        <property type="entry name" value="MIP04191P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21054">
        <property type="entry name" value="ZINC METALLOPROTEINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12044">
        <property type="entry name" value="Metallopep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="748" mass="83162" checksum="40BEB67DFFE5DDFB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6L7</accession>
    <name>W6Z6L7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_36842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963984">
        <property type="protein sequence ID" value="EUC45463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688035.1">
        <property type="nucleotide sequence ID" value="XM_007689845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6L7"/>
    <dbReference type="GeneID" id="19123122"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36842"/>
    <dbReference type="eggNOG" id="ENOG502S5DH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084254_0_0_1"/>
    <dbReference type="OrthoDB" id="4510061at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="179" mass="20142" checksum="57A4D6C01016A720" modified="2014-04-16" version="1">MSDGLNDARAMRVAEIMTDFRNLQHYLVQLRATPTAEEYYLDGYSLLRQCTSEAQAILQTPFASSTPSGTGDLEYEKRQLRAIIVDAAVRRFQCQRAYLRANAGLRWMNSRQSILRGQKPNASHMAALQQADATLSNELMAMTDAYIDNTLRAADAAQGKWLNEDPSLAQIQQIILSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6R7</accession>
    <name>W6Z6R7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_48954</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS25 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963983">
        <property type="protein sequence ID" value="EUC45513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688008.1">
        <property type="nucleotide sequence ID" value="XM_007689818.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6R7"/>
    <dbReference type="STRING" id="930090.W6Z6R7"/>
    <dbReference type="GeneID" id="19124424"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_48954"/>
    <dbReference type="eggNOG" id="KOG1767">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129470_4_0_1"/>
    <dbReference type="OrthoDB" id="10263513at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004977">
        <property type="entry name" value="Ribosomal_eS25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12850">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03297">
        <property type="entry name" value="Ribosomal_S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC45513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="96" mass="10424" checksum="7749F0670738D297" modified="2014-04-16" version="1" fragment="single">APAATGGKKQKKKWSKGKVKDKAQHAVVLDKTTNDKLQKDVQSYRLITVATLVDRLKINGSLARKALADLEANGQIKKVVGHSKLSIYTRAIGDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6U0</accession>
    <name>W6Z6U0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GPI inositol-deacylase winged helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687934.1">
        <property type="nucleotide sequence ID" value="XM_007689744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6U0"/>
    <dbReference type="GeneID" id="19128605"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95193"/>
    <dbReference type="HOGENOM" id="CLU_1839843_0_0_1"/>
    <dbReference type="OrthoDB" id="3944243at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="1">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="140" mass="15949" checksum="FAD11111F2CE3E3B" modified="2014-04-16" version="1" fragment="single">MLQWLVAAARPLKLYEITAAVAVPSYETYLETERWVPHSEWLSDVRLEGPLHTPEWLRKLCGPLVRLTSSKEEISLAHFSLKEYLTSGKLGNSSNAQVQKYNVALADAHAHIATVSLTYLCSQELSKPFRNRQELDELRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6W0</accession>
    <name>W6Z6W0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687939.1">
        <property type="nucleotide sequence ID" value="XM_007689749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6W0"/>
    <dbReference type="GeneID" id="19128603"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95190"/>
    <dbReference type="HOGENOM" id="CLU_3124730_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887225" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="50" mass="5582" checksum="939E3FF76F41ED89" modified="2014-04-16" version="1" fragment="single">LSSRLSLTSWPTLSCFLLLPWVAKVKRGIQTCAVFWPTCTSTHTPLSSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7D4</accession>
    <name>W6Z7D4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_100607</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RING-box family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964027">
        <property type="protein sequence ID" value="EUC43484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689981.1">
        <property type="nucleotide sequence ID" value="XM_007691791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7D4"/>
    <dbReference type="STRING" id="930090.W6Z7D4"/>
    <dbReference type="GeneID" id="19117709"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100607"/>
    <dbReference type="eggNOG" id="KOG1493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115512_0_1_1"/>
    <dbReference type="OrthoDB" id="1681166at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd16456">
        <property type="entry name" value="RING-H2_APC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000111">
        <property type="entry name" value="Anaphase-promoting complex subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024991">
        <property type="entry name" value="RING-H2_APC11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12861">
        <property type="entry name" value="zf-ANAPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC43484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="106" mass="12219" checksum="D3C483D6EF9B6F97" modified="2014-04-16" version="1">MKVTIREWNAVAAWHWDMPDDDVCGICRNPYDSTCSKCKFPGDECPLLLGECNHSFHMHCIFDWLKQESSLEKCPMCRQPFKSKSQDAPTVTETPRQIQEPDTSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7G5</accession>
    <name>W6Z7G5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_111003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964297">
        <property type="protein sequence ID" value="EUC39636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693847.1">
        <property type="nucleotide sequence ID" value="XM_007695657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7G5"/>
    <dbReference type="GeneID" id="19119699"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111003"/>
    <dbReference type="HOGENOM" id="CLU_2454382_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="89" mass="10188" checksum="57E74C3633699711" modified="2014-04-16" version="1">MQDPQTGLPCCYVCRAPCIPLNSQSTSYIHEQLPFLHIQKLPRSEILYKPQCRARMPAELTLLIVIFVLLGLFATHRNIKRYNCNSIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7N8</accession>
    <name>W6Z7N8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_94000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963973">
        <property type="protein sequence ID" value="EUC46025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687486.1">
        <property type="nucleotide sequence ID" value="XM_007689296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7N8"/>
    <dbReference type="STRING" id="930090.W6Z7N8"/>
    <dbReference type="GeneID" id="19128363"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94000"/>
    <dbReference type="eggNOG" id="ENOG502QTJK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019940_4_1_1"/>
    <dbReference type="OrthoDB" id="3828420at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06434">
        <property type="entry name" value="GT2_HAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="464" mass="54036" checksum="B2C4E986474EE7BA" modified="2014-04-16" version="1">MFPFSLTLFPNWSWLCIFVVLFLFRYVRLWVNLASNWTYTPMQPVDDPTITSKDMTVIIPTVAEDLQQLKETVQSAYRLEPFELLLVTPDSRVKRVYQMVEELGSPKIIQVLSVSQANKRRQLCRAIPEVETKITLLLDDDVWLPEKFTKWILAPFEDPRVGGVGTNQQIRRFNRSNIWEFLGAIYLVRRNFDCTACNWIDGGLPCLSGRAVAYRSEILQDPNFTYGFTHETWGSDHFLNADDDNFITRWLFSHNWRIQMQNHRECEVETTLEDDSKYLRQCLRWVRSNWRSNLTSLTEGYMWMRYPWSLYAVFQTTVTQWAFLLDCALFASAYFALCETGYYPADAGQLSRADKWQRSLLWTLFIAHWVFAKTIKLVPHLLRNPGDVRFVPISILFGYFHNLIKLYGCITVTETTWGTREGADADDNIRMLPIPPMAAITPPLTPPPGGRVLRERCAGFPIMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7T7</accession>
    <name>W6Z7T7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-N-acetylglucosamine diphosphorylase</fullName>
            <ecNumber evidence="4">2.7.7.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_89043</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="4"/>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685693.1">
        <property type="nucleotide sequence ID" value="XM_007687503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7T7"/>
    <dbReference type="STRING" id="930090.W6Z7T7"/>
    <dbReference type="GeneID" id="19127398"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89043"/>
    <dbReference type="eggNOG" id="KOG2388">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011580_0_0_1"/>
    <dbReference type="OrthoDB" id="17395at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050032">
        <property type="term" value="F:L-rhamnonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03327">
        <property type="entry name" value="MR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04193">
        <property type="entry name" value="UDPGlcNAc_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000075">
        <property type="entry name" value="Probable UDP-N-acetylglucosamine pyrophosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000005">
        <property type="entry name" value="Putative L-rhamnonate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023444">
        <property type="entry name" value="L-Rhamnon_dehydrat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011968">
        <property type="entry name" value="PRK15440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952:SF2">
        <property type="entry name" value="LD24639P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="UDP- GLUCOSE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00179">
        <property type="entry name" value="mandelate_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00006">
        <property type="entry name" value="rhamnonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="10">
        <location>
            <begin position="178"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="940" mass="103465" checksum="4B7611FA22F6D1D9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8I1</accession>
    <name>W6Z8I1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable electron transfer flavoprotein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_4569</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9 10">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963968">
        <property type="protein sequence ID" value="EUC46290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687140.1">
        <property type="nucleotide sequence ID" value="XM_007688950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8I1"/>
    <dbReference type="STRING" id="930090.W6Z8I1"/>
    <dbReference type="GeneID" id="19124289"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4569"/>
    <dbReference type="eggNOG" id="KOG3954">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034178_0_0_1"/>
    <dbReference type="OrthoDB" id="1715808at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000041">
        <property type="entry name" value="Electron transfer flavoprotein alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000001">
        <property type="entry name" value="Electron transfer flavoprotein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 9 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="11">
        <location>
            <begin position="37"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="264"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="278"/>
            <end position="282"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="295"/>
            <end position="302"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000089-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC46290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="349" mass="36513" checksum="7720F6281DB824B6" modified="2014-04-16" version="1">MFSVARQCALRTARTRLRQSQPVAVPQYSAFARLASTLAVLEQKDGKIVSQSLAAITAGTKIGGSITAFVAGNGVKAVAEEAAKAKGVEKVIYVENGAYDKSLPENFAPLLVENIKKGGYTHVIAGHSAFGKNIMPRVSALLDSQQISDITGIESEDTFVRPIYAGNAIMTVQSSDSTKVITVRGTAFPAPEAEGGNAAVEEGVDPKAECPTEWISEDLQKSDRPDLGSADKVVSGGRGLKSKEEFDKLMPPLADALGAAIGASRAAVDSGFADNSLQVGQTGKNVAPQLYLCAGISGAIQHLAGMKDSKVIAAINKDPEAPIFQVADVGLVGDLFEKVPELTEKLKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8T6</accession>
    <name>W6Z8T6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_38160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="KI964015">
        <property type="protein sequence ID" value="EUC43964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689523.1">
        <property type="nucleotide sequence ID" value="XM_007691333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8T6"/>
    <dbReference type="GeneID" id="19123413"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38160"/>
    <dbReference type="eggNOG" id="KOG1282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008523_10_4_1"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000226">
        <property type="entry name" value="Carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF432">
        <property type="entry name" value="Y, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006531590" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC43964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="488" mass="54160" checksum="C500AE6D5B703D05" modified="2014-04-16" version="1">MKLSIASLLAATVPASSFSQVPFQETPDVEGFQLYQSQFSEHHAIRIREQQDDTICNAHGKQYTGWLDVGSKHIFFWYFESQRKPSEDPLLLWLSGGPGASGMLGMMGELGPCMINEHGNGTVFNEYGWSKNANIIFVDQPAGVGFSYVDPGVPLPATSFTAAEDMHHFLQLFTSEVFPSLSGRDFHITGESYAGHYVPALGAQIVSQNLLYPKRPQVNLKSTFTGNAYVSPKDTTFGYWETLCTTNPGVESPVFNQTRCDIMAANLPRCMELTQICYDHPDPAICIAAETVCDEGVIQYYDGESGEGGRNRYDITDGCETKDELCYPEIPRIQKYLNLPSVRQALNVPKAAGNYSVLSLDITWAFALTGDGVQSTQPQVLYLLEHGIDVLFYQGNLDLACNTAGNLQWANTMQWKGQPAFVAQPKRAWKNDGEEVGWFKEVKTKTASGRETTFAFTTVDRAGHLVPFDKPKEALALVDRWLDKRSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8W0</accession>
    <name>W6Z8W0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_25538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687026.1">
        <property type="nucleotide sequence ID" value="XM_007688836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8W0"/>
    <dbReference type="STRING" id="930090.W6Z8W0"/>
    <dbReference type="GeneID" id="19120779"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25538"/>
    <dbReference type="eggNOG" id="KOG3229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069208_0_2_1"/>
    <dbReference type="OrthoDB" id="2329734at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904669">
        <property type="term" value="P:ATP export"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070676">
        <property type="term" value="P:intralumenal vesicle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="227" mass="25868" checksum="408E5D0D24D18094" modified="2014-04-16" version="1">METIKGLLWKPTPEEQKRKCNALVRQNVRKLDRDIQQLKATEQKTKNLIQQSSKRAQRNPAMAKQANQDVRIFARELIRVRKQNNRLMTSKAQLNSVQMQVNEAFSVRKIEGSIKASTGIMKDVNSLVRLPELTGTMRELSSELMKAGIIEEMLDDTLGENEMLEGEADEAEEEVDKVLSEVLKDRLPPSKAQEEELPAAPQPEEEEEEDQAEMLAQMRGRLEALKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8X5</accession>
    <name>W6Z8X5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_2951</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685297.1">
        <property type="nucleotide sequence ID" value="XM_007687107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8X5"/>
    <dbReference type="STRING" id="930090.W6Z8X5"/>
    <dbReference type="GeneID" id="19121518"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2951"/>
    <dbReference type="eggNOG" id="ENOG502SMCQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018404_1_0_1"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="XnlR_reg_dom"/>
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        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
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    <dbReference type="PANTHER" id="PTHR47782:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G12570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
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        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Zn_clus"/>
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        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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        <source>
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        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="665" mass="75388" checksum="C16A184584DD777A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z922</accession>
    <name>W6Z922_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_109492</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily.</text>
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    </dbReference>
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        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
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        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
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    </dbReference>
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            <begin position="46"/>
            <end position="263"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="396" mass="44306" checksum="D156D944AE1F1E2A" modified="2014-04-16" version="1">MERSITIPNSGSTVRVRAIDTTTTMACDASAFVRPVLKGHERLNFKTMCFLIENESKSRRILFDCGGRKDFWNASPHTRNMIGTYVPSLRVEKGVDEILTEVGFDLQTLDAIVWSHWHWDHIGDASKFPPHTDIVVGPGFKSNFLPGYPDDPDAFMLSSDTSGHFVDEITFNNELRIGKFRAHDYFGDGSFYILDVPGHTIGHIGGLARTTPNTFIFMGGDCCHFVGAFRPSAAVPLPDIIPQGQLDSSIPVPCPCSFFTACHPSTTRNEHGVVNDHEVRRSPFYKVTQSETSAYTDAQQSQESIDHLRAFDASPDILICLAHDNTLFDVFPLLATSPERDVNDWKAMGYKERTRWAFLNELPRDGKPGRTPLVSGQWKDGMRISLGDDSYFHEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9M9</accession>
    <name>W6Z9M9_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_87471</name>
    </gene>
    <organism evidence="7 8">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_87471"/>
    <dbReference type="eggNOG" id="ENOG502S41E">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028685_0_0_1"/>
    <dbReference type="OrthoDB" id="20729at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23954">
        <property type="entry name" value="AMO1_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21099">
        <property type="entry name" value="RAD201"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21099:SF2">
        <property type="entry name" value="SI:CH211-113E8.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="179"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
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        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
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        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="236"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="417"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="454"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="501"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="572"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="630" mass="64735" checksum="95D0926C69CD1719" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA94</accession>
    <name>W6ZA94_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Arsenical-resistance protein ACR3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_92113</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686780.1">
        <property type="nucleotide sequence ID" value="XM_007688590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA94"/>
    <dbReference type="GeneID" id="19128012"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92113"/>
    <dbReference type="eggNOG" id="ENOG502QPKH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022869_0_0_1"/>
    <dbReference type="OrthoDB" id="187348at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015104">
        <property type="term" value="F:antimonite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000009">
        <property type="entry name" value="Arsenite transporter, ACR3 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057:SF1">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="ARSENITE EFFLUX TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0059">Arsenical resistance</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC46683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="42108" checksum="C6CBA901CF570093" modified="2014-04-16" version="1">MNTTEQGAYQHGESAGIRDGEDVEKAGGAQAIAGHDGEQRDLPPLKALSFLDRFLVVWIVLAMGIGIALGNTVDSVGPALQKGEFVGVSIPIAIGLLVMMYPILCKVRYETLHLLFNSKELWIQIAVSFVLNWIIAPLFMVGLAWAFLPDRQDLREGLIFVGIARCIAMVLIWTDLAQGDGDYCAVLVAFNSILQIILFAPFAVFYIQVVSHGEKTAVSYQGVAKSVGVFLGIPLGAAVVTRLALRTLLGEARYQRRFIRYIAPFSLIGLIYTIIVLFASQGAHVVRQITDVLRVCAPLLVYFLVIFTSTVWFCWKMGFGYKVSCTQSFTAASNNFELAIAVVVAVYGAGSGQALASTVGPLIEVPVLVLLVYVLKWIRARWQWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAD6</accession>
    <name>W6ZAD6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_25149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686549.1">
        <property type="nucleotide sequence ID" value="XM_007688359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAD6"/>
    <dbReference type="GeneID" id="19120712"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25149"/>
    <dbReference type="eggNOG" id="ENOG502T19T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062848_1_0_1"/>
    <dbReference type="OrthoDB" id="3542212at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42052">
        <property type="entry name" value="ABM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42052:SF1">
        <property type="entry name" value="ABM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="21693" checksum="B6CDA1AE8E620968" modified="2014-04-16" version="1">MPVLEITQLRLRELSADDPALLESLSTVRAELQTGSHFYNCIDDPSVIYILGTWPSLDAHIDFLASPSKDQILGPQEKMLQFCWTVHVELGGVNLLPLDAPILAIERISVSEESTRGFGEAVHRHAQQLQGSHPFKLAHGWRCDAVPNHHEAIIFSGWQTPQAHVAFAAKNNQDGQYKTLQMTCARNLERKVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAE4</accession>
    <name>W6ZAE4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_25241</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the TIM22 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686693.1">
        <property type="nucleotide sequence ID" value="XM_007688503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAE4"/>
    <dbReference type="STRING" id="930090.W6ZAE4"/>
    <dbReference type="GeneID" id="19120729"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25241"/>
    <dbReference type="eggNOG" id="KOG3225">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091077_1_0_1"/>
    <dbReference type="OrthoDB" id="75343at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042721">
        <property type="term" value="C:TIM22 mitochondrial import inner membrane insertion complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039175">
        <property type="entry name" value="TIM22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC46763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="222" mass="22392" checksum="B45587A01F76CFE8" modified="2014-04-16" version="1">MAFPGGPGAMPASMNPTAGMSEQEQQMVKAMQMGMESCLGKTVMAGVMGGGLGAMFGLFMSSMRYDTPMSQPLPMTTPTTPAPSTSAAAAAKPSTVASSASSSAAATLPNPTAAGTVSITDLPLKQQLRAGLRDMYRSSISSGKNFAKVGAIFSGTECAIEGLRAKNDLYNGVAGGCITGGVLARNAGPQAVAVGCAGFAVFSAAIDAYMRMPEDEKSKPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAM9</accession>
    <name>W6ZAM9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hyaluronan/mRNA-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_4141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963960">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAM9"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_4141"/>
    <dbReference type="eggNOG" id="ENOG502SD5D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109896_1_1_1"/>
    <dbReference type="OrthoDB" id="2122308at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="16836" checksum="39C6231099EBC20E" modified="2014-04-16" version="1">MASIGSLQANLLDNGTNKAPWWLTRSHKYTDRDHAGIADGTAEREARLPKYFAKSGHADTDPTKTKKGGSGKGNWGAMGDEVEDIRPNMANARRRSNSSTHNLKDFKTKFETIETEPVFEESIHGPMGEELEKQSTTSTENSIAEEDHGKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB07</accession>
    <name>W6ZB07_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_90856</name>
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    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB07"/>
    <dbReference type="GeneID" id="19127769"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90856"/>
    <dbReference type="eggNOG" id="ENOG502SS3X">
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    </dbReference>
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    <dbReference type="OrthoDB" id="3557394at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
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    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF82">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="63"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="746" mass="84325" checksum="54266148B71CDC98" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBA9</accession>
    <name>W6ZBA9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_40756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964125">
        <property type="protein sequence ID" value="EUC41011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692476.1">
        <property type="nucleotide sequence ID" value="XM_007694286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBA9"/>
    <dbReference type="GeneID" id="19123940"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40756"/>
    <dbReference type="eggNOG" id="KOG4173">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055660_1_0_1"/>
    <dbReference type="OrthoDB" id="18440at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039258">
        <property type="entry name" value="ZNF511"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21354">
        <property type="entry name" value="ZINC FINGER PROTEIN 511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21354:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="290" mass="32314" checksum="FB9682881CF2308B" modified="2014-04-16" version="1">MGVKRSHRDSSSPDAYSTSYSREASVDIKIVQLDADSAVSHEHAVMKCSLPPHDPLTFASIEEHDVHYHQVHMNRCSECHKNFPDQHYLHLHIAEYHDPINAAKRDQGEKTYACLLPECDRLCSTPQKRRLHCIDKHQFPREYDFIVVKDGIDRRSSMLIPPHRRRSSTLSSAGGASGSTGRKRGESSASTVGDSMDVVRDQDEDEKEEHNQGETRRYPTKLHGRGGFGQGQSPGRSIGRGSPQATVSPKRTSPVQTVDPIDSLTSSMSALKFIPHSVRMARGRGRGQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBB9</accession>
    <name>W6ZBB9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_90790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686281.1">
        <property type="nucleotide sequence ID" value="XM_007688091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBB9"/>
    <dbReference type="STRING" id="930090.W6ZBB9"/>
    <dbReference type="GeneID" id="19127753"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90790"/>
    <dbReference type="eggNOG" id="KOG0806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009854_1_1_1"/>
    <dbReference type="OrthoDB" id="201515at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008418">
        <property type="term" value="F:protein-N-terminal asparagine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070773">
        <property type="term" value="F:protein-N-terminal glutamine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07566">
        <property type="entry name" value="ScNTA1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039703">
        <property type="entry name" value="Nta1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11750">
        <property type="entry name" value="PROTEIN N-TERMINAL AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11750:SF26">
        <property type="entry name" value="PROTEIN N-TERMINAL AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="305" mass="33555" checksum="1D6AAB8B90484AF3" modified="2014-04-16" version="1">MKVACLQFAPEVGKLQDNIQRADSILKATQIPADLAWLILPELAFSGYNFHSLEEIKPFLEPTTAGISTQWAQQTAKHYNCHVTVGYPEITVPSRNPADVQTQYNSIVTVSPSGEVINNYRKSFLYYTDETWASEGPGSESHHLSNPASSDSPFFAGELGELGNVTLGICMDINPYKFIAPWTDYEFASKALSFQSPIICVSMAWLCHLSPTELATDPSQPDVATVAYWVERFQPLVEDKGGRPVCVILANRCGMEKGLCYAGSSTVLRIDKGVVSLYNTAGKSEETCLVVDLADRPKFQVRSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBC2</accession>
    <name>W6ZBC2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketoreductase (KR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_3810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686228.1">
        <property type="nucleotide sequence ID" value="XM_007688038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBC2"/>
    <dbReference type="GeneID" id="19123391"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3810"/>
    <dbReference type="eggNOG" id="ENOG502SCIW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_17_1_1"/>
    <dbReference type="OrthoDB" id="5336600at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G03445)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25126" checksum="97B445CADAEE5197" modified="2014-04-16" version="1">MARTLIVFGAGPGIGNNVAAEFASKGINHVILLSRNTERLQNEDAPFVLKGNSSVKVDTLRIDLADLESIPGVLKELDSLTEGEDVEVIFFNAARIKPGEVLGVGVEEIEEDFKTTNLSLYVISQHYIPKLQALAKSNTSLKPALFVTSSHLPWDPIPQLLSLSLVKAAQKNMVDSFRRYFGDSGIHFGLIHVEGTVAPENKVLNPGTIAKRTVSFWESGKGECINIREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBU5</accession>
    <name>W6ZBU5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_106817</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964115">
        <property type="protein sequence ID" value="EUC41186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692289.1">
        <property type="nucleotide sequence ID" value="XM_007694099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBU5"/>
    <dbReference type="STRING" id="930090.W6ZBU5"/>
    <dbReference type="GeneID" id="19118926"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106817"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF177">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="31"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="522" mass="55563" checksum="D9E7B3DB11B3FADA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCC8</accession>
    <name>W6ZCC8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_5664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
        </source>
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    </evidence>
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    </evidence>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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    </dbReference>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
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        </source>
    </evidence>
    <sequence length="476" mass="52199" checksum="CCD0BA851FAAABFE" modified="2014-04-16" version="1">MSKSISILSLLLLSTPASLATSKPNPVQITKDVVIIGGGASGTYAAVRLREDLGKSVIVIEPRPNLGGHTSTYLIPETNTTVDYGVQSYIPYGPASSFFARFNITTEVFSPERLTPLNVDVETGKTLLDYRAPSLNATNEALSRWLTITQKYQQYLEPGYWNFPLPGDIPEDFLIPFEEFAKREGIEAAVPRITTISGVGYGGVRDLLTLTVFQAFGASLTQDFLQSILFRPTNSNNGLLYTRALSLLKSDILLSSTVQSTKRTKNSIQLTVTNSKGSSYLITTNKILFTAPPTLANLSPFQPDKRQKSLFTPWTPSAEFVAIIHAPCLPAKTSISFLPQAIVPTGYLAVKDYPYSLRLDATGPAGTNLFRVVFGANYTLSTPQFQELVRDRVGQLIRAGSVNATTECEVTFRATSDHSRPWWPQDAAKIQSGFVSEVNSLQGYRGMWFAGYAWGAPYSSTVWAVVDTVLERMVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCW6</accession>
    <name>W6ZCW6_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">Carbohydrate-binding module family 18 protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_96097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502S5JG">
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    </dbReference>
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    <dbReference type="OrthoDB" id="5413589at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887380" description="Carbohydrate-binding module family 18 protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="258"/>
        </location>
    </feature>
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        <location>
            <begin position="84"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="25267" checksum="97BDC964D12387B4" modified="2014-04-16" version="1">MRYSFFVLATAGVLASAQSPIALGENCTPGGTPCANGASCYATNSMLQPRCGNFQSSCTSDEQCAFNTCNGGFCNGPKPSSSSAPPSSSAPAPSSTPPTVTSSSTAPGWSPAPSPTIVAPAGSLPLGAECNPYVTPSQCIAGVQCWASNAGLIARCGNFNAACKTDAQCAYNTCNNGLCNGLRASSSGLPVAASSPIPGTLSVKPTPSSGSGGNGTVHPSHTPTPTSSGTPEFTGAASAEKVAGGIFAIVFGAIALGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEH1</accession>
    <name>W6ZEH1_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_87867</name>
    </gene>
    <organism evidence="7 8">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEH1"/>
    <dbReference type="STRING" id="930090.W6ZEH1"/>
    <dbReference type="GeneID" id="19127145"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87867"/>
    <dbReference type="eggNOG" id="ENOG502S6DH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047453_0_0_1"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347">
        <property type="entry name" value="RING/FYVE/PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347:SF1">
        <property type="entry name" value="RING_FYVE_PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="59"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="312" mass="35017" checksum="3E0CA63DE99990E5" modified="2014-04-16" version="1">MSSSSGFQPMPGWYWPDDVPKHEPSQSGTASADTSSRQQHTGETPSGPNSSSQPRSSRRTHWPPRQCRICLETVQPTFNVPSPNLPGFLQSSNVVYEDETGRLIRPCMCKGSSKYVHDACLQAWRHADPSYGRRNYWQCPTCGFRYRLARLGAGRIIGSVSAQVGLTVLILFSIIFVLGFVADPIINLYLDPWSVLLPWTGHSASDYSYYYEDESSTWYEHFAKGFASMGVLGFLKVLLASPLSYFRIGGGTRGRTTGRDRYEQISWIIILVGVATFLTAIYKGVRSWSRRTLERAGERVMDVQGDDEDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEJ8</accession>
    <name>W6ZEJ8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_82513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683358.1">
        <property type="nucleotide sequence ID" value="XM_007685168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEJ8"/>
    <dbReference type="GeneID" id="19126069"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82513"/>
    <dbReference type="eggNOG" id="ENOG502SNMS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054780_0_0_1"/>
    <dbReference type="OrthoDB" id="5397330at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="244" mass="27494" checksum="E93179F0EF19A7E4" modified="2014-04-16" version="1">MPIRNPFRRAGAPDQADDAQRNAPENDFKTTSVSGATPLQLKDPAEYKLSEINDSGVYLPPSPHNEKPTFWHTKSNVSTTSSNHRSLLAENEPFSISRESFDSYRRSFDISARSPITDSVHETYPRQSLDARRSMDTRRSFDARRSRATPRSSMQQGRPSESHDQVPEEGFEDVGLNDEPKPQPKKRGIFSRFGDNNHSNDRTEERPTSSHHFSLTGRKRAESGAGSELKPMPKPAPEMAIESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF09</accession>
    <name>W6ZF09_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_104411</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693201.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19118495"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104411"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023525_0_0_1"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="159"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="13">
        <location>
            <begin position="7"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="338"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC42096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="665" mass="76905" checksum="59FDFDC28CCEC481" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF39</accession>
    <name>W6ZF39_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_33986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684927.1">
        <property type="nucleotide sequence ID" value="XM_007686737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF39"/>
    <dbReference type="GeneID" id="19122454"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33986"/>
    <dbReference type="HOGENOM" id="CLU_054071_0_0_1"/>
    <dbReference type="OrthoDB" id="3763553at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="35852" checksum="AA2DD632E4D6B058" modified="2014-04-16" version="1">MAQNARQKATSNLRRGSRPVFQFTNLPAELQLLILNRCDMISIERLLSVSLYVRSLCIQYPEIVIQGSLSEIPQPFAGFLHVATALHNISVDIYVEVDVAADIVAQSMNAAMQIYIDPQVAVTPVVLSVAEHTRLVCALLIVKIYYQLRSKFVPNGRRSMKDFATAFMQTLAPWQIAQSSSVEGFLDSCQKFLVGLYDEIIDNRYTCCECLFRGWIMYRTVSPDDMMRRHLVWRVGMLFWCQSRLAGWGMVDSSDVVTLGRQTAWRLGYMRRRYPYSLQQGHIEDTTSQQTIEWTRSHEQINFEEFLARQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFH5</accession>
    <name>W6ZFH5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_104074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964069">
        <property type="protein sequence ID" value="EUC42221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691281.1">
        <property type="nucleotide sequence ID" value="XM_007693091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFH5"/>
    <dbReference type="GeneID" id="19118436"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104074"/>
    <dbReference type="HOGENOM" id="CLU_1610466_0_0_1"/>
    <dbReference type="OrthoDB" id="10346888at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="165" mass="17979" checksum="C82F98AFDB8D371C" modified="2014-04-16" version="1">MNIPHLDRITEIGSLQCSMTMNEQASDSLLTRATVRPQFAKTSPSLGSNVTLGIALSTCLLQHPVAWTPCPTETAFPWTTCCPSTDYGLTCREWLDLLTATSVCVAPSFVSKSLPPFLCCASHSRATTGCMSRKTECLMLSYKYPCTLLLPRGKASLHQTPYSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG88</accession>
    <name>W6ZG88_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_86221</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684679.1">
        <property type="nucleotide sequence ID" value="XM_007686489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG88"/>
    <dbReference type="GeneID" id="19126814"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86221"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010365_3_1_1"/>
    <dbReference type="OrthoDB" id="4494341at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000023">
        <property type="entry name" value="Putative ferric-chelate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF24">
        <property type="entry name" value="REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="296"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC48903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="590" mass="66757" checksum="4F6BF93093420D06" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGP3</accession>
    <name>W6ZGP3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Ubiquitin-related modifier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">URM1</name>
        <name evidence="7" type="ORF">COCMIDRAFT_245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the URM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682291.1">
        <property type="nucleotide sequence ID" value="XM_007684101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGP3"/>
    <dbReference type="STRING" id="930090.W6ZGP3"/>
    <dbReference type="GeneID" id="19120601"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_245"/>
    <dbReference type="eggNOG" id="KOG4146">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148208_0_0_1"/>
    <dbReference type="OrthoDB" id="10248987at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01764">
        <property type="entry name" value="Ubl_Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03048">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015221">
        <property type="entry name" value="Urm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14986">
        <property type="entry name" value="RURM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09138">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037379">
        <property type="entry name" value="Ubiquitin-related_modifier_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="modified residue" description="1-thioglycine" evidence="5">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)" evidence="5">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC51022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="107" mass="11868" checksum="7D91B5D1AA917AE0" modified="2014-04-16" version="1">MSSDDTIPIIVEFSGGLEILFANQKKCNLSLPAKDESGKPTDVAFLVRFLCDNVMKDPRKELFVLDGTVRPGILVLINDADWELEGEDQYQVQKGDHVMFVSTLHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGS1</accession>
    <name>W6ZGS1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Brix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_85169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684212.1">
        <property type="nucleotide sequence ID" value="XM_007686022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGS1"/>
    <dbReference type="STRING" id="930090.W6ZGS1"/>
    <dbReference type="GeneID" id="19126615"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85169"/>
    <dbReference type="eggNOG" id="KOG2963">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026936_2_0_1"/>
    <dbReference type="OrthoDB" id="10261452at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045112">
        <property type="entry name" value="PPAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661">
        <property type="entry name" value="PETER PAN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661:SF5">
        <property type="entry name" value="SUPPRESSOR OF SWI4 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="29"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="449" mass="50844" checksum="1122CC6A4A166ED4" modified="2014-04-16" version="1">MARGRGTARKKQSAKDKELAKKPVAGPKSMVIRIGAQEVGKSISDLVNDVRHCLEPDTAIRLKERRANKLKDYLVMCGPLGVSHLLLFSRSESGNTNLRLARTPRGPTLHFRVENYSLCKDIIKAMKRPRSGASDYLVAPLLVMNNFLTSDSDREKLGEKAPPKHLEKLVTDMFQGLFPPIQPHTTPLHSIKRVLLLNREPPSEDTGSVNISLRHYAITTKQVGIPKAIRRLYAAEKLVGSRERKKSALPNLGKLEDVADYMLDPSAAGYTSASDTEQDTDAEVEVTAPVRQKVLSRREKEKLKAGDETSHARARGSKPRVEKRAVKLIELGPRMKLRLTKVEEDVCGGKVLWHEFITKSKAEEQELEKRWQQKNKEKEERRRIQRENIERKRKEKAAKGGTAEGEEEEGEEDEEMEDFEDYDMDDDVWQDAADAGEEGEDDEDEEMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH18</accession>
    <name>W6ZH18_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_28617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964048">
        <property type="protein sequence ID" value="EUC42821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690659.1">
        <property type="nucleotide sequence ID" value="XM_007692469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZH18"/>
    <dbReference type="STRING" id="930090.W6ZH18"/>
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            <end position="29"/>
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            <begin position="83"/>
            <end position="105"/>
        </location>
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        </location>
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    </feature>
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            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
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            <begin position="330"/>
            <end position="345"/>
        </location>
    </feature>
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        </location>
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        </location>
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        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="469" mass="50416" checksum="F113CD879EFD6B83" modified="2014-04-16" version="1">MLQSRKFYLALVGVVAWSSTTVDAVLSILEAASLSSTYSSVASIAATAGTLDLVSLGCVGFYTLHNVGNIRGALEQPGKARTALIAISILLSSVALILSLVLIIVIKSKWEEITAAPPVAPVSNWSSHVSAQIALWIISCASQVILYTSPLWNRKAPKVQTVVTSGPRDSVISELRTHRPSDLFLGKAVEPSSPLAAHHRPEAMGSLPSPTLSIQSSKSLKSFRESLRHVVRPVTSRTTLISQRSFSRDGAPSIYSNRQSSDTISHSDGFDSWDTSGVIIPTRDVVLQQTMSYKGTTLEPIPGSRPNSFGRALDGSFLSELPEEDDEELCPPPRMMPDVSRPPSPAVSEAHIHPLFRSESPSGLPPPAATPGTSIMASPYSNQAIACPPRSFSRMRSSSQLSQTNTINSLHHTRSFTRDRPGSVGSKSRSPSPPSRAITPPIPDFVLNTSPRTSINGSRRVNLQYSPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIG9</accession>
    <name>W6ZIG9_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_101075</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964032">
        <property type="protein sequence ID" value="EUC43341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691954.1"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
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        <location>
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            <end position="155"/>
        </location>
    </feature>
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            <end position="190"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="38"/>
            <end position="497"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="533" mass="58549" checksum="52D4AC3C2D1B3878" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIR1</accession>
    <name>W6ZIR1_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Inositolphosphotransferase Aur1/Ipt1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_90414</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686178.1">
        <property type="nucleotide sequence ID" value="XM_007687988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIR1"/>
    <dbReference type="GeneID" id="19127676"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90414"/>
    <dbReference type="eggNOG" id="ENOG502QTNB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035756_0_0_1"/>
    <dbReference type="OrthoDB" id="2566866at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03386">
        <property type="entry name" value="PAP2_Aur1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052185">
        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310:SF7">
        <property type="entry name" value="PA-PHOSPHATASE RELATED-FAMILY PROTEIN DDB_G0268928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Inositolphosphotransferase Aur1/Ipt1" evidence="7">
        <location>
            <begin position="145"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Inositolphosphotransferase Aur1/Ipt1" evidence="7">
        <location>
            <begin position="225"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="431" mass="48734" checksum="9365038D7DD34304" modified="2014-04-16" version="1">MGAGAFIEPLVVITLLFGGTWVNRNTEYRLLNRPKVYHHSPRSASPESGRSSPLSNTSLLANVDEEPPWQTREIKILGMRKKVVSPNTRRFQDYFLSRLLQKFPFLVEAWYWALIYWVYQVGRGISALYLIDEGTVNVARRHALQLIALEQRLHIFFELDIQAWFLKHPFILHWTNRIYSFIHIPGTILFLVCLYYYTTTRNRIDLPMHNKPIGEASGSPAGAALYAARRRTMATCNLLAFIIFTLWPCMPPRLLSDPDVTGDVGKKARSFGFVDTVHGAEGESSVWTQNKFCNQYAAMPSLHFGYSLLIGLTVMTIPLAPQHARTRSVALTMGLRMRVPSLRRFLCIALGVAYPTTILIAIVATANHFILDAVAGAMVCGIAWVGNGVLLNLLPLEDYFLWCVRIHKPERRSVGWGGEEFKYGSKGVVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ90</accession>
    <name>W6ZJ90_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
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    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053245">
        <property type="entry name" value="MitoProcess-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47563">
        <property type="entry name" value="PROTEIN FMP25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47563:SF1">
        <property type="entry name" value="PROTEIN FMP25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="284"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="348"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="415"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="600" mass="65540" checksum="B4D660E2EFC041B0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMD3</accession>
    <name>W6ZMD3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_86673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684883.1">
        <property type="nucleotide sequence ID" value="XM_007686693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMD3"/>
    <dbReference type="GeneID" id="19126909"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86673"/>
    <dbReference type="eggNOG" id="ENOG502T4M9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1288792_0_0_1"/>
    <dbReference type="OrthoDB" id="3778206at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Apple" evidence="1">
        <location>
            <begin position="153"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="224" mass="24216" checksum="03E1F9D06634E76F" modified="2014-04-16" version="1" fragment="single">QYGILVNATAILATLDPQQNKNCPAQPTCPRWNGCVSTATNGGVFKLNCAIDFNGPIVGIAQANIFVDCADACSRHTYCTAFNMKDNFCYLLGKDFGAPRISLDNVNAGTQSKPATELEPAPGSSVCETDIKCPRDDYCRFKTNGQSYISRCNYDFNGGDIAISQTKSLGECANLCSILNGCVAATWVAAAWDGGMCYLKNDKYKVVYNSNVDSKFLYVLLKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMQ9</accession>
    <name>W6ZMQ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_68</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682057.1">
        <property type="nucleotide sequence ID" value="XM_007683867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMQ9"/>
    <dbReference type="STRING" id="930090.W6ZMQ9"/>
    <dbReference type="GeneID" id="19125086"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_68"/>
    <dbReference type="eggNOG" id="KOG3218">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058320_0_0_1"/>
    <dbReference type="OrthoDB" id="248779at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1340.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.940.20:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1340.10">
        <property type="entry name" value="RNA polymerase, Rpb5, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00025">
        <property type="entry name" value="RNApol_Rpo5_RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014381">
        <property type="entry name" value="Arch_Rpo5/euc_Rpb5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005571">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036710">
        <property type="entry name" value="RNA_pol_Rpb5_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007129">
        <property type="entry name" value="PRK09570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03871">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000747">
        <property type="entry name" value="RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53036">
        <property type="entry name" value="Eukaryotic RPB5 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb5 N-terminal" evidence="7">
        <location>
            <begin position="10"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase subunit H/Rpb5 C-terminal" evidence="6">
        <location>
            <begin position="161"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC51268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="234" mass="26970" checksum="5A270DF28B984676" modified="2014-04-16" version="1">MDGERYSPSLIRLWRVWRTTKEMMNDRGYMVVEDDMNMSLEEFSRRYAREDGEPDRSRLNFSCQPSEEMIAKYTDAPTKKNPNPTPNIGTIWVEFNADENVGMKQLREYMAHLVNGSFHSGIMVTVKAMTGMAIRLLRGATSITDGPKGGVEVFVEQDLLVNITKHELVPKHVLLSDQEKQQLLQRYRLKQTQLPRIQSTDPVAKYLGLRRGAVVKIIRKSETAGRYASYRWVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNT4</accession>
    <name>W6ZNT4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_96101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688251.1">
        <property type="nucleotide sequence ID" value="XM_007690061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNT4"/>
    <dbReference type="STRING" id="930090.W6ZNT4"/>
    <dbReference type="GeneID" id="19128787"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96101"/>
    <dbReference type="HOGENOM" id="CLU_053166_0_0_1"/>
    <dbReference type="OrthoDB" id="10265068at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="38090" checksum="652DD7401F210ADC" modified="2014-04-16" version="1">METAAAMVSFVGLVGTVAQGQKFLYDFTTNMKDCPKDIHDMRAEIESVEDLITQVIRQSKERDVRLRESAVLTRAIGHAQKGVEDLKKELAAYHVIGKRARLIFATKTSQTKKLRASLERTKTIMLDLQRQLHSDVLYDIRDDIRDMSQEVLKSMDNTSRDGGTHDRNFHKITQESKVQEETANNYRDREEASVPPANDPSSEDLTDAEIAAKNLEHVTDLLTETKISSSPNSIPSTPAWSREVSDISVTSSSQETTASSISSWQSLPPSISQNARKANIASKHPLLQFKDNQFQFLVAIIFTQRAKNQHLACQRATEYVVTTDTALLGYMEFLKEEAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNT7</accession>
    <name>W6ZNT7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_96073</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688255.1">
        <property type="nucleotide sequence ID" value="XM_007690065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNT7"/>
    <dbReference type="STRING" id="930090.W6ZNT7"/>
    <dbReference type="GeneID" id="19128779"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96073"/>
    <dbReference type="eggNOG" id="KOG2771">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024580_0_0_1"/>
    <dbReference type="OrthoDB" id="3180714at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF156">
        <property type="entry name" value="INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="3">
        <location>
            <begin position="275"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="424" mass="46862" checksum="8E6B537F47C1DC9E" modified="2014-04-16" version="1">MSTQSALAGRLVPLRTKDEVRASLETHPVYVIEVPAKFANAIKDAVQAALPDFRTSEISHLRRVVQFKYLPPHLQKDFYPPTRLPRGDEDDPALAFLSSSAASSPAQSGSAQTADEALTEHFDLVRYFLLCPTRYLSRADLVAIIRTCPPYDAKTALPRIFHVTVPALAPISADQAAQWSNAYWPISYKNTNPYGPHPSLVQRNQDEIQPGVGAYLGLARVAGEQISHQCLGEEIGVVVVDHTRTKPEIIVVAGDCRWRSFTGTAEPHSGTGNVMAHSVLRAIAMVAKKRLRAAGTDPVYLDRPLFCDNPLTSVEEEYFETDNIHSSGYLCVDLDIYLTHEPCVMCSMAILHSRFRRCIFAKRMPHTGGMTADSPDNSSTAPTGLKNGLFWRPNELNWKFLAWEFKEDGEPAHGATGLKDTLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNY9</accession>
    <name>W6ZNY9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_26517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688180.1">
        <property type="nucleotide sequence ID" value="XM_007689990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNY9"/>
    <dbReference type="GeneID" id="19120943"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26517"/>
    <dbReference type="eggNOG" id="ENOG502SWTK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169378_0_0_1"/>
    <dbReference type="OrthoDB" id="5553410at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="119" mass="13250" checksum="D90321A21BAD0276" modified="2014-04-16" version="1">MSPKSLNNTYHPPPHPYRNKIIVAGIVMALSALPTPSFLLPSSTVLPATVARYLRYTQNFLFYFLYVAHAAETAWFTTKLSKHGVSAGSGAWWKWLGTSFVGGKFCFEYFGKVVGEKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP79</accession>
    <name>W6ZP79_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7492 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_5419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963985">
        <property type="protein sequence ID" value="EUC45416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688075.1">
        <property type="nucleotide sequence ID" value="XM_007689885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZP79"/>
    <dbReference type="GeneID" id="19124611"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5419"/>
    <dbReference type="eggNOG" id="ENOG502SABV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019095_2_0_1"/>
    <dbReference type="OrthoDB" id="64281at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055915">
        <property type="entry name" value="DUF7492"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24320">
        <property type="entry name" value="DUF7492"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887008" description="DUF7492 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7492" evidence="2">
        <location>
            <begin position="18"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="432" mass="46579" checksum="99190F25AE4E56BC" modified="2014-04-16" version="1">MPSVRKIFVAALAAFPLVHSHSWGEQLRNIDDSGKYVGAYGYPRGMVDRGQKGPDGKDTDNSMTWRMPESNTEGKVFIDADQLLCAPTQRQQQQSSEKFPRLKTVPGGFIAIRYQENGHVTLPQNNPEKPEKGGTVYVYGTKEPKTDEKLFDVLQWTQDGQGGDKRGVLLAMNDYDDGRCYLNNETPVAMERKVADPAYMANTPETGPANSVMYCETDVKLPEDVELNKAYTLYWVWQWTSLPGKTPGLDKGKDEYYSTCIDVDVASPKVAMQALDYSDMSEYAMGQQDAVSTAVSDWNARTALYNEMPLKREMGPVTSLLSGGGDSDGGIPSATGTALPSIPTGGPPFSNSTRSAVPTTSAVAIPTFSAPPGAKPTASQSGNDGVLVVTTTVMVTVTAPAATQPIAPVVTTPPASVRSIYHKNGAKFRGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPN5</accession>
    <name>W6ZPN5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8004 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_84337</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683996.1">
        <property type="nucleotide sequence ID" value="XM_007685806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPN5"/>
    <dbReference type="STRING" id="930090.W6ZPN5"/>
    <dbReference type="GeneID" id="19126445"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84337"/>
    <dbReference type="eggNOG" id="ENOG502QUVC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005053_2_1_1"/>
    <dbReference type="OrthoDB" id="5300331at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058317">
        <property type="entry name" value="DUF8004"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601:SF2">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26013">
        <property type="entry name" value="DUF8004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8004" evidence="2">
        <location>
            <begin position="372"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="783"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="797"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="867" mass="94699" checksum="A92E953939F1A882" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZR00</accession>
    <name>W6ZR00_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683558.1">
        <property type="nucleotide sequence ID" value="XM_007685368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZR00"/>
    <dbReference type="GeneID" id="19126237"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83358"/>
    <dbReference type="HOGENOM" id="CLU_2432770_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="91" mass="9643" checksum="5C219F7F569505AC" modified="2014-04-16" version="1" fragment="single">LSPPPPHLVILAAAPLGLLIPPSRRSHPSQPSRSPRPSSLRTQPWGADVCTSRSAALPPATPVLCSHFLLCIQTRGMNDGHSHCTSPINTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSE3</accession>
    <name>W6ZSE3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent DNA helicase CHL1</fullName>
            <ecNumber evidence="24">5.6.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-dependent DNA helicase chl1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="23">Chromosome loss protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="25 26">DNA 5'-3' helicase CHL1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="33" type="ORF">COCMIDRAFT_35728</name>
    </gene>
    <organism evidence="33 34">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="33 34" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="33 34">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="27">ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="28">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 29">Membrane</location>
            <topology evidence="3 29">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 29">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="24"/>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686825.1">
        <property type="nucleotide sequence ID" value="XM_007688635.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZSE3"/>
    <dbReference type="GeneID" id="19122852"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35728"/>
    <dbReference type="eggNOG" id="KOG1133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004691_0_0_1"/>
    <dbReference type="OrthoDB" id="267079at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034085">
        <property type="term" value="P:establishment of sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002774">
        <property type="entry name" value="ATP-dependent DNA helicase chl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000085">
        <property type="entry name" value="MFS peptide transporter Ptr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:005590">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="1108"/>
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        </location>
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        <location>
            <begin position="1190"/>
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            <begin position="1230"/>
            <end position="1250"/>
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        <location>
            <begin position="1270"/>
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        </location>
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        <location>
            <begin position="1323"/>
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        </location>
    </feature>
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        <location>
            <begin position="1355"/>
            <end position="1378"/>
        </location>
    </feature>
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        <location>
            <begin position="1384"/>
            <end position="1405"/>
        </location>
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        <location>
            <begin position="6"/>
            <end position="421"/>
        </location>
    </feature>
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            <begin position="114"/>
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        </location>
    </feature>
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        <location>
            <begin position="1421"/>
            <end position="1449"/>
        </location>
    </feature>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC46616.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="1449" mass="160173" checksum="8288173480AAD60F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSX4</accession>
    <name>W6ZSX4_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_35642</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pleosporales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
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    </reference>
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        <source>
            <dbReference type="EMBL" id="EUC46776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="87" mass="9364" checksum="9A79BA37011F4BE4" modified="2014-04-16" version="1">MGKNGAWLAGLSGLYHVSVLGNNLLPLEGIALARGWWCMHRCISLCPIVMGPQGHSIPLPRAKLTCAAYKVPMCCPRSLKAAKHQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="8">Small-subunit processome Utp12 domain-containing protein</fullName>
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        <name evidence="9" type="ORF">COCMIDRAFT_31777</name>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 10">ATCC 44560</strain>
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    </reference>
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        <subcellularLocation>
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            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
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        <text evidence="5">Belongs to the WD repeat WDR3/UTP12 family.</text>
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    <dbReference type="eggNOG" id="KOG0306">
        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001139">
        <property type="entry name" value="DIP2p Nucleolar protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000157">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000178">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051570">
        <property type="entry name" value="TBC1_cilium_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
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        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN 3 WDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25172">
        <property type="entry name" value="Beta-prop_WDR3_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
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        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="3"/>
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        <property type="match status" value="8"/>
    </dbReference>
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        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
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        </location>
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    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="183"/>
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        </location>
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    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="424"/>
            <end position="464"/>
        </location>
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    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="505"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="604"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="646"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="694"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="8">
        <location>
            <begin position="829"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="963" mass="107427" checksum="225C796FC1683820" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU91</accession>
    <name>W6ZU91_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_90640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963955">
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="95" mass="10097" checksum="4A76980B3B72C205" modified="2014-04-16" version="1" fragment="single">GILIAMQPTPYPASCSPCTGGALDLQCPLKFPLGAQLNCLSPPWSSMAHDVVLNRLCSSSGHLDTCAHTHTHTHLSAASCQVERPCRVRSRSRSG</sequence>
</entry>
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    <accession>W6ZUV9</accession>
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        <recommendedName>
            <fullName evidence="12">NADH-ubiquinone oxidoreductase 24 kDa subunit, mitochondrial</fullName>
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        <name evidence="10" type="ORF">COCMIDRAFT_79313</name>
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            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="9">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC51369.1"/>
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    <dbReference type="eggNOG" id="KOG3196">
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NADH dehydrogenase flavoprotein 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1590:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005725">
        <property type="entry name" value="PRK07539.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371:SF3">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01257">
        <property type="entry name" value="2Fe-2S_thioredx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC51369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="29042" checksum="22A648FF18460B04" modified="2014-04-16" version="1">MASRLVPFACRIAPRASRPFQRAQWRAFSVSRPAWNESGSLNVHRDTPENNPKIPFKFTAQNEELIKEIVSRYPSQYKKAAVMPLLDLGQRQHGFCSISVMNEVARILEMPPMRVYEVATFYTMYNRDPVGKYHVQVCTTTPCMLCDSDAVMKACEDTLGVHHGETTPDGLFTFTEVECLGACANAPMVQINDDYYEDLTYDSTVKLLKALKHSAQATGAQSGELPSPGPLSGRQSCEPAGGLTCLTNEPWGNETLRKDGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZ59</accession>
    <name>W6ZZ59_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_85681</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684437.1">
        <property type="nucleotide sequence ID" value="XM_007686247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZ59"/>
    <dbReference type="STRING" id="930090.W6ZZ59"/>
    <dbReference type="GeneID" id="19126710"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85681"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028814_3_0_1"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002157">
        <property type="entry name" value="Transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000557">
        <property type="entry name" value="zinc finger and SCAN domain-containing protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="209"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="239"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="134"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="453" mass="50609" checksum="DC8B562352B67ED2" modified="2014-04-16" version="1">MAAVVAPHQSGLWQERREPSFQMPNMHSSSMIPQYDTSRAATSAPVSRSFQPTSTQMDMSMPLYPSNTHATTVASYQQPGPFGYEPAPNPYTMQQPSYYQSSIPHPVSYPPSTDVQQLPTVRDGRSLFNPLVKAESTSPLQSNPIYGETSYPSDAKRSNSVPTEGTSVHFSTDVDTLMKAIQAKQTTPSEPVEPKEDATKPSQKPRKRYQCTVPNCNKSFYQKTHLEIHIRAHTGAKPFNCKAPGCGQSFSQLGNLKTHERRHTGERPYSCDICGKTFAQRGNVRAHKIVHQQIKPFTCKLDDCGKQFTQLGNLKSHQNKFHATTLRYLTTKFATISMGDWVSKEDKELWEYFASLYKNSNKGIKGRGKDRRISAMSSASSYPSSYPAMPMASMSRSYGGSFHHSSERSSRSSSMSSDTIQRVDSAYDFNVPMPTSFHHQPQANGYDEMGGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZ86</accession>
    <name>W6ZZ86_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Imidazoleglycerol-phosphate dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_23242</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="4"/>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684397.1">
        <property type="nucleotide sequence ID" value="XM_007686207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZ86"/>
    <dbReference type="STRING" id="930090.W6ZZ86"/>
    <dbReference type="GeneID" id="19120396"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23242"/>
    <dbReference type="eggNOG" id="KOG3143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044308_3_0_1"/>
    <dbReference type="OrthoDB" id="447729at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000005">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000001">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="entry name" value="Imidazole glycerol phosphate dehydratase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133:SF2">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE HIS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC49066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="234" mass="25700" checksum="A07880AEB9FEF57D" modified="2014-04-16" version="1">MPRTCTLNRDTNETKIQVSINLDGGELAPYEHSDFWAALDKANLNGEGEKIDKDHATQKSASQEISVDTGIGFLDHMIHAMAKHAGWSLRIRCKGDLHIDDHHTSEDTFLALGSAFKNALQGSTGLARFGHAYAPLDEALSRAVIDLSNRPYSVIELGLKREKIGDLSCEMIPHCLQSFAQASGTTLHVDCIRGDNDHHRAESAFKALAVAIRHATTVVKQWEGEVRSTKGVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W7A097</accession>
    <name>W7A097_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pathway-specific nitrogen regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_84582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC49446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685804.1"/>
    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="411"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="721" mass="79955" checksum="AE0D90DD96DD37A3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0I8</accession>
    <name>W7A0I8_COCMI</name>
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        <recommendedName>
            <fullName evidence="5 12">Long-chain-alcohol oxidase</fullName>
            <ecNumber evidence="5 12">1.1.3.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_84580</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>a long-chain primary fatty alcohol + O2 = a long-chain fatty aldehyde + H2O2</text>
            <dbReference type="Rhea" id="RHEA:22756"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:77396"/>
            <dbReference type="EC" id="1.1.3.20"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.20" evidence="5 12"/>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684042.1">
        <property type="nucleotide sequence ID" value="XM_007685852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0I8"/>
    <dbReference type="GeneID" id="19126490"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84580"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008878_3_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046577">
        <property type="term" value="F:long-chain-alcohol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
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        <property type="entry name" value="GMC_OxRdtase_N"/>
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        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012400">
        <property type="entry name" value="Long_Oxdase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46056">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46056:SF12">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028937">
        <property type="entry name" value="Lg_Ch_AO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="16">
        <location>
            <begin position="227"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="15">
        <location>
            <begin position="275"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="17">
        <location>
            <begin position="593"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR028937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR028937-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC49546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="746" mass="80959" checksum="90BEF51AB7435AFB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W7A233</accession>
    <name>W7A233_COCMI</name>
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        <recommendedName>
            <fullName evidence="9">Mur ligase central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_1268</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
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    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the folylpolyglutamate synthase family.</text>
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        <property type="protein sequence ID" value="EUC50086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007685183.1"/>
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    <dbReference type="STRING" id="930090.W7A233"/>
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    <dbReference type="eggNOG" id="KOG2525">
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    <dbReference type="OrthoDB" id="5212574at2759"/>
    <dbReference type="UniPathway" id="UPA00850"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF0">
        <property type="entry name" value="DIHYDROFOLATE SYNTHETASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur ligase central" evidence="9">
        <location>
            <begin position="25"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="527"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="493"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="551"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="584" mass="66183" checksum="1683769CC2699651" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2Q2</accession>
    <name>W7A2Q2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin-D1-binding protein 1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_50420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683187.1">
        <property type="nucleotide sequence ID" value="XM_007684997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2Q2"/>
    <dbReference type="STRING" id="930090.W7A2Q2"/>
    <dbReference type="GeneID" id="19124479"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_50420"/>
    <dbReference type="eggNOG" id="ENOG502QZAU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040328_0_0_1"/>
    <dbReference type="OrthoDB" id="4088536at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.10">
        <property type="entry name" value="Talin, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026907">
        <property type="entry name" value="GCIP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049317">
        <property type="entry name" value="GCIP-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492">
        <property type="entry name" value="CYCLIN D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492:SF1">
        <property type="entry name" value="CYCLIN-D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13324">
        <property type="entry name" value="GCIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like N-terminal" evidence="2">
        <location>
            <begin position="59"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="383" mass="41207" checksum="EEEA4621078ABAD6" modified="2014-04-16" version="1" fragment="single">MSKAKDLSTLIEVTKNTQTLLTHYQSSLTPSKTNTATTAIASASAPDPSTEIANPLELLRTSSTLLKSHTTTLSLLLINPPLTASAIVTKIGNVSEGPLTGVVAAASYVPGAGQRGDVGEIMRAEMRAQVKGLLASWSEVLSIVLSIAQKQGAKKGGGVTEAEKQQVLSATGVVWDACDGVEKLCKDGVVGLVVRKAQELRAVLLDAIEELKEWGEDVADDDDDDEAENSDQDDVFATENKLGKDDKELKALLDKSLKKLKMMGILYQALVKRRLKTYPASKAITEKGEGQAEEEEEEEGGEAIQSPSVKLNELMRLLKGIPETVDDIAAAFYDLDADEARETLDRCCGEAKTAVELVRRSWSGQDDEFTAWSEKWVAALDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMW5</accession>
    <name>W6YMW5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_108267</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964149">
        <property type="protein sequence ID" value="EUC40637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692838.1">
        <property type="nucleotide sequence ID" value="XM_007694648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMW5"/>
    <dbReference type="GeneID" id="19119214"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108267"/>
    <dbReference type="HOGENOM" id="CLU_3019761_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="56" mass="6238" checksum="2CAF95BAAEAE0F8B" modified="2014-04-16" version="1" fragment="single">VSTYIQLSIPSWEIRQIKHENCGEAKALVSRLSTTGLRAMGLVDYLMSRADMGRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNR9</accession>
    <name>W6YNR9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_40714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964123">
        <property type="protein sequence ID" value="EUC41037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692438.1">
        <property type="nucleotide sequence ID" value="XM_007694248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNR9"/>
    <dbReference type="GeneID" id="19123933"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40714"/>
    <dbReference type="eggNOG" id="ENOG502STMR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115019_0_2_1"/>
    <dbReference type="OrthoDB" id="2519291at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="29"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="144" mass="16640" checksum="0BD44E21EBB0EFFF" modified="2014-04-16" version="1">MVPKSFQAGYPNTEGFRKVVKATIYIKKKQGMSEEDFIDYYNNKHAQRAVPILQRHGIISYSLTYHLERDRKVIQDIMQGNAKLMDYDAICTFVFPDYLALAKFMYDKEGAALNGDHDNFMDDSQMKMMVGDEYMLVENGQKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPK0</accession>
    <name>W6YPK0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_10335</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964321">
        <property type="protein sequence ID" value="EUC39585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693897.1">
        <property type="nucleotide sequence ID" value="XM_007695707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPK0"/>
    <dbReference type="GeneID" id="19118279"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10335"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF18">
        <property type="entry name" value="NICOTINIC ACID TRANSPORTER TNA1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G03820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="52"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC39585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="508" mass="55837" checksum="2CF2AAB7D6397C3C" modified="2014-04-16" version="1">MTEDKVSVEHKRDEDVAEKISHSSKSGELEAQPTEYDEAEAARVLRKVDIRLVPMLALLYLVAFIDRSNIGNAKIAGMTEDLKMNGQQYNTAVTLFFVPYTLLEVPSNIILKMMRPSYWMAILMGSWGLVMTLMGLTSSYGGLLAGRFFLGVTESGFFPAATFLLTLWYRRFELQRRMAVFYVAASLAGAFSGLLAYGIEKLDGRAGRSGWQWIFLIEGLIPVALALVIWKILPDSPETAKFLTQPERDLLVARLSNDSGSGQGQTTNKDQIGKDQILAGLSDWKIWAATLVFWGNTVGVYGFTATVPSVIKGLGYTSANAQLLTIPIYVFAAILTLIFAWASDLTRMRSPYIIAGYSIAIAGFIAQLAIPKPKYPGITYGFLFPVAGGLYCPFTCLVSWIGNSLAPSSKRAVGMALLISVGNMGGIMGSNIYLAREAPKYRTGFAASLAMCCLAIIMTFVLRWAYSRENARRDALIAAEGEDAIRARYSPEELLLLGDKSPFFRYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ78</accession>
    <name>W6YQ78_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964257">
        <property type="protein sequence ID" value="EUC39770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693712.1">
        <property type="nucleotide sequence ID" value="XM_007695522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ78"/>
    <dbReference type="STRING" id="930090.W6YQ78"/>
    <dbReference type="GeneID" id="19119630"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110645"/>
    <dbReference type="eggNOG" id="KOG4626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001305_4_0_1"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="132" mass="14505" checksum="53DDA975C3EADF84" modified="2014-04-16" version="1" fragment="single">MAVNTMPQDYPDRARCLSNLGNLLGRRFECTGSTDDLNRAVETTDMAVGATPQDHPDRAVRLSNLGAWLGIRFERTGSTDDLNRAVETANMAVSATPQNHPDRAACLNNLGIWLGIRFERTGSMDDLDRAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRJ2</accession>
    <name>W6YRJ2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_104464</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3 8"/>
    <dbReference type="EMBL" id="KI964074">
        <property type="protein sequence ID" value="EUC42072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691419.1">
        <property type="nucleotide sequence ID" value="XM_007693229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRJ2"/>
    <dbReference type="GeneID" id="19118510"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104464"/>
    <dbReference type="eggNOG" id="ENOG502QSWP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025694_1_2_1"/>
    <dbReference type="OrthoDB" id="4187847at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886677" description="Mannan endo-1,6-alpha-mannosidase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC42072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="445" mass="47547" checksum="0D8FEA60495A60D7" modified="2014-04-16" version="1">MFARTAVLSLAFSCLYGNVAAIELDINSRDSIVDAAKSLAGGIVKYYNASVSESGIPGVFPEEYYWWEAGIVLDGLIGYSSLTGDKQYDSLVSEGIQWQRGNNYAFMARNQTASMGNDDHCAWGQAAMSAAEFGFPKPENGTWVDAAISVFDVLTMRWSTESCDGGLSMAIFIFNEGSSYKQMASNGNFFLLASRLARFTGNGTYAEWAEKIFDWTHEKGFITDDYDIYDGADGEKNCTDFNRIQFTYNHGLFTEGAAVLYNITNGKQKWADAVEGFVNSTSRFIENDVLVETACENNGKCSVDQRAFKGVAARSYARAAVAAPALTDPLTLMLEKSAEGAARDCSKSQGGTGDVSCSLSWVNQESMWEYNTASDGNLGEVFGAMEVVQGLLYSQAKIQGSNATGSPVEDGEASKPSGGAAGAAGTMTASITVVLAAAIAAALLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT35</accession>
    <name>W6YT35_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_107995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964142">
        <property type="protein sequence ID" value="EUC40750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692745.1">
        <property type="nucleotide sequence ID" value="XM_007694555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT35"/>
    <dbReference type="GeneID" id="19119161"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107995"/>
    <dbReference type="HOGENOM" id="CLU_2978783_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="58" mass="6312" checksum="BEDE90004DB0D441" modified="2014-04-16" version="1">MSSRQRWLESGAGRERLEAGGHSRAARADLRNAEPGPYCTILTPTPCSYACYTAQVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT90</accession>
    <name>W6YT90_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_64157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC40820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT90"/>
    <dbReference type="GeneID" id="19124955"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_64157"/>
    <dbReference type="HOGENOM" id="CLU_1769071_0_0_1"/>
    <dbReference type="OrthoDB" id="3686806at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="122" mass="13382" checksum="825229D6066F5E57" modified="2014-04-16" version="1" fragment="single">VEAALQTINQAPIESLLVDIRQLCEANSAIAKAICSLSLSLYEETGQFKPQFNGIGDCASAQAKPPPISEINNTQGSDQVTLHQYRSRHGLPEHAVVRLAQYWIKKRLAGTSLLNIVDENRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTU6</accession>
    <name>W6YTU6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964126">
        <property type="protein sequence ID" value="EUC41000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692492.1">
        <property type="nucleotide sequence ID" value="XM_007694302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTU6"/>
    <dbReference type="GeneID" id="19121628"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30166"/>
    <dbReference type="eggNOG" id="ENOG502S8TD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032674_1_1_1"/>
    <dbReference type="OrthoDB" id="5417811at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="442" mass="49332" checksum="95F14F86B9CC70CC" modified="2014-04-16" version="1">MFRSPLFAWSPRPDQDQDIEASPATSSPSRFGAFRSNVRTLVNGSSVYSQSPALTNNNHNETTPKVPFRGFWSRQQSPDPNAQHVSDDEPRDSRDSNAPLSHHTAGSYIGAIQDPQEPTTLYSRHPADVQLPPGHEGPVDPAIQQSTDEASGRRHRRRKHRRRTNRRADRREQWVRRRDERGSTGIYVRGSAARRKMVAVAISGTFLIVILSIYLALALTNKDLGQEIHILFIMVLLTVTIFFCHSLIRLCMLMLNPPTEERQFIPNMLGSEGFQPIIPIRVHLRRDEEAALENDVLENDMDVDDPEKNMPPPPPPAYGLWRSSVRVDPNLIHWQRVDALSERGSAMSSRMPSRVGSVSEQVPPLPTASRAASAVAEGPRPPSYVSEDGISYVVEAAPRSTVTSNRDSHSGYSEIHPAWRPGYAMSEIRGGELPAVANFSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTW2</accession>
    <name>W6YTW2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_30198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964128">
        <property type="protein sequence ID" value="EUC40973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692513.1">
        <property type="nucleotide sequence ID" value="XM_007694323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTW2"/>
    <dbReference type="GeneID" id="19121636"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30198"/>
    <dbReference type="HOGENOM" id="CLU_2263275_0_0_1"/>
    <dbReference type="OrthoDB" id="10420406at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="103" mass="12101" checksum="0EC8A2F4B0CF7415" modified="2014-04-16" version="1">MQRGRWVPVRARCNYNTPHDFFRNANAQHDESQHSQNFLRTEPYSLTVSHQFFFEEGRLPNEQNGRQDPRIGPQKGTGGRYEGAKQQRPGADARREHTRYACR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUJ9</accession>
    <name>W6YUJ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone-lysine N-methyltransferase SET9</fullName>
            <ecNumber evidence="12">2.1.1.372</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Histone-lysine N-methyltransferase set9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">SET domain protein 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_106770</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:64456"/>
            <dbReference type="Rhea" id="RHEA-COMP:15554"/>
            <dbReference type="Rhea" id="RHEA-COMP:15998"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.372"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.1.1.372" evidence="12"/>
    <dbReference type="EMBL" id="KI964114">
        <property type="protein sequence ID" value="EUC41215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692274.1">
        <property type="nucleotide sequence ID" value="XM_007694084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUJ9"/>
    <dbReference type="STRING" id="930090.W6YUJ9"/>
    <dbReference type="GeneID" id="19118918"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106770"/>
    <dbReference type="eggNOG" id="KOG2589">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013724_0_0_1"/>
    <dbReference type="OrthoDB" id="6627536at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140943">
        <property type="term" value="F:histone H4K20 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10524">
        <property type="entry name" value="SET_Suv4-20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1700">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041938">
        <property type="entry name" value="Hist-Lys_N-MTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025783">
        <property type="entry name" value="Set9_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51567">
        <property type="entry name" value="SAM_MT43_SUVAR420_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="16">
        <location>
            <begin position="110"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="248"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="373"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="620"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="308"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="410"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="620"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC41215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="660" mass="75708" checksum="C7F040B870C46391" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUL5</accession>
    <name>W6YUL5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_106705</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964113">
        <property type="protein sequence ID" value="EUC41235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692251.1">
        <property type="nucleotide sequence ID" value="XM_007694061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUL5"/>
    <dbReference type="STRING" id="930090.W6YUL5"/>
    <dbReference type="GeneID" id="19118907"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106705"/>
    <dbReference type="eggNOG" id="KOG0274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_103_2_1"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051075">
        <property type="entry name" value="SCF_subunit_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872">
        <property type="entry name" value="UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872:SF9">
        <property type="entry name" value="UBIQUITIN-BINDING SDF UBIQUITIN LIGASE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="8">
        <location>
            <begin position="158"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="370"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="396"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="437"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="477"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="517"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="557"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Salamov A."/>
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                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVM5</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Grimwood J."/>
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                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="109" mass="11882" checksum="15EE28F4C8F0E857" modified="2014-04-16" version="1" fragment="single">TTKNPRDAVVGCRHRSHCSLPTGILIPLAWIDTPQPTTLVVGSLTASDALTTRAPRLHSARISKLKISRLAICNSICARTPARCIPPPVTYTYLINVDRMVLHANSLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVW8</accession>
    <name>W6YVW8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_105585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964092">
        <property type="protein sequence ID" value="EUC41663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691830.1">
        <property type="nucleotide sequence ID" value="XM_007693640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVW8"/>
    <dbReference type="GeneID" id="19118712"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105585"/>
    <dbReference type="HOGENOM" id="CLU_2947959_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="60" mass="7071" checksum="E65B53C5CA9A3BD4" modified="2014-04-16" version="1" fragment="single">WHFAQCPQHDVRRHFAAAATTGPTQPYEIFLTTTQPVTKHNQEVMFYRAIQLSKFFMCEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW48</accession>
    <name>W6YW48_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964261">
        <property type="protein sequence ID" value="EUC39749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693731.1">
        <property type="nucleotide sequence ID" value="XM_007695541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW48"/>
    <dbReference type="GeneID" id="19119641"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110690"/>
    <dbReference type="HOGENOM" id="CLU_1069591_0_0_1"/>
    <dbReference type="OrthoDB" id="3692783at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="260" mass="29001" checksum="FF1DC840B07D6E73" modified="2014-04-16" version="1">MSPQGPSSSPSESADIHQSKGVKGASNPLYTVTPSIPLQNLAEIIKDAVVQALATQRKELTTAMTNQCYKPMHSLTAELKSLKKFIEKQDKQAPIRSLDAVLLKVVLKLTTADTEKMSKTIPAERLQMVQSLGKPYDRATSIRVYSNINELAIFTDSLPVHEELKKPESVAAMTRALGLEPKSSIKLDTYWVILHEYNLQNDYLRDCKGHLEEMKSQTGLDIREVKYVAQKLLWGFRTPSEAVKACQKPLYFAGDHALAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWX7</accession>
    <name>W6YWX7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Prion-inhibition and propagation HeLo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_67068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964207">
        <property type="protein sequence ID" value="EUC40024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693456.1">
        <property type="nucleotide sequence ID" value="XM_007695266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWX7"/>
    <dbReference type="GeneID" id="19125049"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_67068"/>
    <dbReference type="eggNOG" id="ENOG502S8GV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058675_0_0_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542">
        <property type="entry name" value="HELO DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37542:SF3">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prion-inhibition and propagation HeLo" evidence="1">
        <location>
            <begin position="6"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="227" mass="25447" checksum="A12BBAA49D759293" modified="2014-04-16" version="1" fragment="single">MAETAGLLIGAVSLTTIFTTCVDCFEYVQLGRNFGKDYQRALLKLDIAKLRLSRWADVVDESHNQCRVSVGTSAEAEKVKEILGEIVTCFADAEKVSQRFKTKSGSTELQVYDVNTDLEPSLRTMHDKMRDLALKRQHRSTVRQKTAWALYEKKHFDRLISDIVELVDSLVQLFPATQQRQSELVVEEVQEIESHPALPEIEAAAVDVDSLLLSSVQRALAAQGSHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXN9</accession>
    <name>W6YXN9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_8072</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964065">
        <property type="protein sequence ID" value="EUC42320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691145.1">
        <property type="nucleotide sequence ID" value="XM_007692955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXN9"/>
    <dbReference type="GeneID" id="19125716"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8072"/>
    <dbReference type="eggNOG" id="ENOG502S6CG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029871_3_2_1"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF1">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889338" description="Heme haloperoxidase family profile domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="81"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="430" mass="45900" checksum="46806FFCBB0C8ACF" modified="2014-04-16" version="1">MYFLNARIALLAVATAPLTAAWPTAILDAAEHDPELLKRAEQEVARAMQARQNSASAATTIFEPVPIFDAKAQYIDVSAGSGHEYVPPGPDDLRGPCPGLNALANHNFLPHNGYATVTQYVEATTKVVGMGPTLALLLSAVGGALSGDILNWSIGGKPSLAQAGLTGILGNGLTGSHNKYETDASPTRGDLYQTGNNFNTVPAQFQQLIDASPGGVVTLESLTEFRSARVDAQRKSNPYYFSGPFAGVLVQPAAYTFIFRFMANHSAENPEGVLPYHVLQSWFGIQGTSGKYTAVQGGERIPNNWYRRPIAYPYDTPYFLADTLNAAALYPKFLEIGGNTGQPDSFVGVDVASLTGGIFSSANLLKGNNLACFVYQVSAIAKPDILLGLLTTLLDVVNNAVAALSCPQLKNFDQSVLKQFPGYNRQNVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXW9</accession>
    <name>W6YXW9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_8007</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964062">
        <property type="protein sequence ID" value="EUC42420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691056.1">
        <property type="nucleotide sequence ID" value="XM_007692866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXW9"/>
    <dbReference type="GeneID" id="19125594"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8007"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025001_1_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="519"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="572" mass="64791" checksum="2C57CEA7C3BBECB0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXZ1</accession>
    <name>W6YXZ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_6445</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964009">
        <property type="protein sequence ID" value="EUC44202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689261.1">
        <property type="nucleotide sequence ID" value="XM_007691071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXZ1"/>
    <dbReference type="STRING" id="930090.W6YXZ1"/>
    <dbReference type="GeneID" id="19124962"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6445"/>
    <dbReference type="eggNOG" id="KOG2103">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005034_0_1_1"/>
    <dbReference type="OrthoDB" id="28092at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058545">
        <property type="entry name" value="Beta-prop_EMC1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026895">
        <property type="entry name" value="EMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011678">
        <property type="entry name" value="EMC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25293">
        <property type="entry name" value="Beta-prop_EMC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07774">
        <property type="entry name" value="EMC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886231" description="ER membrane protein complex subunit 1" evidence="12">
        <location>
            <begin position="19"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="906"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="domain" description="EMC1 first beta-propeller" evidence="14">
        <location>
            <begin position="18"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="13">
        <location>
            <begin position="710"/>
            <end position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC44202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="937" mass="101711" checksum="1F0DE3280EFD3540" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY56</accession>
    <name>W6YY56_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964059">
        <property type="protein sequence ID" value="EUC42508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY56"/>
    <dbReference type="GeneID" id="19121399"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28890"/>
    <dbReference type="HOGENOM" id="CLU_1371969_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="199" mass="21886" checksum="E360F525CC3867E3" modified="2014-04-16" version="1">MAAVSRVSHGRAPSSGTRPLTRVIRTSSSNGHGTRDHRVDQNRDRRPCILNCYTLTATGHGSQSIAGVLWRWEVRIRTGCKSGEYHAALWSSKKNPPRPIAPATSVINIHHFDTRGDTSMSEHSTALPACPKRQHPTHASVTAVIALLPPHERSCLPFVRSHHDAYEPHSSARRANTPTLGLHAESTSRPCCRWQMGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZQ4</accession>
    <name>W6YZQ4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_7436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964040">
        <property type="protein sequence ID" value="EUC43090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690384.1">
        <property type="nucleotide sequence ID" value="XM_007692194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZQ4"/>
    <dbReference type="STRING" id="930090.W6YZQ4"/>
    <dbReference type="GeneID" id="19125286"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7436"/>
    <dbReference type="eggNOG" id="ENOG502SFSW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1215432_0_0_1"/>
    <dbReference type="OrthoDB" id="5390017at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="228" mass="25048" checksum="F8B0ADBE29CF7EBA" modified="2014-04-16" version="1">MDVALSRKRSRLALDDDDDLPPKREPSPAPSPFGDTLKKSKTQCELEELEIIRPEDAWTVDVDAILASNVLAAPPDSKLQAHNNWARYQRGQSITVLCVQGNVQIHFELLCSALPDLYKLSPSLQALVLCHDPSTHRLSPSAPFSLPLVQAATTSNNHFVRLGLLHPLGGGKFPLDALVVLDRNAKRRLVLPFGWGAGKHAGTPAGRSIQMTLMRLLRSCVEQLQQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z009</accession>
    <name>W6Z009_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_5809</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688514.1">
        <property type="nucleotide sequence ID" value="XM_007690324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z009"/>
    <dbReference type="GeneID" id="19124745"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5809"/>
    <dbReference type="eggNOG" id="KOG4510">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032828_4_3_1"/>
    <dbReference type="OrthoDB" id="306876at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="112"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="302"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="482" mass="53203" checksum="FD44624A6859D2BB" modified="2014-04-16" version="1">MDQPTPPKFTANNDKTAQQPQEPRLVAEPRLKSGDKAESTLTVNRGAIRVPSPDPSLVSIDDFNNVRIGRIPDRSISIPFYHGTQVSRSPSPPRTFKGKIQASWTANKGLALVLISQLFGTLMNVTTRMLEMEGNNGNGYHPFQILFARMSITVLCSSLYMWYKKTEHFLFGMKEVRPLLMARGLTGFFGVFGMYYSLMYLPLADATVITFLAPSLACWACSYLIDEPFTRMEQIAAYVSLFGVVLIARPVSLFAALSHSPEMVSPVSANPDSLLTANTTTAPPDRLAADYDSVTPKQRAIAVGVAMLGVFGAAGAYTTIRWIGKRAHPLITVNYFGVWCTIISIVAMLTVPGVGFLLPSNLADWCYLIFLGICGFIMQFLLAAGLQYEKSSRATNMVYMQMLFALSFDKLVWGTTPGALSIIGSSLILGSALYVAMNKEHSTKVAPRERGNVEEEMGLMAPEYDNEQREHEETHVQMRSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z201</accession>
    <name>W6Z201_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_94513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687677.1">
        <property type="nucleotide sequence ID" value="XM_007689487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z201"/>
    <dbReference type="GeneID" id="19128463"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94513"/>
    <dbReference type="HOGENOM" id="CLU_2967138_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="59" mass="6116" checksum="87DFAEB262E8C516" modified="2014-04-16" version="1" fragment="single">MSTTLVTSRTRQSTTTPTSTRRSFATSSTISTPRPGPSTSISTTSTTFTTPTPSSSPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2L7</accession>
    <name>W6Z2L7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Urea active transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_38168</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Pleosporales</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
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                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
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                <person name="Han J."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689106.1">
        <property type="nucleotide sequence ID" value="XM_007690916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3T9"/>
    <dbReference type="STRING" id="930090.W6Z3T9"/>
    <dbReference type="GeneID" id="19129235"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98329"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_0_0_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF32">
        <property type="entry name" value="FAD-LINKED OXIDOREDUCTASE AFOF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886600" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="57"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="486" mass="52180" checksum="D95943854BC128AC" modified="2014-04-16" version="1">MAVHLVFGLLCSVNLAWAVTPGQIQNYLKTQLSPSSEVVLSSSQAYTTEIKQRWNAYDAPSFVVGVKPATANDVATIVHYASSNSIPFMGTGGGHGYTITTSALKNGINIDLGGFKGVSINSAASTMTIGGAVTFGEVLNPVYQAGKEIQTGSCSCVGMVGATIGGGIGVYQGLHGLVIDALQSVTIVTGKGDIVNASLSENSDLFWGIRGAGQNFGLITSATYKLHDQTNRGQALNGDFLFPVSANATIFNVLKSFTRNQPDALALTSAIQYSPTLNKVVIMVNAVYVGAENDGKKILQPLLSVKALQSNVTMIPYNRLILENRFGVDPLGCISGLPQASYGMNLYQYDVATYQKTLAAYIDFYAATNLTTSYMVTEIFPTRVSLSTPDKATAYPYRATMAYLFMSFSGFTTDTQTSAIAKFAKEIRGNFAKLNGAKGLEVYVNYAHGDEGRNAWYTAAKLPQLEQLKRKWDPQNLFNFTNGFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z469</accession>
    <name>W6Z469_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_25393</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686882.1">
        <property type="nucleotide sequence ID" value="XM_007688692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z469"/>
    <dbReference type="GeneID" id="19120754"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25393"/>
    <dbReference type="eggNOG" id="ENOG502QPR4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024588_2_0_1"/>
    <dbReference type="OrthoDB" id="4676at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03884">
        <property type="entry name" value="M20_bAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494:SF5">
        <property type="entry name" value="ALLANTOATE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="ALLANTOATE DEIMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="281"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="506" mass="56020" checksum="9693A46E1F0AF053" modified="2014-04-16" version="1">MASLANRTPVALRNACRRYPALSTRPSVRARVGHEHARNFTNSPRWQIRTKEMNDDMMKELKVNQARLMDDIHHSCQWGIGERWGDKPTETGMSRLALSDADKSARDWFVQTTKELGCEVTIDNMGNTFAVRPGLRNDKPPTFVGSHLDTQPTGGRYDGILGVTAGIEMLRVLAENWTETEYPVGVVNWTNEEGARFPMSMVSSGVWAGSIPLETAHNLREVHPGTSTMKSELERIGYLGDVPASYEATPMAAHFELHIEQGPLLEMANKKIGIVASVQAYKWFTIKVKGRDTHTGTTDLKSRADALLTTSKMILHSHRLATANNALASTGILNLKPGSTNTVPGEVTFSLDIRAPKDETVEKMKEMILRDFPKIAAGEDVEGSNYGCTSGLPLTVDIVEDFDSPATKFHADCIASVRQSANSIVGPHLSMEMTSGAGHDSVYASKRCPTSMIFVPCREGVSHNPREFCKEEDCALGAQVLLQSVIRFDRMRDERRVSWKQEPYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5D1</accession>
    <name>W6Z5D1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 39 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_102625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964049">
        <property type="protein sequence ID" value="EUC42774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690699.1">
        <property type="nucleotide sequence ID" value="XM_007692509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5D1"/>
    <dbReference type="GeneID" id="19118120"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102625"/>
    <dbReference type="eggNOG" id="ENOG502RGI5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023231_1_0_1"/>
    <dbReference type="OrthoDB" id="3445803at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889543" evidence="1">
        <location>
            <begin position="20"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="459" mass="50092" checksum="AC85F58D82BCE055" modified="2014-04-16" version="1">MRSSAVASILLSSLTFLEAANIRRVAKGVATVDLSKTSGQAKFLASGWIYGFPDNGTEADTSIPANYITDVKFGSSRAGGAQTSSRGWVDGYDSYLPRFESTLSNYRTTRKYNGEFIVLVHDLWGADGSSIPLFPGDNGNWTETDAFLTQLVKDIKANNMLDGLILDLWNEPDIDIFWGRTWSQYLEYYVHAHNFFRQLTNSPRLRKNLASTTLSGPSMASSPRTNSENWQTWLSTIASKNATPDIYSWHQIGTGSRQPDATIPDFATLRSSQNLPERPIDINEYAAKEEQTPGCSVYYIAQLERHNLRGLRANWGSGTGLHDSLANLVFNTSSAVYRPNGEWQLYKYYAGMTGERLATTAAADSQFDVFATRSADGLVKVIAGTRIVEGQYDIQISGLEGASVSVATYRFDWAGPGGEIEAPVALGTSTVNISSGVITISVDPATNATAYAYEISGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5P9</accession>
    <name>W6Z5P9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Autophagy-related protein 28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_91215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686438.1">
        <property type="nucleotide sequence ID" value="XM_007688248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5P9"/>
    <dbReference type="GeneID" id="19127835"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91215"/>
    <dbReference type="eggNOG" id="ENOG502SANW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015530_0_0_1"/>
    <dbReference type="OrthoDB" id="5342758at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="418"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="183"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="54516" checksum="CFABEC18C33648FE" modified="2014-04-16" version="1">MSILNSVLGSLSPPSGFRKSFEDPHAREHELPSYNSSSPPRIPPPVTSSVLWTAPKANIPIQPRIPDDLLALQRRARHLEQQLQELLDAQADGLMAGLGAGSNIPDDLVSNGSTTPTVSSVRSSDKSADNGETLSKPRRKKVGLQAARHGISRRMKQLASIKAEELDLLDEDLRKVQSTVEKTDAWSQKRTRLEKKIREIEGQDAGAKTRSLQTEASKLEQEIRQKEEELWALKRRHRRILDELADTENSVEAKIASYKTSLSLLDREVSSFLARPVDPNHVPVSSSPYPTLPAKRRTLEMAREYWQDEYTRLAEKCEEIDTDRGALDEGALLWSDVMKRVADYETSLQNYMQQAGRKNPPEPSKLLEQMDKTISYLEEKLELASSRSWNLLVCAIGAELEAFTQGKDMLEEALGLKRKGKEKATEPLLDQDGFQAEQSEDMTVSAIRITQSPKPPTPPKQQYFDSEDDDPDPELLISHQDIDTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z652</accession>
    <name>W6Z652_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">25S rRNA adenine-N(1) methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_90655</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BMT2 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686268.1">
        <property type="nucleotide sequence ID" value="XM_007688078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z652"/>
    <dbReference type="STRING" id="930090.W6Z652"/>
    <dbReference type="GeneID" id="19127728"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90655"/>
    <dbReference type="eggNOG" id="ENOG502R82D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041583_1_0_1"/>
    <dbReference type="OrthoDB" id="5954793at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016433">
        <property type="term" value="F:rRNA (adenine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03044">
        <property type="entry name" value="BMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021867">
        <property type="entry name" value="Bmt2/SAMTOR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21008:SF1">
        <property type="entry name" value="25S RRNA (ADENINE(2142)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21008">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11968">
        <property type="entry name" value="Bmt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC47212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="287" mass="32311" checksum="6CB8F5F926FA12E3" modified="2014-04-16" version="1">MAVKKRQKTLSHGRPPISKPKERMTSERSRTIIRTHHRLQKEHAAALRKGDLSSAEEIARAIEKNGGIKTYQAASKQGQAKDRGGDSSKVLVEWLQKSHVLGAKERGHIMPKLRCLEIGALSTKNEISKYSSVIDMTRIDLNSQGQGIEKQDFMQRPLPTADGERFDIISLSLVLNYVPDATGRGEMLKRITKFMRRSTARVDDSLLALPALFFVLPLPCVDNSRYLDEDLLLQIMGRLGFNMTFSKKTSKLCYYMFILTGEPTKATTEKKKIRDGPGMNNFCVVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z680</accession>
    <name>W6Z680_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_90681</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686283.1">
        <property type="nucleotide sequence ID" value="XM_007688093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z680"/>
    <dbReference type="STRING" id="930090.W6Z680"/>
    <dbReference type="GeneID" id="19127734"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90681"/>
    <dbReference type="eggNOG" id="KOG1617">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051314_0_0_1"/>
    <dbReference type="OrthoDB" id="10020554at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043337">
        <property type="term" value="F:cardiolipin synthase (CMP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000017">
        <property type="entry name" value="Phosphatidyl synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC47247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="402" mass="43944" checksum="807D746003A3C162" modified="2014-04-16" version="1">MIPLSTARAISPCHIPAALLRTAIGLGSIFRPAHGRPSLYLAASRASGTWTHNDVKKYQHRRVVRGPAYGQCGQRHVGLFSTSTTRRLGIEDKAKGPSASRNNAERHVPSITASTKLASTIKSTLKLDKPRHEQIYNLPNMLTFSRLIATPAVGYLIIHDQHLYAFSLFVYAAFSDLLDGWIARRWNLQTVVGSVVDPMADKFLMTTLVTCLAVNGSLPMPLACLILGRDVSLAISALYYRYASLPAPKTMARYWDFSLPSAEVHPTTVSKFNTFLQLSLLGTLLCTNLLHDPSATSSAAGGLLLSIQDVLGGEQGVKTLVQGVSAIVASTTIYSGLEYTWSKKAVIILGGDEALKRKQGFRGRMIMAAGFGSFISLAAYFWVNRRAEEEIKEKARKKLVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6Q8</accession>
    <name>W6Z6Q8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fructose-2,6-bisphosphate 2-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_7323</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.46" evidence="2"/>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690245.1">
        <property type="nucleotide sequence ID" value="XM_007692055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6Q8"/>
    <dbReference type="STRING" id="930090.W6Z6Q8"/>
    <dbReference type="GeneID" id="19125249"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7323"/>
    <dbReference type="eggNOG" id="KOG0234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006383_1_0_1"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000005">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="8">
        <location>
            <begin position="33"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="253"/>
            <end position="260"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="460" mass="52267" checksum="A13B501524E1C6DD" modified="2014-04-16" version="1">MTDTNGTYAPNMRAVPAGDFVRPSRKTNGAGIQAEDTRICVVMVGLPARGKSLIAQKVVRYLHWLSIKSKTFNVGQYRRTATPNPSAEFFDTSNPEGERLRKAAAEAAVNDMCKWFSEGKGLVAILDATNSTKSRRRWIQERCTADNIETLFVESKCDDEELIMSNILEVKTTSPDYVGQDPEAAAADFRNRIRNYEKVYQTIDEDERDLTYVKLINVGKQVIINQIQDYLQSRVVYYLMNLHIKPRSIWLSRHGESEYNLTGQIGGDANLSARGDAYAHALPGLVAKSVGDGRKLTVWTSTLKRTIQTARFLPFEKLEWKALDELDSGVCDGLTYAQIEQKYPEDFKQRDEDKYNYRYLGGESYRDVVIRLEPIIMELERSENILIVTHQAILRCIYAYFMNVPQEQSPWMEVPLHTLIKLTPKAYSTQEERLKADIPAVSTWRGKGTKAEHQPANGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6V7</accession>
    <name>W6Z6V7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_94820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687796.1">
        <property type="nucleotide sequence ID" value="XM_007689606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6V7"/>
    <dbReference type="STRING" id="930090.W6Z6V7"/>
    <dbReference type="GeneID" id="19128521"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94820"/>
    <dbReference type="eggNOG" id="ENOG502SH5D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041307_4_1_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="493" mass="55892" checksum="9CE64A1505518556" modified="2014-04-16" version="1">MASFRSLTADRRPFDEFKTKSRNSAESRKEKSYGVVNLHVFEWLDSAVQGKEIGGIQSIEALESQSKGAVRVIFAPPDKPTGNYGESLLEFLEEWRIPSAFVDEGLQGVSQSFAAREDVDGTTFVWFHFLCKTLAIIDKKIVHLGGEDEDASGLKMRQTAQSQPQANFSWIKPGFVLKIREQNATTPKPARTFSSNSDDTLSSTTAPPVVELFCFGVPASFQNRFRALVNMAKCEDLIRDPYTLLEVAFEEMYKVLDWTGWNLGDIFGEMETQALEMARNPGKATKDSLKDHFTGLHNLAKHTIYLRENCEAALATLQGLYDHHESVIGKTPSFHQKFTRQALEYRRTLFESTQRRLTSLDARISNIIQLSFNVVTQGDSKVMQSENQSMKTIAVTTLLFMPLGTVASIFGSQFMQLQEEYPHHITVSQDFWLMWVIAVPLTIIVVIVWRVWYVDAREHLVDGIEKEEGKGYLGWRSLFRRVRRKVAPAKIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6W8</accession>
    <name>W6Z6W8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 105 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_95274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6W8"/>
    <dbReference type="STRING" id="930090.W6Z6W8"/>
    <dbReference type="GeneID" id="19128621"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95274"/>
    <dbReference type="eggNOG" id="ENOG502QV67">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_514823_0_0_1"/>
    <dbReference type="OrthoDB" id="540611at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
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        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052043">
        <property type="entry name" value="PolySaccharide_Degr_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886:SF9">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886696" evidence="3">
        <location>
            <begin position="18"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="530" mass="57447" checksum="BA1562C63D7D16A2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z753</accession>
    <name>W6Z753_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribonuclease Z</fullName>
            <ecNumber evidence="4">3.1.26.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_94911</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase Z family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="4"/>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689631.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z753"/>
    <dbReference type="GeneID" id="19128539"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94911"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2121">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006220_0_0_1"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990180">
        <property type="term" value="P:mitochondrial tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07718">
        <property type="entry name" value="RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047151">
        <property type="entry name" value="RNZ2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027794">
        <property type="entry name" value="tRNase_Z_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553:SF49">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13691">
        <property type="entry name" value="Lactamase_B_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNase Z endonuclease" evidence="13">
        <location>
            <begin position="310"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1148"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1266"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1168"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1205"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1300"/>
            <end position="1316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC45623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1316" mass="144693" checksum="CA24BF0B2D3457C1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z776</accession>
    <name>W6Z776_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RCC1/BLIP-II protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_69776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964030">
        <property type="protein sequence ID" value="EUC43414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690094.1">
        <property type="nucleotide sequence ID" value="XM_007691904.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z776"/>
    <dbReference type="STRING" id="930090.W6Z776"/>
    <dbReference type="GeneID" id="19125141"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_69776"/>
    <dbReference type="eggNOG" id="KOG1426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100842_0_0_1"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051709">
        <property type="entry name" value="Ub-ligase/GTPase-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622:SF60">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886541" description="RCC1/BLIP-II protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="25257" checksum="B53B4E23CF504839" modified="2014-04-16" version="1" fragment="single">AHLRVWLAAGTFALATASASAVPVKRAPYDSHGAPQVVSNATTTSVLGCSGGAVWTSSSGARYQACVGRPFSTDGVLEFRPIPYLEQTCVEQVASGGYLSAVLSTDGELFVWGQACPGSTGEMDVLSGNADGHVPSTGIAAEEDDSDEFVKCLQVRTNGQEARVYQVAIGHGHVLVAAEPGNGSPAKERVVFGAGDNSMGQLGLEERRFYSAFHEVQSLRGKRVAQLYAAGWSSFVVTLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z964</accession>
    <name>W6Z964_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein/NADH dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_87971</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685264.1">
        <property type="nucleotide sequence ID" value="XM_007687074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z964"/>
    <dbReference type="STRING" id="930090.W6Z964"/>
    <dbReference type="GeneID" id="19127171"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87971"/>
    <dbReference type="eggNOG" id="ENOG502SDFJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094283_0_0_1"/>
    <dbReference type="OrthoDB" id="1696305at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040049">
        <property type="entry name" value="Ribosomal_mS25/mL61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13274">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13274:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="6">
        <location>
            <begin position="40"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="206" mass="23290" checksum="2BFBF893463B4809" modified="2014-04-16" version="1">MVHILSRMRKLRELLWIRCGPGALILPKEVSKISMEFNTKIYGGHRGARKFWREMLPRIKYRNPSVPIQISRHNDADGPALLHIYTASKTQPAAGTTNAPVAQQSDSTPPSGTPNARNTLVPDTSKPTYTINIRDQMESEILEALVAQTGAQEIKPTEQELAEMREIAEFKERSEADRIQVRERLLKERREAELLKLARGEVPATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9F5</accession>
    <name>W6Z9F5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_2798</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685113.1">
        <property type="nucleotide sequence ID" value="XM_007686923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9F5"/>
    <dbReference type="STRING" id="930090.W6Z9F5"/>
    <dbReference type="GeneID" id="19121221"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2798"/>
    <dbReference type="eggNOG" id="KOG3419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100590_2_2_1"/>
    <dbReference type="OrthoDB" id="407221at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1320.10:FF:000012">
        <property type="entry name" value="37S ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_bS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_bS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_bS16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_bS16_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919:SF20">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="Ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC48357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13736" checksum="955D930709C14131" modified="2014-04-16" version="1">MVLRIRLARFGKKHAPFYNIVVAHARTARNSRPLEVLGTYDPKPQPPRPGDTYGRPWKDIKLDIARARYWVGVGAQPSDTAWRILSMVGILEPQYRVGQVQGQVIKADSAFKSLVPEKKAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9P4</accession>
    <name>W6Z9P4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HAD-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
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        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF4">
        <property type="entry name" value="ACID DEHALOGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="26842" checksum="F830955A21B7A70B" modified="2014-04-16" version="1">MTRSASFDVIGTCFGFSAPIQAIHSRLGPKLKTADVDPKTLFFSWFYAAQRDFTYVSMTGSYVPIAQVLKSTFRRACAVVDLPTDAVTDEDLEEIMKAFRSMGPREGLKACFDGLREAGWEVYGVTNGGSETSLNYYHSAGIELDADHLLSCDAIQVAKPDVRVYENANQYISKRLQGKEEGERWFVAAHAWDLIAARKAGFKTAYLTLEEHDPCTDVFGEFDLYASSMVELLRKLEELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9Y2</accession>
    <name>W6Z9Y2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_9631</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964159">
        <property type="protein sequence ID" value="EUC40516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9Y2"/>
    <dbReference type="STRING" id="930090.W6Z9Y2"/>
    <dbReference type="GeneID" id="19128828"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9631"/>
    <dbReference type="eggNOG" id="KOG0299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014017_1_0_1"/>
    <dbReference type="OrthoDB" id="189968at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rrp9-like"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="214"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="256"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="359"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="596" mass="65367" checksum="9C39E04FF51C23F0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB56</accession>
    <name>W6ZB56_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trm112p-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_97501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRM112 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690612.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZB56"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_97501"/>
    <dbReference type="eggNOG" id="KOG1088">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2187549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035657">
        <property type="term" value="C:eRF1 methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043528">
        <property type="term" value="C:tRNA (m2G10) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160102">
        <property type="term" value="F:tRNA (guanine(10)-N2)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="16666" checksum="D6244C3765EE7084" modified="2014-04-16" version="1">MKLLTLNFLTCAIKACKTNPASFPLHPRDAELEIVEADVNLAFLKNILPRILWNELRVVCSELGLPELPPTAPTPADLVEPSSSSAAALDTTDATPAADAQEEQEEEPSQTAKDLHRILLETCIKEGKLVCGACQHEYAVKEGVANFLLPGHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB94</accession>
    <name>W6ZB94_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_24834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686235.1">
        <property type="nucleotide sequence ID" value="XM_007688045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB94"/>
    <dbReference type="STRING" id="930090.W6ZB94"/>
    <dbReference type="GeneID" id="19120646"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24834"/>
    <dbReference type="eggNOG" id="KOG3489">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037962_1_0_1"/>
    <dbReference type="OrthoDB" id="5337308at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889663" evidence="1">
        <location>
            <begin position="19"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="400" mass="43985" checksum="F4B6F83886BFDBA9" modified="2014-04-16" version="1">MRLLLLIACATCATFVHGLVVPDVPSELATGTTNSTFPSEHPLEEWSEPVKAAADDPWTLSVARGAKLLQGMRSNDADAASLYGLATTAESPFNGNLIDKLREWGYNDNNDALAKQADPECNFDSRDGHMLKKAFTDLGIGISSKGKGGPNQCFAIEHTNGPAVKLGDNGKMPEKADQRYEVCGKEYRVTNAEHTIGVNTEAGAVYAMQLSSAAKAARRLWKRAPLTEELPAIRSVSDIAWAFWNRAHDSKGLENTKYLFVAMIINKETNQHVKRALGTPSPPKDEPDGWPGHNFNMDTDEGKALLGSPVGRWAGYFLMQHKRQLGGNKYISNVRVFKSEKEGSWPYFLFYVEGPSIAPIWKRSTSTDSVEGSVDTAPKVIMRSEDGRNVVREHVVWADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBR9</accession>
    <name>W6ZBR9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_90785</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the MSS1-MTO1 complex that catalyzes the 5-carboxymethylaminomethyluridine (cmnm(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MnmG family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686287.1">
        <property type="nucleotide sequence ID" value="XM_007688097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBR9"/>
    <dbReference type="STRING" id="930090.W6ZBR9"/>
    <dbReference type="GeneID" id="19127750"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90785"/>
    <dbReference type="eggNOG" id="KOG2311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007831_2_2_1"/>
    <dbReference type="OrthoDB" id="3329at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070899">
        <property type="term" value="P:mitochondrial tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000145">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000002">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="entry name" value="GidA associated domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049312">
        <property type="entry name" value="GIDA_C_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047001">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00136">
        <property type="entry name" value="mnmG_gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="GLUCOSE INHIBITED DIVISION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PROTEIN MTO1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21680">
        <property type="entry name" value="GIDA_C_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="SAM_GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01228">
        <property type="entry name" value="GIDA_assoc_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain" evidence="8">
        <location>
            <begin position="585"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="666"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="666"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC47253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="685" mass="75417" checksum="A125A76DCA5595AB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC13</accession>
    <name>W6ZC13_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_8980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964111">
        <property type="protein sequence ID" value="EUC41261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692199.1">
        <property type="nucleotide sequence ID" value="XM_007694009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC13"/>
    <dbReference type="GeneID" id="19127549"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8980"/>
    <dbReference type="eggNOG" id="ENOG502S6NX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136890_0_0_1"/>
    <dbReference type="OrthoDB" id="3141857at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039965">
        <property type="entry name" value="C3H7.08c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40466">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40466:SF1">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="147" mass="16135" checksum="01F2F5936B8C49A8" modified="2014-04-16" version="1">MSSIIARSSFRAAPRLVRPAPALRRWATSAAAEGERQRSKEALKKGAKRDPELYVLLAIMSGIFGIAGWHFSRSPTSASSERTVSKATGSEPWNRDDISHSPYQYHPGGDTSVKKDAPSALNVVVIPNVTLPKELHDTYNKWGKDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCG2</accession>
    <name>W6ZCG2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_8881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964104">
        <property type="protein sequence ID" value="EUC41421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692063.1">
        <property type="nucleotide sequence ID" value="XM_007693873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCG2"/>
    <dbReference type="STRING" id="930090.W6ZCG2"/>
    <dbReference type="GeneID" id="19127349"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8881"/>
    <dbReference type="eggNOG" id="ENOG502SPSE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029138_1_0_1"/>
    <dbReference type="OrthoDB" id="2548233at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034:SF1">
        <property type="entry name" value="CONDENSATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="51063" checksum="5FB508063AA01C9E" modified="2014-04-16" version="1">MPDCAWKETRPGRWERPQSYLEKMNILTRNVPNAIGRDNWAKNAVAKLKFHPDIKDPAAYLKTAWKQVRYNHPEIAAFPYNGNYVYRVGDAESIALWVSATFSVAEGKTVDELLGRIPRNEQMMCYFLPDTSEVMIWSPHYRVDARGAIFCLNHLVESLANMNPELVFGGCAKNLTPSMEDTLHINHEITPAIEAQAESRLAALEPHKPALELKPKVKSQRPGYTQRHFVKLSKSDTKLVMDCCDNAALALDVTLHAALVNAVVKLAPTDEARSFMASFHYNLRTLIPEGEAPENSPTSYTSVLTTEVVVSPWTDFDSYYAQLAPVYATGYAPYLGSSPYFHKLLEQRLTDSNLGSNGETDGQLQPRFAFLGNIDDKLSTNIGDGLVQVEDFWLGAETLTLRMMVHSWIWQGQLVLSVCYNQNYWDKDIAESLLQGMQETLIDVALRKGVGKVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCZ7</accession>
    <name>W6ZCZ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">R3H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_36983</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFX1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688194.1">
        <property type="nucleotide sequence ID" value="XM_007690004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCZ7"/>
    <dbReference type="STRING" id="930090.W6ZCZ7"/>
    <dbReference type="GeneID" id="19123157"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36983"/>
    <dbReference type="eggNOG" id="KOG1952">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005714_2_0_1"/>
    <dbReference type="OrthoDB" id="6512771at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="CDD" id="cd06006">
        <property type="entry name" value="R3H_unknown_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.50:FF:000006">
        <property type="entry name" value="NF-X1 finger transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034078">
        <property type="entry name" value="NFX1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034077">
        <property type="entry name" value="R3H_FAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360:SF12">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR NF-X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01422">
        <property type="entry name" value="zf-NF-X1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="R3H" evidence="11">
        <location>
            <begin position="827"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="913"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1039"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1083"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1091"/>
            <end position="1103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC45309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1167" mass="128066" checksum="2BED2E47E75AE7A2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDP0</accession>
    <name>W6ZDP0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">INO80 complex subunit F domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_3135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
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        </subcellularLocation>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        </source>
    </evidence>
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        <source>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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        <source>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
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    <accession>W6ZE32</accession>
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        <recommendedName>
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        <name evidence="3" type="ORF">COCMIDRAFT_71786</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
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                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="entry name" value="DUF7587"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40781:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24494">
        <property type="entry name" value="DUF7587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="7"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="182" mass="19760" checksum="36EE67740C580D0E" modified="2014-04-16" version="1" fragment="single">TTAPTAIPPLVYRVHRSTSQTRYSFSTGFSAKNQTTIVNYTSALSRFGLAHLNQQTNISSPFISVYDNAAHAEAVARYFGERYQEDTWVVSVDPAHFARGPVFRAADLLREGGGVEAENGGGSGSSSDRKKGRGVARDGSDEWLHWGEYLVMYRIPAQAIRDQTPVAKVGDPLRRGVGVIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEB3</accession>
    <name>W6ZEB3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glucooligosaccharide oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_22270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683264.1">
        <property type="nucleotide sequence ID" value="XM_007685074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEB3"/>
    <dbReference type="GeneID" id="19120217"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22270"/>
    <dbReference type="eggNOG" id="ENOG502QVGN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_10_1_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF17">
        <property type="entry name" value="OXIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="60"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="502" mass="53857" checksum="5F018B1E38D008CB" modified="2014-04-16" version="1">MGNTVSAAQTGISTVTGGSAGIAGSAIHQCLIRAVGDNNVAFKGDPLYQVNDVKPYNLDIQITPTAVTYPSTADQVAAIVKCAAECNLPVQSRSGGHSFGNYGIGGRDGAVVVDLKHFQKFSIDKSTWQATVGSGTRLGDLTKRLGENGGRAMAYGTCPQVGTGGHSLVGGLGPASRMWGALLDHVQEIEVVLANSTIVRVSDKQHPDLFFAMKGAGASFGIATEFKFRTQAAPPNAVIYSYTFQGGSTQSKADLFKRWQKLVSDPHLSRKFASQYIIAGPIGAVITGTYFGTQAEYDSLNISSRLQTRQSNSSVEMKDWLGAVGHWSEQVALQIVGNIPAHFYAKSLAYTQKDLMSDATVDKVFKYIDTADKGGALFFMIWDLAGGAINDIAKDATAYGHRDALFFHQAYAVNLLGRLNDTSRAYLNGINDVVINSRADRDQGVYAGYVDPALGPNSATYYWDGNVNKLQYIKALVDPRNVFRNPQSVLPAGRSAKRRAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEW1</accession>
    <name>W6ZEW1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mediator of RNA polymerase II transcription subunit 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_4799</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mediator complex subunit 21 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963972">
        <property type="protein sequence ID" value="EUC46054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687385.1">
        <property type="nucleotide sequence ID" value="XM_007689195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEW1"/>
    <dbReference type="STRING" id="930090.W6ZEW1"/>
    <dbReference type="GeneID" id="19124382"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4799"/>
    <dbReference type="eggNOG" id="KOG1510">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094271_1_1_1"/>
    <dbReference type="OrthoDB" id="526653at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.10">
        <property type="entry name" value="Mediator complex, subunit Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021384">
        <property type="entry name" value="Mediator_Med21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381:SF0">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381">
        <property type="entry name" value="RNA POLYMERASE II HOLOENZYME COMPONENT SRB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11221">
        <property type="entry name" value="Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="81"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC46054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="155" mass="17650" checksum="C2112CF674AAEB61" modified="2014-04-16" version="1">MHDILTQIQDELDMLLNQMAAALRQIRENAPPSVPPGQQRLDSFAELEAREAAQHNAANDPSQPPFAPPPKPSPEQFQADIKELAQDITLKEQQIEKLIAHLPGLNWSEKEQVERMKELERQLEDLESDRVKAVKEKEMLMKMVEDKIAGVGRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEW2</accession>
    <name>W6ZEW2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TOM core complex subunit Tom6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_82455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683230.1">
        <property type="nucleotide sequence ID" value="XM_007685040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEW2"/>
    <dbReference type="GeneID" id="19126053"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82455"/>
    <dbReference type="eggNOG" id="ENOG502SY3V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183924_2_0_1"/>
    <dbReference type="OrthoDB" id="5403997at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005742">
        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020266">
        <property type="entry name" value="Tom6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17112">
        <property type="entry name" value="Tom6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6290" checksum="0FB01607F698F83F" modified="2014-04-16" version="1">MPPKYMTGKGRTVQEPSFASSTISAFTSKENRSIVTAAGMFALGVAFLHSSWAEILLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF14</accession>
    <name>W6ZF14_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase family 34 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_8277</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691370.1">
        <property type="nucleotide sequence ID" value="XM_007693180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF14"/>
    <dbReference type="GeneID" id="19126123"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8277"/>
    <dbReference type="eggNOG" id="ENOG502SHP1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039079_0_0_1"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF8">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 34 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="328" mass="37001" checksum="EC6B5B0DB8814366" modified="2014-04-16" version="1">MEAIRTAANDIRIYIPHAEDKEGEGNGSTQLAAGLDSKDGPSSSESLAAPNTKLPSSSSPSFPKFGKITATFGEPDPPYENAIASHKLHNEIHGYPHFILREKMLRGLWSKHAYIMTIIGNELAKPKDERLAWVLWHDRDTVLMNPQLPLNIFVPPSPAFDHIHMLVTNDRNGLNNGVFLCRVSAASFKFFASALSIREYQPEIQLKYTEQSGMEEVIKRENWNNIIAYVPQRWFNGFPPTKKDLAAGKPSASRPGSLLIHFASNRDGKRPERMAHWSAIAKKRTAAWDKPVEKTGYIKEITEYWDRLGKGESQQNIIEDIEGRVWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF59</accession>
    <name>W6ZF59_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HTH La-type RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_8214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964071">
        <property type="protein sequence ID" value="EUC42146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691312.1">
        <property type="nucleotide sequence ID" value="XM_007693122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF59"/>
    <dbReference type="STRING" id="930090.W6ZF59"/>
    <dbReference type="GeneID" id="19125997"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8214"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_608510_0_0_1"/>
    <dbReference type="OrthoDB" id="439993at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12291">
        <property type="entry name" value="RRM1_La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF140">
        <property type="entry name" value="ACHILLES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="5">
        <location>
            <begin position="96"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="221"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="312"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="391"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="52260" checksum="3E82A2421197D6EE" modified="2014-04-16" version="1">MADTEIAAAAASNPAETSQAEKALKVESDSKTETKSDTKAADGEEKWELNGKSGEKSTHRNDREDRNGRNSRDNRGGRGGSKGNGRNKKQNQEFDNLPESDDPAEIRAQIEFYFSAQNLATDEHMFKELEGPKNKPVSIHHICTFKRMRRFKPYSAVVEALRHSSDLVVVDDGEYSKPGSEAVKRKEPLVVPAKEGDDQKPPTTEELFYRLRSSSSNSMETSAYVKGFGEAEEAGQIALEQFFRPFGSVMVRKRRDEEGAWKGSVFVEFDSKDSQEQFLALDPKPTFNGNELTTMGKKEYIVMKCEEKGIKPDWELTEQEKYEKRKKQREANGNFSSSRGNDRRGGGRGRGSNRGGRGGRGGSDRRDNRRDRSPRRRRDRSASNDSVDSGDWNKRRDRFKNGKDDRANSKEEKKEIERDAHGVPVVKDSRTEAEIAAASNKRKAEDDYNGSPKKTKLEIKQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFR8</accession>
    <name>W6ZFR8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_86261</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684669.1">
        <property type="nucleotide sequence ID" value="XM_007686479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFR8"/>
    <dbReference type="STRING" id="930090.W6ZFR8"/>
    <dbReference type="GeneID" id="19126822"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86261"/>
    <dbReference type="eggNOG" id="KOG1947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010840_2_0_1"/>
    <dbReference type="OrthoDB" id="10257471at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000251">
        <property type="entry name" value="Ubiquitin ligase complex F-box protein GRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="77"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="6">
        <location>
            <begin position="246"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="607" mass="67259" checksum="C1A43EF4EAF1B509" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFY3</accession>
    <name>W6ZFY3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Golgi apparatus membrane protein TVP23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_33858</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Golgi membrane protein involved in vesicular trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Golgi apparatus membrane</location>
            <topology evidence="2 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TVP23 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684732.1">
        <property type="nucleotide sequence ID" value="XM_007686542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFY3"/>
    <dbReference type="STRING" id="930090.W6ZFY3"/>
    <dbReference type="GeneID" id="19122422"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33858"/>
    <dbReference type="eggNOG" id="KOG3195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074845_1_1_1"/>
    <dbReference type="OrthoDB" id="2151161at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008564">
        <property type="entry name" value="TVP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019:SF7">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05832">
        <property type="entry name" value="DUF846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC48788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="197" mass="22095" checksum="F1ABAC1EB4029591" modified="2014-04-16" version="1">METAQQEPAPGSLSWRLSSHPITLLTFLFFRASSLVVYLLGLRLLTSNFVLIFIITILLLAMDFYYLKNIAGRRLVGLRWWNEVDASTGDGRWVFESLDPDTSSRQINATDKRFFWLALYAQPVLWVVLAIVALVSLEFIWLTLVAIALVLTITNTLAFSRCDKFSQASGFASNAMYGSGLARNLAGGMISSLFNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG73</accession>
    <name>W6ZG73_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Geranylgeranyl transferase type-2 subunit alpha</fullName>
            <ecNumber evidence="6">2.5.1.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Geranylgeranyl transferase type II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_7933</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="6"/>
    <dbReference type="EMBL" id="KI964059">
        <property type="protein sequence ID" value="EUC42501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690968.1">
        <property type="nucleotide sequence ID" value="XM_007692778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG73"/>
    <dbReference type="STRING" id="930090.W6ZG73"/>
    <dbReference type="GeneID" id="19125453"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7933"/>
    <dbReference type="eggNOG" id="KOG0529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031996_2_0_1"/>
    <dbReference type="OrthoDB" id="1658at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097354">
        <property type="term" value="P:prenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF2">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="359" mass="41948" checksum="2711185D4EEFCD57" modified="2014-04-16" version="1">MASHGIARGTGPVVRSEEARQKELEQIAQYKELADSVNTKIAEKQYTIEALGLVTKLLNENPEYYTIWNHRRRVLMALVRAETPGQSPHDLLQDDLQLTFALLRKFPKCYWIWNHRNWLLRQGETLMGVEAAHKLWSGELQLINKMLHADSRNFHAWSYRRIVVSEIERLTADSEPTTENTPKSLAESEFEYTTKMIKTNLSNFSAWHNRSQLIPKILLQRNADSKARRAFLNSELSLICEAINTDPFDQSIWFYHQYLLSVLSPSCPPNHQVVQDLTNDERQKYYENEMEYIREILEDEADCKWIYEALLGLAEAYLEVDAGTGTFTTKDMKSWLGELKRLDPLRRGRWDDLEKRLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGF8</accession>
    <name>W6ZGF8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Haloacid dehalogenase-like hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_39378</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI964056">
        <property type="protein sequence ID" value="EUC42581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690899.1">
        <property type="nucleotide sequence ID" value="XM_007692709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGF8"/>
    <dbReference type="STRING" id="930090.W6ZGF8"/>
    <dbReference type="GeneID" id="19123672"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39378"/>
    <dbReference type="eggNOG" id="ENOG502SNYU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_8_4_1"/>
    <dbReference type="OrthoDB" id="1694274at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044281">
        <property type="term" value="P:small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051400">
        <property type="entry name" value="HAD-like_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46470:SF2">
        <property type="entry name" value="GLYCERALDEHYDE 3-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46470">
        <property type="entry name" value="N-ACYLNEURAMINATE-9-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="28530" checksum="CFCEAA4BCBD5D196" modified="2014-04-16" version="1">MAEEYLKTASWWFFDLDDTLHEFRKASSSAVDATLHLIIQQQTQQPIPQKDTITFADLKAAYSKVLKETTSSAFTDGKTSHEYRADRFKATLKTLGLSPTPNQITEILEVYEKILTQHLTLKPGAIPLLKFLKQQGKNVAIVTEGPQDAQQRTVAALGLEPYFDRLITTNAVGVAKVDGLFERALELLEVEGRDVVMVGDSWDRDVVPAGKAGIRCVWYAEGSGEEERVVGFGGKGEERVVVADSLGKLRGMVGGVVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGH0</accession>
    <name>W6ZGH0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Replication factor C subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_25430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686886.1">
        <property type="nucleotide sequence ID" value="XM_007688696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGH0"/>
    <dbReference type="STRING" id="930090.W6ZGH0"/>
    <dbReference type="GeneID" id="19120760"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25430"/>
    <dbReference type="eggNOG" id="KOG2035">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042324_5_0_1"/>
    <dbReference type="OrthoDB" id="761538at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000030">
        <property type="entry name" value="replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000002">
        <property type="entry name" value="Replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000136">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF1">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13177">
        <property type="entry name" value="DNA_pol3_delta2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22534">
        <property type="entry name" value="RFC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="355" mass="40334" checksum="69736C6C9BE940B5" modified="2014-04-16" version="1">MALLVDKHRPRNLEALSYHPELSDRLRALAQSGDFPHLLVYGPSGAGKKTRIVATLKELYGPGVEKIKIDARVFQTTTNRKLEFNIVASVYHLEITPSDVGNYDRVVVQDLLKEVAQTQQVDLGAKQRFKVVVINEADHLSRDAQAALRRTMEKYSPNLRLILLANSTSNIIAPIRSRTLLVRVAAPTEAEICDVLSKVGKKEGWKDVESLHQRIAKDSGRNLRKALLMFEAVHAQNEKITDQTHIPPPDWEALIEQIARQIVEERSPQRLLQVRASLYDLLSHCIDPTTIIKTLTWKLIPKTDDALKPEVIKWAAFYEHRCKMGAKHIFHLEAFVAKYMRLYESYSMGLDFDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGP8</accession>
    <name>W6ZGP8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_33539</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684415.1">
        <property type="nucleotide sequence ID" value="XM_007686225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGP8"/>
    <dbReference type="STRING" id="930090.W6ZGP8"/>
    <dbReference type="GeneID" id="19122350"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33539"/>
    <dbReference type="eggNOG" id="KOG0938">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026996_5_2_1"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09251">
        <property type="entry name" value="AP-2_Mu2_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14836">
        <property type="entry name" value="AP2_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043532">
        <property type="entry name" value="AP2_Mu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043512">
        <property type="entry name" value="Mu2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0168">Coated pit</keyword>
    <keyword evidence="2" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="8">
        <location>
            <begin position="168"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC49068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="427" mass="48025" checksum="CDAEE08C89D6A6A6" modified="2014-04-16" version="1">MLSGILIFNQKGENLIFRAFRNDCRPRLADVFRIQVISNAQVRSPILTLGSTTFSHVKHENIYLVAVTKSNANAALVFEFLYRLVGLGKAYFGKFDEEAVKNNFVLVYELLDEILDFGYPQNTETDTLKMYITTEGVKSERTMEDSSKITMQATGALSWRRADIKYRKNEAFVDVIEDVNLLMSATGTVLRADVNGQIIMRAYLSGTPECKFGLNDRLTLGEDHLQQPSGNKAGAKATRAAAGSVTLEDCQFHQCVKLGKFDADRIISFVPPDGEFELMRYRATENVNLPFKVHAIVNEVGKTKVEYSIAIRANYGSKLFATNVVVRIPTPLNTAKITERTSQGKAKYEPEHNNIVWKIPRFTGQSEFVLSAEASLTSMTNQKAWSRPPLNLSFSLLMFTSSGLLVRYLKVFEKSNYSSVKWVRVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHN3</accession>
    <name>W6ZHN3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964040">
        <property type="protein sequence ID" value="EUC43071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690390.1">
        <property type="nucleotide sequence ID" value="XM_007692200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHN3"/>
    <dbReference type="STRING" id="930090.W6ZHN3"/>
    <dbReference type="GeneID" id="19123581"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38925"/>
    <dbReference type="eggNOG" id="ENOG502SPEQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033820_0_0_1"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="475" mass="54115" checksum="D8E4B783542D5F1F" modified="2014-04-16" version="1">MANIPLHCNICPKKPNFSDVSHLLTHIASKGHLSNYYKVKVRSTNEESSRQLIEAYDQWYAEWSVEELMSERMNQKDKRRTRAKPAARSTSAPKIEAPVPRLVRRAAAAGNFLDPRLAEQQRQHTAIKVEQSPSPISQTAGPVLRNRNNFAPHMQYWPTESRASSQSYTNPDYETSSEYSDPSERRRSYQHAAASCAIEDDPADVADPMAVSESTKLKGVYWPGMDIFDSATPEMRRKRNQKKDSSVVAQLELNSLDVEAAELIFTPLGTFKRQRRISCSESDGDEVELKSESSPPMRRRPALAHLDVNTSRRSRQSNHPAFPFMDRNQYDEDYGRTSNRARASKRKRFEVFQNDSAVSFSQPSSMTYLTSAFTRQPSPSPTAPFHTYKPFNDSFQYDNKENMMPSFHQAAYGNVHSHQSTSYQYPSYAYGLGPDHHVFQYSTHLYNTANDYPQHDQDDDDDQRTITAPPSPSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHQ7</accession>
    <name>W6ZHQ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CobW/HypB/UreG nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964040">
        <property type="protein sequence ID" value="EUC43091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690392.1">
        <property type="nucleotide sequence ID" value="XM_007692202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHQ7"/>
    <dbReference type="STRING" id="930090.W6ZHQ7"/>
    <dbReference type="GeneID" id="19123583"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38939"/>
    <dbReference type="eggNOG" id="KOG2743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_3_0_1"/>
    <dbReference type="OrthoDB" id="259708at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF62">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="1">
        <location>
            <begin position="3"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="359" mass="39332" checksum="77AF7BF8FB53F3A4" modified="2014-04-16" version="1">MIPITIITGFLGSGKTTLILNLIPQLPPSYKLALLKNEYGDVKVDTALASSAAISGVQELLNGCICCNLVGQLSDALETLARDVEPDRIVIETSGSAFPATLAMEVNRLSRETGKYVLDGVMSVIDVENWKGYEDTSITAKMQARYTDLIVLNKHELVSERRLEDVEDAILALEVEPQIPRTKSRKGWVDKDIVFGLDARLAGVTEETKDGAHTHEHDHGHSSEVEVLTVTLKSEDKAGSVDTSKLAKFLQDPTKDEVYRIKGILYAITPPKSLDTTPASTQQVPEGRARYILNWAFGRWTFTPVALPASEESKEEPALRLTVITARYESTKWKKEIESSGLVALEGNAPGTLTVEKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI04</accession>
    <name>W6ZI04_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_84063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI04"/>
    <dbReference type="GeneID" id="19126387"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84063"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF14">
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="GNAT"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="6"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="223" mass="25086" checksum="93E671407377AEC6" modified="2014-04-16" version="1">MPDPNLQISLLDPSEAEQYMRIRHEVFRDTVNHILYPRGEPSPATLSKVTDSIRTGIADGVLFLKCVDTSTGEIIAGARWRYVKPQQDGAAQRTWEEVDTGLALPEPFEESDPEMWNEVFSAMNANKREVLGQRPYYVLDTLVTLPQHERRGAGSMLVTWGCERADEAGVEAFLEASPTGAPLYARFGFRRVKEVAFDLRKWGGTTTIDLILMLRPAKEKTSE</sequence>
</entry>
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    <accession>W6ZIU6</accession>
    <name>W6ZIU6_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="6" type="ORF">COCMIDRAFT_90594</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963954">
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF7923"/>
    </dbReference>
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        <property type="entry name" value="Znf-CCCH_tandem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
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    </dbReference>
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        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="432"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="432"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC47324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="536" mass="59904" checksum="461505DA2F2FC24B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJU3</accession>
    <name>W6ZJU3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_89426</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG0255">
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    <dbReference type="HOGENOM" id="CLU_008455_0_5_1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000082">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000061">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF134">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="553"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="129"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC47704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="590" mass="64980" checksum="FF7005FE2A6CB407" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJU4</accession>
    <name>W6ZJU4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_82351</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683213.1">
        <property type="nucleotide sequence ID" value="XM_007685023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJU4"/>
    <dbReference type="STRING" id="930090.W6ZJU4"/>
    <dbReference type="ESTHER" id="cocmi-w6zju4">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="19126033"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82351"/>
    <dbReference type="eggNOG" id="KOG4389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_6_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005151151" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="27"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="22"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="561" mass="61775" checksum="AC3677323A18F0DA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKI0</accession>
    <name>W6ZKI0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal protein L7/L12 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_88658</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685529.1">
        <property type="nucleotide sequence ID" value="XM_007687339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKI0"/>
    <dbReference type="STRING" id="930090.W6ZKI0"/>
    <dbReference type="GeneID" id="19127323"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88658"/>
    <dbReference type="eggNOG" id="KOG1715">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086499_0_1_1"/>
    <dbReference type="OrthoDB" id="250175at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L7/L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_bL12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_bL12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 oligomerization" evidence="5">
        <location>
            <begin position="48"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="4">
        <location>
            <begin position="116"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC47984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="19429" checksum="F2E1A47335AA1905" modified="2014-04-16" version="1">MAAPASRALRRCICTAKQTAYVRPTIGATQQRIQRRWQSDAAAPTNPKIATIVDQISQLTLLETADLVSTLKTRLNIPDMPMGGFVAGPGSAGPAAAAAPAEEEEAAPAAQEKTLFNLKLEKFDPAAKPKVIKEVKAMLGLSLVDSKKFVESAPKVLKEGVPKEEAEKIVETLKALGATVVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL57</accession>
    <name>W6ZL57_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_2861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685201.1">
        <property type="nucleotide sequence ID" value="XM_007687011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL57"/>
    <dbReference type="GeneID" id="19121337"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2861"/>
    <dbReference type="eggNOG" id="ENOG502SUWQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171231_0_0_1"/>
    <dbReference type="OrthoDB" id="202195at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="113" mass="13179" checksum="C6D58F5F87EA88F5" modified="2014-04-16" version="1">MFKATRALSMQPTRMMAMQPSRMMAMQPTRLMAMRQSPQLFVRQTMALRSPVPKEEHSAHTVSQRLRQLKNIPTEIWPLIVVLGVAIVMAFFSITRKLWVDKTLRLKRQGKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL66</accession>
    <name>W6ZL66_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_23970</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685215.1">
        <property type="nucleotide sequence ID" value="XM_007687025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL66"/>
    <dbReference type="STRING" id="930090.W6ZL66"/>
    <dbReference type="GeneID" id="19120524"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23970"/>
    <dbReference type="eggNOG" id="KOG1666">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075474_0_0_1"/>
    <dbReference type="OrthoDB" id="430637at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007036">
        <property type="term" value="P:vacuolar calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000002">
        <property type="entry name" value="Vesicle transport through interaction with t-SNAREsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="128"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC48259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="226" mass="25876" checksum="99A13BBF6C04D058" modified="2014-04-16" version="1">MSNLIDADAGTERFSGYEAELKLVQADLSQQIDQIKETTGEPRKAAISRAERALEEAEELIGQMRLEKSNIPANLKSKYNARFRNFEHDLDTSKRKLQTYTSDRSRLFGDRYTDNPDGGDAQLEQRQQLLSGTDRLNRSSNRLRESQRIALETEQIGASTLGDLHRQREQITNTRERLLESEGYTDRSIKTLRGMARRMATNRIITIAIITVLVLLIIAVIYSKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLF2</accession>
    <name>W6ZLF2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione-specific gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_80614</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.2.7" evidence="1"/>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682582.1">
        <property type="nucleotide sequence ID" value="XM_007684392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLF2"/>
    <dbReference type="STRING" id="930090.W6ZLF2"/>
    <dbReference type="GeneID" id="19125700"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80614"/>
    <dbReference type="eggNOG" id="KOG3182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070703_0_0_1"/>
    <dbReference type="OrthoDB" id="1933483at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061928">
        <property type="term" value="F:glutathione specific gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006840">
        <property type="entry name" value="ChaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192">
        <property type="entry name" value="CATION TRANSPORT PROTEIN CHAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192:SF2">
        <property type="entry name" value="GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04752">
        <property type="entry name" value="ChaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="265" mass="29516" checksum="808047C029190321" modified="2014-04-16" version="1">MTTEHEKEIESFGANNDFWIFGYGSLIWKPPPHYDQRLPGYIEGYVRRFWQVHHRGTPEAPGRVVTLIDRAHWETLGDQHDAPSRVWGAAYHIPARHVESVRKYLDLREINGYSIQFTPFHPAVSSATAAPEEVPAEDSSSLPSTAIKVTSTESLVPEPECIKCLVYIGLPENPQFLGAQDPDALARKILQSKGPSGENREYLYNLDVALLGLSEDSGDAHVSDLVGRCRALEEEMGIVGGNEGEKSSEVLHRVGSIEEQEEVEK</sequence>
</entry>
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    <accession>W6ZLQ6</accession>
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        <recommendedName>
            <fullName evidence="4">Nucleoporin NUP37</fullName>
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            <taxon>Dothideomycetes</taxon>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="HOGENOM" id="CLU_007901_1_0_1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="56"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="663" mass="71064" checksum="44974004E1A2E9CC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
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        <name evidence="2" type="ORF">COCMIDRAFT_80603</name>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010972">
        <property type="term" value="P:negative regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF11">
        <property type="entry name" value="PROTEIN DSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="738"/>
        </location>
    </feature>
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        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
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        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
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        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
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        <location>
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            <end position="302"/>
        </location>
    </feature>
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        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
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        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
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        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="709"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="724"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="738" mass="80640" checksum="74C159ECF50FF24A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMH9</accession>
    <name>W6ZMH9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">DNA replication regulator SLD2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_31449</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Has a role in the initiation of DNA replication. Required at S-phase checkpoint.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SLD2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the proteasome subunit S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682138.1">
        <property type="nucleotide sequence ID" value="XM_007683948.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZMH9"/>
    <dbReference type="GeneID" id="19121871"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31449"/>
    <dbReference type="eggNOG" id="KOG3151">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_348830_0_0_1"/>
    <dbReference type="OrthoDB" id="8775810at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902977">
        <property type="term" value="P:mitotic DNA replication preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22289">
        <property type="entry name" value="RecQL4_SLD2_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.990:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA replication regulator Sld2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021110">
        <property type="entry name" value="DNA_rep_checkpnt_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040203">
        <property type="entry name" value="Sld2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28124">
        <property type="entry name" value="DNA REPLICATION REGULATOR SLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28124:SF1">
        <property type="entry name" value="DNA REPLICATION REGULATOR SLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11719">
        <property type="entry name" value="Drc1-Sld2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="12">
        <location>
            <begin position="611"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="53"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="286"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="476"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="387"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="514"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC51310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="808" mass="89996" checksum="107DA7B9CBF1B0C9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMI5</accession>
    <name>W6ZMI5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_23516</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMI5"/>
    <dbReference type="GeneID" id="19120449"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23516"/>
    <dbReference type="HOGENOM" id="CLU_1517620_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="177" mass="19176" checksum="162518849562A45A" modified="2014-04-16" version="1">MFRALAVVSHVCPRSGDAAVRFAGLPSGITRVGRALAAPFQTPAARQQILISVTLPAPHSPDWPSKIQIVTDTRFVTTAAHPLTTLVAARVQSSREPVPIFCSSIQQGRTMSAQTHYATVNSCPWSNAYSRVPDTSQDHRCQNSAELRIKVPRLLAEHAVGLTRVIPSLSASNCWQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMK0</accession>
    <name>W6ZMK0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_97270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688704.1">
        <property type="nucleotide sequence ID" value="XM_007690514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMK0"/>
    <dbReference type="STRING" id="930090.W6ZMK0"/>
    <dbReference type="GeneID" id="19129024"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97270"/>
    <dbReference type="eggNOG" id="ENOG502RVGM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022749_0_0_1"/>
    <dbReference type="OrthoDB" id="4138492at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF11">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="301"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="565" mass="60524" checksum="FB40DC526023C8F7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMN0</accession>
    <name>W6ZMN0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED4</name>
        <name evidence="11" type="ORF">COCMIDRAFT_21334</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682102.1">
        <property type="nucleotide sequence ID" value="XM_007683912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMN0"/>
    <dbReference type="STRING" id="930090.W6ZMN0"/>
    <dbReference type="GeneID" id="19120043"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21334"/>
    <dbReference type="eggNOG" id="ENOG502SCD7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057381_0_0_1"/>
    <dbReference type="OrthoDB" id="1929813at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019258">
        <property type="entry name" value="Mediator_Med4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13208">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13208:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10018">
        <property type="entry name" value="Med4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="125"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="242"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC51355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="284" mass="31609" checksum="6F4E01DCAF28729C" modified="2014-04-16" version="1">MDDVLNEQFGRVERALTTLVDSIAAYNPATQAAIDLVAADDQLSDGLDQLARHQANHGRIQALRAEADALEAQLRDSVRKLAELRRELFNTPATTFPPESRAVPFDELLQYATNISRYTVPPTYRERVPTTDKDDDDVGSSGAPTNGMNTPAIVPDAVDLPNDSSEAQKAGEDADGAVPDITAEEEEWLRKLKASNLAWYPWPSTDKIRNGILYRLSYWREKGNDLDQFDIPAYLEEQRKKALGNEASLEETPAEPTEEQPHREAARPTRPLSAFTGLDDMDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMS6</accession>
    <name>W6ZMS6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_79662</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682211.1">
        <property type="nucleotide sequence ID" value="XM_007684021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMS6"/>
    <dbReference type="STRING" id="930090.W6ZMS6"/>
    <dbReference type="GeneID" id="19125520"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79662"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_1_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="17"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC51293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="355" mass="38430" checksum="9B7C93AECC22A4A2" modified="2014-04-16" version="1">MSSTLEQKTMRAQQYDARDNKLHLNEVPIPQPREHELLIKMQCASLCHSDVMLFEPNEQGLILGKNPVTIGHEGTGKVVATGSGEVAKKFKEGDAVGFLCAVDCCFECYSCKNVSNIWCSTGQTKIQGFSADGYFAEYAVVDAREAIVLPENLDPKTSAPLFCAGVTAYHGIADCELPAGSWLAVIGCGGLGHMGIQYAKAMGHKVIGIDITDVAVEEAKSCGADYTFNSMTDKDYQKKILELTGGGVHAAVNFTASKKSYDDCPAIVKPGEGMIMVVGIPQKPLEFNGLDIAMGRYKVKGSNNGTCYNMREVIEFSAKHNIKAHLTAFPLEEVPKMVELMNSHQAKGRMGVIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN96</accession>
    <name>W6ZN96_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DlpA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI963992">
        <property type="protein sequence ID" value="EUC45051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688434.1">
        <property type="nucleotide sequence ID" value="XM_007690244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN96"/>
    <dbReference type="GeneID" id="19123197"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37193"/>
    <dbReference type="eggNOG" id="ENOG502S2PM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072626_0_0_1"/>
    <dbReference type="OrthoDB" id="1476984at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047443">
        <property type="term" value="F:4-hydroxy-4-methyl-2-oxoglutarate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.40">
        <property type="entry name" value="Ribonuclease E inhibitor RraA/RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254:SF4">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="114"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605493-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="25213" checksum="237E273DA3AA7994" modified="2014-04-16" version="1">MASPKWKKLYEYAACDLADGLLKLHVPGAGFLTDIRPLLHTASIPKPEPRKVLAPASTFLMVPKATKSFPAPPQMPGNIPASNLSDSRPYADYTENGTIVVISQPPGQSCAVVGGIMAARMQHLGAEGIVVDGRVRDISALNQTKLPIWSKATSVIGAGAETKFHAHNVPVKIGETIVEAGDIIMIDPFENGVVAVPQAKVDELLELLPKLVEADEKVTADVGNGVSVEEAFKRHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNA6</accession>
    <name>W6ZNA6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
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    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889960" evidence="1">
        <location>
            <begin position="21"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="100" mass="10107" checksum="DF1260EE60BB6983" modified="2014-04-16" version="1">MKFTNAVVAFNVAALTNALAISPRQNNLQTFTGAIGGVSATPVLNSGNANRPFSVGGDTFVNAAAALARSCDQQFNGCANLANGGDDNVSVAQCATQKSE</sequence>
</entry>
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        <name evidence="1" type="ORF">COCMIDRAFT_26660</name>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC45071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="110" mass="12125" checksum="AC8C6C0DAAF6A81C" modified="2014-04-16" version="1">MSISKTRHQCHEPLITGKSCHKTIVHSVSSLRFSLPRRISKSIAGRLNNAALSMYMARVCTRTPRIPARAYCVVGPKLVDTSDKLRNRLLLHGAAGSLSIMCTLQNVHGM</sequence>
</entry>
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        <recommendedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF83">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-0472">Membrane</keyword>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="336"/>
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        </location>
    </feature>
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            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
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            <end position="350"/>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="41874" checksum="69E10D263FEE3C67" modified="2014-04-16" version="1">MAKLPKPPKSFPIKSTIPTKPAAPLSRRFPRTQPTAEHLLRAPENQTPEQAAKRVWAARPRLSDLQRLSDEELRSAQHQAKLRQWRQWPMFGIGLIAFGMGTYATMLWTSLTHEADLKDLPADLSDRFDKEAEGYDEKVDTSEMLLFLTRKRKKLTAMAKGHVLEVAVGTGRNIPYYKTKQCATVTLLDSSGPMLEVARRKWNDTHKEYFSRVFFKHQSAIDPITPPYGAQDGYDTVLQTMGLCSTPEPVKLLQNLEASTNEDGQILLLEHGKSHYEWLNKMLDKTAPAHADEHGCWWNKDIGKIVEESGLEVVEMKRYNFGTTWWLQLKPRKGIRQKRTTAGSGEQPATAQAGPAVERKPWWWLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ42</accession>
    <name>W6ZQ42_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="8" type="ORF">COCMIDRAFT_84123</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685721.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZQ42"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_84123"/>
    <dbReference type="eggNOG" id="ENOG502QVYJ">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="fungal_TF_MHR"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF9">
        <property type="entry name" value="TAH-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
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            <dbReference type="PROSITE" id="PS50048"/>
        </source>
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            <dbReference type="EMBL" id="EUC49619.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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</entry>
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    <accession>W6ZQB0</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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    </dbReference>
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            <begin position="36"/>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49674.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="30967" checksum="A10ECD8ADD89B32D" modified="2014-04-16" version="1">MAEPIPAEEQSNYETFRDCMSDVVLKALAAPTEKPKPKKKRHAKKGSKSGKSDIAPEEKATANSNTDLQTNDAEDLGEFIEYLSALIFPSLPASLRTLSHTLMTTTPSLEESYSTPLSAQTRNLVLSSIPPVAIDSLESYALLPPSSDQTDHHNLVTPLFTAYINAVTAPPPIWSSTRTSACELCGRDWVPLTYHHLIPKSAHARVLKRGWHAEEMLNSVAWLCRACHSFVHGLVGNEELARGFYTVELIVAGGVHGDGEIKERVERWVRWVGGVRWKSR</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nuc_rcpt_coact/corep"/>
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        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
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        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="435"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        </location>
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        </location>
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        </location>
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        </location>
    </feature>
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            <begin position="481"/>
            <end position="496"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="524"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="816" mass="89504" checksum="E3E351D05A82A3DC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSC2</accession>
    <name>W6ZSC2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL28m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_82025</name>
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    <organism evidence="7 8">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC50414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSC2"/>
    <dbReference type="STRING" id="930090.W6ZSC2"/>
    <dbReference type="GeneID" id="19125980"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82025"/>
    <dbReference type="eggNOG" id="KOG3278">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_561563_0_0_1"/>
    <dbReference type="OrthoDB" id="361870at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="54S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00830">
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    </dbReference>
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        <property type="entry name" value="L28p-like"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
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        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
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        <location>
            <begin position="210"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="496" mass="55328" checksum="8403772054326832" modified="2014-04-16" version="1">MHARCQLLSGRIPAAGAVGRSAHQAQRTYATTAPAPAPAVKNPLQRRRGGDLGSHLPKNVIPKDAYIPAYPYGEHRLFKQANKGLYGEQMIRFGNNVSKDTETKTRRKWQPNVLSKSLYSVALKKKIKLRITAKVLKTMDREGGLDEYLLKDNVARIKELGPMGWALRWTLMQKPEVIERLRADAAALGLDQATIDKQWPTPQMMAARKAAEGTPELESEKFPESEEQQMWAPEKADAPESPSLETELLEKYEKGTEAFAANEYLKAVKAAQRYLTRGLVDSEEEGLKLAFIRAKERKEAVVTLKQKTYRRYKEAGFTVEDLQEIRNRFNLPNIKDHTAMKIAYNQRKRKEIEEAGSIEAWKAAARPDKQAAEATYAARVQAAGGEAAFRAAQKAEYAKVIAEAETASTNQSLDAERRRYLERAIHKADLAIKAKAAGGQDDYVESMLEDRRRTASASDGLRDIYKGSVQEKTARGDAWAALVNSSNKAASSQPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZT96</accession>
    <name>W6ZT96_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_4088</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZT96"/>
    <dbReference type="STRING" id="930090.W6ZT96"/>
    <dbReference type="GeneID" id="19123959"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4088"/>
    <dbReference type="eggNOG" id="KOG1996">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039851_0_0_1"/>
    <dbReference type="OrthoDB" id="5411533at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
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        <property type="entry name" value="RBD_domain_sf"/>
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        <property type="entry name" value="RBM17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288:SF8">
        <property type="entry name" value="SPLICING FACTOR 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288">
        <property type="entry name" value="SPLICING FACTOR 45 SPF45"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="G-patch" evidence="4">
        <location>
            <begin position="339"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="443"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="162"/>
        </location>
    </feature>
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        <location>
            <begin position="176"/>
            <end position="342"/>
        </location>
    </feature>
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        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
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        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
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            <begin position="245"/>
            <end position="258"/>
        </location>
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            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
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        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="56426" checksum="EA3DB412288889DB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTD8</accession>
    <name>W6ZTD8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase III subunit Rpc5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTD8"/>
    <dbReference type="STRING" id="930090.W6ZTD8"/>
    <dbReference type="GeneID" id="19124965"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_647"/>
    <dbReference type="eggNOG" id="KOG2354">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045565_1_0_1"/>
    <dbReference type="OrthoDB" id="340681at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006886">
        <property type="entry name" value="RNA_pol_III_Rpc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04801">
        <property type="entry name" value="RPC5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="37942" checksum="A77DB8F58CBC7B27" modified="2014-04-16" version="1">MDVEDDDPVVAEYDVYITPDVAEQQLYVLQYLNRPPDQPFTKATESQPTELRIKKDSGFIEVDVPINIHRNYNRLAGVRWGEAMRKTKGFGQKAFGIASGFERTMPRSANRPGAAGEGAPVAPVTADDDDNIEEYVTHFEDANEKGHVLNTQTFGGQILHEDGKGPSYMLGTFRDNELHLTRIDGLVQLRTQFHHIDASAQLEAVQRRREKESQEGAKLAEPKAFLAQVKKTGGDTAAELTQAFMKATNQEQWQRLNYFDENDERAFESYHERLFIQDVASAPKLQAKIDNSGFLDTISTSGKGGKKKSRRSIQDLVEISDESDEDEEEKEAAEAKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUU7</accession>
    <name>W6ZUU7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium-binding protein NCS-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_151</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682067.1">
        <property type="nucleotide sequence ID" value="XM_007683877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUU7"/>
    <dbReference type="STRING" id="930090.W6ZUU7"/>
    <dbReference type="GeneID" id="19119885"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_151"/>
    <dbReference type="eggNOG" id="KOG0044">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072366_0_0_1"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000009">
        <property type="entry name" value="Visinin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="158"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="194"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="242"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC51354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="288" mass="33083" checksum="BF1576C7EBD97415" modified="2014-04-16" version="1">MQPRLDIYNRSDKHARAPSAPSIPSQEFATPFLGHRHPPLKFARRHHLHPPHLGEAGHAHYRDVQRVALANAVREFDEGLGLCCHIACLEIQNQLLIVRYYSQSKLSQQELADLQKATHFDKKELQQWYKGFLKDCPSGMLTKEEFQKIYKQFFPFGDPSSFADYVFNVFDADKSGTIDFKEFICALSVTSRGKMEDKLDWAFQLYDIDGDGKISYEEMLAIVEAIYKMVGSMVKLPEDEDTPEKRVKKIFRMMDKDENGSLDMAEFKEGSKRDETIVSALSLYDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVK8</accession>
    <name>W6ZVK8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_34717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685681.1">
        <property type="nucleotide sequence ID" value="XM_007687491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZVK8"/>
    <dbReference type="GeneID" id="19122626"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34717"/>
    <dbReference type="eggNOG" id="ENOG502SCZR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162820_0_0_1"/>
    <dbReference type="OrthoDB" id="5355526at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="78" mass="8639" checksum="EC3EA8E185A3FBB6" modified="2014-04-16" version="1">MCYQVVERYSVCRCLYYKHAIDPCVAHGQRGHMVQEKTVLVGYACNTHSSNRPNIAYHAGGHLDSGYGSSSCSFGPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZXK5</accession>
    <name>W6ZXK5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_23588</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Peripheral membrane protein</topology>
            <orientation evidence="1 9">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M76 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684813.1">
        <property type="nucleotide sequence ID" value="XM_007686623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZXK5"/>
    <dbReference type="STRING" id="930090.W6ZXK5"/>
    <dbReference type="MEROPS" id="M76.002"/>
    <dbReference type="GeneID" id="19120464"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23588"/>
    <dbReference type="eggNOG" id="KOG3314">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079125_0_0_1"/>
    <dbReference type="OrthoDB" id="285308at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="241" mass="27908" checksum="4649544A343774A1" modified="2014-04-16" version="1">MSKPETAPDGASLSAMAQPPPAKIDPVYYTWSSAFNILLGRMTGQRDISLEKNYFGEMDTIKADSICRRCESNKEYLLQYSPVIRFMQDEVYKLGGDLNKDNILCRMCTNEQSGGFSLEHGILLCANKFRNRGHQEDTMAHEMVHAWDHLKFKVEPDNLRHQACLEIRASTLSGECRFAREFFTRNQWRITEQLQACVRRRATLSMLARPGIRDQEHAGKVVNEVWESCFRDTRPFDEIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZM8</accession>
    <name>W6ZZM8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_23152</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Znf_CCCH"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
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            <end position="193"/>
        </location>
    </feature>
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            <begin position="164"/>
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        </location>
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        </location>
    </feature>
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            <end position="252"/>
        </location>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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</entry>
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    <accession>W6ZZR9</accession>
    <name>W6ZZR9_COCMI</name>
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        <recommendedName>
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        </recommendedName>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="HOGENOM" id="CLU_068279_3_1_1"/>
    <dbReference type="OrthoDB" id="3774232at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    </dbReference>
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        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="4"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="193" mass="22262" checksum="2D396F603989AB80" modified="2014-04-16" version="1">MDPRDPIVTLNVKNSAGGTDGLYVHQGVLCKSSKFFQTAMKKEWAGLKDEPHVIDLPEDCTETVKMYIEWLYTGKISSKLCMTMEECNFDDKNFSREAEKNFIVLAKAHIYGKKIIDSVFTRQMFNEMRETLFCYMRWPTADSLLRRIIASKLAYHLEEKDELDAGLLDVLDKYPHQALVDTLKAIARPCRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A054</accession>
    <name>W7A054_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_84672</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51220"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
            <dbReference type="ChEBI" id="CHEBI:34718"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:133977"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 glutathione + H2O2 = glutathione disulfide + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16833"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="EC" id="1.11.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A054"/>
    <dbReference type="STRING" id="930090.W7A054"/>
    <dbReference type="GeneID" id="19126504"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84672"/>
    <dbReference type="eggNOG" id="KOG1752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026126_7_2_1"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
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        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="8">
        <location>
            <begin position="53"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC49386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="138" mass="14788" checksum="37E44AD39CB7FC19" modified="2014-04-16" version="1">MAKDGSTVVTGRSKHPTTAKISFLRHFFTRAPSPTTMSATKTKVQSIIDENPVAVFSKSYCPYCNQAKQLLSASGAKFYAIELDQVDDGSAIQSVLADITGQRTVPNIFIAQQHIGGNSDLQAKKGELNTLLKDAGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1K1</accession>
    <name>W7A1K1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Histone-binding protein RBBP4-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_1319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683486.1">
        <property type="nucleotide sequence ID" value="XM_007685296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A1K1"/>
    <dbReference type="STRING" id="930090.W7A1K1"/>
    <dbReference type="GeneID" id="19119840"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1319"/>
    <dbReference type="eggNOG" id="KOG0302">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025272_1_0_1"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051972">
        <property type="entry name" value="Glutamate-rich_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903:SF1">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="7">
        <location>
            <begin position="87"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="299"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="344"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="399"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="152"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="493" mass="54203" checksum="20A049BB0EF85084" modified="2014-04-16" version="1">MAKRAAESEQELEAIKNGERPMEVDAQNEAGEFEDEFEDEFESEDEILEAGVDGRPDEEREAEERENGMDIDKGTFIPGRHKLSPGETLNPDLSTYDMLHTLEAPWPCLSCDIVPDNLGSDRKTYPATVYAVAGTQAARGRDKENQIMVMKMSSLSRMEKEDEEDEDSDSDDEASDPILETKSIPLTSCTNRIRAHQTPQATSAQPPTTLTAAMTESGQVLIHDVTPHLTSFDTPGTTISPAQNKPVCTIRAHGSNEGYALDWSPLIPEGKLLTADCAGKIFATTRTQGGGFVTDTTPYTGHQGSVEELQWSPTEKTVFSSASSDGTVKIWDTRVKSRKPVLSVQASKTDVNVLSWSHQTAHLLASGADDGEWAVWDLRQWKPSTDMSSDKKPSPVASYTFHKEQITSVEWHPTDDSIVLVCAGDNTLTLWDLAVELDDEESKYTAGVQDVPPQLLFVHYMEQIKEAHWHPQIPGAIMATGGSGFNVFKTISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2K3</accession>
    <name>W7A2K3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_82645</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683352.1">
        <property type="nucleotide sequence ID" value="XM_007685162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2K3"/>
    <dbReference type="GeneID" id="19126097"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82645"/>
    <dbReference type="eggNOG" id="ENOG502S12X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034313_0_0_1"/>
    <dbReference type="OrthoDB" id="411785at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF84">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="31996" checksum="403C2C59BEF01037" modified="2014-04-16" version="1">MPSNPPPSFGSQAYWDERFTSNMDPFDWLEEPNALDPYLVDALDSSRADKPEILHIGCGTSLLSLHLRSHVDHPGQIHNVDYSDVAIQIGKAREEEIYQYQSQQKGNTQGTHAPCMRWDVVDLLDYKSLLRACSRASYSVVVDKSTSDAIACCDDISVPVPYPVAIRSHDPVQLSSAVSKEPIHPLAVMAVNLALVTKPGARWIALSYSQDRFDVLDAASDVVPKGMTFPHPADLWRLVERREIDDVESPAQVDEKDGSVTYRPKVCNVVYILERTGIPLFVRGEHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W7A448</accession>
    <name>W7A448_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_32023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682698.1">
        <property type="nucleotide sequence ID" value="XM_007684508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A448"/>
    <dbReference type="GeneID" id="19122009"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32023"/>
    <dbReference type="eggNOG" id="ENOG502RJ07">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_710111_0_0_1"/>
    <dbReference type="OrthoDB" id="3800185at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="395" mass="43158" checksum="0B4B250BEB218523" modified="2014-04-16" version="1">MASKANCTLPGFMPNMVPHVSGTSGANVANTKTHVPEPTLQEHDSTSGTALLHSYPSGDAHSIPAPYGSAPPHRVESSPSPVMAHNTPGLSSCMTESNGASHAGKTPSGSQPALSQHVTTHPPAGKTIQVAPVPSKASDVKFSRLPSSNIPRKAPLRGNSGPSKSPSQDTSRKISRPRQKQPKSGQEESTDTAAPTQKRRQVPTEKSQGTKRQSPVVLIRAGRSGKGTKKDDNQESRNDQKEEGALRKKRKCNENENDANSTTASGKITHEGRKVTKNFLQGTKIARSTYVPSSLLPNRTIRRRPMYDYDVPLELEGIRRALGPDDWNEYVYLMESLWLNKVTAHEFEQGAKPLFQLHLDGMRKRMNSVMVVKMIMPRLEQVREELMAMSSGLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W7A487</accession>
    <name>W7A487_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Endosomal/vacuolar adapter protein YPT35</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">PX domain-containing protein YPT35</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_80589</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YPT35 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682579.1">
        <property type="nucleotide sequence ID" value="XM_007684389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A487"/>
    <dbReference type="GeneID" id="19125695"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80589"/>
    <dbReference type="eggNOG" id="ENOG502S5IQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070610_0_1_1"/>
    <dbReference type="OrthoDB" id="10254720at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07280">
        <property type="entry name" value="PX_YPT35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037917">
        <property type="entry name" value="Ypt35_PX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="PX" evidence="11">
        <location>
            <begin position="71"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC50896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="181" mass="20033" checksum="AFE718BE31C781EE" modified="2014-04-16" version="1">MEPAKSETREPSPPSPDGSSVAVVPPYWQQHQRSASYRSTCSADNNRPAPIGLEDHTHDGSDHCKALWAKGVTIDDYVVVSGTAPAIGAYVVWNCTVQTLDGGPMKIRKRYSEFEELHAKLLQTFPHAAGSLPQLPPKSVISRFRPRFLEKRKQGLSYFLNCVLLNPEFAGAPVLKDFLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4B5</accession>
    <name>W7A4B5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Benzoate 4-monooxygenase bphA</fullName>
            <ecNumber evidence="12">1.14.14.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Benzoate-para-hydroxylase A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Cytochrome P450 monooxygenase cyp53A1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_80498</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>benzoate + reduced [NADPH--hemoprotein reductase] + O2 = 4-hydroxybenzoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18033"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16150"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.92"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.92" evidence="12"/>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682606.1">
        <property type="nucleotide sequence ID" value="XM_007684416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A4B5"/>
    <dbReference type="GeneID" id="19125679"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80498"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018664">
        <property type="term" value="F:benzoate 4-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000053">
        <property type="entry name" value="Cytochrome P450 benzoate 4-monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF29">
        <property type="entry name" value="BENZOATE-PARA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 16 17" id="KW-0349">Heme</keyword>
    <keyword evidence="7 16 17" id="KW-0408">Iron</keyword>
    <keyword evidence="9 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 17" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00081895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00082391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC50951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="503" mass="57165" checksum="472B98FED7EAACAD" modified="2014-04-16" version="1">MFLTSLLLTPYTILLLPVIFYLLPYLRNWQIRDIPAPFPAAWTNLWLLYQCRRGKRFLAVHEAHQKLGKFVRIQPHHVSIADADAITQVYGHGNGFLKSEYYDAFVSIRRGLFNTRDRAEHTRKRKTVAHTFSAKSVLQFEQYIHHNLQELQYQWDRRADGAKNQGGWYNMDALNWFNYLAFDVIGDLAFGEPFGMLRKGKDEAEVAKDGKITYAPAIEVLNRRGEVSGTVGIFPAIKPYAKYFPDPFFSKGMKAIENLAGIAIARVNARLEKPSDRVDLLARLMEGRDETGNKLGREELTAEALTQLIAGSDTTSNTSCALLYHCLKHPEVVKKLQKELDTALPDPDAVPSYAQVKDLPYLDAVIKEAMRIHSTSSLGLPRLIPPGPGITILGRHFPQGTVLSVPAYTIHHSTEIWGPDADTFRPERWENITEKQKAAFIPFSYGPRACVGRNVAEMELALIVATVFRRYEFELRQDEMETREGFLRKPLGLEVGMRKRVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJM4</accession>
    <name>W6YJM4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Caleosin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_111202</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the caleosin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964329">
        <property type="protein sequence ID" value="EUC39567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693914.1">
        <property type="nucleotide sequence ID" value="XM_007695724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YJM4"/>
    <dbReference type="STRING" id="930090.W6YJM4"/>
    <dbReference type="GeneID" id="19119730"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111202"/>
    <dbReference type="eggNOG" id="ENOG502QQD0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062049_0_0_1"/>
    <dbReference type="OrthoDB" id="640742at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007736">
        <property type="entry name" value="Caleosin-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31495:SF0">
        <property type="entry name" value="BINDING PROTEIN CALEOSIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G13750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31495">
        <property type="entry name" value="PEROXYGENASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05042">
        <property type="entry name" value="Caleosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC39567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="27844" checksum="6996A1EE09EFA2D1" modified="2014-04-16" version="1">MRHSERLTDGDDGVVRSIRDVPITEQRKPFIDSKDSKLQHPGTARANLAPSVESPEGTKGWKEQHSHQTVLQQHCDFFDRDHDGILWPQDTFVGFYRLGFGVILSIVAVFVIHANFSYPTCSGWLPDPFFRLFLKNVHKDKHGSDTGTYDTEGRFLPQKFEDIFAKYAEGRDYLTIWDVSNVLKGQRCIADPIGWGGAFFEWIATYIMLWPEDGRMMKEDIRRIYDGSIFYTIAERREKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YKJ0</accession>
    <name>W6YKJ0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_31206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964281">
        <property type="protein sequence ID" value="EUC39677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693803.1">
        <property type="nucleotide sequence ID" value="XM_007695613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YKJ0"/>
    <dbReference type="STRING" id="930090.W6YKJ0"/>
    <dbReference type="GeneID" id="19121823"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31206"/>
    <dbReference type="HOGENOM" id="CLU_834166_0_0_1"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="333" mass="37256" checksum="79BE627CB5475F13" modified="2014-04-16" version="1">MFQNADNLAKSTQAFQSALTYHDLNAYFRFLRGTIVTSDGNAGRMREELPEAFSVVLQLEDLQNRLRKVSGLASFSASISIRARTPLLTALETLEAFSGVVNSRLLATKYQDDSLRKHYSYLTRDYAIAQQNIEGLRFPGFENHERLDIASIERRSNIDLRRLEEALQQVIKAIRQQPSFECFLQPLSRDEICALSREGPAVCLNISHVGSEAFLISKNTIAAIPLPGLQRPDVEKNVKILAFNSNRRRRDASLCLDKEDGADGDKIKNHNPKLHSALLNLWNHAVQPALQAPRLLRHDPKPKPLPRVRWVVSGIASLLPLHAAGSHTPGSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YKX9</accession>
    <name>W6YKX9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Fumarylacetoacetase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_10142</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAH family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964236">
        <property type="protein sequence ID" value="EUC39857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693625.1">
        <property type="nucleotide sequence ID" value="XM_007695435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YKX9"/>
    <dbReference type="STRING" id="930090.W6YKX9"/>
    <dbReference type="GeneID" id="19117871"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10142"/>
    <dbReference type="eggNOG" id="KOG1535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_436837_0_0_1"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000002">
        <property type="entry name" value="2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="8">
        <location>
            <begin position="87"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="7">
        <location>
            <begin position="351"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC39857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="63508" checksum="82683D1A19211579" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLX6</accession>
    <name>W6YLX6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4484 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_109398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964186">
        <property type="protein sequence ID" value="EUC40207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693266.1">
        <property type="nucleotide sequence ID" value="XM_007695076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLX6"/>
    <dbReference type="STRING" id="930090.W6YLX6"/>
    <dbReference type="GeneID" id="19119421"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109398"/>
    <dbReference type="eggNOG" id="KOG4704">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019791_0_0_1"/>
    <dbReference type="OrthoDB" id="2152680at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028115">
        <property type="entry name" value="DUF4484"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018626">
        <property type="entry name" value="LCHN/Anr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053056">
        <property type="entry name" value="Lipid_Metab_Assoc_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153:SF1">
        <property type="entry name" value="DUF4484 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09804">
        <property type="entry name" value="DENND11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14831">
        <property type="entry name" value="DUF4484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4484" evidence="2">
        <location>
            <begin position="407"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="550" mass="61439" checksum="1C5250369C58EC8A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YM93</accession>
    <name>W6YM93_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_41290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964171">
        <property type="protein sequence ID" value="EUC40367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693115.1">
        <property type="nucleotide sequence ID" value="XM_007694925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YM93"/>
    <dbReference type="GeneID" id="19124036"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41290"/>
    <dbReference type="HOGENOM" id="CLU_2319987_0_0_1"/>
    <dbReference type="OrthoDB" id="10365643at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="99" mass="10362" checksum="63C3445BD3283EEB" modified="2014-04-16" version="1">MASDYSVGIIHGRGGWPNGTSPHSKAGGCGSGVWDAERDILGWAIGHGLEQTKAAMVHYSGSEGGLQGAQCRHKDAKDLDGGDKSVGVVTVLARQICWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6YML6</accession>
    <name>W6YML6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_41157</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964158">
        <property type="protein sequence ID" value="EUC40522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692956.1">
        <property type="nucleotide sequence ID" value="XM_007694766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YML6"/>
    <dbReference type="STRING" id="930090.W6YML6"/>
    <dbReference type="GeneID" id="19124007"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41157"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_1_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF1">
        <property type="entry name" value="ENOYL REDUCTASE (ER) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="8">
        <location>
            <begin position="24"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="366" mass="39178" checksum="B6D1A53AF251A6F4" modified="2014-04-16" version="1">MTDSEMSVFQVPKEGKAGVVVNEGPDFRVEVQMVPVPGIKPHEVLIKLNVTGICHSDIHYMRNDWASPKMSEFGTICAGHEGAGIIVKVGHAVTTLKPGMRAGYKPIQATCGECRHCQTNEDCYCANAVFTGLMIDGSYKQYVVSPERYTTIIPDGVDAFIAAPIMCSASTMYTSIKTSGLQPGDWAVFPGGGGGLGMQGIQLAKAMGLRSVAIDTGENKRRLCLENAGADAFIDFRLTSNVTDEVIQICDGIGAHAVFVTAVQTYPSSIPMLGGRVGGRVMCIGLPPAGTQLIHVDPSQMCYKKQAVQGTLVSSMADVDKTLDLAERGLLKPIYTVYPFSKFNEVVQKLSKGEIAGRAVVDFNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YP78</accession>
    <name>W6YP78_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Homing endonuclease LAGLIDADG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_111450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964402">
        <property type="protein sequence ID" value="EUC39480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007694002.1">
        <property type="nucleotide sequence ID" value="XM_007695812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YP78"/>
    <dbReference type="STRING" id="930090.W6YP78"/>
    <dbReference type="GeneID" id="19119774"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111450"/>
    <dbReference type="eggNOG" id="ENOG502S5A9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090219_0_0_1"/>
    <dbReference type="OrthoDB" id="5274855at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03161">
        <property type="entry name" value="LAGLIDADG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homing endonuclease LAGLIDADG" evidence="1">
        <location>
            <begin position="29"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="212" mass="24389" checksum="914AA37E77FD88E6" modified="2014-04-16" version="1" fragment="single">GTNLRSQVGTGKFTKLVTSMIKLPNYNKSIIIGLLLSDGWLTFASKTNKNARLGFKQTINKASYVWFIFNELSHYCSSYPYYAERKVLYNLGFFTRGLTCFTELYPVFYINNVKIVPEDIYNLLTPVALAHLIMGDGGFKSKGIYICTDSYTIQDTVRLMNVLIIRYDFKCTLHKASNEHGYRIYISRNSLYKVKKLVKPHFIPSMFYKLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPN5</accession>
    <name>W6YPN5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_106506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964109">
        <property type="protein sequence ID" value="EUC41317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692174.1">
        <property type="nucleotide sequence ID" value="XM_007693984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPN5"/>
    <dbReference type="GeneID" id="19118876"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106506"/>
    <dbReference type="HOGENOM" id="CLU_1740177_0_0_1"/>
    <dbReference type="OrthoDB" id="3913322at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045469">
        <property type="entry name" value="Nis1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19271">
        <property type="entry name" value="Nis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889094" evidence="1">
        <location>
            <begin position="19"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="150" mass="16367" checksum="BDC64BD7412C4A6E" modified="2014-04-16" version="1">MHFTPLTLFLTTLSTASAFIESFTVPAMIAPNKPYTITFNTRFDPAYLWTDVAVTWGYNNPPGSINSVGQYPVIYHLPPNPKQAPVKLVVTAPDGIQKFNKQKKIEIVASVFTVASIVGNVGFTSFNVTIDVGDKVSDKLVTSQGFLVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQW2</accession>
    <name>W6YQW2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_10017</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964208">
        <property type="protein sequence ID" value="EUC40020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693464.1">
        <property type="nucleotide sequence ID" value="XM_007695274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQW2"/>
    <dbReference type="STRING" id="930090.W6YQW2"/>
    <dbReference type="GeneID" id="19117622"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10017"/>
    <dbReference type="eggNOG" id="ENOG502SKTW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031387_1_0_1"/>
    <dbReference type="OrthoDB" id="5386330at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF17">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="482" mass="53923" checksum="C619F19431FAF0BC" modified="2014-04-16" version="1">MPPDGNVKKERGCFQCSCRRIVCDKTEPSCRKCAKKGIECSGIGRIRFAGGVARRGRLKDCKIPKTGGDDSCKELPTTIEFQSLRWPGKERARKKRKSDLDETAQEPPTPHTINSTEMQHGRKDSLLLAPPNTNADSEADVEDIGRGYNSIVVRYSQPYEVAPWVAPIDPKLRMLFSYFSDVVAPAMVVFDDDTNGYRSLVLPMALEDDLLRRAVGVVAAQHLSHQRPELQGAAEAGRAAVISRLRNDSLQQSADKVFNKFTWATLVVLLVGETVTGSADYHFFVQMLLSLSMSNPGRDADPIISNFLQTQTHMFELLGVPLLREEVGVLTMMKASESLMSFLSFFHLPEDSEDRRIVDLIRQCFVSACNIYTRCAAGADAVSRFHNTIQEESIHQLIGVISQISPNDRGAHALVWVCFIAGAASTDQSQRDFFVHRMEQVYARTRFRNIPIAIQSLENIWARRSGERWTVCLPQLSNVLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS24</accession>
    <name>W6YS24_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_108847</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Gln) + L-glutamine + ATP = L-glutaminyl-tRNA(Gln) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="2"/>
    <dbReference type="EMBL" id="KI964166">
        <property type="protein sequence ID" value="EUC40430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693048.1">
        <property type="nucleotide sequence ID" value="XM_007694858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS24"/>
    <dbReference type="STRING" id="930090.W6YS24"/>
    <dbReference type="GeneID" id="19119319"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108847"/>
    <dbReference type="eggNOG" id="KOG1148">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_2_3_1"/>
    <dbReference type="OrthoDB" id="10250478at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990825">
        <property type="term" value="F:sequence-specific mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000007">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000183">
        <property type="entry name" value="Glutaminyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF4">
        <property type="entry name" value="GLUTAMINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="11">
        <location>
            <begin position="75"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="12">
        <location>
            <begin position="418"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="13">
        <location>
            <begin position="528"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC40430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="638" mass="72417" checksum="3A6EBE3892C7F6EF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS44</accession>
    <name>W6YS44_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964067">
        <property type="protein sequence ID" value="EUC42267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691221.1">
        <property type="nucleotide sequence ID" value="XM_007693031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS44"/>
    <dbReference type="GeneID" id="19118414"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103971"/>
    <dbReference type="HOGENOM" id="CLU_3037809_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="55" mass="6354" checksum="D96C50152CB438A7" modified="2014-04-16" version="1" fragment="single">TRYVKAQNDEALRPQQAIDLIRYTDKLSVRCLVPNSGFIYKLALNVVKKNYLLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS82</accession>
    <name>W6YS82_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_41291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964171">
        <property type="protein sequence ID" value="EUC40368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693116.1">
        <property type="nucleotide sequence ID" value="XM_007694926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS82"/>
    <dbReference type="GeneID" id="19124037"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41291"/>
    <dbReference type="HOGENOM" id="CLU_135129_0_0_1"/>
    <dbReference type="OrthoDB" id="10406855at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889175" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="13101" checksum="AD1F711FFE27AE4C" modified="2014-04-16" version="1">MCGTATPLPLARSLFLFLSLHLSPLPSRLGRKLPHTMPRPILNTSHSPTLLGSLAGPANGYRFHTGHKRELMDWPSLRVHSYLSVKVHSFAHNPTSACGFGLQEREAWLHARLIYASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSV7</accession>
    <name>W6YSV7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964059">
        <property type="protein sequence ID" value="EUC42512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690995.1">
        <property type="nucleotide sequence ID" value="XM_007692805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSV7"/>
    <dbReference type="GeneID" id="19118277"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103344"/>
    <dbReference type="HOGENOM" id="CLU_2960399_0_0_1"/>
    <dbReference type="OrthoDB" id="3665623at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="59" mass="6665" checksum="A3A453C1C304DDB6" modified="2014-04-16" version="1">MAVNARFWRANAVAPRIIDGVGLGETPRRRHGGPCTQEQRPIREMQLRQQPCHVRAGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUJ7</accession>
    <name>W6YUJ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_29999</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964115">
        <property type="protein sequence ID" value="EUC41203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692281.1">
        <property type="nucleotide sequence ID" value="XM_007694091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUJ7"/>
    <dbReference type="GeneID" id="19121601"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29999"/>
    <dbReference type="eggNOG" id="ENOG502SNAH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_25_4_1"/>
    <dbReference type="OrthoDB" id="4525788at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="63"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="363"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC41203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="391" mass="42981" checksum="C803582F932D7792" modified="2014-04-16" version="1">MIDPAGLLRGTNALVSRAGGIHVPPEVIASWPTPNYISPEERTSAAPVFLSILLVVTILVYGARMWARLTMTKNAGLDDVLISISMVPLIGLSIATILGMKIYGFQWHMWDQTPTTKTTTTYVTMAIELTYMISTILIKISILLFYRRLTGSSTTRFIYLVWACIAACILYFAAFVILIFFTCSVAVGRKDCAEEGPFIVSVTTVSTAQDLVICLLPALLISNLQMPKRQKLAVCGIFGLGLVTTLCGIMRLYYAVYLYYFTYDATWYAYYGWIWTVLETDLGLICASAPALRVFFRHSLGLISSHTGDPRSGANKTSSGILSNRATHSGPLTRSGDSKDPESQGDEIYLDSIIVERGLSSRIQERDDASQKSDSSTRNLTTIIHGPVSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVC1</accession>
    <name>W6YVC1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_111533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">To endonucleases of group I introns of fungi and phage.</text>
    </comment>
    <dbReference type="EMBL" id="KI964434">
        <property type="protein sequence ID" value="EUC39459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007694023.1">
        <property type="nucleotide sequence ID" value="XM_007695833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVC1"/>
    <dbReference type="STRING" id="930090.W6YVC1"/>
    <dbReference type="GeneID" id="19119789"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111533"/>
    <dbReference type="eggNOG" id="ENOG502SIY2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080466_0_0_1"/>
    <dbReference type="OrthoDB" id="2203429at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10445">
        <property type="entry name" value="GIY-YIG_bI1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006350">
        <property type="entry name" value="Intron_endoG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010896">
        <property type="entry name" value="NUMOD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003611">
        <property type="entry name" value="NUMOD3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01453">
        <property type="entry name" value="grpIintron_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07453">
        <property type="entry name" value="NUMOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00496">
        <property type="entry name" value="IENR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64496">
        <property type="entry name" value="DNA-binding domain of intron-encoded endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="2">
        <location>
            <begin position="68"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="277" mass="32249" checksum="C80765B85471A3F6" modified="2014-04-16" version="1">MNFKVNSKRLFNKSIVKRGYSTSSSSNSTIMSERLETIINELGLNLVYCYENLNLEETRKQILNDTRGLSGVYMIINKTTKDYYIGSASTGRFYARFCNHVIYFRGSKIVKLAIKKYDLKNFAFVVLDLYPNIVTKENNHELLRLEDKYLKLLVPNYNILTEAGSSFGYKHTEIDRQKMKDIYSDARREQIGKLNKGKNLSHETIERIREKALLKPPMSDETKKKCIVNTRPVVLYNLDRIIYGQYTTILEAAKAINCNEKTIRRALQTEKKLVKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW21</accession>
    <name>W6YW21_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_38486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964024">
        <property type="protein sequence ID" value="EUC43617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689880.1">
        <property type="nucleotide sequence ID" value="XM_007691690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW21"/>
    <dbReference type="GeneID" id="19123478"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38486"/>
    <dbReference type="HOGENOM" id="CLU_2003495_0_0_1"/>
    <dbReference type="OrthoDB" id="3660474at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="124" mass="13538" checksum="9469894DE67EFA52" modified="2014-04-16" version="1">MENVFPDPVHQQIFSHLSPRRGELPIHVVETIAGNISFLVKYTAGYKVLPSQVSISVVDVRGPDNGLLGHKAMVCIHGAPGRFKVVVTKEVAYGRNVVIGLSEKVDRVVREIVSKEGNDGFGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW29</accession>
    <name>W6YW29_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_10234</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964266">
        <property type="protein sequence ID" value="EUC39729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693751.1">
        <property type="nucleotide sequence ID" value="XM_007695561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW29"/>
    <dbReference type="STRING" id="930090.W6YW29"/>
    <dbReference type="GeneID" id="19118061"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10234"/>
    <dbReference type="eggNOG" id="KOG4660">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_444140_0_0_1"/>
    <dbReference type="OrthoDB" id="417481at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007201">
        <property type="entry name" value="Mei2-like_Rrm_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04059">
        <property type="entry name" value="RRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="352"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="621"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC39729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="652" mass="73414" checksum="3772FE37F2C40B1B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX07</accession>
    <name>W6YX07_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_38197</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689568.1">
        <property type="nucleotide sequence ID" value="XM_007691378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX07"/>
    <dbReference type="STRING" id="930090.W6YX07"/>
    <dbReference type="GeneID" id="19123425"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38197"/>
    <dbReference type="eggNOG" id="KOG1991">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004196_0_0_1"/>
    <dbReference type="OrthoDB" id="760868at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000244">
        <property type="entry name" value="Nonsense-mediated mRNA decay protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF18">
        <property type="entry name" value="D-IMPORTIN 7_RANBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="24"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="904"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="909"/>
            <end position="933"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1044" mass="118901" checksum="48A38AD00E1B4758" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY84</accession>
    <name>W6YY84_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_7916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964058">
        <property type="protein sequence ID" value="EUC42538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690940.1">
        <property type="nucleotide sequence ID" value="XM_007692750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY84"/>
    <dbReference type="GeneID" id="19125434"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7916"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000051">
        <property type="entry name" value="Cytochrome P450 monooxygenase (Fum15)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF227">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
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    </dbReference>
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        <property type="entry name" value="Cytochrome P450"/>
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    </dbReference>
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    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="60129" checksum="A0EB0EB23717F8F4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY92</accession>
    <name>W6YY92_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_9603</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC40529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692940.1">
        <property type="nucleotide sequence ID" value="XM_007694750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY92"/>
    <dbReference type="GeneID" id="19128773"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9603"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000313">
        <property type="entry name" value="MFS quinate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF8">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="24"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC40529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="552" mass="61263" checksum="E5694E13DA97DD91" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYB8</accession>
    <name>W6YYB8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_103145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964056">
        <property type="protein sequence ID" value="EUC42568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692712.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19118233"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103145"/>
    <dbReference type="HOGENOM" id="CLU_203381_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="54" mass="6335" checksum="511A055AFC9CA7D8" modified="2014-04-16" version="1" fragment="single">EVALEYKLRVSLLSFINIALNYSLIYFSLDSIASILVVNYYRYLIYLDNILLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYH9</accession>
    <name>W6YYH9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_98364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689101.1">
        <property type="nucleotide sequence ID" value="XM_007690911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYH9"/>
    <dbReference type="GeneID" id="19129244"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98364"/>
    <dbReference type="eggNOG" id="ENOG502SPF6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_821692_0_0_1"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
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    <sequence length="322" mass="36806" checksum="AF5FA0C17FF65EB3" modified="2014-04-16" version="1">METWFVTLTAILLPLVVFVITIRRRQTQQREQKPFPFLELPRELRDMVYEYFLDDPVYPAPPRPSFHAPSVVSWMNLSRCISSTAPRPRLRNNKCIFLANKQVHAEYMDMLCKRCTFHFSVSPETYKSLPVTPLPSSPSPPPPTTAISTQEPTNVWNISPATLSKIRHCSLSLITTSAMLGVTDPRSMTSSSWSLGRRMRQQLKHMSSIQSFTLDAKALGDPLWNPLWIWYHASQSLKLLGTDLSDTVPRGPQLSRITFSLDTWSPGENYLERQAEGWTWYCARGHAVATDFGHDMTVREFCAKLYKECAACWAVAEEEDFL</sequence>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="9 10">Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.</text>
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</entry>
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        </source>
    </evidence>
    <sequence length="313" mass="33386" checksum="6D2EC0443A3D7D32" modified="2014-04-16" version="1">METRHTTRIHCAVHGRWCIRGGHQFAHDSVSGPNWGFSSVARLSYLGPCAGLVVGAGAAALCSPWPRSVACRRAAAQQQQRSVAYRSALQPVHPRPTPTPTPPPPLPSQHPQQQQTPLFHDHGQHKDHTPPPPSPRLAPAPCARRPPPTALSSFFVPLLLSAGQSPPPLLRRVHRPDTALALATGTQACSQEPTRAEPQNRSTLPIPFLSAREPSSACRGVVLSCPCLCCCLRPPATPADASPLFWACMCTLQGRLAVSHRPTSTSPKGKLPESNGPASVSPVPKSQGHTLCIPPVSPGFLHGNHALPLVRYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZS2</accession>
    <name>W6YZS2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ceramidase</fullName>
            <ecNumber evidence="1">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_107206</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.23" evidence="1"/>
    <dbReference type="EMBL" id="KI964123">
        <property type="protein sequence ID" value="EUC41044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692445.1">
        <property type="nucleotide sequence ID" value="XM_007694255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZS2"/>
    <dbReference type="GeneID" id="19119003"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107206"/>
    <dbReference type="eggNOG" id="ENOG502QVBG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051035_0_0_1"/>
    <dbReference type="OrthoDB" id="5273684at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017040">
        <property type="term" value="F:N-acylsphingosine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029130">
        <property type="entry name" value="Acid_ceramidase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28583">
        <property type="entry name" value="ACID AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28583:SF1">
        <property type="entry name" value="ACID CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15508">
        <property type="entry name" value="NAAA-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acid ceramidase N-terminal" evidence="3">
        <location>
            <begin position="5"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="462" mass="52575" checksum="0293BA34A3BDB569" modified="2014-04-16" version="1">MSVNSPPIYTIDLSLPPRSRYKAVAREYAPTLHQLTSLYTEVVAHLKLPPCFFHYLGRLLLRRLASNEQTEELRGISEECGVPMYLLVAYNVFLDLLLGCTSGGVLTKKPEQEGEGKGGEGDEEVTMMHFRTLDWSMPVLRDVIVQFDYINSPQGEVIARIVGYVGFVGILTGVRKGLSVSLNFRPYHNASGLSLENARYYWNTLLILLGRRPSITTVIRDFLLPRPKETPRVRRKLSKKRGRNGRKQQDLEEEKEELVPTYHPPHPPDAVTSLLPTLRTPVAYLIFCTPDETLILEKDFRTANILRSPTFLATTNHDIALEPHSPSQQPTTTSPVQPHIHAFLQSSIFQQASVQDILDDSIYRKECLTLAWRAWRRRRRQQEQQQERQQEAGREEEQSEMGVPLSTLERWVERWPVSNATTHFACIMDPGTGVFRWVRKFEAGEIVEPGVVGEGESVSGDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZS8</accession>
    <name>W6YZS8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_5891</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963996">
        <property type="protein sequence ID" value="EUC44847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688620.1">
        <property type="nucleotide sequence ID" value="XM_007690430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZS8"/>
    <dbReference type="STRING" id="930090.W6YZS8"/>
    <dbReference type="GeneID" id="19124768"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5891"/>
    <dbReference type="eggNOG" id="ENOG502QTAT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008220_0_0_1"/>
    <dbReference type="OrthoDB" id="38531at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057688">
        <property type="entry name" value="DUF7928"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408:SF3">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25550">
        <property type="entry name" value="DUF7928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="723"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="762"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="802"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="857"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="882"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7928" evidence="4">
        <location>
            <begin position="88"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="529"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="914" mass="102872" checksum="BA1D582FD1BB581A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZT9</accession>
    <name>W6YZT9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Palmitoyltransferase AKR1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 15">Ankyrin repeat-containing protein AKR1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Palmitoyltransferase akr1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_101707</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Palmitoyltransferase specific for casein kinase 1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Early endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690366.1">
        <property type="nucleotide sequence ID" value="XM_007692176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZT9"/>
    <dbReference type="STRING" id="930090.W6YZT9"/>
    <dbReference type="GeneID" id="19117915"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101707"/>
    <dbReference type="eggNOG" id="KOG0509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007182_0_0_1"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000397">
        <property type="entry name" value="ATP binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin_rpt"/>
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        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
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        <property type="entry name" value="ATPase_AFG1-like"/>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
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        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AFG1-LIKE ATPASE"/>
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    </dbReference>
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        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ANKYRIN"/>
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        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0564">Palmitate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="281"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="517"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="17">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
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    <feature type="repeat" description="ANK" evidence="17">
        <location>
            <begin position="99"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="17">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="17">
        <location>
            <begin position="198"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="20">
        <location>
            <begin position="418"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="573"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1090"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1175"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="580"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010104"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016875"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017919"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
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    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
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    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030960"/>
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    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031920"/>
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    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
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    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC43103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1195" mass="134028" checksum="AFFD5F4185B74BC6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZX0</accession>
    <name>W6YZX0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glycine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_101654</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 ATP + H(+) = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34935"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="4"/>
    <dbReference type="EMBL" id="KI964038">
        <property type="protein sequence ID" value="EUC43155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690344.1">
        <property type="nucleotide sequence ID" value="XM_007692154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZX0"/>
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    <dbReference type="GeneID" id="19117904"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101654"/>
    <dbReference type="eggNOG" id="KOG2298">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015515_1_0_1"/>
    <dbReference type="OrthoDB" id="57698at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070150">
        <property type="term" value="P:mitochondrial glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GlyRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="15">
        <location>
            <begin position="162"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00051967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC43155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="657" mass="74425" checksum="E51A302308B876F8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1D3</accession>
    <name>W6Z1D3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_8852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964102">
        <property type="protein sequence ID" value="EUC41459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1D3"/>
    <dbReference type="GeneID" id="19127286"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8852"/>
    <dbReference type="HOGENOM" id="CLU_1717553_0_0_1"/>
    <dbReference type="OrthoDB" id="10628536at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886355" evidence="2">
        <location>
            <begin position="23"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="153" mass="16851" checksum="ECD153CF0DB6139A" modified="2014-04-16" version="1" fragment="single">MKTMKRLLFVFFVLLLVSGVKAPLQKGYVVVREDIAQEAVTAIKMMVEEMAKIESNVRPVLPSWVMAAMLLSPLWLPVGIWLAARAVVLWDKTIRDALADPDRHGWFLRAILLVDRNLLWQSTREDGALAAAQVDAAAARAETAAARAETAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1L5</accession>
    <name>W6Z1L5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">D-arabinono-1,4-lactone oxidase</fullName>
            <shortName evidence="9">ALO</shortName>
            <ecNumber evidence="4 9">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_94913</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2 + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23756"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16292"/>
            <dbReference type="ChEBI" id="CHEBI:58277"/>
            <dbReference type="EC" id="1.1.3.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="4 9"/>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687838.1">
        <property type="nucleotide sequence ID" value="XM_007689648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1L5"/>
    <dbReference type="STRING" id="930090.W6Z1L5"/>
    <dbReference type="GeneID" id="19128541"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94913"/>
    <dbReference type="eggNOG" id="KOG4730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003896_4_1_1"/>
    <dbReference type="OrthoDB" id="610608at2759"/>
    <dbReference type="UniPathway" id="UPA00771">
        <property type="reaction ID" value="UER00766"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032473">
        <property type="term" value="C:cytoplasmic side of mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031489">
        <property type="term" value="F:myosin V binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070485">
        <property type="term" value="P:dehydro-D-arabinono-1,4-lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000001">
        <property type="term" value="P:mitochondrion inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030654">
        <property type="entry name" value="Sugar_lactone_oxidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01678">
        <property type="entry name" value="FAD_lactone_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="10">
        <location>
            <begin position="34"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="587" mass="67397" checksum="B6FAA1538ED2F07B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2J3</accession>
    <name>W6Z2J3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_27624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964015">
        <property type="protein sequence ID" value="EUC43943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689511.1">
        <property type="nucleotide sequence ID" value="XM_007691321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2J3"/>
    <dbReference type="GeneID" id="19121152"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27624"/>
    <dbReference type="HOGENOM" id="CLU_152666_0_0_1"/>
    <dbReference type="OrthoDB" id="3686613at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="140" mass="15213" checksum="E66C6EB3E9EE7FD9" modified="2014-04-16" version="1">MIKDRAPTFVMVGALLAILPIGLSILAACLHKRWRVRQRRKRDALAVSGEGLASGDAGKETAEGDRVQGSAAVMEKGQCFEGEQRSSSRDLVPESTTEIRVGSKIILLLCLPACALFVITIIICKLGIVFALLMMPEQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z317</accession>
    <name>W6Z317_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">feruloyl esterase</fullName>
            <ecNumber evidence="2">3.1.1.73</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_38008</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.1.73" evidence="2"/>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689361.1">
        <property type="nucleotide sequence ID" value="XM_007691171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z317"/>
    <dbReference type="GeneID" id="19123372"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38008"/>
    <dbReference type="eggNOG" id="ENOG502SD05">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027551_3_1_1"/>
    <dbReference type="OrthoDB" id="424610at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043595">
        <property type="entry name" value="FaeB/C/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050:SF2">
        <property type="entry name" value="FERULOYL ESTERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032964512" description="feruloyl esterase" evidence="10">
        <location>
            <begin position="17"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="314" mass="34470" checksum="690470C6939C87D3" modified="2014-04-16" version="1">MKLLLILSALATVLVADDSSGCDKPLPDGVLPGKSTSLTIDSESGITPRGYRLHIPESYEKNNPIPLIFSFHGRGKTAEYQEALSQFSNASYGFEGIAVYPEGVPNKKGTQQFQGDPDAPKSIDDVAFTLELLDHLETTYCIDTSRIYATGKSNGGGFTGILACDAEATKRIAAFAPVSGALYLDTNQQPPPCNPSRKPVPLMEFHGYRDHTIPYEGGINTRGNANSSDIVTYVNDWAQRNGYDALVNATTYLCDGEQKVMRHSWDDVVVHYNYTNIGHDWPSSFPNGDTDDLLTCEEAEATSIILEWFKKWTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z357</accession>
    <name>W6Z357_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="5">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_37744</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="5"/>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689076.1">
        <property type="nucleotide sequence ID" value="XM_007690886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z357"/>
    <dbReference type="GeneID" id="19123315"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37744"/>
    <dbReference type="eggNOG" id="ENOG502SM9C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_3_1_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF32">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887121" description="AA9 family lytic polysaccharide monooxygenase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="8">
        <location>
            <begin position="20"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="358"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="509" mass="53597" checksum="0A5D45F306057F59" modified="2014-04-16" version="1">MKTQSMLLAALASGPVALAHTVFTDIYVNGVPQGDGVAMRMSNDPPRSMYPISSLNSDDMACNVGGTKGVSRVQSVPDGATLTFEIRASPKDPSKGRLERGHKGPCAVYLKKVASAIEDKGAGDGWFKIFEHGYDSSSDSWCSDKVIDNNGLLNVKLPTGLEAGYYLARPELLALHNAKDGDPQFYTSCAQIFLESDGNLVPESTVSIPGYVDYGQPSTSFDLYNSDKSTYELPGPKLAKLTANSGQTGKSGQTTQTEGQKPAGCLAENANWCGVEVADYSDEKGCWASSKQCWQQSKKCFDTAPCTGNAGCKLWQTKCQGINDACKAGKFQGPPNKNKVLGQEKKKINVGAMLSGGIDSSYVDTTPKETPNKTSAAPTKAASAVPVAQKPVTTCSSSAAAAPTKVGDYSAPAIIDSDEDAAPSEPESGADAEAPKATPTQEASSYDAAPAPTAAPEVPSSEDGGSSCREGAVCVIVTEIETVVEYVTVTAEYRKRAAEHVARHRRARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z363</accession>
    <name>W6Z363_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_39808</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691382.1">
        <property type="nucleotide sequence ID" value="XM_007693192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z363"/>
    <dbReference type="STRING" id="930090.W6Z363"/>
    <dbReference type="GeneID" id="19123756"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39808"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_823835_0_0_1"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="212"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="357" mass="39987" checksum="BF7ED68B509D2B04" modified="2014-04-16" version="1">MLPQQVRLCLQALHISINEFSTFVASRGLDDDVVAAITEEGGSRLQDTLAQLRQLCELAEECMWPLKIHRIFLLNELPVANVLHEMRSPMQTAGSCNTVTLHEPLDMSQPIQEGRNPYQASPFESRSVDLERDKSFENLPVSILTRDLLRRGVHPIQLPRDPSLPPIGPIYLSDIPAGKPNPDLITAPPNSNTPRSASLNCVEPLDQFAHCKILIAEDNLINQRVMLKILGKLGMHNNVVVPDGQAAVDSVRELMGIYHPFDFIFMDESMPVLSGHEATRQIREMGFQGPICAMMVNTRLANKQRTWDSGATTIIQKPFMVSSVRNVLEQYLTPLIEEPIVDESPLPRRKPDIKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z462</accession>
    <name>W6Z462_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Uridylate kinase</fullName>
            <shortName evidence="9">UK</shortName>
            <ecNumber evidence="9">2.7.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:UMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Deoxycytidylate kinase</fullName>
            <shortName evidence="9">CK</shortName>
            <shortName evidence="9">dCMP kinase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Uridine monophosphate kinase</fullName>
            <shortName evidence="9">UMP kinase</shortName>
            <shortName evidence="9">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_27147</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UMP + ATP = UDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <text evidence="9">Predominantly cytoplasmic.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.14" evidence="9"/>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688927.1">
        <property type="nucleotide sequence ID" value="XM_007690737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z462"/>
    <dbReference type="STRING" id="930090.W6Z462"/>
    <dbReference type="GeneID" id="19121071"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27147"/>
    <dbReference type="eggNOG" id="KOG3079">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032354_0_0_1"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000315">
        <property type="entry name" value="Adenylate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03172">
        <property type="entry name" value="Adenylate_kinase_UMP_CMP_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006266">
        <property type="entry name" value="UMP_CMP_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01359">
        <property type="entry name" value="UMP_CMP_kin_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="9">
        <location>
            <begin position="148"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="9">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="128"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="176"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="209"/>
            <end position="212"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC44533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="315" mass="35162" checksum="81B9FA4227E7B468" modified="2014-04-16" version="1">MSWSLFRPRILFRQPQFLASRALSTSRPHASRLRQPGEPTGPNEPPAHISAPSSKSPLKVWPIVAIFATGTFLFKKIVDDRKGEGYQPKGPIQGHSPSGKGQTDIGARTSPLWSKDDVTVLFVLGGPGAGKGTQCQKLVNDYGFKHLSAGDLLREEQDREGSQFGEMIKTYIKEGTIVPMEVTVKLLENAMRSSMESGENDKKLFLIDGFPRKLDQAHAFERAVCPSKFTLFFECSEGVMEKRLLHRGETSGRADDNPESIRKRFRTFVETSMPVVNEFESQGRVVKVNAEQEPDAVYRDVQAKLKERGVEPISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4A1</accession>
    <name>W6Z4A1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate esterase family 3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_25412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686884.1">
        <property type="nucleotide sequence ID" value="XM_007688694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4A1"/>
    <dbReference type="STRING" id="930090.W6Z4A1"/>
    <dbReference type="GeneID" id="19120758"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25412"/>
    <dbReference type="eggNOG" id="ENOG502RG2M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044083_3_1_1"/>
    <dbReference type="OrthoDB" id="3915838at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF5">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="51"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="260" mass="28478" checksum="8C370732BFF11050" modified="2014-04-16" version="1">MISILGGPRHKTALRGVAVVGALCLLIALIVGLRHERPHANLHIPLRILPLGDSITWGWHPDSQQNGTDGYRAQLLRNLIRAWYQSVDFVGTQHSGFMFDNDNEGHVNSTIGEIMGAMTAALQMRPNVVLVHVGTTDLNRSDSALWKDAPQQLGRLLDAVLEACPDAVVLVAKIVQALNQRTSDNIRAFNEAVPEVVEERAKKGFKIRVVDQSVVSVYELVDGLHPSHAGYAHMGLIWSEAINDATEDALITPPIFNQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4M3</accession>
    <name>W6Z4M3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_96899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688543.1">
        <property type="nucleotide sequence ID" value="XM_007690353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4M3"/>
    <dbReference type="GeneID" id="19128939"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96899"/>
    <dbReference type="HOGENOM" id="CLU_2873712_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="64" mass="7285" checksum="0D78FFAE1C752ED3" modified="2014-04-16" version="1" fragment="single">LPPPPPTTNQKKKKINLSICFFSGILPIQTRINSRMNKFIRRKPVHLTPLPCPYPTPNLFAQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5E6</accession>
    <name>W6Z5E6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Intradiol ring-cleavage dioxygenases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_96796</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC44993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688495.1">
        <property type="nucleotide sequence ID" value="XM_007690305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5E6"/>
    <dbReference type="GeneID" id="19128920"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96796"/>
    <dbReference type="eggNOG" id="ENOG502QWDJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046727_2_0_1"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03461">
        <property type="entry name" value="1_2-HQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039390">
        <property type="entry name" value="1_2-HQD/HQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF7">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="8">
        <location>
            <begin position="36"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="7">
        <location>
            <begin position="116"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="36922" checksum="CA3D3A2E4FF882B7" modified="2014-04-16" version="1">MSLPKSADESTVPVLKNLTIENITENVHRINSQCSDPRLKYVMERLVTHLHDFARETRLSFDEWMAGIQFLTQVGQICTDVRQEFILLSDIVGLSLLVDSIDHPKPPSSTEGTVLGPFHTHDAPSSAPGANISADPSGTPLLVLCTVKTTSGAPISGVKIDVWETDSNGKYDVQYEDRGNKADGRAVITSDDEGVFWFKGIVPVPYPIPNDGPVGKLLDKLGRHCWRPSHMHFMFEKQGFDHLVTALYVRGSAYETSDAVFGVKDSLIVGLDTVTPQQAKQYDVAEGTKLLTYDFVLVTDEETKQLRHDEAVKAMKSLGREGMMIVNGLPVPEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5F9</accession>
    <name>W6Z5F9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_91356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
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            <end position="28"/>
        </location>
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            <begin position="546"/>
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            <begin position="1"/>
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        </location>
    </feature>
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            <begin position="153"/>
            <end position="168"/>
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            <begin position="171"/>
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            <begin position="562"/>
            <end position="571"/>
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    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="595" mass="65430" checksum="6A27A8ED06EC6165" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
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    </dbReference>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="12689" checksum="C3D33DE8BB76EE40" modified="2014-04-16" version="1">MSSVKGDSFQLYDLRVEMVCPAGERILCGAKEGDYFTVQGEMLHLPDGQGISFYSLAAVLPLLAAKQRSTHAHDWMSTDALIACPDPNCKSQLKITRTGLRTFSHADTTVVGLEGNS</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="19128660"/>
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    <dbReference type="eggNOG" id="ENOG502SCKV">
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    <dbReference type="OrthoDB" id="5193244at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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            <end position="20"/>
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            <begin position="21"/>
            <end position="100"/>
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    </feature>
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            <end position="86"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13396"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="100" mass="11176" checksum="3593BB62AB26FB9C" modified="2014-04-16" version="1">MFNLVLSLLLQLSMFMLAEAAPLTVQKAEPWQAGTGGGIVGFIVLVLDIIAWIEIFKSNRPVPNKVIWALVVFLFPVVGMIIYYLFSNRQAHNTYEPIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z637</accession>
    <name>W6Z637_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="5" type="ORF">COCMIDRAFT_5544</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
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    <dbReference type="STRING" id="930090.W6Z637"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_5544"/>
    <dbReference type="eggNOG" id="KOG0817">
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    <dbReference type="OrthoDB" id="346910at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF133">
        <property type="entry name" value="COA BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="ACB" evidence="4">
        <location>
            <begin position="5"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="119"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC45238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="398" mass="44855" checksum="EC530E632FAEB01C" modified="2014-04-16" version="1">MSDSVDRVFSHALNTVNKIRTGSQKPPSAIRLRLYGLYKQAMEGDVDGIMDCPRGNDDQSQRAREKWDAWKQQNGLSRTEAKRRYITTLIDTMHKYASPSPDSRELVAELEFVWDQVKSNVPSSSSSSPLRHSDHIQSGYSQHELGESRRAAMEMSAPLRRTDETPTREAVRDMPLRVKSPISQSEENLEEEEAEIDRGEVFVDAPDSQYNPTSYPDENDENDETNNLEDAGVQTDLQNLMRAEPIPIQTPTPAPKPRGMAVLGKPIQMPIPGFGSTPGPNNAAKESAADQKWRKRVEQSLMKMTAEVAALREQLEARRLFAHSAHYRLFRGIWRWVWACFKHVVVDAVVLGIVLLWMRRKKDKRLESTIREVLGDALAKLGRGGARIPFLGGGKKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z673</accession>
    <name>W6Z673_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_24857</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes. Involved in chromosome stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686241.1">
        <property type="nucleotide sequence ID" value="XM_007688051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z673"/>
    <dbReference type="STRING" id="930090.W6Z673"/>
    <dbReference type="GeneID" id="19120653"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24857"/>
    <dbReference type="eggNOG" id="KOG1757">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062828_2_1_1"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000791">
        <property type="term" value="C:euchromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140898">
        <property type="term" value="P:CENP-A eviction from euchromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070481">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, non-stop decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000021">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="22"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="13">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC47237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="144" mass="15288" checksum="4C7E1D1D1566562E" modified="2014-04-16" version="1">MAGGGKGKTGGKTGGKGDSQVKTPKSHSAKAGLQFPCGRIKRHLRNLTRQKTRIGAKASIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAFGGVLPHINRALLLKVEQKKKSGGAAKVGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6P6</accession>
    <name>W6Z6P6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_90249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686119.1">
        <property type="nucleotide sequence ID" value="XM_007687929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6P6"/>
    <dbReference type="STRING" id="930090.W6Z6P6"/>
    <dbReference type="GeneID" id="19127645"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90249"/>
    <dbReference type="eggNOG" id="ENOG502SJZG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_7_5_1"/>
    <dbReference type="OrthoDB" id="2504919at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="49"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="728" mass="82266" checksum="44323826EBB93027" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6S7</accession>
    <name>W6Z6S7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_90076</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Salamov A."/>
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                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
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                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <comment type="function">
        <text evidence="16">In the presence of oxygen and NADH, it has NADH oxidase activity, which leads to the generation of superoxide and H(2)O(2). Under anaerobic conditions, it also exhibits nitric oxide reductase and FAD reductase activities. However, all these reactions are much lower than NOD activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 nitric oxide + NADH + 2 O2 = 2 nitrate + NAD(+) + H(+)</text>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 nitric oxide + NADPH + 2 O2 = 2 nitrate + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="4"/>
    <dbReference type="EMBL" id="KI964020">
        <property type="protein sequence ID" value="EUC43744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689715.1">
        <property type="nucleotide sequence ID" value="XM_007691525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z856"/>
    <dbReference type="STRING" id="930090.W6Z856"/>
    <dbReference type="GeneID" id="19125097"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6839"/>
    <dbReference type="eggNOG" id="KOG3378">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_12_0_1"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase NAD(P)H activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071500">
        <property type="term" value="P:cellular response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046210">
        <property type="term" value="P:nitric oxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08922">
        <property type="entry name" value="FHb-globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06184">
        <property type="entry name" value="flavohem_like_fad_nad_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.490.10:FF:000003">
        <property type="entry name" value="Flavohemoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000034">
        <property type="entry name" value="Flavohemoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000010">
        <property type="entry name" value="Flavohemoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009805">
        <property type="entry name" value="PRK13289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0216">Detoxification</keyword>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin" evidence="17">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="18">
        <location>
            <begin position="150"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00056398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC43744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="426" mass="47167" checksum="DBBF439F068272F9" modified="2014-04-16" version="1">MATLTPTQVQIIKSTVPVLAEHGTAITTQFYHDMLQAHPELKNIFNNTHQATGHQAQALAGSLYAYAANIDNLGKLNPAVELICHKHASLFIRADQYSIVGQHLLSTMASVLGAAATPEILDAWGAAYWQLANLMISKETQLYRSTAYWPSWVDFRVAKKIRESEEITSFYLEPVDAAKLKLPRFRPGQYVSVRVFVEELDGGVWQARQYSLSDAPGKSYLRITVKREAGVVLGETKDMSHVGYISNLLHDAKHEGDVVQVSHPFGDFHLVDSGEAGHDDNSASPAVLISAGVGVTALMSMLNFLIDEEDSARPITWIQGARNSQTRAFKKHMDQCVANHGNVHAVYYLSRPSQEDMQGHDYDIKGRVDLDRVDRTILHTDNSSTVYYCCGPTSFMLDVEAQLKSYGVPSERVKMELFGTGGVPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8N8</accession>
    <name>W6Z8N8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone chaperone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_27657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8N8"/>
    <dbReference type="GeneID" id="19121160"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27657"/>
    <dbReference type="eggNOG" id="ENOG502S854">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139257_2_0_1"/>
    <dbReference type="OrthoDB" id="4357148at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="10725" checksum="DE10B0F0A550B468" modified="2014-04-16" version="1">MSSNEVPTGNAMDNSYQSRTGQSEIPVIKDEAPIESTEYDDGGDSDQQLERDEKEAIDRDNIISERTRGAAKQPGAYAEPVDDEGLGDAADGMDGTSSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA69</accession>
    <name>W6ZA69_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_98202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964004">
        <property type="protein sequence ID" value="EUC44434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689044.1">
        <property type="nucleotide sequence ID" value="XM_007690854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA69"/>
    <dbReference type="GeneID" id="19129206"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98202"/>
    <dbReference type="HOGENOM" id="CLU_135127_0_0_1"/>
    <dbReference type="OrthoDB" id="3683448at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="107" mass="12064" checksum="303FCFB216F4D76C" modified="2014-04-16" version="1" fragment="single">AKRRMPASLALDLASQHQATARNRDAHTQAYDENRPQPSAKRLLLRISFDLSALANLWGMTLRPQCSNSTKQIRLLSSPGGPRIRLKGPYRCRILHALCQYTIEPIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA86</accession>
    <name>W6ZA86_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_35774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686837.1">
        <property type="nucleotide sequence ID" value="XM_007688647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA86"/>
    <dbReference type="GeneID" id="19122864"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35774"/>
    <dbReference type="HOGENOM" id="CLU_1224654_0_0_1"/>
    <dbReference type="OrthoDB" id="3693607at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="271" mass="30612" checksum="73F0C2C0257C494C" modified="2014-04-16" version="1">MHGFPLISYYAFFPSLSGCHFPCYGITFYKLATYTQQQTSSSSNTLATDTAQGQTSNSAERFIAFPLSSASKKAYPTVFTLPHIGRELRPQEPIHARNLSRAESSITKNNNYSLYTDGSSVTSTNTDVNPEYSISTLLQKLTTFFINFFPRSHTTSVPNHPGTPSNHPHEPPFPPFLLPYTPAPSPYPSSLCSSSSESDKDPTRQKQKQKLKRKRCWVGRPRGAVLRPRDRYYARGLCDKHGNEVLFLENMRIHCGKKGEQGERWYAWRCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAC2</accession>
    <name>W6ZAC2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_92098</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686802.1">
        <property type="nucleotide sequence ID" value="XM_007688612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAC2"/>
    <dbReference type="STRING" id="930090.W6ZAC2"/>
    <dbReference type="GeneID" id="19128010"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92098"/>
    <dbReference type="eggNOG" id="KOG2169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004153_2_0_1"/>
    <dbReference type="OrthoDB" id="27975at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="6">
        <location>
            <begin position="882"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="229"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="554"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="628"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="994"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="562"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="587"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="638"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1044" mass="115428" checksum="960BF5811F7967BA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAH6</accession>
    <name>W6ZAH6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_91999</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the laat-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686741.1">
        <property type="nucleotide sequence ID" value="XM_007688551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAH6"/>
    <dbReference type="GeneID" id="19127987"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91999"/>
    <dbReference type="eggNOG" id="KOG2913">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019699_1_1_1"/>
    <dbReference type="OrthoDB" id="8048523at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098588">
        <property type="term" value="C:bounding membrane of organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015101">
        <property type="term" value="F:organic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034488">
        <property type="term" value="P:basic amino acid transmembrane export from vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034490">
        <property type="term" value="P:basic amino acid transmembrane import into vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000011">
        <property type="entry name" value="PQ loop repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF35">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER YPQ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="107"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC46798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="371" mass="41202" checksum="EA75ECC0C7BBAC4A" modified="2014-04-16" version="1">MFPPTQGLRLDIDAISQIFGSISIACWIVVFSPQIIENWKRSSAEGLSVVFIVIWLLGDFFNIIGAVLQGVLPTMIILAVYYTLADIVLLLQCFWYKGFTLRDNFKKPTSDSDEDSITSEQSPLLGERRPHSNGSPYNNQYGSGIEVQRPRISDYERRGSGNSQSSFRERYLSIDGTHLSPVTPLLDDPTSGRSTSAIATSPPPQQSNLQMIIFNAGTIILVCAAGVFGWYLSARNSTVPRDSDPPADSTLHFNLWGQISGYVCAALYLGSRVPQLLLNYRRKSTEGISMLFFLFACLGNLTYVLSILVYKPKCGGNVCHDGEGRAEYGKYIAVNMSWLLGSFGTLLLDAGVFVQYFMYRVDDEESSDDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAX2</accession>
    <name>W6ZAX2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_35271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686321.1">
        <property type="nucleotide sequence ID" value="XM_007688131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAX2"/>
    <dbReference type="GeneID" id="19122746"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35271"/>
    <dbReference type="eggNOG" id="ENOG502SASY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089396_0_0_1"/>
    <dbReference type="OrthoDB" id="5363415at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018858">
        <property type="entry name" value="DUF2458"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10454">
        <property type="entry name" value="DUF2458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="264" mass="29724" checksum="0BD1BAD92473627C" modified="2014-04-16" version="1">MAQDGQQNPDLAAILATLASLPKPEAQPYQEQQAYEQNHSYQGYQDPQQSYQHEQTHQYQPPPDPRLAGRPAPQHRQPPPKPQDRVSSPLIDPSTIIEWKQGLRCVSKIAAQNPDFAPAVRKLMKDQEANVKSWEAGRKKLIEEQKFQRENERTHRAALSLPGLLEGTALLRTPEREKEELDQYDAKVYRACKAMVDSQSSSLKVLGVPFFGVKPYLVLGASYDPMEVVDSSTVAVGGGGKITKERLLELQRKMLNHLMELYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAY3</accession>
    <name>W6ZAY3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_35408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC46968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686475.1">
        <property type="nucleotide sequence ID" value="XM_007688285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAY3"/>
    <dbReference type="GeneID" id="19122776"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35408"/>
    <dbReference type="HOGENOM" id="CLU_730666_0_0_1"/>
    <dbReference type="OrthoDB" id="3694693at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="418" mass="46762" checksum="C0ED19A477DDFDED" modified="2014-04-16" version="1">MSLLTRPPPPSTTNLLHRPNTFTVHFPTEATLHFTLPLPSSALSSLRTPELIHLRTYLTSLLSSHTLTSNPALLSHILSLRRTISLRLSRVQQLSAVEQKAWYSGHGFPIFDSENKATGFKWHWEALEFEYGVHSVAWVVRWLFAFQRKDATIRYALRQSYRFTENEVRCKKMKVEEGHEVVEWSCNGEKVCVWVYGACFRNMEEWEVVKMELEGYEVQMLKEGVAKIRNTVRGGWEFVLYVEGEEAGVEELFPGERTASEGFSSGSQDEDAESFDGYCYGDDVGRMVALASGLGSLALSSRASTACGGDEAVERAPTVPPRVGDLLQQAETLVSAIRGINSQFSSSEEQPSSSAQHSEIPPALQTQPLPPQYAASTIRLPRRTAARRPTKLHRYQAYAEDADTEGSISALPSSWRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBW2</accession>
    <name>W6ZBW2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_90077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686024.1">
        <property type="nucleotide sequence ID" value="XM_007687834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBW2"/>
    <dbReference type="GeneID" id="19127608"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90077"/>
    <dbReference type="HOGENOM" id="CLU_796947_0_0_1"/>
    <dbReference type="OrthoDB" id="3797449at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="320" mass="36237" checksum="802FC6C9BE155AB1" modified="2014-04-16" version="1">MSLTTLPSLPEPVLHLICIYLTPDRPSVNDPENGQSPTLYRPIISLSLTAHALNRISSTHIATNMSLTWGTIRWDLFLRTVLENPVYASTVKYLKLSELSLDEQDLVRPTKWQGGTDDLTEMFKALSGLQTLYSSHCRLLYPDSIIYRLTSQKMPLWKTLQVVRFDHINAWGEDRIAQLNLHRERTKDNEHGEPSKYTMGNGLLTGSLARLSILDFHKIPEVTNVVATTRDFEDDGDTEGDADWVDEDAEKEEGEDWSDDDDDYEYESEDSEWDSEDDSDYEDDWEAEYGFSVPSAQPVKEGLPTPAVGLSAPGKSLLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC37</accession>
    <name>W6ZC37_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">3-dehydrosphinganine reductase</fullName>
            <ecNumber evidence="14">1.1.1.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_89820</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22640"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57817"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.102"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:22642"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.102" evidence="14"/>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685936.1">
        <property type="nucleotide sequence ID" value="XM_007687746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC37"/>
    <dbReference type="STRING" id="930090.W6ZC37"/>
    <dbReference type="GeneID" id="19127554"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89820"/>
    <dbReference type="eggNOG" id="KOG1210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_3_0_1"/>
    <dbReference type="OrthoDB" id="10267115at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047560">
        <property type="term" value="F:3-dehydrosphinganine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006666">
        <property type="term" value="P:3-keto-sphinganine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08939">
        <property type="entry name" value="KDSR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000456">
        <property type="entry name" value="3-ketodihydrosphingosine reductase tsc10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045022">
        <property type="entry name" value="KDSR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550:SF3">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC47540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="366" mass="39528" checksum="0F3C50FA2B59FE7B" modified="2014-04-16" version="1">MLQFLAGAALVLIIGLVSFGIMGFSFSMSNRFPVDGKTVLLTGSSQGMGSEVACLLAARGANLILVARTAKNLEIAVQRAKSCAKNPSTQRFTYIVADVTSESENARILKEATAWNNGRVPEVVWCIAGSSTPGLFIETSTDTLRKQMELNYFATAYMAQKALQAWLYPEVPHSPQGKNTDPEAPRKFIMTSSSLAFINIAGYSPYSPAKAALRNLADGLRSEVQIYNAARHSNANTGATPAPFDVDIHIVFPGSILSPGFENENKTKHAVSFELEAADPKQTELEAATSCVKGLESGNFMTPTNYLVHLMRWGSLSGSQKNNWVIDAMGAIVAAIAWLFIAPDLNKTVRGWGKKNGMPAYRPNAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCN7</accession>
    <name>W6ZCN7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_33016</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683861.1">
        <property type="nucleotide sequence ID" value="XM_007685671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCN7"/>
    <dbReference type="STRING" id="930090.W6ZCN7"/>
    <dbReference type="GeneID" id="19122227"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33016"/>
    <dbReference type="eggNOG" id="KOG0478">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000995_7_0_1"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000217">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21128">
        <property type="entry name" value="WHD_MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="588"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="318"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="41"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
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        </source>
    </evidence>
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</entry>
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    <accession>W6ZD16</accession>
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            <fullName evidence="5">Peroxidase</fullName>
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        <name evidence="7" type="ORF">COCMIDRAFT_36911</name>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="4">Belongs to the peroxidase family.</text>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1 5" id="KW-0575">Peroxidase</keyword>
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        <location>
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    </feature>
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            <begin position="19"/>
            <end position="527"/>
        </location>
    </feature>
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        <location>
            <begin position="63"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC45334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="527" mass="56783" checksum="2DB54D786D7DB19F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDC5</accession>
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        </submittedName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687521.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408:SF2">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25550">
        <property type="entry name" value="DUF7928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="896"/>
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    </feature>
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        <location>
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            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
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            <end position="731"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25550"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDC7</accession>
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    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_88570</name>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963946">
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    <dbReference type="GeneID" id="19127300"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88570"/>
    <dbReference type="eggNOG" id="ENOG502SQZK">
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    </dbReference>
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    <dbReference type="OrthoDB" id="2117996at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889926" evidence="2">
        <location>
            <begin position="17"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="290" mass="28542" checksum="B04826B72190693C" modified="2014-04-16" version="1">MQYILVASLLTSAVYAAPYAQVQQQNPNARPATTPNNPTGQGAGIANGQTPTASDLATAVSNWMADTSMVSNFLNNGASIQNNVQFKQAATVAYNAEVDELNQKAVIDAANSADPNVIAANSTLATGGAFQDVVDKLQQMSIQGMAAAGNIDLINQNRCVNVLPNIDAYMASTGSSSQAVRPTACNQTGVINGVQGTGPTQPGAPAGSPAAAFAAAQALAQGTGNGLVQNGATPAAQGQAGAQGQAAQGQAGAQRPAGGAQGQAGAQGQAGAQGQAGAQGQAGAQRQAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE77</accession>
    <name>W6ZE77_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_36492</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687666.1">
        <property type="nucleotide sequence ID" value="XM_007689476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE77"/>
    <dbReference type="STRING" id="930090.W6ZE77"/>
    <dbReference type="GeneID" id="19123045"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36492"/>
    <dbReference type="eggNOG" id="KOG1336">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_4_2_1"/>
    <dbReference type="OrthoDB" id="6029at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03478">
        <property type="entry name" value="Rieske_AIFL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050446">
        <property type="entry name" value="FAD-oxidoreductase/Apoptosis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028202">
        <property type="entry name" value="Reductase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43557">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43557:SF2">
        <property type="entry name" value="RIESKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14759">
        <property type="entry name" value="Reductase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="10">
        <location>
            <begin position="7"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="549" mass="58864" checksum="8CE49F4C2B049468" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEB1</accession>
    <name>W6ZEB1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_94402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687632.1">
        <property type="nucleotide sequence ID" value="XM_007689442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEB1"/>
    <dbReference type="STRING" id="930090.W6ZEB1"/>
    <dbReference type="GeneID" id="19128442"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94402"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_425778_0_0_1"/>
    <dbReference type="OrthoDB" id="42889at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF137">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="125"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="643" mass="72149" checksum="3427FDFC67508CA4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZED1</accession>
    <name>W6ZED1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-ornithine N(5)-oxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_22274</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683265.1">
        <property type="nucleotide sequence ID" value="XM_007685075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZED1"/>
    <dbReference type="GeneID" id="19120218"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22274"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_7_0_1"/>
    <dbReference type="OrthoDB" id="3971593at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF10">
        <property type="entry name" value="L-ORNITHINE N(5)-OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="570"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="588" mass="67308" checksum="8703A208A68B6B2D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEJ7</accession>
    <name>W6ZEJ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_23847</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685116.1">
        <property type="nucleotide sequence ID" value="XM_007686926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEJ7"/>
    <dbReference type="GeneID" id="19120502"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23847"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="5141738at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000044">
        <property type="entry name" value="Hexose transporter Hxt3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF92">
        <property type="entry name" value="LOW AFFINITY GLUCOSE TRANSPORTER MSTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="408"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="57"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="570" mass="61967" checksum="AE2080EECAC96116" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEN7</accession>
    <name>W6ZEN7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_25947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687510.1">
        <property type="nucleotide sequence ID" value="XM_007689320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEN7"/>
    <dbReference type="GeneID" id="19120856"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25947"/>
    <dbReference type="HOGENOM" id="CLU_1570352_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="170" mass="19177" checksum="63AA3CBA9B3127FC" modified="2014-04-16" version="1">MARHGRMERISSSPPPPNPRGGIKQQVYSYRPYAWNIRIEFADIYPSGAYNVPYLISFLRPDTIFPLATCTHARLHMPRTSRLTCSYKNASFFSSAIGCWTSKTPSVIQERFSMHTFAIIVSVGVERLNVFSLLGPKGKTGRGTYLHRTSQFARLTPTNGLNSMTRVEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZES1</accession>
    <name>W6ZES1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_34240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685158.1">
        <property type="nucleotide sequence ID" value="XM_007686968.1"/>
    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049649_0_0_1"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="221"/>
            <end position="259"/>
        </location>
    </feature>
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        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="465" mass="51952" checksum="BDB60DF37801F69F" modified="2014-04-16" version="1">MAATLPGQAQSARQLYSYVLQPQLYSDHHHPDRQNTPEGPISIAFSKSSRRTIHTNNDLVKGVVHVKARLQIKRVTIKFIGKTTCRISNDRNPANPHCAEVELFCHEKTLSRIQTPTATCPPGRIEYPFEFRFPEKVEATPKLQNEAPFKPDALFEHETGHQLPPTLWCNENNICNEYFLRAEYVAEQTSFTLNPVVVHQLRFSPSVPELNIPSPLPLLPAPPIRFERKSRPSTPDPSKERRASLKRLASGLRNSSTEKLDDTSATSLLVLRAPAQYRVGAPSTLKISLQATLMNGGIDQHQQQPAAIHLRGIRAQVSAHITSRVPLASAPTGDARSQITEKFDLFNHRYVKPGIEITHDTTLDGLLVSTIVPPTFRTYAVALRYDVKYNLLLECAGKESEHEVEMRDVVIEPMTRPGGHLGPPEEPPPPLREGEMDVAREMMMMRQGGTNGVVGEQVPPPAYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF13</accession>
    <name>W6ZF13_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_87314</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685089.1">
        <property type="nucleotide sequence ID" value="XM_007686899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF13"/>
    <dbReference type="STRING" id="930090.W6ZF13"/>
    <dbReference type="GeneID" id="19127032"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87314"/>
    <dbReference type="eggNOG" id="KOG2997">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017706_0_0_1"/>
    <dbReference type="OrthoDB" id="2117972at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045464">
        <property type="entry name" value="Hrt3/FBXO9_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19270">
        <property type="entry name" value="FBO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
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        <location>
            <begin position="237"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="558" mass="62217" checksum="7C18E95421C74F50" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFD5</accession>
    <name>W6ZFD5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1690 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_104205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964070">
        <property type="protein sequence ID" value="EUC42176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691299.1">
        <property type="nucleotide sequence ID" value="XM_007693109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFD5"/>
    <dbReference type="GeneID" id="19118462"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104205"/>
    <dbReference type="eggNOG" id="ENOG502SDJV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093897_0_0_1"/>
    <dbReference type="OrthoDB" id="5544375at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012471">
        <property type="entry name" value="DUF1690"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07956">
        <property type="entry name" value="DUF1690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="21362" checksum="11F6D036ABEEA30D" modified="2014-04-16" version="1">MGAENSKPSSEVKQHVFSPDHPVSFSNELVGSLQKNPFTDSARSRQLELQYQERLTAELEKLRAQEIQNFNKISENLSDEIQQPSEPSLVEKIQDATSSSSTLAEKQRQRDMSRDSVTKEIERLKAKLEQRKKLEQADADVTKAKEAVVSCLRTHDRRPLDCWKEVEAFKHEVGRLEKEFVHKTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFF1</accession>
    <name>W6ZFF1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH psq-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_93499</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687320.1">
        <property type="nucleotide sequence ID" value="XM_007689130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFF1"/>
    <dbReference type="GeneID" id="19128278"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93499"/>
    <dbReference type="HOGENOM" id="CLU_3111889_0_0_1"/>
    <dbReference type="OrthoDB" id="5420958at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="56" mass="6381" checksum="E3032637AFEE9842" modified="2014-04-16" version="1" fragment="single">IDKASQALTRRVPPDVSKLYRALADHSGVPRATIHHHANSRRSIEEKALKQKYLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFX7</accession>
    <name>W6ZFX7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_80920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPI10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682718.1">
        <property type="nucleotide sequence ID" value="XM_007684528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFX7"/>
    <dbReference type="STRING" id="930090.W6ZFX7"/>
    <dbReference type="GeneID" id="19125766"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80920"/>
    <dbReference type="eggNOG" id="KOG4067">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084839_1_1_1"/>
    <dbReference type="OrthoDB" id="10248398at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048364">
        <property type="entry name" value="Hikeshi-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008493">
        <property type="entry name" value="Hikeshi-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031318">
        <property type="entry name" value="OPI10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925">
        <property type="entry name" value="HIKESHI FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925:SF0">
        <property type="entry name" value="PROTEIN HIKESHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21057">
        <property type="entry name" value="Hikeshi-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05603">
        <property type="entry name" value="Hikeshi-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hikeshi-like N-terminal" evidence="2">
        <location>
            <begin position="8"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Hikeshi-like C-terminal" evidence="3">
        <location>
            <begin position="162"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="216" mass="22557" checksum="CF07215381792127" modified="2014-04-16" version="1">MSSPVGIIISGRPVITEPSSIISPTQSAFQIPSQPSFSHIVVFLLPGVTLPDGTAAAVYAQLPGTTEFKLLGAIANEKPSAIFKVNTKAGSLGSDESMIDEGVSMGASNGNTTPLALGISVEPAQQVAAAIEQNKAQAAAGSQPTGAVQGNELVLRGQRSVETKVLAQRIIKNCYDFLTSWGTGDTVPLKAFQAWWTKFEGKIERDPGFLERGDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGA3</accession>
    <name>W6ZGA3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_23296</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684500.1">
        <property type="nucleotide sequence ID" value="XM_007686310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGA3"/>
    <dbReference type="GeneID" id="19120410"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23296"/>
    <dbReference type="eggNOG" id="ENOG502S4C9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110806_0_0_1"/>
    <dbReference type="OrthoDB" id="5563033at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009598">
        <property type="entry name" value="BCALP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13259">
        <property type="entry name" value="BLADDER CANCER 10 KD PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13259:SF1">
        <property type="entry name" value="BLADDER CANCER-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06726">
        <property type="entry name" value="BC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01396">
        <property type="entry name" value="BC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="140" mass="15452" checksum="B944F31AE27F8D7F" modified="2014-04-16" version="1">MFCLRSWIPVLFFLLRTQASPVYLVLFISATYFLNRPCVYCSLLLFILVVALFDFHTPWFDAPLSDSAELALNGTASETAGVLAQAANHTAQVVVKAAVEGVKGKIGLGQASDAQSYEWVKGLLGKKEWRIQCLDVLIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGE6</accession>
    <name>W6ZGE6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentatricopeptide repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_7860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964056">
        <property type="protein sequence ID" value="EUC42571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690890.1">
        <property type="nucleotide sequence ID" value="XM_007692700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGE6"/>
    <dbReference type="STRING" id="930090.W6ZGE6"/>
    <dbReference type="GeneID" id="19125413"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7860"/>
    <dbReference type="eggNOG" id="ENOG502S1QC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007655_0_1_1"/>
    <dbReference type="OrthoDB" id="5366531at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="884" mass="101823" checksum="AD666E2B7DBD3E71" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGG0</accession>
    <name>W6ZGG0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyltransferase family 34 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_80780</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682589.1">
        <property type="nucleotide sequence ID" value="XM_007684399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGG0"/>
    <dbReference type="STRING" id="930090.W6ZGG0"/>
    <dbReference type="GeneID" id="19125734"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80780"/>
    <dbReference type="eggNOG" id="KOG4748">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021434_0_0_1"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007114">
        <property type="term" value="P:cell budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000117">
        <property type="entry name" value="Glycosyltransferase family 34 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF5">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        <location>
            <begin position="431"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
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            <begin position="20"/>
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    </feature>
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        <location>
            <begin position="445"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="456" mass="53476" checksum="E4022D09000DD70D" modified="2014-04-16" version="1">MSRSSSPQPGGWSSPGLNTPYDNSGQSSPYPNGSSSHNVTWASAQARSAEVKGYPAFTPRGQGFFGKHFRKISMSLPFNHGDKEKLGRGRSQGNKVTRALNGIVWNLWRLRKRVMILFLVTFLLFFWNFNTPIRRAYRRSAWFGGGSKYVVILAANQGGGVMEWKGPREWAIERDSVKNKKKYTRNWGYELEIVDMSTKKRYAHEWRESWEKVDTIRNAMRKYPHAEWFWWLDTNTFIMEPTYSLQKHIFKQLQDVTYRDINVYNPLNITHPLTDDYLDPETRSPVGDGRVDSVNMLVPQDCGGFNLGSFMVRRSVWTDRLLDIWWDPVGYEQKHMQWEHKEQDAFEHMYQNQPWIRPHVAFIQQRQIMSFPPGACGEQGDNPDIHYQEKDRDFLVNMAGCEWGRDCWAEMYKYRELSNHLNRTPWEKFKDGLSGLFKSKPKKDGKKDGKKEEKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGM8</accession>
    <name>W6ZGM8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_23143</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC49160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007686097.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_23143"/>
    <dbReference type="eggNOG" id="KOG0065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_35_0_1"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002416">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="625"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="658"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="700"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="732"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="765"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="870"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1298"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1331"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1369"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1409"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1440"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1567"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="262"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="963"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="67"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="918"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1601"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="918"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1601"/>
            <end position="1611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC49160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1620" mass="180300" checksum="E311AFCF6AC56B0F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH53</accession>
    <name>W6ZH53_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Multidrug resistance-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_7596</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964046">
        <property type="protein sequence ID" value="EUC42871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690584.1">
        <property type="nucleotide sequence ID" value="XM_007692394.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZH53"/>
    <dbReference type="GeneID" id="19125327"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7596"/>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_27_6_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042592">
        <property type="term" value="P:homeostatic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18595">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000020">
        <property type="entry name" value="ABC metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000450">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000001">
        <property type="entry name" value="ATP-binding cassette subfamily C member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="526"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="559"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="969"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1013"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1112"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1197"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="16">
        <location>
            <begin position="302"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="622"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="16">
        <location>
            <begin position="974"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="1294"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="847"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="880"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="911"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC42871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1543" mass="171839" checksum="3C4F7EEC31595B7E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH55</accession>
    <name>W6ZH55_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_7601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964046">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692395.1"/>
    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_041445_0_0_1"/>
    <dbReference type="OrthoDB" id="3205825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="99"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
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        <location>
            <begin position="250"/>
            <end position="297"/>
        </location>
    </feature>
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        <location>
            <begin position="318"/>
            <end position="367"/>
        </location>
    </feature>
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        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="367" mass="41419" checksum="8E1C1835EBB07B72" modified="2014-04-16" version="1">MASVQDFQLAALAAGFTLGFGFLTVWEAIKQTRRNHSPLRSAYIYMVWGEIVVNIGIGVIGWLFLNGTVGPSVPVLFSILFFWVFEIQLLMQIIINRIALIAEHRSTIKKLKWGTFIFITAINIAVFCIWIPSHTSPPLHETFVKINNVWDKISKLLILIVDAALNWYFLRTVKIRLVNQHGLTKYAPLISFNGKLMLISIAMDALLIGLMFLRNQVVYIQFHPVAYMVKLNIEMSMASLVVRLAQGKSQNDMGPEEFHSTTDPESHSRSAAAAQSLHLTNRSKRNNPSNMRSAGLSKIDSDESLDFGGIQCHTELRITHEDRKDTTDKRDFVESSSRSSNDAPALSVFGDETPLHKKTFRVQEKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHJ8</accession>
    <name>W6ZHJ8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_84457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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                <person name="Turgeon B.G."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578">
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    </dbReference>
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            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="277" mass="30088" checksum="38FFF0F273EC9426" modified="2014-04-16" version="1">MANHLKEKSLYSELHAASIGVGIPTPTAVSVAVTPQMSPESTGPAHTPIVTRGTYGDCEAQPSGYGPIPKYDNMRGFYYSPEIRHAADNAPIPPGYIKSFVSANGSFVGSHYLGHYELKSFDTLECARRCNEWGKLANPPSDGPSSNESNTRDASPIVATSYRDPDTRGTEPGHDQLCQGFNTYFERAPAIRLGPECRESTSRTVIKCALWGEPLRIEGAKNIGYREWDFDVVIAGSNGYSSEKYAELSNLAPGKKLEPVVLAALFAPQVFLGFMAF</sequence>
</entry>
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    <name>W6ZHU0_COCMI</name>
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        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
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    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_91285</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
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        <property type="protein sequence ID" value="EUC46974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007688308.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_91285"/>
    <dbReference type="eggNOG" id="KOG0254">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF189">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="36"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="534"/>
            <end position="553"/>
        </location>
    </feature>
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        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="534"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC46974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="553" mass="59887" checksum="56AA3F9555AE850A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI12</accession>
    <name>W6ZI12_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_84316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI12"/>
    <dbReference type="GeneID" id="19126440"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84316"/>
    <dbReference type="HOGENOM" id="CLU_1137828_0_0_1"/>
    <dbReference type="OrthoDB" id="3690794at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="32717" checksum="7F1E88F06DAF6FB4" modified="2014-04-16" version="1">MERIAYFHSAHTEPIMSASALWPSGHPNLLQRGSQSSSQSEEMRILNHPQTSSFNRLPTELILKICGHISAHDLWHNIRPTSRLLAICAREVLPRKVFSESNIHISWCCFWCSLGRHCLHTACNPITWLFPDAKNVSVALISDRATVAKVIFGDLCNLVTSYEPKIRIRLGEEAQGVRCRSKAIRPRIRPHTANSDSDLQSRQEEFVMWYFATQRRQRARGRILRCLEFAAHLLRFFTTSAVLLSVGLILTLAVYAILEICKLGMCCYRSGKNFMRFCMGKFPLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIU7</accession>
    <name>W6ZIU7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Iron reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_65326</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Bushley K.E."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Grimwood J."/>
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        <source>
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<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMC7</accession>
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        <recommendedName>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688752.1">
        <property type="nucleotide sequence ID" value="XM_007690562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMC7"/>
    <dbReference type="STRING" id="930090.W6ZMC7"/>
    <dbReference type="GeneID" id="19129072"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97489"/>
    <dbReference type="eggNOG" id="KOG1940">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143932_0_0_1"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045041">
        <property type="term" value="P:protein import into mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052604">
        <property type="entry name" value="Mito_Tim_assembly_helper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016694">
        <property type="entry name" value="UCP017292"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082:SF1">
        <property type="entry name" value="HELPER OF TIM PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017292">
        <property type="entry name" value="UCP017292_Znf_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="5">
        <location>
            <begin position="17"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC44741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="119" mass="13240" checksum="050F4FA599F70DF3" modified="2014-04-16" version="1">MSEPTANDGDPAVYGLSVTPLTQCAHWHSPLDIIAIKHFCCKKFYACISCHDALETHTSDIWPQTQRNESAVLCGQCKHVLTVDEYLKSGSKCTRCTSKFNPGCKNHWGLYFQLDGSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMI2</accession>
    <name>W6ZMI2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Endoplasmic oxidoreductin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_2402</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684686.1">
        <property type="nucleotide sequence ID" value="XM_007686496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMI2"/>
    <dbReference type="STRING" id="930090.W6ZMI2"/>
    <dbReference type="GeneID" id="19120530"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2402"/>
    <dbReference type="eggNOG" id="KOG2608">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023061_1_0_1"/>
    <dbReference type="OrthoDB" id="269384at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017205">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 17" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 20" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887210" description="Endoplasmic oxidoreductin" evidence="20">
        <location>
            <begin position="22"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="450"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="121"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="450"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC48739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="23">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="637" mass="71718" checksum="7822FF012F446C6E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNU1</accession>
    <name>W6ZNU1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Selenoprotein O</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_96039</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SELO family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688258.1">
        <property type="nucleotide sequence ID" value="XM_007690068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNU1"/>
    <dbReference type="STRING" id="930090.W6ZNU1"/>
    <dbReference type="GeneID" id="19128774"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96039"/>
    <dbReference type="eggNOG" id="KOG2542">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010245_2_1_1"/>
    <dbReference type="OrthoDB" id="10254721at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070733">
        <property type="term" value="F:AMPylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057:SF14">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="622" mass="70627" checksum="31ADC57A8BC284DF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNX4</accession>
    <name>W6ZNX4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_95911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688208.1">
        <property type="nucleotide sequence ID" value="XM_007690018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNX4"/>
    <dbReference type="GeneID" id="19128749"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95911"/>
    <dbReference type="HOGENOM" id="CLU_198480_0_0_1"/>
    <dbReference type="OrthoDB" id="10297224at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="52" mass="6055" checksum="0DBFC88558F18263" modified="2014-04-16" version="1">MHICDVKRKNFEESMDLVTFHVCLSNLLHSEKEGGCSRQATPLSCIRHLFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPA6</accession>
    <name>W6ZPA6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Polyprenal reductase</fullName>
            <ecNumber evidence="5">1.3.1.94</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_84729</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol. Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a di-trans,poly-cis-dolichal + NADP(+) = a di-trans,poly-cis-polyprenal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:80727"/>
            <dbReference type="Rhea" id="RHEA-COMP:19536"/>
            <dbReference type="Rhea" id="RHEA-COMP:19537"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:231623"/>
            <dbReference type="ChEBI" id="CHEBI:231637"/>
            <dbReference type="EC" id="1.3.1.94"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:80729"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the steroid 5-alpha reductase family. Polyprenal reductase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.94" evidence="5"/>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684092.1">
        <property type="nucleotide sequence ID" value="XM_007685902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPA6"/>
    <dbReference type="STRING" id="930090.W6ZPA6"/>
    <dbReference type="GeneID" id="19126520"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84729"/>
    <dbReference type="eggNOG" id="KOG1640">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044409_0_1_1"/>
    <dbReference type="OrthoDB" id="541710at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160198">
        <property type="term" value="F:polyprenal reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102389">
        <property type="term" value="F:polyprenol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016095">
        <property type="term" value="P:polyprenol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039698">
        <property type="entry name" value="Dfg10/SRD5A3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624">
        <property type="entry name" value="DFG10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624:SF0">
        <property type="entry name" value="POLYPRENOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="167"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC49334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="282" mass="31605" checksum="F14DC1ECB1BE62B2" modified="2014-04-16" version="1">MALLQSSLMPVLLRAFYLAASVLILVIQAVPALRTRFLAYGPRATTPPTQETQEHQKHHQQPSALSRALDYAASLQVPHHFFTHFYVTSVACSLLWAWQMDVWHAHRQQQVVWALLLLQGLRRVLESHVYTSASKSTMSVAHWLLGLLFYITINAAIWVETPGSASANAFLVPGVITAQMLQHSYHAYLYRLRTENKGYQLPSHPMFPNLLCPHYTCEVVIYALLSLITAPDGSLVNWTVACGTIFVATNLGVTAVGTKEWYMAKFGADKVGSRKRMVPAMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ94</accession>
    <name>W6ZQ94_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_32887</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC49659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683753.1">
        <property type="nucleotide sequence ID" value="XM_007685563.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19122199"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32887"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF12">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887022" description="Cytochrome P450" evidence="7">
        <location>
            <begin position="20"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="57339" checksum="42DDE709ECB80D81" modified="2014-04-16" version="1">MTSLMILVVTLAGLAFAVAIRKYVRSRKYKLPPRVPGLPIVGNTFQFRLDPVKQGPWAAKIAIEYGEMFTIRVGGCDMVFLNSSRVVRELMDKRSSKYSSRAEMPMVSDTMSGGNCIVLMPYNERWRSIRKVMHSVLNSRNMAQFSTYQEIESRQLLWDYLYNPGAWFTHNQRFANSVIVSVVFGRRIPLGDPNLGPLLRQAEAMVEHLQPGATLVDGFPILAKLPKSLQWWRKRGEALYKESLRVYGYELDKIQEKINAGKAPECFAREFLQSPDAAKMEESQRIFTLGSLLEAGSDTSRMTLSQTVAAMAIFPEWVSIARGHLDKVCGDAGRLPRWEDKPQLRYISAAVKESFRWRPFAPIGVPYQISVDDEFEGYHFPAGTQITWNSLYISQNEDEYKNAKVFDPARFLNDDLDSVTKGHWAFGPGRRACPGYNVAERNVWMAISRLIYCFDFTTVPGHEIDPVNANWKDYRVAPFKVSITPRSAAHKELILETCADIAGEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZS06</accession>
    <name>W6ZS06_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_32378</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683161.1">
        <property type="nucleotide sequence ID" value="XM_007684971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZS06"/>
    <dbReference type="GeneID" id="19122090"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32378"/>
    <dbReference type="eggNOG" id="ENOG502SHVM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1023044_0_0_1"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="85"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="272" mass="30700" checksum="012C9DA5CC9BE0E0" modified="2014-04-16" version="1">MQLADPAQSYSFIQSNPFLKGITLRMTWHINFSRVKLVRVVGWDNLFVLLSLLCSIIALSSVRYGAVLGFGQHTAVIVAQFGNQRLFKGALIRILGYPSFAVITIALAFTQCRPTQKLWEKSLPGSCWNPNILNSFSYWFCAYTTFTDVVLTVAPACTFWNLQIAWSTKIGLIVMMIWKPVALIIWGLVEQNIVIMAACVPTMRPFFRRTWRCNFSTKPGARSRFLAQDPFTYTKGTRSPLKCQSGSISDVALTHFELHGDRFDQMVHGGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSL7</accession>
    <name>W6ZSL7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_32325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683043.1">
        <property type="nucleotide sequence ID" value="XM_007684853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSL7"/>
    <dbReference type="STRING" id="930090.W6ZSL7"/>
    <dbReference type="GeneID" id="19122077"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32325"/>
    <dbReference type="eggNOG" id="KOG2890">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043563_1_0_1"/>
    <dbReference type="OrthoDB" id="73612at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1540.10:FF:000004">
        <property type="entry name" value="Transmembrane protein 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013861">
        <property type="entry name" value="TMEM115/Pdh1/Rbl19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13377">
        <property type="entry name" value="PLACENTAL PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13377:SF3">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08551">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01160">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="329"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="370" mass="40184" checksum="17F1184528F1EAA8" modified="2014-04-16" version="1">MARINLPPLTRGILAALILLTLLNFGLRPNANWVEKVEKPIIGVGNGVPWLTIVPRLSVPWYPWTFALATVVEQNLLGLITTGLTVFYGGRYLERAWGSHEFTKFMLFVAVIPNLLTYLLYVLGYLLMRKGFLMKTTISGGIAIQAGFLVSFKQLVPEHTVAIAKGLIRMRVKHFPAIFLLTNTLSGIIIGTETAMYLAYFGFMTAWIYLRFYRISPSLSSTATGEGSFIRGDASDTFSFAHFFPEPIQTPLGAFADGVYNTLVSLQVCTPFSDRDIDAGNEQATARAEGGLPSIMNPNSRGGRGGATRAEAERRRALALEALNQRLNAAASRGPSAAAPAAVSVSGPSQSLGETNYEPDRPDVSEKSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU07</accession>
    <name>W6ZU07_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_35316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686331.1">
        <property type="nucleotide sequence ID" value="XM_007688141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZU07"/>
    <dbReference type="STRING" id="930090.W6ZU07"/>
    <dbReference type="GeneID" id="19122756"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35316"/>
    <dbReference type="eggNOG" id="ENOG502STHF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041685_0_0_1"/>
    <dbReference type="OrthoDB" id="5295250at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="49"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="506" mass="57113" checksum="6EA2DA80866400E9" modified="2014-04-16" version="1">MVIMADFVQTFARFNHAQRQHALALLTAELTPYEWRYLHALTSSRSFQLDIIGRLPIELVAHVFTHLDPAAPYRFQVVSTRWRHILQSLPVLNAGLNSWYQGAVNPRDLENDTARQRAARRVHCFRTGRPLGIYKITSDEQIARPSMLGDYLGWLSETPQASPMRVACIFNLHNWNLDHIAGEAREQLINLVLSDQIVVLVTAADACYVFELPTLSQRKKFRVPSASYLQNVTCRRSTVACLASLDMRTSVYIWDYNTQRGTSFTISHDSDMFLGTHGPRGLLHIAPLLQPESETITLMFVMDTPTETPSQTLFVCARYTFGGNCVSSFSPSLPELRPLLVWHGITPFVPVDDSANVFAARVNARNPGSQPSNASMASLLLRFDTKTNDLRVWEGPIHRSNSPHGINDYLSSWWKDTWYGFHPSVETRDIITYMGTQDKPACTPIFQDPDSEVTGGDIHTGPMFVNEKYVVRAMSESIYVLCFDESSVQPRTGSTFFMNGTIRLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUK9</accession>
    <name>W6ZUK9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_35010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686001.1">
        <property type="nucleotide sequence ID" value="XM_007687811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUK9"/>
    <dbReference type="STRING" id="930090.W6ZUK9"/>
    <dbReference type="GeneID" id="19122685"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35010"/>
    <dbReference type="eggNOG" id="KOG0016">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_6_2_1"/>
    <dbReference type="OrthoDB" id="448450at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000048">
        <property type="entry name" value="3,2-trans-enoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="30542" checksum="42EEF8A29068AD0F" modified="2014-04-16" version="1">MSDAPEAPDSWITVEYLGRLAILIINRPHKLGALTKDGFYLLTQRLREIDTHDEVFITILTGTGRFFSAGVDVSTSRPVEPGTDIWRDSLRETVSHTLNSTEAFYTHSKILVTALNGPVVGIAAALISFSDFIFCAPHTYLLTPFTSLGLIAEGGASVGFVRRMGVTRATEALLTSRKILADDLLACGFVNKIFEDCGEGEDEKLRERVIAHVDEILGEHLVGSSLLETKKFLLMGMKGQIDQSLVAELMGGLKRQVLGIPQREFEKIRTGEKRHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVB6</accession>
    <name>W6ZVB6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_70249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685783.1">
        <property type="nucleotide sequence ID" value="XM_007687593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZVB6"/>
    <dbReference type="GeneID" id="19125154"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_70249"/>
    <dbReference type="eggNOG" id="ENOG502R92F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816546_0_0_1"/>
    <dbReference type="OrthoDB" id="3800892at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="312" mass="34710" checksum="5CDEE06146FD6F8E" modified="2014-04-16" version="1" fragment="single">MAGGDNAIKCKSCTRVLAAVTADGLTPVQAPDEFGCSTCQRFGTLYDALQAADTEWAAFENKRDSITKSFARDKHKKARMEFDNWLMTVEALPVPPTRECTTRIKEASPEVQYVFHGSEEPHLGITRRRSHSPTTQPPVTAEESPNPRLQQCDAPLSFRPSPKRSRSTNSLLGRKRLKFSDTVEFHKTYRSSDEYHRPSQLYVRGRNAPPEGSEYMDTSGSSQTFLRFTQMKKVGAKWVELSEEDLARKSKSPALAVTQQAQPAAEQLKSQSRNEDVAGKLEQEGEAPPDARAARLARRAKEASSMGSSQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX88</accession>
    <name>W6ZX88_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_87510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:12706"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="10"/>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685084.1">
        <property type="nucleotide sequence ID" value="XM_007686894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX88"/>
    <dbReference type="STRING" id="930090.W6ZX88"/>
    <dbReference type="GeneID" id="19127082"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87510"/>
    <dbReference type="eggNOG" id="KOG1661">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055432_0_4_1"/>
    <dbReference type="OrthoDB" id="73890at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000235">
        <property type="entry name" value="Protein-L-isoaspartate O-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00054057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="222" mass="23853" checksum="68297C69C4B3766F" modified="2014-04-16" version="1">MAWRSSGDTNEALVTNLASNKLIKSDRVKDAMLKVDRAHYAPSSPYEDSPQPIGHRATISAPHMHASACESLLDYLKPGSKVLDVGSGSGYLTAVLANLVVPNGTVIGIDHIQPLNDLAIANMSKSDQGRRMLESGQVKFVTGDGRKGWAEGAPYDAIHVGAAAAEHHQVLTDQLKAPGRLFVPVAEGWAQHIWVIDKRADGSLERQKLYGVQYVPLTDAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0L4</accession>
    <name>W7A0L4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_84220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683889.1">
        <property type="nucleotide sequence ID" value="XM_007685699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0L4"/>
    <dbReference type="STRING" id="930090.W7A0L4"/>
    <dbReference type="GeneID" id="19126423"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84220"/>
    <dbReference type="eggNOG" id="ENOG502S3QT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023133_0_0_1"/>
    <dbReference type="OrthoDB" id="5590473at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18724">
        <property type="entry name" value="PIN_LabA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007681">
        <property type="entry name" value="Mog1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837:SF5">
        <property type="entry name" value="NYN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="501"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="68603" checksum="A75DC983F2A2F144" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1L8</accession>
    <name>W7A1L8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_32716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683529.1">
        <property type="nucleotide sequence ID" value="XM_007685339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A1L8"/>
    <dbReference type="STRING" id="930090.W7A1L8"/>
    <dbReference type="GeneID" id="19122168"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32716"/>
    <dbReference type="eggNOG" id="ENOG502QRYC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1053708_0_0_1"/>
    <dbReference type="OrthoDB" id="5406216at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="264" mass="27288" checksum="FC7B6E7A2E54DF1A" modified="2014-04-16" version="1">MMQSVTKGYGFQNARSYHLNTSAAGFDCMHAPSGVWASARCGDYTHGRSKSDIHPSSSSDSDSRTIQLWYRIYQAPAVASAEDAPAQGLVVGVPTLPFASTPTVEPAIIVPVNTTAGSSLGDASVARVEPADVVPPPSIANHAVNPVPPAPAPTSSASSSMESSSVTHATTSFGNVPFVTVQWVETFIGGTYSTWWPHTISLDFKPQRSVAPAPGRGEIGMGTLTGKTGQTQTVVEVVAAAPTQDSGWAKGVAAMVGVGIMGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJQ8</accession>
    <name>W6YJQ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_41895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964309">
        <property type="protein sequence ID" value="EUC39607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693873.1">
        <property type="nucleotide sequence ID" value="XM_007695683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YJQ8"/>
    <dbReference type="GeneID" id="19124150"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41895"/>
    <dbReference type="eggNOG" id="ENOG502S6FA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033740_0_0_1"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="346" mass="38724" checksum="190E07EB47611756" modified="2014-04-16" version="1">MQLIGELFCPLSLRLIVTNIPAIELIAKITLRIADPFEYFCGRTYTYAIDLEEHRRARGHFPSHVCRGSCRHPLVAQYDFTIRKCGYCGKLYKRLDIFKDHYIATRHYFCNARKAGKATTVSAGDHVYKICRRTFPSLQSFQQHCKSIKHKPISALSCPIGGGCKRKFSAPSALLHHLESGKCCSGMDRDDIYDIVQLYDKDHTIHTLPKLTPSSSTYLSLHGLSPGSGTPTASLDSPDGWLLVTPTHSQAFRTIQALQQHIVSPTHYNKVYHCPRNPLPINSSKAKTKQEKAKQFTTLSGLAQHLESGAYLGGRQTFLRCIELIQQHLGQCGLRGMSLLLPGSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPD6</accession>
    <name>W6YPD6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_9048</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964114">
        <property type="protein sequence ID" value="EUC41222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692264.1">
        <property type="nucleotide sequence ID" value="XM_007694074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPD6"/>
    <dbReference type="STRING" id="930090.W6YPD6"/>
    <dbReference type="GeneID" id="19127692"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9048"/>
    <dbReference type="eggNOG" id="KOG2767">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026663_1_0_1"/>
    <dbReference type="OrthoDB" id="10250831at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045947">
        <property type="term" value="P:negative regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000031">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.350:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="7">
        <location>
            <begin position="252"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="415" mass="46341" checksum="674FAE6B9B05EAF2" modified="2014-04-16" version="1">MATVNIRRDVTDPFYRYKMERIQSKIEGKGNGIKTVIVNLTSVAGSLARPPAHVIKYFGFELGAQTNTSPNDDRWIINGAHDASKLQDYLDGFISKFVLCKKCKNPETDVHIKDGNITLDCKACGKISEVDPRLKLSSFILKNEPKKGKKDKSSKKAERRARKEAEARGEAGSPDNGSPGDSAEENGDDGDLALEAGSDDELTRQINEGAKEIEEEDAKEVEWSIDTSEAAIRARAQDLPDDLKRALVIEEDEEGGSSYDTFGKWIIDTGAEKGGVENLDNVDIYIKAKELGIETKHRTLTVIPQTLFTEKIVKQIDARAPMLKKMITSDKHEKAFLGGIERFVGIEKPELIPQVSAILLKVYENDLVSEEQLQTWCSKASKRYVDLKVSKTVRKSAEQFKNWLEQEESEEEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ02</accession>
    <name>W6YQ02_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964279">
        <property type="protein sequence ID" value="EUC39685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693794.1">
        <property type="nucleotide sequence ID" value="XM_007695604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ02"/>
    <dbReference type="GeneID" id="19119677"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110839"/>
    <dbReference type="HOGENOM" id="CLU_2891896_0_0_1"/>
    <dbReference type="OrthoDB" id="10347025at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="63" mass="7287" checksum="4A19B0108C0C1FEB" modified="2014-04-16" version="1" fragment="single">LLPSDVDVHRPSAISLFVKERILLVTCNTCYHIECRRIASVIWERTLVIEVRISYLCVSEKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ75</accession>
    <name>W6YQ75_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dynamin GTPase</fullName>
            <ecNumber evidence="3">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">COCMIDRAFT_10210</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="3"/>
    <dbReference type="EMBL" id="KI964258">
        <property type="protein sequence ID" value="EUC39765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693716.1">
        <property type="nucleotide sequence ID" value="XM_007695526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ75"/>
    <dbReference type="STRING" id="930090.W6YQ75"/>
    <dbReference type="GeneID" id="19118008"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10210"/>
    <dbReference type="eggNOG" id="KOG0446">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008640_0_0_1"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030061">
        <property type="term" value="C:mitochondrial crista"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097002">
        <property type="term" value="C:mitochondrial inner boundary membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901612">
        <property type="term" value="F:cardiolipin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140523">
        <property type="term" value="F:GTPase-dependent fusogenic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180020">
        <property type="term" value="F:membrane bending activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070300">
        <property type="term" value="F:phosphatidic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080025">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015886">
        <property type="term" value="P:heme transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097753">
        <property type="term" value="P:membrane bending"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097749">
        <property type="term" value="P:membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990627">
        <property type="term" value="P:mitochondrial inner membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990626">
        <property type="term" value="P:mitochondrial outer membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000001">
        <property type="term" value="P:mitochondrion inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031623">
        <property type="term" value="P:receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000741">
        <property type="entry name" value="Putative mitochondrial dynamin GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056495">
        <property type="entry name" value="LIS_MGM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF212">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24550">
        <property type="entry name" value="LIS_MGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="19">
        <location>
            <begin position="245"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="18">
        <location>
            <begin position="815"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="164"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="910"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="910"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EUC39765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="933" mass="103101" checksum="689A978978B316D8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQQ0</accession>
    <name>W6YQQ0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyruvate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_105345</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2-oxocarboxylate + H(+) = an aldehyde + CO2</text>
            <dbReference type="Rhea" id="RHEA:11628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="EC" id="4.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="12">Binds 1 Mg(2+) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.1" evidence="4"/>
    <dbReference type="EMBL" id="KI964088">
        <property type="protein sequence ID" value="EUC41747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691739.1">
        <property type="nucleotide sequence ID" value="XM_007693549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQQ0"/>
    <dbReference type="STRING" id="930090.W6YQQ0"/>
    <dbReference type="GeneID" id="19118668"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105345"/>
    <dbReference type="eggNOG" id="KOG1184">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_0_2_1"/>
    <dbReference type="OrthoDB" id="3970464at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004737">
        <property type="term" value="F:pyruvate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000949">
        <property type="term" value="P:aromatic amino acid family catabolic process to alcohol via Ehrlich pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02005">
        <property type="entry name" value="TPP_PDC_IPDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07038">
        <property type="entry name" value="TPP_PYR_PDC_IPDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000019">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000024">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012110">
        <property type="entry name" value="PDC/IPDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047214">
        <property type="entry name" value="TPP_PDC_IPDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047213">
        <property type="entry name" value="TPP_PYR_PDC_IPDC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452:SF30">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE ISOZYME 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036565">
        <property type="entry name" value="Pyruvt_ip_decrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="16">
        <location>
            <begin position="15"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="14">
        <location>
            <begin position="212"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="15">
        <location>
            <begin position="411"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <label>1</label>
            <note>substrate; ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <label>1</label>
            <note>substrate; ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <label>2</label>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <label>1</label>
            <note>substrate; ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR036565-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR036565-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC41747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="573" mass="62734" checksum="373F87F957EC748A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRS4</accession>
    <name>W6YRS4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyrate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_9903</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="3"/>
    <dbReference type="EMBL" id="KI964190">
        <property type="protein sequence ID" value="EUC40173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693311.1">
        <property type="nucleotide sequence ID" value="XM_007695121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRS4"/>
    <dbReference type="STRING" id="930090.W6YRS4"/>
    <dbReference type="GeneID" id="19129382"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9903"/>
    <dbReference type="eggNOG" id="KOG0409">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035117_6_1_1"/>
    <dbReference type="OrthoDB" id="21615at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000056">
        <property type="entry name" value="3-hydroxyisobutyrate dehydrogenase a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF7">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="9">
        <location>
            <begin position="8"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="10">
        <location>
            <begin position="197"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="331" mass="34691" checksum="1FDFA4F5B3AB12E8" modified="2014-04-16" version="1">MAFDRTSVAFIGLGVMGYPMAVNLRKKMSSEVTLYICDVSEAAVSRFQAEMSGEGPIRVVQSGFEAVNAAGIVLSMLPGGSAVRSVYCDPQTGILAGAKVAFQKSQAPKLLMECGTIESDVIADVAKSVGDTAHELGDDNYLSFVDAPVSGGPMGAEAGTLTFMVGTNRPDHTFDTVKDILKVMGSPGGIFLCGDIGAGTAFKVINNYLSAITSLAASEALNIGSKLGLNIATLTDVINASGGQCWVTSKSNPVPGIQPNTPASRDYEGGFRIELCRKVLKMGSDLAASVGARTVLDQSTLKAFDECMSDPRYSGKDARVVYKWLNESVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUA3</accession>
    <name>W6YUA3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Elongation factor 1 alpha-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_106997</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the Dom34-Hbs1 complex, also named Pelota-HBS1L complex, composed of dom34 and hbs1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964118">
        <property type="protein sequence ID" value="EUC41135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692356.1">
        <property type="nucleotide sequence ID" value="XM_007694166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUA3"/>
    <dbReference type="STRING" id="930090.W6YUA3"/>
    <dbReference type="GeneID" id="19118959"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106997"/>
    <dbReference type="eggNOG" id="KOG0458">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_3_2_1"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990533">
        <property type="term" value="C:Dom34-Hbs1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002184">
        <property type="term" value="P:cytoplasmic translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16267">
        <property type="entry name" value="HBS1-like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000020">
        <property type="entry name" value="Translation elongation factor EF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000204">
        <property type="entry name" value="Translation elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015033">
        <property type="entry name" value="HBS1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08938">
        <property type="entry name" value="HBS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Tr-type G" evidence="14">
        <location>
            <begin position="390"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="241"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00063537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC41135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="803" mass="88530" checksum="C797F5C200A10489" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV43</accession>
    <name>W6YV43_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964104">
        <property type="protein sequence ID" value="EUC41415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692070.1">
        <property type="nucleotide sequence ID" value="XM_007693880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV43"/>
    <dbReference type="GeneID" id="19123872"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40418"/>
    <dbReference type="eggNOG" id="ENOG502S8CY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004543_2_0_1"/>
    <dbReference type="OrthoDB" id="5346713at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="501"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="621"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="934"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="742"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="981"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1132" mass="121217" checksum="25240D0CEA8F009D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVC9</accession>
    <name>W6YVC9_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_68687</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="7"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="105" mass="12231" checksum="CD031876D3A6C495" modified="2014-04-16" version="1" fragment="single">MGLSRIEILPDELLDLIMCYQDRRALHALCLVSKDMNRIATARLYANIELEKDDFKYLRPLALLFWTSTPHREAVRSLCVRHAYGGNLDPWPNHPDLDTIIRNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVN3</accession>
    <name>W6YVN3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_41915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693908.1">
        <property type="nucleotide sequence ID" value="XM_007695718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVN3"/>
    <dbReference type="GeneID" id="19124155"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41915"/>
    <dbReference type="HOGENOM" id="CLU_2454383_0_0_1"/>
    <dbReference type="OrthoDB" id="4357141at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10319" checksum="C6A6C0FD888AF48E" modified="2014-04-16" version="1">MLTQAISCDPPTAWTSPLQDDAIPYHTRYYRRRGRPSMKEKAQGQQYLTLDEEKALIKYLLLMSELRQPVQINSQARTRLGPLRNATLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVZ3</accession>
    <name>W6YVZ3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_105493</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964090">
        <property type="protein sequence ID" value="EUC41698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691789.1">
        <property type="nucleotide sequence ID" value="XM_007693599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVZ3"/>
    <dbReference type="STRING" id="930090.W6YVZ3"/>
    <dbReference type="GeneID" id="19118692"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105493"/>
    <dbReference type="eggNOG" id="KOG1001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_30_1_1"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF22">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC41698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="100" mass="11401" checksum="9E1D7B69F332EDA7" modified="2014-04-16" version="1" fragment="single">TTSLDMVERGLCSENIRYVRIDGNVAPKNRVYAIEQLRHNPKVRVILLTMSCGACGFNLTAASVLHLLQPQWNPSLEYQAFARVHRLGQTRPVTIFKYIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWC3</accession>
    <name>W6YWC3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_8482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964083">
        <property type="protein sequence ID" value="EUC41855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691617.1">
        <property type="nucleotide sequence ID" value="XM_007693427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWC3"/>
    <dbReference type="STRING" id="930090.W6YWC3"/>
    <dbReference type="GeneID" id="19126543"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8482"/>
    <dbReference type="HOGENOM" id="CLU_1389991_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="196" mass="22186" checksum="E40E37792E078862" modified="2014-04-16" version="1">MSMPSSQATKLGTPENKLSSQRTRNPQEEEDAIPTALNEEIIERSRKRIEGNIRMNKIEIQRMHLVVSRDANWDGLGLPPTHKFWQYRRIETNNVKAAMEFVPKWLLSEEVQWDPDTEEAIILSPGELYGVSVGYDFNILGAALMEAHKQNATALKLKISDTPLGGAMIPTKKTKKRKKEEKVITLVAEALIHEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWM1</accession>
    <name>W6YWM1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_8425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964080">
        <property type="protein sequence ID" value="EUC41923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691545.1">
        <property type="nucleotide sequence ID" value="XM_007693355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWM1"/>
    <dbReference type="STRING" id="930090.W6YWM1"/>
    <dbReference type="GeneID" id="19126430"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8425"/>
    <dbReference type="eggNOG" id="KOG3207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017716_3_1_1"/>
    <dbReference type="OrthoDB" id="5273213at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849">
        <property type="entry name" value="LEUCINE RICH REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="3">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="589" mass="66411" checksum="98F4FA1122D390ED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWT7</accession>
    <name>W6YWT7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 13">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="8 13">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_104605</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="15">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; pentose phosphate pathway; D-xylulose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 13">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="8 13"/>
    <dbReference type="EMBL" id="KI964076">
        <property type="protein sequence ID" value="EUC42015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691463.1">
        <property type="nucleotide sequence ID" value="XM_007693273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWT7"/>
    <dbReference type="STRING" id="930090.W6YWT7"/>
    <dbReference type="GeneID" id="19118545"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104605"/>
    <dbReference type="eggNOG" id="KOG3111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054856_0_0_1"/>
    <dbReference type="OrthoDB" id="1927044at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00411"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000130">
        <property type="entry name" value="Ribulose-phosphate 3-epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004076">
        <property type="entry name" value="PRK05581.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12 15" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="10 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="174"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="225"/>
            <end position="226"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC42015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="252" mass="27026" checksum="AF6B6050845291CA" modified="2014-04-16" version="1">MSPPAIIAPSILSADFGALGKACSDTIAQGADWLHVDIMDGHFVPNMTFGAPVVTKIRSHVDRPATAYAKGTFDCHMMIAEPKRWVRDFKKAGCDLYCFHYEAAVSSTAADSPSTQSDQKTSPKELIRFIHAEGMQAGIAIKPSTPVDVLWEILDSPNKEEVPDMVLVMTVEPGFGGQSFMASELPKVTALRQKYPELHIEVDGGLSEKTIDQAADAGANVIVAGSAVFGAADPGDVIKKLRQAVDSRRGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXC0</accession>
    <name>W6YXC0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxymuconolactone decarboxylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_109482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964190">
        <property type="protein sequence ID" value="EUC40174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693312.1">
        <property type="nucleotide sequence ID" value="XM_007695122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXC0"/>
    <dbReference type="STRING" id="930090.W6YXC0"/>
    <dbReference type="GeneID" id="19119442"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109482"/>
    <dbReference type="eggNOG" id="ENOG502SHW8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096750_0_0_1"/>
    <dbReference type="OrthoDB" id="10250730at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33930">
        <property type="entry name" value="ALKYL HYDROPEROXIDE REDUCTASE AHPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33930:SF2">
        <property type="entry name" value="BLR3452 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxymuconolactone decarboxylase-like" evidence="1">
        <location>
            <begin position="30"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxymuconolactone decarboxylase-like" evidence="1">
        <location>
            <begin position="186"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="260" mass="29088" checksum="63A33BB41690E979" modified="2014-04-16" version="1">MNQELKETFIANLGEWEWDESWKSFSELDPEFFEASVRLKAVPKKSEHLSPKVQSFISLAVNSSSTHLYAPGVRANIKEALANGATGAEIKEIIQLTSTLGIHACNVGVPTLVEVMKEEGLYDSHPTAGKPLDASKLQLQEDFTQKRGYWHSFWEEFLALDPDFFAAYTTFSSAPWLPDDSKAKNLGVLEPKVKELIYCAFDAAATHLYRPGLKEHMRNALRYGATVEEILEVLEIASQLSIHTANLAYPILAEELESKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXH7</accession>
    <name>W6YXH7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">COCMIDRAFT_104010</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24 25">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="KI964068">
        <property type="protein sequence ID" value="EUC42243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691243.1">
        <property type="nucleotide sequence ID" value="XM_007693053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXH7"/>
    <dbReference type="STRING" id="930090.W6YXH7"/>
    <dbReference type="GeneID" id="19118423"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104010"/>
    <dbReference type="eggNOG" id="KOG0214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_5_1_1"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005721">
        <property type="term" value="C:pericentric heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140727">
        <property type="term" value="P:siRNA-mediated pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000013">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007175">
        <property type="entry name" value="PRK09606.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="18">
        <location>
            <begin position="39"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="291"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="19">
        <location>
            <begin position="501"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="20">
        <location>
            <begin position="600"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="21">
        <location>
            <begin position="707"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="15">
        <location>
            <begin position="787"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="1161"/>
            <end position="1253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EUC42243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1262" mass="142810" checksum="1DB1C34C2A63AB73" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXQ4</accession>
    <name>W6YXQ4_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_8040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="eggNOG" id="KOG1256">
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    </dbReference>
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    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
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    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
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    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="71"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC42340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="705" mass="78111" checksum="C72CEFA33AC2B5B3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXT5</accession>
    <name>W6YXT5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lytic polysaccharide monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_30669</name>
    </gene>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964170">
        <property type="protein sequence ID" value="EUC40374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694907.1"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="220" mass="24551" checksum="2B913D066AD4BBEB" modified="2014-04-16" version="1">MSPQIWIFLGSGLRHTYRIYDSTNTTGASMHDPGAAHSGGSCQASFSYDNGETWIVVQSWEGNCLRVRKGQEGQLTNSYDMDQSYSFDIPTSLPGADVVIFAWTWLNSSGNREFYMSCSPVQLIAAKSLTKIPSGYPMYIANLQENPETPDSQHPIWSRCYVPQNVWIRYPPRYKGINPPIVADLLPDNSQIRYLDLGDDGGLCGSDNKERVRALALQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXU8</accession>
    <name>W6YXU8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_103644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964063">
        <property type="protein sequence ID" value="EUC42388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXU8"/>
    <dbReference type="GeneID" id="19118349"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103644"/>
    <dbReference type="eggNOG" id="ENOG502RXFP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084522_3_0_1"/>
    <dbReference type="OrthoDB" id="2589563at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02219">
        <property type="entry name" value="cupin_YjlB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014500">
        <property type="entry name" value="UCP019307_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047121">
        <property type="entry name" value="YjiB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448">
        <property type="entry name" value="BLR7373 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448:SF3">
        <property type="entry name" value="CUPIN TYPE-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019307">
        <property type="entry name" value="UCP019307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="70"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="193" mass="21121" checksum="3A2133C1AB52970C" modified="2014-04-16" version="1">MPSLHLTPLSALRISAHYIPSHALIPNTTPHGHPLIIYHSAFPPSTSPSTLEAHVPRNGLSPQWRYTMYSTTHYHSTTHEVLCIFSGRARLLFGGESNPGKVEAEVSAGDAVLVPAGVGHRLVEDVDGGFTMVGSYPKGCSWDMCYGKEGEESKAEAVGHVEWLKKDPLYGDDGPAVWEKEKLNQYRGDKSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXZ4</accession>
    <name>W6YXZ4_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964061">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691034.1">
        <property type="nucleotide sequence ID" value="XM_007692844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXZ4"/>
    <dbReference type="GeneID" id="19123697"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39498"/>
    <dbReference type="eggNOG" id="ENOG502R8EB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2775563_0_0_1"/>
    <dbReference type="OrthoDB" id="3693856at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="69" mass="7471" checksum="F990D5087A086D5A" modified="2014-04-16" version="1">MAMFNQSLTGSTSDPINTRSSHHESSLAVTMPPQDRSRDDPPSPPPQPPPSPAHWSRLVSIDTLAPLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYG2</accession>
    <name>W6YYG2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_98316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964005">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689094.1">
        <property type="nucleotide sequence ID" value="XM_007690904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYG2"/>
    <dbReference type="GeneID" id="19129231"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98316"/>
    <dbReference type="HOGENOM" id="CLU_3055848_0_0_1"/>
    <dbReference type="OrthoDB" id="3765226at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="54" mass="5352" checksum="AA78E3379BA38E6B" modified="2014-04-16" version="1" fragment="single">ALASQATESPSEPAWETQFLESQPKAKITAHTNGVHAGTGSIADGAGAGASRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ54</accession>
    <name>W6YZ54_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_107811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964137">
        <property type="protein sequence ID" value="EUC40814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692661.1">
        <property type="nucleotide sequence ID" value="XM_007694471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ54"/>
    <dbReference type="GeneID" id="19119122"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107811"/>
    <dbReference type="eggNOG" id="ENOG502RZJU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095770_2_0_1"/>
    <dbReference type="OrthoDB" id="2679825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054208">
        <property type="entry name" value="DUF6914"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21858">
        <property type="entry name" value="DUF6914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="185" mass="20603" checksum="78638ED4D7EA081B" modified="2014-04-16" version="1">MPSDKDRLYVALYARSGAPKMPGGEDKYHWAFIIGPKSEGPSANGRRCHVKESLQIIDGKPQNTWAYENLEITLQPTSAILVRIAIGKVADGARLMEAFARTPIRAGYAGYESWNCVSWVQEALTWAAHDGKALGTCHTDWNFVRSIAMWYVEKKAADHRFDGQGQFDTGKVATWDAMEGKELIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1K2</accession>
    <name>W6Z1K2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_53827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689652.1">
        <property type="nucleotide sequence ID" value="XM_007691462.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1K2"/>
    <dbReference type="GeneID" id="19124599"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_53827"/>
    <dbReference type="eggNOG" id="ENOG502SIUZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030055_0_0_1"/>
    <dbReference type="OrthoDB" id="4524805at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="459" mass="50436" checksum="0A08E70896A6ADF6" modified="2014-04-16" version="1" fragment="single">ALLSLLLVATGVSAAPYDFTDNYRDPAPAPEDGPPASYHATRDKSVLPYEICGIVGGYLLTVLIWGVLLLTVGRRMRRKALEPPKQLELELENKPTRPTIKTPGLTSPPLSARSWLRKFKKNDSVPSSPQSPVVQSPSSFDQKVLDAHRDQDQADMERLYAAVMEFDAKKQSARASVDETEPLPLPTDRRRPSAISVARSQDNYDSPASPVRAIYPPGHQDRPTTASNTRDRLRAEQPAPASPRSILSKRSQTSNATASSKNTRFNLKNLRISGPIAKYPGADDDDEARRPLTPRFYAPGAPPSPPTQTNSPTSPYDVDESLDQVQPLPHPAPHRRGSSTTSNNPGLTISTPPPPSKQKSATSPNHSLPLRSFSSPLNSPGIQTTVLDRRVDRLALGTPKTGVPFTPYSPYMPFTPVTPVTPHLTTRRDRKMEKKMEGRRRRGGEEMVQTPKEIFGDAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z303</accession>
    <name>W6Z303_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication factor C subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_99050</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689370.1">
        <property type="nucleotide sequence ID" value="XM_007691180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z303"/>
    <dbReference type="STRING" id="930090.W6Z303"/>
    <dbReference type="GeneID" id="19129388"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99050"/>
    <dbReference type="eggNOG" id="KOG0990">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042324_2_0_1"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000028">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000004">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000129">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF9">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="77"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00070184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC44098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="395" mass="43287" checksum="F355583ED84509EE" modified="2014-04-16" version="1">MSDIEDEMDVDAPVDKSISFGGDSKKGKRSAANLPVEAEDTLPCLHRVEKYRPASLDDVEGHKDIIATINKFVDSNRLPHLLLYGPPGTGKTSTVLALARRIYGNKNMRQMVLELNASDDRGIEVVREQIKTFSSTKQIFSAAPKAGDSSLATFKLIVLDEADAMTSTAQMALRRIMEKYTANTRFCIIANYTHKLSPALLSRCTRFRFSPLKDQDIRHLVDKVIEEEKVNITQDATDSLVTLSKGDMRRALNVLQACHASSTPLQSPGKPAVDPSSIVRDQITQTTIYDCIAAPHPSDIKYIIETLLSKNDMTECLRTINNLKTLKGLALADILTAISEELVANDVPPQVMVTWMSGLADIEYRLSGGGSEAIQTGAAIGVVRTGVELLENGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z342</accession>
    <name>W6Z342_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_43297</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689366.1">
        <property type="nucleotide sequence ID" value="XM_007691176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z342"/>
    <dbReference type="GeneID" id="19124205"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_43297"/>
    <dbReference type="eggNOG" id="ENOG502SNZ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_25_1_1"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="33"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="218" mass="23818" checksum="39859089E09874E1" modified="2014-04-16" version="1" fragment="single">MASDQGRINETQVPTALAIVTTFTVLSCACVVLRLYTRRIILRNVGADDYVIIVAQVLNFGVSAGNYAMLAAGGAGRHIEFVQDKLTIFSKVLLAAIALYNATQITIKISLLLQYGKIFPGRNMRLVCNWGTGFLLMWGAAQQVFTPFICTFTNITHIPEGVCVGNNTLAALNAVMNVVTDFLILIVPFKPVLQLQINMLRKIYLLAILCMGLTCITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3Q7</accession>
    <name>W6Z3Q7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_27111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688876.1">
        <property type="nucleotide sequence ID" value="XM_007690686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3Q7"/>
    <dbReference type="GeneID" id="19121064"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27111"/>
    <dbReference type="eggNOG" id="ENOG502SXYW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1294174_0_0_1"/>
    <dbReference type="OrthoDB" id="3921300at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="213" mass="23961" checksum="B88AFAD01388885E" modified="2014-04-16" version="1">MLEKRVPVENPCPEGSTWDSRMCNANINERAYTDICKFDGEDLFIDIPGSCPEENVCMITGNMENDRFIFDAICVPKTPPSQDVITRRDARKRRVLAQYGRRFKKKGVRGGGAENIPVYIDHRAAFITAEFVSVDGDFIVTPSILNGYLKGTTPRVCKSAQYFEQGDRKHCLPADGPKPLSIGGNVSFLYDLDLRLDENTWLFYYMGCGLGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3V1</accession>
    <name>W6Z3V1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_8092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964066">
        <property type="protein sequence ID" value="EUC42289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691170.1">
        <property type="nucleotide sequence ID" value="XM_007692980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3V1"/>
    <dbReference type="STRING" id="930090.W6Z3V1"/>
    <dbReference type="GeneID" id="19125765"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8092"/>
    <dbReference type="eggNOG" id="ENOG502RVDG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_7_2_1"/>
    <dbReference type="OrthoDB" id="4850726at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="141"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="741" mass="83888" checksum="641EE06490C030ED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3X0</accession>
    <name>W6Z3X0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_37552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688837.1">
        <property type="nucleotide sequence ID" value="XM_007690647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3X0"/>
    <dbReference type="GeneID" id="19123271"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37552"/>
    <dbReference type="eggNOG" id="ENOG502R8YC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118688_0_0_1"/>
    <dbReference type="OrthoDB" id="5366606at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="144" mass="15981" checksum="4AD189314E622B25" modified="2014-04-16" version="1">MPRMDAPPPSDEFQIVLSKPFNGAPTHLIEVIGEPNRSANIRLSNYNGGNKSSEKTGSVPQDDVRELMSLVSTLRGFPSHLSKDIYGLDTKIDFNTMEIQWGNQDEDPAMEGGEVAEEQKDEFKRIAESIEALARQFAKQDSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4D0</accession>
    <name>W6Z4D0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_92540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686936.1">
        <property type="nucleotide sequence ID" value="XM_007688746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4D0"/>
    <dbReference type="STRING" id="930090.W6Z4D0"/>
    <dbReference type="GeneID" id="19128099"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92540"/>
    <dbReference type="eggNOG" id="ENOG502S0YX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_572377_0_0_1"/>
    <dbReference type="OrthoDB" id="2740448at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="206"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="230"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="510" mass="55433" checksum="D0FD3D1253684DC3" modified="2014-04-16" version="1">MFGTLHCNSPTKEAEFVERPYGSLNPGMNSACDRCRAYKVKCTVSGKSCSRCRRLKKTCSFTSVRQRSSQRVWKTDVNSKRQESQSSDRSAQPQTSPSPKDSGNEGEDHIKQRGSISSAHTDRNDGSEKGDPHIADYTSHQLSEASSSLSSSSSSSSSSTTSTSSLPFLADYDQREMSEQRDDLCTCSILPFPFCSSSIHYNSPDAMVRSNIGTPQALPTPPASRDETPQQQQQQLLSNSQSHDPQFEMGPIDTESLDITALASSMYWSQGSFEKTCQCLADVIFALEKLEASCSSGSRAGLDSIVANQKEVIELCRCMLKCSNCMAKRENFILLVFMSERIVVACSRIVTMYRMEDGGLRNANNNNNNNNNSNTHTHNHSGATTVAPSQLACLPGSHLSGTTTDMDMDTQCLAAAAAAAASAAAASSSSPSQPTTSGWQQLLLGDYKINSALEWDHLVRALINFQLRAVRALLGDVKSIGTMILGDAQKESLARAETIVNKLEQDIYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4K5</accession>
    <name>W6Z4K5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_96942</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688607.1">
        <property type="nucleotide sequence ID" value="XM_007690417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4K5"/>
    <dbReference type="STRING" id="930090.W6Z4K5"/>
    <dbReference type="GeneID" id="19128952"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96942"/>
    <dbReference type="eggNOG" id="KOG0024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_5_1"/>
    <dbReference type="OrthoDB" id="5363962at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF7">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="9">
        <location>
            <begin position="30"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC44895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="394" mass="41961" checksum="67A0E99EBD1E9F96" modified="2014-04-16" version="1">MAPSALADICPIPARHYTKSSTVVASVLHGPRDLRLETRTISDPAANELQIAIKATGLCGSDCSYYSKFRNGDLQACEPLSLGHESAGIVVAIGNNVTGYQIGDRVALEVGVPCDNCRSCQRGRYNLCPKMRFRSSAKSVPHFQGTLQERINHPAKWCHKLPSHVSMESAALLEPLSVAIHATRRAQIEQGDTAIVFGAGTVGLLTAAMAKVSGATTVVIADIDYGRINYALANGFANKGYIVTAQAQSTEGAGQFAAAKELAADIMQIASLNEIDFEGADVTFDCTGKEVCMQAGLYATRPGGKLIMVGMGTPIQTLPMSASHLKEVDIIGIFRYANTYPTGIKILSAGVLPSLDNMITHRYHGLASTKEAFELAGKTMDKDGNLVVKVLVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4L6</accession>
    <name>W6Z4L6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_92373</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686868.1">
        <property type="nucleotide sequence ID" value="XM_007688678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4L6"/>
    <dbReference type="STRING" id="930090.W6Z4L6"/>
    <dbReference type="GeneID" id="19128063"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92373"/>
    <dbReference type="eggNOG" id="KOG1404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_4_0_1"/>
    <dbReference type="OrthoDB" id="5419315at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005685">
        <property type="entry name" value="PRK07483.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094:SF1">
        <property type="entry name" value="AMINOTRANSFERASE CLASS-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="494" mass="53507" checksum="8A93DCB0648DAD22" modified="2014-04-16" version="1">MAPGLLAESGQSATSTPKPSPAPSTIPATLSNYENNSALLHRSLNEHPHEVTYASGCYLTLSNGRKILDACGGAAVAVLGHGNQEVTAATVAQMNKVSYVHTGFYTTSSAEDLAECILSESMNHGLEKAYFVGSGSEANEAAMKLARQYFWEQGQTQRTHFVSRRLGYHGNTIASMSLSTNISRKVPYDGAITLPNVSYVSPAYPYRSPLQDESDEAYVAYLVEDLDAEFQRIGPHNVIAFFAETVVGATSGCVAPPHGYFAAVQKLCDSYGILVILDEVMCGMGRTGTYFAFEQENIQPDIVTIGKGLGGGFAPIAGVLIGKKVVDVLRRGTASFNHGHTYQAHPVSCATALAVQQIIQRDQLVRRCAEMGVLLDSLLRHAFQGCRFVGDIRGRGLFYAVEFVAERSSKTRLRPSLRFASRVQCLAFEKGVAIYPGPTNSAGTESDHILLAPPYNISVDELEKVVKALKEAYCEVEQEVELLYLQEKSVALKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4W3</accession>
    <name>W6Z4W3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_97217</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688688.1">
        <property type="nucleotide sequence ID" value="XM_007690498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4W3"/>
    <dbReference type="STRING" id="930090.W6Z4W3"/>
    <dbReference type="GeneID" id="19129014"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97217"/>
    <dbReference type="eggNOG" id="KOG3327">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049131_3_1_1"/>
    <dbReference type="OrthoDB" id="425602at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:dTMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006227">
        <property type="term" value="P:dUDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01672">
        <property type="entry name" value="TMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000679">
        <property type="entry name" value="Thymidylate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344:SF1">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate kinase-like" evidence="10">
        <location>
            <begin position="9"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="216" mass="24444" checksum="8DA83A4C14E3D936" modified="2014-04-16" version="1">MARGKLIVFEGLDRAGKSTQCEKLVADLQNDGVKVRHMRFPDRTTPIGQMINSYLSGQSDQEDHVIHLLFSANRWEAAPSIRAELAAGTTVIIDRYYYSGCVYSAAKQNPNMSLEWCRKPDVGLPRPDLCLFLDISADDAAKRGGFGTEKYEKKDMQDRVRELFETLMQKKEGEDFVRIDAGASLEEVAAKVREQADRCIERVAKGRLPLRTVEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z594</accession>
    <name>W6Z594_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_96375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963990">
        <property type="protein sequence ID" value="EUC45155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688364.1">
        <property type="nucleotide sequence ID" value="XM_007690174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z594"/>
    <dbReference type="GeneID" id="19128842"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96375"/>
    <dbReference type="eggNOG" id="ENOG502RJ25">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2049278_0_0_1"/>
    <dbReference type="OrthoDB" id="3662117at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="125" mass="13798" checksum="2499809C3613A90B" modified="2014-04-16" version="1">MLLLSLSLVSASIADTPKTPQKKKACGWELMQNFNISIGSLGALYAKQTGDRSLCTRQDDASEYCTCIYECGNGVWSHHQAKRHEDDDGNDDHNDDDKSTTHVNAWTWEQGCGKYCHAGVCDGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5Q4</accession>
    <name>W6Z5Q4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_5689</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688377.1">
        <property type="nucleotide sequence ID" value="XM_007690187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5Q4"/>
    <dbReference type="STRING" id="930090.W6Z5Q4"/>
    <dbReference type="GeneID" id="19124702"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5689"/>
    <dbReference type="eggNOG" id="ENOG502RZMB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043687_0_0_1"/>
    <dbReference type="OrthoDB" id="5086500at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046536">
        <property type="entry name" value="DUF6601"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414:SF1">
        <property type="entry name" value="SUBTILISIN-LIKE SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20246">
        <property type="entry name" value="DUF6601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="385" mass="44238" checksum="AAC01DAD06A691E7" modified="2014-04-16" version="1">MPAQTNHESYMLKPPFSLQPIPPNSNADADHTESTAGTLSQNGNTPPNNTKPFFQSSTSQPLSALDSLPTITGKSDHIIRPEYEIPEFLAFDLDLARLNRIHGHLWMAGRPMRARPLHRYTMLGMQVIQTQQMDLHLLKFSSKLLIKPLPEWILCHKFWTDWICTHTDSDNGKREPGWLWKSAAGFLVSYVWLVTTPLDLKLAHENSLLPTFVTWHWWKAFVSDFIAHVDIDTLHQVNKRYQFGDLRLGRINTTYRVRYAHTHFVRGYLWGYNRYVIFFQRKFSWVLIVFVFFSVVLSAMEVSFSLPSTSPVSLENDQAFVQAAFVFVVFSMVSVLVILGFVVVIFVGTFAFNMVMAISHAGSEQRKRRELAEKRRQALENGGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6F4</accession>
    <name>W6Z6F4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat shock factor binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_35157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSBP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686162.1">
        <property type="nucleotide sequence ID" value="XM_007687972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6F4"/>
    <dbReference type="STRING" id="930090.W6Z6F4"/>
    <dbReference type="GeneID" id="19122719"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35157"/>
    <dbReference type="eggNOG" id="ENOG502SY5T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168441_3_2_1"/>
    <dbReference type="OrthoDB" id="4159489at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009643">
        <property type="entry name" value="HS1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424:SF0">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06825">
        <property type="entry name" value="HSBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="8574" checksum="D34CFD7A8E5AE5B7" modified="2014-04-16" version="1">MATPQPLGDRSQSDTASVSSNNPEASGELTAVVDDLLNQLNTKFNSISSELLSKMDDMSRRLDNLEATIQSGDGSKGSGSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6Y0</accession>
    <name>W6Z6Y0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_94845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6Y0"/>
    <dbReference type="GeneID" id="19128525"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94845"/>
    <dbReference type="eggNOG" id="ENOG502RH0F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_706298_0_0_1"/>
    <dbReference type="OrthoDB" id="3792666at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="423" mass="48300" checksum="6F62DC64B1C93C5A" modified="2014-04-16" version="1">MRPATRTSLVEFRSILLPPIRIPVHALGALYRPQCSRPAPSCAPLQCLTQRRGMNLYKTARSKTLLGQHKSLTFSSYEIEPPSASSHRINLFETDKHHSKYTLIAKDVSLQEAYDNYVKPGHMIYCTKQLKKGMAKTFMTDAEKKHILDEYKNFSFVEARSHRIALNSPQKGRQLGGLKNIIFNESSPISHFRLSMDRAYQFVDSGSPVEVRIRLQGSVAKEQRLMPGNPAFWPWMHTHFPHLRPDFILKGMPEGTIFLINPVSDGRVCQWVMAKPTAVSTQDLNKRFVKVQKGVIRSIRQGQQEMLPQRMRLQLAESGNENYSPTTGMPKSKAKAKYGQGGSVTYGAEEKKHLAKDAETSRFLQPDEDKTQGAEDKGAVEEEEEEEDVDEDEDEFKPRYRPRHNDKSPPEPKHRWLGRGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6Y1</accession>
    <name>W6Z6Y1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 18">Tryptophan synthase</fullName>
            <ecNumber evidence="6 18">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">COCMIDRAFT_101135</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17 18">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 18">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the TrpB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the TrpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="6 18"/>
    <dbReference type="EMBL" id="KI964033">
        <property type="protein sequence ID" value="EUC43309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690173.1">
        <property type="nucleotide sequence ID" value="XM_007691983.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z6Y1"/>
    <dbReference type="GeneID" id="19117812"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101135"/>
    <dbReference type="eggNOG" id="KOG1281">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1395">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003235_0_0_1"/>
    <dbReference type="OrthoDB" id="10050244at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01115">
        <property type="entry name" value="SLC13_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14478">
        <property type="entry name" value="SPX_PHO87_PHO90_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000151">
        <property type="entry name" value="Tryptophan synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000001">
        <property type="entry name" value="Tryptophan synthase beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000004">
        <property type="entry name" value="Tryptophan synthase beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077:SF3">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="16 18" id="KW-0456">Lyase</keyword>
    <keyword evidence="14 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 18" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <keyword evidence="11 18" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1139"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1170"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1216"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1267"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1348"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1393"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1416"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1446"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1484"/>
            <end position="1517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Han J."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        </source>
    </evidence>
    <sequence length="477" mass="51719" checksum="1C7053A5662287E9" modified="2014-04-16" version="1">MPAQTACPISEVDRALSAYVNSRQDTLRIRRTLSKYLTSTLRPVSASTQLQHLNHECPQNLSAANTNPPGLKDSRLEYLQALRARAKAQAKHNELQASLEQLRTRHVDDNPTQPEPEHDDNVTQGYVFLLRQRRRHAELQVIQESLEKLLSAKPSTPSSDPRDLVKRAIGEQPDVPAERLDNLSQTEDDQVSIFKLKQEVLEARASMERAQAAKIKAQDATPSAPSATLQSQVYALEQARNELVDWIQGELAKLEEESIFLEDASPIKRPVRNGASAAAPDTTNSAIDRASATAKIQASYDKYTAARANLLEAHVSLQNPAPATNSEGDSSTNDNNNNNNNNNNAVSPQTPVNANTDSVASKPTNPISKLLPYLSPLAHIATSERALTQRTVHLAAHLAAADQEAQEALVRLSGESHLLPAAGGSKEAAAWAKVAAEADAATEALVKERLDESAKEVAGVAMIVDLCSLQSRVLDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7J2</accession>
    <name>W6Z7J2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_100602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC43544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7J2"/>
    <dbReference type="STRING" id="930090.W6Z7J2"/>
    <dbReference type="GeneID" id="19117707"/>
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    <dbReference type="eggNOG" id="ENOG502SMXX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="3557394at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="55"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="770" mass="88084" checksum="01A1728395206392" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7L9</accession>
    <name>W6Z7L9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_94635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963978">
        <property type="protein sequence ID" value="EUC45763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687744.1">
        <property type="nucleotide sequence ID" value="XM_007689554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7L9"/>
    <dbReference type="STRING" id="930090.W6Z7L9"/>
    <dbReference type="GeneID" id="19128487"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94635"/>
    <dbReference type="eggNOG" id="ENOG502SI7A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1250602_0_0_1"/>
    <dbReference type="OrthoDB" id="3687751at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="219" mass="24965" checksum="DC278A4EF7CDED28" modified="2014-04-16" version="1">MDPSLPTAVDYDEEPDRIRQDLLSRLHWNVFGPLDEVAVRDGPTLTPLAHHAIKSESIALPPLSKVTIHIDVCQEKYAMDEHDDEDRYQPPSPLVIEKTDGTPISINDFVTLVHPFLNANEEEISKCEDEFHTLPTRLEDGTTFVGVDPDEFTSGDHGHFYRSGNMPANPRFFFDEARFNAADEDEFEIYIVLFVDGNLGVSFDEFWARRAAVTYVHRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7V2</accession>
    <name>W6Z7V2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Copper radical oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_89238</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685700.1">
        <property type="nucleotide sequence ID" value="XM_007687510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7V2"/>
    <dbReference type="STRING" id="930090.W6Z7V2"/>
    <dbReference type="GeneID" id="19127432"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89238"/>
    <dbReference type="eggNOG" id="ENOG502SCD5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013444_1_0_1"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF56">
        <property type="entry name" value="GALACTOSE OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889588" evidence="3">
        <location>
            <begin position="22"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="4">
        <location>
            <begin position="314"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="5">
        <location>
            <begin position="433"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC47792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="531" mass="56898" checksum="B4AE375AC584402E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z863</accession>
    <name>W6Z863_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_6849</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964020">
        <property type="protein sequence ID" value="EUC43754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689719.1">
        <property type="nucleotide sequence ID" value="XM_007691529.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z863"/>
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    </dbReference>
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        <location>
            <begin position="288"/>
            <end position="448"/>
        </location>
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            <begin position="1"/>
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            <position position="172"/>
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        <ligand>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">ATCC 44560</strain>
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        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
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    </dbReference>
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            <end position="659"/>
        </location>
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            <end position="167"/>
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            <begin position="471"/>
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            <dbReference type="Pfam" id="PF24962"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 10">ATCC 44560</strain>
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        <reaction evidence="5">
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    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyrroline-5-carboxylate reductase family.</text>
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        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="7">
        <location>
            <begin position="13"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="8">
        <location>
            <begin position="203"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC47982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="317" mass="33294" checksum="7A3EA9F86071113F" modified="2014-04-16" version="1">MANTQESKPLTLTVLGSGTMGIAIMGGVMSSLASTHTKATIDPSSAPKDVPNLSNFIACDQWAPAEQNVRKALGHYNFPLQTLTNENLKGVQQADIVLLSCKPHGFKTILGEEGMRDALKGKVLVSILAGVTREQIEAFLYPDGPEKAENACRVVRVMPNTASFVGESMSVIQTSDPPLSEAQAKLVEFVFSSIGRVTTLPPANMDVATALCGSGPAFFALMLEAAADGAVAMGLPRAEAQMMAAQTMRGTTGLVLNGEHPAVLKDKVSTPGGCTIGGLMSLEEDGVRGSVAKAIREATVVASRLGGEQKEFVNHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z916</accession>
    <name>W6Z916_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_87797</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685236.1">
        <property type="nucleotide sequence ID" value="XM_007687046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z916"/>
    <dbReference type="STRING" id="930090.W6Z916"/>
    <dbReference type="GeneID" id="19127130"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87797"/>
    <dbReference type="eggNOG" id="ENOG502SPC4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090404_1_0_1"/>
    <dbReference type="OrthoDB" id="73901at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF120">
        <property type="entry name" value="HIGH-AFFINITY COPPER TRANSPORTER CTRA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC48202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="132" mass="14374" checksum="75BC71340D1B3505" modified="2014-04-16" version="1">MSMTFFTSTSTSLFSASWTPTTPGQYAGTCIFLIALAASFRALVAVRFNLFAVLAQAKGQPEIEEKARLEKRHWRADEAVWIASLDVVLAGVSYLLMIAVMTMNVGYFMSVLGGVFLGSLSCGRFMARTVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9K6</accession>
    <name>W6Z9K6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transmembrane protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_92130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686774.1">
        <property type="nucleotide sequence ID" value="XM_007688584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9K6"/>
    <dbReference type="GeneID" id="19128018"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92130"/>
    <dbReference type="eggNOG" id="KOG4267">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096652_3_1_1"/>
    <dbReference type="OrthoDB" id="5620at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF53">
        <property type="entry name" value="TMEM14 PROTEIN HOMOLOG YJR085C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="11322" checksum="F24FD999D66639AA" modified="2014-04-16" version="1">MAEHPSFTLAGLLAVGGTAGYLRTRSTPSLIAGIGLGASYAFAGYRIKQNQDYGTELALGNSVMLAGSAVPRIIKTGGRAPVPIALGVTGALATWYYQKKVREFRYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9Q9</accession>
    <name>W6Z9Q9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_41982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964165">
        <property type="protein sequence ID" value="EUC40441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693035.1">
        <property type="nucleotide sequence ID" value="XM_007694845.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9Q9"/>
    <dbReference type="STRING" id="930090.W6Z9Q9"/>
    <dbReference type="GeneID" id="19124166"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41982"/>
    <dbReference type="eggNOG" id="ENOG502SJA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029473_0_1_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="514" mass="59283" checksum="D218C4B0E86C0D83" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA15</accession>
    <name>W6ZA15_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)</fullName>
            <ecNumber evidence="2">1.2.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_87147</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:13458"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="2"/>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684996.1">
        <property type="nucleotide sequence ID" value="XM_007686806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA15"/>
    <dbReference type="STRING" id="930090.W6ZA15"/>
    <dbReference type="GeneID" id="19126997"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87147"/>
    <dbReference type="eggNOG" id="KOG0525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012907_1_0_1"/>
    <dbReference type="OrthoDB" id="878at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:branched-chain 2-oxo acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007584">
        <property type="term" value="P:response to nutrient"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="5">
        <location>
            <begin position="81"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00051764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="403" mass="44241" checksum="DB400BDB2E674B11" modified="2014-04-16" version="1">MASKTPSPRTLSHYLLRRQTLLRPRGHIRIPNRPYSAAAPGARLNGTVEYDTTPILNHTAKSTLSNPELPAEIRNGQTKRINLYTAINEALRHALQTDERVLVFGEDVQFGGVFRCTMNLAGDFGTERVFNTPLSEQGLVGFAIGAAAEGMKPVAEVQFADYVFPAFDQIHNEAAKYRYRSGSTGVNCGGLVIRMPTGSVGHGALYHTQSPEALFTHTPGLRVVIPRSPVQAKGLLLSAIQCQDPVIFMEPKILYRAAVEQVPVDAYHLPLDKAEVLKTGKDLTIISYGTPLYTCSAAITAAEKDFGCSVELIDLRTIYPWDRETVLESVKKTGRAVVVHESMMNAGVGAEVAATIQEKAFLRLEAPVKRVTGWATHTGLMFEQFVIPDVTRVYDAIKKTLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAI7</accession>
    <name>W6ZAI7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exosome complex component RRP45</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Ribosomal RNA-processing protein 45</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_108091</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964144">
        <property type="protein sequence ID" value="EUC40716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692769.1">
        <property type="nucleotide sequence ID" value="XM_007694579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAI7"/>
    <dbReference type="STRING" id="930090.W6ZAI7"/>
    <dbReference type="GeneID" id="19119183"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108091"/>
    <dbReference type="eggNOG" id="KOG1614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038194_0_0_1"/>
    <dbReference type="OrthoDB" id="10264038at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd11368">
        <property type="entry name" value="RNase_PH_RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.70:FF:000005">
        <property type="entry name" value="Exosome complex component RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033100">
        <property type="entry name" value="Rrp45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF14">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0271">Exosome</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="11">
        <location>
            <begin position="33"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="12">
        <location>
            <begin position="190"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00077933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC40716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="291" mass="32350" checksum="3C5A9A9897367999" modified="2014-04-16" version="1">MPREAEISLNEREFIKQALQEQIRIDRRAFDAFRPLELTFGDEYGVADVQLGKTRVIARISVDVTTPPPERKFDGIFQIVTEFSPMASPAFEVGRPTDAEVILSRILEKAIRRSNALDTESLCIIAGLKCFALRADVHIVDHDGGLIDASCIAVMAALQHFRRPDVVVEGEKATILSVREREPIPLSILHQPLCVTFSYFEGEIFLVDANLAEEQVRQGEVIITMNKHGEVCQIAKYGGATIHPLALLNCTNIAQQKVKEIGAFIQKRLEEDAKERDAGGLMAELSAENAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB82</accession>
    <name>W6ZB82_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_2120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684381.1">
        <property type="nucleotide sequence ID" value="XM_007686191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB82"/>
    <dbReference type="GeneID" id="19120018"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2120"/>
    <dbReference type="eggNOG" id="ENOG502SSM9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072615_1_0_1"/>
    <dbReference type="OrthoDB" id="4424523at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="274" mass="31516" checksum="716B27ECD39D5FEB" modified="2014-04-16" version="1">MSADDSPSTAEVLRRLKEEMAQQGPRTHKEHHAIETSLSHPYLQSDTKWGFVIIRAAYGPSSDALWAQFLEIFRANVEETLRLEEELDLLPRHEITIIEDETTLAGADSYAARRAFRAWVANDLPQRLRGSYLEELGGLTQVREKLLSNDAHNAPGTTHPASLVPPRWKYCIFVDQDCLRSVAKGPEEPELKDPAMKILTTDWERDEVEVPIEEFTRDWDGGETNDDAEEVGWMYMDMTDYVTVYDRLTGTFAWEEYYQRPYKSYVDDSDSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB84</accession>
    <name>W6ZB84_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diphthamide biosynthesis protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_37522</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DPH4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688797.1">
        <property type="nucleotide sequence ID" value="XM_007690607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB84"/>
    <dbReference type="STRING" id="930090.W6ZB84"/>
    <dbReference type="GeneID" id="19123264"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37522"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_7_0_1"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF46">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="J" evidence="12">
        <location>
            <begin position="6"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="DPH-type MB" evidence="13">
        <location>
            <begin position="137"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC44704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="215" mass="23927" checksum="9645EA2BED066CB7" modified="2014-04-16" version="1">MAYTKDYYHILSLDAPGWRQPANQANKTTAAAAADLRRAYKVALLAAHPDKKKRDAIPTTTLTTKSKPAYTVDDVKEAYTILADPKTRAEYNTWFLHNRHTLRFSTTPTTTTTTTTSSGITPQEQAQAIISEDFILGLELVDLSDFEEVQHAAADARGGRQGVEWTRGCRCGDEKGFRIVEDELEDAQVRGENEVLVGCQGCSLWLRVGFEVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBC8</accession>
    <name>W6ZBC8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_97345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688758.1">
        <property type="nucleotide sequence ID" value="XM_007690568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBC8"/>
    <dbReference type="GeneID" id="19129040"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97345"/>
    <dbReference type="eggNOG" id="ENOG502RS2E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_368466_0_0_1"/>
    <dbReference type="OrthoDB" id="3791063at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
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                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963986">
        <property type="protein sequence ID" value="EUC45324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688142.1">
        <property type="nucleotide sequence ID" value="XM_007689952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD09"/>
    <dbReference type="GeneID" id="19128740"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95873"/>
    <dbReference type="HOGENOM" id="CLU_2157926_0_0_1"/>
    <dbReference type="OrthoDB" id="10318117at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="111" mass="12057" checksum="0DEA5C2B8BB2AFF1" modified="2014-04-16" version="1">MSKTHDTSHTRIFNPSAALLLCCSCYTHYTTLTLLPCILRIPRCCCPNTLSASSRHRLADPHRRSLRRLGTAIVIESSSTAASGHNNTPPAPFFVPLSLSPVSRKAVLSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD73</accession>
    <name>W6ZD73_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_89188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685689.1">
        <property type="nucleotide sequence ID" value="XM_007687499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD73"/>
    <dbReference type="STRING" id="930090.W6ZD73"/>
    <dbReference type="GeneID" id="19127422"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89188"/>
    <dbReference type="eggNOG" id="ENOG502QVJG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_4_0_1"/>
    <dbReference type="OrthoDB" id="5405781at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF128">
        <property type="entry name" value="ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="10"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="444" mass="51084" checksum="E1AF9B9DFCFF49D7" modified="2014-04-16" version="1">MASSNRQNVTWVEGVRGVASFWVVVTHLCRAWDYSLWSPRDSENAAPQLLQLPFIRLPFQGRIGVTMFAFLTGYVCAIKPLRQAKSGNIPAALETLGKSAFRRPPRLIMPATIALVIAWFFAQLGAFEIAHLSDSHWFRRSVPTNIGSLDTEIPRLIRNFQTSWSGANNEYDDHQWALLPLLQGAFLIYILLFATVFMKFRMRLFTCVVLFFWYWMRTSPEKETFECQFLYGVILCDLGSEKGFRDFVNNRVKARRFATAFLIILGWYVACFPGEHWEWATWSVQLKNLGDWIIPQGAASYPKRFTAIGWDLMVTGIWLSPSLQSLFSNKLFMWVGRNSFAVYLTHGTVMKVGLARLIYGFSTAPYRVEQPKDGQGEAIHHYIPRTTNWLVWTLAIPLFFVVEYTIAHLWITYVDSQCARATKWLEDTMFEKSEDEKHGAANMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDF4</accession>
    <name>W6ZDF4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Poly(A) polymerase</fullName>
            <ecNumber evidence="11">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_36767</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerase that creates the 3'-poly(A) tail of mRNA's.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions. Also active with manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="11"/>
    <dbReference type="EMBL" id="KI963983">
        <property type="protein sequence ID" value="EUC45484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687975.1">
        <property type="nucleotide sequence ID" value="XM_007689785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDF4"/>
    <dbReference type="STRING" id="930090.W6ZDF4"/>
    <dbReference type="GeneID" id="19123106"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36767"/>
    <dbReference type="eggNOG" id="KOG2245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011511_4_1_1"/>
    <dbReference type="OrthoDB" id="412748at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071920">
        <property type="term" value="C:cleavage body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033620">
        <property type="term" value="C:Mei2 nuclear dot complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990251">
        <property type="term" value="C:nuclear exosome focus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180010">
        <property type="term" value="P:co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033621">
        <property type="term" value="P:nuclear mRNA surveillance of meiosis-specific transcripts"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000002">
        <property type="entry name" value="Poly(A) polymerase alpha, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1410.10:FF:000001">
        <property type="entry name" value="Putative poly(A) polymerase gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014492">
        <property type="entry name" value="PolyA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018425">
        <property type="entry name" value="PolyA_polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="18">
        <location>
            <begin position="12"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="17">
        <location>
            <begin position="214"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="16">
        <location>
            <begin position="361"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="519"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="540"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="91"/>
            <end position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="104"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
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        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
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    <feature type="binding site" evidence="13">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="241"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR018425"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR018425-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC45484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="578" mass="64947" checksum="9B66AADC128BC43E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDF6</accession>
    <name>W6ZDF6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_83732</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
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    </reference>
    <comment type="function">
        <text evidence="11">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
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        <subcellularLocation>
            <location evidence="11">Nucleus</location>
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    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase T1B family.</text>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="F:threonine-type endopeptidase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:proteasome core complex assembly"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
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    </dbReference>
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        <property type="entry name" value="proteasome_beta_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000013">
        <property type="entry name" value="Proteasome subunit beta type-5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
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    </dbReference>
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        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
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        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF3">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC49857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="283" mass="30985" checksum="979627B6B10BFDE7" modified="2014-04-16" version="1">MDSLVSQYSRPAYTEEGPSEEEQLQLYSGAPELSLKFALPPVAQSASWLRAMTDDYSNPNCPIKIAHGTTTLAFRFKGGIIVATDSRATAGNWIASQTVKKVIEINSCLLGTMAGGAADCQYWLAYLGMQCRLHELRHKRRISVAAASKILANLVYSYKGMGLSMGTMCAGVTPQEGPALYYIDSDGTRLAGNLFCVGSGQTFAYGVLDAQYKYDLEDDEALELGRRSILAATHRDAYSGGFINLYHVKEDGWVKHGFNDTNPIFWETKLKKGEFSNVTSALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE65</accession>
    <name>W6ZE65_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_52470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685164.1">
        <property type="nucleotide sequence ID" value="XM_007686974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE65"/>
    <dbReference type="GeneID" id="19124544"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_52470"/>
    <dbReference type="eggNOG" id="ENOG502SSR4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087045_1_0_1"/>
    <dbReference type="OrthoDB" id="5423884at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="197" mass="21962" checksum="8CDCA7A389B679E4" modified="2014-04-16" version="1" fragment="single">MPVFRQHLDAVAAQIDRIASRDAILTPRQPLVNAPAIALDAPKPAQLAKRQNVIYTQQGIIPTYYDLSGPEPGTVVGIVLGSVAGFLLICWLLQSLVNGSRSAGTTTAMAGEEEIVVRRPRRNSHGGRSSRRRSEVREVSRSPRTSGARSHIIVEERRQPVRPRSIVVEDRHRVPGDNVVEVIEEHEDYRERRGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEA8</accession>
    <name>W6ZEA8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_87647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685185.1">
        <property type="nucleotide sequence ID" value="XM_007686995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEA8"/>
    <dbReference type="GeneID" id="19127108"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87647"/>
    <dbReference type="HOGENOM" id="CLU_2468891_0_0_1"/>
    <dbReference type="OrthoDB" id="3690239at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="109" mass="12268" checksum="7D6A35EF6692A10E" modified="2014-04-16" version="1">MHWQPLDQVGIVLTDYHCNYLLSLTYPLFLVAWWLGKPLSTCQQSPHGEAGCSLCLLSITMDILCPRFKPSQPCSRYMAILLGDLGSKLFSSETLVVNVFFSSPHYTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEI7</accession>
    <name>W6ZEI7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_4965</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687555.1">
        <property type="nucleotide sequence ID" value="XM_007689365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEI7"/>
    <dbReference type="STRING" id="930090.W6ZEI7"/>
    <dbReference type="GeneID" id="19124443"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4965"/>
    <dbReference type="eggNOG" id="KOG2901">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024840_0_0_1"/>
    <dbReference type="OrthoDB" id="5595109at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12710:FF:000004">
        <property type="entry name" value="Protein arginine methyltransferase NDUFAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF7">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="528" mass="57187" checksum="86FA659F06B0028B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEY6</accession>
    <name>W6ZEY6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Alpha-amylase</fullName>
            <ecNumber evidence="4 14">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_93878</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4 14"/>
    <dbReference type="EMBL" id="KI963972">
        <property type="protein sequence ID" value="EUC46069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687427.1">
        <property type="nucleotide sequence ID" value="XM_007689237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEY6"/>
    <dbReference type="STRING" id="930090.W6ZEY6"/>
    <dbReference type="GeneID" id="19128345"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93878"/>
    <dbReference type="eggNOG" id="KOG0471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_7_2_1"/>
    <dbReference type="OrthoDB" id="204980at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11319">
        <property type="entry name" value="AmyAc_euk_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05811">
        <property type="entry name" value="CBM20_glucoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000120">
        <property type="entry name" value="Alpha-amylase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000552">
        <property type="entry name" value="Related to glucoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034836">
        <property type="entry name" value="CBM20_glucoamylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF212">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="10 14" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886963" description="Alpha-amylase" evidence="16">
        <location>
            <begin position="21"/>
            <end position="587"/>
        </location>
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        <location>
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            <end position="587"/>
        </location>
    </feature>
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            <end position="587"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC46069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="587" mass="63110" checksum="F60A207A43C10241" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF24</accession>
    <name>W6ZF24_COCMI</name>
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        <recommendedName>
            <fullName evidence="9">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_23666</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
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    </comment>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="P:regulation of pseudohyphal growth"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
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        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
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    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23227">
        <property type="entry name" value="HEAT_MROH2B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="8">
        <location>
            <begin position="386"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1081" mass="119051" checksum="6E06B1F583B4AD5B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF84</accession>
    <name>W6ZF84_COCMI</name>
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        <recommendedName>
            <fullName evidence="15">PLD phosphodiesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_86721</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686689.1"/>
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    <dbReference type="GeneID" id="19126917"/>
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    <dbReference type="eggNOG" id="KOG2031">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010413_2_0_1"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09123">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.870.10:FF:000038">
        <property type="entry name" value="Probable tyrosyl-DNA phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="449"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="11">
        <location>
            <position position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC48660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="578" mass="64968" checksum="31C79A109A49EA4B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFP6</accession>
    <name>W6ZFP6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_25644</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963968">
        <property type="protein sequence ID" value="EUC46324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687157.1">
        <property type="nucleotide sequence ID" value="XM_007688967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFP6"/>
    <dbReference type="STRING" id="930090.W6ZFP6"/>
    <dbReference type="GeneID" id="19120799"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25644"/>
    <dbReference type="eggNOG" id="KOG2000">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006331_0_0_1"/>
    <dbReference type="OrthoDB" id="775571at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1900:FF:000013">
        <property type="entry name" value="Spindle pole body component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045818">
        <property type="entry name" value="GCP6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF70">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19340">
        <property type="entry name" value="GCP6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-tubulin complex component 6 N-terminal" evidence="8">
        <location>
            <begin position="82"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="7">
        <location>
            <begin position="162"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="6">
        <location>
            <begin position="566"/>
            <end position="920"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC46324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="923" mass="104483" checksum="0C69A544BBC7788A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFW4</accession>
    <name>W6ZFW4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_23539</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684710.1">
        <property type="nucleotide sequence ID" value="XM_007686520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFW4"/>
    <dbReference type="GeneID" id="19120456"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23539"/>
    <dbReference type="eggNOG" id="ENOG502SHCE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_8_2_1"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF2">
        <property type="entry name" value="FAD-BINDING MONOOXYGENASE AUSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="593" mass="66979" checksum="297D597BCCA5998A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGD0</accession>
    <name>W6ZGD0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_85931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684546.1">
        <property type="nucleotide sequence ID" value="XM_007686356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGD0"/>
    <dbReference type="GeneID" id="19126766"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85931"/>
    <dbReference type="HOGENOM" id="CLU_2687439_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="74" mass="8538" checksum="3AE2FD5ECA4CBA52" modified="2014-04-16" version="1">MEIYCDYYTIASPELKRKHNQIPYHLHQSFWNQASPTILFAEALSSGFQHSILPAILPTLLISSLLKSRLFYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH57</accession>
    <name>W6ZH57_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_102304</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964046">
        <property type="protein sequence ID" value="EUC42881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690605.1">
        <property type="nucleotide sequence ID" value="XM_007692415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZH57"/>
    <dbReference type="GeneID" id="19118056"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102304"/>
    <dbReference type="eggNOG" id="ENOG502T0ZY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121037_1_0_1"/>
    <dbReference type="OrthoDB" id="3649348at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="139" mass="14923" checksum="7B51942FAD99F2F9" modified="2014-04-16" version="1">MATRSIPFILCGRTPQIAKAVREGVAPEYHVPHTFLSLEDAKSNIPPLLSPTNPSRPVAVVLGGGFDDAMFAEIKEACDTAQGGKEVAWLRTDITGKVEMPDMNDREAYGKAMGARLKRGLEGLGVGREEGVKGGVHFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHF6</accession>
    <name>W6ZHF6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_31429</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SPT3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682132.1">
        <property type="nucleotide sequence ID" value="XM_007683942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHF6"/>
    <dbReference type="STRING" id="930090.W6ZHF6"/>
    <dbReference type="GeneID" id="19121865"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31429"/>
    <dbReference type="eggNOG" id="KOG3902">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038706_1_1_1"/>
    <dbReference type="OrthoDB" id="66982at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001403">
        <property type="term" value="P:invasive growth in response to glucose limitation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007124">
        <property type="term" value="P:pseudohyphal growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd22926">
        <property type="entry name" value="HFD_SPT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000023">
        <property type="entry name" value="transcription initiation protein SPT3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003195">
        <property type="entry name" value="TFIID_TAF13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380:SF16">
        <property type="entry name" value="TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02269">
        <property type="entry name" value="TFIID-18kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="262"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC51287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="327" mass="37155" checksum="7CC9B7595DB97F41" modified="2014-04-16" version="1">MSDKDKLAKYRTEIQQMMFVSGETGEPSPETTTLIESIVQDQVQHMLRECTALATRRGSKSISTDDLFMLIRHDRAKISRLRHFLQWKDVRRSVKDSDDKGGDAGADVGAGDADIAVGVVGAGGPGAAPVDASKKAKRAKVDLVWDVQSFFTEFPPQKDDVEDEEEEEMNYATLQRLKNADERTKNMTREEYVHWSDCRQASFTYRKSKRFKEWAGFGLITDSKPSDDIIDILGFLTFEIVQTLTEEALKVKDAEDLYKKNHGGEQNRLKRKRERGLFDPPEEAREPVQPSHVQEAYRRLQRGNNKAKAMLNFTRAVHRSALKLVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHH2</accession>
    <name>W6ZHH2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_1828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684047.1">
        <property type="nucleotide sequence ID" value="XM_007685857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHH2"/>
    <dbReference type="GeneID" id="19119954"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1828"/>
    <dbReference type="HOGENOM" id="CLU_088987_0_0_1"/>
    <dbReference type="OrthoDB" id="3776562at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="201" mass="22757" checksum="4DF03DD5FE861820" modified="2014-04-16" version="1">MATLPGSSETEASPVAHGAPTTFHDWPQLSNELKLEVLSYLLTFSVGIDIYRGTPSYDSRMEDSHQKRLDDHLFPLIATRNSNLAHLAQEAYYKHNIFILHFMFDFDNITYWPKASCAKKIRHVMIYLGLYTGSTLEELLLDCQGAALFRPTKNLGTDAITCPKGKAEATRIAETIQDHQETYPLFNNLQTLFIDASISER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHS3</accession>
    <name>W6ZHS3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carbohydrate-binding module family 18 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_1783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
    <sequence length="82" mass="8758" checksum="F389E49961CFC346" modified="2014-04-16" version="1">MKFATQLFTVAALLGATLAAPAADSNMIEVRDALTNEVMEGMAIDKRQVCYCYGGFCTPGCHGKVKRQVCYCYGGVCTPGCH</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wang R."/>
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                <person name="Steffenson B.J."/>
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                <person name="Han J."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
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    </evidence>
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        <source>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Grimwood J."/>
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    </evidence>
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    <sequence length="75" mass="8821" checksum="0D41C4E785EA514B" modified="2014-04-16" version="1">MGPWFALFEAWAVARLIRSPAFNRAVQKAYRKINRLPDFEQKNGGGRTGPSSFDHFKDEVKNQFRELTWQKRPPK</sequence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_22359"/>
    <dbReference type="HOGENOM" id="CLU_2084628_0_0_1"/>
    <dbReference type="OrthoDB" id="3780845at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="117" mass="12896" checksum="82D70E888A867824" modified="2014-04-16" version="1">MSHTHRYHVKYPSRGTLAPIGIPNHRNAFAVYLLWARQRYYRMHDAMHHEASSSAACTRSSDDAVDVHVGGDAPNSLPSLQFDAARLNTDLLGIGSGLDGSVDASELMYPREIDFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJR1</accession>
    <name>W6ZJR1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_34752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685750.1">
        <property type="nucleotide sequence ID" value="XM_007687560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJR1"/>
    <dbReference type="GeneID" id="19122632"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34752"/>
    <dbReference type="eggNOG" id="ENOG502SN3Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081038_0_0_1"/>
    <dbReference type="OrthoDB" id="5425556at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="2"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="311" mass="34480" checksum="E0A4A08A7D632952" modified="2014-04-16" version="1">MSPHILSLPAELLSQIITSLPLPSLLRFSETCRPARTLANANLQSLSLGIPPYPPHTHSPHQTTVHPTPDRHPHDHWLHIPNITTYPYTTLSNFQSALLTTLLTRHAPLLSHVDITLWTMSVRMAHALRNLSALQRLSLRFDAGSHGRAVERAQMALDREEQRKAWGVLGAETPSWGRRLLGLRVEGAVVGTAEVAVLLKESRGCEELCLERCSGVDGGIWDFLGSWCGKERVRRVEFGECGGVIGEGVLSIIGGMGGLEYLNVYDCQEELAPGTLERWNEEVWRIPHFVAPRPSAFGVDMVIEVDPEYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKS8</accession>
    <name>W6ZKS8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_34340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685314.1">
        <property type="nucleotide sequence ID" value="XM_007687124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKS8"/>
    <dbReference type="GeneID" id="19122539"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34340"/>
    <dbReference type="eggNOG" id="ENOG502S0AG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033002_1_0_1"/>
    <dbReference type="OrthoDB" id="552755at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037647">
        <property type="entry name" value="HIRIP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410:SF2">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="403" mass="43752" checksum="05FD213230EAA296" modified="2014-04-16" version="1">MSDSEGGKPSEATITSKLRDIVIAIHKSGKTDDLTVKRVRARAEKELGLDEGFFKTDASWKEKSQKTIVDAVDKFCSDEPSPKPTPKKAAPKPKAKPAPKKSKPATESPRGVKRKAAAPAKKPKKRAKSESEESEADLSEPPAEISDAESEPPKKPVRRGKKVVAEDSDEEDAPKPSSKPRAAAADDDDETEPAPPKPSDTKGDVSDSDLSSVIDEEPVKKKKKTPAAKGKKEKAPPKAKAAPKAKAEDDPDTAEVKRLQGWLVKCGIRKVWSRDPELSKCDTSKDKIRVLKGWLKDVGMDGKYSNEKAAKIKEKREFAKDLEAIQEGELAWGKTNEVTATGRPSRRAAAKPVPQQKVVLEDDSEEEDAPEGDDDDDDDDVEVDDGDDDDGDKSEDSVGDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL30</accession>
    <name>W6ZL30_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_47598</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964007">
        <property type="protein sequence ID" value="EUC44306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689205.1">
        <property type="nucleotide sequence ID" value="XM_007691015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL30"/>
    <dbReference type="STRING" id="930090.W6ZL30"/>
    <dbReference type="GeneID" id="19124365"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_47598"/>
    <dbReference type="eggNOG" id="ENOG502S84A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093522_4_0_1"/>
    <dbReference type="OrthoDB" id="4590138at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474:SF1">
        <property type="entry name" value="FUNGAL SPECIFIC TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="73" mass="8001" checksum="EE6BFC8DE28D05DC" modified="2014-04-16" version="1" fragment="single">PLPLPSPSTATNETTTQLNVDGQAVKLDHLGPLVVNKDGTLSRIANWESMAEIERQNTLRILVKRNQVRLGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLH1</accession>
    <name>W6ZLH1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_31811</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682546.1">
        <property type="nucleotide sequence ID" value="XM_007684356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLH1"/>
    <dbReference type="GeneID" id="19121967"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31811"/>
    <dbReference type="eggNOG" id="ENOG502SACR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1338239_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000420">
        <property type="entry name" value="Yeast_PIR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00399">
        <property type="entry name" value="PIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50256">
        <property type="entry name" value="PIR_REPEAT_2"/>
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        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
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            <begin position="17"/>
            <end position="182"/>
        </location>
    </feature>
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        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
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        <location>
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            <end position="160"/>
        </location>
    </feature>
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            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
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            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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            <begin position="89"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="182" mass="16699" checksum="203CCD45755A9521" modified="2014-04-16" version="1">MRFSTISVAFLAGAVAAAPQYDVLPISQISDGQIQAPPATPPAVSAPSAVPSGVPSVVPSAVPSGVPSPSAQVPSPSEVPVGTGPVPLPSATATPVAPGTPGTTPIIIPPGGSNSTVPAPSGSGAQSSGPSASASGSSPAGSTGASSSPTSSASVPQASGAAAGNMVSFGGLVLAIGAAVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM99</accession>
    <name>W6ZM99_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_79975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
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            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM99"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_79975"/>
    <dbReference type="eggNOG" id="ENOG502T2EZ">
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    </dbReference>
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    <dbReference type="OrthoDB" id="5428925at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="22"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="513"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="692"/>
            <end position="731"/>
        </location>
    </feature>
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            <begin position="482"/>
            <end position="509"/>
        </location>
    </feature>
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        <location>
            <begin position="589"/>
            <end position="623"/>
        </location>
    </feature>
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            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
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            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
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            <begin position="153"/>
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        </location>
    </feature>
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            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="572"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="721"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC51143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="731" mass="81040" checksum="9DBE75E7E049E7AE" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6ZMI6</accession>
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        </submittedName>
    </protein>
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            <taxon>Pleosporomycetidae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC51188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="80" mass="8776" checksum="132BDE6A3D443B68" modified="2014-04-16" version="1" fragment="single">LPPATTNPHPPTAPTPPSKTSSNPASQPSRAKPPLTTAAATQPTSPSRAKRVWVAWMSLRLTRMRLGARKRRRRRTDLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZML0</accession>
    <name>W6ZML0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transmembrane protein UsgS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_79661</name>
    </gene>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682182.1">
        <property type="nucleotide sequence ID" value="XM_007683992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZML0"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_79661"/>
    <dbReference type="eggNOG" id="ENOG502QW50">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045443_0_0_1"/>
    <dbReference type="OrthoDB" id="10041630at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38421:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38421">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN USGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC51223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="43456" checksum="C75D9C99D494EBFA" modified="2014-04-16" version="1">MDKIDMANFDVSNFDPNAILRGAQLTLVGVNRALQNPRLFTSDHYRQAAIAVAAGVAIRIIVAIPIVGVRVLLWILSLFIDMSQTGLDESIIDGLHFLEHSVLQIPFFLMTLMRYVTPTLDQMFMDSLRWVDETYVQKHKTDDPHNLRAMYYPNLQMYPDHAPKPEKKEKKPLKQTVIMYATKQSRKAAISLGVLALSYVPYIGRLVLPAASFYTFKKAVGTQPAAAIFAMSLLFPRRYLVSFLQAYFSSRTLMRELLEPYFSRVRYTKEQKKLWFRDRAGVLFGFGLGFYIFVKIPLVGVLIYGLAEASTAYLITKITEPPLPPAEAEKFKQESLRWKNKHEFLDMPWQHMDEYNLAMHRPKEQSEVRQTPRKTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMV3</accession>
    <name>W6ZMV3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamate-5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_5866</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="2"/>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688573.1">
        <property type="nucleotide sequence ID" value="XM_007690383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMV3"/>
    <dbReference type="STRING" id="930090.W6ZMV3"/>
    <dbReference type="GeneID" id="19124762"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5866"/>
    <dbReference type="eggNOG" id="KOG4165">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030231_0_1_1"/>
    <dbReference type="OrthoDB" id="1934954at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000006">
        <property type="entry name" value="Gamma-glutamyl phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001221">
        <property type="entry name" value="PRK00197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063:SF8">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063">
        <property type="entry name" value="GLUTAMATE SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="12">
        <location>
            <begin position="11"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00059423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00075718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC44916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="471" mass="50127" checksum="DC14672C97DB0CAC" modified="2014-04-16" version="1">MSLTNATPLEVAQAARLGSRKLAVLSTDERNAALTAIHDALANAKDEVLAANVQDLEAANKAAAGGTLSASLVKRLDLGKPGKYEDMLQGILDVRDLEDPINKTTAKTLLDDNLVLSRITCPIGVLLIIFEARPEVIANISALAIKSGNAAILKGGRESSNSFAAIASIISKALASTAVPSDCLQLVQTHDVIADLLKQDTYIDLCIPRGGNKLVRYVKDTTTIPVLGHADGICSTYLCSDYPADKATKIILDAKTSYPAGCNALEQLLVEEEALGTSLPVVVEALLQKGVSLRCDNASLAALKGKLDPHSAALLQEAGPEDYDTEFLDYILAIKTVANVEEAVSHINTHGSHHTDAILTTSEATAKSFLAAVDSSSVYWNTSTRMADGQRYGFGTEVGISTNKIHSRGPVGLEGLTIYKWVIVGDAQVSAEYGAGGKQWKHQRLPVGDEESIAQNEEEREVLRKFRASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN64</accession>
    <name>W6ZN64_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ecp2 effector protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684550.1">
        <property type="nucleotide sequence ID" value="XM_007686360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN64"/>
    <dbReference type="GeneID" id="19126769"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85945"/>
    <dbReference type="eggNOG" id="ENOG502STMM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1255874_0_0_1"/>
    <dbReference type="OrthoDB" id="3775566at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887217" description="Ecp2 effector protein domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24001" checksum="EDA915FADFB68B51" modified="2014-04-16" version="1">MLATLFLLAATIATPAIAGIQQSDFSGIGNIYVLKSDNWQTATPKATVGCLDNNGKFISEKSPSNKCGVFSRLDDFPYTLSTSKGNCTFEDDKQDKNTDSYYGKTDSAWSCGERVADIYDQLYTINGFPYVFLCFGDVACFYDAKHTPSSNEVLPFWQYRWGSQQMGITPGHVQLQLMWKKIDDLPGRSEASEFLGPRVRVEEGSQIPLLGKKARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNB3</accession>
    <name>W6ZNB3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_2242</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684489.1">
        <property type="nucleotide sequence ID" value="XM_007686299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNB3"/>
    <dbReference type="STRING" id="930090.W6ZNB3"/>
    <dbReference type="GeneID" id="19120244"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2242"/>
    <dbReference type="eggNOG" id="KOG1287">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_3_6_1"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF512">
        <property type="entry name" value="SOBREMESA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
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            <end position="224"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="244"/>
            <end position="263"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="513"/>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="575"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="624" mass="67475" checksum="8E369404DAE79480" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNE5</accession>
    <name>W6ZNE5_COCMI</name>
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        <recommendedName>
            <fullName evidence="11">5-aminolevulinate synthase</fullName>
            <ecNumber evidence="11">2.3.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">5-aminolevulinic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Delta-ALA synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Delta-aminolevulinate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_2093</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="2.3.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.37" evidence="11"/>
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        <property type="protein sequence ID" value="EUC49024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OrthoDB" id="10263824at2759"/>
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        <property type="reaction ID" value="UER00375"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0005759">
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902117">
        <property type="term" value="P:positive regulation of organelle assembly"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
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    </dbReference>
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        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
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        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
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        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
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        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="187"/>
            <end position="543"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00003076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU910713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC49024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="622" mass="67078" checksum="E2A2F1EB0DF405B1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPX9</accession>
    <name>W6ZPX9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_26216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687814.1">
        <property type="nucleotide sequence ID" value="XM_007689624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPX9"/>
    <dbReference type="GeneID" id="19120899"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26216"/>
    <dbReference type="HOGENOM" id="CLU_2305574_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="100" mass="11005" checksum="A03AC1CF2CAE2487" modified="2014-04-16" version="1">MAEPQDPTACQGVAVVWGVADHALATVRHHVRCTSYPFKFDKGPLFGTGPNAETAKRKGRWGNSLLRNRGGMNSVRDAENSTREPFGRRSVIMSPLSFFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRZ6</accession>
    <name>W6ZRZ6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_68353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
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                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Grimwood J."/>
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        <property type="entry name" value="PH_DOMAIN"/>
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        <location>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="743"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="784"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1004"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1122"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1289"/>
            <end position="1313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1350" mass="149697" checksum="50DACFAA14588970" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUT7</accession>
    <name>W6ZUT7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme E2C-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_3391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685809.1">
        <property type="nucleotide sequence ID" value="XM_007687619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUT7"/>
    <dbReference type="STRING" id="930090.W6ZUT7"/>
    <dbReference type="GeneID" id="19122438"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3391"/>
    <dbReference type="eggNOG" id="KOG4784">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029122_1_1_1"/>
    <dbReference type="OrthoDB" id="386949at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051865">
        <property type="term" value="P:protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019193">
        <property type="entry name" value="UBQ-conj_enz_E2-bd_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31531:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE E3D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31531">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09814">
        <property type="entry name" value="HECT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="54329" checksum="33D9345240C98C73" modified="2014-04-16" version="1">MSRPLLPESAYEALGLSPEALKDLMNPKPAPEPTKVHAPNLLQSDEDNTRPMLPNETSITLYAELLLHIRTVTLFASLRTNHSRQTDAKLSADGSYITVSHEGESATIRLPINVKGAGDAALELPSRPPSKELTLRLQLEEKEGSDLLGALQRQDRQANIVPWDGASLNRAEDVEILCKNCEGVVVPKGKIQQWKDLPNENWAEMMDFWHCHKPDEHHLHNHTHEHAIGQKGYAAANRLQAKEGVGFVDLASFLLAESDCVGVQLSTEENKEEEKPHSILCKHCTQPLGIQDPLTNGWRIHKWRLTLTSKLSNVPPFFSSPQKWISARLLYLIENNAVRKFHIHTPIPSPSNNTKVKPTPSILIWVFTPDLLFSSSIPSPNRFDPTRCMKIFYKRQTWQPFQPGDAESASIEDVEFSKDLYDELDRALQQGRRLLPPTAKKFQGWDVGLLERFEVVEGGMGWVGEEEKDEENEWGIPSEPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUZ5</accession>
    <name>W6ZUZ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_89485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685877.1">
        <property type="nucleotide sequence ID" value="XM_007687687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUZ5"/>
    <dbReference type="STRING" id="930090.W6ZUZ5"/>
    <dbReference type="GeneID" id="19127489"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89485"/>
    <dbReference type="eggNOG" id="ENOG502S0TT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047034_1_0_1"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36839">
        <property type="entry name" value="METALLO-BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G12770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36839:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G12770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="99"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="313" mass="34652" checksum="841D9C8F1E45EBD4" modified="2014-04-16" version="1">MKFSPSDLAICETCGTQYDVPLSQHPETCRICDDPRQYVPASGQSWTNLANSQQTQKNVFETDPKDARIHYISTQPLTPSELPAGLADSSTTRKQLGIGQRAILLQTSHGNVLWDCIALLNPQTIDFINSKGGLKAIVISHPHFYTTHLEWAEAFGCPVYTCRDDAQWLNREDKRGVRKLVGGVTPIEEVEGKVKMVQCGGHFEGSSVAHWDGKLFIADTFMSVPSGFSNAQRIPDTTSYSFMWAYPNMIPLPPPAVLAIWKAIKPFEFDSTYGGFAGQNLSRPDLKAQVLESMKIFLRRGGHEGAEIFGESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWB1</accession>
    <name>W6ZWB1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_88196</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685332.1">
        <property type="nucleotide sequence ID" value="XM_007687142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWB1"/>
    <dbReference type="GeneID" id="19127217"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88196"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_27_5_1"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF27">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="25"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="519" mass="54519" checksum="44E92EE8659A09CD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W7A009</accession>
    <name>W7A009_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684254.1">
        <property type="nucleotide sequence ID" value="XM_007686064.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W7A009"/>
    <dbReference type="GeneID" id="19126626"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85213"/>
    <dbReference type="eggNOG" id="ENOG502SDW5">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122989_0_1_1"/>
    <dbReference type="OrthoDB" id="274752at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019711">
        <property type="entry name" value="ATP_synth_F0_suH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28207">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT H, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28207:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT H, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10775">
        <property type="entry name" value="ATP_sub_h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="128" mass="14210" checksum="DF778467EA8C0951" modified="2014-04-16" version="1">MIAQSIRASRQALVRVARQQPAYVARRTFITPTAVRSADLVQDMYLRELKNYKVPQVKASDAEGQVKKFAIPKAPASPEETDIASELKAYETQTVEVEGASSEDGEVLPQEDWFEEEDESITTPGATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3E7</accession>
    <name>W7A3E7_COCMI</name>
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        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_21865</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3E7"/>
    <dbReference type="GeneID" id="19120132"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21865"/>
    <dbReference type="eggNOG" id="KOG1237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004790_4_1_1"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000085">
        <property type="entry name" value="MFS peptide transporter Ptr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="499"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="70192" checksum="D08DB6A3BF2330CE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4A1</accession>
    <name>W7A4A1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCAAT-binding factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_31812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682547.1">
        <property type="nucleotide sequence ID" value="XM_007684357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A4A1"/>
    <dbReference type="STRING" id="930090.W7A4A1"/>
    <dbReference type="GeneID" id="19121968"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31812"/>
    <dbReference type="eggNOG" id="KOG2154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015945_1_0_1"/>
    <dbReference type="OrthoDB" id="10263185at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="321"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="547" mass="62515" checksum="2C888743FEFE8E2B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A551</accession>
    <name>W7A551_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">LEM-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_31376</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682120.1">
        <property type="nucleotide sequence ID" value="XM_007683930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A551"/>
    <dbReference type="STRING" id="930090.W7A551"/>
    <dbReference type="GeneID" id="19121852"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31376"/>
    <dbReference type="eggNOG" id="KOG3464">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010838_2_0_1"/>
    <dbReference type="OrthoDB" id="2503928at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12935">
        <property type="entry name" value="LEM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1180">
        <property type="entry name" value="MAN1, winged-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025856">
        <property type="entry name" value="HeH/LEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044780">
        <property type="entry name" value="Heh2/Src1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018996">
        <property type="entry name" value="Man1/Src1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041885">
        <property type="entry name" value="MAN1_winged_helix_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808">
        <property type="entry name" value="INNER NUCLEAR MEMBRANE PROTEIN HEH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808:SF2">
        <property type="entry name" value="LEM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12949">
        <property type="entry name" value="HeH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09402">
        <property type="entry name" value="MSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="HeH/LEM" evidence="13">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Man1/Src1-like C-terminal" evidence="12">
        <location>
            <begin position="312"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="75"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="258"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC51231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="777" mass="86495" checksum="DFAA8C5429A4CD29" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMZ0</accession>
    <name>W6YMZ0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Uracil-DNA glycosylase</fullName>
            <shortName evidence="7">UDG</shortName>
            <ecNumber evidence="7 9">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UNG1</name>
        <name evidence="12" type="ORF">COCMIDRAFT_108236</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="7 9"/>
    <dbReference type="EMBL" id="KI964148">
        <property type="protein sequence ID" value="EUC40657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692829.1">
        <property type="nucleotide sequence ID" value="XM_007694639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMZ0"/>
    <dbReference type="STRING" id="930090.W6YMZ0"/>
    <dbReference type="GeneID" id="19119208"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108236"/>
    <dbReference type="eggNOG" id="KOG2994">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032162_2_0_1"/>
    <dbReference type="OrthoDB" id="10031947at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097510">
        <property type="term" value="P:base-excision repair, AP site formation via deaminated base removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.470.10:FF:000007">
        <property type="entry name" value="Uracil-DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003588">
        <property type="entry name" value="PRK05254.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003589">
        <property type="entry name" value="PRK05254.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003592">
        <property type="entry name" value="PRK05254.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264:SF0">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00987">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="11">
        <location>
            <begin position="118"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC40657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="319" mass="35643" checksum="0AC738D2A1AA2509" modified="2014-04-16" version="1">MSLKRKAAAAATDASKKTKQNGSITAFFGPPKTDPNAPPKQTAAAAKFDKDAWVAKLTDEQKDLLQLELDTMHESWLPHLKDVLVTPQFLQLKRFLKQELASGKTVYPPMKDVYSWSRHTPLNTVKVVITGQDPYHGPNQAHGLCFSIRPPNPAPPSLQNIYKALKKEYPDYQPPPNKGGLLIPWAERGVLLINTCLTVRRGEANSHSGKGWELLMQKVIDTVAKVRTNGVVFLAWGTPAQQRTKGIPVDKHLVLKSVHPSPLSAARGFFDCGHFTKCNEWLVQRYGKGGGIDWDLNVKPEKEKGKEEKKENEKKEEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ24</accession>
    <name>W6YQ24_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Homing endonuclease LAGLIDADG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110778</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964272">
        <property type="protein sequence ID" value="EUC39710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693769.1">
        <property type="nucleotide sequence ID" value="XM_007695579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ24"/>
    <dbReference type="GeneID" id="19119667"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110778"/>
    <dbReference type="HOGENOM" id="CLU_2855757_0_0_1"/>
    <dbReference type="OrthoDB" id="3664053at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051289">
        <property type="entry name" value="LAGLIDADG_Endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181">
        <property type="entry name" value="INTRON-ENCODED ENDONUCLEASE AI3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181:SF4">
        <property type="entry name" value="LAGLIDADG ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="65" mass="7725" checksum="6CCBAEA390B7E1F9" modified="2014-04-16" version="1" fragment="single">VEKFTDVFDKVIPIFEKFKLHGVKSKNYEDFKKAALLIKNKQHLTREGLDQIKKIKGSMNKNRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQA2</accession>
    <name>W6YQA2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_105682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964094">
        <property type="protein sequence ID" value="EUC41612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691863.1">
        <property type="nucleotide sequence ID" value="XM_007693673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQA2"/>
    <dbReference type="STRING" id="930090.W6YQA2"/>
    <dbReference type="GeneID" id="19118728"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105682"/>
    <dbReference type="HOGENOM" id="CLU_609725_0_0_1"/>
    <dbReference type="OrthoDB" id="3800277at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="450" mass="51378" checksum="0A63337E0B5886FE" modified="2014-04-16" version="1">MAFRRAHSNYVNLGKLYSIPPWGIVPPYGLARPQSNSVNLGNLYSRPQSKRPAGWAYFEDGSVFILPFGWCAHNVFESRMKIAAHFVNGPTPRMQQVQAKNPHMKRFVVINKDGIQIRNNTLRILARNAQDGQRVSVVDPPFENVELSLDPTGSHPVSARFSDAPQLRYEYRLRNSQALENFRGTLVGGILQPNVRLGNGLRLSNKPEILKPQITAKRRERNQQARRLDESGHRPSKSPVKQLHQLNVPSLREQTPPGRPGKPMPLLRKSPRALDFERREAQLAKREQKLIKLQQQLLQTMQAQSIKSSQGKIHGTQTHDSPDPSTDAKLAAIEERERALERKEELLRYKRKTWLLEQKLAQVTARSLPRRGLHETEADARERGGDVSSNTGMEQEATLDSEFDDAGQSHPRRSYSLDDTTPPEALERLRSRIQLPTRRMMRAGRETRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRM5</accession>
    <name>W6YRM5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Stealth protein CR1 conserved region 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_104447</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691393.1">
        <property type="nucleotide sequence ID" value="XM_007693203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRM5"/>
    <dbReference type="GeneID" id="19118504"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104447"/>
    <dbReference type="eggNOG" id="ENOG502QQMR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005484_1_0_1"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003976">
        <property type="term" value="F:UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046835">
        <property type="term" value="P:carbohydrate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047141">
        <property type="entry name" value="Stealth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031358">
        <property type="entry name" value="Stealth_CR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24045">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24045:SF0">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17101">
        <property type="entry name" value="Stealth_CR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth protein CR1 conserved region 1" evidence="4">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="788" mass="90626" checksum="78987FF947A6494E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS97</accession>
    <name>W6YS97_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6YS97"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_108658"/>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <dbReference type="GO" id="GO:0046933">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019727">
        <property type="entry name" value="ATP_synth_F0_fsu_mt_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28161">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28161:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10791">
        <property type="entry name" value="F1F0-ATPsyn_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="101" mass="11298" checksum="9346416758F334AB" modified="2014-04-16" version="1">MSFITKRGLSTLIPPKIASPNAIGSSPNAVRMQKVVNFYEKLPRGPAPEPEAKGLLGRYAKKYMGKNPSGRPLVHVIGFLIALGYAQNYYFHLRHHKNNEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSJ0</accession>
    <name>W6YSJ0_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_108406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964153">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694703.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_108406"/>
    <dbReference type="eggNOG" id="ENOG502SU37">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141137_1_0_1"/>
    <dbReference type="OrthoDB" id="5201563at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="125" mass="14167" checksum="DEB8F369ABC57AED" modified="2014-04-16" version="1">MSVTTTTNPTTYTLAATLADYDLHHTTTEGGHHDASLNAHPNPAANAQQQQNPSHWPTQHRRVPVYRPVNRELDQSERRVYLNGIEQAFVGVMFTGVFLESTMSKIWRNSFGRVWNVGYKLGGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSK6</accession>
    <name>W6YSK6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_108390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964152">
        <property type="protein sequence ID" value="EUC40605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692883.1">
        <property type="nucleotide sequence ID" value="XM_007694693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSK6"/>
    <dbReference type="GeneID" id="19119234"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108390"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_4_2_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="442" mass="49255" checksum="9E7B57933EF1F328" modified="2014-04-16" version="1">MDQSATTAAYVSGMQESLSMHGNELVELTTYFSIGYALFIVPAQLIQTRVRPSLFLPICEMVWGTLTLCMYKAPNSRTMFALRFFLGVFEATSWPGIVSLIFNWYQPSELATRLAIFGVSGVAGNMFLSVLQAALYKNLNGIAGLGGWQWLFIVSGIMTIFWGFLGLVVIPDSPATTRAIYLTKREREIARERMSDAGILTSEFVGKQVVIKKLRLVAKSPVTYLFFAAYLQFAWSQRANSYLLLYLKGLKKGDGSPLYSTYVVNLIPLIGYSISIVCNIGLNALSDWKKWRWQISCATAALQILSTGVLAGWPNGRGVIMTFYFLTFATAAWGYALLAWLGEILRKEPEARAVVVGMTVTLVYVGHATIPLRVWRTKDSPRYPIGFPLAAAFAAGSILAMIVIKWYVEKNPEILEKGLDWREEIGSELIERTEVAKTDSFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSX6</accession>
    <name>W6YSX6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MADS-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_55728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964147">
        <property type="protein sequence ID" value="EUC40670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692812.1">
        <property type="nucleotide sequence ID" value="XM_007694622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSX6"/>
    <dbReference type="GeneID" id="19124655"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_55728"/>
    <dbReference type="HOGENOM" id="CLU_2326280_0_0_1"/>
    <dbReference type="OrthoDB" id="3791716at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11287" checksum="0206E9CD7029D120" modified="2014-04-16" version="1" fragment="single">MVKPTPQNLTRTFKDRSIGICRKAAQLHSIDSSIRIAIIIEKPGQRPFVFSSEEQGFQWPILMEQYVHAQTPIVKRPSHFVFLNEGLSRGRVKVVKPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTC7</accession>
    <name>W6YTC7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_9338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964135">
        <property type="protein sequence ID" value="EUC40850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692627.1">
        <property type="nucleotide sequence ID" value="XM_007694437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTC7"/>
    <dbReference type="STRING" id="930090.W6YTC7"/>
    <dbReference type="GeneID" id="19128258"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9338"/>
    <dbReference type="eggNOG" id="ENOG502S3ZI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054794_1_0_1"/>
    <dbReference type="OrthoDB" id="539398at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336:SF1">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="2">
        <location>
            <begin position="8"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="295" mass="32723" checksum="4361AB32E187DB3C" modified="2014-04-16" version="1">MVKFYPSLTQEHIDFITKQPLFFVASAPWAGEHVNISPKGHPSKSFAVLGPNTVAYLDATGSGCETISHVYENGRVTVMFASFGPKPQIMRLFCKGKVVEKWDQYFSQIRAKMSTENGDDVDIAGVRAIIVLKIQKVQTSCGFGVPQIANAKTAGTDAVGDAVTFADHEPDKDDGNGFKPRDTMEGWARKMIEKQELGDYQKQFNHRSLDGLPGLMSVRRSYDENLAVEDTKAWLRKVSRQGDAVALGVGLGILLMIFLSLIGILSVKPIFLQKILNFQQRQMGLPEDHSWKSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUM7</accession>
    <name>W6YUM7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_106630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964112">
        <property type="protein sequence ID" value="EUC41260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692236.1">
        <property type="nucleotide sequence ID" value="XM_007694046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUM7"/>
    <dbReference type="STRING" id="930090.W6YUM7"/>
    <dbReference type="GeneID" id="19118892"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106630"/>
    <dbReference type="eggNOG" id="ENOG502SFYT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_956417_0_0_1"/>
    <dbReference type="OrthoDB" id="1681166at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="291" mass="32151" checksum="7ADC58EE646EBA35" modified="2014-04-16" version="1">MSANLDTPEPPPIPRATPSPRTKPLDHPDYPPGDDPNEQQEFDDTPEEDDIPYPEPNAEQPLLPPPNFRPFFALIEDTTSGEHYHPYVHYVFADDDPTIVTAASMRGLGLDDTRYLPHDAPPAGDRRRGREGDEEEVEGEEYEQDPPVESPFPPPIPGVKEHYLIVDVGEDGRTIMDAQSLSPEWQIIDTGVRTAPSFDEDSPDPGYMLRIEGVEIPRKNKGKAEAGIDKLTEAREQQGDIFGALEGLVQGIERGLGIAHKIFSAGRREGEEGIPTDACEDDAEKLVGDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV53</accession>
    <name>W6YV53_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_8857</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI964103">
        <property type="protein sequence ID" value="EUC41428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692047.1">
        <property type="nucleotide sequence ID" value="XM_007693857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV53"/>
    <dbReference type="STRING" id="930090.W6YV53"/>
    <dbReference type="GeneID" id="19127299"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8857"/>
    <dbReference type="eggNOG" id="KOG1371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_10_1"/>
    <dbReference type="OrthoDB" id="9402762at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF3">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="4">
        <location>
            <begin position="49"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="4">
        <location>
            <begin position="155"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="469" mass="51474" checksum="3B15927C588C04D3" modified="2014-04-16" version="1">MSACSSQFSVSPSATPEMVSTPATQSSVLFDDDVAADPLDIEGVSSSFIMVVGGLGYIGSHTTLELLKEGYNVLVIDDLSNSYQNVLTRVKFLAEEFCKEQGRRMPALHFQQLDYRSPQMKTVLANYSSYSVSSKPVSALAHRFPYTNLQRTDSGIDMETDDRQEPVIERRSRITGVIHFAAYKSVEESIRTPLRYYSNNVCGLVDFLGLIEEFGIKNFVFSSSATVYGEGANCGVPLREELCVHHPETFVDGEGRERQVLPGVLGLTSPYGRSKFMCESILADLAVADPTWSITALRYFNPVGCHESGILGEDPRQKPSNLIPVIATVMTGARPVLDIFGTDWNTPDGTAVRDFIHVVDLARGHIAALAASAAGRTKAPFRTYNLGTGNGHTVREVLHSLEEVSQRKIPAREVGRRAGDVGFCVAEVQRAETELQWKAERSLRDCAGDVWNFTKGRCPDVQEVGNAQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVA8</accession>
    <name>W6YVA8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_52447</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="KI964522">
        <property type="protein sequence ID" value="EUC39439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007694042.1">
        <property type="nucleotide sequence ID" value="XM_007695852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVA8"/>
    <dbReference type="GeneID" id="19124541"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_52447"/>
    <dbReference type="eggNOG" id="ENOG502QV0G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_1_2_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC39439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="363" mass="38777" checksum="32BF63C52809EBDC" modified="2014-04-16" version="1" fragment="single">NSCQQLATTLNLLPGISVLNTTHITNGTQIALPDLVPSCANAASYNLATATTDMCRVIVNASSSASSTNRIEAWLPDKWNGRFLATGNGGTGGCIDYGNLQNGASFGFATFGTNGGHDGQSGHDFFLNKPENINDFGYRAIHVEAETGKQVVEHYYGRKADYNYYSGCSTGGRQGFEEAILYPEDFDGILIGAVAVDWLRIVASKGLLARRLGWPDLASPSYVSAAQWAAIVTAQVALLDPLDGVKDGIIDNPTLHNFDPSMLACGIGVLNSSVCLSAAQVNTVREIYQPLANTSGHVVYPSFEVGVPTGVFSANTEVVNGTTIPRLKYGLVDDFWRGAVYNDTSFSVLNFTTKDMDFATNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWT9</accession>
    <name>W6YWT9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alcohol dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="9">1.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_8352</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a primary alcohol + NADP(+) = an aldehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15937"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:15938"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:15939"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.2" evidence="9"/>
    <dbReference type="EMBL" id="KI964077">
        <property type="protein sequence ID" value="EUC41988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691471.1">
        <property type="nucleotide sequence ID" value="XM_007693281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWT9"/>
    <dbReference type="STRING" id="930090.W6YWT9"/>
    <dbReference type="GeneID" id="19126276"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8352"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_2_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008106">
        <property type="term" value="F:alcohol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000158">
        <property type="entry name" value="Zinc-binding alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="20"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC41988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="357" mass="38137" checksum="695940903EB0FAE2" modified="2014-04-16" version="1">MATDTKFEGWLGKDKESVKGKMEWGQFEPKKWTEDDVDIEVSHCGICGSDLHMLSSGWAPTPYPCVVGHEIIGKAVKVGKNVKHVKEGDRVGVGAQARSCLQPDCPECSNGIENHCSRGNVSTYGSIYPGDEGKSYGGYAKHNRTNGHFVLKIPEGLDSADAAPMLCGGITVYSPLRRFGCGPGKKVGIVGVGGLGHFGVLFAKALGADKVVGISRKAEKRDDVLKLGADSYIATDEDADWAKHNAGTLDLIISTVSSVKMPLDGYLGLLGTHGTLVQVGAPDKGELPPINAFTLLTRGISVAGSGIGAPWEIKEMLELAAEKKIKPWVQKRPMSDANNAIIDMEAGKARYRYVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWZ1</accession>
    <name>W6YWZ1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689544.1">
        <property type="nucleotide sequence ID" value="XM_007691354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWZ1"/>
    <dbReference type="STRING" id="930090.W6YWZ1"/>
    <dbReference type="GeneID" id="19125042"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6686"/>
    <dbReference type="eggNOG" id="ENOG502SKSN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007381_0_0_1"/>
    <dbReference type="OrthoDB" id="5341924at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="991" mass="111066" checksum="C9B7DDE771ADE475" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX60</accession>
    <name>W6YX60_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_27594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964014">
        <property type="protein sequence ID" value="EUC43982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689473.1">
        <property type="nucleotide sequence ID" value="XM_007691283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX60"/>
    <dbReference type="GeneID" id="19121146"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27594"/>
    <dbReference type="HOGENOM" id="CLU_1331729_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="206" mass="22437" checksum="B20FFA12FA3D8670" modified="2014-04-16" version="1">MPGSGLAPNLNQRQADDRRNLQRRVRVNGAVEGRRTSSRRWSGGWGRAGKGRAGSDECDVLDESDCRYQCDQSCTKAGDRLKGAARGRGSEGAKLRGKKSEGGFQQQKQLAVKRLFRPLGHSQKKEGPFQPAACAARRQTGSQQKSEFGYILVKSRAGEAKKSRLVPPTRWLIGFSRACGSQLPPTCGESDTQFGFLASTSLTHTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX93</accession>
    <name>W6YX93_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Presequence protease, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Pitrilysin metalloproteinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_9924</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running. Preferentially cleaves the N-terminal side of paired basic amino acid residues. Also degrades other unstructured peptides. May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer and homodimer; homodimerization is induced by binding of the substrate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M16 family. PreP subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964193">
        <property type="protein sequence ID" value="EUC40144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693336.1">
        <property type="nucleotide sequence ID" value="XM_007695146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX93"/>
    <dbReference type="STRING" id="930090.W6YX93"/>
    <dbReference type="MEROPS" id="M16.013"/>
    <dbReference type="GeneID" id="19129426"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9924"/>
    <dbReference type="eggNOG" id="KOG2019">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009165_0_0_1"/>
    <dbReference type="OrthoDB" id="10250783at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000020">
        <property type="entry name" value="Mitochondrial presequence protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000009">
        <property type="entry name" value="Presequence protease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000011">
        <property type="entry name" value="Presequence protease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055130">
        <property type="entry name" value="PreP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF13">
        <property type="entry name" value="PRESEQUENCE PROTEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08367">
        <property type="entry name" value="M16C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22516">
        <property type="entry name" value="PreP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16C associated" evidence="16">
        <location>
            <begin position="494"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1017"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1037" mass="115821" checksum="E517F85708982CFC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYE5</accession>
    <name>W6YYE5_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_98280</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYE5"/>
    <dbReference type="STRING" id="930090.W6YYE5"/>
    <dbReference type="GeneID" id="19129225"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98280"/>
    <dbReference type="HOGENOM" id="CLU_1901157_0_0_1"/>
    <dbReference type="OrthoDB" id="3556572at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="134" mass="15673" checksum="B4E879995F896780" modified="2014-04-16" version="1" fragment="single">LAIGRAELRSLSIYSLILTSPEHLKQLYLKVYPDYDSYQLTSYPNPDTWGSRQIKQKATCDLMLRLWQDFVQKRTLEQIEVTFVSPGGSTKIWYYIVSPKCHKRASDRIWKSKVEVQMREEGTDYDPATFDPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYN3</accession>
    <name>W6YYN3_COCMI</name>
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        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_102880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EUC42678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYN3"/>
    <dbReference type="GeneID" id="19118178"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102880"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="462"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="71"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="518" mass="57323" checksum="254DD9304F03E1A9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ15</accession>
    <name>W6YZ15_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nuclear protein DGCR14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_102514</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964048">
        <property type="protein sequence ID" value="EUC42818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690673.1">
        <property type="nucleotide sequence ID" value="XM_007692483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ15"/>
    <dbReference type="STRING" id="930090.W6YZ15"/>
    <dbReference type="GeneID" id="19118094"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102514"/>
    <dbReference type="eggNOG" id="KOG2627">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024820_0_0_1"/>
    <dbReference type="OrthoDB" id="19679at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019148">
        <property type="entry name" value="Nuclear_protein_DGCR14_ESS-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12940">
        <property type="entry name" value="ES-2 PROTEIN - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12940:SF0">
        <property type="entry name" value="SPLICING FACTOR ESS-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09751">
        <property type="entry name" value="Es2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="302"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="353"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="53099" checksum="8F45271D1F4006A6" modified="2014-04-16" version="1">MSASNSTALTKRNASDALMPPPPAPKRIKRPSVVLDEDTYVSAISHIIRRDFFPGLAEADAQREYLNAVESKNRAWIREAGKKLTQVMTPVPNGQRKMAARTRFEKAGGSGDKTPSVWGADTPTTVAESETEEVDQDLGKLDHVDLDMSLGAFQAKYTSEDQESFSQIVDKQNKARFEKNVWLRQGNMYASKQRIAQQKVIEARAAESKGKELVLSTRPSQDLDERLAAPTGHRHTAINSLMFGPESVEQWAPTRAQVAESKSLAPPKQVVYNNTRLPIPDTEPQPQRPSSPTLSAVRDAIAGRPRLNPSEGGYTGSETPRVNGYAFVDAHPPSDDSDSEADAPTDLLERYGLNSTNKVSPFTMNESSSREKMLHRMVDKINANRSQSNGTNHTSKPSSSSLPSTGSRLGIFTSQTPRFKGAGPATPGVAVGQTPGRKGKADLTPAAQRLFERVGGATPRQNSSSAGGFGGREGKEWTPTPRVKRRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZQ8</accession>
    <name>W6YZQ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Extracellular metalloproteinase</fullName>
            <ecNumber evidence="13">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Fungalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_9208</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the peptidase M36 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="13"/>
    <dbReference type="EMBL" id="KI964124">
        <property type="protein sequence ID" value="EUC41029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692454.1">
        <property type="nucleotide sequence ID" value="XM_007694264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZQ8"/>
    <dbReference type="MEROPS" id="M36.001"/>
    <dbReference type="GeneID" id="19128005"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9208"/>
    <dbReference type="eggNOG" id="ENOG502QTDC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012703_3_0_1"/>
    <dbReference type="OrthoDB" id="3227768at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 13" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009369599" description="Extracellular metalloproteinase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="14">
        <location>
            <begin position="86"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="434"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC41029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="641" mass="69769" checksum="F1435C44CDBD92B5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0B7</accession>
    <name>W6Z0B7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Structure-specific endonuclease subunit SLX4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SLX4</name>
        <name evidence="11" type="ORF">COCMIDRAFT_37104</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a heterodimer with SLX1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9">Phosphorylated in response to DNA damage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SLX4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963990">
        <property type="protein sequence ID" value="EUC45142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688341.1">
        <property type="nucleotide sequence ID" value="XM_007690151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0B7"/>
    <dbReference type="STRING" id="930090.W6Z0B7"/>
    <dbReference type="GeneID" id="19123182"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37104"/>
    <dbReference type="eggNOG" id="ENOG502S832">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_302495_0_0_1"/>
    <dbReference type="OrthoDB" id="5349119at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033557">
        <property type="term" value="C:Slx1-Slx4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03110">
        <property type="entry name" value="Endonuc_su_Slx4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027784">
        <property type="entry name" value="Slx4_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018574">
        <property type="entry name" value="Structure-sp_endonuc_su_Slx4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09494">
        <property type="entry name" value="Slx4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="13"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="104"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="382"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="616"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="706"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="826"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
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            <begin position="746"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="826"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="997" mass="109640" checksum="F0383AC19C0ED8CC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0K4</accession>
    <name>W6Z0K4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_95995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC45277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
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    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="60601" checksum="730808A2BB4FB1C4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z187</accession>
    <name>W6Z187_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_95442</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates. The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site. Shows a broad primary substrate specificity. Favors hydrophobic residues at the P1 and P1' positions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase A1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC45522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689823.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19128659"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95442"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_0_1_1"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06097">
        <property type="entry name" value="Aspergillopepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Endothiapepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000026">
        <property type="entry name" value="Endothiapepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034163">
        <property type="entry name" value="Aspergillopepsin-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF2">
        <property type="entry name" value="ASPERGILLOPEPSIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889606" description="Peptidase A1 domain-containing protein" evidence="9">
        <location>
            <begin position="20"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="10">
        <location>
            <begin position="97"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00055396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="406" mass="42676" checksum="72732253A9A29477" modified="2014-04-16" version="1">MPSIVNLTAALALAGSVAANPIQLDKRGTFSINQVPHSTHLKNGPADKIKALRKYGKPVPESLVKAAENRANTVVVEATSSSGSVTASPNDQYDASYLSPVTIGTKTFHLDFDTGSSDLWVYSSLQPQSQLSGRSYYTVDPSKAKSGYTWKISYGDGSGASGKVYADKVTVGPITATSQAVEAAQSVSASFSSDANTDGLLGLAMSSINTVKPVQQTTFFDTVKSQLAKPVFSVNLKYHAAGSYDFGFIDSSKYTGAITYVNVDDSQGFWGFSATGYAVGTKTTSASIDAIADTGTSLVYVDDSILRTYYAQVRGAKVDSQQGGYVFPCSSTLPDFSIVVGGVKQTIPGKYINFAPNGDGTCFGGLQSSSDLGLSIFGDIFLKSKYVIHEMGSNGPRLGFAQQSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1J2</accession>
    <name>W6Z1J2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_40301</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="6"/>
    <dbReference type="EMBL" id="KI964098">
        <property type="protein sequence ID" value="EUC41524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691948.1">
        <property type="nucleotide sequence ID" value="XM_007693758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1J2"/>
    <dbReference type="STRING" id="930090.W6Z1J2"/>
    <dbReference type="GeneID" id="19123857"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40301"/>
    <dbReference type="eggNOG" id="ENOG502QPSU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030903_0_1_1"/>
    <dbReference type="OrthoDB" id="4699125at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000005">
        <property type="entry name" value="Phospho-2-dehydro-3-deoxyheptonate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF18">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, PHENYLALANINE-INHIBITED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="7">
        <location>
            <begin position="56"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="374" mass="40723" checksum="1FF06ECC3EFF4689" modified="2014-04-16" version="1">MSFHIENAAVGDPHNSEDWRIRGYNPLTPPDLLQSEIPQTAKSRDTVLKARDEAVAIVQGKDAQKRLLVVIGPCSIHDPAAALDYCDRLLKLKEKYQDDLLIVMRSYLEKPRTTVGWKGLINDPDIDNSFKINKGLRISRQLFADLTEKGMPLASEMLDTISPQFLADMFSVGAIGARTTESQLHRELASGLSFPVGFKNGTDGTLDVAIDAIGSAKHPHHFLSVTKPGVVAIVGTIGNDDCFIILRGGKKGTNYDAKSVKEAREKLESKGMNSRLMVDCSHGNSEKNHMNQPKVARAIAEQIEAGETAIMGVMIESNIKAGTQKVPKEGKAGLEYGMSITDACIDWETTETVLEDLAAAVSKRRTLLGQNGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z202</accession>
    <name>W6Z202_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_6645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964014">
        <property type="protein sequence ID" value="EUC44015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689472.1">
        <property type="nucleotide sequence ID" value="XM_007691282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z202"/>
    <dbReference type="GeneID" id="19125032"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6645"/>
    <dbReference type="eggNOG" id="ENOG502QQ2V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059017_0_0_1"/>
    <dbReference type="OrthoDB" id="5549748at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07600">
        <property type="entry name" value="BAR_Gvp36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018859">
        <property type="entry name" value="BAR_dom-cont"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10455">
        <property type="entry name" value="BAR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="35160" checksum="2D6428F44F1E1C65" modified="2014-04-16" version="1">MENLGKISAFGKNISATFTPWAARTQQYVKEQVGNVEDKTQLPPDYIELEKRVDALKKVHTTMLQVTSQYANEAYDYPANIRESFNDLGRTVAEKVNLLSSATSPAEAQAALTAPPSAKPQPKTFSHAVARAALNASHMLTSEQTSSGEDPLATALEKYAIASEKVGEARLAQDAQIQSRFLAGWSTTLNTNIQFATRARKAVENSRLTLDATKANARGPAFTLPGQPAKKDNLDDDLTEEARAKIEQAEDEFVGQTEEAVGVMKNVLDTPEPLRNLADLIAAQLEYHKKAYEILSELAPVVEQLQVEQEASYRRAREEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z253</accession>
    <name>W6Z253_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_4970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687599.1">
        <property type="nucleotide sequence ID" value="XM_007689409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z253"/>
    <dbReference type="STRING" id="930090.W6Z253"/>
    <dbReference type="GeneID" id="19124447"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4970"/>
    <dbReference type="eggNOG" id="ENOG502RZFD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_429578_0_0_1"/>
    <dbReference type="OrthoDB" id="5404323at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="637" mass="69885" checksum="7CE72E01A964F371" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2C9</accession>
    <name>W6Z2C9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Leptomycin B resistance protein pmd1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_94291</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687590.1">
        <property type="nucleotide sequence ID" value="XM_007689400.1"/>
    </dbReference>
    <dbReference type="GeneID" id="19128420"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94291"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000967">
        <property type="entry name" value="ABC multidrug transporter mdr4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000057">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF18">
        <property type="entry name" value="ABC TRANSPORTER B FAMILY MEMBER 11-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="733"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="775"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="848"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="878"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="955"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="100"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="417"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="735"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1078"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="669"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="686"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC45907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1321" mass="144324" checksum="614B0FE22647EAA5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2E6</accession>
    <name>W6Z2E6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_105221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964086">
        <property type="protein sequence ID" value="EUC41799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691699.1">
        <property type="nucleotide sequence ID" value="XM_007693509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2E6"/>
    <dbReference type="GeneID" id="19118650"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105221"/>
    <dbReference type="eggNOG" id="ENOG502S90D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096188_0_1_1"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02231">
        <property type="entry name" value="cupin_BLL6423-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047142">
        <property type="entry name" value="OryJ/VirC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156:SF3">
        <property type="entry name" value="CUPIN 2 CONSERVED BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="86"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="182" mass="20018" checksum="534D47033A1806B9" modified="2014-04-16" version="1">MAHVGALPKIHRYITSHNDEGKAIFSNAFDDESKMKPNSDGIAFALSYTTKGFPVDMNKDKDLGVYGDYLDDAPGLVVSGGTVLRHVDIPPATECTMHRTVSLDYGCVLEGEIECLLDSGEKRFMKRGDVAIQRGTMHQWINHSPTEWCRMLFVLQECQPLKLGGETVGEELAGMAGVRPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2P1</accession>
    <name>W6Z2P1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_99377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964014">
        <property type="protein sequence ID" value="EUC43998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689496.1">
        <property type="nucleotide sequence ID" value="XM_007691306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2P1"/>
    <dbReference type="GeneID" id="19129460"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99377"/>
    <dbReference type="eggNOG" id="ENOG502QW7T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050100_0_0_1"/>
    <dbReference type="OrthoDB" id="3366093at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005034">
        <property type="term" value="F:osmosensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006972">
        <property type="term" value="P:hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001402">
        <property type="term" value="P:signal transduction involved in filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039295">
        <property type="entry name" value="MSB2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778:SF1">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="270" mass="27881" checksum="27897815D6AD8E69" modified="2014-04-16" version="1">MIAPPGGVPPAIQQNTFMGQVCFKWPLNYPFVSANDGGQQIFHYLPIAIADALNISVSDVKNYGLKPLNTMEYSGFITTVAMFTIPADLQTKLALQLRNPASALWNNEDSTVNDLTNLINTACPLAAGNLPADGPSGGSSGEGDASSPNGGSGGGGAMGGDIGASRKVNSTSAIVASSAIVGAIAYGAAMFFVARRYRNKRMAHQRSSSVPSTGRNTFGSIPGGAAAWMHGARNGRMTPGSRGSSASQGRSIRTQQISAPVMAENSLGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3G5</accession>
    <name>W6Z3G5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Adenylosuccinate lyase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_98643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689256.1">
        <property type="nucleotide sequence ID" value="XM_007691066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3G5"/>
    <dbReference type="STRING" id="930090.W6Z3G5"/>
    <dbReference type="GeneID" id="19129302"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98643"/>
    <dbReference type="eggNOG" id="KOG2700">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030949_3_1_1"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01597">
        <property type="entry name" value="pCLME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172:SF2">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenylosuccinate lyase C-terminal" evidence="2">
        <location>
            <begin position="392"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="475" mass="52100" checksum="4B0D17C41CFED6C7" modified="2014-04-16" version="1">MFLLRRAPLRAIPRLNTIRPQRRLLGSVSAIDSVIFRTLFGTDEIRKVFDDKAYIDRCVDAETALARAQSKCNVIPSHIGEVVTSKAREAQLDYDKLRRETEIVGYPIFPLVRQLSASCGDEAGRYVHWGATTQDIMDLASILQMKEGLQIVERTLRSVIKNLEHLSKKHRDTPMAGRTHLQHALPITFGHKCAIWLSGFQRHLERLEQLRDRALMVQFGGAAGSLASLGSGDGGIRVRKEMAKDLGLTDPPITWHVARDGVAEITNYLALVGGSLGKLALDIIIMSSNELSEVSEPFVPHRGASSTMPQKRNPISSEVILAASKILRSNAGLVLDGMVSDFERASGPWHLEWVAVPESFVIAVGALNQADFALSGLVVNPKQMLTNLYSTKGLIVAEAVMMGLAPHVGRSKAHDIVYEACKESIERDTSLLEALQTRSEITDKISTEELSSLCDAKNYLGSCGLMVDEVLAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z457</accession>
    <name>W6Z457_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Large ribosomal subunit protein mL59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_27142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688925.1">
        <property type="nucleotide sequence ID" value="XM_007690735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z457"/>
    <dbReference type="STRING" id="930090.W6Z457"/>
    <dbReference type="GeneID" id="19121069"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27142"/>
    <dbReference type="eggNOG" id="ENOG502S2BX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076154_0_0_1"/>
    <dbReference type="OrthoDB" id="18529at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037507">
        <property type="entry name" value="Ribosomal_mL59"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040922">
        <property type="entry name" value="Ribosomal_mL59_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18126">
        <property type="entry name" value="Mitoc_mL59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL59" evidence="2">
        <location>
            <begin position="15"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="209" mass="23373" checksum="1AEDF06BC044C667" modified="2014-04-16" version="1">MSAPKTVEIAKSLPPRLLRFFQKYPPPALFPDLTSPLSNPSQPTANIISTTPPIDSNTSISEISAPKDTPIPSSAPQNSNIPPEAHQLPYPNPFLPHKNFTTGRWQSPAYGLRKQADLVKLASEHGVVDLLPWTIKKPGEKERQRVERGLQVKGTGEGQKVKGKLWERTLKGRLEMRRQAMLNMPALIQEWKQKGHGRGWKKWPSGKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4I0</accession>
    <name>W6Z4I0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme 1, mitochondrial</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="12" type="primary">PSD1</name>
        <name evidence="14" type="ORF">COCMIDRAFT_4302</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 alpha chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
        <text evidence="12">Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 beta chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686811.1">
        <property type="nucleotide sequence ID" value="XM_007688621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4I0"/>
    <dbReference type="STRING" id="930090.W6Z4I0"/>
    <dbReference type="GeneID" id="19124195"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4302"/>
    <dbReference type="eggNOG" id="KOG2420">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029061_1_1_1"/>
    <dbReference type="OrthoDB" id="4330at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03208">
        <property type="entry name" value="PS_decarb_PSD_B_type1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033661">
        <property type="entry name" value="PSD_type1_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF6">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023505192" description="Phosphatidylserine decarboxylase 1 beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023505191" description="Phosphatidylserine decarboxylase 1 alpha chain" evidence="12">
        <location>
            <begin position="462"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial matrix" evidence="12">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial intermembrane" evidence="12">
        <location>
            <begin position="93"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="212"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="214"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="462"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="462"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="461"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC46647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="516" mass="57567" checksum="958BF2DF3F7990FF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4Q3</accession>
    <name>W6Z4Q3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_97566</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688814.1">
        <property type="nucleotide sequence ID" value="XM_007690624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4Q3"/>
    <dbReference type="STRING" id="930090.W6Z4Q3"/>
    <dbReference type="GeneID" id="19129085"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97566"/>
    <dbReference type="eggNOG" id="KOG0659">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_6_1"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070985">
        <property type="term" value="C:transcription factor TFIIK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07841">
        <property type="entry name" value="STKc_CDK7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037770">
        <property type="entry name" value="CDK7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF0">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="68"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="366"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="74"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR637770-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR637770-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC44708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="417" mass="46526" checksum="A274CF8280296D5D" modified="2014-04-16" version="1">MASPVVLSPRPNPPGAAMSAASKMRTLALPSHTTKPVKSPAPPAPATVAGDGGMDLAEQMNDRVRSQFVMGPRLGEGTYAVVYQAHYRDNPKHIVAIKKIKYNAEYPNGIAPDAIREMQFLFEMSHPNVIKLHDVFSTKEQNLSLVLEHLPLGDLEKLWKNKEITYTKADIKAWMNMLCQGIWFCHENFVLHRDIKGSNALIAADGTIKIADFGLARSFADPGVKMTTMVITRMYRPLELLYGCSHYGGTADMWSIGVLMAELCKRDWFLYSDTDMRQVAVICEKFGTPTEETWPGVTALPYYVAPDKQTGPQGTTAFRQTRPRSWWKQEFPTLGDDGCDFIRGLLTLDPQKRYTARKALEDKWWTNAPRPTKKENLPKEGGGTKAMGEDLKRRGGETPANGRADKVARKLDFGSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z588</accession>
    <name>W6Z588_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_91635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686595.1">
        <property type="nucleotide sequence ID" value="XM_007688405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z588"/>
    <dbReference type="GeneID" id="19127920"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91635"/>
    <dbReference type="HOGENOM" id="CLU_2223012_0_0_1"/>
    <dbReference type="OrthoDB" id="3678684at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="106" mass="12098" checksum="DD69CB3736BC6D7C" modified="2014-04-16" version="1">MPSMGTPSELSCEDGVDHFADFDGTHTPQEDGGRRESVEKRPSCVVSENENDRNDQEVNQSERQHQGGNRISDQGNWMRRIWVWLKKIADTFLARTFRLVLHRGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z678</accession>
    <name>W6Z678_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4Fe-4S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963983">
        <property type="protein sequence ID" value="EUC45495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z678"/>
    <dbReference type="GeneID" id="19123109"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36777"/>
    <dbReference type="HOGENOM" id="CLU_2812150_0_0_1"/>
    <dbReference type="OrthoDB" id="10289112at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889746" description="4Fe-4S ferredoxin-type domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7337" checksum="9D8734BD86C81A99" modified="2014-04-16" version="1">MRFLFGILMLSIGSALAGPVGSDMLSVRDPQTSTGCRGCYHNCNTSYPRGKPRNDCYTGCPRLFQDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6V0</accession>
    <name>W6Z6V0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CBF1-interacting co-repressor CIR N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_34997</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC25 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685998.1">
        <property type="nucleotide sequence ID" value="XM_007687808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6V0"/>
    <dbReference type="STRING" id="930090.W6Z6V0"/>
    <dbReference type="GeneID" id="19122682"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34997"/>
    <dbReference type="eggNOG" id="KOG3869">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025093_0_0_1"/>
    <dbReference type="OrthoDB" id="21123at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022209">
        <property type="entry name" value="CWC25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051376">
        <property type="entry name" value="CWC25_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12542">
        <property type="entry name" value="CWC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="9">
        <location>
            <begin position="10"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="101"/>
            <end position="131"/>
        </location>
    </feature>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z788</accession>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_7123</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">ATCC 44560</strain>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
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    <sequence length="587" mass="67229" checksum="582E434675D403EE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7A7</accession>
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            <taxon>Pleosporales</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF11">
        <property type="entry name" value="CERAMIDE SYNTHASE LAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
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            <begin position="154"/>
            <end position="171"/>
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            <begin position="376"/>
            <end position="395"/>
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    </feature>
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            <begin position="189"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="414"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="480" mass="55513" checksum="F8BA0946A7A72C98" modified="2014-04-16" version="1">MTEPFPPLNGGLPHNPAPQSAPRRRRKSSALGADVPGDVDVPSLATYRSVTPPLHSPVTMDSKSDKSGRRSKRKTTRRYLSKAKRMCIRHTWLLPLVLTLTVISLYLVYPYSSNPLSACLFLSYPLARDDPLIPAHVRADPNAPLHYGKGGRDFAFVGFYTIVLSFTREFCMQRLIRPIALHFGIRNRDKQSRFMEQAYTALYFGIYGPFGIWIMSRTPVWYFNTNGMYEGFPHRTHEAVVKAYYLLQASYWAQQAIVLMLMLEKPRKDFKELVAHHIITVSLIWLSYRFHFTYMGIAVYITHDVSDFFLASSKCLNYIDSPIVTPYFFVFMMVWGYARHYINLKIIWSILTTFKTVGPFELNWETQQYKCWISQYITLGLLASLQAVNLFWGFLICRIAYRFAVYKDMEDDRSEYEPTDEETEAKEKLIKEDATKEKEAKTQMEKVEQMAPVTPAQPNPVKVEQDSIGSRVKQRKSGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7I8</accession>
    <name>W6Z7I8_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_7037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964026">
        <property type="protein sequence ID" value="EUC43539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689935.1">
        <property type="nucleotide sequence ID" value="XM_007691745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7I8"/>
    <dbReference type="STRING" id="930090.W6Z7I8"/>
    <dbReference type="GeneID" id="19125159"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7037"/>
    <dbReference type="eggNOG" id="ENOG502RZZS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038616_0_0_1"/>
    <dbReference type="OrthoDB" id="5578001at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="403" mass="43945" checksum="FD45D281D9BED0E2" modified="2014-04-16" version="1">MPGISEIIPQPDPRELLPPLLACLATAKASKDVPPGLLPLLSPILRQRVQLLSSSEWLPLLSWDQEVASRLPEVIEKIDVEPHPSSGEIEIEEPDEILYRRSDAETLHSRLVLGEYGIIPTYLWCTGGEGGSRWLLAELRGLADAEDGTEWFKHVADANEAGFRRKSGTVKSNGIKIQQAVLEPEVAVEEDEDDGSYWAAYDQTPGRTPQPRRSPAPISNSQTQVGPTQSELEYFARYASEVQPALDAHDPDEESPAAGESTLNGNALSYARGPQTEALNASSLGPNGYDSSIASAHTNGHMNSDGLNGNDSAIYHMSAGQDREIAASALNHPRPSSSASSSSIERLEQKAESSSQAELAIKQHISTDIKSLFRLARASGIDREEFERIIQRELEVLPMLEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7R2</accession>
    <name>W6Z7R2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964272">
        <property type="protein sequence ID" value="EUC39711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693770.1">
        <property type="nucleotide sequence ID" value="XM_007695580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7R2"/>
    <dbReference type="GeneID" id="19119663"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110772"/>
    <dbReference type="HOGENOM" id="CLU_1943071_0_0_1"/>
    <dbReference type="OrthoDB" id="10277851at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="130" mass="14826" checksum="1D5DC127EEC9237D" modified="2014-04-16" version="1" fragment="single">LFKTCVFLIINAAKGIDLPLSLAFSDIIERMEVFFILYIEYESKPKLFSKNSFIFTNKGSCVLDNLIERTGLKVALSILNEPSPSIKPSNQLFVIKTWFSGILKLIRLVFMLFFNSNNLDINSSVNFSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z945</accession>
    <name>W6Z945_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Plectin/eS10 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_4335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686870.1">
        <property type="nucleotide sequence ID" value="XM_007688680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z945"/>
    <dbReference type="STRING" id="930090.W6Z945"/>
    <dbReference type="GeneID" id="19124206"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4335"/>
    <dbReference type="eggNOG" id="KOG3344">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089349_0_1_1"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000025">
        <property type="entry name" value="40S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="64"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="152"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="222" mass="24559" checksum="376856A7144ED4FA" modified="2014-04-16" version="1">MGIEAGGGTKDLDARLGIGGHSASLRLVAHPSVEMPTSGELLLIDLTNQSKHPRVFSQTVKMLIPKADRKAIHEYLFREGVLVAKKDFNLPKHGEIDTKNLFVIKACQSLTSRGYLKTRFSWQYYYYTLTPEGLDYLREWLHLPAEIVPQTHIKQQRSAPPRGMLGGDDRERRGGGRGGRGGDRGEYRRRDQGEKGEGGAPGEFKPEFRGGFGRGRGAAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9I8</accession>
    <name>W6Z9I8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_87235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685052.1">
        <property type="nucleotide sequence ID" value="XM_007686862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9I8"/>
    <dbReference type="GeneID" id="19127014"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87235"/>
    <dbReference type="eggNOG" id="KOG4525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009601_2_1_1"/>
    <dbReference type="OrthoDB" id="74460at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09613">
        <property type="entry name" value="Jacalin_metallopeptidase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033862">
        <property type="entry name" value="Jacalin-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053002">
        <property type="entry name" value="Metalloproteinase_M10B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021917">
        <property type="entry name" value="Unchr_Zn-peptidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21054:SF2">
        <property type="entry name" value="MIP04191P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21054">
        <property type="entry name" value="ZINC METALLOPROTEINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12044">
        <property type="entry name" value="Metallopep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Jacalin-type lectin" evidence="2">
        <location>
            <begin position="627"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="774" mass="86373" checksum="F46ECBB83986E995" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA44</accession>
    <name>W6ZA44_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30502</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964153">
        <property type="protein sequence ID" value="EUC40586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692894.1">
        <property type="nucleotide sequence ID" value="XM_007694704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA44"/>
    <dbReference type="STRING" id="930090.W6ZA44"/>
    <dbReference type="GeneID" id="19121691"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30502"/>
    <dbReference type="eggNOG" id="KOG2456">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023881_0_0_1"/>
    <dbReference type="OrthoDB" id="5596991at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43111">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43111:SF1">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="473"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="2">
        <location>
            <begin position="29"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="506" mass="54250" checksum="2F9B4954DBB23527" modified="2014-04-16" version="1">MSSSPITPEAALEILQATALTARCHNAFFRQKQLKSLHDALRNSSDAIRNAIKQDTHVSDEEATTEVAVVLDLVKEHYASIDVTKELEAEYRITNGKDASNRRVPWGVAYIEPQKSHTPFFSVLSPLSAAVAAGTCVALKLENNLRALPSLLRKLLTEALESDTFLIISSSPPADSLSTYLQVLQETQVAQPTYSQHVSPQGKVIAIVDRTADLATAASHLVTARFAFGGTSPYAPDIILVNEFIKKEFLEHVLQLSFRYLVGSGSLANGSSNPGSNQKSSSSSRISTAFSTLSSSKSWDLTTISSGDNGAVVELSNLSSLPPKSTQPIFAVSAITSLEHAISLVEQDVSPNETLLASYHFGANATAKYLSQFVPAAVSFANSVPFSLLLGPAAPEPSSQIPFDVEKRYTVEHFSRLAPAYVSVPGSQRSLLKVLSGKEGAKVASEMLGQATKEIKEAKRKESIAIGYFEQGIFVGLGVYGIPLLTCIGASLFFGVRAGLRKLAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAK3</accession>
    <name>W6ZAK3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_4003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC47010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686457.1">
        <property type="nucleotide sequence ID" value="XM_007688267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAK3"/>
    <dbReference type="STRING" id="930090.W6ZAK3"/>
    <dbReference type="GeneID" id="19123794"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4003"/>
    <dbReference type="eggNOG" id="ENOG502S4JN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095059_0_0_1"/>
    <dbReference type="OrthoDB" id="5344687at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42089">
        <property type="entry name" value="YALI0F09427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42089:SF1">
        <property type="entry name" value="YALI0F09427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="228" mass="25103" checksum="EF0A0A6AFFE45587" modified="2014-04-16" version="1">MEVQQIRALAFRLRSANLRGVTWACLAKPCANVSVIILNSMNDMKHGGGDPHPLLAQVPLTVSPFISLPTATPLPYSYKSLPSTLPPSVLSQQQQQQQQQNESSPSHHQQQEESTGAYVVSASGTSASPDQILSSCTALQAHLKQLEDDARRTLAQWEDRRRAEDLAEKRRVAPGWLDSGVHILKPEGIDEDKGKEPQQQNLMDLDPQAEQKAKQGEELDRVFGGLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAK8</accession>
    <name>W6ZAK8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_91281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC47015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686517.1">
        <property type="nucleotide sequence ID" value="XM_007688327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAK8"/>
    <dbReference type="STRING" id="930090.W6ZAK8"/>
    <dbReference type="GeneID" id="19127852"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91281"/>
    <dbReference type="eggNOG" id="KOG3168">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076902_4_0_1"/>
    <dbReference type="OrthoDB" id="368909at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06168">
        <property type="entry name" value="LSMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034110">
        <property type="entry name" value="LSMD1_Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF5">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="1">
        <location>
            <begin position="10"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="107" mass="11928" checksum="95A0C93EF0090213" modified="2014-04-16" version="1">MDNEQATFWLSQFIGKNLRIHASDGRVFGGQMKCTDKDRNIILALAHEYRAPSAEAIRKAVEESGNQSASVAWNSRFVGLIVVPGQHIKKIEFEENMLPGQKSTVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBB0</accession>
    <name>W6ZBB0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_73280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="19125252"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_73280"/>
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    <dbReference type="OrthoDB" id="3794025at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="71"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="348" mass="39132" checksum="B771BA8D581A4889" modified="2014-04-16" version="1" fragment="single">QTQPRATHESTGASKSGYSVPPHMRPDFPSSFSRRAEVLSSKQILSSNNVPRYHNNLRYNTHHASRSDIPSEQVVRLNAQLLKAKQELEQERTKNANLRKTIQDAQDEHLEAAFSSILTTLLREQTEALALQSRATAHQRSLDIREKKISQQEAFLVAGQKHIMTKLEQNNSTSMSATHYTHLQQQMELDKQSCIFALESRMAMERQTLTLHAAAQAKREQQYKTLVRQSLEAEFAANHMSNNEAEALAEVRFQRGFDAGKDEGRKERAKEEKEKGYLEGYRACFQAQAALSSLRNGASAEVQGLLDPMGEASLFSMGVRVGRMEAASKIEAKKDVKKHEGADLIDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
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    <name>W6ZBF9_COCMI</name>
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            <fullName evidence="2">Azaphilone pigments biosynthesis cluster protein L N-terminal domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="3" type="ORF">COCMIDRAFT_37401</name>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963997">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007690487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBF9"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_37401"/>
    <dbReference type="eggNOG" id="ENOG502SSTG">
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    <dbReference type="OrthoDB" id="1577640at2759"/>
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    <dbReference type="Gene3D" id="1.20.120.1020">
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    </dbReference>
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        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="774" mass="89321" checksum="A2356623A8BDDBA0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBG7</accession>
    <name>W6ZBG7_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
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    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_35299</name>
    </gene>
    <organism evidence="8 9">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBG7"/>
    <dbReference type="STRING" id="930090.W6ZBG7"/>
    <dbReference type="GeneID" id="19122750"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35299"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="56220" checksum="5F5DF8AEE65292CA" modified="2014-04-16" version="1">MVSFLSLFGALIALVIFRFVAVGVYRIYFHPLSKYPGPKLLAATRIPVHISVAKGSRDKLYQDLHRKYGPIVRIAHNELSFIDAGAWKDIHGHGTKGTAGSLPYKDPIRYAESLNGAPNLINSPDDVHTRQRKIFSPAFSDRALKQQEPLFLKYINQFVSVVKKGIQENPETKFDLVRLFNFTTFDVMGDLTFGEPLHMLDNAEYDPWVSNIFGALKVSSIVALTRFYPLLRKFFVMIAPASLSKKRLNHYNHSTTRVTKRLEKGRDSQGVDLWDLVLSQKEGKGLSRPEMDSNASVFMIAGTETTATLVSGLTYLLLCNPECMAKLSQEIRNEFESTDDMTMERLAALPYFAACVKEAFRIYPPVPLTLPRRTPADGTTICGNFVPPDITVGIPQHAMYMSERNFKRPTEFLPQRWLGDPEFDSDEKACLQPFSIGSRDCVGKNMAYHEIRLLAAKTYYHFDIELCDESKNWIDQPTFILWEKPPLLCKMRSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBW6</accession>
    <name>W6ZBW6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_35005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686000.1">
        <property type="nucleotide sequence ID" value="XM_007687810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBW6"/>
    <dbReference type="GeneID" id="19122684"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35005"/>
    <dbReference type="eggNOG" id="KOG0134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_0_0_1"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="359" mass="39621" checksum="134A1653FDCC4528" modified="2014-04-16" version="1">MSRLFQPLTVGSAGLGHRIAMAPLTRYRMDDEHKATSLNKGTLIISEAVIISKNAISSRNTPGIWSEDQISAWKDITSAVHAKGCIIYCQLWHPGRAASPEVIKENGLRMISSSAVPISPEHETPEEMTEEIIWETIGEYAIAAKNAIAAGFDGVEIHGANGYLPDQFLQSTCNQRTDGWGGSIEKRSRFLLEVTKMVAAAVGAEKTAVRLSPYSDFNAMLMDEPEPTFSHVLEELKPFGLGYLHLIEARITGNDDSECGGQKTVSWMIEQWNNTTPVVLAGGFLPDSAKHAVDETYKGYDVIIAFGRYFVANPDLVFRVKESVPLAKYDRSVFYTPKTPVGYVDYPHSQQYLQAMAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC25</accession>
    <name>W6ZC25_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-galactose transporter homolog 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_84713</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684101.1">
        <property type="nucleotide sequence ID" value="XM_007685911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC25"/>
    <dbReference type="STRING" id="930090.W6ZC25"/>
    <dbReference type="GeneID" id="19126516"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84713"/>
    <dbReference type="eggNOG" id="KOG1581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036019_0_2_1"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005459">
        <property type="term" value="F:UDP-galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005460">
        <property type="term" value="F:UDP-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120112">
        <property type="term" value="P:UDP-glucose transmembrane transport into endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC49352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="411" mass="44782" checksum="FFB2DC08F31C5011" modified="2014-04-16" version="1">MAQAVRRKVNETNGHAHHRLDDAVHSIEQKLEEQAELHARNPQEQKEAGLFQLVICVAGIYGSFMTWAWIQERLTTTTHGPRNERFTYSIFLNTIQSAFAAITGLIYLFLSAKKDPRTGVRTVAPIFPSRSILLPLLGIALTSSLASPFGYASLKHIDYVTFILAKSCKLLPVMFLHISLFQKRYPLYKYAVIGFVTLGVAVFTLYSPSTAKKAAKKNGAVNADASQTVGLVLLGVNLLFDGLTNTVQDHIFTSFKGFTGPQMMCAQNIMSTALTVSYLLITPLLASTPLASSLGLATSELSDALGFVAKYPAVGADVLMFSACGAIGQVFIFHTLAHFSSLLLVTVTVTRKMLTMVWSVWWFGHEITNMQWVGVGLVFGGIGAEAAMGRREKAKKAAAKKAELEAAAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCG9</accession>
    <name>W6ZCG9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_5615</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="KI963990">
        <property type="protein sequence ID" value="EUC45124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688323.1">
        <property type="nucleotide sequence ID" value="XM_007690133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCG9"/>
    <dbReference type="STRING" id="930090.W6ZCG9"/>
    <dbReference type="GeneID" id="19124671"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5615"/>
    <dbReference type="eggNOG" id="ENOG502SJT6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020817_0_1_1"/>
    <dbReference type="OrthoDB" id="412382at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF1">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE CELB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887368" description="Glucanase" evidence="10">
        <location>
            <begin position="17"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="414" mass="45049" checksum="519C4752229AADB7" modified="2014-04-16" version="1">MAPLFFAATLLGLASAQTMGTTPEVHPKLSTWKCTKAGGCKMLDTSIVIDSLRHKVHPKSDPSATSSCGDRNNPLNLTVCPDKATCAQNCVIEGIQDYSTQAVFTDGGKLRLDMFNPSGEYMSPRVYLLGEDKVNYEMLQLNGQEFSFDVDMSKLPCGMNSALYLNEMKADGGRSKLNPTGANMGWGYCDAQCSVKPFLDGEANIDKEGACCNEMDIWEANSRANQIAPHVCAKEGVIKCTGDDCGVSGVCGKTGCGDNAYNFRNSKDFYGPGLKVDTTRPFTVVTQFPEKYGVLQAIIRKYVQDGVVTENAMSNVTMDQVWCSAQARAKEYNKFGGHKTMGDALARGMVLTFSLWWDKNGGMQWLDGGLNGPCSPAEDFPDIIQQKVKNPTVTFSEIKWGEIGSTFGTNQTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCN8</accession>
    <name>W6ZCN8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial glycine transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Solute carrier family 25 member 38 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_89848</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>glycine(in) = glycine(out)</text>
            <dbReference type="Rhea" id="RHEA:70715"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685963.1">
        <property type="nucleotide sequence ID" value="XM_007687773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCN8"/>
    <dbReference type="STRING" id="930090.W6ZCN8"/>
    <dbReference type="GeneID" id="19127560"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89848"/>
    <dbReference type="eggNOG" id="KOG0766">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_0_3_1"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015187">
        <property type="term" value="F:glycine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904983">
        <property type="term" value="P:glycine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000103">
        <property type="entry name" value="Mitochondrial glycine transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03064">
        <property type="entry name" value="SLC25A38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030847">
        <property type="entry name" value="Hem25/SLC25A38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181:SF3">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="8"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="116"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="222"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC47583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="318" mass="34278" checksum="94A32BCD98514368" modified="2014-04-16" version="1">MSDGGKRPSSYFHFFAGLNSGILSAVLLQPADLLKTRVQQSRSSTLFGTIQSIASGPNPIRQFWRGTLPSTLRTGFGSAIYFSSLNALRHRASLVAAARADVSLRGGEHSSSLPKLSNTANLATGAFARTWAGFVMMPITVLKVRYESNLYSYNSMFSASRDIFRTEGLKGFFAGFGATAVRDAPYAGLYVLFYEQSKRRLSSLASKIEETSGAATKLSSSTSAGINFVSGVAAAGLGTTVTNPFDAIKTRIQLMPDQYGNTIQAGKKMLAEEGVRSLFDGLGIRIARKAMSSALAWTVYEELIRRAASLKEVVEDKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD23</accession>
    <name>W6ZD23_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial import inner membrane translocase subunit TIM14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit tim14</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">Presequence translocated-associated motor subunit PAM18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_36915</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TIM14 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963986">
        <property type="protein sequence ID" value="EUC45339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688134.1">
        <property type="nucleotide sequence ID" value="XM_007689944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD23"/>
    <dbReference type="STRING" id="930090.W6ZD23"/>
    <dbReference type="GeneID" id="19123140"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36915"/>
    <dbReference type="eggNOG" id="KOG0723">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_13_3_1"/>
    <dbReference type="OrthoDB" id="240298at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000001">
        <property type="entry name" value="Import inner membrane translocase subunit tim14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763:SF28">
        <property type="entry name" value="GEO10507P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="J" evidence="14">
        <location>
            <begin position="50"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00067223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00075483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC45339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="105" mass="11554" checksum="CB09E100DF316B96" modified="2014-04-16" version="1">MSAWVWILGAGATAFFGRAALVALRRSGGGAGALGRSYYKGGFEPKMTRREASLILELPERGITKELLRKKHRSLMLLNHPDRGGSPYLATKVNEAKELLEKEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD87</accession>
    <name>W6ZD87_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_84004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683823.1">
        <property type="nucleotide sequence ID" value="XM_007685633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD87"/>
    <dbReference type="GeneID" id="19126374"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84004"/>
    <dbReference type="HOGENOM" id="CLU_3055894_0_0_1"/>
    <dbReference type="OrthoDB" id="3685950at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="64" mass="7457" checksum="C99C80FA082A5A46" modified="2014-04-16" version="1">MTERRCTRFASAFNKASTTALFWLRVSALSFRNLAWRPAYAGNEWHIKCQCYTIRMGTLVMYGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDE5</accession>
    <name>W6ZDE5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683694.1">
        <property type="nucleotide sequence ID" value="XM_007685504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDE5"/>
    <dbReference type="GeneID" id="19126272"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83498"/>
    <dbReference type="HOGENOM" id="CLU_1767736_0_0_1"/>
    <dbReference type="OrthoDB" id="10390369at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="147" mass="17705" checksum="B09D99D34289DE75" modified="2014-04-16" version="1">MTQAKKTRERLSRSRKKERKRKGYRTTESDFFFIRPPPNLSALYTTSNQSQKGPLKPATRSRPNLKRRWKRVQEICRYGASHQKTHPVCRPWHATCQYQYPKQRVHLLRDSGLEQHFVASFPLFRERRLYSHSCTEKNKDMNLQKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDK1</accession>
    <name>W6ZDK1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_5253</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687915.1">
        <property type="nucleotide sequence ID" value="XM_007689725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDK1"/>
    <dbReference type="STRING" id="930090.W6ZDK1"/>
    <dbReference type="GeneID" id="19124546"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5253"/>
    <dbReference type="eggNOG" id="KOG0337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_5_0_1"/>
    <dbReference type="OrthoDB" id="10261375at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17959">
        <property type="entry name" value="DEADc_DDX54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000865">
        <property type="entry name" value="ATP-dependent RNA helicase DDX54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012541">
        <property type="entry name" value="DBP10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033517">
        <property type="entry name" value="DDX54/DBP10_DEAD-box_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF8">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08147">
        <property type="entry name" value="DBP10CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01123">
        <property type="entry name" value="DBP10CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="108"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="346"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="602"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="797"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="602"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="641"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="677"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="822"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC45534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="891" mass="99060" checksum="BEE7EB88B464D786" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDV1</accession>
    <name>W6ZDV1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_8645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964091">
        <property type="protein sequence ID" value="EUC41681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691797.1">
        <property type="nucleotide sequence ID" value="XM_007693607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDV1"/>
    <dbReference type="STRING" id="930090.W6ZDV1"/>
    <dbReference type="GeneID" id="19126857"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8645"/>
    <dbReference type="eggNOG" id="KOG1188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037323_3_1_1"/>
    <dbReference type="OrthoDB" id="25131at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039328">
        <property type="entry name" value="WDR89"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="158"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="348"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="379" mass="41432" checksum="A8EB34826D5A2266" modified="2014-04-16" version="1">MAPFNEIASTDAGFSAGSYIYKIISTSPRQDPLTYSLTDQLALISSDDSLRFLTAGLRPDGHVAKAHENITCLERANDAPSNVVATAGRDGLVKFWDKRSKQRVLQIESPHKLISALICDAEKNFVAAGIENPEDGPNSSPVYIWDQRNLSAPLRSYIDSHTDTVTNLSLHPSLPNLLLSSSTDGLINIFDSTQADEDDALYQVINHGSAIAHAGFLYPGTDMYAIGTDETVSFYALQSQKEEEEEPAPRVCGDVREELGCEYVIDLCWIGAQPCIAAGKHSEKQATLTPITKGTNGPLDYAFDLTNATLLAGAHGEEIVRDLFTDIHTQTTYTCGEDCQVRAWKTSDSADLHEGDAAASAKKKRKEKKEKDKARFKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDX2</accession>
    <name>W6ZDX2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoside transporter family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_34402</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685326.1">
        <property type="nucleotide sequence ID" value="XM_007687136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDX2"/>
    <dbReference type="STRING" id="930090.W6ZDX2"/>
    <dbReference type="GeneID" id="19122552"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34402"/>
    <dbReference type="eggNOG" id="KOG1479">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021611_3_0_1"/>
    <dbReference type="OrthoDB" id="46396at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034257">
        <property type="term" value="F:nicotinamide riboside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF88">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01733">
        <property type="entry name" value="Nucleoside_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016379">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01130">
        <property type="entry name" value="DERENTRNSPRT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC48180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="450" mass="49729" checksum="0E9329CB4F1245A6" modified="2014-04-16" version="1">MERLRQMFGREEPEASYEPLQGGSERPDGEHIDAEEQAFSWTDYAVFTLLGVAMLWAWNMFLAAAPYFQRRFESNDNLLRNFQSGILSVSTVGNLGSMIVLTKLQARANYPRRIIASLALNAIVFTLLAISTKLFLNVSVGVYFAFLMVMVMIASLATGLCQNGVFAYVSGFGREEYTQGIMSGQGVAGVLPAITQIISVLSVPKKHHVDGAPQESSTSAFVYFLTATAVSLATLFAFFYLLSRDSSKQRLLRTSYNESPEYDDTDRSERKSVPLTRLLRKLFWLAGAIFTTFAVTMFFPVFTPQVLSVRDPATAPRLFQPAAFIPLGFFFWNIGDLIGRVGPALPALRLTHRPQLLFFLSIARILFIPLYLLCNIGGKGAAIPSDFFYLFIVQLLFGMTNGFLGSNCMMGFAEWVEPDELEAAGGFMSLSLVSGLTTGSFLSFFAAQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE98</accession>
    <name>W6ZE98_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_105070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964083">
        <property type="protein sequence ID" value="EUC41856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691630.1">
        <property type="nucleotide sequence ID" value="XM_007693440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE98"/>
    <dbReference type="STRING" id="930090.W6ZE98"/>
    <dbReference type="GeneID" id="19118627"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105070"/>
    <dbReference type="eggNOG" id="ENOG502S0HA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022730_0_0_1"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF284">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="44"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="498" mass="54199" checksum="7CB97C5909232DE3" modified="2014-04-16" version="1">MEQRASIPVLPPIPNPLPSYWQTPRSPLANVIESETDKPTTPYDYAIIGSGISGAMIAHNLLEKRPGARIVMLEAREVCSGATGRNGGHTKAASYRTYTQHVKTLGKQEALKIARLEYTNIVETHQLAEKLGIDCENKLCNTVDLIYDKLAFETGKTAIQALRNDTEDHEKEVGKAAWYQIHEDTAQVEKQFFVASEFHNATLKEPEKLEGAFEYVAGRVHAYRFTTGILSRCVKKGLQLRTNTTVDSIQPSKKTCNDSIALWDIVTKYTTISAAHVIVASNGYTPYILPELQGAIVPMRGQITVQRPGTATKLPSPLPTTYSFIGRDGYEYMIPRPLPSGGGQHIVIGGGLARLSDGGASEFGIVDDASLNPAISAYLRETLTGYHGKENWGEASEAEAEKRVESEWTGIMGATADGQPFVGEVPGKVGEVPGKKGVWVSAGFNGHGMVLCLKSAEALVSMIEGGGVPAWFPGSFLISKERMEKCRFRGRTDLIGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEH7</accession>
    <name>W6ZEH7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sulphur transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_87808</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685282.1">
        <property type="nucleotide sequence ID" value="XM_007687092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEH7"/>
    <dbReference type="GeneID" id="19127132"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87808"/>
    <dbReference type="eggNOG" id="ENOG502S27S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037802_1_1_1"/>
    <dbReference type="OrthoDB" id="10254418at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046513">
        <property type="entry name" value="DUF6691"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp_TsuA/YedE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30574">
        <property type="entry name" value="INNER MEMBRANE PROTEIN YEDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30574:SF1">
        <property type="entry name" value="SULPHUR TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20398">
        <property type="entry name" value="DUF6691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC48283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="35713" checksum="AC580F04B1F7A8EF" modified="2014-04-16" version="1">MFTPVETTVGALLLHQATSNLLYQNGNILGVSGYLRQLLSAPTKEQAAFFTGMAASYVPLKALGPQLMTVYPVVQLGPKAAMATAAVGALIGWGTKMANGCTSGHMLCGLSRLSGRSATAVALFFPTAMITHHLANPTLSTSVCASDVPCYTPIYPSSEEAVSLLVLAGSIIMAARTIPHLVALATGSDDGTKQQADELPNAARNTTQFFSGLLFALGLQISQMAQPAKVSAFLSFPVLQHWDPSLALVMIFGVLPNLIENQVRDFKKPPSFAERFALPTKTVQDIDKRFLMGAVAFGIGWGLSGVCPGPAVIRAFYQPIWGLLWIGGFWLGGKVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEI5</accession>
    <name>W6ZEI5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_22321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683272.1">
        <property type="nucleotide sequence ID" value="XM_007685082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEI5"/>
    <dbReference type="GeneID" id="19120226"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22321"/>
    <dbReference type="HOGENOM" id="CLU_1343028_0_0_1"/>
    <dbReference type="OrthoDB" id="3690991at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="188" mass="21087" checksum="B412F257D9ED5537" modified="2014-04-16" version="1">MAWRSLDPITTTPAMARSAQLESNLDAPLPRPVLHVYTAHPRLGTSSGPACTTNRQSAALALGPSADPRLQKAHPTTLAIKLAVLDTWQMQPNRTMRLRLVPPRTHLDLPLILTPAPLTLTWPWTWTWTWTPACRCRQVNPRTGERHATIGPPTPKSRQICPSYLRFALIQVPAQERVEWENCCKNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEL5</accession>
    <name>W6ZEL5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_36355</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687514.1">
        <property type="nucleotide sequence ID" value="XM_007689324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEL5"/>
    <dbReference type="GeneID" id="19123002"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36355"/>
    <dbReference type="HOGENOM" id="CLU_591839_0_0_1"/>
    <dbReference type="OrthoDB" id="3691251at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886941" evidence="4">
        <location>
            <begin position="18"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC45949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="449" mass="49945" checksum="8A3AB627D96C4D51" modified="2014-04-16" version="1">MCPLGVLVLAILSSITSNTVFRPHDPHIPNSEVTIGYDISNKSSEGYGVSNSAFDSAVGFAQPGVVADVGVTPTVVVILEEQRIPTRTVCDPAIEPEAGIIYTTIRNTPGHLNSLSSDLVMGLAHTLLLMVYYTTFKPLWRSMFNRAISQFPYAICFWLSIALFAILEPILTFGWNYLHREFHASHEAVMKRLRRSEAKAWGQTILIKALEEAKDHSMLTLEALTASHEHIKTRISEVEEQFLGVSRAVTQQDEDVRAIVRTVTDMVHEQHSIREQVGELSTTLQEEHANHCTCVNRFIHAYGSNIITIGHHADCLQQKVDVLERQNLEQAAEIDALKSAVKRSDEERAAMIGFYRKQKFNNMHVNEYYQKAIAEAPEDQLAPAFMAYMTAMHSQMNATLQGVYRSAGGHSQQSNNYGRPPNGSPGFGSPGLGSSRYGPAGNFPFNQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF51</accession>
    <name>W6ZF51_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_2501</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684799.1">
        <property type="nucleotide sequence ID" value="XM_007686609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF51"/>
    <dbReference type="STRING" id="930090.W6ZF51"/>
    <dbReference type="GeneID" id="19120686"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2501"/>
    <dbReference type="eggNOG" id="ENOG502SYGP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1054356_0_0_1"/>
    <dbReference type="OrthoDB" id="2501249at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070124">
        <property type="term" value="P:mitochondrial translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052837">
        <property type="entry name" value="Mitoribosomal_bS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_bS21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41237">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP21, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41237:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC48635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="30211" checksum="E02AA05DB6600813" modified="2014-04-16" version="1">MASKCLGELMLRSSSTARMPYAHMGKQTWPWICHRGFSHTPTRPAQPTRNDGNDQSYASEGESNRPIIRYISDKVAPEAQSPQQAQPQPTQDETTRTIDSLFSGMPTNRTPPPYMQQNAAPGSKNNRIFGAEFSNATRLRPSRPPGLAFDSMALPDSMLNPNLSNKPSDASSLAVQQEETFSSYPRLNPTYGRTVELDASRGRDIVRGIGMLGSLVARNKVKADFNRQRFHERGGLKRKRLASERWRARFKQGFRDVTGRVTELTRKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFP0</accession>
    <name>W6ZFP0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_103898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964066">
        <property type="protein sequence ID" value="EUC42311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691196.1">
        <property type="nucleotide sequence ID" value="XM_007693006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFP0"/>
    <dbReference type="GeneID" id="19118399"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103898"/>
    <dbReference type="eggNOG" id="ENOG502SZ83">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042325_0_0_1"/>
    <dbReference type="OrthoDB" id="5430111at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="378" mass="42084" checksum="FCD6F485118539AF" modified="2014-04-16" version="1" fragment="single">PPTSSAPTSSYSFRSRNKSKLVYDAKYHPMDDAIRPTQAARRRSAHGENQFCLDADDESEDYAAVYTNAEELDDEESEAEEEPRQGAKNKKRKLTQSRLMSVEPTRRSPRKVSDQRVSYNMNVHPQDEFLEVSSEEEEVVVKKKSKRSKRLHVDDMYSDDGVVVSKSAQRRYSDYVDNTTSDEMEFDGGDAVARTEVDSDDGLITIAGNSITSPVVADPQNGIKRKDSIDSLHLSPGRRCFRHDKDAWPVSSGQPFTIFNEKLAYQLAREAHTASPLNYEHDDKENVTDNDNIDVNPLSSSTAGVSIIPEAQYMPTSEDCELSNHRALINYALYDDPHPQTYGLDGTHCSGTGEGDVFSESMNILASGRGLPLGKSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFQ1</accession>
    <name>W6ZFQ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Dihydroxyacetone kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_33722</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13941"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15773"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.29"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; glycerol fermentation; glycerone phosphate from glycerol (oxidative route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684627.1">
        <property type="nucleotide sequence ID" value="XM_007686437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFQ1"/>
    <dbReference type="STRING" id="930090.W6ZFQ1"/>
    <dbReference type="GeneID" id="19122390"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33722"/>
    <dbReference type="eggNOG" id="KOG2426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017054_6_0_1"/>
    <dbReference type="OrthoDB" id="1724672at2759"/>
    <dbReference type="UniPathway" id="UPA00617">
        <property type="reaction ID" value="UER00669"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050354">
        <property type="term" value="F:triokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019588">
        <property type="term" value="P:anaerobic glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10440:FF:000002">
        <property type="entry name" value="Dihydroxyacetone kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.340:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1180.20:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02361">
        <property type="entry name" value="dak_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF14">
        <property type="entry name" value="DIHYDROXYACETONE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="14">
        <location>
            <begin position="9"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="13">
        <location>
            <begin position="381"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-hemiaminal-histidine intermediate" evidence="11">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="53"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00003264"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004778"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048898"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR612734-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-2"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC48855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="61175" checksum="F8A4FFFCA6D7F3D9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFV7</accession>
    <name>W6ZFV7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Metallo-dependent hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964063">
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        <property type="nucleotide sequence ID" value="XM_007692922.1"/>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC42391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="46552" checksum="B44111E447759BD4" modified="2014-04-16" version="1">MATKNSNEENFPWHLGVYDAHCHPTDTMSSIEIIQNMKARVLTVMATRAEDQDLVTATADKHTIRSADPSQWSREECIVPCFGWHPWFSHQMYLTSDIDPDSSFKEQGNLTGETKIAHYKTALHPSRENPSEEDIQTYLSLPDPTPFSTFLSHTRHHLQQYPYALVGEIGLDRSFRIPESWTGTPDLWCKRDNSLTPGGREGRRLTPFRASPSHQKKIFKLQLQLAAEMNRGVSVHGVQAHGLVLEVLSELWKGHEKQVLSKRERKKRGVDHPAAEAAIEADAEGTSHVGKEKEAKPYPPRICLHSYSGNVSNFKQYLNPAIPAQVFASFSTAINLSDKMDEETPESFAEMVRTVPDHMLLVESDLHTAGEEMDRRLEDIVRRICKIKGWELEDGVAQLGKNWRVFAFGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGG3</accession>
    <name>W6ZGG3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PRP3-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_103122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964056">
        <property type="protein sequence ID" value="EUC42586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690910.1">
        <property type="nucleotide sequence ID" value="XM_007692720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGG3"/>
    <dbReference type="STRING" id="930090.W6ZGG3"/>
    <dbReference type="GeneID" id="19118228"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103122"/>
    <dbReference type="eggNOG" id="KOG2769">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015750_2_1_1"/>
    <dbReference type="OrthoDB" id="10264544at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24162">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013881">
        <property type="entry name" value="Pre-mRNA_splic_Prp3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027104">
        <property type="entry name" value="Prp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010541">
        <property type="entry name" value="Prp3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212">
        <property type="entry name" value="U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08572">
        <property type="entry name" value="PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06544">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor 3" evidence="7">
        <location>
            <begin position="134"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Small nuclear ribonucleoprotein Prp3 C-terminal" evidence="6">
        <location>
            <begin position="367"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="81"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="57118" checksum="576210C1D1CCE565" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGN1</accession>
    <name>W6ZGN1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Han J."/>
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                <person name="Grimwood J."/>
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        </source>
    </evidence>
    <sequence length="504" mass="57423" checksum="B99F308CF469F30B" modified="2014-04-16" version="1">MCRFTIATLECGHPQEDHVDTYGCPYFQRSNLHCDRDNPNNKDRFTIKTWDREGICNRCLSVARKREEEAIEREQKKYDEQRRREAKEREEELRRGEREVLERGHRQEEERLAEKKRREEAQRAQERQKWASEERTREVERKSKEEYERQIQLQMDKDMEFMMAKSREEAERREREEEEEIQRALAESARLIRSERSYQEDQMSSGSREQNGGRIESWIESTSRTTTTTTVNNHSSGNNHSNSYSNNHNSSNSYNNNNNNHNHNSSNSHNSNSSNYPQKSSSPPSPPATPPTRKATSPPPPPPLPVTAPRSPVNKSTARAPPPPPPAPKPAAPAKEINYSLPAVGDQKIGRFRLGSRAVPVHESQDIPETPIAPAKPIAPTTPAPMVRLGGAIPVSDVPIVREIKGQVKPVPSAMENARPALPLRKPSVSRKGPPPPVPNRDGRDPQLEAMLAKRRAWEPEEDEGATITPPRSPSKGQTPPARRMTQNEFDTKRKMGWKNNEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI37</accession>
    <name>W6ZI37_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964037">
        <property type="protein sequence ID" value="EUC43166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690290.1">
        <property type="nucleotide sequence ID" value="XM_007692100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI37"/>
    <dbReference type="GeneID" id="19121283"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28310"/>
    <dbReference type="HOGENOM" id="CLU_676124_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="407" mass="43497" checksum="7834BAB6E7BE8BDA" modified="2014-04-16" version="1">MPTNTERLACSESRDTEIRVEQLVRVASHSTTPQGRVVDEGSAKEEQATGGPGKPSYGYGEGRDRVAGSSSGWMSCEWMDGWTGGRGMDAEGRPCVCHSRAEQGTAGQSRLGRMILCEWAVCRPLLGAGKSASVAIGFHDASGCQQRSQVAAKSTAWRTVRANADGPGRSNTHHHHSPTTTQPPGDDETRRDDVKMARLHVRTRTWPPPPSQALGWGWCWCWWLWAEAYQHGSRLRRADVAVGAGENIHNHDKTTSDDKRRQATASPIAAAHARPGQACKSRRASVQVAAGSTVPNPRVAWNRVIGGPSSSLSRRVPIYLSCTCLPLSSKVDCSLAMAVASCRDAYDASLPWPRGGVGCMLPRVPSRVLAPAAAPAAAALLSAHIPIAVLLLPSQTLVGVFMPSCCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIA1</accession>
    <name>W6ZIA1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_1543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683719.1">
        <property type="nucleotide sequence ID" value="XM_007685529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIA1"/>
    <dbReference type="STRING" id="930090.W6ZIA1"/>
    <dbReference type="GeneID" id="19119890"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1543"/>
    <dbReference type="eggNOG" id="ENOG502S19W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005247_1_1_1"/>
    <dbReference type="OrthoDB" id="410701at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="958" mass="108777" checksum="D2E9E7C94DFEC157" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIB7</accession>
    <name>W6ZIB7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_84007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683787.1">
        <property type="nucleotide sequence ID" value="XM_007685597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIB7"/>
    <dbReference type="STRING" id="930090.W6ZIB7"/>
    <dbReference type="GeneID" id="19126375"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84007"/>
    <dbReference type="eggNOG" id="ENOG502S1B6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019843_0_0_1"/>
    <dbReference type="OrthoDB" id="5210591at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF59">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="362" mass="39951" checksum="D34C9BCEB0AD4370" modified="2014-04-16" version="1">MSRGTYAVKPVRSSTSTSSSSTSSSTSSLSRASIQTTVTTVDTSSIQRLIRTVYRSSKITVQQVEVIQGYLGQIYVTRLADGSSLVLKCPPAHNVRLLRHEKHILDTERKTLEMIREYTRIPVPQLITFDTHSSTLGRPFLLMSHIPGRRLSELAPYLTPSERNAIDHTLGMHIGSLTALSAPQFGLAHRVFAKKGSTTWREAFLGLLESMLRDAEDMLVNLHSESIRYWIGKHAHHLDKVTEPRLVAPNACNADNVLLDEHTKHVVGLVGFSNIIWGDPLMSGGMADASEAFLTGLGECAPRTTTTTTIGSSSSAQVRIMIYRIYRATLRLVAHHYRLHDGTDELDARRELSAALNLLAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIM8</accession>
    <name>W6ZIM8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 78 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_90663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686279.1">
        <property type="nucleotide sequence ID" value="XM_007688089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIM8"/>
    <dbReference type="GeneID" id="19127730"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90663"/>
    <dbReference type="eggNOG" id="ENOG502QVGI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007933_1_0_1"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
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            <dbReference type="Pfam" id="PF17390"/>
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    </evidence>
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            <dbReference type="EMBL" id="EUC47239.1"/>
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    </evidence>
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</entry>
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            <fullName evidence="6">AB hydrolase-1 domain-containing protein</fullName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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    </dbReference>
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            <position position="1"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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            <fullName evidence="2">LsmAD domain-containing protein</fullName>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="930090.W6ZJ80"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="2275718at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045117">
        <property type="entry name" value="ATXN2-like"/>
    </dbReference>
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        <property type="entry name" value="LsmAD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025852">
        <property type="entry name" value="SM_dom_ATX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854">
        <property type="entry name" value="ATAXIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854:SF7">
        <property type="entry name" value="ATAXIN-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06741">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SM-ATX"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LsmAD" evidence="2">
        <location>
            <begin position="258"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="733"/>
        </location>
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            <end position="841"/>
        </location>
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            <end position="986"/>
        </location>
    </feature>
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        <location>
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            <end position="1076"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
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            <end position="79"/>
        </location>
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        </location>
    </feature>
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            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        <location>
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            <end position="673"/>
        </location>
    </feature>
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        <location>
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            <end position="708"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1057"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01272"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1076" mass="115866" checksum="E52A853F2EB09585" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJK1</accession>
    <name>W6ZJK1_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="930090.W6ZJK1"/>
    <dbReference type="GeneID" id="19119804"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1163"/>
    <dbReference type="eggNOG" id="KOG0837">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029566_1_1_1"/>
    <dbReference type="OrthoDB" id="5419235at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="259" mass="28015" checksum="0289A33B26A93F63" modified="2014-04-16" version="1">MAGTVHPLRTLDSELTMPADLNSNNSFDSGASLMSNFNNGGFSLDSVSAFTAINDPSVAAGSTRTVSPKDIFNDAFGSAPPSTAFTNLTSPDIGDSPFINDSFECSPMFNGEPNMTDTSDWFSLFPEQETKVPDNVYTPAISMPLERTISSQSMERSGSSSTGSPIVLDSYTRRKSSVTNSPAINGVSKSRRRKGPLPSITVDPNDKVALKRARNTLAARESRQRKFDHVSTLEQRNSELQAEVEKWKSIAMAHGYSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK21</accession>
    <name>W6ZK21_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_99487</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964015">
        <property type="protein sequence ID" value="EUC43941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689527.1">
        <property type="nucleotide sequence ID" value="XM_007691337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK21"/>
    <dbReference type="GeneID" id="19129478"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99487"/>
    <dbReference type="eggNOG" id="ENOG502QTP8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005757_0_0_1"/>
    <dbReference type="OrthoDB" id="435520at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="7">
        <location>
            <begin position="510"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="197"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="653"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="869" mass="96077" checksum="7659B62A6D369E98" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK44</accession>
    <name>W6ZK44_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Centromere protein S</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_32268</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TAF9 family. CENP-S/MHF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683027.1">
        <property type="nucleotide sequence ID" value="XM_007684837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK44"/>
    <dbReference type="STRING" id="930090.W6ZK44"/>
    <dbReference type="GeneID" id="19122061"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32268"/>
    <dbReference type="eggNOG" id="ENOG502S7WI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100369_2_0_1"/>
    <dbReference type="OrthoDB" id="1872155at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071821">
        <property type="term" value="C:FANCM-MHF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22919">
        <property type="entry name" value="HFD_CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029003">
        <property type="entry name" value="CENP-S/Mhf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980:SF0">
        <property type="entry name" value="CENTROMERE PROTEIN S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980">
        <property type="entry name" value="CORTISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15630">
        <property type="entry name" value="CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="101"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="14862" checksum="C4F123F275A026BA" modified="2014-04-16" version="1">MASNDAEAEREERLKSALWYAIGQFVDDKSLESDLNATPQFIGALTELVYTQIANTARDLEVFSKHAGRKTINPDDVLLLGRRNEQLQAMLEKELEEIRAAEGRRADGQPVARAQPAAAGKKRGRPAGTGKGKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL23</accession>
    <name>W6ZL23_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_87897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">ATCC 44560</strain>
        </source>
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        <property type="entry name" value="Znf_RING"/>
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        </location>
    </feature>
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        <source>
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        </source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLT5</accession>
    <name>W6ZLT5_COCMI</name>
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        <recommendedName>
            <fullName evidence="11">Histidine kinase HHK6p</fullName>
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        <name evidence="9" type="ORF">COCMIDRAFT_21648</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BCTRLSENSOR"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
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    </dbReference>
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        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
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    </dbReference>
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        <property type="entry name" value="HIS_KIN"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="532"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="746"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="1041"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="239"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <end position="1213"/>
        </location>
    </feature>
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        <location>
            <begin position="1237"/>
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        </location>
    </feature>
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        <location>
            <begin position="1301"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="572"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="706"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="267"/>
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        </location>
    </feature>
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            <end position="1190"/>
        </location>
    </feature>
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        <location>
            <begin position="1192"/>
            <end position="1202"/>
        </location>
    </feature>
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        <location>
            <begin position="1241"/>
            <end position="1256"/>
        </location>
    </feature>
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        <location>
            <position position="1096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1363" mass="152585" checksum="5B3074A90360F5F8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLU2</accession>
    <name>W6ZLU2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Muconate cycloisomerase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682295.1">
        <property type="nucleotide sequence ID" value="XM_007684105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLU2"/>
    <dbReference type="GeneID" id="19121038"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_270"/>
    <dbReference type="eggNOG" id="ENOG502S1IZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052062_0_0_1"/>
    <dbReference type="OrthoDB" id="1715191at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF4">
        <property type="entry name" value="CYCLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="40386" checksum="7FD743F72D5061FE" modified="2014-04-16" version="1">MGVHHLLTGSYTNTSLYLLAFDTVAKTLTLNSTVPGFGLHQYVTSNAARDVIYATTMSEPPRIFSWSRTVNNEITHINTANVTTSSCYISDNGNFTFSAGGSGARVNAIDEDGGIGEVVSEMFYVPQQEIPRVDKTRSAVLYGGHGFDVNVNSKGFVPHLAWDAIFMYGILSNGTAKLLSINLSPEFGDGPRNVYPSSDGKWLYVINEHSQYLDIYEVEETNLKHTQRASAIPDQVRGKYTYRSNAVRLSRDGQTIFTSTRGWNNAAANGWVAAFMLDDTGKLASTDALTYYEAPLTLGSAAGLRVAFWEDETNADPTGLTDYMYLSDTQEGYMYILGWTPSTRNLTQVAALHYPDNAAPYEAVWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM17</accession>
    <name>W6ZM17_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_80282</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. Plays a role in both tRNA-processing and mitochondrial metabolism. Involved in the 2-thio-modification of both 5-carboxymethylaminomethyl-2-thiouridine in mitochondrial tRNAs and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) in cytoplasmic tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(sulfur carrier)-H + L-cysteine = (sulfur carrier)-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682394.1">
        <property type="nucleotide sequence ID" value="XM_007684204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM17"/>
    <dbReference type="STRING" id="930090.W6ZM17"/>
    <dbReference type="GeneID" id="19125643"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80282"/>
    <dbReference type="eggNOG" id="KOG1549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_2_1"/>
    <dbReference type="OrthoDB" id="10250117at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990221">
        <property type="term" value="C:L-cysteine desulfurase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070903">
        <property type="term" value="P:mitochondrial tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000003">
        <property type="entry name" value="Cysteine desulfurase IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000002">
        <property type="entry name" value="Cysteine desulfurase IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02006">
        <property type="entry name" value="IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010611">
        <property type="entry name" value="PRK14012.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601">
        <property type="entry name" value="CYSTEINE DESULFURYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="12">
        <location>
            <begin position="105"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC51018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="504" mass="55013" checksum="57A74B9BEAF408F8" modified="2014-04-16" version="1">MPNIAPTIARQALRIASRRYPSPAFARTAGVAARRHYVSESKSSQATVNVDTAIKQEQRAFLDKTGERPSDAAMPTTGMGADAMMSPSAGILKQATVMDQGSRPIYLDMQATTPMDPRVVDKMMPFMTGMYGNPHSRTHAYGWETDTAVEEARANIANLIGADPKEIIFTSGATESNNMSIKGVARFFGRSGKKKHIITAQTEHKCVLDSCRHLQDEGFSVTYLPVGSNGLIDMAQLEAAMRPDTALVSIMTVNNEIGVVQPVEEIGRLCRSKKIFFHTDAAQAVGKIPIDVNKMNVDLMSISGHKIYGPKGIGACYVRRRPRVRLEPIISGGGQERGLRSGTLAPPLAIGMGEAARICKEEMEYDTKRITALSNRLLEGLLSLEHTTLNGDRERHYPGCVNVSFAYVEGESLLMALKDIALSSGSACTSASLEPSYVLRALGSSDESAHSSIRFGIGRFTTDSEIDYVLNAVKERVTFLRELSPLWELVQEGVDLNTIEWSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMK9</accession>
    <name>W6ZMK9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_86558</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gamma-BBH/TMLD family.</text>
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        <property type="protein sequence ID" value="EUC48764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="406634at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045329">
        <property type="term" value="P:carnitine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
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        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF25">
        <property type="entry name" value="OXIDOREDUCTASE AIM17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="8">
        <location>
            <begin position="213"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC48764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="494" mass="56242" checksum="FB0D3DA6D68C7527" modified="2014-04-16" version="1">MTSNIISKLPSRHLRLQVTNACKTRAAVQGRSLRFHSCWRSPNPAEHANRSPATHGPFRPTRPRQQQPQLRQVEWAEEQGNPVQDLSAGAPAESISVNIDGQARVFDAAFLRDSCTCVRCVDQYSNNRLFQTSDIPVDIKGSARSVVDDKKGDSIEVQWDSDVKGFGPEHRTRHSINWLRQAFNTEAQTSSGVRYDDRVFWDGKEITKANKWLDYDAYMSRDETLFEALTHLHRYGLLFISNVPDSEESVVSLASRVGTLKDTFYGRTWDVRSKPKAENIAYTPDYLGLHMDLLYTANPPHLQLLHSLRARTPGGESFFSDAFAAAHQLREQSVDHFNTLCNFPVTYHCHQLPNHYHFTRPVIETFPCPKGTEITSSTIRRINWSPPFQAPVQMPHGSSATPSLRSYVAAAHAYEKLLSSPDNLYEYRLNEGECVIFDNRRVLHARRAFDASKGERWLKGAYVDNDVFFSKLRVLQEVFEGRWFADGVVREAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMN9</accession>
    <name>W6ZMN9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_79504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682247.1">
        <property type="nucleotide sequence ID" value="XM_007684057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMN9"/>
    <dbReference type="STRING" id="930090.W6ZMN9"/>
    <dbReference type="GeneID" id="19125488"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79504"/>
    <dbReference type="eggNOG" id="ENOG502QW3V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010781_1_1_1"/>
    <dbReference type="OrthoDB" id="3561737at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024436">
        <property type="entry name" value="DUF3824"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35487">
        <property type="entry name" value="DUF3824 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35487:SF1">
        <property type="entry name" value="DUF3824 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12868">
        <property type="entry name" value="DUF3824"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3824" evidence="2">
        <location>
            <begin position="345"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3824" evidence="2">
        <location>
            <begin position="589"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="576"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="595"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="684"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="798"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="865"/>
            <end position="877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="892" mass="102262" checksum="239D123334C646BC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP57</accession>
    <name>W6ZP57_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963985">
        <property type="protein sequence ID" value="EUC45391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688086.1">
        <property type="nucleotide sequence ID" value="XM_007689896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZP57"/>
    <dbReference type="GeneID" id="19123127"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36868"/>
    <dbReference type="HOGENOM" id="CLU_2183483_0_0_1"/>
    <dbReference type="OrthoDB" id="3695109at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="109" mass="11233" checksum="61B62375853EA76C" modified="2014-04-16" version="1">MRPSEIAHAHASTCTRSGQLARGSPAQSAVAVVPRSQYGGPGAMTAMAAVSRVLTAATLRVCQPLLPVSNGGGGDSNDTKKPHAERWVGVCVCVCASPVTPTPTYILRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQD0</accession>
    <name>W6ZQD0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_4967</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
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                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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</entry>
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                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="12"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="97"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="193" mass="21829" checksum="6B351B469B4AF460" modified="2014-04-16" version="1">MKYIHSEEELPIPEGVKVSIKNRNVVVEGPRGKLSKSLGHLAVSFTHPKKDLIKIELHHGIRKSVATLRTVRTLINNLIIGVTKGYKYKMRYVYAHFPINVNLEKNSESGCWEVEIRNFIGEKLVRRVVLRPGVDVEASKNVKDQLELSGNSLEDVSQGAADIQQICKVRNKDIRKFLDGLYVSERGNIVEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTK1</accession>
    <name>W6ZTK1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_31772</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682535.1">
        <property type="nucleotide sequence ID" value="XM_007684345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTK1"/>
    <dbReference type="GeneID" id="19121956"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31772"/>
    <dbReference type="eggNOG" id="KOG1237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004790_4_2_1"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000085">
        <property type="entry name" value="MFS peptide transporter Ptr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="548"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="611" mass="67144" checksum="D1288A2F413BBA0E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTY8</accession>
    <name>W6ZTY8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">SMC hinge domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_80739</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682625.1">
        <property type="nucleotide sequence ID" value="XM_007684435.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZTY8"/>
    <dbReference type="GeneID" id="19125721"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80739"/>
    <dbReference type="eggNOG" id="KOG0933">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001042_9_1_1"/>
    <dbReference type="OrthoDB" id="10255539at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03273">
        <property type="entry name" value="ABC_SMC2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000278">
        <property type="entry name" value="Structural maintenance of chromosomes 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000385">
        <property type="entry name" value="Structural maintenance of chromosomes 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027120">
        <property type="entry name" value="Smc2_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="SMC hinge" evidence="14">
        <location>
            <begin position="903"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="771"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="618"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="820"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1065"/>
            <end position="1321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC50994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1560" mass="175262" checksum="860AD08C6CD1B1A0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU62</accession>
    <name>W6ZU62_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_3786</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_3786"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24306">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24306:SF7">
        <property type="entry name" value="AHBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="667" mass="74094" checksum="73D2189A26970203" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUE5</accession>
    <name>W6ZUE5_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_3610</name>
    </gene>
    <organism evidence="4 5">
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502SUC2">
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    <dbReference type="OrthoDB" id="4161589at2759"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-0472">Membrane</keyword>
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    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="104"/>
        </location>
    </feature>
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            <begin position="1"/>
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        </location>
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    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36860" checksum="F2C0FB80DF77460B" modified="2014-04-16" version="1">MPTTSSSTSTPLSPSVRILHSVSEAMSDCHDESRRARKRATDRKSQRNHRERQKAYIQHLEQSLATFKAAADSDQRVSRLVAEIDRLQRKCSSLELQLARVRAVVCDTPNHDVEQVLPQETYTASNLGHDDLGLSDQGGDFTAAGGDLPDMQVGTCDADKSLSADDSNLSVRDLRMYAIDCDPPTRDGDPQAATPLQDIPGIDMVQTATDMITEQLFTMLTPTHDPLASLTDTCPVAFSSPCLPRYTAAAGISDRCLLAMLEEARAEHRQRSFDTTKPSLRRLLCMPACDTLAFRLFHYIKSYGAMPLHILLSIFWVQYLFLRVRYSIQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUM9</accession>
    <name>W6ZUM9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_79877</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682189.1">
        <property type="nucleotide sequence ID" value="XM_007683999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUM9"/>
    <dbReference type="GeneID" id="19125559"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79877"/>
    <dbReference type="eggNOG" id="ENOG502RR6N">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_486712_0_0_1"/>
    <dbReference type="OrthoDB" id="5314997at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC51244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="479" mass="56285" checksum="11B79F74BBD3A924" modified="2014-04-16" version="1">MPEPSQYFNFFGLPREIRDKVYEYTLCSFSQHRGPYDITQCAALCSWTDVQICHFTGNLNLLLANQQTHNEGYKIMLERNQFVIVQIHDSVNECAMIHGHLPPTFVLYSAYHNELEQMRPESYPWHTMRIMLGSKNNLPGEMAMNGEYTEIAMLLEDCMDILKRFALRVTDETLPDPNGRLPPTRLPIKVIVDLNPKRKECDRETSYMHLRKSRSAIDQKKLLKHIGDTFRAYDNFEIKNCDDEALAAEVVQQVSKDPSISLAFFQTHIERHAHSSEASWNQGNIVECANFCTEGLELVHRVRFSAPLVYQLCDEGLQNCLHTSQVIHRLYYLLARCTFAHLSTLMAKRVEKDNYHYIGDTAHALFDLLKTHKKRMHGFLSHYNPPIHEEAEMNFMKAKALRVEWEFHSMAPWGEMLRCIEEAKRLQPDNPIYEEEERKAKIWLEDDARYNAWLRTVDWATHLNMRYWRMEIDKSVFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUY2</accession>
    <name>W6ZUY2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_79444</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682262.1">
        <property type="nucleotide sequence ID" value="XM_007684072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUY2"/>
    <dbReference type="STRING" id="930090.W6ZUY2"/>
    <dbReference type="GeneID" id="19125475"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79444"/>
    <dbReference type="eggNOG" id="KOG0758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_16_0_1"/>
    <dbReference type="OrthoDB" id="14252at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015227">
        <property type="term" value="F:O-acyl-L-carnitine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902603">
        <property type="term" value="P:carnitine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006839">
        <property type="term" value="P:mitochondrial transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000060">
        <property type="entry name" value="Mitochondrial carnitine carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF4">
        <property type="entry name" value="CONGESTED-LIKE TRACHEA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="30"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="128"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="235"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC51394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="34330" checksum="DEB4D513A0D5354B" modified="2014-04-16" version="1">MSGTADTVIEKLPSKAELKEDVKVATKSSLQSLRALIAGGVGGVCAVIVGHPFDLVKVRMQTAEKGVYSGAMDVVRKTIAKEGVARGLYAGVSAPLVGVTPMFAVSFWGYDLGKQLVSSVSKVENNQYSVAQVSAAGFFSAIPMTIITAPFERVKVLLQIQGQKQLAPGEKPKYSGGLDVVRQLYKEGGIRSVYRGSAMTLARDGPGSALYFATYEVVKRNLTPKDPVTGQPGSLSMGAVMVAGGAAGIAMWIPVFPVDTIKSRLQSAEGRPTISGTIKGIHSSGGLKAFFPGIGPAMARAVPANAATFAGVELAQKAMTKMFDRDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1V7</accession>
    <name>W7A1V7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683433.1">
        <property type="nucleotide sequence ID" value="XM_007685243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A1V7"/>
    <dbReference type="STRING" id="930090.W7A1V7"/>
    <dbReference type="GeneID" id="19126174"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83026"/>
    <dbReference type="eggNOG" id="ENOG502RZH4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027223_1_0_1"/>
    <dbReference type="OrthoDB" id="10050400at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031942">
        <property type="term" value="C:i-AAA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24145">
        <property type="entry name" value="Mgr3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:002665">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040201">
        <property type="entry name" value="Mrg3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142:SF1">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="48552" checksum="CFD0E5773CA90284" modified="2014-04-16" version="1">MLSRTIARAAPRVSAYARCEAQAPLERCTRRPATAWRPVQQPLGRRHASMRVQFSEQYRKSPVLFPFAIGVIALVSGICVFYIPWYYKNVIIKPYHNFPEPVAKKLRKALFYSRGKWLDIREANKHFRQALALADELGMDPFSDEIMGVKYTIAQLFEDAGYFSLAIDVLEIMRNDCQRWVDEFSDKHWTTGNRSRVKKNMVQINLKLGQLYDVRYVNEPENGEKRLVEAVESALKEQQRREKEGVKNGEGPWLTNEEMGGTLEALGTHYEQFDSHYLATPLFVKALQLCPPNSCHSVVLMNNISTCLVQQTPPSSSDAITMSPLPSDFPVSNTAPRALLIEQARQWATRALEQARQIKSPDRTEECDMGCAVATHNLGEFFEMEGKTAEARRQYEEAAALAKKMGFAEGVANARAGLKRVKELEKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W7A496</accession>
    <name>W7A496_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable endonuclease LCL3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Probable endonuclease lcl3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_80503</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LCL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682586.1">
        <property type="nucleotide sequence ID" value="XM_007684396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A496"/>
    <dbReference type="GeneID" id="19125682"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80503"/>
    <dbReference type="eggNOG" id="ENOG502RZZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046484_0_1_1"/>
    <dbReference type="OrthoDB" id="430293at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000029">
        <property type="entry name" value="Probable endonuclease lcl3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="TNase-like" evidence="16">
        <location>
            <begin position="78"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="225"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC50911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="273" mass="30988" checksum="27D67ED51E447A2C" modified="2014-04-16" version="1">MRWPWSGNDDDGEKKSGLSSWTAPTKSGGFAGSWTEPQTLIPSLALTASLVAALRFYKAYLRRIPTVNHIKPDYFRRRSLFGQVTSVGDADNFRFYHTPGGRIAGWGWLPWKRVPTTKETLAQQTLHIRIAGVDAPELAHWGREAQPFAKEAQDWLIGLILHRRVRAYIYRRDQYDRVVAQVYVRRWFFKKDVGLEMLKAGLATIYEAKSGAEFGTAEDQYRAAEKKAREDQVGMWAKPSPRQRLGGVPKKALESPREYKARHAAADKAKKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4E8</accession>
    <name>W7A4E8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">Amino-acid acetyltransferase, mitochondrial</fullName>
            <ecNumber evidence="5 15">2.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 15">Glutamate N-acetyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13 15">N-acetylglutamate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_80628</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">N-acetylglutamate synthase involved in arginine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the acetyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.1" evidence="5 15"/>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC51001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682631.1">
        <property type="nucleotide sequence ID" value="XM_007684441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A4E8"/>
    <dbReference type="STRING" id="930090.W7A4E8"/>
    <dbReference type="GeneID" id="19125702"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80628"/>
    <dbReference type="eggNOG" id="KOG2436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013088_0_0_1"/>
    <dbReference type="OrthoDB" id="5585968at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006592">
        <property type="term" value="P:ornithine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000049">
        <property type="entry name" value="Amino-acid acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011190">
        <property type="entry name" value="GlcNAc_Synth_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006855">
        <property type="entry name" value="Vertebrate-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342:SF4">
        <property type="entry name" value="AMINO-ACID ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04768">
        <property type="entry name" value="NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007892">
        <property type="entry name" value="NAGS_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51731">
        <property type="entry name" value="GNAT_NAGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="17">
        <location>
            <begin position="521"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="450"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR007892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC51001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="720" mass="79796" checksum="27A5C28A83386B76" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A556</accession>
    <name>W7A556_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_31381</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682122.1">
        <property type="nucleotide sequence ID" value="XM_007683932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A556"/>
    <dbReference type="STRING" id="930090.W7A556"/>
    <dbReference type="GeneID" id="19121855"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31381"/>
    <dbReference type="eggNOG" id="KOG1257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011405_5_2_1"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10380:FF:000007">
        <property type="entry name" value="Malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="10">
        <location>
            <begin position="73"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="9">
        <location>
            <begin position="260"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC51236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="581" mass="64827" checksum="1E4EACD6E192310C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YL91</accession>
    <name>W6YL91_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_41622</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964215">
        <property type="protein sequence ID" value="EUC39967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693513.1">
        <property type="nucleotide sequence ID" value="XM_007695323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YL91"/>
    <dbReference type="STRING" id="930090.W6YL91"/>
    <dbReference type="GeneID" id="19124102"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41622"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_4_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="98"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="347" mass="39164" checksum="C1248C33E4CC7277" modified="2014-04-16" version="1">MTVKIPSVADHQLSKGYQTPEEWLVRLDPEWVRIWNAYGGHHRQAEEVPIEKVRRKPLAYSFTYPTWSEFDIPVSRPAGHIKVRVYTPEGQGTFPVHVNYHGGGWILGGLNSEAAWCRSVCNNTGIVIVDVDYRLAPEFVFPTAIYDSWDALQWVLSHAEDLNIDATSVSIGGLSAGGHMSAVLSHMARDAGLELKLALLVVPSTDFRWLIAEQPLRSVIAKRYPSTAQYKDAPWGGLKREQWFLNYWIPTDIRRAACDDWMASPILAQSFERLPPTHIITAEFDICRDEAHQYGELLADSGNLVTQKCYRGMPHAFGHYIHPKKGLSKGHEYVHDTSKLLQQAHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLC8</accession>
    <name>W6YLC8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">geranylgeranyl diphosphate synthase</fullName>
            <ecNumber evidence="1">2.5.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_109894</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.29" evidence="1"/>
    <dbReference type="EMBL" id="KI964209">
        <property type="protein sequence ID" value="EUC40012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693470.1">
        <property type="nucleotide sequence ID" value="XM_007695280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLC8"/>
    <dbReference type="STRING" id="930090.W6YLC8"/>
    <dbReference type="GeneID" id="19119514"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109894"/>
    <dbReference type="eggNOG" id="KOG0777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_10_0_1"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046165">
        <property type="term" value="P:alcohol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF72">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G01210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="330"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="702" mass="79274" checksum="A26EB13964F1D669" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQE9</accession>
    <name>W6YQE9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964270">
        <property type="protein sequence ID" value="EUC39718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693763.1">
        <property type="nucleotide sequence ID" value="XM_007695573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQE9"/>
    <dbReference type="STRING" id="930090.W6YQE9"/>
    <dbReference type="GeneID" id="19119659"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110756"/>
    <dbReference type="HOGENOM" id="CLU_213569_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="53" mass="6570" checksum="1C5EB04D7564D9F9" modified="2014-04-16" version="1" fragment="single">YKAITVLVLKYRIFQKFILNFNKLFIPKYYNIFLVNLDIKKKLLISFYLEIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR64</accession>
    <name>W6YR64_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">3-hydroxyphenylacetate 6-hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_41589</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Aromatic compound metabolism; phenylacetate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964210">
        <property type="protein sequence ID" value="EUC40003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR64"/>
    <dbReference type="GeneID" id="19124091"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41589"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_4_1"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000072">
        <property type="entry name" value="3-hydroxyphenylacetate 6 hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF9">
        <property type="entry name" value="P450, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00060591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="59442" checksum="2746F86614869D64" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRE2</accession>
    <name>W6YRE2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_109683</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964200">
        <property type="protein sequence ID" value="EUC40083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693400.1">
        <property type="nucleotide sequence ID" value="XM_007695210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRE2"/>
    <dbReference type="GeneID" id="19119483"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109683"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_27_3_1"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF23">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="456"/>
        </location>
    </feature>
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        <location>
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            <end position="498"/>
        </location>
    </feature>
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        <location>
            <begin position="38"/>
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        </location>
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        </location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="540"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="551" mass="59362" checksum="8641A068718DDBD1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRU5</accession>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="432" mass="47008" checksum="F8A0DA537C7F841D" modified="2014-04-16" version="1">MSSFNYDRYDRRQSSSRNRSALGFYVPLILTVTVATAGLAAWVWSAREDGQDYSSDDDLSYGEDSAHDRRNGRAPMGRDLGPGGVGGEAYSNDATLLGRAQGVIRRTPSPQQFFDTVSKKTAAGWAAAGAAAGAALASIREEDKDEAFGDHSRWSEEAALRRNVEAQSRDSAAAVDAQTKSFAASMRKIEDKNWGKRKTVVLVVSAESFSENHFDDSATYREETATILSHLPDTDFSRINLFVLVYSPTFRSRPQSRANSSLGGSYSAISTPARTPGEELSSIDPIVYTPAPSTRDSDTALWNTLHSQALRLVEDPAMVMPFSTTTGFVHMLRHISPDLVYVVDALSGVNGQNIEDVRKWVGQTIVVVGGDGTGLGGLVDTDDEGPLRKGKENEHTVRWWQVTDMVGLGKGVEVVDASRLADDYERRVGGRE</sequence>
</entry>
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    <name>W6YRX6_COCMI</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">COCMIDRAFT_108985</name>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="154" mass="17750" checksum="ABD1D3FE3CE13644" modified="2014-04-16" version="1">MNSAIRKVPRGRPLEANNFDHIVRCYGGQTIAIEMEPHHMQKSKQPRDLIQYIDFLNRRNGELRLELTFYRECHRHAEKFKEKIEGISQDLLQACIIGLLDGIDFGEIRDLSNTASDAIDQFSHDQEQAFNAFIAPYKASKSPKKSTISMEGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS37</accession>
    <name>W6YS37_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_108796</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC40445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694849.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19119312"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108796"/>
    <dbReference type="eggNOG" id="ENOG502S15T">
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    </dbReference>
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    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF11">
        <property type="entry name" value="ESTERASE_LIPASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="6"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="250" mass="27396" checksum="38A7A7A8122329AB" modified="2014-04-16" version="1">MSTPTIVFVPGAWHTPGCFDVTREQLHQRGWETEAVAHPSVGAEPPKKGLADDAVALRSTLEGLADDGKDIVLVVHSYGGLVGQNALEGLGYNQRQAVGKKGGVIILVYLAAFVASKGATVQAMLGGQFLPWIQFDGDYCYATTPEIVFYHDVDDGPRRSAIERLKRQSARIFTDEVTYEPWHEILSMYFFCENDKALPLPIQQQMAQTLGQDAPTFKSVGSHSPFLSQPQEVIEGLEYAAQLGQSNKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSQ0</accession>
    <name>W6YSQ0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964156">
        <property type="protein sequence ID" value="EUC40553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692938.1">
        <property type="nucleotide sequence ID" value="XM_007694748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSQ0"/>
    <dbReference type="GeneID" id="19119266"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108531"/>
    <dbReference type="HOGENOM" id="CLU_3049991_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="54" mass="5476" checksum="FEAAD66ABEE01174" modified="2014-04-16" version="1">MTRAKLGCKVIREATQIRASPASPAPPTSTASLPPTALPLSTSKVLPVGPPSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTA1</accession>
    <name>W6YTA1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_107939</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964141">
        <property type="protein sequence ID" value="EUC40753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692721.1">
        <property type="nucleotide sequence ID" value="XM_007694531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTA1"/>
    <dbReference type="GeneID" id="19119152"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107939"/>
    <dbReference type="eggNOG" id="ENOG502S8Q4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_689249_0_0_1"/>
    <dbReference type="OrthoDB" id="3695711at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="345" mass="37900" checksum="2F420884493C42B8" modified="2014-04-16" version="1" fragment="single">MQLKNLTIEVPLSATQHGSSRIFCVRGPPWRDTLLVITFFATSYIAHAATVKSTPGEGTVSIAFNTFMALCFPMFGLLRALNAIARGARFGGSELKNACRAGALCMVVRNPEWRPSPGDTLAAVLEQRSQSDEESNVTSDIIDAKMVNYFPTYAREDSSAWAYFDTIGSRAYVDPDLIRIHGTYFLSEGYSFAIVPRNACLSEIDRIDSRPLEPQNGSTPDVNSDISSSYSVAKAIASLIQILGALSIILLRKPDTIERWGYASFQLTVVPYLVMTVVNFTSNALTADYACLYMVESAVMREARNRGSRFKGTVAALEEYTGPLSPDVSTKDISVWTGLTQKHIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTA5</accession>
    <name>W6YTA5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_30344</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964141">
        <property type="protein sequence ID" value="EUC40758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692717.1">
        <property type="nucleotide sequence ID" value="XM_007694527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTA5"/>
    <dbReference type="STRING" id="930090.W6YTA5"/>
    <dbReference type="GeneID" id="19121661"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30344"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005720">
        <property type="entry name" value="PRK07538.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF268">
        <property type="entry name" value="5-METHYLPHENAZINE-1-CARBOXYLATE 1-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="11"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="451" mass="49684" checksum="05086902A219BF7B" modified="2014-04-16" version="1">MPFLHSGTQPKILIAGAGIGGLTTALALHSAGFNNIQIFEASSTLTTLGVGINVQPSAVLILRNLGLLEALEKTGIKTQELNFYNRHGDSILSEPRGRNAGYMVPQFSIHRGEFQMLLLSAVKERLGEDVLHLNHAFTAFDQNDNSITARFSRRRDGEPAEMSSVTGDVLIAADGINSTARKILYPNEGPPRFSGRMLWRGCIERDQYLTGASMVWAGHADQKFIAYPISQRSADKGKSMVNWIAELRIRAKDDVDLTPPKTDWTKAVKKDVFAGPFESWRCGGLEMKDLIDNTEKVFEFPMSDRDPVEAWSFGRLTLLGDAAHAMYPIGSNGASQAIIDAETLAKHLSSNTSDVQGALKAYELERLPPTSKIVMANRANGPDHVLQLAEERAPDGFKNVYDVIPKDELEEIGRVYKKVAGFEMESVNEKARETEGVDVQKGLKSPQDWIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTK1</accession>
    <name>W6YTK1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_107671</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="KI964134">
        <property type="protein sequence ID" value="EUC40868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692617.1">
        <property type="nucleotide sequence ID" value="XM_007694427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTK1"/>
    <dbReference type="STRING" id="930090.W6YTK1"/>
    <dbReference type="GeneID" id="19119093"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107671"/>
    <dbReference type="eggNOG" id="KOG0417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_13_2_1"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031371">
        <property type="term" value="C:ubiquitin conjugating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006301">
        <property type="term" value="P:DNA damage tolerance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010994">
        <property type="term" value="P:free ubiquitin chain polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044395">
        <property type="term" value="P:protein targeting to vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23813">
        <property type="entry name" value="UBCc_UBE2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000020">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="149" mass="16893" checksum="EBA55A8417604B3A" modified="2014-04-16" version="1">MALPKRIIKETERLVNEPVQGISATPHDDNLRYFDVTIDGPSQSPYEGGVFKLELFLPDDYPMTPPKVRFLTKIYHPNIDRLGRICLDVLKSNWSPALQIRTILLSIQALLGAPNPDDPLANDVAQAWKENKNQAIQTAQEWTQQYAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUI9</accession>
    <name>W6YUI9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_101734</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690381.1">
        <property type="nucleotide sequence ID" value="XM_007692191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUI9"/>
    <dbReference type="GeneID" id="19117921"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101734"/>
    <dbReference type="HOGENOM" id="CLU_2549048_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="83" mass="8977" checksum="1D4B8CEABE7274D6" modified="2014-04-16" version="1" fragment="single">PYFCYPISQLTSLAAWSLVPHSKLPLSSLAFLPSRPSPVSLYPPPEQTNNTSPFLAAGPQIQAIPRYAIHPALPLIPPPSSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVV2</accession>
    <name>W6YVV2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_45017</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964292">
        <property type="protein sequence ID" value="EUC39649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693837.1">
        <property type="nucleotide sequence ID" value="XM_007695647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVV2"/>
    <dbReference type="GeneID" id="19124262"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_45017"/>
    <dbReference type="HOGENOM" id="CLU_2503816_0_0_1"/>
    <dbReference type="OrthoDB" id="5271495at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="70" mass="7751" checksum="4BFDB85890B715D7" modified="2014-04-16" version="1" fragment="single">MGTEKTRTTAPIGTCEGRVLLGYIEPTKYNQVVDIILKESAPRNNKDRCQDWTLDCVIALEAEELLPAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVX3</accession>
    <name>W6YVX3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_27965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964025">
        <property type="protein sequence ID" value="EUC43567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689902.1">
        <property type="nucleotide sequence ID" value="XM_007691712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVX3"/>
    <dbReference type="GeneID" id="19121217"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27965"/>
    <dbReference type="HOGENOM" id="CLU_112522_0_0_1"/>
    <dbReference type="OrthoDB" id="3693951at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886313" evidence="1">
        <location>
            <begin position="19"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="176" mass="18850" checksum="04A8FF0515DB1F6A" modified="2014-04-16" version="1">MRTSASFATFLLCGIATAQFGADTLLGSMSGMTCSNGESTLPPSSHNNLLGSCSRNSWKPVVVKRQAHSGADSDLVNVSLEAPEDGVLVISDSHGRCEHFEVYIDDQLIGETSGTGALDFSACGLPDECMEKNGGQHGYFALPKGNYKLGLKWTKVTPQCDRSSIGEGHYKFHRKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW17</accession>
    <name>W6YW17_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_29550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964089">
        <property type="protein sequence ID" value="EUC41733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691753.1">
        <property type="nucleotide sequence ID" value="XM_007693563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW17"/>
    <dbReference type="GeneID" id="19121527"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29550"/>
    <dbReference type="eggNOG" id="ENOG502RZ90">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_912422_0_0_1"/>
    <dbReference type="OrthoDB" id="2150942at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="34497" checksum="9D636135E4A61DEA" modified="2014-04-16" version="1">MASETDEASKIDSGKFYNEYKGHPIADLTIFRNITLTEHPDKPIIYLAGDSSLDNKFWLKERISSSSQIPAIYHYTLATPITLIPDVAYWLNSALSTRATCINTAVEESLLRSRDTDLLPHDAFIRSSIRANDILVVSVGSNDIALNPSVETSAHMFQLAWLTPRKSIEDGSAWGLPYFRNLFGTKIQEYIARLTEVTKPRTVVVCMIYFPLESGKGQSGWADGKLRVLGYERDPGQLQAAIRELYKSATEEIKVEGVQVVPCALFEVLDGKGAGDYVERVEPSGEGGRKMAGEFVRVLEGVLGEGVGMENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWF3</accession>
    <name>W6YWF3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_8480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964083">
        <property type="protein sequence ID" value="EUC41853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691615.1">
        <property type="nucleotide sequence ID" value="XM_007693425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWF3"/>
    <dbReference type="GeneID" id="19126536"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8480"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_1_1"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF28">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889462" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="57"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="494" mass="53560" checksum="C86DBB93D1EB74DB" modified="2014-04-16" version="1">MRFLAVSSISLLASTAAAYSSSCNACEELSSVLPNNTFYPSAQTYNASIQSYPFLQLRLHPSCIVRPSTSKDVSTAVSILAQTNCTKFAIKGGGHNANAGSNNIDDGVTIDMQSLKKVEVAKGDQVVQVGAGALWQDVYDTAEKRNRTVMGGRIGVVGTAGFLTGGGISFLSPEHGWACDAVENFEVALADGKLVNANSTSNSDLYAALKGGQNNFGIVTRFDLKTYPARPIWGGRTVYGPNATQALLSAYTDFKSGEYDPYAAGWVTVRYNHTAGTFNPVSIMWYTKPEQKPGALKAIIDVQPQVMNGRVEAPISEHTRNASRQVSANPQRTIWATTSFKISPTIMHSIHDMWSKIVPEISEQYASGKPIAEITFQALPAPPRNGTAPNVLGFGPEETPEKDLVFLQIIFTFEDAAAADGFEEGLIDLVKLVEDITKKEGVYHPYKYLNFAASFQDPLGSYGKKELRKMYKVADKYDPQGVFQTLVPGGFKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWH8</accession>
    <name>W6YWH8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_27850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964021">
        <property type="protein sequence ID" value="EUC43722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689760.1">
        <property type="nucleotide sequence ID" value="XM_007691570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWH8"/>
    <dbReference type="GeneID" id="19121195"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27850"/>
    <dbReference type="HOGENOM" id="CLU_1539754_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="174" mass="19991" checksum="7CC280850B8AFC14" modified="2014-04-16" version="1">MVKRVWAQVDVAAFLERFTTGCHFGQTDLFRFGLLLRSLTHSSPFWSQYFPTTTTGCPSGEEPSWRCQKIELGGGTPSGGDGDDDNDEEENEEEEVGRLLQESDDDENEEEDEEEVGRLLQEQDEEDEEEEEEEEEEKEDLFRQDLADGSASLHRLLPEDAIVMVVWHGKRIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWX6</accession>
    <name>W6YWX6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_104591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964076">
        <property type="protein sequence ID" value="EUC42023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691465.1">
        <property type="nucleotide sequence ID" value="XM_007693275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWX6"/>
    <dbReference type="GeneID" id="19118541"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104591"/>
    <dbReference type="eggNOG" id="ENOG502SV22">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1454104_0_0_1"/>
    <dbReference type="OrthoDB" id="5408598at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889308" description="Secreted protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="18635" checksum="1F29D4DC1D245CC8" modified="2014-04-16" version="1">MFASGWKKTLSVAAVVLALSSGQVLAACTDGPGWTPEEFAEYQSLNDTTGWAGMEKLAQCTIDADELTPAAPHGRFEARAGGREWQGYSSNGCSGAKTAVTSGFGCGVCVSASNFYFYSGWLWRERAANPYPTADYYTQSGCRGTKLHHQGIEGSQTTSCNNVNRAASVILYQGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXJ5</accession>
    <name>W6YXJ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_8128</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964067">
        <property type="protein sequence ID" value="EUC42270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691200.1">
        <property type="nucleotide sequence ID" value="XM_007693010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXJ5"/>
    <dbReference type="STRING" id="930090.W6YXJ5"/>
    <dbReference type="GeneID" id="19125840"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8128"/>
    <dbReference type="eggNOG" id="KOG4730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_9_0_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="37"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="487" mass="55058" checksum="83A2D4FBFA831A04" modified="2014-04-16" version="1">MALYTYDTRPSFSADVLVRGTPEYDRCRRNNPSATTPDRYPREIHVVKSPKQVSAALKRATELGVTVGIRGSGHAFPLSALIQDGILIDTSSLNRYVDYDPDSREISFGPAVRVEEVAAKLKEVKRFFPHGHAPTVGAAGFLLAGGQGWFVRGWGATCQEWITQMEIVVPDGRVVIASPTENTDLFWAARGSGLGFFGVVTKFWARTIPSSQLWERTFTFQLRDKYETLMTWFFEKAEETPKYGTDLNLTIFYPEKYDTSILTDDIPKTSQLHLGLSLLCYSDTEREARTLLSAYDDVPESVKDCLVDMRPVSKREFADIFDKKREFIGNKYGENWQILSLLSEPTVPIPRLIEAFKPALTELETRITSVFICICDIVANEKVASLSIPQKYYISTVTGWLDQKKGPAIKQRMLDRYKRALPVACGTYPADYDPNVEDANSKPMSDTALAKFLQIRAKWDPNDMFPNYKSFIKTNEKINKLLNKPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY20</accession>
    <name>W6YY20_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_103379</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; D-xylose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964060">
        <property type="protein sequence ID" value="EUC42468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691018.1">
        <property type="nucleotide sequence ID" value="XM_007692828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY20"/>
    <dbReference type="STRING" id="930090.W6YY20"/>
    <dbReference type="GeneID" id="19118285"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103379"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_0_1"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="UniPathway" id="UPA00810"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032866">
        <property type="term" value="F:D-xylose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042843">
        <property type="term" value="P:D-xylose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd19115">
        <property type="entry name" value="AKR_AKR2D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000007">
        <property type="entry name" value="NAD(P)H-dependent D-xylose reductase xyl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044487">
        <property type="entry name" value="AKR2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="9">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC42468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="323" mass="36315" checksum="6F3EE867DA4F0202" modified="2014-04-16" version="1">MASNVPFVTLNDGNKMPQVGFGLWKVDNATCADTVYNAIKAGYRLFDGACDYGNEVECGQGVARAIKEGLVKREDLFIVSKLWQTFHDREQVEPIVRKQLADWGVDYFDLYLIHFPVALKYVDPKVRYPPGWYYDGESKIEHSNASLQSTWEAFEDIKSKGLAKSIGVSNYSGALLLDLFTYAKVKPATLQIEHHPYYVQPHLIELARQHDIKVTAYSSFGPQSFLECDMKVAADTPLLFDHPVIKKIAEAHGKTPAQVLLRWSTQRGLSVIPKSNSPNRLAQNLDVTSFDLKDSEIEEISGLDKNLKFNAPTNYGIPCYVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYD2</accession>
    <name>W6YYD2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AIM41</name>
        <name evidence="2" type="ORF">COCMIDRAFT_27324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM41 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964006">
        <property type="protein sequence ID" value="EUC44352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689129.1">
        <property type="nucleotide sequence ID" value="XM_007690939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYD2"/>
    <dbReference type="GeneID" id="19121105"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27324"/>
    <dbReference type="eggNOG" id="ENOG502SDB7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079430_0_1_1"/>
    <dbReference type="OrthoDB" id="538640at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="entry name" value="Uncharacterised protein YqeY/AIM41 PF09424, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="182" mass="20120" checksum="9A931170931108F8" modified="2014-04-16" version="1">MSLFRATLLQRQLFAPTRITCIRYASTSTPENTVLPRLHTDLKIAMRSKNKPALNTIRGLQAEIINASKTAKPITTDGALYSLIQKQIKASSASIEEFRNAKREDLVEKEQQNLDILKAYAEEIPTVSESEVDSLVKSVVEGLEEGKRNFGSVMGKVMGAVKGRPLDVEYVTKKIQEAVGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYT6</accession>
    <name>W6YYT6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_102780</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="KI964051">
        <property type="protein sequence ID" value="EUC42725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690761.1">
        <property type="nucleotide sequence ID" value="XM_007692571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYT6"/>
    <dbReference type="STRING" id="930090.W6YYT6"/>
    <dbReference type="GeneID" id="19118156"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102780"/>
    <dbReference type="eggNOG" id="ENOG502QTKT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011476_0_0_1"/>
    <dbReference type="OrthoDB" id="68336at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000151">
        <property type="entry name" value="Glucan endo-1,3-beta-glucosidase btgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="131"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC42725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="615" mass="66653" checksum="C6F5453F3A0923B0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZH1</accession>
    <name>W6YZH1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964042">
        <property type="protein sequence ID" value="EUC43005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690462.1">
        <property type="nucleotide sequence ID" value="XM_007692272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZH1"/>
    <dbReference type="GeneID" id="19123589"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38978"/>
    <dbReference type="eggNOG" id="ENOG502S85Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067863_0_0_1"/>
    <dbReference type="OrthoDB" id="1859733at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF1">
        <property type="entry name" value="CONSERVED FUNGAL PROTEIN (AFU_ORTHOLOGUE AFUA_1G14230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886275" description="Malate dehydrogenase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="25649" checksum="F199BD62E6E3C5A1" modified="2014-04-16" version="1">MLFSAIAAAFFYATSAYAVALPPAPGKPHNYTPAKNLDNLAKLFPQSDLTSPDGMALKYVVLGIGTQNYTCANASAVPGTTGAVATLYDIGTKLNNDRDAKWKIATISPLALSMAEWAPQLVDMSLQAQGFQNVAGHHFFADVAGTNTPTFAFDQLSTPYPLCQVAKLGAVDAPKTACSGKNGLPAIQWLYLQHKAGIAQGGITTVYRVETAGGNKPATCQGMPPAWEVKYAAQYWVYGPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZI1</accession>
    <name>W6YZI1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_97433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688746.1">
        <property type="nucleotide sequence ID" value="XM_007690556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZI1"/>
    <dbReference type="GeneID" id="19129062"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97433"/>
    <dbReference type="eggNOG" id="ENOG502SURR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_754680_0_0_1"/>
    <dbReference type="OrthoDB" id="5427732at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886277" evidence="2">
        <location>
            <begin position="21"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="344" mass="35533" checksum="915E1783B54C9049" modified="2014-04-16" version="1">MRSFCQVAVMALPLFSAIAAAEPKDVADHPKTIYATAQEAFQDLLNALPEESLHAALSNLKDFKNGIFESHHRGVENIHSNNPALASKLIVDAVNDLRKRQTPSNGTNSATTASNPPESIQNSTPVPTPSDNLQPETSSAAPPPPSGTSEASADTTRQQTTTAVSTTTQERPAIIPVESTVTKDGKTIVQTTEVLSEVTASVAVTVVRTNTAGSTVTETENRPAVIKTTTDRAGRTTVTTSAVNFAPTAGQVTSTTDSRGSVVLTTLTPGGGLVSSIKLITTTDAQGRQSTMTTYAFVDPVQATGAANSPNAPGNDKPSLQTGAAVANGAQYAAVGLGALAFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZL1</accession>
    <name>W6YZL1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Nuclear thiol peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_101895</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="3"/>
    <dbReference type="EMBL" id="KI964041">
        <property type="protein sequence ID" value="EUC43050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690438.1">
        <property type="nucleotide sequence ID" value="XM_007692248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZL1"/>
    <dbReference type="STRING" id="930090.W6YZL1"/>
    <dbReference type="GeneID" id="19117962"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101895"/>
    <dbReference type="eggNOG" id="KOG0855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_2_0_1"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000157">
        <property type="entry name" value="DOT5p Nuclear thiol peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF23">
        <property type="entry name" value="PEROXIREDOXIN DOT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="15">
        <location>
            <begin position="71"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="228"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00077538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC43050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="261" mass="26971" checksum="FB65B8440C78C0FF" modified="2014-04-16" version="1">MPVELRKRKAAAPVPAPPAKKKAPAKAKKADSEKTVVDKVQDAVVEKVEAVKEAVVSKTNGASTAKSSGAPKVGDTVDLASFGGEIETNDGTKTSLAKLVEESKAGVVLFTYPKASTPGCTTQVCLFRDSYTPLTATGLSIYGLSSDSPKANTTFKTKQKLPYSLLCDPAQTLISAIGFKKAPKGTTRGVFVVDKQGKVLAAEPGGPAATVEVVKKLVGDAEKVPAKEEVEAKEKEEDKKVADTAGEVADSAAKVDAPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZX2</accession>
    <name>W6YZX2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_97082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688608.1">
        <property type="nucleotide sequence ID" value="XM_007690418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZX2"/>
    <dbReference type="GeneID" id="19128983"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97082"/>
    <dbReference type="eggNOG" id="ENOG502SR2P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_468491_0_0_1"/>
    <dbReference type="OrthoDB" id="5430532at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="582" mass="64115" checksum="C9091840AE846D8C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0Z9</accession>
    <name>W6Z0Z9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutaminase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_8945</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964108">
        <property type="protein sequence ID" value="EUC41344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0Z9"/>
    <dbReference type="STRING" id="930090.W6Z0Z9"/>
    <dbReference type="GeneID" id="19127481"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8945"/>
    <dbReference type="eggNOG" id="ENOG502QPQS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008020_1_0_1"/>
    <dbReference type="OrthoDB" id="431715at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032514">
        <property type="entry name" value="GtaA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033433">
        <property type="entry name" value="GtaA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF12">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF5127"/>
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    </dbReference>
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        <property type="entry name" value="GtaA_6_Hairpin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889595" description="Glutaminase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A N-terminal" evidence="4">
        <location>
            <begin position="122"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A central" evidence="3">
        <location>
            <begin position="357"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A central" evidence="3">
        <location>
            <begin position="536"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A central" evidence="3">
        <location>
            <begin position="697"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="808" mass="90334" checksum="4405BF4E7627F8A5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1I6</accession>
    <name>W6Z1I6_COCMI</name>
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        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_99865</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964019">
        <property type="protein sequence ID" value="EUC43805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1I6"/>
    <dbReference type="STRING" id="930090.W6Z1I6"/>
    <dbReference type="GeneID" id="19129554"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99865"/>
    <dbReference type="eggNOG" id="ENOG502RYJ6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033570_0_0_1"/>
    <dbReference type="OrthoDB" id="4657524at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054508">
        <property type="entry name" value="PIR1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018620">
        <property type="entry name" value="Ubiquitin3-bd_protein_But2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39613">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39613:SF1">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09792">
        <property type="entry name" value="But2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22799">
        <property type="entry name" value="PIR1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887058" evidence="2">
        <location>
            <begin position="17"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall mannoprotein PIR1-like C-terminal" evidence="4">
        <location>
            <begin position="62"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin 3 binding protein But2 C-terminal" evidence="3">
        <location>
            <begin position="186"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC43805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="336" mass="35232" checksum="72C4A4BA2CF40555" modified="2014-04-16" version="1">MRYAFVPLALGLGANALVARSDTQCYTLKASGGAQGILGQLGDGQNRIGDNLPTGCYCLCDGGFTDSNGRGCILTPPTTQFQCDVGASPTYGFAVGSDGSVTYNGSGTFYACPVNDNGVYNVYSQPVAGQSKCVKISLAAAGSCGASTTPPPSKPSPSPSPSPTPQPSYPYTPPNACPLDLKGAYQYPHLIVPINADHPDQAYGTQYNATIDSRTCTIFNFDIPPSYAGKTCSAIFLFPKKSDLQTSDYTISGSGHVTVSPLAGPASQGTTWNNQPKKDGDSTSFDLSPGSAWYVETDECEAGATIAYEMCAEGNFALEYFQDYNPSPIGLYVRQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1K5</accession>
    <name>W6Z1K5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylosuccinate lyase</fullName>
            <ecNumber evidence="6">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_99757</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = fumarate + AMP</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="6"/>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689655.1">
        <property type="nucleotide sequence ID" value="XM_007691465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1K5"/>
    <dbReference type="STRING" id="930090.W6Z1K5"/>
    <dbReference type="GeneID" id="19129528"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99757"/>
    <dbReference type="eggNOG" id="KOG2700">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030949_1_1_1"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03302">
        <property type="entry name" value="Adenylsuccinate_lyase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.60:FF:000001">
        <property type="entry name" value="Adenylosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000005">
        <property type="entry name" value="Adenylosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172:SF1">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenylosuccinate lyase C-terminal" evidence="12">
        <location>
            <begin position="373"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC43830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="481" mass="53995" checksum="C4A3F657C4DF9FB2" modified="2014-04-16" version="1">MASGTYTTPLTGRWSSSEMSHLFSKENRHSTWRKLWLYLAESEKELGVEGITDEALTQMREHLTLTDNDFAVAAAEEKLRRHDVMAHVHAFGQVAPAAAGIIHYGATSCYVTDNAELLLMRDALDLLIPKLAKVISNLRSFALKWKSEPALAYTHLQPAQLITVGKRAAHWAQDLLFDLEDLERVRERLLLRGAQGTTGTQASFLEIFKGDGDKCDQLNELLCKKTGFPSCYPVSSQTYTRKVDLIVANAVCGLGSSAKKITGDIRNLASYKELEEPFESTQIGSSAMAYKRNPMRSERVASLSRALLGKHAAFAQTHADQGFERTLDDSAVRRMDIPEMFLLADAILLSLDNVTSGLVVYPKRIDARIQAELPFMITESIIMRLVAKGASRQDAHEEIRVLSHEAGYQVKNEGQANDLVERIRKTEFFKPIWGELDEMMDSKLYIGRSERIVEKVCADLEKHLAKYKNYIENTKTSELHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1S9</accession>
    <name>W6Z1S9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">COCMIDRAFT_6704</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Vacuole membrane</location>
            <topology evidence="15">Peripheral membrane protein</topology>
            <orientation evidence="15">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689547.1">
        <property type="nucleotide sequence ID" value="XM_007691357.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z1S9"/>
    <dbReference type="GeneID" id="19125048"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6704"/>
    <dbReference type="eggNOG" id="KOG0891">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000178_7_1_1"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010972">
        <property type="term" value="P:negative regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016242">
        <property type="term" value="P:negative regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901992">
        <property type="term" value="P:positive regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031137">
        <property type="term" value="P:regulation of conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905356">
        <property type="term" value="P:regulation of snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05169">
        <property type="entry name" value="PIKKc_TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000020">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.150:FF:000001">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000371">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000446">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000487">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000582">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000004">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026683">
        <property type="entry name" value="TOR_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0469">Meiosis</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0926">Vacuole</keyword>
    <feature type="repeat" description="HEAT" evidence="18">
        <location>
            <begin position="704"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="FAT" evidence="21">
        <location>
            <begin position="1243"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="20">
        <location>
            <begin position="2022"/>
            <end position="2340"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="22">
        <location>
            <begin position="2383"/>
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        </location>
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        </location>
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            <end position="2334"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
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            <dbReference type="PROSITE" id="PS50290"/>
        </source>
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        </source>
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        <source>
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        <source>
            <dbReference type="EMBL" id="EUC43925.1"/>
        </source>
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        <source>
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        </source>
    </evidence>
    <sequence length="2415" mass="273312" checksum="B03D295684948F77" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6Z1W7</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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        <name evidence="3" type="ORF">COCMIDRAFT_6677</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </evidence>
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        </source>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
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            <taxon>Dothideomycetes</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
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            <end position="365"/>
        </location>
    </feature>
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        </source>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="66" mass="6935" checksum="B861BB5ADE9B4587" modified="2014-04-16" version="1">MRFSIVVATFFASVALAMPDPLPQGYNGPCARDNCGVNGLNCGNRLCVGWPNTDPALRKGCTCTTA</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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        <source>
            <dbReference type="EMBL" id="EUC44645.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="evidence" value="ECO:0007669"/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
            <begin position="1"/>
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        </location>
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    <feature type="chain" id="PRO_5004889711" evidence="1">
        <location>
            <begin position="19"/>
            <end position="134"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="134" mass="14718" checksum="20A50A100ED1730E" modified="2014-04-16" version="1">MHFLTFLLVTLLAAMAMASPAPIPMPERFEPPWPATGPLSGSLPKNMAKIWVFDDMKCDDNGGRTYMVNVMPGQDRCLAFTNVGSIFSWFKSDIGKCEVSVHSGSNCKGWKWSTRNKACSSGHFASVRVNCPKA</sequence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688412.1">
        <property type="nucleotide sequence ID" value="XM_007690222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z550"/>
    <dbReference type="GeneID" id="19128868"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96523"/>
    <dbReference type="eggNOG" id="KOG0591">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029540_0_0_1"/>
    <dbReference type="OrthoDB" id="3693843at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF98">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="228"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC45110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="630" mass="72298" checksum="B5EBF3FA0FD6FC0B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5E7</accession>
    <name>W6Z5E7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fork-head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_102605</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964049">
        <property type="protein sequence ID" value="EUC42789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690706.1">
        <property type="nucleotide sequence ID" value="XM_007692516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5E7"/>
    <dbReference type="STRING" id="930090.W6Z5E7"/>
    <dbReference type="GeneID" id="19118113"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102605"/>
    <dbReference type="eggNOG" id="KOG2294">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_597367_0_0_1"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881:SF5">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="8">
        <location>
            <begin position="176"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="176"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="261"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="286"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="452" mass="50616" checksum="D9F65A7FD4779E47" modified="2014-04-16" version="1">MNFDEQQQRMPRPVPAGFGFSPATQSGDAYHAANGFSSAPGHGYHYPQHGMSYESNYKLTCPAQYSAATCPRSYNAFNSSGLPHDLSVPDSFPPNAYHIEPPKHHDAMDPSDHEIKSQLMQLSNDYDHPQYPCPIKVEDYNHYQSPYSHPAQGSAPHDKTLRHTRDPDTGDAGIFDREQPYAQLIYRALLNAPNHTMILRDIYDWFRKNTDRASSSETKGWQNSIRHNLSMNGAFEKVDQPGDEARRGFMWRLTEQAIREGVKSTTRYRSKQPNKRSNRTHQPQPQRQASGAKGGQAARRAARLKRSAHMHEAYLSAQPMSRSVPTAFDPSYHRYGFPSSVPPSPYTGSETDFGYTSQNSDFPDSPIPDGCNMDLFSSASSYMGSPMSQGMPITDTAYLLHQSSSDSIFTHSSSPTADEPRTPLDQAVWQDDIATGPSCMFDDQLVYRENTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z614</accession>
    <name>W6Z614_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_96126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688249.1">
        <property type="nucleotide sequence ID" value="XM_007690059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z614"/>
    <dbReference type="GeneID" id="19128796"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96126"/>
    <dbReference type="eggNOG" id="ENOG502QTEV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049945_0_0_1"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="45526" checksum="62922862F734EBDC" modified="2014-04-16" version="1">MPAQPSAQEVATTLLAEKGLEVESLERIQSLWAGYGEICRVNIVPDPASTASSTEHQSFVLKLVTPPPTKADDEGHTRKILSYRVEQYFYTHLAPQMPDSLPVAKCVASINKLNEDGTSITAMLLSDLKQQYPIAGEKRAVLSQTQVFAALDWLSGFHGFWWSRVQNLTPSSLVLPPLEEVQRNDQNTEERSVWLNGGYTYLTTRRKEYTSLAMDHHSEWGVPLTRRINDEDLSIAEMAALFLAPKTPENPSISQYQTLIHGDVKSENLFTSAPGDQVAFYDFQYTGLGLGVCDLAKYFTCSVPLAMLVADEHVPQELAMQEGEEQLLRRYWEKLCETGGREYDWAIFVRHWEIALVDWLRFQASWGFWGNTEWLEARVRSVLGDEEWRRFVVDNVARVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z734</accession>
    <name>W6Z734_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_5027</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687655.1">
        <property type="nucleotide sequence ID" value="XM_007689465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z734"/>
    <dbReference type="STRING" id="930090.W6Z734"/>
    <dbReference type="GeneID" id="19124472"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5027"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003954_1_1_1"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045033">
        <property type="term" value="P:peroxisome inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000011">
        <property type="term" value="P:vacuole inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000397">
        <property type="entry name" value="Serine/threonine-protein kinase KIN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="248"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="212"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="564"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="51"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="602"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="663"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="701"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="722"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="774"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="810"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="854"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="879"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="908"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="935"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="991"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1037"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1093"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1112"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC45790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1121" mass="121402" checksum="3BBAB7CC712AD7B9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7S4</accession>
    <name>W6Z7S4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_94492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689502.1"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG0806">
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    <dbReference type="HOGENOM" id="CLU_030130_1_0_1"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050152">
        <property type="term" value="F:omega-amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043605">
        <property type="term" value="P:amide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006528">
        <property type="term" value="P:asparagine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.110.10:FF:000002">
        <property type="entry name" value="Nitrilase family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088">
        <property type="entry name" value="NITRILASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088:SF30">
        <property type="entry name" value="OMEGA-AMIDASE NIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886552" description="CN hydrolase domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="4">
        <location>
            <begin position="9"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC45813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="297" mass="32845" checksum="2E192ABE5651ED02" modified="2014-04-16" version="1">MTSILKKSLKLALIQLASGADKAANLTSARQKVLEASKAGAKLVVLPECFNSPYGTKYFDKYAETLRPSPPPESQSQTFHALSKLARDAGVYLVGGSIPERDEHDSKKLYNTSLTFAPSGELIATHRKVHLFDIDIPGKIRFKESEVLSPGNKITLVELPEYGKIAIAICYDIRFPELATIAARKGAFLLLYPGAFNLTTGPLHWELLARARATDNQVYVGLCSPARNMEAEYNAWGHSMVVDPNAQVMEQLDEKEGVLMQELEAGKIEEVRKGVPLYGQRRFDVYPDVSEGGRFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z874</accession>
    <name>W6Z874_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA primase</fullName>
            <ecNumber evidence="9">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_3070</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic-type primase small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="9"/>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685467.1">
        <property type="nucleotide sequence ID" value="XM_007687277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z874"/>
    <dbReference type="STRING" id="930090.W6Z874"/>
    <dbReference type="GeneID" id="19121720"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3070"/>
    <dbReference type="eggNOG" id="KOG2851">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028288_1_0_1"/>
    <dbReference type="OrthoDB" id="19606at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04860">
        <property type="entry name" value="AE_Prim_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.920.10:FF:000002">
        <property type="entry name" value="DNA primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.920.10">
        <property type="entry name" value="DNA primase, PRIM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002755">
        <property type="entry name" value="DNA_primase_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014052">
        <property type="entry name" value="DNA_primase_ssu_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00335">
        <property type="entry name" value="primase_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10536">
        <property type="entry name" value="DNA PRIMASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01896">
        <property type="entry name" value="DNA_primase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56747">
        <property type="entry name" value="Prim-pol domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="496" mass="56459" checksum="593EBFB1CE7564B2" modified="2014-04-16" version="1">MPHSISPDSTPAQDAPQTDNVKPEPETQDVAMEDVPAAATSETSKVKLEEIFDDVDSDPEFPSSAPVPTSQEDASQPAPIKINSKSSFSDPDIMRAFYQRLFPFRPLFQWLNHSVTPSNDFAHREFAFTLPNDAYLRYQSFPTSDLLRKQCISMLPSRFEIGPMYSTNPRDRKTLRKASAFRPVMKELVFDIDMTDYDDIRTCCTGASICLKCWGFITMAIKTIDVALREDFGFKHILWVYSGRRGAHAWVCDKRAREMDDQRRRSVASYLELLKGGDQGGKKVHARRPLHPHLERSLEILKEHFQTSILAEQDPWASDEKAAHLLNLLPDPTLKAALQKKWSAAPSRPSASKWSDINTLAESGALSKTPRELREAKQDIILEYTYPRLDAEVSKKLNHLLKSPFVIHPGTGRVCVPIDTRKVEDFDPLSVPTVTQLLQEIDDWTGDETDKKVQDWEKTSLKPYVDFFKRFVAGLLEEEKPALKREREEAADTMEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8Y1</accession>
    <name>W6Z8Y1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein BFR2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_25446</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AATF family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686948.1">
        <property type="nucleotide sequence ID" value="XM_007688758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8Y1"/>
    <dbReference type="STRING" id="930090.W6Z8Y1"/>
    <dbReference type="GeneID" id="19120761"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25446"/>
    <dbReference type="eggNOG" id="KOG2773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018299_2_2_1"/>
    <dbReference type="OrthoDB" id="5783963at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025160">
        <property type="entry name" value="AATF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039223">
        <property type="entry name" value="AATF/Bfr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012617">
        <property type="entry name" value="AATF_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15565">
        <property type="entry name" value="AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15565:SF0">
        <property type="entry name" value="PROTEIN AATF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13339">
        <property type="entry name" value="AATF-Che1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08164">
        <property type="entry name" value="TRAUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AATF leucine zipper-containing" evidence="5">
        <location>
            <begin position="194"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Apoptosis-antagonizing transcription factor C-terminal" evidence="4">
        <location>
            <begin position="379"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="474"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="495" mass="54865" checksum="1C07261F4BCADD79" modified="2014-04-16" version="1">MKKSKTRDFDPESLLDPAPSSSEDERSGSDISDVEDEKVGREHYTAVGKSKLRKPVEVPLGPEYTGRKVDRKALEDSDSDDPFARGFDDEDSEASDEEGEDDINDAELGSEDESGGSDADGGLDLDMSDEDEEIRSSAEDVSDDEEDEEDEEDSEASDEDQPSKDKKPDVSAVRDLMAASKSFTSTIAAGTQSDVAKGEAVKTQRKTFDTLLNSRIRLQKALISTNSMAAEPYHNETVQEAPVEAAEAAALTLLNNLTNLRLSLEESRTGQKRKRANFDHATPSSEIWSTIQDTEKSTLPHRKAILERWSNKTKATTVTNNKARLNASAQQTLTEVLDSQLKSSHLVTRTQTPRSCAPLQSSNKAAQPDPAIYDDADFYGLMLKELLEQRSADLNANGTAEFVVQAPWQVAREAKTKKIVDTKASKGRKLRYTVQEKLQNFMAPEDRGEWGDRQRDELFGSLFGQRLGLREHDEVESEEEEQVDAEEAGLMLFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z921</accession>
    <name>W6Z921_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="5">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_4433</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="5"/>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686942.1">
        <property type="nucleotide sequence ID" value="XM_007688752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z921"/>
    <dbReference type="STRING" id="930090.W6Z921"/>
    <dbReference type="GeneID" id="19124232"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4433"/>
    <dbReference type="eggNOG" id="KOG0856">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_8_1_1"/>
    <dbReference type="OrthoDB" id="44061at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00357">
        <property type="entry name" value="peptide-methionine (R)-S-oxide reductase MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081:SF8">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MsrB" evidence="6">
        <location>
            <begin position="77"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="204" mass="22451" checksum="C50B2D83B4295C2E" modified="2014-04-16" version="1">MRFPSFPTFLRTIHTVTNTTTAFLRSSPATGIGRTIYNTPQRAVLYRSMPNIPFLGALFGSSSSMSDNTNYPVQKPEGEWQAQLSPEQFRILRKKGTEPPGSGKYDKHYPDAGVYTCGGCDAPLYKANHKFDSGCGWPAFWDAIPGAVGQKPDPGLGMMRTEIVCNNCGGHLGHIFKGERFGNPKDERHCVNSISINFSPEDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9L2</accession>
    <name>W6Z9L2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_58567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685064.1">
        <property type="nucleotide sequence ID" value="XM_007686874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9L2"/>
    <dbReference type="GeneID" id="19124758"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_58567"/>
    <dbReference type="HOGENOM" id="CLU_169364_0_0_1"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="116" mass="13537" checksum="55642F9CE0A455A9" modified="2014-04-16" version="1" fragment="single">SFVEMTPPPSRKRSLNSHLDTPTRARFFQAIDQRGDKTKRDIYHEFNIPHATAYRLLQQRDKYGKLADRRSKLRQYKKEHGGIGSGRPRKDSNNKTPQQMHNARLTIPTSKVEHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA25</accession>
    <name>W6ZA25_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_27262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689071.1">
        <property type="nucleotide sequence ID" value="XM_007690881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA25"/>
    <dbReference type="STRING" id="930090.W6ZA25"/>
    <dbReference type="GeneID" id="19121090"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27262"/>
    <dbReference type="eggNOG" id="ENOG502RS28">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1461059_0_0_1"/>
    <dbReference type="OrthoDB" id="3691236at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="185" mass="20623" checksum="9C9C20708155C693" modified="2014-04-16" version="1">MHDESGCANYNGEAALQLSAGLVPKLKHVCMWENIRIPSREITRQKPIRPQWQGLHPQSDSEWREMPQTKDAIQGLAIHAFLPLTLKRTGYREEDGQNAPCIRMLPLNDGKDQEAMAITMRQVLINAAVYESLAQSIFQQMPVTHTLVEVGLPPKLDFAFLHGWGEAGYAGVTLEAHQTLQGQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB06</accession>
    <name>W6ZB06_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospholipase</fullName>
            <ecNumber evidence="5">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_27082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the phospholipase D family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="5"/>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44654.1"/>
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        </source>
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            <dbReference type="EMBL" id="EUC44654.1"/>
        </source>
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        <source>
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        </source>
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</entry>
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    <accession>W6ZBA6</accession>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
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        <location>
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            <end position="458"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="969" mass="111300" checksum="DA356812040A9413" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCV4</accession>
    <name>W6ZCV4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LITAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_33076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCV4"/>
    <dbReference type="GeneID" id="19122238"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33076"/>
    <dbReference type="eggNOG" id="ENOG502SDXG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143602_0_0_1"/>
    <dbReference type="OrthoDB" id="4506934at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17527" checksum="91CB9CBECC311D47" modified="2014-04-16" version="1">MGIPTTPTEAAPAYDDVINNHPTNRYMPSGSLSGYTTIPQSDEADHPPFARETSDIEHHAHTTTTSSPPPPPPSQQQQQPETFAQTITKLLLPQPDSQHKHCAVCDEQVHTAARQKRESERYRCTVVAVTFITLFMCGMVLGVVIVNASARRSREGNGGH</sequence>
</entry>
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    <accession>W6ZDI6</accession>
    <name>W6ZDI6_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="5" type="ORF">COCMIDRAFT_88979</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDI6"/>
    <dbReference type="STRING" id="930090.W6ZDI6"/>
    <dbReference type="GeneID" id="19127388"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88979"/>
    <dbReference type="eggNOG" id="ENOG502S225">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_414547_0_0_1"/>
    <dbReference type="OrthoDB" id="608866at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052450">
        <property type="entry name" value="TRBD-Containing_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734:SF1">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1 TERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="275"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="275"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="494"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="554"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="656"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="513"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="666"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="720" mass="78305" checksum="AAA874691EE7D9A2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDT8</accession>
    <name>W6ZDT8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carbonic anhydrase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_32584</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683402.1">
        <property type="nucleotide sequence ID" value="XM_007685212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDT8"/>
    <dbReference type="STRING" id="930090.W6ZDT8"/>
    <dbReference type="GeneID" id="19122132"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32584"/>
    <dbReference type="HOGENOM" id="CLU_2003506_0_0_1"/>
    <dbReference type="OrthoDB" id="3669623at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175:SF3">
        <property type="entry name" value="CARBON DISULFIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601765-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="15514" checksum="46A855045AF3ABEE" modified="2014-04-16" version="1">MSIPGNLVVITCNEANPIIDPARHFNLNTSTTRVIRTAGGRTEGAISSIYQVAQSVKIDMIIVVQHTSCPWLPGEVENNIRSDIQGLKASPYIQDDISIIGYVLDLATDRLREVNVPRTGPGAEARQHVLDQMKDFGPFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDX3</accession>
    <name>W6ZDX3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_8635</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964090">
        <property type="protein sequence ID" value="EUC41711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691775.1">
        <property type="nucleotide sequence ID" value="XM_007693585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDX3"/>
    <dbReference type="STRING" id="930090.W6ZDX3"/>
    <dbReference type="GeneID" id="19126841"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8635"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020492_1_1_1"/>
    <dbReference type="OrthoDB" id="10029320at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11051">
        <property type="entry name" value="CYP59-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="61551" checksum="499D6B1571638A19" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE02</accession>
    <name>W6ZE02_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 43 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_94797</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687787.1">
        <property type="nucleotide sequence ID" value="XM_007689597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE02"/>
    <dbReference type="GeneID" id="19128516"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94797"/>
    <dbReference type="eggNOG" id="ENOG502QTYK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009397_4_1_1"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052176">
        <property type="entry name" value="Glycosyl_Hydrlase_43_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772:SF2">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC45689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="327" mass="36838" checksum="907AD28EED405A64" modified="2014-04-16" version="1">MSVQAYDPPIISTFHQCDPAAHVWKHDPNTVYIYGSHDWNSTRQPPVQYDMKDYYVLTQTDYTKPATVGPKLLDLTDIPWASQQLWAPDATEKDGYYYLFFPAKDKDDVFRIGVAKSDKPDGKFKPEPNPIPGTYSIDPTVLQDGHDYYMLWGGLWGGQLQAWTNNTLNTSAFGNISPTSGPAIGPRFAKLSANLTSLATTPKELVIYDQDGKVMQADSPRRYFEAPSLNKVGNLYILQYSTGTSHTIEIATATKPDGPYYWKNTLLQPVKGWTTHESIVKFKNDWLLYYADSSLSGRDDLRNTKVRKVLFEDGTFKLAQPQPVVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE12</accession>
    <name>W6ZE12_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nicotinate-nucleotide pyrophosphorylase [carboxylating]</fullName>
            <ecNumber evidence="5">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_40123</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>nicotinate beta-D-ribonucleotide + CO2 + diphosphate = quinolinate + 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Hexamer formed by 3 homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="5"/>
    <dbReference type="EMBL" id="KI964088">
        <property type="protein sequence ID" value="EUC41751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691734.1">
        <property type="nucleotide sequence ID" value="XM_007693544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE12"/>
    <dbReference type="STRING" id="930090.W6ZE12"/>
    <dbReference type="GeneID" id="19123816"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40123"/>
    <dbReference type="eggNOG" id="KOG3008">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026521_0_0_1"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034213">
        <property type="term" value="P:quinolinate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000090">
        <property type="entry name" value="Nicotinate-nucleotide pyrophosphorylase [carboxylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.20:FF:000003">
        <property type="entry name" value="Nicotinate-nucleotide pyrophosphorylase [carboxylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="entry name" value="Quinolinate phosphoribosyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179:SF3">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54675">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GH16" evidence="12">
        <location>
            <begin position="292"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC41751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="646" mass="69772" checksum="43DF5C1B2D190A42" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE81</accession>
    <name>W6ZE81_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein phosphatase 4 core regulatory subunit R2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_36498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP4R2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687669.1">
        <property type="nucleotide sequence ID" value="XM_007689479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE81"/>
    <dbReference type="GeneID" id="19123048"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36498"/>
    <dbReference type="eggNOG" id="ENOG502SBSZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024587_2_0_1"/>
    <dbReference type="OrthoDB" id="341898at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015267">
        <property type="entry name" value="PPP4R2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487">
        <property type="entry name" value="PPP4R2-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09184">
        <property type="entry name" value="PPP4R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="43613" checksum="B710C28051B01EF5" modified="2014-04-16" version="1">MPSAESILHQAAEHGSLDSAEWPATLQYILQRLDEIVAEFPKPPTDTTPNPPASAITDLPSRPGTSNALSSQDSHATDKENAPPATPPRPPVPSFSAATEPQGIPADINTFYSAIRTTLSKNFPKHPPHTIQRLAELILEPKKRYRFLPPYLRALDRVVSVSSPLTVFPLPQAVLPTASGLLNGATSSTASQPAPLGSDESLGGALLTPIPWLQNRGQNELISESTEMVDGPNGAGRIETVTVGMLANTAQPENPTSVAQIASSHPDGETLPSTGPVTQGELLRQEQEAGIVLNNPHSITSNSAKTTFGDVQGGPSIMETVESEEEIPHARGPEIIGMEDTGPQHDGKLNIEGAVGRPSLDRKTPEPSASKDNESSQGGAENDGAKEGSDESKEGTAAGETGTEKRDVEMKSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZED6</accession>
    <name>W6ZED6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate esterase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_36470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687628.1">
        <property type="nucleotide sequence ID" value="XM_007689438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZED6"/>
    <dbReference type="GeneID" id="19123039"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36470"/>
    <dbReference type="eggNOG" id="ENOG502S0SQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015101_4_2_1"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889947" evidence="2">
        <location>
            <begin position="18"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="324" mass="35614" checksum="A898C4C2723920AA" modified="2014-04-16" version="1">MVKSIALALSLATTSLAASEAQASSWSGWKNVKHLFVFGDSYTQTGFNVNGTQPSPSNPLGNPPYPGWTSSNGPNWVGFLTTTYNASTLLTYNMAYGGATVSSDLVAPYTPTVVSMKEQVQSQFLPTYGSHPDFAPWTSDSSLFAFFIGINDVGTSWWRDNSSALWDTIFTVYEKQLTDIYATGGRNFLFLNVPPVNLAPLTTQQNDGGYAVEHEGKAIEDWNKRITNMVSGFQAKNTGTTAFVYDTWALYNSVIKNPASYKQTADLKNVTGYCNAYKNGTPTWYTKDPSCQYPVNEYLWLNELHPTFSINNATAASIVELLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEG2</accession>
    <name>W6ZEG2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_94259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_94259"/>
    <dbReference type="HOGENOM" id="CLU_176410_0_0_1"/>
    <dbReference type="OrthoDB" id="10279866at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889949" evidence="1">
        <location>
            <begin position="19"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="106" mass="11464" checksum="535C0E645F78F7F3" modified="2014-04-16" version="1">MKFNSLAAIFILAGIASANTACQCNIIDPSKYSIEGGTRVTCHGTITVNHQKLAGRMIPGDRCLLNTDGLNLPLDKIQKQYSQDCARINIADVTPWPNATCQVSQD</sequence>
</entry>
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    <accession>W6ZEZ7</accession>
    <name>W6ZEZ7_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">VIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_23746</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEZ7"/>
    <dbReference type="STRING" id="930090.W6ZEZ7"/>
    <dbReference type="GeneID" id="19120487"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23746"/>
    <dbReference type="eggNOG" id="ENOG502QRPK">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003826_2_0_1"/>
    <dbReference type="OrthoDB" id="1729737at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
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            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="288"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="775"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="708"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="931" mass="101644" checksum="515109169CD6EAD1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF16</accession>
    <name>W6ZF16_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HAUS augmin-like complex subunit 3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_86766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_86766"/>
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    <dbReference type="OrthoDB" id="5314201at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="249"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="472"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="57704" checksum="9779051E85F59AC8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFJ8</accession>
    <name>W6ZFJ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_103933</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
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        <property type="protein sequence ID" value="EUC42256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFJ8"/>
    <dbReference type="GeneID" id="19118409"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103933"/>
    <dbReference type="eggNOG" id="ENOG502QS4K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036005_1_0_1"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF10">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="2"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="315" mass="35370" checksum="5E6691F73D55484B" modified="2014-04-16" version="1">MDLTPILGTEFVDARLAQWMSAPNADAMLRDLAIKISERGVVFFRGQDDLTNEMQKQLMQRLGELSGKPRTSSLHVHPVISSERTLADDLEISVISTELGSGRQMAAVNPGQWHTEIAFELVPADYTSLRLTKLPKTDTMWASGYEIYDRISHPYRRFLEGLTATFALPSINTATQRLGSSLYDGARGSPDNVGADLKAVHPVVRTNPVTGWKSIYPIGLHVSHINGVTPEESQNLCEWLLQMIYRNHDLQVRFKWQNKNDIAIWDNRSVFHAATFDFEGLGERLGDRAVGVGERPFFDPNSTSRRESLNLPSYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG38</accession>
    <name>W6ZG38_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_80865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682753.1">
        <property type="nucleotide sequence ID" value="XM_007684563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG38"/>
    <dbReference type="STRING" id="930090.W6ZG38"/>
    <dbReference type="GeneID" id="19125753"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80865"/>
    <dbReference type="eggNOG" id="KOG2210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012334_0_1_1"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008142">
        <property type="term" value="F:oxysterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF92">
        <property type="entry name" value="OXYSTEROL BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="463"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="490" mass="54693" checksum="90EB01AE5F966E83" modified="2014-04-16" version="1">MSNDITHNRSILKEFLASIATISGDLSNITAPPFVLADNSTVEIPQYWADHPYLWAAPATEENPEKRALLVLKNFLCSLRGQQYGGRREEDGVKKPLNAFLGEVFLGGWNMEDLGETRLVSEQVGHHPPVTACYLWNNHVGIRAEGFTEQEITFNGNVAIKQNGYAIVHVDKYDEDYLLPLPSIKVKGLLSGVPHPELYGDYSLICSNGYISHIHFEGKSLLGFGQKNSFHARFFHKDNPSDIIYILEGTWNSTFTIKDARSDTEIETCDVRSIKQQPMTVPDLSEQDPWESRKAWQHVISALRRGDMRGVVKAKSEVENGQRQMRKDEQAKGETFTSIFFKRVDKDPIFEELVQYDPQGFTIDPKAGIWKVDKEAAENKSRPFHGDLTPSNQRTSNLQPHSRQHRPPPQNNRNNSTAASGQGPQCGGTEMETAADSINGATEPRGRPAPSSPSDSSPRNAATEATTHSPVEPSNQQVEDFLRAKTGNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGC0</accession>
    <name>W6ZGC0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MADS-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_35783</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686890.1">
        <property type="nucleotide sequence ID" value="XM_007688700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGC0"/>
    <dbReference type="STRING" id="930090.W6ZGC0"/>
    <dbReference type="GeneID" id="19122869"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35783"/>
    <dbReference type="eggNOG" id="KOG0015">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063931_1_0_1"/>
    <dbReference type="OrthoDB" id="2284405at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00266">
        <property type="entry name" value="MADS_SRF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1810.10:FF:000002">
        <property type="entry name" value="Serum response factor b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050142">
        <property type="entry name" value="MADS-box/MEF2_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033897">
        <property type="entry name" value="SRF-like_MADS-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48019">
        <property type="entry name" value="SERUM RESPONSE FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00350">
        <property type="entry name" value="MADS_BOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="7">
        <location>
            <begin position="50"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="130"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="219" mass="24228" checksum="F05B00A9D774514E" modified="2014-04-16" version="1">MASEITEHDQNASPSVHDDGNGSLGMENRGVKRARAAADDDDDDDDKPGRERRKIEIKFIQDKSRRHITFSKRKAGIMKKAYELSVLTGTQVLLLVVSETGLVYTFTTPKLQPLVTKPEGKNLIQACLNAPEPSSGDANGVDNDTVESPEDNHAQVPPGQPRMPPNNQAMPQAYMTPEAALHYQSYLQQQQQQSNQYPMAQQGMPRHPGGHYPQDQKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGD3</accession>
    <name>W6ZGD3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964057">
        <property type="protein sequence ID" value="EUC42556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690925.1">
        <property type="nucleotide sequence ID" value="XM_007692735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGD3"/>
    <dbReference type="GeneID" id="19123677"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39398"/>
    <dbReference type="HOGENOM" id="CLU_526754_0_0_1"/>
    <dbReference type="OrthoDB" id="10442703at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="549" mass="58288" checksum="487660DFE896C50D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHG0</accession>
    <name>W6ZHG0_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_102119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964043">
        <property type="protein sequence ID" value="EUC42991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHG0"/>
    <dbReference type="GeneID" id="19118012"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102119"/>
    <dbReference type="eggNOG" id="ENOG502SBKV">
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    <dbReference type="OrthoDB" id="6222486at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09271">
        <property type="entry name" value="RNase_H2-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013924">
        <property type="entry name" value="RNase_H2_suC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204">
        <property type="entry name" value="OS02G0168900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204:SF1">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08615">
        <property type="entry name" value="RNase_H2_suC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="165" mass="18166" checksum="59A34B5602ABDD71" modified="2014-04-16" version="1">MLAIQPSKPQKCTPNLLPARINHNGPIPSTPQYWKPSTDDKGTQHAHFRGRHLHGTVVPLPENYTGTILAVTEKQLPQSRQPAQSDGDETMEDKEEESIPVEVKIAEQVGEFDEVVVWGHGGEVDSGQDMFVKGLKEWVGFAESMHLDADGETVTEAETGKEKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI10</accession>
    <name>W6ZI10_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Urea active transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_1637</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683836.1">
        <property type="nucleotide sequence ID" value="XM_007685646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI10"/>
    <dbReference type="STRING" id="930090.W6ZI10"/>
    <dbReference type="GeneID" id="19119913"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1637"/>
    <dbReference type="eggNOG" id="KOG2348">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010778_2_1_1"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015489">
        <property type="term" value="F:putrescine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1730.10:FF:000006">
        <property type="entry name" value="Urea active transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF4">
        <property type="entry name" value="UREA ACTIVE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="503"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="582"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="612"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="662"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC49593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="692" mass="73493" checksum="4CC1C5D3081D430E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZII9</accession>
    <name>W6ZII9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Non-histone chromosomal protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_90970</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NHP6 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="HMGB"/>
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    </dbReference>
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        </location>
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        </location>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47189.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="111" mass="12669" checksum="666F680D1899BC69" modified="2014-04-16" version="1">MPKEKTTRKAAPKTKTEKKKKAADPNAPKRGLSAYMFFANEQREKVREDNPGIKFGEVGKLLGEKWKALNDKQRQPYEAKAALDKKRYEQEKAAYTVCLLPNPCNPKKITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ02</accession>
    <name>W6ZJ02_COCMI</name>
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    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_22343</name>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC50005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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    <accession>W6ZJ09</accession>
    <name>W6ZJ09_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">Glycoside hydrolase family 127 protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_38458</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502QRCI">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008033_2_0_1"/>
    <dbReference type="OrthoDB" id="5358475at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PROLINE-TRNA LIGASE (DUF1680)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31151:SF0">
        <property type="entry name" value="PROLINE-TRNA LIGASE (DUF1680)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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        <location>
            <begin position="20"/>
            <end position="620"/>
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    </feature>
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            <begin position="442"/>
            <end position="533"/>
        </location>
    </feature>
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        <source>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="620" mass="68332" checksum="E5AAB59A929281FD" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6ZJ23</accession>
    <name>W6ZJ23_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBL3-like ubiquitin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_90133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686013.1">
        <property type="nucleotide sequence ID" value="XM_007687823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ23"/>
    <dbReference type="STRING" id="930090.W6ZJ23"/>
    <dbReference type="GeneID" id="19127617"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90133"/>
    <dbReference type="eggNOG" id="ENOG502S95Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055856_0_0_1"/>
    <dbReference type="OrthoDB" id="1043111at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040015">
        <property type="entry name" value="UBL3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039540">
        <property type="entry name" value="UBL3-like_ubiquitin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13169:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13169">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13881">
        <property type="entry name" value="Rad60-SLD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBL3-like ubiquitin" evidence="2">
        <location>
            <begin position="160"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="258" mass="27907" checksum="79D14044E510008C" modified="2014-04-16" version="1">MSSPADQASTAPQTTPHQQTPGSRPQSRNEPPSTGSVEMKTLEASGATPAPTDTTTHTTDAPAVAPAAASAEQPVESSTSEDAPVVPSSPGKLTPPSALNRADTEAIGPSTDTPAANPDNTNGPVLVIMLLLTSGARHPYKIDEKYLKKRSVKVENMDPYNISVYTLKELIWRDWREEWEARPTSPGSIRLIHFGRMLDDKSPLKAECRFQTDTPNVVHMTVKPQEVVDEEENAKIGKSGNRRESDDEPTATCRCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKT2</accession>
    <name>W6ZKT2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphorylcholine phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_88053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685335.1">
        <property type="nucleotide sequence ID" value="XM_007687145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKT2"/>
    <dbReference type="GeneID" id="19127190"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88053"/>
    <dbReference type="eggNOG" id="ENOG502SEU8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062627_0_0_1"/>
    <dbReference type="OrthoDB" id="5182398at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050582">
        <property type="entry name" value="HAD-like_SerB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890101" description="Phosphorylcholine phosphatase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="40569" checksum="183BE154235D8956" modified="2014-04-16" version="1">MRTSTLNTALWLAFASSFGAATPYYGAHHKTQLKHWPADAAKALNTMIARNANQSNYAVFDMDNTSWRYDIEESLLPFLENRGILKRENLDPSLKLVDFKDTANFTESLFSYYNRLCDIDTFLCYPWAAQVWSGFTLRELKGYVDELMAYNSTIPTKYWDGDEVISSSVHTPQVFRGQAELYNALMENGIAVYIMSASHEELVRMVASDPKYGYNVPPENVIGVTTVLKNTTSGAVTNAREQITAGTYNETANLDLVVTPYLWTPATWYAGKWAGILTYIDQWKRPILVGGDTPGSDSYMQFHGVDVSKGGIHLWINRKDSYFKQLQEEIKNNTLAQIANGREVTADKNWVVVKPEEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLC9</accession>
    <name>W6ZLC9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_81025</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682738.1">
        <property type="nucleotide sequence ID" value="XM_007684548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLC9"/>
    <dbReference type="GeneID" id="19125785"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81025"/>
    <dbReference type="eggNOG" id="ENOG502RXX5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005807_1_0_1"/>
    <dbReference type="OrthoDB" id="4090074at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070860">
        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001179">
        <property type="term" value="F:RNA polymerase I general transcription initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001163">
        <property type="term" value="F:RNA polymerase I transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019350">
        <property type="entry name" value="RNA_pol_I-sp_TIF_RRN6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048535">
        <property type="entry name" value="RRN6_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048537">
        <property type="entry name" value="RRN6_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048536">
        <property type="entry name" value="Rrn6_K-rich"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28221">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28221:SF2">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10214">
        <property type="entry name" value="Rrn6_beta-prop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20640">
        <property type="entry name" value="Rrn6_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20639">
        <property type="entry name" value="Rrn6_K-rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRN6 beta-propeller" evidence="2">
        <location>
            <begin position="110"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="RRN6 helical bundle" evidence="4">
        <location>
            <begin position="550"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="RRN6 K-rich C-terminal" evidence="3">
        <location>
            <begin position="846"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="859"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="947"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="875"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1172" mass="129873" checksum="E235926F49AB2A6B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLJ3</accession>
    <name>W6ZLJ3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_34076</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685021.1">
        <property type="nucleotide sequence ID" value="XM_007686831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLJ3"/>
    <dbReference type="STRING" id="930090.W6ZLJ3"/>
    <dbReference type="GeneID" id="19122477"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34076"/>
    <dbReference type="eggNOG" id="ENOG502SB89">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018728_0_0_1"/>
    <dbReference type="OrthoDB" id="2015405at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042602">
        <property type="term" value="F:riboflavin reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050268">
        <property type="entry name" value="NADH-dep_flavin_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30466">
        <property type="entry name" value="FLAVIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30466:SF1">
        <property type="entry name" value="FMN REDUCTASE (NADH) RUTF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="3">
        <location>
            <begin position="129"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="808" mass="92081" checksum="BD8829716C08F6BE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLJ7</accession>
    <name>W6ZLJ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_32049</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682705.1">
        <property type="nucleotide sequence ID" value="XM_007684515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLJ7"/>
    <dbReference type="GeneID" id="19122017"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32049"/>
    <dbReference type="eggNOG" id="ENOG502S56Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065618_2_2_1"/>
    <dbReference type="OrthoDB" id="4094614at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052982">
        <property type="entry name" value="SRP1/TIP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633:SF1">
        <property type="entry name" value="GPI ANCHORED SERINE-THREONINE RICH PROTEIN (AFU_ORTHOLOGUE AFUA_1G03630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889927" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="3">
        <location>
            <begin position="36"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="250" mass="24621" checksum="6EEE19DE4E4957F6" modified="2014-04-16" version="1">MYSKATIVSIFAGFAAAQIHPAVGDPKGNPITRPLNEIVPKCEPFTITWEPTTPNSVSVLLLKGPSTNVVKFGPSLAEGIKNSGSLTWTPAADLPVTEANQGYGLQIIDDVTGQYQYSTQFGISAGKCGSVVSSSAAPSVAPSSAPAAGYPASSAPAAYPASSAPAAGYPAHTPVAPSSAASVAPYPTTLASAPAAVGTGGLYPNGTVPKPTGANSTTPPLPEQTTNAAAGLSAGLGLVGAAAAVVAFML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLQ7</accession>
    <name>W6ZLQ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_80232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682387.1">
        <property type="nucleotide sequence ID" value="XM_007684197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLQ7"/>
    <dbReference type="STRING" id="930090.W6ZLQ7"/>
    <dbReference type="GeneID" id="19125628"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80232"/>
    <dbReference type="eggNOG" id="ENOG502QQNB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033094_0_0_1"/>
    <dbReference type="OrthoDB" id="1461976at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="82"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="404" mass="45975" checksum="A65B7B8920EEE446" modified="2014-04-16" version="1">MITTTHRVHEAPVKTRLTAVADVRPIPDVKTLKDAIPAKCFERSMLRSFSYVVRDLIVVFSLFYAAVPLSRLDAPWFVTVPLWALYSFVQGCFFTGLWILAHDCGHDSFSENLTVNAITGWFLHCMLMVPFFSWKFSHARHHRYHNHMDKDTVFVPHRKSDVEAKKTKPTIFDKIMDHSAADTPIITVASLIFHQVLGWPAYILMNAGAGKKSLTKGDRYTSSRYKQSHLDPTAHVFTLSEAPFVALSNVGLILTMTALYVWSRSVGTSTVLLAYGLPYLWMNHWIVAITYLHHTHPEAPHYEADNWTFIKGAASTVDRDFGFIGRHIFHGIIEYHVVHHMFPRIPFYHAEEATWAIAPLLGERYIQQKTNFFGDLWQSFTTCKTVEPGTGVHAGGLVWSKTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLR8</accession>
    <name>W6ZLR8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7888 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_79997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682392.1">
        <property type="nucleotide sequence ID" value="XM_007684202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLR8"/>
    <dbReference type="GeneID" id="19125579"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79997"/>
    <dbReference type="eggNOG" id="ENOG502SB2X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105121_1_0_1"/>
    <dbReference type="OrthoDB" id="3478218at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057210">
        <property type="entry name" value="DUF7888"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40845">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40845:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25411">
        <property type="entry name" value="DUF7888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7888" evidence="1">
        <location>
            <begin position="6"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="123" mass="13611" checksum="68F57A0B7542076E" modified="2014-04-16" version="1" fragment="single">ASIAGAMSGLLQKLFPISNWTSARETFTKATVDAMWARNPDRKRWVAAACYNMKWDVANRAGISDVASVKLSMGALNTDYDCFYIGRHNALWTRGDGGYVNLAIVSDNGFCRFDSRTSDLDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLS1</accession>
    <name>W6ZLS1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycoprotease family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_80465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682590.1">
        <property type="nucleotide sequence ID" value="XM_007684400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLS1"/>
    <dbReference type="STRING" id="930090.W6ZLS1"/>
    <dbReference type="GeneID" id="19125673"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80465"/>
    <dbReference type="eggNOG" id="ENOG502SB2Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004045_0_0_1"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="609"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="747"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="525"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1016" mass="110630" checksum="60AA6FAC1B6C7D5F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMS8</accession>
    <name>W6ZMS8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_23392</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684604.1">
        <property type="nucleotide sequence ID" value="XM_007686414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMS8"/>
    <dbReference type="GeneID" id="19120423"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23392"/>
    <dbReference type="eggNOG" id="ENOG502SAH5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031491_2_0_1"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="429" mass="48534" checksum="FEF2B4A7461EFBE3" modified="2014-04-16" version="1">MPAPLVPVRRFKCTYKDCNMSFDTEKQMRSHKKCSDEHEYCHKCDEDFDSFKDYAMHKITRPAEHGRACRVCGDEFKSTSGLNRHIELNHKVDQKLTCIGCHESFYSAALFIEHLEFGHCGVISASQFQGHIVHKHLISELLKCGPALDRFRQKTSKFDAAIDYEEEGGVILDGPLDDDKEIEAVDFKAIEPDTTLTPAMADLSLHPKGVPRPSSPKQKVWVSRKEKPTAATLFPDAKPNPPKDFSISAHDAAMEQEHGINILRSRFWDPMSTDWNPEKFYDAIVGKYHCPFVCEQTFDCVGDLNKHILGEHRVTRMKCPKCLKHFNSATALMSHCESQGARCQINKADDFNIFLDRLSGGFLSVEEKTRPDHLNTRNVLVRDGVTGHMEMYMPPVASYLEYTVTTPPDWKEPAGPTVQVGGSSQTSPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMU3</accession>
    <name>W6ZMU3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_5854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688568.1">
        <property type="nucleotide sequence ID" value="XM_007690378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMU3"/>
    <dbReference type="STRING" id="930090.W6ZMU3"/>
    <dbReference type="GeneID" id="19124755"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5854"/>
    <dbReference type="eggNOG" id="ENOG502QRK5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_8_6_1"/>
    <dbReference type="OrthoDB" id="3358371at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05251">
        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF26">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="1"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="327" mass="36029" checksum="5D4D8C2DA24DA92C" modified="2014-04-16" version="1">MTKTIAVIGVTGNQGSSVARVFLTDPNWKVRGIARDPSKPSAQKWASQGVDIVPGNLDDVTSLKQAFQGATVIFGGTDFWGHLNDPATQKLAVSQNRTPNEVAYDREVAQAKSIIDAAAANLETLERFVLSTLSEARKWSNGTIKWNLHFDAKAEAVKYLKSTYPELLAKTSFLHLGYYATNWKSFSGRPTKQEDGSFVVSLPMSGERKIPMADPVADTGHFTKALVESPPGIILSGAGSFISFNEWCEIFGRVNSVKCTFQTIPRKAMEEAMGPIYGLEIADMFEYFDKYGFDGGADVVFPWDLGVKVKYTTMEEYMKGEDWSSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNI2</accession>
    <name>W6ZNI2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_96341</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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</entry>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        </source>
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        </source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="317" mass="33723" checksum="28BC91FEBF1210FA" modified="2014-04-16" version="1">MAPNDKAGRVVFIGNIPYGGTEELIVETLGRVGQVNNFRLVYDKETGRPKGFGFAEFADADAAASAVRNLNDYDLMGRKLRVDWSNESGSGDNAPSSRDPNTQAPMGMNGQPAAVPPPAQPSSTLGPLPPGVELPPNLTCPDAISRTLSTLPPDQLLDILSQMKGLVMTDPAKATELLRQAPQLAYAIFQSLLLLQLVDPQILTSLVETSAAPAPMAQAPPVQPVQQAPPQVARPPVNYGGYPPQVAPTPPQPQAPAPQPYAQAPQPAPQAQPAALDQQALYAQVMALTPQQIDQLTPEYRAQIMQIRQMLMAGGRP</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
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                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="EMBL" id="EUC49709.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="399" mass="45205" checksum="4124EBB02BF2FC38" modified="2014-04-16" version="1">MIATTKYHRISKNLESLPCELHEDILIHLQFHQLIRLSSCAGPRLIWSLQHSLSSWHRYFSSPAAITSLQELLAITDTVAKHGFPPSRKHVDATTIYEQEWSLRFLKYKASEWGSDYSVVELRNLQTTEALTKHWLNHLSRMVTSVLGPIVPNDPSFPQLPASFPTPASLVSFLASYQRAREANAEALARQLEHLALLYEAHPTRFKMPFDPRSSPPSTLNATHIPSTMRSQARRIVNVARAGKWRRHKRFLHRFAWPGLVPYESCVQLFNGFVLRTGLLKGGKVEGAGELMEECRSVIEGRPVWAGDVRKGKEVEGKSEGDAIEELSSMMERQNLGADVTPIRIQVYIEDAKEDIRKVLVVPRAEMELQWLERFAQVTASLEQAYPDLEKDSLGPVPA</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZT13</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Wu D."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963960">
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688471.1"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="116" mass="12990" checksum="DC817346E6E4E4DA" modified="2014-04-16" version="1">MCLFGRISPVIVFAARKLNVTWLVVPDMTRPPMSDAMPRLFLNHFTPPWLYPVNMHCCLSPCVPGASILRGHILFFAATYGSVYCKYTCQQPLLSIITRLLSRHGALHAHAHGDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTA8</accession>
    <name>W6ZTA8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 92 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_4093</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685828.1">
        <property type="nucleotide sequence ID" value="XM_007687638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUT0"/>
    <dbReference type="GeneID" id="19120594"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24459"/>
    <dbReference type="HOGENOM" id="CLU_1383931_0_0_1"/>
    <dbReference type="OrthoDB" id="10526241at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="197" mass="20800" checksum="29AD279969CE4F20" modified="2014-04-16" version="1">MPPTYFPLATAGGRNAGCEHGRAWSFCRHRRPSRVRGASPLPAVPPRGPTCPSAHATQPASAPSPSKFCDRTGQDRIGQDSIHAYATLPYATLPYALPRSAASAAKQNRRGHSSPPKLQPCRAIRTLFLHVPLPLPPPPPITPIHAPFLHHARLASASVRGSTCTPVGKIPSPSPSPLPYSASPVPVVPGALLADRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZV95</accession>
    <name>W6ZV95_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_24391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685739.1">
        <property type="nucleotide sequence ID" value="XM_007687549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZV95"/>
    <dbReference type="GeneID" id="19120584"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24391"/>
    <dbReference type="HOGENOM" id="CLU_1731126_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="151" mass="16760" checksum="02D83EB1B717C72A" modified="2014-04-16" version="1">MACASTWRGVAVYYSRSTGIDAGVRWASCHCIYWQCSPPTCASFVIAFVVVTTTPEPTRTSPPPNDGVLQHIAPCKEHHRLQPPSVAISDYVTAFTSPTITPRRKDHRHVHPPHMRAKVTRGSSLHDNACLIEATPIDRFTVVQMLLQHCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZW44</accession>
    <name>W6ZW44_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_24095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685396.1">
        <property type="nucleotide sequence ID" value="XM_007687206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZW44"/>
    <dbReference type="GeneID" id="19120542"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24095"/>
    <dbReference type="HOGENOM" id="CLU_1805830_0_0_1"/>
    <dbReference type="OrthoDB" id="10361584at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="143" mass="15247" checksum="718C16D9E79E598A" modified="2014-04-16" version="1">MTPGTCGSTGAVLMPSLPRTHQGHSSTGAYYALSMAGSFHSVVVQAHLAGMGGGVKGASKTLSNTLQHPRRSHRSSDWTSSADRIFSFSCALYFPTSVISLQKNGLTNVEVVLTTQGKTDAETKEIMDKVREENQSATDQIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZW83</accession>
    <name>W6ZW83_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_88416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685452.1">
        <property type="nucleotide sequence ID" value="XM_007687262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZW83"/>
    <dbReference type="STRING" id="930090.W6ZW83"/>
    <dbReference type="GeneID" id="19127261"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88416"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_2_4_1"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF37">
        <property type="entry name" value="ABC1 FAMILY PROTEIN C10F6.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="176"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="409"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="668" mass="75906" checksum="B27C85DE1A5DE6AB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZ23</accession>
    <name>W6ZZ23_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684574.1">
        <property type="nucleotide sequence ID" value="XM_007686384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZ23"/>
    <dbReference type="GeneID" id="19126748"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85849"/>
    <dbReference type="HOGENOM" id="CLU_2637891_0_0_1"/>
    <dbReference type="OrthoDB" id="3673085at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="81" mass="8774" checksum="7BD6E127FDB8696A" modified="2014-04-16" version="1">MYSRSQTYAVVTTSKHSAQISHLPLQLGDLVPLPFSSFLSAQTPYTAHPHNLVSASDTRVSTGTHTNLPFSMHPQSGPVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZE5</accession>
    <name>W6ZZE5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase</fullName>
            <ecNumber evidence="4">1.1.1.302</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_1994</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27274"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27278"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HTP reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.302" evidence="4"/>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684268.1">
        <property type="nucleotide sequence ID" value="XM_007686078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZE5"/>
    <dbReference type="STRING" id="930090.W6ZZE5"/>
    <dbReference type="GeneID" id="19119982"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1994"/>
    <dbReference type="eggNOG" id="ENOG502RZWZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036590_5_0_1"/>
    <dbReference type="OrthoDB" id="5432at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050765">
        <property type="entry name" value="Riboflavin_Biosynth_HTPR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011:SF7">
        <property type="entry name" value="2,5-DIAMINO-6-RIBOSYLAMINO-4(3H)-PYRIMIDINONE 5'-PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_8G06820)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="Bacterial bifunctional deaminase-reductase C-terminal" evidence="13">
        <location>
            <begin position="36"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC49131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="276" mass="29453" checksum="4B93358996C90151" modified="2014-04-16" version="1">MTPTPVREALHFADAQSKQFIDYMPPFPSQTPTEKPFVTLTFATSLDSQLSIAPGVQTALSGPQSKSMTHFLRSKHDAILIGVGTAIADNPSLNCRIEGVGGYGGEGLIGQPRPIVVDPQGRWQFSVESKVFKLAKEGKGKAPFIITHVAPSDARRAVLESVGGKFLLLGPSPTQKSETTSSWHMILDALKEQGIQSVMIEGGGFVINDLLGPGPAYSLVDSVIVTIAPTWLGKGGVQVCPDGGSDRLPVTRLKDVKWIPLGEDVVLCGRPNMSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZS4</accession>
    <name>W6ZZS4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">tRNA (guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="7 9">2.1.1.216</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_85043</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:43140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10359"/>
            <dbReference type="Rhea" id="RHEA-COMP:10360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74513"/>
            <dbReference type="EC" id="2.1.1.216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="7 9"/>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684208.1">
        <property type="nucleotide sequence ID" value="XM_007686018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZS4"/>
    <dbReference type="STRING" id="930090.W6ZZS4"/>
    <dbReference type="GeneID" id="19126588"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85043"/>
    <dbReference type="eggNOG" id="KOG1253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010862_2_0_1"/>
    <dbReference type="OrthoDB" id="6349953at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160104">
        <property type="term" value="F:tRNA (guanine(26)-N2)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002940">
        <property type="term" value="P:tRNA N2-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.70:FF:000001">
        <property type="entry name" value="tRNA (guanine(26)-N(2))-dimethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="entry name" value="N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00308">
        <property type="entry name" value="TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631:SF3">
        <property type="entry name" value="TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="90"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="563"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="642" mass="70397" checksum="5ED952986E1541C1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W7A1X2</accession>
    <name>W7A1X2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_32602</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ATX1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683408.1">
        <property type="nucleotide sequence ID" value="XM_007685218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A1X2"/>
    <dbReference type="STRING" id="930090.W7A1X2"/>
    <dbReference type="GeneID" id="19122138"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32602"/>
    <dbReference type="eggNOG" id="KOG1603">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134973_3_1_1"/>
    <dbReference type="OrthoDB" id="689350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000008">
        <property type="entry name" value="Copper transport protein ATOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051881">
        <property type="entry name" value="Copper_transport_ATOX1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46365">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN ATOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46365:SF1">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN ATOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="78" mass="8389" checksum="1762AD044EFF5A1E" modified="2014-04-16" version="1">MTHTYKFNVAMSCGGCSGAIERVLKKLEGVESYNVSLENQTAEITAADSLDYDTVLEKIKKTGKTVKSGEADGEAKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3J4</accession>
    <name>W7A3J4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10 11">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 10 11">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_81558</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10 11">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 11">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 10 11"/>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682908.1">
        <property type="nucleotide sequence ID" value="XM_007684718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3J4"/>
    <dbReference type="GeneID" id="19125894"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81558"/>
    <dbReference type="eggNOG" id="ENOG502RXA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_0_0_1"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.180:FF:000001">
        <property type="entry name" value="Endo-1,4-beta-xylanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033119">
        <property type="entry name" value="GH11_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF3">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00777">
        <property type="entry name" value="GH11_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10 11" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887488" description="Endo-1,4-beta-xylanase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="14">
        <location>
            <begin position="31"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="126"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC50601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="221" mass="23715" checksum="09DBD66837D9D657" modified="2014-04-16" version="1">MVSFTSIITAAVAATGALAAPATDVSLVARQNTPNGEGTHNGCFWSWWSDGGARATYTNGAGGSYSVSWGSGGNLVGGKGWNPGTARTITYSGTYNYNGNSYLAIYGWTRNPLVEYYVVENFGTYDPSSQSQNKGTVTSDGSSYKIAQSTRTNQPSIDGTRTFQQYWSVRQNKRSSGSVNMKTHFDAWASKGMNLGQHYYQIVATEGYFSTGNAQITVSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W7A433</accession>
    <name>W7A433_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_80872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682767.1">
        <property type="nucleotide sequence ID" value="XM_007684577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A433"/>
    <dbReference type="GeneID" id="19125754"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80872"/>
    <dbReference type="eggNOG" id="ENOG502T5N9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_811338_0_0_1"/>
    <dbReference type="OrthoDB" id="3942472at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="41345" checksum="E97EE0127D59B189" modified="2014-04-16" version="1">MAPPSYARATASSTSKASPKSSRTTRDPEVVKSTPSPSSRKLTESPNNSTPTPQEKKKALKRPSTLTSHQKDTIHYKCDLYHITPKDASKPCFLSLLPSELRTQIYTYILPSTHYISPSWPSLSKPKHPTIPPLLHISRAIRIEAAYTYYTTTTFHFTVRNLDFSPVTRWLEDLAPQHRALLPRNHRGLEINVIPTVKSTFTYPPKGWLLDADMERHWRACQPFGNIYTVHGEAHKLHFVVFCRLAKWWRWWGALQLKGEVKCNYAFEQSPFANPFGIPDFLDEVVLRQFLRHHGCAVGMACVEKAWRRNRMAAAGMKGEGVKFLEALDRWYKDRWGEQESANEWNLRMEEAKKAVGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W7A457</accession>
    <name>W7A457_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_32036</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682702.1">
        <property type="nucleotide sequence ID" value="XM_007684512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A457"/>
    <dbReference type="GeneID" id="19122014"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32036"/>
    <dbReference type="eggNOG" id="ENOG502RZP2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039317_2_0_1"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="125"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="31925" checksum="693E35981FC1C4B7" modified="2014-04-16" version="1">MSQHSPSSYNVGYPPPQQTAGRKRSHPDDLPHDLTPTLEQQLNPYAQATGSVSLQHATQSYSIQQYPPPPSAPHSTLPPTHHHHLPSTHRNKRHHAMEGAPPSPSHHHGPPSVVGQEGMPAPAQRPRGPKLKFTPEDDQLLVDLKEKKNLTWKQIADFFPGRSSGTLQVRYCTKLKAKTTVWTSEMVDKLRNAMQEYENDRWRIVSSKVGSGFSPNACRDKAEELQAMELAQQEAQEEEHSQLQQQQQQQQQQQQQQQQPQPPRTYTPSQLGTGPSEPDARYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLF6</accession>
    <name>W6YLF6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_41569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964205">
        <property type="protein sequence ID" value="EUC40042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693444.1">
        <property type="nucleotide sequence ID" value="XM_007695254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLF6"/>
    <dbReference type="GeneID" id="19124083"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41569"/>
    <dbReference type="eggNOG" id="ENOG502QQSB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031217_0_0_1"/>
    <dbReference type="OrthoDB" id="2099887at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004885979" evidence="1">
        <location>
            <begin position="17"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="472" mass="51614" checksum="AB5BDD188CC65705" modified="2014-04-16" version="1">MFLRTALLSLTALAAAKEMPKDEFRAAQLYDSGIRHENNMALKKESWAKQEAAGMYNSAQFAEVKNKVECINGTAITDTDVFKCKNIDLLHFLSHAELGSTRGVGSSSWGWTSDDGREFVAIGQQDGAAFAEINKEGKLVYLGRLPAYSTPSTWREIRGQNNLMIIGSEAQGHGIQIFDMKKLLTVNPASPKLFSNSADLTGHFKGLPSGRAHNVVTNPETNFIYAVGAQPRTDKCKSGIIFIDITDPSNPTTPGCASQDGYVHDAQCLIYHGPDTQFEGHEICYGYNEDSLSIYDVTNKKAPVLLSVTSYEGAAYTHQGAVLDPKNQKYLLLDDEYDEYDKVGPGVPGNPITYIWDISSLRAPKQTGLYRSGAKGVDHNQYVANGFAYQSNYGTGFRVLDVRSIPQDPTGAGVREVGFFDIYPEDDNLPGGGSVDFVGTWSSYALFKSGHILVNTMERGAFVVKLQAGFDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLW4</accession>
    <name>W6YLW4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_42757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964189">
        <property type="protein sequence ID" value="EUC40187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693303.1">
        <property type="nucleotide sequence ID" value="XM_007695113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLW4"/>
    <dbReference type="GeneID" id="19124189"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_42757"/>
    <dbReference type="eggNOG" id="ENOG502SEDQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176406_0_0_1"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8356" checksum="47014B40FF63ED72" modified="2014-04-16" version="1" fragment="single">MSLTNLPRELLYAIAEHLHAESDLNAFARANRLLYHLTNPYLYDHNIRHSNSTALLWAAEHGKERTLCKLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNJ2</accession>
    <name>W6YNJ2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_30232</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="KI964131">
        <property type="protein sequence ID" value="EUC40922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692567.1">
        <property type="nucleotide sequence ID" value="XM_007694377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNJ2"/>
    <dbReference type="STRING" id="930090.W6YNJ2"/>
    <dbReference type="GeneID" id="19121642"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30232"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_4_2_1"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000002">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="7"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="171" mass="18301" checksum="2EF00456EB4584A1" modified="2014-04-16" version="1">MSNPRVFFDVSIGGQPAGRIVMELFADQVPKTAENFRALCTGEKGTGKSGKPLHYQGSVFHRVIPQFMLQGGDFTRGNGTGGESIYGDKFEDENFKLSHTGPGILSMANAGPGTNGSQFFICTVKTSWLDGKHVVFGKVVEGLDVVQAVEKVGSQTGKTSKEVKIEKSGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YP92</accession>
    <name>W6YP92_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_31323</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964380">
        <property type="protein sequence ID" value="EUC39500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693981.1">
        <property type="nucleotide sequence ID" value="XM_007695791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YP92"/>
    <dbReference type="GeneID" id="19121842"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31323"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF21">
        <property type="entry name" value="GENERAL AMINO ACID PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="46"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC39500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="524" mass="56391" checksum="1651E5FE00583DE1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPZ5</accession>
    <name>W6YPZ5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_111146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964318">
        <property type="protein sequence ID" value="EUC39588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693890.1">
        <property type="nucleotide sequence ID" value="XM_007695700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPZ5"/>
    <dbReference type="STRING" id="930090.W6YPZ5"/>
    <dbReference type="GeneID" id="19119721"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111146"/>
    <dbReference type="HOGENOM" id="CLU_191091_0_0_1"/>
    <dbReference type="OrthoDB" id="10341284at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="87" mass="10016" checksum="CE7E928426EEEBB8" modified="2014-04-16" version="1" fragment="single">EWILLVLVYAVIAMRIYMRQSRFRKNLDIAGYLLIVFALNALALTTWDTIVYNTGALNGKVRSKLLSKVGFDISICFFLWICAFFTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR24</accession>
    <name>W6YR24_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_29390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691571.1">
        <property type="nucleotide sequence ID" value="XM_007693381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR24"/>
    <dbReference type="STRING" id="930090.W6YR24"/>
    <dbReference type="GeneID" id="19121496"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29390"/>
    <dbReference type="eggNOG" id="ENOG502SC4V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_138_0_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="21"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="207" mass="23424" checksum="4BBE0AEF4760052B" modified="2014-04-16" version="1">MRLLNTETLELTSFVGQVLDYVILSHQWEEEEVVFEDVSKVPLSRQTNRARAKRGFAKVLGTCALAVKDGFKWVWIDSCCIDKSSSSGLQESINSMFQSYQRAQICYAYLSNVADISSGWGEAFSRSLWFTRGWTLQGLLAPCTVEFYSADWRPIGTKFCRSKQVASITGIEVAVLESDWVTAEDKLSAAQKLSWAAHRHVYKVEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR99</accession>
    <name>W6YR99_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_30956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964206">
        <property type="protein sequence ID" value="EUC40033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693452.1">
        <property type="nucleotide sequence ID" value="XM_007695262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR99"/>
    <dbReference type="GeneID" id="19121778"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30956"/>
    <dbReference type="eggNOG" id="ENOG502SIYP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014331_1_0_1"/>
    <dbReference type="OrthoDB" id="5411773at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="595" mass="65666" checksum="28E198DBF1869094" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRH8</accession>
    <name>W6YRH8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964185">
        <property type="protein sequence ID" value="EUC40225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693265.1">
        <property type="nucleotide sequence ID" value="XM_007695075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRH8"/>
    <dbReference type="GeneID" id="19121748"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30811"/>
    <dbReference type="eggNOG" id="ENOG502RPKS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059751_0_0_1"/>
    <dbReference type="OrthoDB" id="3798784at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="389" mass="43915" checksum="C3F64931E1C224F9" modified="2014-04-16" version="1">MTNTNLTIAAVFASLFGLALIFIALWCLSHYIHRCCLDIGQWLHALSPHSDKDPPVVYVEKRRSRSRKSERGRRLDPLRAKRDHESGNFEYERTGDRGIEMRPTVQLCAPVQAQQQPYNPTYCPSLGWQDQTQNMQSVMQHRTPMYWQAQGVPRVPIYVMQTAIPQQSNRQTAMEISEPLQGPPRQQPHMLSQPEKCLSAKSRSPEKYARKPRKVDYIHICDEYPPFVLEALNKAALSSSSSSTSSDGSETTQEVPRTTIPCAPPACIKTKQYPDIVARGRDTPRTYPRQCVGRNGRGNGPDSQVRRLPSVPGVWIAQRTSRAVGMVGVHGRGEGDEKRAKESKRKANKDTDEEQEMKQAVEGFLASGLCNRRTRCPNRNQDRAVCSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRW4</accession>
    <name>W6YRW4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_9860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964184">
        <property type="protein sequence ID" value="EUC40228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693250.1">
        <property type="nucleotide sequence ID" value="XM_007695060.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6YRW4"/>
    <dbReference type="GeneID" id="19129296"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9860"/>
    <dbReference type="eggNOG" id="ENOG502QQWJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003023_0_0_1"/>
    <dbReference type="OrthoDB" id="2015333at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04043">
        <property type="entry name" value="C2_Munc13_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
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    </dbReference>
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        </location>
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        </location>
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        </location>
    </feature>
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            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC40228.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1366" mass="156919" checksum="4D06956E5FEB2A51" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6YRW7</accession>
    <name>W6YRW7_COCMI</name>
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        <submittedName>
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        <name evidence="1" type="ORF">COCMIDRAFT_41274</name>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
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            <dbReference type="EMBL" id="EUC40375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="195" mass="21510" checksum="5095157CE03F3E15" modified="2014-04-16" version="1">MTKTIEDAYSNYSLVEESSNNALKERIIQKARYLLPQYMEPVPLDFAVHNYESLMRTSYDAGTGIGLTNVVLQAFTDAKKSLRGGIDSKIDIVVVKGTVLQAHVDLLLEANIGVHNTIHASKKRKRLQSLDSRGICFAILPNTGDGSTWRRLSYRSNSNTSICNCVDLPTGISPHIVTGESVRRMLLGSVDLTAR</sequence>
</entry>
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    <name>W6YSJ5_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein</fullName>
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    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_9566</name>
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        <dbReference type="NCBI Taxonomy" id="930090"/>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="OrthoDB" id="416441at2759"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0008239">
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="592"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="599" mass="68098" checksum="D5595C361175282D" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6YT22</accession>
    <name>W6YT22_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_30428</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964147">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT22"/>
    <dbReference type="GeneID" id="19121675"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30428"/>
    <dbReference type="HOGENOM" id="CLU_1137822_0_0_1"/>
    <dbReference type="OrthoDB" id="3680145at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="244" mass="27647" checksum="C902CCFCF796B5BE" modified="2014-04-16" version="1">MESLPPAWIKRDPQRGEVLTHSGTSSAPSTSISNTLHHPETTTGSVYQRSHTLKIGRSKKSTSDPQILQFPHTRTLPTPTRFSDYMETMKSESEQHGPTVLPSARQVFRKRREYLLVQALKDSIINFSRTNLALRTSIAEEVKKGIEGNLTGIEKDPIQIVTTVGSHGKTFWSRVHQECYHSHAVLRSQPLHQIYSKKDIERILFFWAVHQSTLSYGDIACKLHLPVGALLSWILGFIDRPQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTP9</accession>
    <name>W6YTP9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1774-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_107407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OrthoDB" id="3342455at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <dbReference type="InterPro" id="IPR013920">
        <property type="entry name" value="DUF1774_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37992:SF1">
        <property type="entry name" value="DUF1774-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37992">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08611">
        <property type="entry name" value="DUF1774"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0472">Membrane</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
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    <name>W6YUL8_COCMI</name>
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        </recommendedName>
    </protein>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cytochrome P450 family.</text>
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        <property type="protein sequence ID" value="EUC41238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="930090.W6YUL8"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome P450"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
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        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC41238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="59330" checksum="35912EB26DD4652C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUW2</accession>
    <name>W6YUW2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein BTN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_38825</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the battenin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6YUW2"/>
    <dbReference type="GeneID" id="19123560"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38825"/>
    <dbReference type="eggNOG" id="KOG3880">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="5965864at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903826">
        <property type="term" value="P:L-arginine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015819">
        <property type="term" value="P:lysine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003492">
        <property type="entry name" value="Battenin_disease_Cln3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018460">
        <property type="entry name" value="Battenin_disease_Cln3_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981:SF0">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02487">
        <property type="entry name" value="CLN3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CLN3_BTN1"/>
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    </dbReference>
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        <property type="entry name" value="BATTENIN"/>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0926">Vacuole</keyword>
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        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="277"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
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            <begin position="219"/>
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        </location>
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            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007467"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU361113"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="449" mass="48771" checksum="67B4A25C662B44CC" modified="2014-04-16" version="1">MPGSPASSWALYRARLQHVFHGADPRVCAAFWLFGLINNVLYVIILSAALDLVGPNVPKGVVLLADVLPSFLTKLCAPYFIHKIPYHVRIVAFVALSAAGMLIIALTPPLQDSATIAIKMCGIMMASLSSGGGELSFLGLTHFYGHFALASWGSGTGGAGLIGAGAYAIATNTLGIDPRTSLLVFSFLPLVMIFSFFFVLPLGPLRAGTSKQAEYEAIDDEEADAEDEEATEAREHDDLLSSSMHSASGRTFSSANSKPASSALSSFQANLNRARGLFFPYMLPLLLVYIAEYTINQGVAPTLLFPLESSPFDEYRSFYSTYNAIYQVGVFISRSSTPFIRIHHLYLPSFLQVGNLILLTLHAMFAFIPSYYIVCIIIFWEGLLGGLVYVSTFAEITDNVPKEDREFSLGATSVSDSAGICIAGFLGMVVEVSLCRWQVEHGRNYCKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV05</accession>
    <name>W6YV05_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="2" type="ORF">COCMIDRAFT_8886</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889436" description="Apple domain-containing protein" evidence="1">
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            <begin position="17"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="691" mass="73570" checksum="BBCE3107AEE3F0AB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW50</accession>
    <name>W6YW50_COCMI</name>
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        <recommendedName>
            <fullName evidence="3 9">Tethering factor for nuclear proteasome STS1</fullName>
        </recommendedName>
    </protein>
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        <name evidence="11" type="ORF">COCMIDRAFT_8571</name>
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    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Binds the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cut8/STS1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC41775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_8571"/>
    <dbReference type="eggNOG" id="ENOG502RNK4">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033658_0_0_1"/>
    <dbReference type="OrthoDB" id="10061064at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071630">
        <property type="term" value="P:nuclear protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031144">
        <property type="term" value="P:proteasome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1590:FF:000001">
        <property type="entry name" value="Tethering factor for nuclear proteasome STS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1590">
        <property type="entry name" value="Tethering factor for nuclear proteasome Cut8/Sts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013868">
        <property type="entry name" value="Cut8/Sts1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038422">
        <property type="entry name" value="Cut8/Sts1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032:SF1">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08559">
        <property type="entry name" value="Cut8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC41775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="311" mass="34201" checksum="10401704D618D4E2" modified="2014-04-16" version="1">MNVQYQAFTPPHLLNNNNRRSPTRNIMPSSTAMTGRKRKADDEGSAGDDDRMSASPSTSPAILPRPAPRGMKRMRTNVSGRPLPLPRLLETLSADEMRNLLQSICQRHPDIGNEVVTTAPRPSIQSAMEVLSKYEAAFQGAFPFGNRASSDYAYNRVRQQLDDLLDSLKDFTPHFLPPNEQQPATSLAFLDGATEILHRLPNWDTYQHNRHKQEAYEEMAKAWAIVIREAAKRAGGIQLQYGGWDQKIAKHNEVSGGKMQEAVNELRGGLGWMGAETGNATTAGPADAMSIRQQLLSGNYGSGSSASIGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW68</accession>
    <name>W6YW68_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">General negative regulator of transcription subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_100336</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964023">
        <property type="protein sequence ID" value="EUC43637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689848.1">
        <property type="nucleotide sequence ID" value="XM_007691658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW68"/>
    <dbReference type="STRING" id="930090.W6YW68"/>
    <dbReference type="GeneID" id="19117656"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100336"/>
    <dbReference type="eggNOG" id="KOG2150">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013819_3_0_1"/>
    <dbReference type="OrthoDB" id="293823at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.1020:FF:000006">
        <property type="entry name" value="CCR4-NOT transcription complex, subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012270">
        <property type="entry name" value="CCR4-NOT_su3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007207">
        <property type="entry name" value="Not_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04065">
        <property type="entry name" value="Not3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005290">
        <property type="entry name" value="NOT_su_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-Not complex component Not N-terminal" evidence="13">
        <location>
            <begin position="3"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="14">
        <location>
            <begin position="499"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="240"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="124"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="355"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC43637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="631" mass="70854" checksum="AF6C8D0AFADA301A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWR7</accession>
    <name>W6YWR7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosome subunit biogenesis protein NIP7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_8359</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with pre-ribosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NIP7 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964077">
        <property type="protein sequence ID" value="EUC41995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691473.1">
        <property type="nucleotide sequence ID" value="XM_007693283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWR7"/>
    <dbReference type="STRING" id="930090.W6YWR7"/>
    <dbReference type="GeneID" id="19126293"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8359"/>
    <dbReference type="eggNOG" id="KOG3492">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097217_0_0_1"/>
    <dbReference type="OrthoDB" id="27490at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd21146">
        <property type="entry name" value="Nip7_N_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21151">
        <property type="entry name" value="PUA_Nip7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.10:FF:000002">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.220:FF:000001">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040598">
        <property type="entry name" value="NIP7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055359">
        <property type="entry name" value="Nip7_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016686">
        <property type="entry name" value="Ribosomal_synth_fac_NIP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005155">
        <property type="entry name" value="UPF0113_PUA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17833">
        <property type="entry name" value="pre-PUA_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03657">
        <property type="entry name" value="UPF0113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017190">
        <property type="entry name" value="Rbsml_synth_fac_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88802">
        <property type="entry name" value="Pre-PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUA" evidence="8">
        <location>
            <begin position="98"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC41995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="185" mass="20407" checksum="E02973607AFBADA2" modified="2014-04-16" version="1">MRPLTEPETKTLFEKLASYCGKGITNLIADPAGGNDRNVFRVQGSRVYYVRESLANLATSVARDNLLSLGICLGKFTKTGKFRLHITALSVIAPHARYKVWVKQNGEMPFLYGGNVLKAHVGRWSEDCPEHQGVVVLSMNDTPLGFGVSARSTADARKLDPTGIVTFRQADIGEYLREEDSLFTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXF5</accession>
    <name>W6YXF5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coenzyme Q-binding protein COQ10 START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_104100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964069">
        <property type="protein sequence ID" value="EUC42218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691279.1">
        <property type="nucleotide sequence ID" value="XM_007693089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXF5"/>
    <dbReference type="STRING" id="930090.W6YXF5"/>
    <dbReference type="GeneID" id="19118441"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104100"/>
    <dbReference type="eggNOG" id="KOG3177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079653_1_1_1"/>
    <dbReference type="OrthoDB" id="292693at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="5">
        <location>
            <begin position="53"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="246" mass="27243" checksum="348378333E4C70FC" modified="2014-04-16" version="1">MPPLKLARPLLQPSSSHHHHLTTTQRRTFLPNPFSSLSPSPSTPQILTATRTLPYPPSPVYSIIADVPSYSSFLPYCAHSTVSKWSAPDRHYNRRWPSEGVITTGFGAITESFASRIYCVPGRWVESVGGEAETSLDAREVAHHFAQAGTEQRKGGTREGSNGLLTYLRSKWQVEPVREAHTRVSLVVEFSFANPMYAALSGGVAPKVAEYMVRAFETRVQEVLERNPEMVTASLGDMEGSAMRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXR0</accession>
    <name>W6YXR0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_103834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964065">
        <property type="protein sequence ID" value="EUC42338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691169.1">
        <property type="nucleotide sequence ID" value="XM_007692979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXR0"/>
    <dbReference type="GeneID" id="19118384"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103834"/>
    <dbReference type="eggNOG" id="ENOG502T9HV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_579982_0_0_1"/>
    <dbReference type="OrthoDB" id="3798749at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="436" mass="49470" checksum="E8B48C6EF725ACD3" modified="2014-04-16" version="1">MNVDLPVLLPFGFNEEYQSLFAEKYGVKKQHEPLHFHVMSLREISALQRLRARKLALPAASVTDSALNKHRRIRKPKKIKMSRNSDREKRSHSVAIPKPPVSPSRAPKNPLRSMRDTKRNLETDTDRRLGASCEIPIILDDNSAQSGTPGKLNPRMRDARASPKLILRDISPTHDLRDTTFTKLPGDRYGTTNSGEKDMRLVDIDDFEMRKKVAQLMAVAPALPVRDLYYLIIDSEGRLSKAKKKAIRMSEAPDTLRTSTQLSLQPQTLVNKSDIEGAIVNNSNSDTQKTMIKIDLSDPIFKWDEDEPVPEPPPTAKPGRSKSATKNKQTQSAHSHHSAKESKRKTPATQTPSSQSKKCPKVSHSKPTSIRETSSDRDFIVADGVVHYVSDFDDSDDFFLSRNVIIPSRTRRQRRKFSMIREAMKLYIRWQLDSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY06</accession>
    <name>W6YY06_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Stress activated MAP kinase interacting protein Sin1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_7943</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964060">
        <property type="protein sequence ID" value="EUC42458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690996.1">
        <property type="nucleotide sequence ID" value="XM_007692806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY06"/>
    <dbReference type="STRING" id="930090.W6YY06"/>
    <dbReference type="GeneID" id="19125473"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7943"/>
    <dbReference type="eggNOG" id="KOG3739">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005130_0_0_1"/>
    <dbReference type="OrthoDB" id="241990at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038203">
        <property type="term" value="P:TORC2 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000263">
        <property type="entry name" value="Stress activated MAP kinase interacting protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031567">
        <property type="entry name" value="CRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008828">
        <property type="entry name" value="Sin1/Avo1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031313">
        <property type="entry name" value="Sin1_PH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13335">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13335:SF1">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16978">
        <property type="entry name" value="CRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16979">
        <property type="entry name" value="SIN1_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRIM" evidence="3">
        <location>
            <begin position="348"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="SIN1-type PH" evidence="4">
        <location>
            <begin position="731"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="459"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="515"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="846" mass="92505" checksum="391FEE91AAA657E8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY97</accession>
    <name>W6YY97_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_103211</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964057">
        <property type="protein sequence ID" value="EUC42545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690928.1">
        <property type="nucleotide sequence ID" value="XM_007692738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY97"/>
    <dbReference type="GeneID" id="19118246"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103211"/>
    <dbReference type="eggNOG" id="ENOG502RJY5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012440_0_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="659"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="727"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="754"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="781" mass="89285" checksum="BA9F814C967880D4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYJ2</accession>
    <name>W6YYJ2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_9530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964150">
        <property type="protein sequence ID" value="EUC40629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692856.1">
        <property type="nucleotide sequence ID" value="XM_007694666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYJ2"/>
    <dbReference type="GeneID" id="19128630"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9530"/>
    <dbReference type="HOGENOM" id="CLU_713681_0_0_1"/>
    <dbReference type="OrthoDB" id="3797359at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="387" mass="44039" checksum="CE726BC0698E8FFB" modified="2014-04-16" version="1">MPPDPRDTMLSRLEPLDPNNYIMALSAGSDQFIGSPNGYKATYIPSDVLYPLFTGLVKRITWASLRCIPNSFFFELELIDGRFACRIGTHIPPALTDFLLNFMKSKTHLPYLRIRYGANDSFVAWSKKVWIYSKVPPQLIVRLQQISSYSNTKYNVTKGDGDVGWSFAAYSVSSAWYEMWADLEMDERASIIAEELAHVTISPYSEKGETFAFIKKTIPGIEPPFIVHFEGEQTYSNFTFDKNNTTAPPKRYPRLENLDDRDFRVAISKKKIRRRRTNDPWDLDLKKGEKLLVLRDMEPPGLTFWDDKVDQDPKAAYARFMEDLGNVPRRNASRKSKTSSCWGFVFTIYWYCSRVPVGFCTSGSRKAATSGIRIGSPGSASLKKPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZA8</accession>
    <name>W6YZA8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitin synthase</fullName>
            <ecNumber evidence="3">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_39046</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="3"/>
    <dbReference type="EMBL" id="KI964044">
        <property type="protein sequence ID" value="EUC42933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690530.1">
        <property type="nucleotide sequence ID" value="XM_007692340.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6YZA8"/>
    <dbReference type="GeneID" id="19123605"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39046"/>
    <dbReference type="eggNOG" id="KOG2571">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002273_0_0_1"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF38">
        <property type="entry name" value="CHITIN SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1437"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1480"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1511"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1555"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1679"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1711"/>
            <end position="1737"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="15">
        <location>
            <begin position="1"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="16">
        <location>
            <begin position="430"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="17">
        <location>
            <begin position="1020"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="698"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="740"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="818"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="747"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="849"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="920"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="940"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="969"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC42933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1813" mass="204011" checksum="59E1CE6393874740" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z022</accession>
    <name>W6Z022_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LicD/FKTN/FKRP nucleotidyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_28338</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EUC43195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009100">
        <property type="term" value="P:glycoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009644">
        <property type="entry name" value="FKTN/MNN4/W02B3.4-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007074">
        <property type="entry name" value="LicD/FKTN/FKRP_NTP_transf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407">
        <property type="entry name" value="FUKUTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407:SF28">
        <property type="entry name" value="RIBITOL-5-PHOSPHATE TRANSFERASE FKTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04991">
        <property type="entry name" value="LicD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
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    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886295" description="LicD/FKTN/FKRP nucleotidyltransferase domain-containing protein" evidence="6">
        <location>
            <begin position="22"/>
            <end position="301"/>
        </location>
    </feature>
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        <location>
            <begin position="94"/>
            <end position="199"/>
        </location>
    </feature>
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        <location>
            <begin position="210"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="275"/>
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        </location>
    </feature>
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            <begin position="281"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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        </source>
    </evidence>
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            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="301" mass="35062" checksum="74A8900AFF807B93" modified="2014-04-16" version="1">MRLRTCAASVATASLFISSIAIPTPENTPLVQNSLTGQIKSREDRKPSTKYFHEPGGSLTLGHYDERYFNGVVSDDERTDTQKHMIRAYLNFFRENDLDTWIAHGTLLGWWWNGKRLPWDFDLDTQVADGTLQHIGRVHNQTKYPYVSYDGTVQREYLLDVNPWIWERERGDGANIIDARWIDTRNGLFIDITGLSETHPKERPGEWVCKNYHRYQTSDLYPMRETMFEGVVAKVPYNYDKILVDEYQEKALVVTEFNGHRWDPAIREWIKSQEVVDQEEAERKKQAEEAAKKAEEEAKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z028</accession>
    <name>W6Z028_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_5741</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC44982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688461.1">
        <property type="nucleotide sequence ID" value="XM_007690271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z028"/>
    <dbReference type="GeneID" id="19124722"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5741"/>
    <dbReference type="eggNOG" id="KOG1437">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031281_2_3_1"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.180.10:FF:000032">
        <property type="entry name" value="Fasciclin domain-containing protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886999" description="FAS1 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="20"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="167"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="386" mass="38396" checksum="AA2CF909FAEB1F48" modified="2014-04-16" version="1">MLKQLSVAAALAGAALAQNTPSLADALRSSSELSTLAGLVPQDVLQTLSSASNITILAPGNSAFEKVSPQLLSSLTTTPGAITALLQYHVLNGSYPSSAIPEQGAFVPTLLTNSSYTNVTGGQVVHATTEDNKVVFFTGSLSNSTVTTANVNFTGGVIHIIDTLLTIPGSVSDIATAAGLTSVRGALVSANLVETVNTTPDVTIFAPTNQAFQNIGSALPGLSADDLTKILTYHVIAGTVGYSTRLANGTSLATVNGANVTITINDNGIFVNNAEVVIADVLVANGVVHVIDQVLNPNNATVSNEDDGVPAYSGATPVSAAPFTSGQPTPSAPIGGGAGAGNGTRPTGSGSPTSSTGLPQATTNAAPVLAVSGGFAGLLAAAAFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0R6</accession>
    <name>W6Z0R6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_100591</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI964026">
        <property type="protein sequence ID" value="EUC43550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689960.1">
        <property type="nucleotide sequence ID" value="XM_007691770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0R6"/>
    <dbReference type="STRING" id="930090.W6Z0R6"/>
    <dbReference type="GeneID" id="19117705"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100591"/>
    <dbReference type="eggNOG" id="KOG0747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_14_1"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000304">
        <property type="entry name" value="UDP-glucose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="5">
        <location>
            <begin position="62"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC43550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="428" mass="48357" checksum="17D410657125D908" modified="2014-04-16" version="1">MSALEISSEVCDVPNGTHGTKRRRSSTVLNPRSYVKEKLWTQAPVFTGSTNFEPLPDAKNILITGGAGFIACWFVRHLVLTYPHYNVVSLDRLDYCATLNNTRILDGRPNFTFEQGDITSPATVKRVLRRHKIDTIVHFAAQSHVDLSFGNSYEFTHTNVYGTHVLLERAREHGVNKFIHISTDEVYGDVPIGAADLGEASILAPTNPYSASKAAAEMMVSAYRSSFKLPLITVRANNVYGPHQFPEKIIPKFIMLLQRKRKLLLHGDGSPTRRYLYAGDIVDALDTILHKGDIGQIYNIASKDEISNTEICYRLLDNFGIPRDTKSELIQWIQYTEDRPFNDQRYATDGSKLAALGWQPKTSFDEGLRITVDWYRRFGEVWWGDISRVLTSFPVVTGNEIRTKEEHEELPSSDGEGMHEEDSAVWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z131</accession>
    <name>W6Z131_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_7157</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="KI964030">
        <property type="protein sequence ID" value="EUC43398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690065.1">
        <property type="nucleotide sequence ID" value="XM_007691875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z131"/>
    <dbReference type="SMR" id="W6Z131"/>
    <dbReference type="STRING" id="930090.W6Z131"/>
    <dbReference type="GeneID" id="19125195"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7157"/>
    <dbReference type="eggNOG" id="ENOG502QRG8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004624_4_0_1"/>
    <dbReference type="OrthoDB" id="62120at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000033">
        <property type="entry name" value="Glucan 1,3-beta-glucosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="18">
        <location>
            <begin position="477"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="149"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="328"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="149"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="208"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC43398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="854" mass="97344" checksum="73C006042DA93A2E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1F8</accession>
    <name>W6Z1F8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoplasmic reticulum lectin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Protein OS-9 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_7041</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
            <orientation evidence="1 7">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the OS-9 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964026">
        <property type="protein sequence ID" value="EUC43543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689936.1">
        <property type="nucleotide sequence ID" value="XM_007691746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1F8"/>
    <dbReference type="STRING" id="930090.W6Z1F8"/>
    <dbReference type="GeneID" id="19125160"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7041"/>
    <dbReference type="eggNOG" id="KOG3394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025069_0_0_1"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045149">
        <property type="entry name" value="OS-9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012913">
        <property type="entry name" value="OS9-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414:SF0">
        <property type="entry name" value="ENDOPLASMIC RETICULUM LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414">
        <property type="entry name" value="OS-9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07915">
        <property type="entry name" value="PRKCSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0430">Lectin</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889610" description="Endoplasmic reticulum lectin" evidence="9">
        <location>
            <begin position="17"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="10">
        <location>
            <begin position="148"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="205"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="475"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC43543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="534" mass="59228" checksum="A63BACA3B3CF22B7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1P6</accession>
    <name>W6Z1P6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ER membrane protein complex subunit 7 beta-sandwich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_99639</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964017">
        <property type="protein sequence ID" value="EUC43880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1P6"/>
    <dbReference type="STRING" id="930090.W6Z1P6"/>
    <dbReference type="GeneID" id="19129504"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99639"/>
    <dbReference type="eggNOG" id="KOG3306">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073620_0_0_1"/>
    <dbReference type="OrthoDB" id="27095at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019008">
        <property type="entry name" value="Beta_sandwich_EMC7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039163">
        <property type="entry name" value="EMC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605:SF4">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09430">
        <property type="entry name" value="EMC7_beta-sandw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886526" description="ER membrane protein complex subunit 7 beta-sandwich domain-containing protein" evidence="7">
        <location>
            <begin position="18"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 7 beta-sandwich" evidence="8">
        <location>
            <begin position="31"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="240" mass="26109" checksum="B10BF31E2C6C851C" modified="2014-04-16" version="1">MKTAFAALSSFATLTSAARLLLQIPNTPLVNPSTLSSTTHATLQSSGPPIDAYLTRANTFNFNNVSVGSYLATVHCRDYAFEPLRIDVTLEEAVEGSGDKKEVIRAWQTFLGNEWDNKGESRGEGGNGLVIEARPVVPKYFYQERQGFSPLSFLKNPMILMAIVSMGLIFGMPKLMENMDPEMKEEFEQMQKNGVLGSGSTNTAQQIQNFDLASWMAGKTDAGTTSANANAPSPGQAKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z231</accession>
    <name>W6Z231_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_99294</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964013">
        <property type="protein sequence ID" value="EUC44050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689460.1">
        <property type="nucleotide sequence ID" value="XM_007691270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z231"/>
    <dbReference type="STRING" id="930090.W6Z231"/>
    <dbReference type="GeneID" id="19129441"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99294"/>
    <dbReference type="eggNOG" id="KOG2069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025395_1_0_1"/>
    <dbReference type="OrthoDB" id="1661054at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007255">
        <property type="entry name" value="COG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04124">
        <property type="entry name" value="Dor1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="482" mass="52230" checksum="AF6604CC1FD65280" modified="2014-04-16" version="1">MVDALYDLLVPYLDARPVPNDAATNAYLSRLTTLPLPALTSSEQQSLAQSSQSILRSIQALSKKSHKPIIASADHLLHLRTTLPHIGHDASTVHAELPALETAAQHFSDKYSRGADNAILDRRRKAMLLSRNIDRVSDVLDLPTLLSSAITSSTAAAQATSSTAIANANYASALDLHAHVKRLHTLYPNSPLISSLTAQAEQEMKTMTTNLITALQAQGIKLAGAMRTIGWLRRVAPELDESWSTKQAAIGSGEGTLGALFLVCRLVCLESMLEALSPLRDLADQETSKRTSKTTKVTENGWAAGQQTEKYLKKYLEVFREQSFAIISMYKSIFPSALPAPGSEDAAAPAVKPVDSSDPLQPIPSALATFPLHLVEMLFDTLRDYLPNVQDRSARDSLLTQVLYCAGSLGRLGADFSVMIALLEEDLRAELDESVEDSEADEEWVDVMKKHRVQASRLELLASGVGTARTASPVDRVASPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2W3</accession>
    <name>W6Z2W3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_37911</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689233.1">
        <property type="nucleotide sequence ID" value="XM_007691043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2W3"/>
    <dbReference type="STRING" id="930090.W6Z2W3"/>
    <dbReference type="GeneID" id="19123350"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37911"/>
    <dbReference type="eggNOG" id="KOG3822">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3857">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012323_0_0_1"/>
    <dbReference type="OrthoDB" id="1933379at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008260">
        <property type="term" value="F:succinyl-CoA:3-oxo-acid CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08192">
        <property type="entry name" value="MAR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.10">
        <property type="entry name" value="Glutaconate Coenzyme A-transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012792">
        <property type="entry name" value="3-oxoacid_CoA-transf_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02429">
        <property type="entry name" value="pcaI_scoA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="KETOACID-COENZYME A TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707:SF58">
        <property type="entry name" value="SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="3">
        <location>
            <begin position="28"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="191"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="937" mass="100876" checksum="81955277433E9DB0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3F3</accession>
    <name>W6Z3F3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_98095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689003.1">
        <property type="nucleotide sequence ID" value="XM_007690813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3F3"/>
    <dbReference type="GeneID" id="19129185"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98095"/>
    <dbReference type="HOGENOM" id="CLU_1731130_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="151" mass="15939" checksum="0503AC7F34F932C2" modified="2014-04-16" version="1">MDFTSPLNIPLQTMPSRTPYLSLTFSPCPASTPTVPSLPPYTSTCTSKTITSLPPAYTGQDANTSSRTPTAPQPPPPPPPASSAGEAQVQAPKPTTHSAAISPRDLEAATGMRGVAMPGETRRKIMCFAVYVVFGLAWMGALWVVVKLLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3R3</accession>
    <name>W6Z3R3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">KRR1 small subunit processome component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">KRR-R motif-containing protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ribosomal RNA assembly protein KRR1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_37590</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KRR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688884.1">
        <property type="nucleotide sequence ID" value="XM_007690694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3R3"/>
    <dbReference type="STRING" id="930090.W6Z3R3"/>
    <dbReference type="GeneID" id="19123278"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37590"/>
    <dbReference type="eggNOG" id="KOG2874">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040185_3_0_1"/>
    <dbReference type="OrthoDB" id="441223at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00024668"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00025908"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00032023"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00032993"/>
        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="517" mass="59053" checksum="4479CC5955B7FA2A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4C1</accession>
    <name>W6Z4C1_COCMI</name>
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        <recommendedName>
            <fullName evidence="11">Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_97272</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="9">Multi-pass membrane protein</topology>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="395"/>
        </location>
    </feature>
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        <location>
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            <end position="417"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC44780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="584" mass="64346" checksum="8740697E2C803E0F" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6Z4D7</accession>
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        <recommendedName>
            <fullName evidence="2">Mmc1 C-terminal domain-containing protein</fullName>
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    </protein>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963997">
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    <dbReference type="OrthoDB" id="5319015at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <dbReference type="InterPro" id="IPR056196">
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    <dbReference type="PANTHER" id="PTHR38644">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38644:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23868">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23867">
        <property type="entry name" value="Mmc1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="374"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="643" mass="70090" checksum="A4B7E64E2DC8E8BD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4D9</accession>
    <name>W6Z4D9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lytic polysaccharide monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6124</name>
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    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688872.1">
        <property type="nucleotide sequence ID" value="XM_007690682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4D9"/>
    <dbReference type="GeneID" id="19124848"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6124"/>
    <dbReference type="eggNOG" id="ENOG502SJFI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056960_1_0_1"/>
    <dbReference type="OrthoDB" id="3937708at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887151" description="Lytic polysaccharide monooxygenase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="43778" checksum="159DD22E20323302" modified="2014-04-16" version="1">MYSRSILLTLAAASVPLVSSQGDTSEGICYSYGVDFVDEGQYFIDSQSTEAFSAVSYFQGCNEDKADVLLVAPEGTPGETEFLCDQILTTPANENKLSTCPIKKNQMNSGHWLLLVLGNNGKGGQPFAWQRDLYLTVGPQVTTTYTPTVTMSVITTPTITQTVITTSTDTITVGPFSTVTMPSGTAKKIKTITPKPVTTTSTKTMTRTKVSTTKQFVYTTKTVTPTCTSKPHTGKPDKPCEYSPTKIHPAALVTPTVIPQARRWAPRADRVADVEWVRARIEAAKQKREAAKNLNRRAPDAPTTTVTFQTPVSTTVTQTAAAITTTETVLQSTEVTSTIPPPTVLSGILTKTTTLPTPTKTKVNFSFTTTTTTKTYGATFTRTTTAPPAPSVTECKKHGGQYWWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4F5</accession>
    <name>W6Z4F5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translocation protein SEC62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_37540</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC62 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688834.1">
        <property type="nucleotide sequence ID" value="XM_007690644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4F5"/>
    <dbReference type="STRING" id="930090.W6Z4F5"/>
    <dbReference type="GeneID" id="19123268"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37540"/>
    <dbReference type="eggNOG" id="KOG2927">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040936_0_0_1"/>
    <dbReference type="OrthoDB" id="200187at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004728">
        <property type="entry name" value="Sec62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011553">
        <property type="entry name" value="Sec62_asco"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00869">
        <property type="entry name" value="sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443:SF9">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03839">
        <property type="entry name" value="Sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="262"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="346"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC44633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="420" mass="46874" checksum="7ADECC9FA8D87D6C" modified="2014-04-16" version="1">MAEQEQPPPEYETHQGPPPPGSIAIPIPLGPNGEKPTPEQIQQIQMQIAAEAQRHGISIQEYVQRMRQQAMAQQQMQMQAQMEAQQRAQQQQQQQQPIQPGPPKPEAIALANWLKSQDLKPRTVVHDEKRKDMFRVKRAIRAIQSPAYQKARAKNPLLPEVYDRVTAENCFKLLPLSLLALRVSKADEDEHEGHNHAKPKRIKGLWTVKIEQHQDANDDSYYIWLYEGSQWKQKLYALGALVAVIAIVLFPLWPLMLRQGVWYLSMGMLGLIGLFFVMAIVRLILFIITIFVAPPGLWLYPNLFEDVGFFDSFRPVWAWQETPEDIKAKKAAKKEKKAAKLAAKAAGIKGKKHGHDHSRTTTPVPPNAAPFAAPPAPAPAPAPASAPVDHAPQATGADTTADGGATQRPPRATVEEVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4G5</accession>
    <name>W6Z4G5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_4292</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686809.1">
        <property type="nucleotide sequence ID" value="XM_007688619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4G5"/>
    <dbReference type="STRING" id="930090.W6Z4G5"/>
    <dbReference type="GeneID" id="19124191"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4292"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062843_0_0_1"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="369" mass="42451" checksum="1BAA41991AE04BAB" modified="2014-04-16" version="1">MEQRVPTYTSSPYQYIENYSEPYEAQTRNTNEPITGSFNERPSFHNFDHDTLVHRPMGTPMEFMDILALEVSCGSPHSTSSTISHSESVSSPPYTGFSAYNTLEPAFHNVQHSSTNHAAVSNEPESLWPSTYPEVTSWNSRPYVLPYHEIPSYEQRSYQLMPTILPEPRVSAPVPYLPYPMPQQDSPTPAVDSGAFDLSGFNNIGDESDDLSDSDSDDSWHDEPSSSRRPRRWSSRRAQPRSNVYRLEGWSANTCTFHTTTDRRHQCLELIGPNKDTPCPKKFQRPEHLRRHIRSVHGIGLVNVYKCKVPDCFARFRRSDNFRSHYLTHLRVGKRKGNNRKMTYQELKGILGPKEKDLVRWIKNKLTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4N1</accession>
    <name>W6Z4N1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_26796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688521.1">
        <property type="nucleotide sequence ID" value="XM_007690331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4N1"/>
    <dbReference type="STRING" id="930090.W6Z4N1"/>
    <dbReference type="GeneID" id="19121002"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26796"/>
    <dbReference type="eggNOG" id="KOG1243">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010392_1_2_1"/>
    <dbReference type="OrthoDB" id="447103at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF3">
        <property type="entry name" value="N-TERMINAL KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="712"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="769"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="779" mass="84446" checksum="1924973064740620" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4R6</accession>
    <name>W6Z4R6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrodipicolinate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_26975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688718.1">
        <property type="nucleotide sequence ID" value="XM_007690528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4R6"/>
    <dbReference type="STRING" id="930090.W6Z4R6"/>
    <dbReference type="GeneID" id="19121031"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26975"/>
    <dbReference type="eggNOG" id="ENOG502RBA9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_4_1_1"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF38">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHETASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G00110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="34985" checksum="3964553FF1CF0295" modified="2014-04-16" version="1">MGSMPEVKKAPQIDLAGLVPAPVTPFNRDGSVDYAAIQRLGSWLGSIPGVKGLVVLGHAGEGTFLTQEEQVEVIKAFVKSVDDKIPIIAGITTEGTEVAALEAQRAKAAGAKAGLLYPSHGWLRFGYQPGAPQDRYKTVYEKSGLPLILFQYPDNTKATYNLDTLLEIAAQPGVIAMKNGVRNMRRWDVEIPIIKKQNPDLTILTCHDEYLLHTCFDVDGMLVGYGNIAPEPLLEMIEAGKARDYPRARAIHDRLLPVTRNVYHRGSHMEGTVALKHGLVARGILEHATVRSGLLPLQDGAEQEIHAAFKSASLGKVSAPKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4S4</accession>
    <name>W6Z4S4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alpha-actinin-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_7837</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-actinin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964055">
        <property type="protein sequence ID" value="EUC42604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690857.1">
        <property type="nucleotide sequence ID" value="XM_007692667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4S4"/>
    <dbReference type="STRING" id="930090.W6Z4S4"/>
    <dbReference type="GeneID" id="19125407"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7837"/>
    <dbReference type="eggNOG" id="KOG0035">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005217_0_2_1"/>
    <dbReference type="OrthoDB" id="10017054at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21291">
        <property type="entry name" value="CH_SpAIN1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000138">
        <property type="entry name" value="Alpha-actinin, sarcomeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000097">
        <property type="entry name" value="Alpha-actinin, sarcomeric (F-actin cross linking protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000279">
        <property type="entry name" value="Calponin domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000223">
        <property type="entry name" value="Related to alpha-actinin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000030">
        <property type="entry name" value="Related to alpha-actinin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000077">
        <property type="entry name" value="Related to alpha-actinin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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            <end position="519"/>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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            <dbReference type="EMBL" id="EUC42604.1"/>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="640" mass="73527" checksum="6E02FC366F33763A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4X1</accession>
    <name>W6Z4X1_COCMI</name>
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        <submittedName>
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        </submittedName>
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        <name evidence="3" type="ORF">COCMIDRAFT_5928</name>
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            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
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    <name>W6Z5C5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_96345</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z5C5"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_96345"/>
    <dbReference type="eggNOG" id="ENOG502R8TT">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104718_0_0_1"/>
    <dbReference type="OrthoDB" id="6509908at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39605">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39605:SF1">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="163" mass="17964" checksum="13F322DD5EBA2DCB" modified="2014-04-16" version="1">MPSMNSTVFHAYAYGTAFWYGLRGLCRVYDPIMVIGWFRPPSQLNLAPNDLETYNVRNDGWCLITLALVLISLTNAVPFTAESAKKFSSVPYAKAIVAATIFHHVATGIGAYQHYKLPSHYNTSMGIGVWGNIWLSLTGLFTLALLQSDAGDMSVEQAAKKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6Q9</accession>
    <name>W6Z6Q9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_60433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963983">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6Q9"/>
    <dbReference type="STRING" id="930090.W6Z6Q9"/>
    <dbReference type="GeneID" id="19124810"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_60433"/>
    <dbReference type="eggNOG" id="ENOG502T1M3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_544649_0_0_1"/>
    <dbReference type="OrthoDB" id="3786931at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="501" mass="58060" checksum="758DF02EDEF4A589" modified="2014-04-16" version="1" fragment="single">MVSFLGRMETRRLHGTDMKRLVRILRDVPTPGEERYERKLALYRKFTKLDIQDLPRRLRSSPLLFGTSGNLCCIHKGLDAHLINDIWAWVKHEFEGATGQFLYPLIMCNLLTPDKEWRVRQMEPVLQMWRRDFKLDASAPPGREPIYCGDKWRYQRDQCPACIMARIASDEDVLSALFTGMVGRLSTKSLANPNPAPDTPYWEETSSKRVRFVKYWMRTTRGGERALYEAGDLGMRLKFLMLERRHQKESLYQTLSGTTATSFSDTSSNHKKGEHSVHMQIDTKLGPNPRPFSVEQFSPAEALGFDMREKHNYNSTQSYRQDTRSAYHQDTYPASPSKSSFYSSYHHQHSSTSLNPSDSISMTALHPAPLRIKKRDPTHGHHRNPSCISTTSTILSYNGGPSQHPYQRDPFTNPIYNMSEPAKPQQAELYQEKYRKLLVADNPFTQQPTTTFKPEQRDTGLPRPRQASMYFAYGDRRFNGGRFDGVDEEPRREELEMWDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6S1</accession>
    <name>W6Z6S1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_90159</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686133.1">
        <property type="nucleotide sequence ID" value="XM_007687943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6S1"/>
    <dbReference type="STRING" id="930090.W6Z6S1"/>
    <dbReference type="GeneID" id="19127624"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90159"/>
    <dbReference type="eggNOG" id="KOG3056">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011047_0_0_1"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000174">
        <property type="entry name" value="DNA replication licensing factor mcm10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040184">
        <property type="entry name" value="Mcm10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055065">
        <property type="entry name" value="OB_MCM10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015408">
        <property type="entry name" value="Znf_Mcm10/DnaG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454:SF11">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22379">
        <property type="entry name" value="OB_MCM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09329">
        <property type="entry name" value="zf-primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM10 OB-fold" evidence="10">
        <location>
            <begin position="332"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger Mcm10/DnaG-type" evidence="9">
        <location>
            <begin position="483"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="92"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="622"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="188"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="775" mass="85578" checksum="26DA6BF1E9E62246" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6U7</accession>
    <name>W6Z6U7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_94784</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687791.1">
        <property type="nucleotide sequence ID" value="XM_007689601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6U7"/>
    <dbReference type="GeneID" id="19128515"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94784"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF10">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="18"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="526" mass="58454" checksum="BC0FBE57E2537FFA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7G9</accession>
    <name>W6Z7G9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Cytochrome P450</fullName>
                <ecNumber evidence="14">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="14">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_110985</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14 15">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="14"/>
    <dbReference type="EC" id="1.6.2.4" evidence="14"/>
    <dbReference type="EMBL" id="KI964295">
        <property type="protein sequence ID" value="EUC39641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693841.1">
        <property type="nucleotide sequence ID" value="XM_007695651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7G9"/>
    <dbReference type="STRING" id="930090.W6Z7G9"/>
    <dbReference type="GeneID" id="19119697"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110985"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_7_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000040">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 14" id="KW-0288">FMN</keyword>
    <keyword evidence="4 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="12 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0521">NADP</keyword>
    <keyword evidence="11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="16">
        <location>
            <begin position="502"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="17">
        <location>
            <begin position="676"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC39641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1064" mass="118301" checksum="AD13E9F009EED9CF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z832</accession>
    <name>W6Z832_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Guanine nucleotide-binding protein subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_89020</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">G proteins are composed of 3 units, alpha, beta and gamma.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G protein gamma family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685615.1">
        <property type="nucleotide sequence ID" value="XM_007687425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z832"/>
    <dbReference type="STRING" id="930090.W6Z832"/>
    <dbReference type="GeneID" id="19127393"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89020"/>
    <dbReference type="eggNOG" id="ENOG502S5Z5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163540_1_1_1"/>
    <dbReference type="OrthoDB" id="19232at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
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    </dbReference>
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        <property type="term" value="F:G-protein beta-subunit binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GGL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041848">
        <property type="entry name" value="Ste18_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28189">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28189:SF1">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00631">
        <property type="entry name" value="G-gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="7" id="KW-0564">Palmitate</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="G protein gamma" evidence="11">
        <location>
            <begin position="29"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC47882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="100" mass="11394" checksum="C64E6BC3F1234761" modified="2014-04-16" version="1">MPATPTMMVAAPYEIRTGGDGKTKKQSMAELKLRRLTELNQRLREDLERRRIPVSEAALDLIAFTDKEPKDWMVPSRWGTIDKRDDPYAPQQSNGCCAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z884</accession>
    <name>W6Z884_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">[acyl-carrier-protein] S-malonyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_99897</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
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    <dbReference type="EMBL" id="KI964019">
        <property type="protein sequence ID" value="EUC43769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689693.1">
        <property type="nucleotide sequence ID" value="XM_007691503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z884"/>
    <dbReference type="STRING" id="930090.W6Z884"/>
    <dbReference type="GeneID" id="19129561"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99897"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2926">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_461495_0_0_1"/>
    <dbReference type="OrthoDB" id="541883at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.250">
        <property type="entry name" value="Malonyl-CoA ACP transacylase, ACP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050858">
        <property type="entry name" value="Mal-CoA-ACP_Trans/PKS_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42681">
        <property type="entry name" value="MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42681:SF1">
        <property type="entry name" value="MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="5">
        <location>
            <begin position="236"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC43769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="591" mass="64303" checksum="7462DCC3E38F23BB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8L5</accession>
    <name>W6Z8L5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7082 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_4607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963968">
        <property type="protein sequence ID" value="EUC46335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687150.1">
        <property type="nucleotide sequence ID" value="XM_007688960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8L5"/>
    <dbReference type="GeneID" id="19124304"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4607"/>
    <dbReference type="eggNOG" id="ENOG502QTDM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013895_0_1_1"/>
    <dbReference type="OrthoDB" id="1751210at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055509">
        <property type="entry name" value="DUF7082"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39463">
        <property type="entry name" value="MEDUSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39463:SF1">
        <property type="entry name" value="MEDUSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23305">
        <property type="entry name" value="DUF7082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7082" evidence="1">
        <location>
            <begin position="378"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="700" mass="76612" checksum="E0E0FAEFA58148E8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z981</accession>
    <name>W6Z981_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689347.1">
        <property type="nucleotide sequence ID" value="XM_007691157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z981"/>
    <dbReference type="STRING" id="930090.W6Z981"/>
    <dbReference type="GeneID" id="19124988"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6528"/>
    <dbReference type="HOGENOM" id="CLU_1992226_0_0_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="132" mass="15786" checksum="6239778532974387" modified="2014-04-16" version="1">MNDLPQELIDEICSHLPRDDLQDVLTLSRQFQYSAEKYSGFFEKYTLDTGNSAEFRSRFLSYRLLYLQEVIFRPTVPRFNWRGEDGEPVPYRETADEVRRRDESFTNQIQWLFHVFRSIEDQAGEMGIVGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9L5</accession>
    <name>W6Z9L5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_98853</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="4">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="4"/>
    <dbReference type="EMBL" id="KI964009">
        <property type="protein sequence ID" value="EUC44214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689291.1">
        <property type="nucleotide sequence ID" value="XM_007691101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9L5"/>
    <dbReference type="STRING" id="930090.W6Z9L5"/>
    <dbReference type="GeneID" id="19129344"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98853"/>
    <dbReference type="eggNOG" id="KOG2848">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_10_0_1"/>
    <dbReference type="OrthoDB" id="202234at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434:SF11">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="7">
        <location>
            <begin position="111"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="309" mass="34028" checksum="71B783B4094D1E9C" modified="2014-04-16" version="1">MSWLLYLAMPPVLIVAMRLLSLVLPAKPAQLLSYYAFAASSFILMGFCALYGTLVAIPLRLIGYGGLIQWSVGRAFKWCMWYGTGVTFRITGSMKKEGGVSGEDALKDRPAVFVGNHQTELDVLMLGCMFPKYTSVTAKKSLKYTPLLGWFMALSKTVFIDRANRTTARAAFDTAAQTMQSTRQSVFIFPEGTRSYASTPDLLPFKKGAFHLAVQAQVPIVPVVCANYSHVLNVKEQKFQPGVVDVTVLPPIQTKGLTAEHVDDLVKRTRDAMMEELIRLSHISGAGNGEPLPRSSGVDQSRGELRKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA52</accession>
    <name>W6ZA52_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_2498</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684797.1">
        <property type="nucleotide sequence ID" value="XM_007686607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA52"/>
    <dbReference type="STRING" id="930090.W6ZA52"/>
    <dbReference type="GeneID" id="19120676"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2498"/>
    <dbReference type="eggNOG" id="KOG0598">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_120_1_1"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11651">
        <property type="entry name" value="YPK1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000048">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
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            <end position="47"/>
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            <end position="103"/>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
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        <source>
            <dbReference type="EMBL" id="EUC48632.1"/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="Wang R."/>
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                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Schackwitz W."/>
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        <source>
            <dbReference type="Pfam" id="PF06985"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44444.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
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</entry>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
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    <dbReference type="HOGENOM" id="CLU_3092855_0_0_1"/>
    <dbReference type="OrthoDB" id="3670473at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="52" mass="5836" checksum="1F8C4EE8546CBAF4" modified="2014-04-16" version="1" fragment="single">GCLVLLQPRGQPKVWVVLQGSAPLAWKSVIQFTYRRILCATRQDAARLLTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBI8</accession>
    <name>W6ZBI8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase accessory subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_97211</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688708.1">
        <property type="nucleotide sequence ID" value="XM_007690518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBI8"/>
    <dbReference type="STRING" id="930090.W6ZBI8"/>
    <dbReference type="GeneID" id="19129012"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97211"/>
    <dbReference type="eggNOG" id="KOG3909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037350_1_0_1"/>
    <dbReference type="OrthoDB" id="27601at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03043">
        <property type="entry name" value="QTRT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028592">
        <property type="entry name" value="QTRTD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="6">
        <location>
            <begin position="31"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="500" mass="55327" checksum="C80C00886CD94322" modified="2014-04-16" version="1">MSVESPVQKLDQLPAEMLEFTLLKAAGSLAPRLGRLSVPGRNKILTPGFIGSTSRGIIPHISQDNFQKRVGLEGVYVPLEDFVEKHPQKTPPVLKYDVPEPLRSFIALPPETLLVLGARRNPPIPSPHANSNTEVGLLTSVGFTAVSSEFYAAATSKLQPDVVIGLADIPFGQESVSLKRKDRMSDRTETWLRDLVVKQSTVDNQGKGCAIFAPILPIERDLQSWYLEHLLDDMMDKISGVAIYDAYLLDDLPDQLHHLPRLSFHAPATPHELLRHISLGMDIFTVPFVNDATDAGIVLDFTFPAPRNESSDNTRRSLGIDMWGGHHAQSVTPLSDGCTCYACTKHHRAFLQHLLAAKEMLGWVLIQMHNHAILSAFFAGVRASIETGTFDTDVAAFESYYEPALPEKTGQGPRVRGYQFKSQSHAKKEKKNPKAFKKFSESDILKLKAAHGQQPNSNPETRDYIDDEALVGLVGIEHTTVDPDPLKQIDGLIIEDDKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCN6</accession>
    <name>W6ZCN6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_3347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685732.1">
        <property type="nucleotide sequence ID" value="XM_007687542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCN6"/>
    <dbReference type="GeneID" id="19122335"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3347"/>
    <dbReference type="HOGENOM" id="CLU_030741_0_0_1"/>
    <dbReference type="OrthoDB" id="3795190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="409" mass="44088" checksum="0B5570F448529365" modified="2014-04-16" version="1">MPKDAPQQSQPTPGAASPPKSPRSSCSPSKTAELWDGYERLAVEKAKERDELMHETHERNDCSTSRTSFDFRFKRAQTTIPSTTTPGCKSCGRPIIYASGMCEGCFKRTVVSPGNEEIVTTLGVAGHNMAVSGLCQIPSREEIITPTYASPKRASFCPLPGHLTDASTRTSSTQAGSVGRRKKSPSEPTQPSLQLQITPSTYTSRSQANSPPMTPTSPPSTAHSVSSMRRSSLANVTMLPKLRYPHSRNDSGTPSEFSTLYQTVSTTTTPPASLHRFGYPLQNTTSAWDDWDSDEGEEQGEEEERPGLSSWMGRRKIRSRNGGGAGGVGGGGGGAKTSMDQCDSAGEEARERMTMARKSRDERVEQTRVESVGGTSVRVERLVEPSRDGKVKKPSGFVRALSCGCGTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCQ1</accession>
    <name>W6ZCQ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_96240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963989">
        <property type="protein sequence ID" value="EUC45189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688311.1">
        <property type="nucleotide sequence ID" value="XM_007690121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCQ1"/>
    <dbReference type="GeneID" id="19128811"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96240"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_1_2_1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS multidrug transporter, putative"/>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF171">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
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        <property type="entry name" value="MFS general substrate transporter"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
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            <begin position="113"/>
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            <begin position="144"/>
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            <begin position="47"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="485" mass="53978" checksum="4D7D7A9CCD117D4D" modified="2014-04-16" version="1">MPIQDERAPLLQQSYSEEGQPCTHLRIEDLPSEENPREWTKGRKMANVAVIALMSILSPLVSSMFTPGIAQIAKDLNCSTTAVIGTTTGFVVMLGIGPLILAPLSETFGRRKIYLTCFSIFTLLQIPAALAPNIAFLITVRSIAGFFGSVAIANGGGTISDMFLPNERAGVFGWYLLGPLLGPTLGPLFGGLIVQRLGWRWVFWIMAIVCFINTLAGYFFLRETYAPAILSGKKAEFEAQTAEWDDTKYSYEGEDARPLREKIVQALKRPPKIFAQPIVAVMAVYQALIFGTTYSIYTNMQPIYEDDYRFSTEQVGLLYLGLGCGFLFAVWFLVPRIDTLYKSLTAKNHEKARPEFRLPLANIGSVFIPMSLFWFAWAVEKHMHWLVSIAATFFYGIGQVMIINSTQNYFIDSFEKYAASAIAAGTVFRSVFGGIIPILAPALFENLGYGWGISTFAFVTLFLAPAPILFYIFGERLRDRFPVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCU0</accession>
    <name>W6ZCU0_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_84203</name>
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    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007685733.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="70"/>
        </location>
    </feature>
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        </location>
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        </location>
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            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
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        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00184"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC49637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="269" mass="29812" checksum="89DDD7BA6A635209" modified="2014-04-16" version="1">MSGCVICKNPLKVEVERDEDEEYEGGASSSGKAPAPAPETVPDDVELSCGCHFHWDCLLSAYEITSCPNCSKEISVTEDNTQKVLCRLNNEGGVQENLDILPLLIEESYLKAYPEDRKARAFLEFCRAGDYKAIIELLLDDSSDDDDEDEQGDVEMSTTDDPNKETGIDRVLRYQDPIGDMQSGLHAAVHAQSREVAWLLLLLASNYPLLEFPPEVFQEAEAMGIMRGLTEDKVDIRSLKDAQGRTAEDIAKEIGGVWHGWTGNNRLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD72</accession>
    <name>W6ZD72_COCMI</name>
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        <recommendedName>
            <fullName evidence="21">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_34667</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD72"/>
    <dbReference type="STRING" id="930090.W6ZD72"/>
    <dbReference type="GeneID" id="19122610"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34667"/>
    <dbReference type="eggNOG" id="KOG1083">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_309269_0_0_1"/>
    <dbReference type="OrthoDB" id="422362at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AWS_dom"/>
    </dbReference>
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        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17907">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51215">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-0564">Palmitate</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="244"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="AWS" evidence="18">
        <location>
            <begin position="778"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="17">
        <location>
            <begin position="835"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="360"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="490"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wang R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685091.1">
        <property type="nucleotide sequence ID" value="XM_007686901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEM6"/>
    <dbReference type="GeneID" id="19127078"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87495"/>
    <dbReference type="eggNOG" id="ENOG502SQNJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1389994_0_0_1"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="43"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="187" mass="21788" checksum="73F3C8C4E1E73922" modified="2014-04-16" version="1">MAPIPTSTDDIRLRRMACPSKESVEKQLSIPETISPLDNYPPLLRIPSEIRREIFRYVLPSSNKRFILYTDCDSRSISRKWNKICRPHPDPHLTLDVLRTNRLIYHECLSVLYSENQFHFYAFNYLPVLDFIRHLSPEAKNQVRNVRLTPLTDKQDDPPASHDVFCTVIHDSLPGLSQLQADPVVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEN3</accession>
    <name>W6ZEN3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase family 81 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_87677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685175.1">
        <property type="nucleotide sequence ID" value="XM_007686985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEN3"/>
    <dbReference type="GeneID" id="19127112"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87677"/>
    <dbReference type="eggNOG" id="ENOG502RH0W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023528_0_0_1"/>
    <dbReference type="OrthoDB" id="2580323at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616:SF1">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889958" description="Glycoside hydrolase family 81 protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="553" mass="61619" checksum="F820D876514EF001" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFB8</accession>
    <name>W6ZFB8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_81301</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682878.1">
        <property type="nucleotide sequence ID" value="XM_007684688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFB8"/>
    <dbReference type="GeneID" id="19125844"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81301"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_573826_0_0_1"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="470" mass="53603" checksum="56D2AB2D4B4FE657" modified="2014-04-16" version="1">MATPGYNRYALFASADDNAATTRATPPDPSKNPFLNQVADDSIPWEKVKKRGAPVTASVSRPVAATKHRAKAASIQQLLNNGQSNNTPICTPEEKPHDPHENWCGVCCLKLPNKTALQNHIKQSPNHQNYCNLCKRVFKDRNGLKNHVDNSLGHETYCNLCLSAFKDQWGLKNHFENNYSVGHEFVCLTCLTGFKTSAELERHLQTAEKHTWCQTCRRRFRNQDERDEHWVKTLRHKHCLQPGCDFDGSDQASLTEHLRRDHFQCQGCKRILPSLTKLNQHYETCLFALSCPQCGEKCAGKSQLELHMTHCFRCEECDFHTSHKGNFDIHMTKHSSADLVCWGCDAPMRKYSSLINHLESGNCPKLGEATPLMRCLGMWWYSPLYMDLDLHAHIRTGRVDIHKVCEWMSEGGLHPFLCRDKDCGKTFSQLSSLLLHCESTACGWDVDRLNMPGLEKEFKQWCLRRDSGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFV2</accession>
    <name>W6ZFV2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_23288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684497.1">
        <property type="nucleotide sequence ID" value="XM_007686307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFV2"/>
    <dbReference type="GeneID" id="19120406"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23288"/>
    <dbReference type="HOGENOM" id="CLU_1331728_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="206" mass="22590" checksum="E7726CF11BBB70D8" modified="2014-04-16" version="1">MATDVFWRGGGARRYDLAVRRLVVVVVVAVVVVVVVVYRTAQRGSLSAGHETEQDDSTQHTAPSTQPTGRARWNTGQAEATTALRACKLDVTPMAWPAVHRSSPLLCAGHGMLLVHRRALTAHSGEGLDRSRRGRYCRAWSHSGRWQPSGVNTSPCMHRYNEVSRSQGFGSDASGVRDSRSRASMLQIFHVMALDLVRTRTVCANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFX3</accession>
    <name>W6ZFX3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_39518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964062">
        <property type="protein sequence ID" value="EUC42406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691065.1">
        <property type="nucleotide sequence ID" value="XM_007692875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFX3"/>
    <dbReference type="GeneID" id="19123698"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39518"/>
    <dbReference type="HOGENOM" id="CLU_1895821_0_0_1"/>
    <dbReference type="OrthoDB" id="3687673at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="134" mass="14714" checksum="03BCD4BEEBBD164B" modified="2014-04-16" version="1">MVAKRQQRLVSESYAITNREKLPGIAPTEDRVSRGQFRGRCVIRLGSGDRRVLNHEEDGPAAMERTHKAAETLEATLHHFSCEASETGPLKSEAQGLDLSVPVARSSLAGPFVLPTLLSGDTQYSHWCGNRSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGU7</accession>
    <name>W6ZGU7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_102773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964051">
        <property type="protein sequence ID" value="EUC42726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690762.1">
        <property type="nucleotide sequence ID" value="XM_007692572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGU7"/>
    <dbReference type="GeneID" id="19118154"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102773"/>
    <dbReference type="HOGENOM" id="CLU_185443_0_0_1"/>
    <dbReference type="OrthoDB" id="10340246at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887486" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9788" checksum="D0E7162FA50DF8C8" modified="2014-04-16" version="1">MLRGNTLCFRWGWLGLFPFVTWNNVSEIGGMGVGRGGYGGLWEEERNIKSGLYIYAHTTSHGMKEFTPAGWKHFNRSHVGLHCTALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH67</accession>
    <name>W6ZH67_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">E3 ubiquitin ligase complex SCF subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_102375</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SKP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964046">
        <property type="protein sequence ID" value="EUC42891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690610.1">
        <property type="nucleotide sequence ID" value="XM_007692420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZH67"/>
    <dbReference type="STRING" id="930090.W6ZH67"/>
    <dbReference type="GeneID" id="19118069"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102375"/>
    <dbReference type="eggNOG" id="KOG1724">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059252_4_0_1"/>
    <dbReference type="OrthoDB" id="2342932at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043224">
        <property type="term" value="C:nuclear SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017117">
        <property type="term" value="C:single-stranded DNA-dependent ATP-dependent DNA helicase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101026">
        <property type="term" value="P:mitotic nuclear membrane biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045841">
        <property type="term" value="P:negative regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000018">
        <property type="term" value="P:regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18322">
        <property type="entry name" value="BTB_POZ_SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000026">
        <property type="entry name" value="E3 ubiquitin ligase complex SCF subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028729">
        <property type="entry name" value="E3_ubiquit_lig_SCF_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="7">
        <location>
            <begin position="11"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="6">
        <location>
            <begin position="119"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00045385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR028729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="169" mass="19252" checksum="7AEDC1BFB0739A7C" modified="2014-04-16" version="1">MASTNAEGVKLISITTSDGVNMQVERPVAERSILIKNLLEDLGGESDESIPIPNVNEAVMKKVLEWCTHHKNDPPATQDDDSDSRKKSTDIDEWDQKFMQVDQEMLFEIILAANYLDIKALLDVGCKTVANMIKGKSPDEIRKTFNIQNDFTPEEEEQIRRENEWAEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHC6</accession>
    <name>W6ZHC6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_102147</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964044">
        <property type="protein sequence ID" value="EUC42951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690548.1">
        <property type="nucleotide sequence ID" value="XM_007692358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHC6"/>
    <dbReference type="STRING" id="930090.W6ZHC6"/>
    <dbReference type="GeneID" id="19118015"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102147"/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC43696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJE1"/>
    <dbReference type="STRING" id="930090.W6ZJE1"/>
    <dbReference type="GeneID" id="19117612"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100117"/>
    <dbReference type="eggNOG" id="ENOG502THB6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_934287_0_0_1"/>
    <dbReference type="OrthoDB" id="3689744at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889881" evidence="1">
        <location>
            <begin position="20"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="295" mass="31553" checksum="475863EAB0CF7F65" modified="2014-04-16" version="1">MRVLIAAIALLSIFSDTSSAHPSLFDPRAQTKNIRVPISELLQNSKVEKSGKGTQGPLKFTGTLPPELKALYKSMAPKPDPLKESKMGQNVCLGDPCCTKYNDNKVTPTPVFEVSEWSQHLGLPRRISEALCPPGTVTNSRTVSYSYSINVNIGPDLKFGPAILDKFGIRVGFAYTWGTATTVGYTANCSDGGKYPCYAVFTPRIGVIKGWGYIAQVGTNGFICSKGERSFIEIHVPVVPSDTCKGGDRNPCGPAGVYDHCFATGPQAAALCPRSGVDLKHPPARSCPNSITGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJH8</accession>
    <name>W6ZJH8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_99994</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964020">
        <property type="protein sequence ID" value="EUC43746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691551.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19129582"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99994"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:transcription regulator complex"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000925">
        <property type="entry name" value="Zinc finger protein 668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF20">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="232"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="271"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="449"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="391"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="479" mass="51983" checksum="2DDD4949F3D2013E" modified="2014-04-16" version="1">MELDTILNARLTASLGHGSLFTMQHAMQQQHFGAPPSYLNGGHIKSENGSERGVSPHPSDSSRYSSQQPQQQLPSYPSIPQQHMNGLRYPSPSQMQAPMPMLNNSNYIPNPPDHAYAQQQQMPDNQVQHQHNGGRPASDTGPPKAFACSTCGKGFARRSDLARHERIHSGIRPHVCDYPNCGKQFIQRSALTVHQRVHTGEKPHMCERCGKPFSDSSSLARHRRIHSGKRPYKCPYADCQKTFTRRTTLTRHQNHHTGTVEEAAAATAAALASRASASSRTGRSDGGDYSETASPLGTPSPNDRTLSLSPANGMPAGGMPGLHRQGSDYAYMGGINVPPHMRHEMPQPSPRASPALTAQSYGSNVSGSRPAITSHPSAYGPPPILEPPASANHNQSGGTNSANGSPHMSAMGWQSPGQQALPSPGAGDNGYVYPEPQYQAQNGMYYQHNNIRRPNSTEPDHYNPNQQRMGNEMWAPAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJN4</accession>
    <name>W6ZJN4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_99943</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964019">
        <property type="protein sequence ID" value="EUC43806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJN4"/>
    <dbReference type="GeneID" id="19129571"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99943"/>
    <dbReference type="eggNOG" id="ENOG502RXEE">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_0_2_1"/>
    <dbReference type="OrthoDB" id="10000533at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF4">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC43806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="319" mass="35727" checksum="8BA595DA1F09B41A" modified="2014-04-16" version="1">MVKIAVAGGTGNVATCMLKEIIASNQHDIIIFTRSAPSKPHPSPRVSYLQVDYTSRDALTTALHGVHTVLSFFVVHLDVDNIGQKNLIHASITAGVSRFAPSEWSIASYSRIPTYDVKDQVRSYLEDLDAKGELNGMQYCLFQPSIFMDYFAHPYPLEPELITWPFFVDYENRRAMLLDEGDQPIVLTAMQDDAAILAKALADTERPWPKVGGIRGCQTTINEIIALGKKLRGGEWSIERVSSADIKAGELKTSWIPTFTHPTVPADQQDVFSKAFVIMFMQAILNGSWNVSAEWNERFPDHKFMGLEEYLTKAWEGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJU8</accession>
    <name>W6ZJU8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar protein sorting 55</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_6731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OB-RGRP/VPS55 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964017">
        <property type="protein sequence ID" value="EUC43866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689588.1">
        <property type="nucleotide sequence ID" value="XM_007691398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJU8"/>
    <dbReference type="GeneID" id="19125059"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6731"/>
    <dbReference type="eggNOG" id="KOG2174">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134810_0_1_1"/>
    <dbReference type="OrthoDB" id="14246at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034424">
        <property type="term" value="C:Vps55/Vps68 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007262">
        <property type="entry name" value="Vps55/LEPROT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050">
        <property type="entry name" value="LEPTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050:SF0">
        <property type="entry name" value="RH04491P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04133">
        <property type="entry name" value="Vps55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC43866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="13696" checksum="2125A04580A53ED4" modified="2014-04-16" version="1">MAGIKTIIGLSFVLAIGFLLVILSAALFHNYLTLLVVATYVIAPLPNWLCSRAANHDDFMESSGNGVVDFGRFLTGFFVVMGIALPTLLWHSAEIAGGAAAMSIFGGLLIYATIISFTLFFQEQEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJY5</accession>
    <name>W6ZJY5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MalT-like TPR region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_32428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683172.1">
        <property type="nucleotide sequence ID" value="XM_007684982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJY5"/>
    <dbReference type="STRING" id="930090.W6ZJY5"/>
    <dbReference type="GeneID" id="19122102"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32428"/>
    <dbReference type="eggNOG" id="KOG1840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053909_0_0_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="43805" checksum="5D3D5ADEB77E919D" modified="2014-04-16" version="1">MEVAFRDNTRYKGSANAVATTWVVSFSQLRERDTFAADLLEFISCIEWKAVPWYLLPKRDSEEEMENAIGTLCRREEDHTEPDEEEWYDTHRLVHLATRIWFNKNDNSSKVVKDAIRHVAHVFPFTAYDRELIIWRAYLPHSLRLLNGGQHCNKSDISELCLRVGICLGKNGRLRESLVWVEKACQQRDHLSEDDPERLASQYHLAIIYTLDRQMENSILLLERIVQVRMKTPYSERPSLLASLDAPARAYALNGQGHKAREILERVVEAEEKTLPPENYQLLLLQQTLARAYEACNQMHKAVPLHEKVVRTREKILAPGHPDILHAQHTLARSYLLAGQEQRAVPLLEQVIDARDTTLSSEHPNRREPCMHAPPSQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKJ2</accession>
    <name>W6ZKJ2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_88695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685537.1">
        <property type="nucleotide sequence ID" value="XM_007687347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKJ2"/>
    <dbReference type="STRING" id="930090.W6ZKJ2"/>
    <dbReference type="GeneID" id="19127330"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88695"/>
    <dbReference type="eggNOG" id="KOG0802">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005224_1_0_1"/>
    <dbReference type="OrthoDB" id="1305878at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.90:FF:000039">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052256">
        <property type="entry name" value="E3_ubiquitin-ligase_CHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16079:SF4">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16079">
        <property type="entry name" value="UBIQUITIN LIGASE PROTEIN CHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="20"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="256"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="680"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="412"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="685"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="914" mass="101549" checksum="240A1154476F634F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL58</accession>
    <name>W6ZL58_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA mismatch repair protein S5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_648</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC50800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684457.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZL58"/>
    <dbReference type="GeneID" id="19124969"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_648"/>
    <dbReference type="eggNOG" id="KOG1979">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004131_2_0_1"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061982">
        <property type="term" value="P:meiosis I cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MutL_Trans_MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000033">
        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032189">
        <property type="entry name" value="Mlh1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF12">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16413">
        <property type="entry name" value="Mlh1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="7">
        <location>
            <begin position="247"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="385"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="664"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="667"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="741" mass="82154" checksum="219ACDC644FDCA61" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLS8</accession>
    <name>W6ZLS8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_87477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685097.1">
        <property type="nucleotide sequence ID" value="XM_007686907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLS8"/>
    <dbReference type="STRING" id="930090.W6ZLS8"/>
    <dbReference type="GeneID" id="19127072"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87477"/>
    <dbReference type="eggNOG" id="KOG0832">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040318_4_2_1"/>
    <dbReference type="OrthoDB" id="2320368at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000061">
        <property type="entry name" value="40S ribosomal protein S2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_uS2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_uS2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="43669" checksum="0480F3FCA32720FE" modified="2014-04-16" version="1">MIVRSIAARTGSRALAPRQSRPLRRFFSTDIAAIQASTDNSLEQVQSLEAQLNTHLHQPLPSIDADSQSRDHVAAQYHLYKQQAKMLGKLGSDIAPHYRPHTLLNHPPSPADVTLELLLASEAHQGHVTSLWNPANARYIHGIRQGVHIISLEVTAAHLRRSAKVVQEVARRGGMILFVGTRDGQDRAVARAAELAKGYHLFERWIPGSITNGQQILGRCRTKVVNELDEEVKGFDEQLYDRPALRPDLVVCLNPLENYVLLHECALNNIPTIGVIDTNADPTWVTYPIPANDDSLRCIQVIAGVLGRAGEAGQKQRLAAAAEGKITYRPAQGLTLAGADADADKSGASTLRMGEAAPRGHVAEAVQSGLDNASDMAVQMDEVNSRESHRTRGGRDIKVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMI0</accession>
    <name>W6ZMI0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase metallopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_86382</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="7">Can bind about 5 Ca(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684757.1">
        <property type="nucleotide sequence ID" value="XM_007686567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMI0"/>
    <dbReference type="STRING" id="930090.W6ZMI0"/>
    <dbReference type="GeneID" id="19126845"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86382"/>
    <dbReference type="eggNOG" id="KOG1565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_711734_0_0_1"/>
    <dbReference type="OrthoDB" id="65569at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030574">
        <property type="term" value="P:collagen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021190">
        <property type="entry name" value="Pept_M10A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201">
        <property type="entry name" value="MATRIX METALLOPROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201:SF323">
        <property type="entry name" value="MATRIX METALLOPROTEINASE-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00138">
        <property type="entry name" value="MATRIXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase metallopeptidase" evidence="8">
        <location>
            <begin position="3"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC48734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="388" mass="42331" checksum="EAFE02E194B98968" modified="2014-04-16" version="1">MNSAPLNIMQAASNVKADINIRFVPINSNRTVAVTTIDSDGVYFTPGKINITFNDNEQWTDDILFSTTAVHEIGHALGLSHSTVPSAIMFAYYDGLMHPVHPDDKMGIHSIYGWKTPKWKLINSGSKISSIIQITSSSSTPAPNDGLYQMRPTGQILRYINNAWTTVDNYKETAQIAGANGILYQRHYDGGTFRWTGTPSNWQSISPTDTSILDIYAASDQLYARRKDGSVVRLSGSNWLTIDQTSPGSRQIAVSDDKTLWNLIANGDLVRSRWPYTSAAILDRNAANIGIAVGGNEFFKVQSDGLVVWLDTKGPYWSVIEEKGSVGIHAVGELLYSRHADGTVWRWTGIPGLWEGIDERGGAGGVAGDRAGGVWGLLGGSEVWVHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZML3</accession>
    <name>W6ZML3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GCN5-related N-acetyltransferase Rv2170-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_2427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684691.1">
        <property type="nucleotide sequence ID" value="XM_007686501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZML3"/>
    <dbReference type="GeneID" id="19120563"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2427"/>
    <dbReference type="eggNOG" id="ENOG502SDQB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030809_0_0_1"/>
    <dbReference type="OrthoDB" id="61870at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053225">
        <property type="entry name" value="Acyl-CoA_N-acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="GCN5-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958:SF6">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GCN5-related N-acetyltransferase Rv2170-like" evidence="1">
        <location>
            <begin position="250"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="356" mass="39192" checksum="690DE0AAE6CC90D9" modified="2014-04-16" version="1">MQVHAHSATSPGLQRALKSALPYSINLVYRTQHPNRTAHAHILATFPESTSPEATVPECWAAAYLDRSMRPETELWIFSTLELPHHQPSTTSSSTGDGGGKYCGECKKAVLALVDYMSTLPTPLMRPDNLPAMDLAKQHEREHPTPPPSGAYESAPGTYMRHLLLPKAITVGACQRDVLQILHEAGVVRTELPGPDAELNKFLFKHSDLPETRELPARLRWGEIREQDIGTVQARTSIPRTRSTLMSLKSVGVFEEETDMPVAWTFLGLDGSLVTLHTGEAYRGKGIAKAVATRLFKEHARGLAVDVNGDSWSHADVYTGNIQSESVCRSLGGKALWKCFWLRIDLERAGNLVSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMR4</accession>
    <name>W6ZMR4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pleckstrin homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_21260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="Han J."/>
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                <person name="Lindquist E."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
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                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="1">Belongs to the aldose epimerase family.</text>
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    </dbReference>
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    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC49704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36891" checksum="317D22F741F3CA70" modified="2014-04-16" version="1">MSSKAFTFLPLGAIIQKFHVNGKNIVQGFPSADLYKQYNAPFFGETIGRIANRVSKAKINDLNGKSYQLPLNDGPNSLHGGHMGWGKREFEGPTTVDRNGKEATLFKYLSKDGEEGYPGTVQVSVWYVQEKEQVDGVQQEVLHIEYEAELVGDEVDETAINMTNHSYFNLTEGPSIAGTEVTLITNKYQVVDDGGIPTGPIEEYPGVSPQKTFTLGEKEPDIDDCFVVNTDPSSVPIDTRSLALQKLASFYHPESKIHLEVHSTEPAFQFYTGKYIDVPAVGDVPARRARSGFCVEPSRYVNAINVPEYKPMMVLKKGQKYGTKIVYRGWHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSA4</accession>
    <name>W6ZSA4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_32223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683017.1">
        <property type="nucleotide sequence ID" value="XM_007684827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSA4"/>
    <dbReference type="GeneID" id="19122051"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32223"/>
    <dbReference type="eggNOG" id="ENOG502SUY5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087351_1_0_1"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="211" mass="23176" checksum="DBC5B277581274F7" modified="2014-04-16" version="1">MNDPIADAKAQEATRNYEFRIATPDDIPALQQMIGDSLRALGKGYYTEAELDGSIGYLFGPDSVLIHDQTYYILHPTSQPTTICACGGWSFRKTLYGGDSAPSVLRMPAKRDPSVERASIRAIFTSPAYARRGLGTMMMRHCERAAQQGKAGETLGFSRLEMGATLSGVQLYERCGYVRSGREDVVTCPNGEGIRILHMTKDLEEEEADAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZW23</accession>
    <name>W6ZW23_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_88591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC48011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685545.1">
        <property type="nucleotide sequence ID" value="XM_007687355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZW23"/>
    <dbReference type="GeneID" id="19127310"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88591"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010119_4_0_1"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="170"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="334" mass="37573" checksum="8730F2B2403D4B07" modified="2014-04-16" version="1">MAISESIIVSKSLPTIHLDLLRANNVQESKNLLNACRSHGFFYLDLNSDPELCNLWKKMLQNIAQYFNQPLDIKMRDARGSDNFGYEPMGTEAGPNPKTRDGYESLKFSRREFLKGSSDLTTSIRAKEDCFFSFIDHAHTITLMILSRLSTQLGLTGTSRFEAHHADPGPSLSTLGLLRYPKHEGASATEPQNVGHNKHTDVGTLTFLLAAQWGLQYLSLTSRRWEFIEPRAGHAIINVGDSLRFLSGGKLASVVHRVVPLHRTQLEDRYSMAYFLRMNDGGIFNDTSSKKWTAKEWHDFKFGVFKDPSTLDAEGRFLTGMMIEESEGPILVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWL0</accession>
    <name>W6ZWL0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_88245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685364.1">
        <property type="nucleotide sequence ID" value="XM_007687174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWL0"/>
    <dbReference type="GeneID" id="19127227"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88245"/>
    <dbReference type="eggNOG" id="ENOG502S51X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_548564_0_0_1"/>
    <dbReference type="OrthoDB" id="5423707at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000637">
        <property type="entry name" value="HMGI/Y_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013268">
        <property type="entry name" value="UTP16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08297">
        <property type="entry name" value="U3_snoRNA_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00354">
        <property type="entry name" value="HMGI_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="264"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="497" mass="53815" checksum="EC83653CCAD71F21" modified="2014-04-16" version="1">MVTTRGGTETPGAPTPTPRSSTRKQVGKRELESLETPTQTKRQRKAPKATAKKGSAAESKGQEESADEPSQESSNDTSDTIAANAQEPEAPETPKQSGLPARRKSSPQVVVGADASDQSSNTVEKEDEVPSTVQNPAFYTPIQAPGSVYATPATRKRPEGSPTPKAKILNDQTPSTAVKKGRGRPKKTPQKELVEAIDEVPSSTYESEMAPIPSQDAAPPSAQPEKAHMRFGSEEPAPTPASPVINKQGNKRYEASEPVVEVSQADDDSDASDSDDEAPEVVTTAAASSKALAARAEADRAQKAQQAKEDAKRKAREEFLAAQQAAKREREEKKAKKLAKQAAKEAKAAAAADAPPTDQESESEYPTQIDTSNGLLPASLLATIDDQRPPTPPPERRGKTEEEKRKEKLNQHIKFLERTDKPAKDVKKGKLNVAVLAQQNKVMPPKVNRDSKNVREHWLKGRQVEKRMVGKKGGVVRVGRMERRPHGNRGFLRDGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZXN4</accession>
    <name>W6ZXN4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_33925</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684839.1">
        <property type="nucleotide sequence ID" value="XM_007686649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZXN4"/>
    <dbReference type="GeneID" id="19122441"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33925"/>
    <dbReference type="eggNOG" id="ENOG502SPMQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046066_1_0_1"/>
    <dbReference type="OrthoDB" id="1263307at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF13">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="7"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="270" mass="29259" checksum="D1E892C79746B233" modified="2014-04-16" version="1">MSSRPTVVLVPGSFCSANAYDVIVTPLRSKGYDIQVIEPPCYPAGYGRKSDGPPPNMYADAQYINKHVEKLADEGKEVVLVAHSYGGVPATQSLKGVTKKEREQQGKPGGVVRIAYLTALVPRLGETSFQVLGDQGGVVPSAGEDGWMYHADPAPVAAQVCSDIPLADAIVEVSKMGRHFGACFLDPLTHMGYKDVPASWFFCGKDLVVTPDAQQKGIEAIEESWVGTEREGKKVDVTRLECDHYPLVLEDRRAKVEAWVEGLVEKGGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZXN9</accession>
    <name>W6ZXN9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_86901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684874.1">
        <property type="nucleotide sequence ID" value="XM_007686684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZXN9"/>
    <dbReference type="STRING" id="930090.W6ZXN9"/>
    <dbReference type="GeneID" id="19126949"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86901"/>
    <dbReference type="eggNOG" id="ENOG502S8B6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027006_1_0_1"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="497" mass="53870" checksum="715BAE94ECD34F6C" modified="2014-04-16" version="1">MDTTFITIHDLSDDAHILYSSDSIVDILGHTPDEVVNRSVWQFFHPDELPLAKAQHSRGVRLDKAAVLSYCRLKNRQGEWVGCECCFSVVHDVLVCCTSVYRQGMQSQKRAVEAPIVRKLFASSPKDPRYHMLSHLSTKFDLGHEDQTHEPRAALFLNRFTRTLTVMYATSGIEQIIGISSEAMKGRSFYYCIAPNCLEDAVRCLESAKGNDSIAYMRFFFRDPRQDDPPEASSSESEDDIMTDVTSSDEESEGGVGLGTSGDASSRQPSVANNSTNGSAEASASRSNSREDPSYRSAGSATHQAMLGGSAPRSSISSASSSRSEPRDEPIELEAVISCTSDGLVVCLRRARPMLPGAMPVAQPAHQYNGIFAAPWATQPVFHPALPQMPQYPLGARHPAMAHAGPSMDFQNSFMKSIRDVAVFAWALTGINGSLVDYARGKPVGESQPRDGFSIWNPLPEPTGFGGKQLSVPPSGYGSGSNSSASNDPFGFGDPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYG6</accession>
    <name>W6ZYG6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA mismatch repair protein S5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_33776</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684717.1">
        <property type="nucleotide sequence ID" value="XM_007686527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYG6"/>
    <dbReference type="STRING" id="930090.W6ZYG6"/>
    <dbReference type="GeneID" id="19122403"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33776"/>
    <dbReference type="eggNOG" id="KOG1978">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011171_4_1_1"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000017">
        <property type="entry name" value="PMS1 homolog 1, mismatch repair system component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
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        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF41">
        <property type="entry name" value="MISMATCH REPAIR PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
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    </dbReference>
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        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="229"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="440"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="640" mass="70093" checksum="4DDF80923CD19783" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYH8</accession>
    <name>W6ZYH8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pal1 cell morphology protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_23490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYH8"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_23490"/>
    <dbReference type="eggNOG" id="ENOG502RB1B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037771_1_0_1"/>
    <dbReference type="OrthoDB" id="5389892at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013226">
        <property type="entry name" value="Pal1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307:SF1">
        <property type="entry name" value="PAL1 CELL MORPHOLOGY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08316">
        <property type="entry name" value="Pal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="374"/>
        </location>
    </feature>
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        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="41328" checksum="AEA8D6AA4FA0B4CB" modified="2014-04-16" version="1">MEAAHRAIIDPLIEPDPSDVTGLNSHFRSTFAPAAPITPPGESPKEHPSVNIQHTGSSTSTNPFRRSRAASDTKGASASVTNYGYSSSHSRRNDYPSPPSSASPKHTRFPNNHRAEAFGSMNEAKPRRASNPPPSTLNNGLTRGNSLKERYPGDKSHRPLDQLRHDEKVAHRAPHLRKKNMQGADIIDRLDKASILRYHHEGPYDAASIARNRVEKYSPLAAVKDSNEEALKATPRENIIDSLQRHRPLEGVANIPPGMPDRFGRVLDYEEGADLQREPGGDYRRWPGVQYHPDDLKGKGEPSFTIERALKEHKRTGDSGTEMKTRSRRAHSAGHTDAAAAYGASSNDHAEKSMGSAIKRRIGSLRRRKQDPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W7A075</accession>
    <name>W7A075_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A075"/>
    <dbReference type="GeneID" id="19120359"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22995"/>
    <dbReference type="HOGENOM" id="CLU_1669067_0_0_1"/>
    <dbReference type="OrthoDB" id="10456281at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="158" mass="17197" checksum="1888C760DDE2CEDD" modified="2014-04-16" version="1">MTPSAGLAFRGGCRAGQAGQADHDCVATGTSRRRQPWLLDGHRGCRWRKRLLADGHVGAEGTTSRHSSDRLRLHPWPSPDKRSVPRVLDPPEPAWTKRGHGKLWSPLTNPPLGQEHAQKKFPSSGTAWRASSAPQRTTASGTHAALGPRTAPRRVCAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0G8</accession>
    <name>W7A0G8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Arginase</fullName>
            <ecNumber evidence="2 11">3.5.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_84533</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>L-arginine + H2O = urea + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:20569"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="EC" id="3.5.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="11">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.1" evidence="2 11"/>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684030.1">
        <property type="nucleotide sequence ID" value="XM_007685840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0G8"/>
    <dbReference type="STRING" id="930090.W7A0G8"/>
    <dbReference type="GeneID" id="19126482"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84533"/>
    <dbReference type="eggNOG" id="KOG2965">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_6_1_1"/>
    <dbReference type="OrthoDB" id="9992747at2759"/>
    <dbReference type="UniPathway" id="UPA00158">
        <property type="reaction ID" value="UER00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09989">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000009">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014033">
        <property type="entry name" value="Arginase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01229">
        <property type="entry name" value="rocF_arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782:SF3">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC49521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="324" mass="35068" checksum="84D16BA3587962B4" modified="2014-04-16" version="1">MTSAPTKQPNFLPSRHELGIVAVGFSGGQPKAGVDAAPMALIENGLIKQLEEDLEYNVTYDGQVHNYSELQPTEDPDYRGMKRPKFASAVTHEVSNQVYKHAKDGKLVLTLGGDHSIAIGTISGTAKAIRERLGREIAVIWVDAHADINTPETSESGNIHGMPVSFLTGLATEDREDVFGWIKEEHRLSLKKLVYIGLRDIDRGEKKILREHGIKAFSMHDIDRHGIGKVMDMALGWIGSDTPIHLSFDVDALDPMWAPSTGTPVRGGLTLREGDFIAECVAETGSLIALDLVEVNPSLDAEGAGDTVRAGVSIVRCALGDTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2L0</accession>
    <name>W7A2L0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_82773</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683355.1">
        <property type="nucleotide sequence ID" value="XM_007685165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2L0"/>
    <dbReference type="GeneID" id="19126124"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82773"/>
    <dbReference type="eggNOG" id="ENOG502QVWE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003680_0_0_1"/>
    <dbReference type="OrthoDB" id="10057598at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14518">
        <property type="entry name" value="Haem_oxygenas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01236">
        <property type="entry name" value="Haem_oxygenase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="735" mass="82880" checksum="B533F5602104B30E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4P0</accession>
    <name>W7A4P0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aromatic prenyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_31681</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tryptophan dimethylallyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682368.1">
        <property type="nucleotide sequence ID" value="XM_007684178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A4P0"/>
    <dbReference type="GeneID" id="19121932"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31681"/>
    <dbReference type="eggNOG" id="ENOG502S2XP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037431_2_2_1"/>
    <dbReference type="OrthoDB" id="3354387at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13929">
        <property type="entry name" value="PT-DMATS_CymD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033964">
        <property type="entry name" value="ABBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012148">
        <property type="entry name" value="ABBA_DMATS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017795">
        <property type="entry name" value="ABBA_NscD-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03429">
        <property type="entry name" value="arom_pren_DMATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40627">
        <property type="entry name" value="INDOLE PRENYLTRANSFERASE TDIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40627:SF4">
        <property type="entry name" value="PRENYLTRANSFERASE ASQH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11991">
        <property type="entry name" value="Trp_DMAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000509">
        <property type="entry name" value="Trp_DMAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00036">
        <property type="entry name" value="Aromatic_Prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01162">
        <property type="entry name" value="I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000509-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC51126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="51093" checksum="1E6521C7287908C5" modified="2014-04-16" version="1">MQIIRLYRRIRSLAARKPKEPKKVKQKSLGVWLSLNESLTVFDEDTRFWWEITGPILARMMELMGYDQDTQHKHLLFYYMYILPALGRRPSSDGHPNGWESFMTDDCSPLELSWEWGMSAGESRVRFSIEPIGKYAGNSADPLNEKMVFQLIDTLRPAFHKSLDLTIFNAFSEALTTTHKKLDTKHISVNGRSQHFVAFDLDVGTPSLKAYFIPGLKAVETDTPVPELVVQAIDSCKPHLGHVFMNNFRRFNSDLTNFSKTSPSRPQIEIIGIDCVVPIKSRVKIYVRHRETSFDSVCRMLSLGASKPIDPGSLASLHELWSLVLDLPEYFPSNQELPNVPHRTSGILYYFEIKPTSYDIVPKVYIPVRHYAKNDLSIAQGLATYFERRGQSATADKYVQALSDIFSHRSLDSGLGLHTYITCALKKTGLSVTSYFNPEIYHPNRYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W7A581</accession>
    <name>W7A581_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_21254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682089.1">
        <property type="nucleotide sequence ID" value="XM_007683899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A581"/>
    <dbReference type="GeneID" id="19120029"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21254"/>
    <dbReference type="HOGENOM" id="CLU_105111_0_0_1"/>
    <dbReference type="OrthoDB" id="3798952at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="231" mass="25196" checksum="01F10B36620706E4" modified="2014-04-16" version="1">MVTLSGLSHMLRSTQLLSIRAEKLEETESALPGIKRGIAIGAACSVSVVLIAILAFLAIRRRNRILAQRLQHQTPEARGVEAQPQEKTWWPHAPPPVLPVATLPPPPPPVEVDAHIIHELDAGQTPELHGETRPQEVDGIGKPQNAPEEAEELYVQRLKQWKDWNTVSEADPAQPNNEVTRWSVPLLMVSPPGTTRGDVSPLLRSSWDLSSRGASPISPPATAHFPPGHVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6YKI7</accession>
    <name>W6YKI7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_10266</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964283">
        <property type="protein sequence ID" value="EUC39672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693811.1">
        <property type="nucleotide sequence ID" value="XM_007695621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YKI7"/>
    <dbReference type="GeneID" id="19118127"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10266"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000180">
        <property type="entry name" value="MFS monosaccharide transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF6">
        <property type="entry name" value="MSTA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="17"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="495"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC39672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="525" mass="58054" checksum="8874AD06E94A5CAB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YKZ9</accession>
    <name>W6YKZ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidase ustYa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_110313</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964233">
        <property type="protein sequence ID" value="EUC39872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693612.1">
        <property type="nucleotide sequence ID" value="XM_007695422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YKZ9"/>
    <dbReference type="GeneID" id="19119579"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110313"/>
    <dbReference type="eggNOG" id="ENOG502SNCH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_4_0_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC39872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="31214" checksum="019E54B8750188D2" modified="2014-04-16" version="1">MSIATQQGRDERYNAIGCTCNGLGTSIHSGVSNSDNEDAVVLRQRRISTWTTVQKYWWLINTTLFLTIIILLMNERGRYQTTNSQWSLTGDISGFAPLFSQKIVSFKPNPIFTPEDASDFWSNETQEAWLSIVPEGLGYVNVKNASDYPNLPQPLHHYPGRTVFTTSVTHQLHCLYVILKAYNSMKLIGTEHKLTKPYTPEDPWHLNHCFDYIRQAIMCAGDVALEGAATTFPVDEHGRDRGGSDEWDAVHVCKDYSQIYSYLEKESASHKKWIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YL72</accession>
    <name>W6YL72_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_31016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="19121786"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31016"/>
    <dbReference type="HOGENOM" id="CLU_1948453_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="129" mass="13699" checksum="3B666D2A8A24A0C2" modified="2014-04-16" version="1">MSLTEIHPSRSSQLQTMTTTIIVARFIATTPITAFIAALAITLIVTFLAALAVAFVTTVVDAFVVALVTVSIMAFVAIFVVAFVVAFIAIFVVVFITASISYILLTAIILCANAEPRVFVILVFVLKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLE7</accession>
    <name>W6YLE7_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_10008"/>
    <dbReference type="HOGENOM" id="CLU_2263276_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="103" mass="11816" checksum="0B338864DA35DF44" modified="2014-04-16" version="1">MSQNQLHFAEKNCRLLERIEEFLANYTQDAKMEESEPIMENIEAHLPAEQDVVDHNVEPTNPDHGECDSAAPVDLDHGPFMQNIHFESLPANWQNEVGMHSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMR0</accession>
    <name>W6YMR0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_108454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964154">
        <property type="protein sequence ID" value="EUC40572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692904.1">
        <property type="nucleotide sequence ID" value="XM_007694714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMR0"/>
    <dbReference type="GeneID" id="19119249"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108454"/>
    <dbReference type="eggNOG" id="ENOG502T2GE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103848_0_0_1"/>
    <dbReference type="OrthoDB" id="5377226at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="249" mass="27777" checksum="67217B1EB1A0BA60" modified="2014-04-16" version="1">MVYITSDLFGPSTARDWQQDNTSHNWHTMAPDQPAAGLGKRKRQAGDDKPQLYERPCTSLHTSGTDISPKTIPRHHRSSLSRDTTRLHHPNTPPFDSNNNTLSYAFLPSKAHDFPSDRRPVKQLKRFSPKASLVKSTSHLMDIDLDVQSPTTTTTTTTTTTTTTTTCGTPAHHHAVSDLRSCHACQKAPTRKKDLENYLDCRRCEGRTCFICARQCVGCAKAICKKCIVEVGEEGDAWCLDCYSRTINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMY0</accession>
    <name>W6YMY0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_41068</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 81 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="KI964149">
        <property type="protein sequence ID" value="EUC40647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692848.1">
        <property type="nucleotide sequence ID" value="XM_007694658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMY0"/>
    <dbReference type="STRING" id="930090.W6YMY0"/>
    <dbReference type="GeneID" id="19123991"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41068"/>
    <dbReference type="eggNOG" id="KOG2254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005482_2_0_1"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1170">
        <property type="entry name" value="glycoside hydrolase family 81 endo-[beta] glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040451">
        <property type="entry name" value="GH81_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="ENDO-1,3(4)-BETA-GLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983:SF0">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-D-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03639">
        <property type="entry name" value="Glyco_hydro_81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52008">
        <property type="entry name" value="GH81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 81 N-terminal" evidence="10">
        <location>
            <begin position="74"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 C-terminal" evidence="11">
        <location>
            <begin position="410"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="785" mass="88847" checksum="1375F5DB08A31749" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPL0</accession>
    <name>W6YPL0_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_111508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_111508"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
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    </dbReference>
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    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="53" mass="6136" checksum="C041C7C4F99783DD" modified="2014-04-16" version="1" fragment="single">NISLINLLLLRGTLVNITNINNITLLYYYVKYSYKSIIELLLKNSLSINISVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRD4</accession>
    <name>W6YRD4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_109497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964191">
        <property type="protein sequence ID" value="EUC40165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695131.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19119445"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109497"/>
    <dbReference type="eggNOG" id="ENOG502SVMZ">
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    </dbReference>
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    <dbReference type="OrthoDB" id="3941538at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
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        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="700" mass="76068" checksum="219857BADA6ED89C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTS8</accession>
    <name>W6YTS8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ribosomal RNA small subunit methyltransferase NEP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_107518</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964130">
        <property type="protein sequence ID" value="EUC40938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692553.1">
        <property type="nucleotide sequence ID" value="XM_007694363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTS8"/>
    <dbReference type="STRING" id="930090.W6YTS8"/>
    <dbReference type="GeneID" id="19119065"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107518"/>
    <dbReference type="eggNOG" id="KOG3073">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055846_1_1_1"/>
    <dbReference type="OrthoDB" id="269804at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005880">
        <property type="term" value="C:nuclear microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070037">
        <property type="term" value="F:rRNA (pseudouridine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18088">
        <property type="entry name" value="Nep1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1280.10:FF:000003">
        <property type="entry name" value="Ribosomal RNA small subunit methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005304">
        <property type="entry name" value="Rbsml_bgen_MeTrfase_EMG1/NEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636">
        <property type="entry name" value="NEP1/MRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636:SF5">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03587">
        <property type="entry name" value="EMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="30658" checksum="5DDE94E9BCDEBB9D" modified="2014-04-16" version="1">MAPMKIESPKSPAERPSSRGSPDRAKKRARTQSMPPPELPRLVAEQHAPIPTNDKDTQRLIVVLCSATLETYKASHGNGRGPGAREDKYNLLNSDDHIGVMRKMGRDISEARPDITHQCLLTLLDSPINKAGRLQIYIHTSKNVLIRVSPTVRIPRTFKRFAGLMVQLLHRHQIRSTTSQEKLIEVIKNPITDHLPPNCRKVTLSFDSEVVRVSDYIGSLNKGESIAVFVGAMAKGNDDFADDIKDDSIAISQFNLSASVACSKFCHAAEDVWNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTV0</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964125">
        <property type="protein sequence ID" value="EUC41005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTV0"/>
    <dbReference type="GeneID" id="19128017"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9213"/>
    <dbReference type="eggNOG" id="ENOG502S0NF">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033551_0_0_1"/>
    <dbReference type="OrthoDB" id="5552418at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="392" mass="43373" checksum="6CE7E6BE9C13B639" modified="2014-04-16" version="1">MDNDRRPRHTPSGYASQQGTLLPPQASYPVVSAPDRFRQPPLTTPAPPTSLPSSGSRASPQGYGYAYGESAQFGSSVQPSNVSYSAQDYGTDQQQQAQRTPQQYSPYGQNIMYGAQASATGSSQYEPVEQYQQNRDSAIQVLSTGFGVAQQQYYEGGPTSAPAATIASQSVPSQYPSLAYTASQTQVGREALAPAYSAAGMTDPNQATSQPGYPQANYSESQSASGNDYDDFYRTYQSELKKTFEHVRDSRLSEAGTMLFRMSDWLLHFAETLAGLVRDDETYYQQRLQLWEEFNTCWLSTLQKQKAMTQEMINTGQRPQAPKSLIDYDFLEKMGTQLVKNCDSMEKHGLVDYQMGVWEEEIVAMLTSCMDLLEEVGAGPSAQRPTSTARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU53</accession>
    <name>W6YU53_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_102061</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964043">
        <property type="protein sequence ID" value="EUC42987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU53"/>
    <dbReference type="STRING" id="930090.W6YU53"/>
    <dbReference type="GeneID" id="19118002"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102061"/>
    <dbReference type="eggNOG" id="KOG2318">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010564_0_1_1"/>
    <dbReference type="OrthoDB" id="431825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039754">
        <property type="entry name" value="Esf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012580">
        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056750">
        <property type="entry name" value="RRM_ESF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202:SF0">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08159">
        <property type="entry name" value="NUC153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25121">
        <property type="entry name" value="RRM_ESF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ESF1 RRM" evidence="7">
        <location>
            <begin position="177"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="NUC153" evidence="6">
        <location>
            <begin position="626"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="239"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="396"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="643"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="247"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="501"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="646"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="707" mass="79251" checksum="53EA4E90C9D8E004" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUI0</accession>
    <name>W6YUI0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF1772 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_106773</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the anthrone oxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964115">
        <property type="protein sequence ID" value="EUC41190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692292.1">
        <property type="nucleotide sequence ID" value="XM_007694102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUI0"/>
    <dbReference type="STRING" id="930090.W6YUI0"/>
    <dbReference type="GeneID" id="19118919"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106773"/>
    <dbReference type="eggNOG" id="ENOG502SR2H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105974_0_0_1"/>
    <dbReference type="OrthoDB" id="5954308at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013901">
        <property type="entry name" value="Anthrone_oxy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042">
        <property type="entry name" value="ANTHRONE OXYGENASE ENCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35042:SF3">
        <property type="entry name" value="ANTHRONE OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08592">
        <property type="entry name" value="Anthrone_oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC41190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15404" checksum="9CA8F8034507DB36" modified="2014-04-16" version="1" fragment="single">LLGTMLSLSAIAIPVYLDTLRTPAQLYSSWARTYHYGHLGLPAMSITTCILYGIVAQKHKSANRQWRRYVLAALVTVTMVPFTWVFMTSTNNTLFGLHAESEAVGGSFSDARELVVHWSRLHLLRSLFPLAGAVIGIGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUK1</accession>
    <name>W6YUK1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964114">
        <property type="protein sequence ID" value="EUC41208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692259.1">
        <property type="nucleotide sequence ID" value="XM_007694069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUK1"/>
    <dbReference type="GeneID" id="19127667"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9036"/>
    <dbReference type="HOGENOM" id="CLU_033443_0_0_1"/>
    <dbReference type="OrthoDB" id="3694239at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="583" mass="63750" checksum="40D0C0F064699CFB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV27</accession>
    <name>W6YV27_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peptide hydrolase</fullName>
            <ecNumber evidence="11">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_101281</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="11"/>
    <dbReference type="EMBL" id="KI964034">
        <property type="protein sequence ID" value="EUC43292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690209.1">
        <property type="nucleotide sequence ID" value="XM_007692019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV27"/>
    <dbReference type="GeneID" id="19117845"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101281"/>
    <dbReference type="eggNOG" id="KOG2195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025866_0_0_1"/>
    <dbReference type="OrthoDB" id="2214at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03879">
        <property type="entry name" value="M28_AAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000042">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="8 11" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005151129" description="Peptide hydrolase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="12">
        <location>
            <begin position="159"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC43292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="378" mass="41234" checksum="5442EBA635E449BC" modified="2014-04-16" version="1">MKSLSLLATVCATAALAKGPERVSNAARSITIEVAPGETRQITEDERWDIATGGGCGSHFFDITDSFAEPIAVTRAAAYPTTFQYSANIKRLFPSLSWANIKKNLEQYSTFHTRFSETQSGADAAQWLLAQVQAVVKAANKPGVSASAFPHSLWPQNSIIARIQGRSNRTVVVGAHLDSINSANRLTGRAPGVDDDGSGSMLLLEALRVLLTDSAFAGSSPLLENTIEFHWYAAEEGGLRGSQDIFTQYKNAGRDIWAMLQQDMVGYTKGTLNAGKPESFGLITDFTDAVLNRYLVGVIGEYTDITYVNSTCGYACSDHGSAMRSGYPASFVFESDFRYRNPYIHTPNDTMEHMDPNHVLQHGRLVLGYLYELGFSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVM4</accession>
    <name>W6YVM4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C4-dicarboxylate transporter/malic acid transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_105732</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964095">
        <property type="protein sequence ID" value="EUC41605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691892.1">
        <property type="nucleotide sequence ID" value="XM_007693702.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6YVM4"/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Manning V.A."/>
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                <person name="Han J."/>
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    <accession>W6YWP6</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964219">
        <property type="protein sequence ID" value="EUC39949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007695350.1"/>
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    <dbReference type="eggNOG" id="ENOG502SH56">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA_brk_join_enz"/>
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        <property type="entry name" value="DUF3435"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535">
        <property type="entry name" value="FLUG DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535:SF3">
        <property type="entry name" value="FLUG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11917">
        <property type="entry name" value="DUF3435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="585" mass="67458" checksum="2A8344B5838D1CB9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWW7</accession>
    <name>W6YWW7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_109910</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NodC/HAS family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964209">
        <property type="protein sequence ID" value="EUC40014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693472.1">
        <property type="nucleotide sequence ID" value="XM_007695282.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6YWW7"/>
    <dbReference type="GeneID" id="19119517"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109910"/>
    <dbReference type="eggNOG" id="KOG2571">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_532249_0_0_1"/>
    <dbReference type="OrthoDB" id="9876900at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050501">
        <property type="term" value="F:hyaluronan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085029">
        <property type="term" value="P:extracellular matrix assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030213">
        <property type="term" value="P:hyaluronan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22913">
        <property type="entry name" value="HYALURONAN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22913:SF12">
        <property type="entry name" value="MANNURONAN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="9">
        <location>
            <begin position="80"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC40014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="517" mass="57959" checksum="58126F70A7457F19" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX61</accession>
    <name>W6YX61_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_104320</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964072">
        <property type="protein sequence ID" value="EUC42130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691362.1">
        <property type="nucleotide sequence ID" value="XM_007693172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX61"/>
    <dbReference type="STRING" id="930090.W6YX61"/>
    <dbReference type="GeneID" id="19118488"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104320"/>
    <dbReference type="eggNOG" id="KOG3200">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059836_0_0_1"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032862">
        <property type="entry name" value="ALKBH6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="9">
        <location>
            <begin position="100"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="152"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="288" mass="31159" checksum="385BA6972169CF55" modified="2014-04-16" version="1">MPGSEYSNAKQNVEAFRIAGLPPDFYYIPNFISVEEETSILQKIPAQRWTYLSHRRLQAVPSTLTKNNTLLASPLPIYLTTPIIDRFRDLGIFDHTPHEQPNHVLVNEYKPGQGIMPHEDGDAYAPVVATVSLGAPICLDILPKPSASASASAADDADVTTSNHAQESHDEAKSLSPATPTPITPNIMITTRTLPTRIFQEPRSLLVTTGSAYRHVMHGIAECETDEGMCEASVANWDLLGDKAMLEANGGVSTRGVRISLTYRDVLKVSTAASKVLGGLGGSRRRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY66</accession>
    <name>W6YY66_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_108646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964159">
        <property type="protein sequence ID" value="EUC40504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692963.1">
        <property type="nucleotide sequence ID" value="XM_007694773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY66"/>
    <dbReference type="GeneID" id="19119282"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108646"/>
    <dbReference type="eggNOG" id="ENOG502QTM1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030671_5_1_1"/>
    <dbReference type="OrthoDB" id="3683765at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="17484" checksum="2954F558539F6312" modified="2014-04-16" version="1">MLFDSLMSAAKAQGLSISDFREGDVLFVRSGYVQQYEAMSPERREKLDELYQREKPENIGLEPSKELLEFLWNIRFAAVAGDSRSFEKWPCTALQWHLHEWLLAGWGMPIGELFDLEDLSATCNELGRYTFFISSEPLNVPGGVASPPNALAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZP3</accession>
    <name>W6YZP3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_97337</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688699.1">
        <property type="nucleotide sequence ID" value="XM_007690509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZP3"/>
    <dbReference type="STRING" id="930090.W6YZP3"/>
    <dbReference type="GeneID" id="19129037"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97337"/>
    <dbReference type="eggNOG" id="KOG1209">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_1"/>
    <dbReference type="OrthoDB" id="2102561at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000140">
        <property type="term" value="F:acylglycerone-phosphate reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000261">
        <property type="entry name" value="NADPH-dependent 1-acyldihydroxyacetone phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="30612" checksum="A72749D753BCFF24" modified="2014-04-16" version="1">MATRQKTVLITGCTPGGIGHELALEFLRRGFQVFGTVRSEEAKKTLLSEGVIAVTLEVTSDASIQALHDEICERVGGKLDVLVNNVGISHTVPVLDLKIEDMRRVFEINVFSCIRLVQAFAPLLIEAKGKIANIGSVAGIVPYVFGGCYNASKAALHSYTDALRLEMAPFGVQVVLVVTAGVKSRISDVKKRLPPNSLYMPIEEDYLFRQGNSQRTAMPTETYARKVVSDLLEPTSKAWLWRGHQSSLVKWLSWLLPRGFWDLYFSRKFGLGKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZQ1</accession>
    <name>W6YZQ1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964041">
        <property type="protein sequence ID" value="EUC43068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690425.1">
        <property type="nucleotide sequence ID" value="XM_007692235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZQ1"/>
    <dbReference type="GeneID" id="19121310"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28437"/>
    <dbReference type="eggNOG" id="ENOG502S1RX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1360200_0_0_1"/>
    <dbReference type="OrthoDB" id="5339776at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025040">
        <property type="entry name" value="DUF3984"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13136">
        <property type="entry name" value="DUF3984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="201" mass="22090" checksum="8490AAF71401D5F3" modified="2014-04-16" version="1">MGSRVPSARPSRRGSRVGSRVDLMTGLGIKTAIEPEERFIEPDFIEADEDSDGDEEEVARLARERGFGLGGWMDRLIGWSLFAVDEDREGSSDSEDEDDEEGGDAREGKGLSGKDLKLDDLTKEELKLRREVEAKRRKMEREAIIAAAAVKSQHGEHEVGSRPSTAGEGEGSEEQSRRVNEEAGGWQDAAWLLSVASKALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZY6</accession>
    <name>W6YZY6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase B12 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_101635</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB3 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964038">
        <property type="protein sequence ID" value="EUC43158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690346.1">
        <property type="nucleotide sequence ID" value="XM_007692156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZY6"/>
    <dbReference type="STRING" id="930090.W6YZY6"/>
    <dbReference type="GeneID" id="19117897"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101635"/>
    <dbReference type="eggNOG" id="ENOG502SBXP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145518_1_0_1"/>
    <dbReference type="OrthoDB" id="521512at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012576">
        <property type="entry name" value="NDUFB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08122">
        <property type="entry name" value="NDUF_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC43158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9010" checksum="6DA2698F0B76E488" modified="2014-04-16" version="1">MAPRPSITGFDPKKFAAASANGTKGDPWARYEQWRYTGPFTRFNRFKGSFPGLGIATVAFAGYVVAEQLFFQDKGHHDDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z046</accession>
    <name>W6Z046_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_101379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690283.1">
        <property type="nucleotide sequence ID" value="XM_007692093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z046"/>
    <dbReference type="GeneID" id="19117863"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101379"/>
    <dbReference type="HOGENOM" id="CLU_174165_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="83" mass="8702" checksum="46F58038671271CB" modified="2014-04-16" version="1" fragment="single">PVCLPVCPPPTFVFTSSPPPLPPPHPSSSSSSSSSTRPGTPVVSPGQTDIQRQLPSGLQRLPEAMRWTRPMAAAAPARAYPIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2A9</accession>
    <name>W6Z2A9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_99755</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689664.1">
        <property type="nucleotide sequence ID" value="XM_007691474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2A9"/>
    <dbReference type="STRING" id="930090.W6Z2A9"/>
    <dbReference type="GeneID" id="19129527"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99755"/>
    <dbReference type="eggNOG" id="KOG1304">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009646_3_2_1"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF332">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="459"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="562"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="200"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="162"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="589" mass="65242" checksum="36B69137AEED3CD9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z351</accession>
    <name>W6Z351_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_104441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691387.1">
        <property type="nucleotide sequence ID" value="XM_007693197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z351"/>
    <dbReference type="GeneID" id="19118503"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104441"/>
    <dbReference type="HOGENOM" id="CLU_185444_0_0_1"/>
    <dbReference type="OrthoDB" id="10334605at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="72" mass="8120" checksum="D5582DBC95542F31" modified="2014-04-16" version="1" fragment="single">RGGRDEIHRARISHIYLRLPTCVLSRGEGELDHWVYGTARQPIARTTGCPDRVSGGMVNTSHGKPIAFLRWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3B6</accession>
    <name>W6Z3B6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Ras-related protein RSR1</fullName>
            <ecNumber evidence="3">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_37929</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="3"/>
    <dbReference type="EMBL" id="KI964009">
        <property type="protein sequence ID" value="EUC44203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689272.1">
        <property type="nucleotide sequence ID" value="XM_007691082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3B6"/>
    <dbReference type="STRING" id="930090.W6Z3B6"/>
    <dbReference type="GeneID" id="19123355"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37929"/>
    <dbReference type="eggNOG" id="KOG0395">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_9_0_1"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000131">
        <property type="term" value="C:incipient cellular bud site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007120">
        <property type="term" value="P:axial cellular bud site selection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007121">
        <property type="term" value="P:bipolar cellular bud site selection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000755">
        <property type="term" value="P:cytogamy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045184">
        <property type="term" value="P:establishment of protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032507">
        <property type="term" value="P:maintenance of protein location in cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035025">
        <property type="term" value="P:positive regulation of Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000114">
        <property type="term" value="P:regulation of establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000631">
        <property type="entry name" value="Ras small monomeric GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020100">
        <property type="entry name" value="Glc-repressible_Grg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11034">
        <property type="entry name" value="Grg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0636">Prenylation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="230"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="186"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC44203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="281" mass="31309" checksum="AF6FF9F383DA5B7C" modified="2014-04-16" version="1">MSQREYHIVVLGSGGVGKSCLTAQFVQNVWIESYDPTIEDSYRKVLEVDGRHVILEILDTAGTEQFKLYMKTGQGFLLVFSITSESSFWELAELREQIRRIKEDSNVPMVLIGNKSDLEDDRAVPRPRAFAISREWNVPYFETSARRRANVDEAFVDLCRQIIRKDQNERSRMAPPDSPRPGGPRNRTHTGRPKRKAHRPHSQGIVGQAVNSVKNAANYVSETIQGNAAEANKEANKQQAKGNVPGQDSLTDRASGALNAASDSINQKKHEGAADANKHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4F0</accession>
    <name>W6Z4F0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PrpF protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_76278</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpF family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964059">
        <property type="protein sequence ID" value="EUC42494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690981.1">
        <property type="nucleotide sequence ID" value="XM_007692791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4F0"/>
    <dbReference type="GeneID" id="19125340"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_76278"/>
    <dbReference type="eggNOG" id="ENOG502QSUX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026443_1_0_1"/>
    <dbReference type="OrthoDB" id="10267539at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007400">
        <property type="entry name" value="PrpF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709">
        <property type="entry name" value="ACONITATE ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709:SF2">
        <property type="entry name" value="DUF453 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G00360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04303">
        <property type="entry name" value="PrpF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="478"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC42494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="564" mass="60876" checksum="A1B7DF8B79402CD0" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z599</accession>
    <name>W6Z599_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_96815</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688549.1">
        <property type="nucleotide sequence ID" value="XM_007690359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z599"/>
    <dbReference type="STRING" id="930090.W6Z599"/>
    <dbReference type="GeneID" id="19128925"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96815"/>
    <dbReference type="eggNOG" id="KOG3996">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048602_1_0_1"/>
    <dbReference type="OrthoDB" id="4243at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF0">
        <property type="entry name" value="HOLOCYTOCHROME C-TYPE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="51"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC44933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="270" mass="30001" checksum="84454DE8BBAA2025" modified="2014-04-16" version="1">MSSKDDPAAACPVDHKTREAWLAQARAQNANAPPNPHHTPIPTPAAPPATLPRSQPQSVVQQSCDSSSLDQSTSSPPPTSTGLLSQIRLGTDREVSTIPRALPDTPSQRPANNERDTGADKTTGNWIYPSEQMFFDAMRRKSYDPSAPDMRTIVPIHNAVNERAWHEIKRWEAGRGSEACGGPKLASFSGLSTSLTPRARWKSLMGYQPPFDRHDWVVDRCGTKIEYVIDFYAGRDEGKVGKALNFYLDVRPKLNSWEGVKTRVMRFWGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5A8</accession>
    <name>W6Z5A8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_25151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686550.1">
        <property type="nucleotide sequence ID" value="XM_007688360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5A8"/>
    <dbReference type="STRING" id="930090.W6Z5A8"/>
    <dbReference type="GeneID" id="19120713"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25151"/>
    <dbReference type="eggNOG" id="KOG1572">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066297_0_0_1"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052840">
        <property type="term" value="F:inositol diphosphate tetrakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000035">
        <property type="entry name" value="Tyrosine phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF48">
        <property type="entry name" value="INOSITOL PHOSPHATASE SIW14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="31950" checksum="0534CA2F6CE7989A" modified="2014-04-16" version="1">MSISDGDGSALAPALGLRHYRDQNDEDNVYDRIREFVRSLGLSASDGLIYHATENTHEDLRDVLNPRDHECSSNCTADSHGTITPTLSIHSSPERLQPLVPPINYGAVLPGCIYRSGYPQEKNYGFIKDVGIKTILTLVPEPLTPEYQTFMKDAGIQHFHVHIRANKGEVRVESCEMARALRLIMDRSNHPILVHCNKGKHRTGCTIACFRRVLGLDPDVIREEYHTYAGAKARFLDEVFFENFDINLVMWVARQQGWVTPEMDIAPPTPPASITSSVTVKAVALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5C2</accession>
    <name>W6Z5C2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_7724</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">ATCC 44560</strain>
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        <cofactor evidence="1">
            <name>Fe(2+)</name>
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        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
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        <property type="protein sequence ID" value="EUC42764.1"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000005">
        <property type="entry name" value="TfdA family taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AtsK-like"/>
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        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
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    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
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    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="46"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="360" mass="39725" checksum="ED287FF7B08C4D60" modified="2014-04-16" version="1">MPSAEHVNAEDEYAAGGTRIFGGNATARSRLLEPLVYSGSLDSYKYQDLTPVIGREFEGLQVTDLLQASDAVIKDLAVTVSQRGVVFLRNQDVTPNQMRDLMLRLTELSGCPSSSGLHVHPLTEEGSELGDQISVISSEKQKKGGGLTHQLSDVSRLASAGWHSDITFEPVPSDYAMLKIHTLPATGGDTLWASGYEIYDRLSPAMRTFLEGLTATHDAKFFLDEAERLGNPLRKGVRGNPLNYGDALTAVHPVIRTNPVTGWKSVYVNKGFTKRINGITKDESDLLLPYLFNLVTQNHDAQVRFKWNKNDLAIWDNRSTWHCATYDYVEARAGDRVASLGEAPYLDLGSRGRREALEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5L0</accession>
    <name>W6Z5L0_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">DUF747-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_96674</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAPT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963992">
        <property type="protein sequence ID" value="EUC45058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007690263.1"/>
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    <dbReference type="STRING" id="930090.W6Z5L0"/>
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    <dbReference type="eggNOG" id="KOG2490">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="5376140at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008010">
        <property type="entry name" value="Tatp1"/>
    </dbReference>
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        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317:SF4">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05346">
        <property type="entry name" value="DUF747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="847"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="410"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="76"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="166"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="425"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="457"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="963" mass="108842" checksum="28BF95240ED5F3DF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6E5</accession>
    <name>W6Z6E5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GPR1/FUN34/YaaH-class plasma membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_101675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690373.1">
        <property type="nucleotide sequence ID" value="XM_007692183.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19117909"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101675"/>
    <dbReference type="eggNOG" id="ENOG502S179">
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    <dbReference type="HOGENOM" id="CLU_051062_4_0_1"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="34917" checksum="EB9BACE5261B917B" modified="2014-04-16" version="1">MDSPNGAHLSPTRDAETLSAGSTARNESTARTMDVNNCLEKDFSQPNGYGNGFPGHLNLDASVDSNTALHHIRTAGSISISPELFEKLYLSPPNKVKGELRKTFGNPTPIAIIGFLLSLFPLSMTLMGWRGAGGTGAANIGWYYFAGGLLMVLGGLGEWILGNTFPFVVFCSFGAFWLGFGATLQPFYNAYGAYANPSVQGSTGLESVGFNVGIAYFQIAMAILCLIFLICSIRTNLVFFMIFFSLTPAFGLLAGSYFQAANGRASLAKKLAEAGGAFCFVACLCGWYIFFAIMLASVDFPFNIPIVDLSSVVKGASEKRKVEHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6U6</accession>
    <name>W6Z6U6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_90040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686022.1">
        <property type="nucleotide sequence ID" value="XM_007687832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6U6"/>
    <dbReference type="GeneID" id="19127601"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90040"/>
    <dbReference type="eggNOG" id="ENOG502SHAY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_4_1"/>
    <dbReference type="OrthoDB" id="3897607at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF31">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="28"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="355" mass="38840" checksum="A0CE8AC04067705B" modified="2014-04-16" version="1">MTYFEDKAPNLAASVIALATIAYITFGLRVYTRLHNQAWGLDDWSMTLATIPFTGLTISCIGGAFSGVGIHDNKLSPSDKIKGMQFFFFFEVFYCAAIIPIKLSISFMLIRVASRRRKYIYSLYAVSAMFVVMNLIALLYIIFQCAPVSYAWDQSTPGGKCNPAQTLADIYYATTAINIATDWFCALLPIPLLWNVQLNRNAKLSVGVILGLGALASLSACIRLIYTVNLTSSTDYLHGVADVILWGYAENGVGMLVGCVATLRPLLQRVLKLGSSGSSATPHQTPGASYAKRPTVKSHLTGRDEEWVALEDGQMVNMVRGQGSIGSEEFILPSKDYRGIHVTSTVEQRTSSLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z803</accession>
    <name>W6Z803_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964243">
        <property type="protein sequence ID" value="EUC39821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693663.1">
        <property type="nucleotide sequence ID" value="XM_007695473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z803"/>
    <dbReference type="GeneID" id="19119605"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110473"/>
    <dbReference type="HOGENOM" id="CLU_1975718_0_0_1"/>
    <dbReference type="OrthoDB" id="10543019at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="127" mass="13638" checksum="58F4EF623C1C7527" modified="2014-04-16" version="1" fragment="single">FMSTAHDDDDADDDATAAASAAAKDARLVPTQTPTKHYCVFHPHPHPHNHHPCPPCSVPSRALSTSVVELNIEQGEAGCHDCLGSALISTSSYIPPCVSSQERNPFSAALAAFARHESRLALRLFMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z805</accession>
    <name>W6Z805_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_94185</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687591.1">
        <property type="nucleotide sequence ID" value="XM_007689401.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z805"/>
    <dbReference type="GeneID" id="19128405"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94185"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000092_2_0_1"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010106">
        <property type="term" value="P:cellular response to iron ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031169">
        <property type="term" value="P:ferrichrome biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd19542">
        <property type="entry name" value="CT_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000015">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000018">
        <property type="entry name" value="Nonribosomal siderophore peptide synthase SidC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000033">
        <property type="entry name" value="Nonribosomal siderophore peptide synthase SidC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000024">
        <property type="entry name" value="Nonribosomal siderophore peptide synthase SidC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003417">
        <property type="entry name" value="PRK04813.1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="1609"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="2667"/>
            <end position="2740"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="3743"/>
            <end position="3820"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="4296"/>
            <end position="4372"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="4852"/>
            <end position="4928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="4837"/>
            <end position="4858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="5404" mass="601120" checksum="49FD5904691756B3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z810</accession>
    <name>W6Z810_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687576.1">
        <property type="nucleotide sequence ID" value="XM_007689386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z810"/>
    <dbReference type="GeneID" id="19123024"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36420"/>
    <dbReference type="eggNOG" id="ENOG502SPB4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045435_2_1_1"/>
    <dbReference type="OrthoDB" id="5332316at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="442" mass="49909" checksum="008ABD7E3AE43977" modified="2014-04-16" version="1">MISSTNLRVDSKDGSHEAARAEEDPEAKQDVSFDDSSQSLPPSEEVSEQSLLEELFPEAHSAPPPRPTEKSRDQYPRLELPKSIIPELVGGPRKVNKGETEPFQQHREQIAVLQLTNCSTGLTEADFRRIIPKGKHLEGWRRDSDFYKVIPGRDPLSLERLPFYYLLFKNTKAALAYQKNASRLHKLSARYQPSSILSAIPPPKGFLEDGEDIGAAVASYNLLPKDHAMSLNVLMQPYNPALRLLIERGGYQPIAPGVDEKGNRIWRVLLHIEGYEPSASDIYIAVCTDAYRQGSLVPLRNESQSSIHRLRDMINLKMSSKLVSSSRPRAYGTFDHSDSPLVNAMSSSSSSSPLPSSMEMAYDDPEIQSMMGSADEDRPAAQMHQEVMNRVYNRWVLDFEDEHSARRWCLRWHRTVFPEPSGGDSVWKDSEEVRMCNAEVLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z833</accession>
    <name>W6Z833_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="3">FBP aldolase</shortName>
            <ecNumber evidence="3">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_94048</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2 3">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="3"/>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687523.1">
        <property type="nucleotide sequence ID" value="XM_007689333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z833"/>
    <dbReference type="STRING" id="930090.W6Z833"/>
    <dbReference type="GeneID" id="19128378"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94048"/>
    <dbReference type="eggNOG" id="KOG4153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040088_4_0_1"/>
    <dbReference type="OrthoDB" id="2558351at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050246">
        <property type="entry name" value="Class_II_FBP_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304:SF0">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC45933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="288" mass="31180" checksum="9A43E9B9E52C7DED" modified="2014-04-16" version="1">MPVSKENRTLAILSAAEAGNYGVMAAIAYNLEQLTALVRAAEAKRSPLIIQLFPSTLKQLPLLAHAAAHAVKTATVPLSLHIDHAQDVEHIRDIIETLPVDSVMVDMSHYDESENLEKTGILTKACHDKGIAVEAESGRIEGGEDGIADTGDLEALFTSPEDVDNFINAGIDILAPSIGNIHGDYGPAGPKEGQLHYDRLESINKQVNKRVHVALHGTNDFPPEVMQRCIRSGAIKLNVNKLLLEAGNQVLRKNASTTLLAKLIDMQMEAIQKETERWMDICGSSGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8Y4</accession>
    <name>W6Z8Y4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">propanoyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Propanoyl-CoA C-acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_35853</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.1.176" evidence="2"/>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686964.1">
        <property type="nucleotide sequence ID" value="XM_007688774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8Y4"/>
    <dbReference type="STRING" id="930090.W6Z8Y4"/>
    <dbReference type="GeneID" id="19122886"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35853"/>
    <dbReference type="eggNOG" id="KOG1406">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035425_0_1_1"/>
    <dbReference type="OrthoDB" id="542135at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00829">
        <property type="entry name" value="SCP-x_thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000016">
        <property type="entry name" value="Non-specific lipid-transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055140">
        <property type="entry name" value="Thiolase_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006102">
        <property type="entry name" value="PRK08256.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870:SF1">
        <property type="entry name" value="NON-SPECIFIC LIPID-TRANSFER PROTEIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22691">
        <property type="entry name" value="Thiolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="9">
        <location>
            <begin position="25"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="10">
        <location>
            <begin position="263"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC46490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="459" mass="49781" checksum="4F61AB9EC58CE52B" modified="2014-04-16" version="1">MAPKNETPVYVLGVGLTKFIKPRQTRAYPEMGYEAGVKAMLDAQINYDDVETGVACYCYGDTTSGQRIFYQFGMTGIPIYNTNNACATGSTGLHLARSLIKNGAIDCALVIGFEQMQPGSIKSVYSDRPSPMGLSMRMMADTRGITNSPPNAQYFANAGLEYMEKYGAEARDFAEIARISHEHSSRNPYAQFRDVYTLEQIEKSPMIHFPLTKLQCSPTSDGAGAAVLVSQKFLDARPHLKSQAILIAGQALMTDSPQLYSKSSMDLVGYDMTKRAAQAALKEAGVSPKDVKVAELHDCFSANELILLEGLGFSEPGKAHMMVRNGDITYGGKGPIINPSGGLISKGHPLGATGLAQCAELTWQLRGWANNRLAEGADVALQHNLGLGGAVVINVYKRADESKNVKMSDEDVKRVSQFAYNPAVEARYVTKEEGDKVRSKAAASEYALGDTLEKIKSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z930</accession>
    <name>W6Z930_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Threonine/serine exporter-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_38035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964012">
        <property type="protein sequence ID" value="EUC44064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689400.1">
        <property type="nucleotide sequence ID" value="XM_007691210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z930"/>
    <dbReference type="GeneID" id="19123378"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38035"/>
    <dbReference type="eggNOG" id="ENOG502QPMM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007078_2_1_1"/>
    <dbReference type="OrthoDB" id="413008at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="516"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="541"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="596"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="633"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="675"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="815"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="885"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="4">
        <location>
            <begin position="410"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="273"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="916" mass="100875" checksum="14A7AF6A50FB7D2A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9S2</accession>
    <name>W6Z9S2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="6">PPIase</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_33980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684926.1">
        <property type="nucleotide sequence ID" value="XM_007686736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9S2"/>
    <dbReference type="STRING" id="930090.W6Z9S2"/>
    <dbReference type="GeneID" id="19122453"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33980"/>
    <dbReference type="eggNOG" id="KOG0881">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_3_1"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000008">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="8"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC48497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="166" mass="18227" checksum="D6CA5F9B08B87E86" modified="2014-04-16" version="1">MATDVALDTTIGTVVVELYNDHAPKTCKNFLTLAQRGYFNGLIFHRIIPNFMIQGGDPTGTGRGGESIYGEKFEDEISPQLKHTGAGILSMANSGPNTNGSQFFITLAPTPWLDGKHTIFGRVKSGMQVVKKLGLVKTDKEDRPVEEVKIVRAYLPDDNAQALQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9X1</accession>
    <name>W6Z9X1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_91997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686736.1">
        <property type="nucleotide sequence ID" value="XM_007688546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9X1"/>
    <dbReference type="GeneID" id="19127986"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91997"/>
    <dbReference type="HOGENOM" id="CLU_449897_0_0_1"/>
    <dbReference type="OrthoDB" id="3944567at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="563" mass="61814" checksum="840AEE5B09410981" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAJ4</accession>
    <name>W6ZAJ4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_97907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688954.1">
        <property type="nucleotide sequence ID" value="XM_007690764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAJ4"/>
    <dbReference type="GeneID" id="19129146"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97907"/>
    <dbReference type="eggNOG" id="ENOG502SSNK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104465_1_0_1"/>
    <dbReference type="OrthoDB" id="5426872at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="199" mass="21429" checksum="AA7B243F0B020F95" modified="2014-04-16" version="1">MLLEAPPPRRQVSSAPVSLSAASAVLEKYLQNSETHAHLHPDALITPDGVTFNAKGGAVGNLLMHHLRRVAAGLRGEYLEPDTTLEAQAEALDAAAADGEGSKNTGVEQEWQDVATYQAEQGGIEIGDVGNRTNVVQEGGQEPPVQTNDTKKRKKDQAHGQTQQSPPDGQVDKDARKKAKKERDLQRKRDNAAKAKKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAS3</accession>
    <name>W6ZAS3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_86099</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684660.1">
        <property type="nucleotide sequence ID" value="XM_007686470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAS3"/>
    <dbReference type="GeneID" id="19126797"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86099"/>
    <dbReference type="eggNOG" id="ENOG502QUGJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001743_0_0_1"/>
    <dbReference type="OrthoDB" id="3199820at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000183">
        <property type="term" value="P:rDNA heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ams2-SPT21_N"/>
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        <property type="entry name" value="Spt21/Ams2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
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        <property type="entry name" value="Znf_NHR/GATA"/>
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        <property type="entry name" value="PROTEIN SPT21"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PROTEIN SPT21"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Ams2-SPT21_N"/>
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    </dbReference>
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        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
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    </dbReference>
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        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="949"/>
            <end position="979"/>
        </location>
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        </location>
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        </location>
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            <end position="495"/>
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            <end position="674"/>
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            <begin position="1234"/>
            <end position="1275"/>
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        <location>
            <begin position="1"/>
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            <begin position="218"/>
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        <location>
            <begin position="243"/>
            <end position="282"/>
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    </feature>
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        <location>
            <begin position="333"/>
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    </feature>
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        <location>
            <begin position="459"/>
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        </location>
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        <location>
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        <location>
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            <end position="1045"/>
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            <end position="1081"/>
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        <location>
            <begin position="1235"/>
            <end position="1246"/>
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    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1275" mass="138926" checksum="FD28C9B0EB620782" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB69</accession>
    <name>W6ZB69_COCMI</name>
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        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_90684</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HEXOSE TRANSPORTER"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
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            <begin position="20"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="173"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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            <end position="206"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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            <end position="428"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="440"/>
            <end position="459"/>
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    </feature>
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        <location>
            <begin position="21"/>
            <end position="462"/>
        </location>
    </feature>
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        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
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        <location>
            <begin position="512"/>
            <end position="522"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC47190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="533" mass="58398" checksum="5AC2568E9F92AB97" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB91</accession>
    <name>W6ZB91_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="6" type="ORF">COCMIDRAFT_107364</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964126">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694293.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19119030"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107364"/>
    <dbReference type="eggNOG" id="KOG0143">
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    <dbReference type="HOGENOM" id="CLU_010119_1_1_1"/>
    <dbReference type="OrthoDB" id="627829at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050295">
        <property type="entry name" value="Plant_2OG-oxidoreductases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47991">
        <property type="entry name" value="OXOGLUTARATE/IRON-DEPENDENT DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="5">
        <location>
            <begin position="185"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="386" mass="43524" checksum="E1FF295FB74CCAA5" modified="2014-04-16" version="1">MSPPRSPLPLQPFSQIPILPLSAALAPNTKPAFLADLRSALLHVGFLYLSETGLPEELVQAVISECRGFFENLPVEEKEKIEMKNEKSFLGWSRLDNETTAFNPDHREQLDLSTPHPIPGPEAPIYHNLLAPNQWPSPQHLPNFRPVYEEYIQRMARISTLFTSLIAEAIDLPATAFDKFFDRDQQHKLKIVKYPEVDVPDLPQGASEMDRKKWEIKRQGVGPHKDSMLTSYLLQASNQLGLQAQNAKGEWIDCPPIPGTLVVAIGQGMEALTDGVCASTTHRVLSPRKGEGARYSVPFFQGVSYDAQFEAMDVPEEVLKLRDEARKQRRDDVEFTFVKGRWGHLGEATLMNRIKSHPDVGERWYPEELRRIRAQQAAVSADKPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBF0</accession>
    <name>W6ZBF0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">MICOS complex subunit MIC60</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Mitofilin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_107164</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 13">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion inner membrane</location>
            <topology evidence="1 13">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MICOS complex subunit Mic60 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964122">
        <property type="protein sequence ID" value="EUC41056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692418.1">
        <property type="nucleotide sequence ID" value="XM_007694228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBF0"/>
    <dbReference type="STRING" id="930090.W6ZBF0"/>
    <dbReference type="GeneID" id="19118993"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107164"/>
    <dbReference type="eggNOG" id="KOG1854">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008024_1_2_1"/>
    <dbReference type="OrthoDB" id="10261039at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019133">
        <property type="entry name" value="MIC60"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415:SF7">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415">
        <property type="entry name" value="MITOFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09731">
        <property type="entry name" value="Mitofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="35"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="182"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="317"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC41056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="639" mass="69562" checksum="D0DEFEEA5EA63947" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBF7</accession>
    <name>W6ZBF7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_90884</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686351.1">
        <property type="nucleotide sequence ID" value="XM_007688161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBF7"/>
    <dbReference type="STRING" id="930090.W6ZBF7"/>
    <dbReference type="GeneID" id="19127775"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90884"/>
    <dbReference type="eggNOG" id="KOG0894">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041481_3_0_1"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180027">
        <property type="term" value="P:inner nuclear membrane-associated protein degradation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000058">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="5"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="277" mass="30326" checksum="7C535D3AD17091EE" modified="2014-04-16" version="1">MATPAATKRLTREYATISKSPPPYITAHPSDRNILEWHYIITGPPDTPYEGGQYWGTLNFPPDYPFAPPAIRMHTPSGRFQPSSRLCLSISDFHPKSFNPAWEVSTILTGLLSFMTSEEMTTGSVRASDAERKLFAQRTRWWNSTGGGTKAIGSGNAAGGQNGNIRAGDGGAKFRHEWPDVDEENLRWMKEKRIDPATGLPRPAPSPAQHPPCSPDVSGLRRRPGTSATVVQDAAQIARDAGQSWLSRNKWRIILGTMMLYIMVARVLGDGAIASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC82</accession>
    <name>W6ZC82_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_22982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684064.1">
        <property type="nucleotide sequence ID" value="XM_007685874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC82"/>
    <dbReference type="GeneID" id="19120357"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22982"/>
    <dbReference type="HOGENOM" id="CLU_1488756_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="181" mass="19310" checksum="A6B6A11B31E17FED" modified="2014-04-16" version="1">MAAEAMYIRSKQAEPWLDETHKSLRRPAVTGGREGQRLHQHLHQHLHLHLDGVDYLLLDAVGGAGEGEKVKPTTGLTVEHVVLQHDTDSRSFPWASRWREERSGFDTLFGAAGGVQGMGEGFCACQGLRRLLKQEEAACHLGPWAAMARPEAPHDAGTDDASAAAASAAAAAAGNAAMTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCB3</accession>
    <name>W6ZCB3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_89663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685860.1">
        <property type="nucleotide sequence ID" value="XM_007687670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCB3"/>
    <dbReference type="GeneID" id="19127520"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89663"/>
    <dbReference type="eggNOG" id="ENOG502SHF3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005049_1_2_1"/>
    <dbReference type="OrthoDB" id="3057168at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF16">
        <property type="entry name" value="DUF2235 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="1">
        <location>
            <begin position="11"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="582" mass="66306" checksum="D3D63BC83A48B5A2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCB6</accession>
    <name>W6ZCB6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_90073</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686015.1">
        <property type="nucleotide sequence ID" value="XM_007687825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCB6"/>
    <dbReference type="STRING" id="930090.W6ZCB6"/>
    <dbReference type="GeneID" id="19127606"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90073"/>
    <dbReference type="eggNOG" id="KOG1532">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037460_1_2_1"/>
    <dbReference type="OrthoDB" id="243313at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17870">
        <property type="entry name" value="GPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030230">
        <property type="entry name" value="Gpn1/Npa3/XAB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF8">
        <property type="entry name" value="GPN-LOOP GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="395"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="441" mass="48748" checksum="1AB5DB19B63A521E" modified="2014-04-16" version="1">MSASKAPEGATPAAASNAPVSIVCVGMAGSGKTTFMQRLVSHLYTHPDPTKSEPSVSKTPPTPPYIINLDPAVHHVPFTPNIDIRDSVNYKEVMKQFNLGPNGGILTSLNLFSTKIDQIIGLLEKRTQPPPPQKEPEPSTVEFMTSGGKDKQAAPVQQAQVKHILVDTPGQIEVFVWSASGEILLSSLASTFPTVIAYIIDTPRTTSTSTFMSNMLYACSILYKTKLPMILVFNKTDAQDAQFAKDWMTDFEAFQTALRNEEEGGTFGGEGIGGGSGYMGSLLNSMSLVLEEFYKHLSVVGVSAMTGEGMDEFFKGVEEKKAEFERDYKPELERRRVEREQEKKASRQRELDKMMKDMKVGGAGTKPKPRPRKEEPQTVSDAEDSEDDAMAHDDLDYEDEMDSDDPESGIKERYRQAVQDRGLDQGEDHSFARYVNMAKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCF4</accession>
    <name>W6ZCF4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_5685</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688376.1">
        <property type="nucleotide sequence ID" value="XM_007690186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCF4"/>
    <dbReference type="STRING" id="930090.W6ZCF4"/>
    <dbReference type="GeneID" id="19124701"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5685"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
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    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886708" evidence="3">
        <location>
            <begin position="20"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="387"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC45109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="683" mass="74210" checksum="9A09260676862BD0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCL7</accession>
    <name>W6ZCL7_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_48071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10194" checksum="016935306CFE5A68" modified="2014-04-16" version="1" fragment="single">CNGERPQCSECAARDSQCQYKETETAQTKRKHQDLEELFELLKSLPYEDASETLARIRAGEEPRDIVETITHGNVLMQIATEIGGNKPSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD24</accession>
    <name>W6ZD24_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_42287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685765.1">
        <property type="nucleotide sequence ID" value="XM_007687575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD24"/>
    <dbReference type="STRING" id="930090.W6ZD24"/>
    <dbReference type="GeneID" id="19124170"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_42287"/>
    <dbReference type="HOGENOM" id="CLU_102622_1_0_1"/>
    <dbReference type="OrthoDB" id="2958217at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="63"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="149" mass="16223" checksum="B8BFDF11BE6E47F6" modified="2014-04-16" version="1" fragment="single">SAPTLNLFADWINKCVQNHKVCNTVPNARPPSRLLRINLAPAPEYGIPTLQLFHTSPTEQYTYVAVSHCWSYTQPLKTTAANLTAHLASVPSGSLSPVFRDAILLCICLGYDYIWIDSLCILQGDAVDFAAEAPHMGHVYAQAALVIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDT4</accession>
    <name>W6ZDT4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_82953</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683428.1">
        <property type="nucleotide sequence ID" value="XM_007685238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDT4"/>
    <dbReference type="STRING" id="930090.W6ZDT4"/>
    <dbReference type="GeneID" id="19126159"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82953"/>
    <dbReference type="eggNOG" id="ENOG502QV06">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035914_2_0_1"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889755" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="342" mass="38080" checksum="54FE1246738C1BA1" modified="2014-04-16" version="1">MVKLQVITSALSLASLAFAAALPAPHVSTCKKPAKRLEWRQMSTSQKHSYISAVLCLQKIPSISGFPYAKNRYDDFQAIHHDQGNYIHWVGFFLPWHRYFVWAYEQTLRNECGYKGAQPYWDYTLDADPQNLNSTRIYETDIFSPTLGFGGNGPRVIPTPEQNPLGVNNTGGGCIQDGPFVPKNFMLNFPGPEPQCLRRDFSPNLLNRGADPKVAENILSKDTYVAFDRALQGAKNFINPNIHAAGHFGVGGVFGQAGDVKNSPGEPLFWLHHASIDRLWWLWQQGNLATRNFEIGGNLVPEVYGNETEVTPKFEIQLGAVAGTVALAKLLDARGEVFCYSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE21</accession>
    <name>W6ZE21_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_87889</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685254.1">
        <property type="nucleotide sequence ID" value="XM_007687064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE21"/>
    <dbReference type="STRING" id="930090.W6ZE21"/>
    <dbReference type="GeneID" id="19127150"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87889"/>
    <dbReference type="eggNOG" id="KOG2764">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_2_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903189">
        <property type="term" value="P:glyoxal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03135">
        <property type="entry name" value="GATase1_DJ-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006287">
        <property type="entry name" value="DJ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01383">
        <property type="entry name" value="not_thiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF12">
        <property type="entry name" value="PARKINSON DISEASE PROTEIN 7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="3"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="197" mass="21252" checksum="B6551A0A0B43CEE4" modified="2014-04-16" version="1">MPKALILIADGSEEIEFVTPYDVLTRAGFEVKSAGISLQNEAYAHMSRNIRIVPDYANLNSVPLQPAHEHFDVLILPGGGPGSKTFCESDAVLKLIDGFQQAGKWVAAICAATTALVASTKKFDKDKKRVTSHPSVAEEIKVAGWQYSEDRLVVDGKVITSRGPGTAMLFALTIVEVISGKEKRDEIAGPMVLAEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE62</accession>
    <name>W6ZE62_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_87517</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685161.1">
        <property type="nucleotide sequence ID" value="XM_007686971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE62"/>
    <dbReference type="STRING" id="930090.W6ZE62"/>
    <dbReference type="GeneID" id="19127084"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87517"/>
    <dbReference type="eggNOG" id="ENOG502SP2V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057752_5_2_1"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="22"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="285" mass="31513" checksum="7BCB11CA2BBEE4D1" modified="2014-04-16" version="1">MDAPMIELKSALASLFQCGQYSDLTIVCGAKRYQVHRILLATRSTFFEGACRGGFREAESGVIDLSEDDAEAVEHMIHYFYHMDYLSKKPLSRRSSQRSNQPTSLRRKQTPSRKLTLDPSEDPLLALVAAAAPLTPPPNEPTFQNVDASAKLAATPMVDQILEDDDLESVESEPESEIQSAHLVAHAKVYAIAEKYGIAGLKALARSKFVDQINLHLASPEFPEACQEAYESTFHSDRGLRDVIIQAFRANPSLSLRPDVEMMVRETPGLAFELFRMASGLPVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE90</accession>
    <name>W6ZE90_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Caleosin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_34201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the caleosin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685144.1">
        <property type="nucleotide sequence ID" value="XM_007686954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE90"/>
    <dbReference type="STRING" id="930090.W6ZE90"/>
    <dbReference type="GeneID" id="19122507"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34201"/>
    <dbReference type="eggNOG" id="ENOG502QQD0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062049_0_0_1"/>
    <dbReference type="OrthoDB" id="640742at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007736">
        <property type="entry name" value="Caleosin-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31495:SF0">
        <property type="entry name" value="BINDING PROTEIN CALEOSIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G13750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31495">
        <property type="entry name" value="PEROXYGENASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05042">
        <property type="entry name" value="Caleosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="30115" checksum="13DBCFC3E1531C36" modified="2014-04-16" version="1">MFAKFNDNAGESGVPEDGVPVYAIREVPITAQRKPWFDVNDPKLPQPAVARANLAPSVDTPQGSTQDNWAEKHSHQTVLQQHCDFFDRDGDGILWPQDTYMGFYRLGLGVFFSAFAVLVIHINFSYPTSPGWLPDPYFRLFLKNVHRARHGSDTGTFDPEGRFIPAKFEEIFTKYAEGRDYLTVHGLKNTLMGQRDINDPIGWCGFIFEWTATYLMLWPEDGRMMKEDIRAVYDGSIFHRIADKRERRLHQQEQLKRQKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZED5</accession>
    <name>W6ZED5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein MON2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_1132</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MON2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683243.1">
        <property type="nucleotide sequence ID" value="XM_007685053.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZED5"/>
    <dbReference type="GeneID" id="19119797"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1132"/>
    <dbReference type="eggNOG" id="KOG1848">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001169_1_0_1"/>
    <dbReference type="OrthoDB" id="294853at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF333">
        <property type="entry name" value="PROTEIN MON2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="8">
        <location>
            <begin position="47"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HUS" evidence="6">
        <location>
            <begin position="142"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="7">
        <location>
            <begin position="935"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="420"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="7"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1617" mass="177576" checksum="5DCA03DD28FE4F17" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEJ1</accession>
    <name>W6ZEJ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_94153</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687524.1">
        <property type="nucleotide sequence ID" value="XM_007689334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEJ1"/>
    <dbReference type="STRING" id="930090.W6ZEJ1"/>
    <dbReference type="GeneID" id="19128400"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94153"/>
    <dbReference type="eggNOG" id="ENOG502SJ3K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008719_4_1_1"/>
    <dbReference type="OrthoDB" id="5319341at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="169"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC45934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="594" mass="66428" checksum="4E2C0E75C4D327ED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEQ2</accession>
    <name>W6ZEQ2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_23671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684913.1">
        <property type="nucleotide sequence ID" value="XM_007686723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEQ2"/>
    <dbReference type="GeneID" id="19120478"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23671"/>
    <dbReference type="eggNOG" id="ENOG502SR76">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143689_1_1_1"/>
    <dbReference type="OrthoDB" id="2787676at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="118" mass="13205" checksum="C34424754696A338" modified="2014-04-16" version="1">MEKCVNDLMAKAVDGNKWKMFSKVSVEIGSTVWPLNPRDQRRFGMRYVYDGEITSGDGVEYNKFQMLSNDGKVPAPINQWKENNGGPNPVMATAYLKKSGTKEDVEEGLKEGAKLIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF98</accession>
    <name>W6ZF98_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_86709</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684891.1">
        <property type="nucleotide sequence ID" value="XM_007686701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF98"/>
    <dbReference type="GeneID" id="19126913"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86709"/>
    <dbReference type="eggNOG" id="KOG0496">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005732_2_1_1"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000040">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889974" description="beta-galactosidase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase" evidence="10">
        <location>
            <begin position="380"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="985" mass="108036" checksum="C2FC8C83A70F420A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFK3</accession>
    <name>W6ZFK3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_60777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684790.1">
        <property type="nucleotide sequence ID" value="XM_007686600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFK3"/>
    <dbReference type="STRING" id="930090.W6ZFK3"/>
    <dbReference type="GeneID" id="19124824"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_60777"/>
    <dbReference type="eggNOG" id="ENOG502SZI1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065420_0_0_1"/>
    <dbReference type="OrthoDB" id="4364842at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="256" mass="29370" checksum="0A6A97BDB9708D28" modified="2014-04-16" version="1" fragment="single">MSTHTVCSDIILQGQSNWELWIFIVKRIAEAGDVWEYIDPNKPANPLQKPVQPTRPEPTIQQELLYHIKDKATVHDQIKTLQELFSPTTSDMEYRVQKDYEAAKVLHARRSNVEDWCNEFLTAYSRAKQLNLPEVHGFRAHKDLIRAIKQIDAAYAASASLDIFKAEEDWNTDRSKPIPHQSQLSTVLAEYLRYHRTTYSRKANIHGGAFGVTMNGQPSPYNNKKRSRDSENKPAKPCLCGDSHFWGQCPYIDTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFL8</accession>
    <name>W6ZFL8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_86262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684643.1">
        <property type="nucleotide sequence ID" value="XM_007686453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFL8"/>
    <dbReference type="GeneID" id="19126823"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86262"/>
    <dbReference type="eggNOG" id="ENOG502SU1E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095070_2_1_1"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2970">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="197" mass="22197" checksum="DDBCB163CF84EA1C" modified="2014-04-16" version="1">MAALWNLRIALLTGLAVTLLGAFYIYQSPSPLDFTVPHRTSGNGLPGLEVSLSPRSRDPPTLLVTVENNHSDTTYTVLKWNTPLDPYALDAGVFSIIDETSHREIEQAIIHITRKMPPPPNQLLTLAPGMREEIEILFNRPWMPERRPAKYRVGAEGVFKGAWAKHRDELTKDELYAFATSPFSGRRFVTNEVIMEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGA4</accession>
    <name>W6ZGA4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PEBP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_7914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964058">
        <property type="protein sequence ID" value="EUC42536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690939.1">
        <property type="nucleotide sequence ID" value="XM_007692749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGA4"/>
    <dbReference type="STRING" id="930090.W6ZGA4"/>
    <dbReference type="GeneID" id="19125433"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7914"/>
    <dbReference type="eggNOG" id="KOG3346">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043994_3_1_1"/>
    <dbReference type="OrthoDB" id="2506647at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030162">
        <property type="term" value="P:regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046578">
        <property type="term" value="P:regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF85">
        <property type="entry name" value="INHIBITOR (TFS1), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="21452" checksum="C11C42BC6B9BC49A" modified="2014-04-16" version="1">MAATSFVDALKSANLLPSSIIPDSFTPTIQLSVKFPSGLAPERGSLARVSQIAEQPVISISSMSDSPSSASTFAFMMIDPDAPTPDDPKFAYWRHWVITSIPSTVSPTDDITSNGKTLTQYLAPGPKDESGPHRYLFLLFEEKEGETLEKAEIGGEEFVERRSFRAEELVAKKGLKLVGVQWMRGVGDGWNGGKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGF5</accession>
    <name>W6ZGF5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase family 90 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_35817</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686898.1">
        <property type="nucleotide sequence ID" value="XM_007688708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGF5"/>
    <dbReference type="STRING" id="930090.W6ZGF5"/>
    <dbReference type="GeneID" id="19122877"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35817"/>
    <dbReference type="HOGENOM" id="CLU_005027_4_2_1"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="3">
        <location>
            <begin position="298"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="574" mass="65791" checksum="036B740FAAD57A11" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGI8</accession>
    <name>W6ZGI8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Luciferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_80502</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682603.1">
        <property type="nucleotide sequence ID" value="XM_007684413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGI8"/>
    <dbReference type="STRING" id="930090.W6ZGI8"/>
    <dbReference type="GeneID" id="19125681"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80502"/>
    <dbReference type="eggNOG" id="ENOG502S7YG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_1_2_1"/>
    <dbReference type="OrthoDB" id="2558704at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008726">
        <property type="term" value="F:alkanesulfonate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046306">
        <property type="term" value="P:alkanesulfonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01094">
        <property type="entry name" value="Alkanesulfonate_monoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024014">
        <property type="entry name" value="DMSO2_SphG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050172">
        <property type="entry name" value="SsuD_RutA_monooxygenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04021">
        <property type="entry name" value="LLM_DMSO2_sfnG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42847">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42847:SF4">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="6">
        <location>
            <begin position="64"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="422" mass="47514" checksum="9651B4E3DFD403CD" modified="2014-04-16" version="1">MSPSRKRQRTEVEGSSTNGTNGHANGTEDSFTPIKQLDINQDPDRVLFAYWVPNVSGGLVVSKIPQKTNWDLASNVRYARTAEEYGFEYALTQIRFTASYGADNQHESVSFSQALLHSTERLKLIAAILPGIWNPTVAAKQLASIDNYSNGRIAVNMVSGWNKGEFTAVGQWWLEHAERYRRTNEFIRALKGIWTADDKGFSFAGDFYQFHDYKLAPKPLQKPHPEIFQGGNSDDARHNGAEVSDWYFMNGNDLDGFREQIADVKARARKFGREDSVRFGVNGFVIIRDTEDEAIRVLKEIQGKADVEAVEAFRGAVQQAGASTANKKGMWANSSFEDLVQYNDGFKTKLIGTKEQIADRILLLKSLGVDLVLTAHLHYEEDIERFGKEVLPLVRKLESEGRGKDAEDEIRRTGHVYQKVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGP1</accession>
    <name>W6ZGP1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_33441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGP1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_33441"/>
    <dbReference type="eggNOG" id="ENOG502S06P">
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    </dbReference>
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    <dbReference type="OrthoDB" id="190201at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="356" mass="38990" checksum="B7E3DB928C67BC95" modified="2014-04-16" version="1">MLLTESTEPPVTTFDSVSPTQSKDSIFRPSMLYNVLPTVVSSRLPTIPSLRQSFGDVRSRTYYNKSDTVIELPQPVTPPPGYSTMPPSETVSPHKLSAALGEAEVDFADDVSEGQASSRAMPLVVPGAQETRSGVKWRYAGLGISLLQQAARESNASSGGLDEASATLIRQLYVHGITYLLRGLPADLTQEEKLSLQAALPQDLVESVSDSNTGALVRATPQSSDPAQGPPQNPTIIHRITAAFVLQTFLFLQFLLPYIRLFLSHAYRFERKHRITQRLINTSVATADEFGQKALKFSQVVCQMNDGMVIQTFNDLTMWWITGVTGGVQQGLAEGLRTIKAAEGQRHAEVEEEKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGU0</accession>
    <name>W6ZGU0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF427 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_79961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGU0"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_79961"/>
    <dbReference type="eggNOG" id="ENOG502S7EG">
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    </dbReference>
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    <dbReference type="OrthoDB" id="18996at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="entry name" value="Domain of unknown function (DUF427)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310:SF5">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF427" evidence="1">
        <location>
            <begin position="5"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="98" mass="11051" checksum="DE7C4E995723C96E" modified="2014-04-16" version="1">MPHATATVNGVLVAETDSYEVVDGNIYFPPSAIKESHFTPTSTKTHCPYKGEASYYTITTNKTEVKDAAWYYPEPLESMNKIKGYVAFYKRMADIKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH86</accession>
    <name>W6ZH86_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein phosphatase PP2A regulatory subunit A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_33233</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684081.1">
        <property type="nucleotide sequence ID" value="XM_007685891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZH86"/>
    <dbReference type="STRING" id="930090.W6ZH86"/>
    <dbReference type="GeneID" id="19122273"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33233"/>
    <dbReference type="eggNOG" id="KOG0211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015533_2_1_1"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005934">
        <property type="term" value="C:cellular bud tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090443">
        <property type="term" value="C:FAR/SIN/STRIPAK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110085">
        <property type="term" value="C:mitotic actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030952">
        <property type="term" value="P:establishment or maintenance of cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990813">
        <property type="term" value="P:meiotic centromeric cohesion protection in anaphase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031030">
        <property type="term" value="P:negative regulation of septation initiation signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000011">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="88"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase 2A Regulatory Subunit A helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="204"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="245"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="4">
        <location>
            <begin position="277"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="284"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="323"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="362"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase 2A Regulatory Subunit A helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="401"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="518"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="581"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="613" mass="68460" checksum="2D97D396BB75434C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHG4</accession>
    <name>W6ZHG4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_91647</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the anamorsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686669.1">
        <property type="nucleotide sequence ID" value="XM_007688479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHG4"/>
    <dbReference type="STRING" id="930090.W6ZHG4"/>
    <dbReference type="GeneID" id="19127922"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91647"/>
    <dbReference type="eggNOG" id="KOG4020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067152_1_0_1"/>
    <dbReference type="OrthoDB" id="311633at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11000">
        <property type="entry name" value="Fe-S cluster assembly protein Dre2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03115">
        <property type="entry name" value="Anamorsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007785">
        <property type="entry name" value="Anamorsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046408">
        <property type="entry name" value="CIAPIN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031838">
        <property type="entry name" value="Dre2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273:SF14">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05093">
        <property type="entry name" value="CIAPIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16803">
        <property type="entry name" value="DRE2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S cluster assembly protein Dre2 N-terminal" evidence="13">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Anamorsin C-terminal" evidence="12">
        <location>
            <begin position="228"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="139"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Fe-S binding site A" evidence="10">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Fe-S binding site B" evidence="10">
        <location>
            <begin position="294"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cx2C motif 1" evidence="10">
        <location>
            <begin position="294"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cx2C motif 2" evidence="10">
        <location>
            <begin position="305"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC46859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="331" mass="35012" checksum="05296AFBA8E34B2B" modified="2014-04-16" version="1">MAPRCLLIGTPSIAAHPEQLDKVYEIHDRKSTDLQMLDRIAAGLVNLPASTYDVVLLLADADGTTRESHKLLARDVMNKVVGALKVGGVLKSQAGPLQGSEKTEAILAGLTETADGMTKPEQEEAVSIPLKFGKKKAGAVNGTNGTNGTNGTNGTNGTNGTNGTVNPDGSVPLNLNGKRNQTEPAKPNGVGFVDFSDDLDDPIITGEDDDLIDEDEFITEADMARPVIQPPECQPKPGKRRRACKDCTCGMKEKLEAEDAARRASADKALNALKLDADDLAEVDFTVQGKVGSCGNCALGDAFRCDGCPYIGLPAFKPGEEVRLLNNDIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHG8</accession>
    <name>W6ZHG8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein SSH4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein ssh4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_84376</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SSH4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683992.1">
        <property type="nucleotide sequence ID" value="XM_007685802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHG8"/>
    <dbReference type="STRING" id="930090.W6ZHG8"/>
    <dbReference type="GeneID" id="19126454"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84376"/>
    <dbReference type="eggNOG" id="KOG1477">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016552_1_0_1"/>
    <dbReference type="OrthoDB" id="258495at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12910">
        <property type="entry name" value="SPRY_SSH4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.920:FF:000065">
        <property type="entry name" value="Ear1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035780">
        <property type="entry name" value="SPRY_Ssh4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0967">Endosome</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="18">
        <location>
            <begin position="128"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="384"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="384"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="454"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC49440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="527" mass="58017" checksum="A5B7F07183339395" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHK9</accession>
    <name>W6ZHK9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication licensing factor MCM2</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">DNA replication licensing factor mcm2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Minichromosome maintenance protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_131</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682065.1">
        <property type="nucleotide sequence ID" value="XM_007683875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHK9"/>
    <dbReference type="STRING" id="930090.W6ZHK9"/>
    <dbReference type="GeneID" id="19119837"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_131"/>
    <dbReference type="eggNOG" id="KOG0477">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000995_0_1_1"/>
    <dbReference type="OrthoDB" id="844at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140445">
        <property type="term" value="C:chromosome, telomeric repeat region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071162">
        <property type="term" value="C:CMG complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000792">
        <property type="term" value="C:heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006267">
        <property type="term" value="P:pre-replicative complex assembly involved in nuclear cell cycle DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17753">
        <property type="entry name" value="MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000002">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000138">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008045">
        <property type="entry name" value="MCM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF44">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12619">
        <property type="entry name" value="MCM2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01658">
        <property type="entry name" value="MCMPROTEIN2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="20">
        <location>
            <begin position="479"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00074927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00078186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC51332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="858" mass="95604" checksum="6719164B1BFB75BE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI65</accession>
    <name>W6ZI65_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_35270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_35270"/>
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    <dbReference type="OrthoDB" id="3547571at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="244" mass="25951" checksum="CDBF8A58B71123CE" modified="2014-04-16" version="1">MFLAVFSELRCVLSLSNFHFCHSVTHPSSYVQKLSLILSPFVCFESHVSQRCNDTPQNHFSPNPPTYTDGSPNKPRVANTGYDCYFDTAHGLWGFCPTPVTASSGCSLVGFCFDSVACTTGWGTETLRAVTNYVDTFTTTSQSFSFLASLITSPVSPAESPNPSASTSFSLSFHSSNIGAISGGAVAAIVVICLTVLGVLLIRWKGCKGGKAASKNDSGHSMQGLVGGKKSGEQVKSRYEAVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ57</accession>
    <name>W6ZJ57_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ57"/>
    <dbReference type="GeneID" id="19126188"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83108"/>
    <dbReference type="HOGENOM" id="CLU_167692_0_0_1"/>
    <dbReference type="OrthoDB" id="10388242at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="118" mass="13155" checksum="83FC667B891FAEA1" modified="2014-04-16" version="1">MKTTLVPCFPLRLVLHIFKGLRRFSWNKLLGHTIVVHMCNIQRSSMAATSCSESSHSIKDIAPFHVTFSLVRTTSSSSSYLLCTLYECIVECSTFGHLADVEGFMSNITDGIAKDIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJB4</accession>
    <name>W6ZJB4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963926">
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    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="19120250"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22434"/>
    <dbReference type="HOGENOM" id="CLU_1885409_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
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    <dbReference type="Gene3D" id="3.40.50.300">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="135" mass="14867" checksum="E4F8A1D25C044B13" modified="2014-04-16" version="1">MSRGIPRRLFPYRLFGVDGQVTVFRQTSSMEADGKPIVKYLTKQAELPGQLEEEERRENQCGFLACKSGIMVATTAFNAGVDVPESWIIPSQNGKRCVVRILLGDKLKSFFKNSAPPSPSTSLRSAQTVSRTVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJN7</accession>
    <name>W6ZJN7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_38252</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689639.1">
        <property type="nucleotide sequence ID" value="XM_007691449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJN7"/>
    <dbReference type="GeneID" id="19123432"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38252"/>
    <dbReference type="eggNOG" id="ENOG502S165">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066042_6_0_1"/>
    <dbReference type="OrthoDB" id="3501153at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053008">
        <property type="entry name" value="Phomopsin_biosynth_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="228" mass="26495" checksum="A4C315BBD8225E42" modified="2014-04-16" version="1">MNPNDDLEKPLMARSCDSEQSESSTLLEHRTIGLQERIQARIRWSLYLQMVILFITVLTWISLFLWNQKDRGISPFALIERGHCGWSVEEAKANDCVYDIMMSSWMPRPCYDEELSEGFLRANNFTYWTSNQGGEEVSEAEVKKGEFDILFTHGTYHHQHCIYLWKLQMKAQKSAVRVLDSISRSQAHIAHCQKLLTPDFSPHTLYQLQSKTGTPIHVKPKRQTCWEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJY3</accession>
    <name>W6ZJY3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_34814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685763.1">
        <property type="nucleotide sequence ID" value="XM_007687573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJY3"/>
    <dbReference type="GeneID" id="19122648"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34814"/>
    <dbReference type="HOGENOM" id="CLU_167702_0_0_1"/>
    <dbReference type="OrthoDB" id="10358274at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="78" mass="8478" checksum="70383AD2B2D81040" modified="2014-04-16" version="1">MAALKQTRDCQCRATRIAILPDRFGLLFAVGCAAGCLRGQCRSHRQKIASSQSVVIMNLSSSWASKPTTAWPEISIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJY4</accession>
    <name>W6ZJY4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Diphthamide biosynthesis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_32205</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2 [3Fe-4S](0)-[protein] + 2 Fe(2+)-[Dph3] + NADH = 2 [4Fe-4S](1+)-[protein] + 2 [Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71239"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:17998"/>
            <dbReference type="Rhea" id="RHEA-COMP:18001"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[3Fe-4S](1+)-[protein] + Fe(2+)-[Dph3] = [3Fe-4S](0)-[protein] + Fe(3+)-[Dph3]</text>
            <dbReference type="Rhea" id="RHEA:71235"/>
            <dbReference type="Rhea" id="RHEA-COMP:17996"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:33751"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DPH3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683010.1">
        <property type="nucleotide sequence ID" value="XM_007684820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJY4"/>
    <dbReference type="STRING" id="930090.W6ZJY4"/>
    <dbReference type="GeneID" id="19122043"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32205"/>
    <dbReference type="eggNOG" id="KOG2923">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155991_4_1_1"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.660.10:FF:000001">
        <property type="entry name" value="Diphthamide biosynthesis 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF31">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DPH-type MB" evidence="9">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="83" mass="9486" checksum="CB873A0064538DFD" modified="2014-04-16" version="1">MADEELNLYDEIEIEDCFYDETLQIYHHPCPCGDRFEISIFDMRDGEDIARCPSCSLMIRIIFDPSDLPPENDDAPQSVAIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJZ8</accession>
    <name>W6ZJZ8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_24328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685660.1">
        <property type="nucleotide sequence ID" value="XM_007687470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJZ8"/>
    <dbReference type="GeneID" id="19120573"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24328"/>
    <dbReference type="HOGENOM" id="CLU_1539756_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="174" mass="17093" checksum="4F27DAE042FEF03E" modified="2014-04-16" version="1">MCWGAAAAEEGGGGGGSGSGRGSGSSGGFNTQSNSASVETLGRRTPSTAAHGPLTAGRSPPPGTSDEWPSAVGGWAPGINCSFKRPPTGCALFLSASARKHDAGSHTVDPAHRPGGRTPAACCSSGLVGQVGLLFHRVAILSVAIIIAIIMITPTTTTTTTISIPISANVAADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK24</accession>
    <name>W6ZK24_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_6651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964015">
        <property type="protein sequence ID" value="EUC43946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689506.1">
        <property type="nucleotide sequence ID" value="XM_007691316.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZK24"/>
    <dbReference type="GeneID" id="19125033"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6651"/>
    <dbReference type="eggNOG" id="ENOG502R7J1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004333_0_0_1"/>
    <dbReference type="OrthoDB" id="4066896at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031991">
        <property type="term" value="P:regulation of actomyosin contractile ring contraction"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Bud3_C"/>
    </dbReference>
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        <property type="entry name" value="DBL_dom_sf"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR051492">
        <property type="entry name" value="Dynamin-Rho_GEF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834:SF21">
        <property type="entry name" value="GUANYL NUCLEOTIDE EXCHANGE FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN FUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PH_BUD3_C"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="245"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="826"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1113"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1405"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1501"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="852"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1113"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1509"/>
            <end position="1525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1548" mass="170906" checksum="0E1118ACF5CEB9A0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKN5</accession>
    <name>W6ZKN5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sister chromatid cohesion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_81596</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the SCC2/Nipped-B family.</text>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704:SF18">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
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    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="1427"/>
            <end position="1610"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1818"/>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU364107"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF12830"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1843" mass="204631" checksum="34AE357DBD4E118B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL93</accession>
    <name>W6ZL93_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_77060</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964006">
        <property type="protein sequence ID" value="EUC44361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689161.1">
        <property type="nucleotide sequence ID" value="XM_007690971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZL93"/>
    <dbReference type="STRING" id="930090.W6ZL93"/>
    <dbReference type="GeneID" id="19125368"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_77060"/>
    <dbReference type="eggNOG" id="ENOG502R8BE">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_138_0_1"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF11">
        <property type="entry name" value="HET-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="25"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="235" mass="27325" checksum="AAF3CE7C6F5F3D33" modified="2014-04-16" version="1" fragment="single">MRLIEFENQDKFSVTKDLHNEVPPYAILSHTWEADEEEVTLQDIVTGTGKDKAGYRKTQFCGERAASDGLRYFWVDSCCIDRSNYTELSEAINSMFRWYKHAAKCYVYLTDVSANTEKTWESDFRSSRWFTRGWTLQELLASPEVEFFSREGTKLGTKKSLEQQIHEITGIPIQALAGCPLSDFRIEERLSWAEKRQTKREEDEAYSLLGLFDLHIPLIYGEGRSNARTRLLHEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP96</accession>
    <name>W6ZP96_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cell morphogenesis protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_5346</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
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                <person name="Salamov A."/>
                <person name="Sun H."/>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="2564" mass="286929" checksum="A8BCFB074F67819E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 11">ATCC 44560</strain>
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    </reference>
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    </dbReference>
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        <location>
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        </location>
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        </location>
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        </location>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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        </submittedName>
    </protein>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685471.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_83551"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_000022_31_1_1"/>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05274">
        <property type="entry name" value="KR_FAS_SDR_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ADH_N"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="10"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="11">
        <location>
            <begin position="893"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2369"/>
            <end position="2451"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="7">
        <location>
            <begin position="893"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="7">
        <location>
            <begin position="1036"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2321"/>
            <end position="2351"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="7">
        <location>
            <position position="925"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="7">
        <location>
            <position position="1094"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC49774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="2465" mass="267989" checksum="C1BDFB3E128316FF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQT4</accession>
    <name>W6ZQT4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_32863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685464.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZQT4"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="203" mass="21993" checksum="3F3C7475E69B99C2" modified="2014-04-16" version="1">MTTTLIGLPKTLIPPLFTALTLAPLITSTASLTHAYMEYLTTSAFLNPPPLSSRLSKAILASPSPFSSAPTTSDPETHLQKEDAVNQLKEANQLAIPAWFTTFFNTGIYSVVALNTLTLSFSLANIYLLHPSFTTRGSIARRWYVIGAAATAAHYAFVPLVGRSVRALVGLCSGEKGEGRAEEWLREWRGWHGVRMGSVDLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSG9</accession>
    <name>W6ZSG9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_4301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC46646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686810.1">
        <property type="nucleotide sequence ID" value="XM_007688620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSG9"/>
    <dbReference type="STRING" id="930090.W6ZSG9"/>
    <dbReference type="GeneID" id="19124194"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4301"/>
    <dbReference type="eggNOG" id="ENOG502SAFQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="21589at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039751">
        <property type="entry name" value="HERPUD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12943:SF27">
        <property type="entry name" value="HOMOCYSTEINE-INDUCED ENDOPLASMIC RETICULUM PROTEIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12943">
        <property type="entry name" value="HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="95"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="746" mass="81250" checksum="B113AFAFED84B462" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZT49</accession>
    <name>W6ZT49_COCMI</name>
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        </recommendedName>
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        <name evidence="7" type="ORF">COCMIDRAFT_80993</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the U2 small nuclear ribonucleoprotein A family.</text>
    </comment>
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        <property type="nucleotide sequence ID" value="XM_007684519.1"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0071014">
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        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="U2 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease Inhibitor"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00024196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="244" mass="27342" checksum="A8E9F0336C1A2CC7" modified="2014-04-16" version="1">MRLTTDLINNSLSFINCLTERELDLRGHKISAIENMGAARDNDAIDLTDNDIGQLGNFPLQPRLRTLLLAQNRVSNIQPSLSSSIPNLRTLVLTKNRIAELADLDPLAGFKSLTYLSLMGNPVTSKENYRYWVIWRCPSVRFLDFTKVRDVERKKAQELFGSADEPTELANQISSNKSKGFVVPTFANGPDSSKERIYTDDERKRMRAAILNASSLAEMAQLEKDFAEGRIPAHILEGGDPMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTE7</accession>
    <name>W6ZTE7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_81111</name>
    </gene>
    <organism evidence="8 9">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC50809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684581.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19125803"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81111"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887075" evidence="5">
        <location>
            <begin position="24"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="551"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="594"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="118"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="613" mass="66243" checksum="5399722904661CA4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUL3</accession>
    <name>W6ZUL3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA ligase</fullName>
            <ecNumber evidence="1">6.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_89978</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m = (ribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRL1 family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.3" evidence="1"/>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686032.1">
        <property type="nucleotide sequence ID" value="XM_007687842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUL3"/>
    <dbReference type="STRING" id="930090.W6ZUL3"/>
    <dbReference type="GeneID" id="19127590"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89978"/>
    <dbReference type="eggNOG" id="ENOG502QQB9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010316_1_0_1"/>
    <dbReference type="OrthoDB" id="276239at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051730">
        <property type="term" value="F:GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001690">
        <property type="entry name" value="tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019039">
        <property type="entry name" value="T4-Rnl1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012387">
        <property type="entry name" value="Trl1_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015966">
        <property type="entry name" value="tRNA_lig_kin_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015965">
        <property type="entry name" value="tRNA_lig_PDEase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004:SF1">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09511">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08302">
        <property type="entry name" value="tRNA_lig_CPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08303">
        <property type="entry name" value="tRNA_lig_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019634">
        <property type="entry name" value="tRNA_lig_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="T4 RNA ligase 1-like N-terminal" evidence="6">
        <location>
            <begin position="69"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA ligase kinase" evidence="5">
        <location>
            <begin position="393"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA ligase phosphodiesterase" evidence="4">
        <location>
            <begin position="555"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="606"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="616"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR019634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR019634-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="827" mass="93976" checksum="5BEC2C1D8ABDCB91" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUP9</accession>
    <name>W6ZUP9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_79522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682208.1">
        <property type="nucleotide sequence ID" value="XM_007684018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUP9"/>
    <dbReference type="GeneID" id="19125494"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79522"/>
    <dbReference type="HOGENOM" id="CLU_2236121_0_0_1"/>
    <dbReference type="OrthoDB" id="10318910at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC51289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="105" mass="12158" checksum="992039904FDC5C15" modified="2014-04-16" version="1">MCTTYQTHYTRCERKGYGRGLKGDLPCTDEYMDECRNAQKIDETCAAPTIKCRWIDFECGKHGGPSPCEREKMIKERKGQGKEEGTWVKKKDMRSECDAMFCTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZV76</accession>
    <name>W6ZV76_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_89622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685894.1">
        <property type="nucleotide sequence ID" value="XM_007687704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZV76"/>
    <dbReference type="STRING" id="930090.W6ZV76"/>
    <dbReference type="GeneID" id="19127513"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89622"/>
    <dbReference type="eggNOG" id="KOG1379">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029404_1_0_1"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000118">
        <property type="entry name" value="Phosphatase 2C-like domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF24">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="115"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="398" mass="44466" checksum="BD88F92850A3008A" modified="2014-04-16" version="1">MLAPAFRVRNKPHLQHPLSQAWRTTIQQSAPQRTRILSVTINFKRHSRWYSEDVPKAQIGGGTTTPVPPNADPPKSKPPFYFEAGYALFAKRPSRPFPPPFLSMPSTSFSEPLSTYNKSRDRRPTVNGQMIRGVTNGDDAVLVSESFIAANDGVGAWATRERGHAALWSRLIAHFWALEVETATYNATTPPEPVTYLQNAYKLTQQATSKPSAWYGTTTTCGALLSADNEEPNHPVLYVTQLGDSQILVIRPSTREVVFRTQEQWHWFDCPRQIGTNSPDTPSENAMVDRVEIQEDDVVIAMTDGVVDNLWEHEIVENVCNSMVRWSGDKDKDTEEQTYADGMQFVAQQLVNAAREIALDPFAESPYMEKAIDEGLSIEGGKLDDISVVAAQCKRRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX41</accession>
    <name>W6ZX41_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_23783</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685015.1">
        <property type="nucleotide sequence ID" value="XM_007686825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX41"/>
    <dbReference type="STRING" id="930090.W6ZX41"/>
    <dbReference type="GeneID" id="19120495"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23783"/>
    <dbReference type="eggNOG" id="KOG4157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024893_0_0_1"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF23">
        <property type="entry name" value="PLASMA MEMBRANE SENSOR TRANSDUCER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887329" description="WSC domain-containing protein" evidence="9">
        <location>
            <begin position="22"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="10">
        <location>
            <begin position="43"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="142"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="280" mass="29625" checksum="310AEB03E5D496BC" modified="2014-04-16" version="1">MVSFGFASALAAASIIAMASAETGTPTIKNPITTPTVTKPASAMTSIGCFETGLPLENHGSYNFQSPGNCQLVCLQLDKDVMGLSDGENCWCGDEIPAKAWQVKNETCSTTCSGDDTTGCGGKNLLWVVLTGNTRNQVDYFQPSSSSSSSSLAPQTSSTAPSSTAVASATAVPVQPPPQDDKPNTVAIAVGVVVGILGLAAILFGVWFLLRRRRQQQAEEDYRRNAANVNSFVGSGKLHTSNSSMNDSRLDPSFMDRRQSNGSIADNEDYSRRILKVTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W7A251</accession>
    <name>W7A251_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_32666</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683423.1">
        <property type="nucleotide sequence ID" value="XM_007685233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A251"/>
    <dbReference type="STRING" id="930090.W7A251"/>
    <dbReference type="GeneID" id="19122155"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32666"/>
    <dbReference type="eggNOG" id="KOG1687">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055737_1_0_1"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12280:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit B 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005012">
        <property type="entry name" value="PRK06411.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56770">
        <property type="entry name" value="HydA/Nqo6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase-like 20kDa subunit" evidence="5">
        <location>
            <begin position="106"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="231" mass="25318" checksum="71CDF7E1D8548891" modified="2014-04-16" version="1">MLSTTRSAASMALRAKPATALMPLRAGSVAFLSSSSSNNATTMKSPATIPGNPGTPPPMKSARVEVPLPSQEGKKGAMQYALTTLDQVANWARQSSLWPMTFGLACCAVEMMHLSAPRYDQDRLGIIFRASPRQSDVMIVAGTLTNKMAPALRQIYDQMPDPRWVISMGSCANGGGYYHYSYSVTRGCDRVVPVDIYVPGCPPTAEALMYGVFQLQKKMRHTKITRMWYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W7A471</accession>
    <name>W7A471_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SPT2 chromatin protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_80678</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682569.1">
        <property type="nucleotide sequence ID" value="XM_007684379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A471"/>
    <dbReference type="STRING" id="930090.W7A471"/>
    <dbReference type="GeneID" id="19125708"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80678"/>
    <dbReference type="eggNOG" id="ENOG502QRJX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_774257_0_0_1"/>
    <dbReference type="OrthoDB" id="5430658at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013256">
        <property type="entry name" value="Chromatin_SPT2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00784">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="337"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="230"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="39267" checksum="22E292F4D644A62B" modified="2014-04-16" version="1" fragment="single">SGNTESNAYQLPTMSSLKDIMSIIDPSARSAATASKQGPLGSAPKPAPRPVGGANGAPQAPQLKRKASGPVENGQAKVQRKEAVGGIAQANGAVRATSSPATSRPSSSTPTTSVPYRGTAAPSSSKTANPPIRKPLQSSNVPAATTKAPAPAPKPAPAAAGPAPASNAAPKKGYLAMLQKAKEKDASKPVAPPIKHEPTKILTRKERLALKAEAGVKGKKPVAGLPSKPADPKVDPSKEKKKVEVGYQGTARPARKPVEVGYKGTARPSSAPVTSSRNGTPAVKPKPNPAKGRYDGYADWDDLDDMEDDEEEDYDSDGSSAMEGGIWDVEEEEQLALKAAKKEDAEALAEENRLKKEKEERKKRLAAMAAKAKRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4B8</accession>
    <name>W7A4B8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_21667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682521.1">
        <property type="nucleotide sequence ID" value="XM_007684331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A4B8"/>
    <dbReference type="GeneID" id="19120099"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21667"/>
    <dbReference type="HOGENOM" id="CLU_077165_1_0_1"/>
    <dbReference type="OrthoDB" id="3695462at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887918" evidence="2">
        <location>
            <begin position="19"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="135" mass="14403" checksum="2E1A7B08090C2B56" modified="2014-04-16" version="1">MGASWIYLTSALCTGAVASDTQYTMSTSDFSGITGNSYQCENGMKPSVTCADPSLNNDTCSCTCTNGIMFNQPVPSPDQSSGGNDASLDICQAEKDQYMEREREAMAKLHEAELAHTSCQEGQTVELEESKTGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4T7</accession>
    <name>W7A4T7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_80447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682453.1">
        <property type="nucleotide sequence ID" value="XM_007684263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A4T7"/>
    <dbReference type="GeneID" id="19125669"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80447"/>
    <dbReference type="eggNOG" id="ENOG502RR5F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_679692_0_0_1"/>
    <dbReference type="OrthoDB" id="3794317at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="406" mass="44100" checksum="0ABE55279F940DA9" modified="2014-04-16" version="1">MSQPSTPFDGVTEDPFLSSSDQDQFSQANFEELFGPGSSDGAIFSSNNSEVFDGTDFAYGDVSLVPIDSSISSVISTPQPSNCSSNRHSSAYPTPQANKPHPYPFGTHGLYEAGIPQSVFNSRPLPIRSQTNNVHFYSTQLAPPGSRRRSLSHGDMDRVVAASMPNPTFIRLQAPRSRTIPEELRGKDLHSHCGRGSCQSPPARGRPMKPTSMPYSLQSSPLVGGMLPTPIGTPLNAVEDVDCDTNITHQNHSIENNNPFFPSFPEGLLFRQMSRPEELARSWQIIEIGALAVTNHGSIDPRLQPHTSASNQERILKKLVDIEAHLGKSGGAEALRSCKTIREVLTGRVECEEETKDMDGVFKDGEITAANTPNEAYSDLSNGCDDNEIMAMLMSQHGVREGGDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJV1</accession>
    <name>W6YJV1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Chromatin structure-remodeling complex protein rsc1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_10284</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964291">
        <property type="protein sequence ID" value="EUC39652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693830.1">
        <property type="nucleotide sequence ID" value="XM_007695640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YJV1"/>
    <dbReference type="STRING" id="930090.W6YJV1"/>
    <dbReference type="GeneID" id="19118169"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10284"/>
    <dbReference type="eggNOG" id="KOG1827">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007728_0_0_1"/>
    <dbReference type="OrthoDB" id="1742084at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04717">
        <property type="entry name" value="BAH_polybromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05522">
        <property type="entry name" value="Bromo_Rsc1_2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.490:FF:000015">
        <property type="entry name" value="Chromatin structure-remodeling complex subunit RSC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.10:FF:000048">
        <property type="entry name" value="RSC complex subunit (RSC1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037382">
        <property type="entry name" value="Rsc/polybromo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048047">
        <property type="entry name" value="RSC1/2_bromodom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062:SF21">
        <property type="entry name" value="CHROMATIN STRUCTURE-REMODELING COMPLEX SUBUNIT RSC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062">
        <property type="entry name" value="SWI/SNF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="50"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="261"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="BAH" evidence="11">
        <location>
            <begin position="374"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="153"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="531"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="569"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="608"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="621"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC39652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="888" mass="101397" checksum="F70FE2CDD375E75D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YMU3</accession>
    <name>W6YMU3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_108370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964152">
        <property type="protein sequence ID" value="EUC40607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692885.1">
        <property type="nucleotide sequence ID" value="XM_007694695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YMU3"/>
    <dbReference type="GeneID" id="19119231"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108370"/>
    <dbReference type="eggNOG" id="ENOG502RXYW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124027_0_0_1"/>
    <dbReference type="OrthoDB" id="5394233at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="189" mass="20499" checksum="58D4CBA30CA785AD" modified="2014-04-16" version="1">MPFDFDAYDRKCSQMSPEELHLEWNHYTRLISGAAASATLGGSALVFTGGVSIIGVAIGSAGFYNARKKRQILKRHLDQEHRRNRKRDMVGSAAFNGAVGLTTLGLGTLGAERVLELGIENGVFGPAAKTGVNVATGVVVNGVNTAADDRYHTNKKKREAKRTGLVVERKHKDGHKKRSSRVVSSIDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPS7</accession>
    <name>W6YPS7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_8905</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="KI964106">
        <property type="protein sequence ID" value="EUC41372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692101.1">
        <property type="nucleotide sequence ID" value="XM_007693911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPS7"/>
    <dbReference type="STRING" id="930090.W6YPS7"/>
    <dbReference type="GeneID" id="19127400"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8905"/>
    <dbReference type="eggNOG" id="ENOG502SJGH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_0_3_1"/>
    <dbReference type="OrthoDB" id="5558646at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF18">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 15" id="KW-0136">Cellulose degradation</keyword>
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    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="12 15" id="KW-0624">Polysaccharide degradation</keyword>
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            <begin position="1"/>
            <end position="18"/>
        </location>
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            <begin position="19"/>
            <end position="233"/>
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            <end position="221"/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="233" mass="24149" checksum="6B8341AD480D7BCF" modified="2014-04-16" version="1">MRLSTPLVLAAVASSATAHTIFLSLNGGAVGDGVRVPTYDGPVSDVTSNSIVCNGPPNDVPAKTNTVITVQAGSKATLTWRHTLTSGPNDVIDASHKGPVMAYLKKVSDAKTDSGVGGGWFKIAQDAFDGSKWGVDRLIANQGNQTITIPACIAPGQYLLRGELIALHSASQLLGAQFYMECAQINVIGGSASKTPATVSFPGAYKQNDAGIVYNLYTGSKTYTAPGPDVFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPX0</accession>
    <name>W6YPX0_COCMI</name>
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        <name evidence="2" type="ORF">COCMIDRAFT_110907</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="85"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC39660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="249" mass="26846" checksum="878533014F10EE01" modified="2014-04-16" version="1">MQDCTCAFYVLRTLAHVGELTTSSQVPLETALQATSTAERPSLAVLSCERCRQQRLPLTAVTILCAHLVDWLCRLWNLMDNDASEASTDASSTTTTTTTTTTTTTTTTTTTTNNSNTRSNISNLSNTININNHSESQLSLQPWKFSLGNYDLAADEADALSNELITLRLINFSAVLGSLEAALVTSGLTPSMSSSPPERFTSNPTATDLAAIAPTCLDIVRANLRLVRISIRRLKEKSLLNNSGSSTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ54</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ABC_6TM_YOR1_D1_like"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC1_TM_dom"/>
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    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF464">
        <property type="entry name" value="ABC-TYPE TRANSPORTER CICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="499"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="894"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="932"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1011"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1033"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1123"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="188"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="606"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="899"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1210"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="566"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="830"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="585"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="835"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC41532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1464" mass="162434" checksum="84B425F858FE259F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQN8</accession>
    <name>W6YQN8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_110019</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964215">
        <property type="protein sequence ID" value="EUC39970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693516.1">
        <property type="nucleotide sequence ID" value="XM_007695326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQN8"/>
    <dbReference type="GeneID" id="19119534"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110019"/>
    <dbReference type="eggNOG" id="ENOG502SHGK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006632_3_0_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC39970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="644" mass="72141" checksum="C2DD64A6A1FFFE28" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRA6</accession>
    <name>W6YRA6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptide hydrolase</fullName>
            <ecNumber evidence="14">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_10003</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M28 family. M28A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="14"/>
    <dbReference type="EMBL" id="KI964205">
        <property type="protein sequence ID" value="EUC40043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693445.1">
        <property type="nucleotide sequence ID" value="XM_007695255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRA6"/>
    <dbReference type="GeneID" id="19117587"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10003"/>
    <dbReference type="eggNOG" id="KOG2195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024336_0_2_1"/>
    <dbReference type="OrthoDB" id="10013407at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03876">
        <property type="entry name" value="M28_SGAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02130">
        <property type="entry name" value="PA_ScAPY_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000054">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041756">
        <property type="entry name" value="M28_SGAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF57">
        <property type="entry name" value="PEPTIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7 14" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 16" id="KW-0732">Signal</keyword>
    <keyword evidence="11 14" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012113358" description="Peptide hydrolase" evidence="16">
        <location>
            <begin position="16"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="17">
        <location>
            <begin position="137"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="18">
        <location>
            <begin position="248"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC40043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="519" mass="55002" checksum="12B470324AF1B547" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRH0</accession>
    <name>W6YRH0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_109392</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964186">
        <property type="protein sequence ID" value="EUC40215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693274.1">
        <property type="nucleotide sequence ID" value="XM_007695084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRH0"/>
    <dbReference type="GeneID" id="19119419"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109392"/>
    <dbReference type="eggNOG" id="ENOG502SHZD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_0_1"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="42"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="295"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="395" mass="43596" checksum="711ABA6616CF0229" modified="2014-04-16" version="1">MSTQLQNWVSNPDETHGPLMSITVWSLCGVAGFFLALRLAIQKNQGKLWYDSFILTVSWLFLLCQAILNQLSVNLGFGKHSLDINFSHFESITYLGATGLTVSTIAITLSKISFGLTLFRLTEGWIKAYVCFAMATLLIFAIPTCILPWVLCKPLTKTFVDIIPGTCMNKHPSVIYARFQAIWSAIMDISLALIPWKILWNLQMRPAEKIGVCIAMSLGVLAGVTAILRGRYVELLTKLDLSYDATNTVIWSAAESSMAIVATSIPVLRVFFRQAVTSVISSYQNSSRERRFKSQAPNQSGTNSSVHASKLGSKNTKVEATSSATNKRRSNMLASDGTTNISEESLVNSDGKRREAYVEMDNLVVDEVTGRVTLASPESMNSLEEGLPHRPHTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRJ4</accession>
    <name>W6YRJ4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF1014-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_109316</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC124 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964183">
        <property type="protein sequence ID" value="EUC40235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693241.1">
        <property type="nucleotide sequence ID" value="XM_007695051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRJ4"/>
    <dbReference type="STRING" id="930090.W6YRJ4"/>
    <dbReference type="GeneID" id="19119408"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109316"/>
    <dbReference type="eggNOG" id="KOG3223">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069723_1_1_1"/>
    <dbReference type="OrthoDB" id="76412at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010422">
        <property type="entry name" value="Ccdc124/Oxs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054414">
        <property type="entry name" value="Ccdc124/Oxs1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054413">
        <property type="entry name" value="LSO1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06244">
        <property type="entry name" value="Ccdc124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22048">
        <property type="entry name" value="LSO1_2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LSO1/LSO2" evidence="5">
        <location>
            <begin position="15"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Coiled-coil" evidence="4">
        <location>
            <begin position="115"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24288" checksum="DCE6AED1333C136B" modified="2014-04-16" version="1">MAKKGGAGAGASENSKKAQGQARKAEAAASKQAAKNQQAEKEEAEEWKKGAKSNAKAEAAAEKAAEAARKKAEKEALLREEEASMPSKPKGKAPKAEKKPRGIDAALGSLDGKPSALNASGIDNALDALDITGNTQEKIDRHPERRFKAALAAYEEDRLAEMKDDKTLRRQQKIEIIRKEFEKHPDNPYRQVTGAYNMTREERAAIQEEERAKKEKRLVGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT57</accession>
    <name>W6YT57_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964054">
        <property type="protein sequence ID" value="EUC42647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690839.1">
        <property type="nucleotide sequence ID" value="XM_007692649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT57"/>
    <dbReference type="GeneID" id="19121376"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28771"/>
    <dbReference type="HOGENOM" id="CLU_1740176_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="150" mass="16446" checksum="64E80B44FDAA2638" modified="2014-04-16" version="1">MVRAMVPALIEANGNTKSDTDWEMLRIGPVFSVGTWIQGCGWRRVIPDDEDGDDKRGSHNQGTLQRRCKEAVFGSGSGSGSGDGGVGGVWSGDHSLLSSRPGRPRKERWRRRLEPGWTKKALLPRASGERWVFTYMYGRLGLSGLVGSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTZ6</accession>
    <name>W6YTZ6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_28551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964045">
        <property type="protein sequence ID" value="EUC42927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690559.1">
        <property type="nucleotide sequence ID" value="XM_007692369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTZ6"/>
    <dbReference type="GeneID" id="19121326"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28551"/>
    <dbReference type="HOGENOM" id="CLU_1440814_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886758" evidence="2">
        <location>
            <begin position="23"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="188" mass="20154" checksum="4406693FEA3B7FF2" modified="2014-04-16" version="1">MPARRLLTRISTLATRFAVSWGLPGSGAVCDVETAMSKGVVSARGRGGEEEKYQALAGAGSAVMLFIKRLGTASVYRCRRWTSAAPLSILGLDDEFSPGDSAVSSPVWVHCHTSRPNNATDKGRESLESSTSELQSPLATPIRWHTDHTLDSPNAAGGSSRHAYACHAQRMLRSHGPKRRSAAHPSYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV68</accession>
    <name>W6YV68_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_8839</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fructosamine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="KI964102">
        <property type="protein sequence ID" value="EUC41443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692023.1">
        <property type="nucleotide sequence ID" value="XM_007693833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV68"/>
    <dbReference type="STRING" id="930090.W6YV68"/>
    <dbReference type="GeneID" id="19127251"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8839"/>
    <dbReference type="eggNOG" id="KOG3021">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036517_0_3_1"/>
    <dbReference type="OrthoDB" id="5772781at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102193">
        <property type="term" value="F:protein-ribulosamine 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1200.10:FF:000018">
        <property type="entry name" value="Fructosamine-3-kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="331" mass="36461" checksum="B10403B98C300AD0" modified="2014-04-16" version="1">MMKVDPAFIKLLGLDSDKTTISSVGGSSFASTSQIVSRLDDGSEKAYFMKTGSGKAAEVMFAGEDASLKAIYKAVPTLCPQSFGYGQFVAQPSKWFLVTEFLYLNSFSASRSSKTVSLAAKLAQLHTTPAPIPDGYDMPMFGFPVTTCCGETPQDNSYKESWADFYAENRLMFIIRHAEQRGRKDNDLRKLIEHTATKVVPRLIGDGHLNNGQRVTPVVVHGDLWSGNASVGMIGSEKGKVEDVVYDSSACYAHSEFELGIMKMFGGFGGSFMKEYHQLCPKTEPVNEYEDRVQLYELYHHLNHYAMFGASYRSGAVGIMKSLIEKYGGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVP6</accession>
    <name>W6YVP6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_111157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964321">
        <property type="protein sequence ID" value="EUC39584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693896.1">
        <property type="nucleotide sequence ID" value="XM_007695706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVP6"/>
    <dbReference type="GeneID" id="19119723"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111157"/>
    <dbReference type="eggNOG" id="ENOG502SPK2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_526868_0_0_1"/>
    <dbReference type="OrthoDB" id="2522477at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="553" mass="62598" checksum="D6AFBECE99BBDD3F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVR0</accession>
    <name>W6YVR0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_105689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964094">
        <property type="protein sequence ID" value="EUC41618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691869.1">
        <property type="nucleotide sequence ID" value="XM_007693679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVR0"/>
    <dbReference type="GeneID" id="19118730"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105689"/>
    <dbReference type="HOGENOM" id="CLU_3037810_0_0_1"/>
    <dbReference type="OrthoDB" id="10274488at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="55" mass="6331" checksum="4B2BBB45F8D3369F" modified="2014-04-16" version="1" fragment="single">ILGLVWTCICFYSSIHPLYIVLPARVEYCTLTSSLHTNPARVHDRDEHQRLFTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW43</accession>
    <name>W6YW43_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_29501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964087">
        <property type="protein sequence ID" value="EUC41763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691710.1">
        <property type="nucleotide sequence ID" value="XM_007693520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW43"/>
    <dbReference type="GeneID" id="19121516"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29501"/>
    <dbReference type="eggNOG" id="ENOG502SHHA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_3_3_1"/>
    <dbReference type="OrthoDB" id="9984533at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="304" mass="33692" checksum="4EA79AC243DB1666" modified="2014-04-16" version="1">MTITNVALIGGTGTLGAPVLRALQASEFSLYVLNRQSSKSVYPKTNVITVPDDLDVDAVAKALRSKNIDALIITIAGSHVDSQKKLIDAAFKAGVKRVMPAEFGSCDSADDKTNEILPLMKGKKVVRDYLISLQDQQREPGMGNLTWTSLITGHFFDWGMTCGLLKFDVKARKAYLLDGGNIKFSASNVDFIGKAVVRVLEKEEQTKNKLLYVHSLRVTQLEVLEALEKATGEKFERVEQKSEEELEVCRPKMLEGDMEAREEVVAVWGVVASDWKEREGFANELLGLEEQDLDEVVKRVVSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWI0</accession>
    <name>W6YWI0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_110276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964230">
        <property type="protein sequence ID" value="EUC39884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693600.1">
        <property type="nucleotide sequence ID" value="XM_007695410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWI0"/>
    <dbReference type="STRING" id="930090.W6YWI0"/>
    <dbReference type="GeneID" id="19119574"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110276"/>
    <dbReference type="eggNOG" id="KOG3968">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_2_1_1"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01298">
        <property type="entry name" value="ATZ_TRZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050287">
        <property type="entry name" value="MTA/SAH_deaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794:SF11">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794">
        <property type="entry name" value="AMINOHYDROLASE SSNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="69"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="485" mass="51954" checksum="011F63F8128BFE01" modified="2014-04-16" version="1">MSSISAAPRRLLVHATIITVNKSREVILDGALLIENGRISLIGKTAELLNQVQSENNPDLEIIDCTNKIVIPGLINTHAHLAQSLLRGLAEDLPLHNWLCDAVWPLEANYAEDDGYAASMLTIAEMLKTGTTCFLEAMLTHRSGLENVVRAVQETGIRACLGKLIKVAETNANLNMKDARDRDVDSMSVAAALSAHKKHHSTCNDRLHVWFAAGTPRGSPMAAHASIGETARSQNIGVTMHCAEAPKDLPIYHEYYQCSPMQFCRDASLTGPKSVFAHCVHLDPAAGDYDVLRESNSTVSHNPTSNLKLGSGVASIPDMVASGVNVALGTDGAPCNNTYDMFREMHLAAILHGGVRQQAGVLSAYDVLEFATINGAKALGLDKEIGSLEVGKKADVVVVEPRGVSNIPWVASEQSTGGMDPVTVLVHSSGADVDTVIVDGQVLVSKGRLLHIDECIIMDQARDSIAGIRQRSGVGARNHMSLKYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWN9</accession>
    <name>W6YWN9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_104786</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964079">
        <property type="protein sequence ID" value="EUC41948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691532.1">
        <property type="nucleotide sequence ID" value="XM_007693342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWN9"/>
    <dbReference type="GeneID" id="19118571"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104786"/>
    <dbReference type="eggNOG" id="ENOG502T1TY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079673_0_0_1"/>
    <dbReference type="OrthoDB" id="4156595at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="257" mass="28340" checksum="A529EE0F8E0F8C35" modified="2014-04-16" version="1">MAAAAAAATTHQHRHQLQTHPPSPQATRRRHKKKPDPFEQLATTPIPSPPSSPASALHDSNEPLLARIILTPIFFTSFLLSLFLVNYRNRARRTHAHASSSSSSSSSTSYPYSSSASSLLAYLVPSRWLHPEPYQDPDDSTWGRRDTALHVEPHDAISPKQQDAQAGFVRMGTKKNQKNNNNNNKKTSWHLHKKICKVAKMEIGDALEMRGRMIAAMAAFALVAGVAGWMGLRWCFVSLSHAWSAAQGQHHGIATTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXF8</accession>
    <name>W6YXF8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_109402</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="KI964186">
        <property type="protein sequence ID" value="EUC40214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693273.1">
        <property type="nucleotide sequence ID" value="XM_007695083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXF8"/>
    <dbReference type="STRING" id="930090.W6YXF8"/>
    <dbReference type="GeneID" id="19119423"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109402"/>
    <dbReference type="eggNOG" id="KOG1383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019582_2_2_1"/>
    <dbReference type="OrthoDB" id="5152799at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.160:FF:000004">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.50:FF:000001">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF6">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC40214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="524" mass="59451" checksum="471FE90A16981084" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXX4</accession>
    <name>W6YXX4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964062">
        <property type="protein sequence ID" value="EUC42418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691068.1">
        <property type="nucleotide sequence ID" value="XM_007692878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXX4"/>
    <dbReference type="GeneID" id="19123701"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39527"/>
    <dbReference type="HOGENOM" id="CLU_129947_0_0_1"/>
    <dbReference type="OrthoDB" id="3793724at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889503" evidence="1">
        <location>
            <begin position="17"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="177" mass="19105" checksum="8F42334B709F79CA" modified="2014-04-16" version="1">MRFFVTLSLLTSGAFAVWNAKVCNNAGGCVSGVTRLPDPFRCPDGTGVNLQQSASADLGTSAGEYDIISKSQFPDHCLYGAKPGANDLLVVKTLDLDRKMYSFISQTCTDKNPPVNCYNKRPNPGSSTVCLIVDSKGRECVANPSAGQCERGLTKLHRPDPCLGWKLGMPDQPEKQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYE9</accession>
    <name>W6YYE9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_103083</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964055">
        <property type="protein sequence ID" value="EUC42598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690879.1">
        <property type="nucleotide sequence ID" value="XM_007692689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYE9"/>
    <dbReference type="STRING" id="930090.W6YYE9"/>
    <dbReference type="GeneID" id="19118217"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103083"/>
    <dbReference type="eggNOG" id="KOG2930">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115512_2_1_1"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16485">
        <property type="entry name" value="mRING-H2-C3H2C2D_RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000010">
        <property type="entry name" value="E3 ubiquitin-protein ligase RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="56"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC42598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="111" mass="12630" checksum="EE5444E714060C3B" modified="2014-04-16" version="1">MADAPPAKTKTSKAGASGEGDKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGICNHAFHFHCISRWLKTRQVCPLDNRDWEFQKYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYF8</accession>
    <name>W6YYF8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal eL28/Mak16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_39351</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964055">
        <property type="protein sequence ID" value="EUC42608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690871.1">
        <property type="nucleotide sequence ID" value="XM_007692681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYF8"/>
    <dbReference type="STRING" id="930090.W6YYF8"/>
    <dbReference type="GeneID" id="19123667"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39351"/>
    <dbReference type="eggNOG" id="KOG3412">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106801_0_0_1"/>
    <dbReference type="OrthoDB" id="338850at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.110:FF:000002">
        <property type="entry name" value="60S ribosomal protein L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002672">
        <property type="entry name" value="Ribosomal_eL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10544">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="5">
        <location>
            <begin position="9"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="151" mass="16332" checksum="581B6BFAD85883CF" modified="2014-04-16" version="1">MATTISHDLAWEITKGRSSTLVKRANGVQFSRDPLNLRNLYSRKNEGSIANKAIGVIPGKEGGVTLLIKKADKHHQPASAIQTTTFGPSKSTRKTYSAIVNATTKRNYRPDLRKDAVARASAIRKSQKPVKADKPSKPRGVKAKAAAAEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYS5</accession>
    <name>W6YYS5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Meiotic nuclear division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_37610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the MND1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688932.1">
        <property type="nucleotide sequence ID" value="XM_007690742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYS5"/>
    <dbReference type="STRING" id="930090.W6YYS5"/>
    <dbReference type="GeneID" id="19123285"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37610"/>
    <dbReference type="eggNOG" id="KOG3433">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080628_0_0_1"/>
    <dbReference type="OrthoDB" id="9978204at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005647">
        <property type="entry name" value="Mnd1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040453">
        <property type="entry name" value="Mnd1_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03962">
        <property type="entry name" value="Mnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026991">
        <property type="entry name" value="Mnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mnd1 HTH" evidence="7">
        <location>
            <begin position="15"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="85"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR026991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="222" mass="24867" checksum="4E10371535C29981" modified="2014-04-16" version="1">MAPKIQPNPQKAASILAWFHKTAQAHSIKDLEKTLPQVSSINGMQVKDYLQALSDDSKIRVEKIGSGNWYWSFPADEKKAKNAILKKAQEEYGKASVAVSELQARVEGAEAARAEDEDMLMEPGGNRQTLIAKHADLTKELEQLRTDLVAYSEQDPDELEKKESEAHKARLDAEKYTDHILAMQGWFKTNVGGGEGGEDFLNLLKMLYGDEYDSEEQGLREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ92</accession>
    <name>W6YZ92_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Calcium-channel protein CCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_7576</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Voltage-gated, high-affinity calcium channel that functions together with MID1 to mediate calcium entry into cells. Required during conditions of environmental stress.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964045">
        <property type="protein sequence ID" value="EUC42908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690553.1">
        <property type="nucleotide sequence ID" value="XM_007692363.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6YZ92"/>
    <dbReference type="GeneID" id="19125323"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7576"/>
    <dbReference type="eggNOG" id="KOG2301">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000443_0_0_1"/>
    <dbReference type="OrthoDB" id="416585at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000093">
        <property type="entry name" value="Calcium channel subunit Cch1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000118">
        <property type="entry name" value="Calcium channel subunit Cch1"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="456" mass="50799" checksum="131CDFF6A81197F2" modified="2014-04-16" version="1">MAIYSSVTGAVSSILSPVTSQGWGPLVSLCKNGTLSQFQNLKHGKLVVFEGGSSKSSVAFGSDKEGLPIAFLDVRDEKFWVRIALFADMGFAESYMLGEVSTPDLTKFFELFILNRNYLSNGSTFTSAISSGLAGLLRGSNNLRNARLNISAHYDISNEMFAAFLSQDMTYSCPIWLPKSNPLSANETLYEAQMRKLDRFIDNTHIKGTDHVLEIGTGWGSFAMRAVERTGCRVTSLTLSIEQKELAEERIRAAGMSDKISVLLCDYRSLQVPETGPFDKVVSIEMLEAVGKEYLVTYFKCIDKLLKKEGGIACFQCITMPDARYEAYAKSDDFIRRYIFPGGHLPAVSELVASINTGSEGSLIVDSIENIGPHYAKALRLWREKFLDSWESTIKPQLIKEKSSEGMDDEGAEIFKRKWDYYFRYSEAGFSTRTLGDVIITVSREGAMQMMEEVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZG0</accession>
    <name>W6YZG0_COCMI</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13898"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="5.4.99.5" evidence="4 13"/>
    <dbReference type="EMBL" id="KI964043">
        <property type="protein sequence ID" value="EUC42978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007692320.1"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="reaction ID" value="UER00203"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:L-tyrosine binding"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Chorismate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.590.10">
        <property type="entry name" value="Chorismate mutase, AroQ class superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
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        <property type="entry name" value="Chorismate_mutase_AroQ_euk"/>
    </dbReference>
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        <property type="entry name" value="CM_AroQ_sf_eucaryotic"/>
    </dbReference>
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        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01802">
        <property type="entry name" value="CM_pl-yst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21145">
        <property type="entry name" value="CHORISMATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21145:SF12">
        <property type="entry name" value="CHORISMATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017318">
        <property type="entry name" value="Chor_mut_AroQ_eu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="Chorismate mutase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51169">
        <property type="entry name" value="CHORISMATE_MUT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0827">Tyrosine biosynthesis</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="14">
        <location>
            <begin position="146"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR017318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC42978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="266" mass="30486" checksum="9E7B6C4C06623B3D" modified="2014-04-16" version="1">MDAAIDLSDASKALDLANIRFQLIRLEDTITFHLIERVQFPLNQTIYRPGGVDIGEPNTSLFDWMLREQERLQSLVRRYQSPDEYPFFPEVLQEPILKPINYPQILHPNDVNVNAKLKDCYIKHILPAACLQTERGDRGESQENYGSSATCDVLTIQALSRRIHFGKFVAEAKFQQETERFVKLIKDEDRKGIDEAITNAAVEKKVLERLRLKAKTYGTDPDLGANGSSKVDADAVVAMYKDWVIPLTKEVEVEYLMQRLKGTQWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZH9</accession>
    <name>W6YZH9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_101938</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Tom70 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964042">
        <property type="protein sequence ID" value="EUC43015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690472.1">
        <property type="nucleotide sequence ID" value="XM_007692282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZH9"/>
    <dbReference type="STRING" id="930090.W6YZH9"/>
    <dbReference type="GeneID" id="19117977"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101938"/>
    <dbReference type="eggNOG" id="KOG0547">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017516_0_1_1"/>
    <dbReference type="OrthoDB" id="2942533at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005687">
        <property type="entry name" value="Tom70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00990">
        <property type="entry name" value="3a0801s09"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 10" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="339"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="407"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="475"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="550"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="67"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC43015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="626" mass="69373" checksum="A5DEDD32B33DFB20" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZM3</accession>
    <name>W6YZM3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_101947</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964042">
        <property type="protein sequence ID" value="EUC43033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690482.1">
        <property type="nucleotide sequence ID" value="XM_007692292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZM3"/>
    <dbReference type="STRING" id="930090.W6YZM3"/>
    <dbReference type="GeneID" id="19117980"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101947"/>
    <dbReference type="eggNOG" id="ENOG502RY03">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_5_2_1"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886442" description="AB hydrolase-1 domain-containing protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="8">
        <location>
            <begin position="92"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="9">
        <location>
            <begin position="444"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC43033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="55759" checksum="118439038277A1DE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZV7</accession>
    <name>W6YZV7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Orotate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_101745</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690376.1">
        <property type="nucleotide sequence ID" value="XM_007692186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZV7"/>
    <dbReference type="STRING" id="930090.W6YZV7"/>
    <dbReference type="GeneID" id="19117924"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101745"/>
    <dbReference type="eggNOG" id="KOG1377">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074878_0_0_1"/>
    <dbReference type="OrthoDB" id="5553476at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046132">
        <property type="term" value="P:pyrimidine ribonucleoside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000008">
        <property type="entry name" value="Orotate phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683:SF1">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="65"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC43123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="233" mass="25401" checksum="109FAF1286FC3191" modified="2014-04-16" version="1">MALPEFKQNFLKDCVSAGALKFGTFTLKSKRISPYFFNAGLFHRADLLRSISSAYAHTLKAHGEADASFQWDILFGPAYKGIPLAAASVDKLADLDLAKYGQKSYSFNRKEAKDHGEGGNIVGASLKGKKIVIVDDVITAGTAIREAIDIIKREGGELVGIIVAFDRQEKTPTATDDDGKPGPSAIGEVRKQYGIPVLAILTLDDVVEYLRSLGGEEDLKRLDEYRAKYRASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z037</accession>
    <name>W6Z037_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC44997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688484.1">
        <property type="nucleotide sequence ID" value="XM_007690294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z037"/>
    <dbReference type="GeneID" id="19123204"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37230"/>
    <dbReference type="HOGENOM" id="CLU_069167_0_0_1"/>
    <dbReference type="OrthoDB" id="3694376at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="247" mass="27699" checksum="3E267AC90E3DCF1F" modified="2014-04-16" version="1">MPFRTPQPISKPPKCPPTPRPQPTHSQIPSPPHYNLTPAPPFFASLAARLAYTSEPRFLPNGELTRPDPMPGYIPVHQDDRLPVHPRPASVLSWKSGRRSERRREAKSDSMTTTTTTTTTTAEGRVEKKKKKQKEEAKVGGNLRQIDLVMRPKSEAQKRRHAGWHPCEHTAVAERQSEASTGNTSPSPCESGRLGRKRETYVRCTCCGREYQAKSPAELKTNTKLGICRDCGRRMGVEHGETEEMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z219</accession>
    <name>W6Z219_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 35 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_8641</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964091">
        <property type="protein sequence ID" value="EUC41674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691795.1">
        <property type="nucleotide sequence ID" value="XM_007693605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z219"/>
    <dbReference type="GeneID" id="19126850"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8641"/>
    <dbReference type="eggNOG" id="ENOG502QUR4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027430_0_0_1"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000135">
        <property type="entry name" value="Beta-galactosidase, putative, bgl35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.20">
        <property type="entry name" value="putative beta-Galactosidase from caulobacter crescentus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040719">
        <property type="entry name" value="DUF5597"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18120">
        <property type="entry name" value="DUF5597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 42 N-terminal" evidence="3">
        <location>
            <begin position="46"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5597" evidence="4">
        <location>
            <begin position="394"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="559" mass="62298" checksum="63D6A1AA2E20CAD5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2G1</accession>
    <name>W6Z2G1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_105172</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964085">
        <property type="protein sequence ID" value="EUC41819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691677.1">
        <property type="nucleotide sequence ID" value="XM_007693487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2G1"/>
    <dbReference type="STRING" id="930090.W6Z2G1"/>
    <dbReference type="GeneID" id="19118640"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105172"/>
    <dbReference type="eggNOG" id="KOG3216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_41_3_1"/>
    <dbReference type="OrthoDB" id="7305308at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000064">
        <property type="entry name" value="GNAT family acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051016">
        <property type="entry name" value="Diverse_Substrate_AcTransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545">
        <property type="entry name" value="DIAMINE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545:SF29">
        <property type="entry name" value="GH14572P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="6"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="173" mass="19261" checksum="0E723B33C3509CDE" modified="2014-04-16" version="1">MSSDNASLRHARREDVPTILGLIQELADYENASDKVEATEEILARTLAHHDPTTSTFSQGFARTLFIADPDGAVAGMAVYFFNFSTWTGVPGIYLEDLFVKEAYRKKGYGKRLLKELAAIVLEAGGKRLEWSCLDWNEPSLNFYQSEVIGAKRKNEWVGLRVEGDALAKLANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2V7</accession>
    <name>W6Z2V7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar complex-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_29308</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964077">
        <property type="protein sequence ID" value="EUC41994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691476.1">
        <property type="nucleotide sequence ID" value="XM_007693286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2V7"/>
    <dbReference type="STRING" id="930090.W6Z2V7"/>
    <dbReference type="GeneID" id="19121482"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29308"/>
    <dbReference type="eggNOG" id="KOG2153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012441_3_0_1"/>
    <dbReference type="OrthoDB" id="10263597at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028977">
        <property type="entry name" value="Nucleolar_complex_p3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nucleolar complex-associated protein 3 N-terminal" evidence="9">
        <location>
            <begin position="124"/>
            <end position="215"/>
        </location>
    </feature>
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        <location>
            <begin position="484"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
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        <location>
            <begin position="365"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="13"/>
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        </location>
    </feature>
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            <begin position="37"/>
            <end position="49"/>
        </location>
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            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
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        <source>
            <dbReference type="PIRNR" id="PIRNR028977"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07540"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41994.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="685" mass="76601" checksum="5E45BA8256016C85" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z353</accession>
    <name>W6Z353_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_98344</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nucleoside phosphorylase domain"/>
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    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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            <dbReference type="EMBL" id="EUC44370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="343" mass="37551" checksum="A7DEEDA8F1030731" modified="2014-04-16" version="1">MAAAQPTGALPKEQYTVGWICALPAELTAARFFLDDLHAERLEQQDTNDENTYVLGSIKGHNVVFATLPYGVYGTSSAATVARDMLRTFKNIRIGLMVGIGGGAPSRTNHIQLGDVVVSVPQNGNAGVFQYQHGKNTQGRSFKNTGHVNKPTALLLGAVASLKSKFTINGNGIAEHVHALVTKYPRLQSEFGRPDPTSDRLYSSDFIHPDDENGLHRSCDIVCGFDPQKIVDRTSWPKRYDESVVFHGVIASADTLMKNAMERDRLSQDAGVLCFEMEASGLMNSFPCLVVRGVCDYSDTHKNDQWQGYAAMCAAAYTRELLAMVAPHKVDAEPKLEIWLDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z388</accession>
    <name>W6Z388_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_98236</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
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        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC44425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:iron ion binding"/>
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    </dbReference>
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        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF6">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AN1598-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="48777" checksum="759F2C23E26422F9" modified="2014-04-16" version="1" fragment="single">YPDRPYKFLHHPGEIVILPFKYMDAIKNAPEGKLSFQQGSFDMLMGEHTGITGNDLEMATLIRRDVGRLLDRVYTIVDDEAMDALKNEIGPCEDWTEVTLLPKTVRMIVKVSQRVFVGEPLCRDERWLETILNCTAASFGSVTKLWTYNWLTRPFVAWRDPGLRSIRQYKEEARELIRPVLDQRLKDLEDPDFKAPPDLIQLVIDGFKNGKGRNLETQVATQIGTGRAALFTTGVTVFHLIYDLAAHPEYIQPLREEVIKLCDVPMNRVNVAKLVKLDSFIRECQRWSKFLLIGTMRKVIQPLTLPDGTVLPVGTLLAVDTQNAVFNNSTLEDSHKFDGFRFEKLRAQEGNAMKFQAVTTGADHLVFGYGSQACPGRFFAIHEAKVALARVLLNYDFKLKEKPVDSPMARVVGVLTTADPSVKFLFKSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3I2</accession>
    <name>W6Z3I2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase small domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_6130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="38492" checksum="0D05F7FCE5F6DAE0" modified="2014-04-16" version="1">MRYLRFLKPPRILRDKTTNTASVACLVTLVSDLGDSFLPHPVHLAAELLLCTHDAEHVLVWTSVRWASGMRSLPIAVPLPKPHALPSSLLRLRVGIGPGNSPDEYPALAGQDARGLVSAWSAHFTLDDDAPKLVQRRFSLAPHSDMAIWEETGESIARHLWDAGITLACHIPDLADTKSTLAKALLPSTKASPLTVLELGTGCGIVGIALAQTISNANVLLTDLPEAREIVQRNIDQASRAPGAKLSFLELDWNAQLPSELQSNSTSVNLVVAADCTYNPDSSPALVSTLSRLAISNPAIVVAIAMKMRHSSEQVFFHLMAHAGFIETAKLDFLLPGDIDAGEEIVYLHVYSTSMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z467</accession>
    <name>W6Z467_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_6038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688773.1">
        <property type="nucleotide sequence ID" value="XM_007690583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z467"/>
    <dbReference type="STRING" id="930090.W6Z467"/>
    <dbReference type="GeneID" id="19124805"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6038"/>
    <dbReference type="HOGENOM" id="CLU_1160932_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="239" mass="26326" checksum="DCCE5E07BA271F3E" modified="2014-04-16" version="1">MELSVTIENTIANGLSPNTSTDIKSDAISISIFYRELSVTIENTIANGLSPNTSTNIKPKAIKVQIPHAQQPSISPLLAVAAQSKLTVRLGDLCGTEVQNPIGHHPIALWTDAADTYVPPSHRESLVRDPYESPNRKLALEFNLRLSILDSQFNEKLDQDAAGKFLATRTFCSSTDRCISMICLEHQRHDQSNDLETWGKSGDIPRELDKLLASKLSKYSSLGELGKCLASELSKYIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4U5</accession>
    <name>W6Z4U5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyl-accepting transducer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_26764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC45000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688476.1">
        <property type="nucleotide sequence ID" value="XM_007690286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4U5"/>
    <dbReference type="GeneID" id="19120993"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26764"/>
    <dbReference type="eggNOG" id="ENOG502RYNN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_483094_0_0_1"/>
    <dbReference type="OrthoDB" id="3695732at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886631" description="Methyl-accepting transducer domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="49678" checksum="CD6B969EB898C91A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4Y7</accession>
    <name>W6Z4Y7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_5946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688669.1">
        <property type="nucleotide sequence ID" value="XM_007690479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4Y7"/>
    <dbReference type="GeneID" id="19124789"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5946"/>
    <dbReference type="eggNOG" id="ENOG502S9H1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120625_1_0_1"/>
    <dbReference type="OrthoDB" id="2559326at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031833">
        <property type="entry name" value="DUF4748"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41800">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41800:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15932">
        <property type="entry name" value="DUF4748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="148" mass="15895" checksum="55511A55FC82239A" modified="2014-04-16" version="1">MNTVKSVYYGWATLIVAGGGAYFFAKRSINADRAHKAELDRQKRARIYEMEHGIQSPPTTPLNPTARPGSTQAAPQSVTSELGRLRSEGGSNGGNGGMGQVEGNPSVQASQDPAPTRHAPADEGQRVGEKSKYEASDVYRSRKGDRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z580</accession>
    <name>W6Z580_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_91616</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686590.1">
        <property type="nucleotide sequence ID" value="XM_007688400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z580"/>
    <dbReference type="GeneID" id="19127915"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91616"/>
    <dbReference type="eggNOG" id="ENOG502SH77">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_12_0_1"/>
    <dbReference type="OrthoDB" id="5342292at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="46"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="263" mass="29130" checksum="E5C99BB6AC49266D" modified="2014-04-16" version="1">MDMNKPLFPAPPGYVVNLSNPQRTGEAANLWVGAVGMIIAALFMAVRIYTKTRFAKGFSADDVALIVAWFFSVTIQVIILVQYRGGTLGVHIWELSGNRVNFSLNLVNVASILYCPFLASAKLSLLLLYLRLSPLRWFRICVYGAMFIVIGYSIALLFPLLFACTPFKRNWDVTITEGSCINRTPLYMATAVLNMVTDILLLVLPIPMVVKLQVPRAQKAGLLCIFGVGSLTCITSGVRLALLFPMLNTIDQTWAIMMPGIWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z589</accession>
    <name>W6Z589_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_28692</name>
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            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC42724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z589"/>
    <dbReference type="GeneID" id="19121355"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28692"/>
    <dbReference type="HOGENOM" id="CLU_1786518_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="145" mass="15343" checksum="B88BE935B22251A7" modified="2014-04-16" version="1">MVADAALASGMQDEISFPRGGVRTRDGLKDDGQQHDQGIDDCATRLYVLDRVGLASVEDADAWRATLLEAEAASGCALAGTKREGRGGERYASSRAWMLRAAVLGIGLKGLGEWSYNDCPEKKEGGGRQPTTSLLQGDSEIAEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5V6</accession>
    <name>W6Z5V6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_102197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964044">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5V6"/>
    <dbReference type="GeneID" id="19118029"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102197"/>
    <dbReference type="HOGENOM" id="CLU_1310002_0_0_1"/>
    <dbReference type="OrthoDB" id="3678145at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="210" mass="23579" checksum="D11DBE89BE49399B" modified="2014-04-16" version="1">MLIPYEHYTKHLPDNETEITQPPDADDDYYSPLESIIETLDVLKNDFATQKYCDLKSLSATLTGGLTCNEEGIRELINEKNATQHYYDFCAYRHAKSKDTRNPETTDDASSTLSLSQDYKKGDDKRYTAAYLAESTRCFLTRDGRLGLGPRITAGGDQIWLPMGADTPFVLRPLHGGKFKILGQAYLHGVMQGEVVADLTEDNFEVVKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z650</accession>
    <name>W6Z650_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WKF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_5366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963984">
        <property type="protein sequence ID" value="EUC45460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688021.1">
        <property type="nucleotide sequence ID" value="XM_007689831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z650"/>
    <dbReference type="STRING" id="930090.W6Z650"/>
    <dbReference type="GeneID" id="19124590"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5366"/>
    <dbReference type="eggNOG" id="ENOG502S9T9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_502456_0_0_1"/>
    <dbReference type="OrthoDB" id="10261563at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019327">
        <property type="entry name" value="WKF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22306">
        <property type="entry name" value="CHROMOSOME 7 OPEN READING FRAME 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22306:SF2">
        <property type="entry name" value="CHROMOSOME 7 OPEN READING FRAME 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10180">
        <property type="entry name" value="WKF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WKF" evidence="2">
        <location>
            <begin position="311"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="510"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="542" mass="59231" checksum="B4F249A204548169" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8M9</accession>
    <name>W6Z8M9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidine acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_88510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685450.1">
        <property type="nucleotide sequence ID" value="XM_007687260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8M9"/>
    <dbReference type="GeneID" id="19127285"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88510"/>
    <dbReference type="eggNOG" id="ENOG502QSSD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030126_0_0_1"/>
    <dbReference type="OrthoDB" id="10262962at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF195">
        <property type="entry name" value="ACID PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887272" description="Histidine acid phosphatase" evidence="2">
        <location>
            <begin position="21"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="480" mass="53356" checksum="995509DA249F5F7A" modified="2014-04-16" version="1">MASHNYIALMLASIATSVSATEVDLGWYPPKKSWINDLDQILNGTGTNGFVFNSSQLPLGVEYGTYNWCNMPHVRKEEYVKADADFELAYVEVIHRHHKRTPYASNTFPRESYRWECKDQGLFYYGEPLGSTSNKTSASTYWSVYTDPVNPFAQAGFNGSCQFPQITLEGLEDSWQHGKDLYGVYHDLLGFLPSQPDTKVTYRVSNNVITSQVAGMLIQGMYNPKENVPLHVQPSDIDSLAPSYSCPAASKLYSTYGVGSSAANWTAHLTATAPLFKALDTVSGVSPTSAEWHNWFDHYYDNLSARQCHAKPLPCNISDPSLCIDQRQADSVYRLGQYEYSFIYRDAPQSLQAAAGSYGVFLAELASHIRAAMAGQSDIIYRHNVAHDGSLSRLLSFLQVEQMVWVGMGSEVVFEVYKRVGGEGKWFVRILWGGQVLRSSNPSLGWKEGCVDMLDVEVFLAYVDGLVGRGAEKVVAFCKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z932</accession>
    <name>W6Z932_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_92722</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687003.1">
        <property type="nucleotide sequence ID" value="XM_007688813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z932"/>
    <dbReference type="STRING" id="930090.W6Z932"/>
    <dbReference type="GeneID" id="19128129"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92722"/>
    <dbReference type="eggNOG" id="ENOG502SHS9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_8_6_1"/>
    <dbReference type="OrthoDB" id="3358371at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05251">
        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF26">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="3"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="341" mass="37672" checksum="78D9C87A9ABBA2AD" modified="2014-04-16" version="1">MAKKLITILGITGTQGGSVARRFLTHTNWRIRGLTRNPGSPKAKEWANKGVEIVKGDHDDLESLKAAFQGAHAIFAVTDWAGCYSRVAGDETLQSEAAKAGLSLEEYAGHLETLQGINLATAASDPNVLSTLERYVFSTLAPVKQISGGKYKNSYEFDSKAAAEQHIRDKLPELRARLSTVNMGIFQETWREISAFRPHKKPDGTFEYVRLKCDGPHKENPEVVASRDSGAFVEALVLHHPPGTDVLGASQIISKEDYAALWAKTQGVEATVRDVDEEEYVKYLPEGFDKTVLDDFRFFAEYGYAGGNPKVKTPEQLGIKTTSLEDYFRSEDWSAVLKGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9C7</accession>
    <name>W6Z9C7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_9813</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964179">
        <property type="protein sequence ID" value="EUC40281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693195.1">
        <property type="nucleotide sequence ID" value="XM_007695005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9C7"/>
    <dbReference type="GeneID" id="19129193"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9813"/>
    <dbReference type="eggNOG" id="ENOG502SI3E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006329_9_4_1"/>
    <dbReference type="OrthoDB" id="5121955at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="26"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="747" mass="83531" checksum="F3667CF4CEF0F285" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9L1</accession>
    <name>W6Z9L1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_92067</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686779.1">
        <property type="nucleotide sequence ID" value="XM_007688589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9L1"/>
    <dbReference type="STRING" id="930090.W6Z9L1"/>
    <dbReference type="GeneID" id="19127999"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92067"/>
    <dbReference type="eggNOG" id="KOG2588">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_622539_0_0_1"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11395">
        <property type="entry name" value="bHLHzip_SREBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="328"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="385"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="288"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="440" mass="47722" checksum="69330BDA10CA080B" modified="2014-04-16" version="1">MALNWDAFLNTDGFNLPNNQWSDPLPPTAAPRASQMPKSTTTDTSGSSPEDLNNFDPLIGASSADPYFDDSLFLSNDYFLGDLDVLKPFGNTAGGKSTTESSPEPTTSGNNPAAQAPVLLANGLDQSSHMSAAQRLALQRANTFPNPAYESMFPNSIDSGFVEDLTFPDGPEGPSVAAKPAVERNQPSTSTNTTSKRTKNKPDILSACWTSPLCPNHDQDGPPPNPSTCGGGCAPFLFADQDNLPSISDLLAEPQEVMAEDGIVEIQPRPKKRSESDASANGFSTRQFESKETTSSPTEDRHRTKSETTEDNSTKESPQGDDGKPKSRRRLPHNQVERKYRESLNTQLDSLKRVVPSLQQNPRGCDSADIEDLPAPSKPSKAVILASATAYIKQMEREKKSLADENQLLRTRVKALQALVKCDDCSLMQYVMDLKIKQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9P2</accession>
    <name>W6Z9P2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_35696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686767.1">
        <property type="nucleotide sequence ID" value="XM_007688577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9P2"/>
    <dbReference type="GeneID" id="19122846"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35696"/>
    <dbReference type="HOGENOM" id="CLU_1128973_0_0_1"/>
    <dbReference type="OrthoDB" id="10328290at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="208" mass="22558" checksum="B62C476EACC387B9" modified="2014-04-16" version="1">MADVMQLGRQASGVERGAHVECLSGVLRVDDWSWLATEPYKVLQRTDWTRICQSGPYALMALRSECQPVALVFPPSCTQPSFPSLTRLVASYQRHRMVLAARIDRRAAETLIGLSIPMDGSWARMGGEAALERILVSFTACSVRVTACAGFMLAPKPDILIPGAGAQEHGPDRCHKRVDLDVNPAVAVLPLLSPVLTSPLLTLGLADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9P9</accession>
    <name>W6Z9P9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_4420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963965">
        <property type="protein sequence ID" value="EUC46513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686938.1">
        <property type="nucleotide sequence ID" value="XM_007688748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9P9"/>
    <dbReference type="GeneID" id="19124227"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4420"/>
    <dbReference type="HOGENOM" id="CLU_2811954_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889835" description="Hydrophobin" evidence="1">
        <location>
            <begin position="20"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7045" checksum="F840480F8DAD3D7F" modified="2014-04-16" version="1">MKITTFLTTLVVLTPTVFARCLILGSGNGQTCPLTATVITCDLGSTPGLFSCKQIPQTTSYCCLTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9T6</accession>
    <name>W6Z9T6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Symplekin/Pta1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_98561</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
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                <person name="Han J."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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    </evidence>
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        <source>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000005">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010102">
        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01780">
        <property type="entry name" value="SSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00050387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00052698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="498" mass="53289" checksum="923DE28A3C99252F" modified="2014-04-16" version="1">MGHSVPPLNDKSLLKNQTYVNGEWIDAKSGKTFEVHDPATGKLIGTMPEMDRADTEAAIAAAAAALPSFRKTTGRERARMLQKWYQLMMDNAEDLAKLVTWENGKPIADAKGEVNYAASFYEWFAEEAPRIYGTTIPATVPGNRVFTIKEPVGVVGLITPWNFPAAMITRKIGPALAAGCTVVAKSPGETPFTAAALAELAHRAGIPKGVVNFVTALKNTPEVGETITSSKIIKKVSFTGSTGVGKLLMKQSSDTLKKLSFELGGNAPFIVFDDADLESAVAGAITSKFRSSGQTCVCANRIYVQSGIYDEFCTKFTEKVQSFKVGGGYDEGVTHGPLIHDRAVSKVDAHVQDAVKNGAKVLHGGQKLPDLGANFYQPTVLRDMTKDMQLARDETFGPVAGLFPFETEADVVKLANEADVGLAGYFFSRDIQRVYRVAEALEVGMVGVNTGLISDVASPFGGVKESGFGREGSHMGIDEYVVTKTITMGGNGQPLQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB48</accession>
    <name>W6ZB48_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1748-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_3917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686383.1">
        <property type="nucleotide sequence ID" value="XM_007688193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB48"/>
    <dbReference type="GeneID" id="19123628"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3917"/>
    <dbReference type="eggNOG" id="ENOG502S6Z8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151392_1_0_1"/>
    <dbReference type="OrthoDB" id="16824at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF1">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9358" checksum="B75D5B966666F185" modified="2014-04-16" version="1">MVVGSLLRIRLGKVAHYAFDAVLISAFLAGVRRSTGLTPSLKPDSFSENPSALKWFENYLWVGETVMDQSVALFGASSYFERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBF4</accession>
    <name>W6ZBF4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TOM13-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_97255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688685.1">
        <property type="nucleotide sequence ID" value="XM_007690495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBF4"/>
    <dbReference type="STRING" id="930090.W6ZBF4"/>
    <dbReference type="GeneID" id="19129022"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97255"/>
    <dbReference type="eggNOG" id="ENOG502SBHA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127808_0_0_1"/>
    <dbReference type="OrthoDB" id="5529571at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070096">
        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013262">
        <property type="entry name" value="OMP_MIM1/TOM13_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08219">
        <property type="entry name" value="TOM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="14719" checksum="2779AEBBC3D6DDA9" modified="2014-04-16" version="1">MTSPAPTPNTLTESGITIPSDSETYDANPDLSPSPASTSSTSSPLILYKPPTLWGLLRGAAINLLLPFVNGLMLGFGELVANEAAYRLGWSGTKIFPSHRLGSSTGRRVGPGVEMRADPVERRRRNGQELDMYTSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBT4</accession>
    <name>W6ZBT4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_35124</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686156.1">
        <property type="nucleotide sequence ID" value="XM_007687966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBT4"/>
    <dbReference type="STRING" id="930090.W6ZBT4"/>
    <dbReference type="GeneID" id="19122712"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35124"/>
    <dbReference type="eggNOG" id="KOG0245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001485_2_3_1"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinesin"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
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            <begin position="36"/>
            <end position="388"/>
        </location>
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        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
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        <location>
            <begin position="422"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="135"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
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        </source>
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        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="593" mass="66698" checksum="4FD96CAC1FC001EE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBW1</accession>
    <name>W6ZBW1_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
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        <name evidence="13" type="ORF">COCMIDRAFT_106766</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="143"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="402"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
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            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC41206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="571" mass="62863" checksum="553BBB69E4C9BF43" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC51</accession>
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        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_96804</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963993">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_96804"/>
    <dbReference type="eggNOG" id="ENOG502S48N">
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    <dbReference type="OrthoDB" id="1939603at2759"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="234"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50157"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC45014.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="398" mass="43409" checksum="81483D5DF9D82B1C" modified="2014-04-16" version="1">MDARQADYPQSGLPSPYPTFPEPVSEGTSADQASAAQYPPQGQDPRSSNLTPSSDYSLNPSSARSGSFPEYIQRSYQPAAQGQAPGGMAQQQSPSMPIPDGQANGHQSPQQLKSDSDVPIDPSIAAQTSPTYASHQQQYSPYTPHHDMQHYPGQPQTPMGYPSRPEWAGHYPQPGMHYGHPASSGPPAPAMVSPVQRPPTGGHPLSTVYSFVPIPGAQQHKRPRRRYEEIERMYKCGWNGCEKAYGTLNHLNAHVTMQSHGSKRTPEEFKEIRKEWKAKKKEEEAARKADEERHRADAQQRAHEGGAPEAPVYGQMRQSVGVPGQAPQHPQLPPIGYQPAASGNTAAPQYGTQSPGLPEGMAQYATPNSNAYNSPNSNSSSYPQSPYGQNPQMYQQNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCK6</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">COCMIDRAFT_3467</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
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    </dbReference>
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    </dbReference>
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            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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        <source>
            <dbReference type="EMBL" id="EUC49622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="116" mass="12951" checksum="0D2F033B374F23C0" modified="2014-04-16" version="1">MSSSTNLPLLFTLPPSNRHDFLLLDTSAKLSLKALNKQITSTIASSPNCAEFMAKHKAKDGPAEQIQEFKIHWDVKGREKLWPEYTVLTEDNISAVVELLKRNPGMGVLEVKMGKD</sequence>
</entry>
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    <accession>W6ZD10</accession>
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            <fullName evidence="6">MalT-like TPR region domain-containing protein</fullName>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
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                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">ATCC 44560</strain>
        </source>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR_19"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="11"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="176"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="374"/>
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        </location>
    </feature>
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        <location>
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            <end position="741"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="742"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1143" mass="126281" checksum="87CE6CF67A7CD870" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDC0</accession>
    <name>W6ZDC0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cobalamin-independent methionine synthase MetE C-terminal/archaeal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_24367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685665.1">
        <property type="nucleotide sequence ID" value="XM_007687475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDC0"/>
    <dbReference type="STRING" id="930090.W6ZDC0"/>
    <dbReference type="GeneID" id="19120579"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24367"/>
    <dbReference type="eggNOG" id="ENOG502QVN2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058877_0_0_1"/>
    <dbReference type="OrthoDB" id="7772923at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005085">
        <property type="entry name" value="PRK06520.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844:SF1">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="1">
        <location>
            <begin position="13"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="378" mass="42433" checksum="6FFC71772B24BAAD" modified="2014-04-16" version="1">MPLPSGVYRADHVGSFLRPKAVLEARTKVANGEITAEELRKVEDEHIAHVAKQQIDNGLLSITDGEFRRAYFHLDFLKNVAGIEERGQVGNIRHKDGFSPPTLVVTGKLGHPKAIQVDDFKFLEQAIKDNGSLATTKVCIPSPTMVHFRGGRASIDISAYPDLDVFFDDLARVYQEELDSLYQAGCRFVQLDDTNLAYLCDPDMRKAAETERNEDLSTLPRKYAELINKAIEKRPADMKIGIHLCRGNYRSKWFASGGYEPVAEVLFKELNVDAYFLEYDDARSGDFSPLRHLPEHKVVVLGVMSSKKNTLDDKEEIIKRLHEAAKITPKGLDQLCVSHQCGFSSTAEGNELTEEEQWAKVRLNVEIAKAVWGDDISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDU9</accession>
    <name>W6ZDU9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_88101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685357.1">
        <property type="nucleotide sequence ID" value="XM_007687167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDU9"/>
    <dbReference type="STRING" id="930090.W6ZDU9"/>
    <dbReference type="GeneID" id="19127200"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88101"/>
    <dbReference type="eggNOG" id="KOG3041">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070130_0_0_1"/>
    <dbReference type="OrthoDB" id="10249920at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080042">
        <property type="term" value="F:ADP-glucose pyrophosphohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080041">
        <property type="term" value="F:ADP-ribose pyrophosphohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019693">
        <property type="term" value="P:ribose phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03424">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5_UGPPase_Nudt14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF18">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="137"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC48160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="337" mass="37687" checksum="F2C375D93DF73F13" modified="2014-04-16" version="1">MRVEIHNPNERPSTRSPAALTLREFNGKTLDPPVPVYLPWNLTAQEFTQILDSPSDKPAFKFPALRNWLLGLLGTLDAQKDESHPFHRQPYRLEELTIESVDWFDKKNYTRLGYMKIQSEIRNGSGDGDWIPGSAFLRGGSVAILAIVQPTEASGEAEKHVILTVQPRLAVSSLAFTEIPAGMLDDSGSFTGTAAQELKEEAHLHVKIEELLDLSELALEQGQADSLAPTGQLRTAMYPSPGGCDEFMKLYLYQKRLSRAHMEWLKDRATGLENEGERIRLKLVPLENFWREAAHDGKALSALALYENLKRQGRIPDMPEEPAEEPKMQSCGVQAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE17</accession>
    <name>W6ZE17_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_83089</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683475.1">
        <property type="nucleotide sequence ID" value="XM_007685285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE17"/>
    <dbReference type="STRING" id="930090.W6ZE17"/>
    <dbReference type="GeneID" id="19126184"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83089"/>
    <dbReference type="eggNOG" id="KOG1716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023312_0_2_1"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14518">
        <property type="entry name" value="DSP_fungal_YVH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000104">
        <property type="entry name" value="Dual specificity phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016278">
        <property type="entry name" value="DUSP12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848:SF4">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000941">
        <property type="entry name" value="DUSP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="7">
        <location>
            <begin position="5"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="8">
        <location>
            <begin position="68"/>
            <end position="125"/>
        </location>
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            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="5">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR000941-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="324" mass="36015" checksum="9C5812894B22ADDF" modified="2014-04-16" version="1">MALLDRVPGNLNLYIGGIFTLRRREALEQANITHVLSVLRTPLDDVLFAPFKHMVVEVDDVDDENLLQHFPATNRFIREGLDAGGGVLVHCAMGKSRSATVVIAYLMQQHNISPSEALSHVRQARSICEPNPGFMDQLNLYAQMHTPPDVETTPVYQRWVYQREIELSRACGQAPDADKIRFEDEHVADEAAAFELRCRKCRRALATSQYLLSHGSSSTAKDNEAEVPTSAKCAHYFLDPLSWMRPELEQGKLDGRLECPKCHTNVGKYAWQGMQCSCGDWVVPGISLAKGRIDEARKATFGIRRPPGASGPPAVGDSHPKQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE60</accession>
    <name>W6ZE60_COCMI</name>
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        <recommendedName>
            <fullName evidence="12">Bms1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="13" type="ORF">COCMIDRAFT_8519</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. BMS1 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC41806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693470.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZE60"/>
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    <dbReference type="eggNOG" id="KOG1951">
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0032040">
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
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        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
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        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="12">
        <location>
            <begin position="63"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="402"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="572"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="636"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1121"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="427"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
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            <begin position="465"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
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            <end position="526"/>
        </location>
    </feature>
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        <location>
            <begin position="577"/>
            <end position="591"/>
        </location>
    </feature>
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            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
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            <end position="670"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="1168"/>
            <end position="1177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC41806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1177" mass="133642" checksum="57599DCD2A422834" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE91</accession>
    <name>W6ZE91_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_34414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687138.1"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48193.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="383" mass="43515" checksum="CA1656085F1ECE66" modified="2014-04-16" version="1">MAIYTLADLHMPSRRSSSIPRQYHRMAAAGQQDHRFSLADAANLKPKLQALDKALTSTCVGHGRELDFTSIDDAVNIQPPHVAVYVDGSEEFFLMVKTISRPDLIPKVLAEAIKTMSYGRPHVNIQRASDFRKGADPTFSDFRPMLPDIDRLCGTDLAGAVARLEAQGKLRLRLQVYSYVLPEHPRGILPPWCRKNNGRRLALMRVNKQLHSEVRKHYYENVNFLIATVFQLENTSLYEDNTIALRHLIESMDSNTFPLIKQLSVRINGSTVQESLRTGPPSPPFALKYIFDTFTGLEKLTITFGAAPRSNMWAGQDVESIHRKYMEQMKTRFIKYIPPSIKVSWWHEDAARFFNSDIVEKSLWTAIQERASTCTDESVDTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEA4</accession>
    <name>W6ZEA4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_87541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685183.1">
        <property type="nucleotide sequence ID" value="XM_007686993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEA4"/>
    <dbReference type="STRING" id="930090.W6ZEA4"/>
    <dbReference type="GeneID" id="19127088"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87541"/>
    <dbReference type="eggNOG" id="ENOG502SP48">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057546_1_3_1"/>
    <dbReference type="OrthoDB" id="449382at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF1">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="1">
        <location>
            <begin position="160"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="334" mass="36977" checksum="D7D37E1D1BC14760" modified="2014-04-16" version="1">MSNEPPQPLPNPPFYIIPNINNLRDASISLTTTSGSRIRPGVLFRSAEVSKLDLAGWTAVHSLGISHVFDLRSKPEVDKGWAGIVGKDASGDDDVRPGWLQAMEQAGVAREWVPVFEESDYSPERLAERYSKYMDEAVTGFVEAYRDILANGGPAFAKILSYLAAIPLSSSVEDDGGKKVGALVHCTAGKDRTGIFFGLLFEFLGVPREQIAEEYQLTELGLAHIREEVVGRLMQSPGFKKYMLARMQGTKLSVEDIARSLKGEEGQDQVQVPPEVLEKGRQAALRMIGARKESMFRSLEMLDEEFGGVERYLREKCGLGDQELDALRRNLLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEN4</accession>
    <name>W6ZEN4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_8392</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964078">
        <property type="protein sequence ID" value="EUC41986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691504.1">
        <property type="nucleotide sequence ID" value="XM_007693314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEN4"/>
    <dbReference type="GeneID" id="19126360"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8392"/>
    <dbReference type="eggNOG" id="KOG2182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1304661_0_0_1"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886949" description="Carboxylesterase type B domain-containing protein" evidence="6">
        <location>
            <begin position="21"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="23242" checksum="F5CD2EF0B4F9AA9D" modified="2014-04-16" version="1">MARHSLRCFQAAFLAHFAVSVVIRAEQDSKHFALNYTSNSACNLPVPLPIPKDPTLKQYGKGTFRQPLHHKAPELGNFTVNYYWNSTFWAGSGSPIVVFLPGEVKADRHLVFSRPDFSLVGIIPENLRAAVIVPEHRYYGGSSLFSELTTSNLSYLTVENALLDIVNLANHFDPPWTDASSTAQDVPWILTGGSYSGAQTAWIANVFGGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF26</accession>
    <name>W6ZF26_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Stress response RCI peptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_39773</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964072">
        <property type="protein sequence ID" value="EUC42116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691352.1">
        <property type="nucleotide sequence ID" value="XM_007693162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF26"/>
    <dbReference type="STRING" id="930090.W6ZF26"/>
    <dbReference type="GeneID" id="19123749"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39773"/>
    <dbReference type="eggNOG" id="KOG1773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107649_4_1_1"/>
    <dbReference type="OrthoDB" id="2802411at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF112">
        <property type="entry name" value="PROTEIN SNA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9462" checksum="42B33B2B53D2B8C0" modified="2014-04-16" version="1">MPSSTRSICLYFLAIWLPFLPVLMLRGCGADVLINIALDLLGWIPGVIHAWYIISQNEKREYVHVEPGYGRGHGYREKRVKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF46</accession>
    <name>W6ZF46_COCMI</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_86661</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZF46"/>
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            <begin position="1"/>
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        </location>
    </feature>
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            <begin position="190"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="245"/>
            <end position="333"/>
        </location>
    </feature>
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            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="407" mass="45139" checksum="F8812B527327FAA6" modified="2014-04-16" version="1">MPGPYTFSPSHTRGDSRNSCFDSTRRYSLASETTGRQVIDSDAHETRKRSRYGDSTAPGSWSDYPLNNNRFIHNKSPPPLANDRYELAGGMDGPQTFGRRDGDYDDYFNLQSQRGTWSVPPTPQVGLSTQAAAGEMHTTPNGSKAWSLISLVGGVAGKLFEFCTVPFRGFQAGSGQKYNIESNADVAEKLGLHDDPYNPGPVQQPTPGSFPRDDYGIQPFPSITPERPRLAKRLRTTDNWVMVGADCETESRPGTPRLSERRLPGHSHGRSPSSQIPRPVSRANLSTPSQKRPSLIPVSRRSTTDRRSLHSPAPSLSKFSPGTPASSRSYTTRLSYGSPTSFFEKNNSVASPLPQESQRLIDKVRKEEMEEDERMRRMSLQMSAMLKEANEALGAKFEVEMFDDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFV6</accession>
    <name>W6ZFV6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684536.1">
        <property type="nucleotide sequence ID" value="XM_007686346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFV6"/>
    <dbReference type="GeneID" id="19126752"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85858"/>
    <dbReference type="HOGENOM" id="CLU_2305570_0_0_1"/>
    <dbReference type="OrthoDB" id="3688469at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="100" mass="10555" checksum="A8B39673060A20DE" modified="2014-04-16" version="1">MTMPNQSSLILRGTIASETTPVDATPDQKTNAGPNQANSGAWSAASANSKHGYKLSADEHALRDRCQESLVGATQSTCVTNNGFEPQVTQNQGLARHSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG56</accession>
    <name>W6ZG56_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GmrSD restriction endonucleases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_39437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964059">
        <property type="protein sequence ID" value="EUC42486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690974.1">
        <property type="nucleotide sequence ID" value="XM_007692784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG56"/>
    <dbReference type="STRING" id="930090.W6ZG56"/>
    <dbReference type="GeneID" id="19123689"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39437"/>
    <dbReference type="eggNOG" id="ENOG502S229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019571_0_0_1"/>
    <dbReference type="OrthoDB" id="5419821at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="GmrSD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639:SF1">
        <property type="entry name" value="DUF262 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="GmrSD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GmrSD restriction endonucleases N-terminal" evidence="2">
        <location>
            <begin position="68"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="551" mass="61434" checksum="FA5A2B821799BD38" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGC6</accession>
    <name>W6ZGC6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_2198</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684478.1">
        <property type="nucleotide sequence ID" value="XM_007686288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGC6"/>
    <dbReference type="GeneID" id="19120155"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2198"/>
    <dbReference type="eggNOG" id="ENOG502T48Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1440934_0_0_1"/>
    <dbReference type="OrthoDB" id="67965at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="188" mass="20036" checksum="A8E6FF96F64098EB" modified="2014-04-16" version="1">MGWFSSDEKSVLATHPVNLDVTTKSGSGAEQDRYAQHFSSDAIKRGVDRGLDKLQNAANAAGSGAEQDRYASHLSIGDRGHRAIKEAAKYQGDGAEQDRYNAHFSPALHSYDAVKAVQAAGSVVANGEKNASWYGLGYDGRQRAKLMAGSGMGAEQERLGSHFGLSKDSVANAAQRVKDGAQDVLPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGS2</accession>
    <name>W6ZGS2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HhH-GPD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_31619</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682345.1">
        <property type="nucleotide sequence ID" value="XM_007684155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGS2"/>
    <dbReference type="STRING" id="930090.W6ZGS2"/>
    <dbReference type="GeneID" id="19121908"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31619"/>
    <dbReference type="eggNOG" id="KOG4161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053907_1_1_1"/>
    <dbReference type="OrthoDB" id="10265068at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045138">
        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074:SF0">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN PROTEIN 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074">
        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC51057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="29321" checksum="F95387B2893AD723" modified="2014-04-16" version="1">MPVVTRSRRIRPSNQTHGEGASQHAPLPQKKKHSSPTKTRLDKQNHPRIIPQPSGLSLTLQPAKYGLIQERICDSLYALVVQAILWNQTRGQMARPVLFELLSAYPSPNELSVAPLHDLINMLQPIGLHRIRAIRLIALADAWLAAPPCRQRRYRRLHYPDRGCGTNVRPGEVLGPDDEREGWEIAHLPGMGAYALDSYRIFYRDRLRGTEGVVGIEPEWKRVVPTDKELKPYLKWRWEQEEQETPHLGSSIVEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHA1</accession>
    <name>W6ZHA1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phenylacetate 2-hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_7585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964045">
        <property type="protein sequence ID" value="EUC42921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690555.1">
        <property type="nucleotide sequence ID" value="XM_007692365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHA1"/>
    <dbReference type="STRING" id="930090.W6ZHA1"/>
    <dbReference type="GeneID" id="19125326"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7585"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_4_1"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF9">
        <property type="entry name" value="P450, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="61592" checksum="5B3E24827C585436" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHF2</accession>
    <name>W6ZHF2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Xylose isomerase-like TIM barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964043">
        <property type="protein sequence ID" value="EUC42981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690503.1">
        <property type="nucleotide sequence ID" value="XM_007692313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHF2"/>
    <dbReference type="STRING" id="930090.W6ZHF2"/>
    <dbReference type="GeneID" id="19123600"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39027"/>
    <dbReference type="eggNOG" id="ENOG502S1RE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035063_0_0_1"/>
    <dbReference type="OrthoDB" id="5360893at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050312">
        <property type="entry name" value="IolE/XylAMocC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110">
        <property type="entry name" value="HYDROXYPYRUVATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12110:SF21">
        <property type="entry name" value="XYLOSE ISOMERASE-LIKE TIM BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="1">
        <location>
            <begin position="27"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="369" mass="41948" checksum="85ED6E9417370EB7" modified="2014-04-16" version="1">MPCRLGISSMSLGRSYAGHSLQHKLSMAKKHGIEGIELFFEDLVDHAGSDSPSALLAGAASVRGLCSSLGLEIICLQPFMHYEGLVDRKRHEERVEEMKLWIKLAKVLQTDIIQVPSSFLPEDQVTSDMELIVSDLREIADLGLQESPVMRFAYESLGWGTRVNKWEECWDVVTRVDRPNFGICLDSFNILARIYADPTSETRKTPDAEKEVRESMQRLVERIKPHKEKIFFVQVVDAERLAQPLVRGHEFYNVEQPARMSWSRNCRLFYGETSRGAYLPVREVVHAIFKEVGYDGWVSMELFNRIMNSTDHAVVEELAERAAESWRKLQQDLGFIGGVSPGSQKLANLHSKKGQETKNVIQEIEVARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHH4</accession>
    <name>W6ZHH4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dopa 4,5-dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_31446</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682137.1">
        <property type="nucleotide sequence ID" value="XM_007683947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHH4"/>
    <dbReference type="GeneID" id="19121870"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31446"/>
    <dbReference type="eggNOG" id="ENOG502S93P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090062_0_1_1"/>
    <dbReference type="OrthoDB" id="9970095at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1240">
        <property type="entry name" value="DOPA-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023389">
        <property type="entry name" value="DOPA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014980">
        <property type="entry name" value="DOPA_dioxygen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423:SF2">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08883">
        <property type="entry name" value="DOPA_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143410">
        <property type="entry name" value="DOPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC51307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="20118" checksum="489220687C7CF177" modified="2014-04-16" version="1">MADPSIYEYESPLKGFENCEPLPNEKAEDGKSYVNPPADKASDAYNSFVAPITNGIRGGFDVHIYYLQSDEEETKFANELWERIRREFPELRIYRVWDRPIGPHPLAMFEVNIFTPQQFGAFIPWLVINRGPLSALIHPNTDEEERDHTQRATWMGQPLPLNLKIFKKRAAPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHL9</accession>
    <name>W6ZHL9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_1741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683940.1">
        <property type="nucleotide sequence ID" value="XM_007685750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHL9"/>
    <dbReference type="STRING" id="930090.W6ZHL9"/>
    <dbReference type="GeneID" id="19119935"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1741"/>
    <dbReference type="eggNOG" id="ENOG502S0H8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038193_2_0_1"/>
    <dbReference type="OrthoDB" id="5598852at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF59">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="75"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="373" mass="41847" checksum="8B4EFA03FD2F102C" modified="2014-04-16" version="1">MASQGFWGRFNLRNEDGKSCMRAIQNAYIGYRVKELEQQGYCSCTLLVAPLSGTEHSTIVDKDLAEEFEGRSTRSELIVQLRPAPHALDLDIVHVAAKIYPSLAPTVALLDVELPEGLKAYEMDRIPGTSLSRLMPHARTLTTKEQARLETLVLSFAKFIAQGWQGASKAQTLPTLRATRADSPMEDTPDILSQCRGKVGSSIIYRLEKLAAELPDTYLRRRAGKTLSAIQNMTDYPVILNHGDLIPSNILVDGDRWEMTGLVDWAEAEFLPFGTCLYGLEHLLGYYERDSSSKKSAWVYFEGAARLREAFWEYLFAAAPGLKAREDEVRTMRDMGVLLWHGIAWDDGAINRVVSELRDQEELVKLRAFLGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI58</accession>
    <name>W6ZI58_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_84009</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683776.1">
        <property type="nucleotide sequence ID" value="XM_007685586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI58"/>
    <dbReference type="STRING" id="930090.W6ZI58"/>
    <dbReference type="GeneID" id="19126376"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84009"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_1_1"/>
    <dbReference type="OrthoDB" id="256333at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="21"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC49658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="373" mass="40036" checksum="EFD3C4233D83F084" modified="2014-04-16" version="1">MMSPHTIPSNMRAAVIEEFKKPYRFREIPTPTEPTGRDLLVKVLAASYCHTDAVLVEGKMSQDLPRIGCHEFAGRVVASGPDVSKDLHIAIGDEVGVPGRAYHPCGACNECTLDHDDPVGYSPYCPTAKNLGLTMDGGFCEYALVDSRQVAPIPEGMTALEAAPLMCAGLTIWSALDRVKEATTIAIIGAGGGLGHLGVQFSAHLGKRTVAVDRGEKPLKLLKNVIDRMDPSTPGSTVLVDSLVHNPKDVVQDVIGGGVEAVIFLPESQAAFDYGMQLLRNHGTIVVVSFPDELIFSAKDLVFRDIKVIGSLVGRNHQLRQMLNFAAKHKIKAVTTLYALEDLNELANQHRAGMGGKLVVDMNQAGNSGKPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI72</accession>
    <name>W6ZI72_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_90851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686346.1">
        <property type="nucleotide sequence ID" value="XM_007688156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI72"/>
    <dbReference type="STRING" id="930090.W6ZI72"/>
    <dbReference type="GeneID" id="19127768"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90851"/>
    <dbReference type="eggNOG" id="KOG0806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_2_0_1"/>
    <dbReference type="OrthoDB" id="412018at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07197">
        <property type="entry name" value="nitrilase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050345">
        <property type="entry name" value="Aliph_Amidase/BUP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674:SF16">
        <property type="entry name" value="CARBON-NITROGEN FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G02350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="300" mass="33094" checksum="83B2B3B49D38ED42" modified="2014-04-16" version="1">MAPIVKVAVIQLYPKPLQPEHNFNKAEALIRSAAAQGAELAVLPEYHLTNWKPKDPEFLAVVEKCSDYVKKYQQLAKECGICIVPGTIVESHKENEKEQDRLLNVCYFINHQGNIIGKYIKKNLWGPERDHLTGSGRDVHEVFDTPVGKVGLLICWDLAFPEAFRELIAQGAKIIIIPTFWTLNDCNEAGLKQNPAAEALFLNSILTARAFENTCAIIFANAGGPPGKGYAGLSQVTVPFVGPLTKLGGAAEGMSVVDIDMQVLEDAEANYQVRADLAKDDWHYDYRHGKGPLGRGKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIH1</accession>
    <name>W6ZIH1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Altered inheritance of mitochondria protein 24, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_32815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AIM24 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683644.1">
        <property type="nucleotide sequence ID" value="XM_007685454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIH1"/>
    <dbReference type="GeneID" id="19122184"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32815"/>
    <dbReference type="eggNOG" id="ENOG502RXC5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046558_0_0_1"/>
    <dbReference type="OrthoDB" id="5295771at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.160.10:FF:000001">
        <property type="entry name" value="Altered inheritance of mitochondria protein 24, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959:SF2">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC49800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="381" mass="41301" checksum="B789A1E65EEEB95A" modified="2014-04-16" version="1">MLRSAASPWANLARTCAPAGRSSIAARCINISATSPSPEPSLQQAVSVEGTATPMHTPDARFDVIGTPFSLLSVSLSASQTLYTRRGTLVGLSGKSENTLSTLSVLEPFQRAPVGIPFLYQKVSSTSPVTALISTKTPISSIVSVNLDGRDDWIISQKQALLAWTGLTLKLKPQYNVKLGLAHWGNTYITGRGLLALTGNGQIYQVHVKAGESYVAHPSNVVAYTASNTPPVPFRFKSSNVRFQVPDLGFGSLVQNTQFFRTMSKTATWRALATTYHTLKTWMRRTVWGDRLFLRFEGPTTMLVQSRASRISDVLTLRDVDEIADSPPGAVEDAVTRKIKEEIKSIGEQGTKAPIPNTDASGTVRYATIKDGKAEFEKPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIR9</accession>
    <name>W6ZIR9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683538.1">
        <property type="nucleotide sequence ID" value="XM_007685348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIR9"/>
    <dbReference type="GeneID" id="19126242"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83393"/>
    <dbReference type="HOGENOM" id="CLU_2922279_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889859" evidence="1">
        <location>
            <begin position="20"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="61" mass="7116" checksum="8316EB446F4B4522" modified="2014-04-16" version="1">MSGIGAALLAYLLFKESLWLKRYSGQEEWVAARFFFLPVDRRQRSWCYYLGAGTSDLFRAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIY4</accession>
    <name>W6ZIY4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Choline monooxygenase, chloroplastic</fullName>
            <ecNumber evidence="5">1.14.15.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_83356</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the first step of the osmoprotectant glycine betaine synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>choline + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = betaine aldehyde hydrate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:17769"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15870"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.14.15.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (monooxygenase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the choline monooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.7" evidence="5"/>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683579.1">
        <property type="nucleotide sequence ID" value="XM_007685389.1"/>
    </dbReference>
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    <proteinExistence type="inferred from homology"/>
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        <source>
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        <source>
            <dbReference type="PROSITE" id="PS51296"/>
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            <dbReference type="EMBL" id="EUC49953.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="448" mass="51686" checksum="62D5513F63069A5F" modified="2014-04-16" version="1">MADGAVAERVGKSSTSVAPEGHLQSDYYPNMVGGLLSYLGFGGAAAQTPPENEPVRALPANWYTSEEMYQLERRAIFTRRWLILTHKSRLANPGDFLRYNIANYDVVVSKDRSGEINAFHNVCRHRAYPVVEKDGGNAKIFSCKYHGWSYGLNGNLAKAPGYQELQNFDKAKNGLFPIHTRIDRNGFVWINMDSKKVPEVSWESQFDHVDEQTRFDQFNFDDYEFDHTWNLEGPFNWKILADNFNECYHCKSTHPDLTTGLVDLESYDVYCKADHIQHDPKTPQYRKDLGQEICSTYCFPNASFTVTQHFLFMQKFMPKSPTESVMYYEVWRNKHSSEEDFLLISDTYKRVMGEDKVLCERAQKNIEAGIFINGELHPRMEKGPLFFQKRCREIVMEHGMREKKAGHKIWPAKQQLDSEAGSLLTKEMEDFCEGLSCGTDNEKSDLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ70</accession>
    <name>W6ZJ70_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="5" type="ORF">COCMIDRAFT_1272</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963926">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF54">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
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        <property type="entry name" value="LRR_14"/>
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    </dbReference>
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        <property type="match status" value="3"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="4">
        <location>
            <begin position="92"/>
            <end position="168"/>
        </location>
    </feature>
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        <location>
            <begin position="219"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="614"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
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        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="919" mass="101745" checksum="D8F01A0094373859" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK28</accession>
    <name>W6ZK28_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">Amidohydrolase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_89175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZK28"/>
    <dbReference type="GeneID" id="19127421"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89175"/>
    <dbReference type="eggNOG" id="ENOG502S2A5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009942_6_1_1"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887153" description="Amidohydrolase 3 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase 3" evidence="2">
        <location>
            <begin position="80"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="643" mass="68577" checksum="0F61B54F2C56625A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKB3</accession>
    <name>W6ZKB3_COCMI</name>
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            <fullName evidence="6">Annexin</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_89035</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKB3"/>
    <dbReference type="GeneID" id="19127394"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89035"/>
    <dbReference type="eggNOG" id="KOG0819">
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    </dbReference>
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    <dbReference type="OrthoDB" id="2134400at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
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        <property type="match status" value="4"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
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        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF107">
        <property type="entry name" value="ANNEXIN ANXC4 (AFU_ORTHOLOGUE AFUA_3G07020)"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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            <end position="357"/>
        </location>
    </feature>
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        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="139"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="701" mass="77998" checksum="52400B19233A6D4A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM47</accession>
    <name>W6ZM47_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycoside hydrolase family 16 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_31701</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682375.1">
        <property type="nucleotide sequence ID" value="XM_007684185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM47"/>
    <dbReference type="GeneID" id="19121940"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31701"/>
    <dbReference type="HOGENOM" id="CLU_826361_0_0_1"/>
    <dbReference type="OrthoDB" id="3791536at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887591" description="Glycoside hydrolase family 16 protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="36855" checksum="CD23AB0E2539945B" modified="2014-04-16" version="1">MELRIAALVSAIAYFTFANAEVAPEITTVAEGYNVIAKVPCVECPFLYQDTSKGNDAPWTQRKDANALLLNISLPYDSAHLSINNAALLTNNKILPRIYANQVLEDISTDDVATLISSNQLDNLGGSYFGASYSYTLARVKDEPKALLFQFDIMELWTDLTSPPLTVFVDGEKQKIVEVVLMQRPLLSPGDPAGAYEIIKVHLVERPPAQTKSTKGPRKVSMWFHDWDTNGKKGTATHIVNSASESFVNYISSGVWALFVFVIAVIALFVLVCLFVIFGCGWWNENDYEIAQHGKKNKSSGSGGRAKDVEAARRFLSPEELGLRGSGRVIGVGKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM86</accession>
    <name>W6ZM86_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_338</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682304.1">
        <property type="nucleotide sequence ID" value="XM_007684114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM86"/>
    <dbReference type="STRING" id="930090.W6ZM86"/>
    <dbReference type="GeneID" id="19122409"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_338"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009666_3_1_1"/>
    <dbReference type="OrthoDB" id="6718656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048315">
        <property type="term" value="P:conidium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="APSES transcription factor (MbpA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000291">
        <property type="entry name" value="APSES transcription factor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF15">
        <property type="entry name" value="TRANSCRIPTION FACTOR MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0183">Conidiation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
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        <location>
            <begin position="9"/>
            <end position="115"/>
        </location>
    </feature>
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        <location>
            <begin position="266"/>
            <end position="298"/>
        </location>
    </feature>
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        <location>
            <begin position="387"/>
            <end position="419"/>
        </location>
    </feature>
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        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="502"/>
            <end position="550"/>
        </location>
    </feature>
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            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC51123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="692" mass="77518" checksum="23DB9623D486B1B1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMF2</accession>
    <name>W6ZMF2_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_21262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AN11006-like"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
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        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
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        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC51275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="423" mass="48800" checksum="8960E151E3C856DD" modified="2014-04-16" version="1">MVDKAKTPDPSSPATRRDRDSSPELGSPSKATTVYNKRTGRPIRRSAGKMKKPDGYVSFEADDGDLATTEESEDEEDEDEDMEPRGRANKKKRKRGPSLPSPRLEPIIYNQELDEMTDIEEGVRHDLKKPPPITLQFNVPLGFHGPLFVKLDRTLLDSQQDAVHEMMPAKSKKARLASLEPTKTVSVRTDPDMDTGTHRPKGFTDLPPELRNNIYRRLFAQKEPDQMLKIPSVKGSGTSGSLARSSQFLRTCKLVHSEGCSILYGENTYSFHRHYATRAPFWDTVPKEIGYQDVLHFLKMIGPENLQYLRDIKWVFDDACPRDTPYLTSNEQRRYLNDEYLINCLRILRDAKLRKVTLFFGGRRQLQCSDHRFLGYLEQIKADDVVQSADRWYSYREKVHPLVWTELKATMTRKKKLYEKEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMH0</accession>
    <name>W6ZMH0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_80233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682470.1">
        <property type="nucleotide sequence ID" value="XM_007684280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMH0"/>
    <dbReference type="STRING" id="930090.W6ZMH0"/>
    <dbReference type="GeneID" id="19125629"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80233"/>
    <dbReference type="eggNOG" id="ENOG502RXTJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044092_0_0_1"/>
    <dbReference type="OrthoDB" id="674948at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40129">
        <property type="entry name" value="KETOPANTOATE REDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40129:SF2">
        <property type="entry name" value="KETOPANTOATE REDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC51178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="31974" checksum="8F66DC7A6E880383" modified="2014-04-16" version="1">MLRQQMNEVDLLILGAGWTSTFLIPQLGDTDITYAATTTSGRDDTIPFKFDPESGDAELYKRLPAAKTVLITFPLVGHGQSKSLVGLYRSIHGAKNNWIQLGSTGIYNKVPDDWSDEDAHYNKEDRRAIAEDELRSLHGCVLCLAGLYGGERVPARWLPRIVKSKDDIKKRGAVHFIHGEDVAQAIIATHQNFTPGKRWIVSDMRVYDWYDLIMSFSSMTESSMSQEEKMTQQQYAKWVGELMMEEEIRALPRDVGSLGRKLDSRRFWAHHGLLPRHRRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQK2</accession>
    <name>W6ZQK2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Translation initiation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_94043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687545.1">
        <property type="nucleotide sequence ID" value="XM_007689355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQK2"/>
    <dbReference type="STRING" id="930090.W6ZQK2"/>
    <dbReference type="GeneID" id="19128375"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94043"/>
    <dbReference type="eggNOG" id="KOG2317">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_7_0_1"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.40:FF:000038">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803:SF58">
        <property type="entry name" value="PROTEIN HMF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887027" description="Translation initiation inhibitor" evidence="2">
        <location>
            <begin position="21"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="15809" checksum="7C67FA07454825CA" modified="2014-04-16" version="1">MVSFKSIFTTFLVVAGAAIATPSPKLAQQPVVTYLGTQGPILSSGAWTSKGIVYTSGTVPSLNGTIVPGGIKAQTAQVIKNIAAVLEEAGTSWDYVMKTTVFLANMSDYTAMNEVYAAMLPSPKPARTAVEVGKLPGNFLIEVEAIAAIPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZR79</accession>
    <name>W6ZR79_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_82824</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683430.1">
        <property type="nucleotide sequence ID" value="XM_007685240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZR79"/>
    <dbReference type="SMR" id="W6ZR79"/>
    <dbReference type="STRING" id="930090.W6ZR79"/>
    <dbReference type="GeneID" id="19126135"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82824"/>
    <dbReference type="eggNOG" id="ENOG502S5AR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_3_6_1"/>
    <dbReference type="OrthoDB" id="406544at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF30">
        <property type="entry name" value="DUF636 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03180)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="2"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="132" mass="14579" checksum="8FF50B7D2F01B38D" modified="2014-04-16" version="1">MPTGGCMCGNVRYEVQGDMEAQILCHCYDCRKISGTTYSTNALQSKDGFKILQGTPKEHKKTADSGSNITSFFCGDCGSTMWRESDSYTGKMIIKVGTLDDHSILDNFSTKIELFTKNRPKWVGTQEGAAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRF5</accession>
    <name>W6ZRF5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687219.1">
        <property type="nucleotide sequence ID" value="XM_007689029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRF5"/>
    <dbReference type="GeneID" id="19122940"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36108"/>
    <dbReference type="eggNOG" id="ENOG502RYBJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022878_0_1_1"/>
    <dbReference type="OrthoDB" id="271448at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890177" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="31387" checksum="80BF3F71F921CF23" modified="2014-04-16" version="1">MSPLQQLLIVGAAVSTVLAAPVIPNAEPACEPLPHGHGLIPRPDTAEAFQSFPAFSLAATSATTPVGYIQAYSNLVTTFNEPSQFLRYFNLGSYDVNKCAAECGKDDKCNIFGVFFERTPMYKPGPKCPNPSSSTMIKCTLWSGTMSPKTGINNGQTREQFRIVMAGSNAYVKDITFSNKKDGSSNILKNWVVEKYQNGAAIQVPLDCNGVDTYMGMAAWRDGKFDAQRCLDACKVAGDTDIQSRKCRFVNTYVQRRNGVQVAQHCAMFSEYWPAPFATNLGQRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRF6</accession>
    <name>W6ZRF6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_83096</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683466.1">
        <property type="nucleotide sequence ID" value="XM_007685276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRF6"/>
    <dbReference type="STRING" id="930090.W6ZRF6"/>
    <dbReference type="GeneID" id="19126186"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83096"/>
    <dbReference type="eggNOG" id="KOG1239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029282_1_2_1"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF65">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC50089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="334" mass="37229" checksum="2520406321F2677C" modified="2014-04-16" version="1">MLPSCSLRHPACQLLRRNVLVSRASPCRPSARSFHASTPRQDPIIDAILYLPHEMISLIHTAVPWYAAIPLSAFVARGLLVTTAGTRARALMARYIGLHPLRQALAFQKRDEILKRGNFRSPQQALVTVKKEVKDVTSTLDKRWNVSLSGQISWTLAQIPIFFAMAETIRQKCGAQDGLLGMTMSIFRGESTRMTTETGEVVARVTPTDWFEPTLATEGMLWFPDLLLPDPTGALPFIASGIMFANIYTSKNTVESGAKWPNVLRRTLLFVSLLVGPLCQNLPAALMLYWSSSTASVMLWNAWLDRKYPAPRGYTACKRPLLLPPTPISRLRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVF1</accession>
    <name>W6ZVF1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anaphase-promoting complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_3362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685736.1">
        <property type="nucleotide sequence ID" value="XM_007687546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZVF1"/>
    <dbReference type="STRING" id="930090.W6ZVF1"/>
    <dbReference type="GeneID" id="19122365"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3362"/>
    <dbReference type="eggNOG" id="KOG4322">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010478_0_0_1"/>
    <dbReference type="OrthoDB" id="2504561at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037679">
        <property type="entry name" value="Apc5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026000">
        <property type="entry name" value="Apc5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12830">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12830:SF9">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12862">
        <property type="entry name" value="ANAPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 5" evidence="7">
        <location>
            <begin position="264"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="788" mass="87891" checksum="4549F56D1F036E11" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZW48</accession>
    <name>W6ZW48_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein mgr2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_3006</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGR2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685380.1">
        <property type="nucleotide sequence ID" value="XM_007687190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZW48"/>
    <dbReference type="STRING" id="930090.W6ZW48"/>
    <dbReference type="GeneID" id="19121610"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3006"/>
    <dbReference type="eggNOG" id="KOG4096">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142435_3_0_1"/>
    <dbReference type="OrthoDB" id="5409308at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018450">
        <property type="entry name" value="Romo1/Mgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525:SF1">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10247">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01378">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12391" checksum="9FC7DCF044A80980" modified="2014-04-16" version="1">MPVPVGSMPQGAHGPSTLDKLKMGGMMGGSVGLIIGFIFGFTNIVRFGPGPNGMLRTLGQYMMGSAATFGFFMAIGTTIRTESSPIATQAFNSASRRPMILPRSFQYPRVARNEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX35</accession>
    <name>W6ZX35_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transcription factor Nrm1/Whi5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_87231</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685051.1">
        <property type="nucleotide sequence ID" value="XM_007686861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX35"/>
    <dbReference type="GeneID" id="19127013"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87231"/>
    <dbReference type="eggNOG" id="ENOG502RZ4H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025591_0_0_1"/>
    <dbReference type="OrthoDB" id="2163387at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40468:SF1">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40468">
        <property type="entry name" value="YALI0A15257P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="90"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="265"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="282"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="42466" checksum="E8B4D9FD8AA32D53" modified="2014-04-16" version="1">MAEQDDVATKVLRRAQVSKMTRTLQNRLALANVKMKNGWESLSLDAIEPVLDGVERKRKRPGSSNEAMSDVSSVSERFYQPSVLDSSPLQAPIFSDHIRRSESRSAGSYTQTKRPRCQRPSSNKYPASSNHARVKVRTSTSAATSWKNSFQLPESSPVYHRRHARFGRQHVPSLSFVSETSTVADPHSPLLSEDDDEDLPIMSFSLNRSHFQSSPPRAPRTPPPDVARSARLRQRGFNAAGAAREGKHGDDDANLLMYLATSPTPVRPGHQKPQMLAPSTPPSKSTPLPSSMMSTPGGGGSHYTGFGLATPSTNLNFAEFLNMSPSPAQANASWNRTPVATRTPAAVREARRHINFDNIVPPTGDAAHMRAHIGKMDGLSMELGGELIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W7A038</accession>
    <name>W7A038_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HAD superfamily hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_33210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684077.1">
        <property type="nucleotide sequence ID" value="XM_007685887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A038"/>
    <dbReference type="STRING" id="930090.W7A038"/>
    <dbReference type="GeneID" id="19122269"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33210"/>
    <dbReference type="eggNOG" id="ENOG502QR7R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_11_1_1"/>
    <dbReference type="OrthoDB" id="426235at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033883">
        <property type="term" value="F:pyridoxal phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01427">
        <property type="entry name" value="HAD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885:SF1">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13290)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="25339" checksum="22BFD6669E58F4A4" modified="2014-04-16" version="1">MAQRPRRFAPLDPAKRKEGDQRPELKGIVFDVDGTLCLPQNYMFAEMRAALGIEKPTDILDHVYSLPESEQEEAQEKIRNIERTAMKSQQPQAGLVELMEYLDSRGVKKGICTRNFDAPVAHLLTTFLPKSKFSPIVTREFRPPKPDPAGILHIAKDWMHEDGGNSLIMVGDSIDDMTAGHRAGAATVLLVNEVNNHLSEHEYTDLVVKRLDDLIPILESGFEGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2W7</accession>
    <name>W7A2W7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Carbohydrate esterase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_32431</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683174.1">
        <property type="nucleotide sequence ID" value="XM_007684984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2W7"/>
    <dbReference type="GeneID" id="19122104"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32431"/>
    <dbReference type="eggNOG" id="ENOG502S2CW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021264_11_3_1"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF4">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890196" evidence="10">
        <location>
            <begin position="20"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="71"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="12">
        <location>
            <begin position="149"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="401"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="472"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="364"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="420"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="491"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC50341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="517" mass="53766" checksum="603F060DA062BB98" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3L3</accession>
    <name>W7A3L3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_57157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682913.1">
        <property type="nucleotide sequence ID" value="XM_007684723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3L3"/>
    <dbReference type="STRING" id="930090.W7A3L3"/>
    <dbReference type="GeneID" id="19124713"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_57157"/>
    <dbReference type="HOGENOM" id="CLU_000288_138_5_1"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF11">
        <property type="entry name" value="HET-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8835" checksum="50DCAE209573AE55" modified="2014-04-16" version="1" fragment="single">MRLLRRSSTGDFCLTKDLIGDDTIPPYAILSHTWEADTEVTFADMINGTGKGKLGYRKIQFCGEQARQDDLQYFWID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W7A424</accession>
    <name>W7A424_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_81208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682762.1">
        <property type="nucleotide sequence ID" value="XM_007684572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A424"/>
    <dbReference type="STRING" id="930090.W7A424"/>
    <dbReference type="GeneID" id="19125822"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81208"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028281_6_0_1"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887399" description="SET domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="130"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="418" mass="46277" checksum="2AA63018C2D70CBC" modified="2014-04-16" version="1">MNSLRVFFALSGTCAAATTSHIHGPSSSPQCANLPSHFAAQMQTPLRSQQCLHGDTDAKPPPVIPSFKHPIWSHEPICVTGKEKVYCIHTTSDSGSGHGLSIIATPSAAGKLSAKFSKQQKKKRGKHSEDGLQVRSIPGKGKGLFTTKVIKKGETILLDPARIIASSHFPARVSHAQGRRLFNSALDRLPEEDHKMVAALDQSLGGSPIEDVMKTNSFACRLDDGNMDKAYICLFPSVSRINHACQPNALARFVSKTLSMQVKAKRDIAIGEEINISYGRVDLTREERQELYKDGWNFECTCSLCTAPHGETKASDDRRVRFARLKQKLQNLTAETYDAKKVVEWEKEVMAIAQSEGLEVLLAEDYERLAYVYAGHGMASEARRWAEMAKQNLLDWAVEDSRRDDDVRRLDETLAELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4D3</accession>
    <name>W7A4D3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_80690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682619.1">
        <property type="nucleotide sequence ID" value="XM_007684429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A4D3"/>
    <dbReference type="GeneID" id="19125709"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80690"/>
    <dbReference type="HOGENOM" id="CLU_1895825_0_0_1"/>
    <dbReference type="OrthoDB" id="10495579at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="134" mass="15065" checksum="C3D5A26B5E4F46E2" modified="2014-04-16" version="1">MSVGSEKCVVTAQTNQKNAASKEARETQAGKSNRSVVSIYTMDRLFSIEAERQYNTSLGFAECWRKKGYPGFHKVDSNYQSITTITRVNLAVQCTNFLHVKERQKRNHNCKLGSTVRRLSAPSLFTCLSVRGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJE4</accession>
    <name>W6YJE4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_41962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964389">
        <property type="protein sequence ID" value="EUC39492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693988.1">
        <property type="nucleotide sequence ID" value="XM_007695798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YJE4"/>
    <dbReference type="STRING" id="930090.W6YJE4"/>
    <dbReference type="GeneID" id="19124163"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41962"/>
    <dbReference type="eggNOG" id="ENOG502S0ZE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024263_0_1_1"/>
    <dbReference type="OrthoDB" id="3357002at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021460">
        <property type="entry name" value="DUF3112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184">
        <property type="entry name" value="YALI0C10208P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11309">
        <property type="entry name" value="DUF3112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="342" mass="38886" checksum="52CFE072C0127603" modified="2014-04-16" version="1">MSIQSRSGPLRPTGWALGGIPKKNVDIPVTVVFLFLYIIGAATHMTIFQYNKRRGHKFLFNGALFGFCMTRITTCTIRIASISLPANIHLAIAAQIFVAAGILLIFVINLLWSQRILRAYHPLGWHPFIGYMLTAIYVVIVLTLVMLITSIVQSFYTLHPRTHQIDRDIQLYGSTFFAIISFLPIPLVAIALILGKASSGRKVEKFGQGRHRTKIAVLLLGATLCCLGASYRAGTLWLHPVSMHEPEPARFYRGWFYFMNFGLEILIIYMYAIMRVDLRFWIPDGAKGPGSYRMKHEWEEEHARTRLSDKESLRETERKKNKQRGAQANRLPKQIGRAPLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YKK8</accession>
    <name>W6YKK8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Homing endonuclease LAGLIDADG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_41819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964272">
        <property type="protein sequence ID" value="EUC39707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693766.1">
        <property type="nucleotide sequence ID" value="XM_007695576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YKK8"/>
    <dbReference type="GeneID" id="19124135"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41819"/>
    <dbReference type="eggNOG" id="ENOG502SQ50">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1073552_0_0_1"/>
    <dbReference type="OrthoDB" id="5405897at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051289">
        <property type="entry name" value="LAGLIDADG_Endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181">
        <property type="entry name" value="INTRON-ENCODED ENDONUCLEASE AI3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181:SF1">
        <property type="entry name" value="LAGLIDADG ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00961">
        <property type="entry name" value="LAGLIDADG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homing endonuclease LAGLIDADG" evidence="1">
        <location>
            <begin position="117"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="226" mass="25811" checksum="3811A0CDE663B8BA" modified="2014-04-16" version="1">MLNLNRSKTLFNYNLNIAKAIPVEDIKKSLNDYKVKNNIEVFKNNNNLGHYLAGVTTLNRVLNPRIVFTSHINNLGMYAFIQSELGNIGRFQASGNNAIRYIIGDIKGIMLFINLMHGFTESDGHFGIKYLERKTKSDTRKRSVSESVTLKFILNKRLFDKPTSSSMKPFMEDLALFLSCNLKSYINNTNSEILTVSVSSLESVKFLVNYFNKYPLIGDKLNDFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6YND7</accession>
    <name>W6YND7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_107726</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964135">
        <property type="protein sequence ID" value="EUC40847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692624.1">
        <property type="nucleotide sequence ID" value="XM_007694434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YND7"/>
    <dbReference type="STRING" id="930090.W6YND7"/>
    <dbReference type="GeneID" id="19119106"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107726"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_0_5_1"/>
    <dbReference type="OrthoDB" id="3689213at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF11">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Condensation" evidence="7">
        <location>
            <begin position="134"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="589"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC40847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1079" mass="117433" checksum="3399D3A868B6F776" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNN2</accession>
    <name>W6YNN2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_107458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964128">
        <property type="protein sequence ID" value="EUC40972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692526.1">
        <property type="nucleotide sequence ID" value="XM_007694336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNN2"/>
    <dbReference type="GeneID" id="19119051"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107458"/>
    <dbReference type="HOGENOM" id="CLU_1630989_0_0_1"/>
    <dbReference type="OrthoDB" id="3691014at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="145" mass="16388" checksum="A693777709C37DD4" modified="2014-04-16" version="1">MSVSIATQAFCLTNLTHSVSTLSHLFPLLNLSHLRAVCRNVLSINLNRRRIHAYVHAMIAVSCPLNIGVTGGCRKTHTHRARTLSYTISRICMPGDTPTNCQSPKMARRTFGRLDSCMSRFEMCFVVDNDEVLRRSLPMYHPWIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPX2</accession>
    <name>W6YPX2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_106137</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964102">
        <property type="protein sequence ID" value="EUC41437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692036.1">
        <property type="nucleotide sequence ID" value="XM_007693846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPX2"/>
    <dbReference type="STRING" id="930090.W6YPX2"/>
    <dbReference type="GeneID" id="19118808"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106137"/>
    <dbReference type="eggNOG" id="KOG1502">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="350" mass="38334" checksum="44D025D4DCA5C63E" modified="2014-04-16" version="1">MALLDNPAIASGSTVLVTGANGFVGAHVADQLLHRGYKVRGTVRDAAKHQWLAQLFSQKYGAEKFELVTVKDMREPGAFDDAVSGVSAIAHVASVRSMDVTPDELLRTTVAGTLACLQAAANEPSVQRFVLTSSSAAVRSIQAYRGTDTVLSGEYDNHTLSVARSMPANFPPMQKFMTAYFASKVAAEQAFWNWIKDNKPHFTANTVLPCTIYGSPLDVVHQGFPSTSKIPLQILDGDTDSIKHVQRFYYIHVQDVARLHVAGLIHPDTANERIFAYASPYSINEFFDIFVKFVRDYRPPGKLPGLDFPLAVIGPWQRAEALLKDLGHPGFVGLEETIVDNVQTRIKTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQG6</accession>
    <name>W6YQG6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear speckle splicing regulatory protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_10110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NSRP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964227">
        <property type="protein sequence ID" value="EUC39900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693584.1">
        <property type="nucleotide sequence ID" value="XM_007695394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQG6"/>
    <dbReference type="STRING" id="930090.W6YQG6"/>
    <dbReference type="GeneID" id="19117805"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10110"/>
    <dbReference type="eggNOG" id="KOG2117">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042321_0_0_1"/>
    <dbReference type="OrthoDB" id="446635at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053246">
        <property type="entry name" value="NS_splicing_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018612">
        <property type="entry name" value="NSRP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845:SF1">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09745">
        <property type="entry name" value="NSRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear speckle splicing regulatory protein 1 N-terminal" evidence="4">
        <location>
            <begin position="112"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="181"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="309"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="181"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC39900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="414" mass="45528" checksum="AE5C01AB93A85AF6" modified="2014-04-16" version="1">MSFKFGLNVKAKGNNPLAKAGAKPGIGTKKKPLFGDDEDDDVKGKAKAVDGVQEIGELSFEDTLASASSEPSKSAPAKQKKGQPPAPPSKKPKPKEDDPTNVAYSASAAEAEKRAQEALEADATIYDYDAAYDAIHARDAEKAAADREDAAQRKPKYMDALFESAEQRKKDQLRARDKLLQREREAEGDEYADKEKFVTGAYKAQQEETRKAEEEEKKRLEEEEDMKKKLGMQGFHKQMLAERERRHQEAMEAAARALKEGVKLPAEETEKEKTDAEIAEELRKQGKKVVLNDDGQVADHRQLLSAGLNVIAKPKPTSTASASSSAATAAPKYTPSHGIHKGGRNAQRERQTAMIAEQIEAANKRKAEEEAEEQAKIERARKSQKTDQDISSAKERYLQRKREAAAAKAAASGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR97</accession>
    <name>W6YR97_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_41571</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964206">
        <property type="protein sequence ID" value="EUC40028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693447.1">
        <property type="nucleotide sequence ID" value="XM_007695257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR97"/>
    <dbReference type="GeneID" id="19124084"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41571"/>
    <dbReference type="eggNOG" id="ENOG502RZ6G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011910_1_0_1"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053230">
        <property type="entry name" value="Trans_reg_galc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47654:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47654">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="327"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="650" mass="71715" checksum="E5F3370E42D99FC3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRN5</accession>
    <name>W6YRN5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xaa-Pro dipeptidyl-peptidase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_109222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964179">
        <property type="protein sequence ID" value="EUC40280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693194.1">
        <property type="nucleotide sequence ID" value="XM_007695004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRN5"/>
    <dbReference type="STRING" id="930090.W6YRN5"/>
    <dbReference type="ESTHER" id="cocmi-w6yrn5">
        <property type="family name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="GeneID" id="19119388"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109222"/>
    <dbReference type="eggNOG" id="ENOG502RMBN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048587_1_0_1"/>
    <dbReference type="OrthoDB" id="2498029at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050261">
        <property type="entry name" value="FrsA_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946:SF9">
        <property type="entry name" value="POLYKETIDE TRANSFERASE AF380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase-like" evidence="2">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="269" mass="29020" checksum="48B9B82BAA7023B7" modified="2014-04-16" version="1">MGHGIGAVKGAGLPQFATAFAEQGYAAVVFDYLHWGQSDGEPRGDLVVSRELQDFKDVIAWVRLQPERFDNQRIVAWGSSFGGMHVTALMAQDHDLRAGIAQCPCVDGTASSLMLPLVYSLRLGLTAMADAIGSLFGAKPIYVNLTGDDTPGAPLSLMRGPEAVSGFKNIEPIDGTTLSNAITARSVLQVLAIRPVRHIHKSTKPYLLVLPTWDHQASLTAAERAVQEAPLGEALRVEGGHFDLYPNAPAYQRNLAGQLQFLKRVFSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRN9</accession>
    <name>W6YRN9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_8239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964072">
        <property type="protein sequence ID" value="EUC42117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691340.1">
        <property type="nucleotide sequence ID" value="XM_007693150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRN9"/>
    <dbReference type="GeneID" id="19126040"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8239"/>
    <dbReference type="eggNOG" id="ENOG502R1A4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041184_0_0_1"/>
    <dbReference type="OrthoDB" id="3786670at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="403" mass="44520" checksum="63886354DE2CF2AE" modified="2014-04-16" version="1">MWRTGLLYLDRGDSSILNALRNAGYDTQNQPTSPSRTPRRFSMASDTESALEGKLKHDIKAQQGVQHWVMPSDVNGLKFASSPRASPRTRAIDPADALGLATDATLFEEPVLYSLDRIKEDNHNPDYFAYHDLQKSPSLKGDCDEPVHVHKRRPSHLRTPSTPTIESRLASAQKASRSLPLRAKTNEGLLQLQANTSKPQRSANTHQRRISLGLPIKAANAPGETSRLSSPTNTRSLHPATPKRLPKKTGTATAIQQERDLEYKHRHTFIGTASLDDFLEVLDVSPDHITNKDAIIRAFILLASSERLLARQASLKPDGWSVIARTSAETVNSDYVEQAHAKLGSIVLRQFLDLITFNEDEEANAMSVVEAFTAASHLDTQASKASGSKAKAFRKWMVKALPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS13</accession>
    <name>W6YS13_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_8186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964069">
        <property type="protein sequence ID" value="EUC42227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691258.1">
        <property type="nucleotide sequence ID" value="XM_007693068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS13"/>
    <dbReference type="STRING" id="930090.W6YS13"/>
    <dbReference type="GeneID" id="19125943"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8186"/>
    <dbReference type="eggNOG" id="ENOG502SC13">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060131_6_5_1"/>
    <dbReference type="OrthoDB" id="2115692at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF14">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="62"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="217" mass="24523" checksum="52145CD90EEEC356" modified="2014-04-16" version="1">MPLEVHRITSPDDFETFAKIQVAAFASGGGIASLLNPEPVTDEYIKKYTERHLKSWRDEHDVVYLKVVDTDIDGGKMIAGAKWRITEKEKTEEEAQKMYPKPEGDDLNNQALVDFLAFLYRARKQYVNTKPICFLQILITDPEHHRRGAGSLLLKWGLSKADELGLQGFLEASPMGKPLYERMGFKTQETAVFDLTKYGGEGEDANTIMIREPSPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT59</accession>
    <name>W6YT59_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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        </source>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Han J."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Schackwitz W."/>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964106">
        <property type="protein sequence ID" value="EUC41373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUZ1"/>
    <dbReference type="STRING" id="930090.W6YUZ1"/>
    <dbReference type="GeneID" id="19123879"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40447"/>
    <dbReference type="eggNOG" id="KOG2444">
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    <dbReference type="HOGENOM" id="CLU_280054_0_0_1"/>
    <dbReference type="OrthoDB" id="2288928at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
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        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF80">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="72"/>
            <end position="113"/>
        </location>
    </feature>
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        <location>
            <begin position="555"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1125" mass="124090" checksum="60ACDEEB3FB1398F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV13</accession>
    <name>W6YV13_COCMI</name>
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        </submittedName>
    </protein>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="77" mass="8461" checksum="0AE4778D6B3EA776" modified="2014-04-16" version="1" fragment="single">VETHVCASDGRRPGSRVGTAGRRADSNAPSSALDGQHRENCVSKHLILFNSEFCRFPFIARIGTVLNMCTPCRWSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVN4</accession>
    <name>W6YVN4_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_100669</name>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_100669"/>
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    <dbReference type="OrthoDB" id="630188at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
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    </dbReference>
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        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF0">
        <property type="entry name" value="CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="337" mass="36913" checksum="254C9FA064604C1D" modified="2014-04-16" version="1">MPKRSICHISGSSSESKDSEKRVRIDCDRPLLTPVRFLILSDTHGANLPSSLPPCDVLFHCGDLTEDGTPESIFAAIRNLSKVKAKLRLVIAGNHDISLDKEYWVSQGGAESDSEIVQALFNPECGASKHGIIFLSEGIHTLNLPCGAVFKIYASPYTPGCGTSAFQYPTGSDRFNPPETTPLWAKNVGTETSIIPENVDIVMTHGPPKYILGETAGDSAGCEHLRNAIVRVKPRLHCFGHIHLPREGWTYQAHRLAYKDPPKPDSGEPGLIATIFKDWVGSNQARKKGFRCLPPGSAEDFRASKQQTLCVNAAMEGEKGELEHPPWLVTLDLPVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVU6</accession>
    <name>W6YVU6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_105545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964092">
        <property type="protein sequence ID" value="EUC41653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691825.1">
        <property type="nucleotide sequence ID" value="XM_007693635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVU6"/>
    <dbReference type="GeneID" id="19118705"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105545"/>
    <dbReference type="HOGENOM" id="CLU_1669068_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="158" mass="17854" checksum="C826FD1FD14B04CB" modified="2014-04-16" version="1">MFCFSEWRLELRLCPATTLMHSAVEKARFGSSLANGHGDYHSVRSSRLVSVDRSTSMRFEFLASCTLFGRSVAPRSLPTSLSLFDSPHVRFQLPAISRRPSQTRCETLDIQGLYTLRLLLDSPMLFCDCDLYCLCIERLVSLVFVQCTPGLLRFAAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW00</accession>
    <name>W6YW00_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HlyIII-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_40166</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ADIPOR family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964090">
        <property type="protein sequence ID" value="EUC41708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691783.1">
        <property type="nucleotide sequence ID" value="XM_007693593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW00"/>
    <dbReference type="GeneID" id="19123827"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40166"/>
    <dbReference type="eggNOG" id="KOG0748">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023075_2_0_1"/>
    <dbReference type="OrthoDB" id="529367at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF52">
        <property type="entry name" value="ADIPONECTIN RECEPTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="35039" checksum="652F345DA2E088AA" modified="2014-04-16" version="1">MERIRIYFLNQLDLFKPELYRAYVRKRLEIWLRITHNLSSRLVPRRDNEYILSGYRAVSWSYKRSLESILGIHNETVNIFSHIIGSIIFFTLPMPIYRSLQPRYTTATTADVVVFSTFFFGVAICFALSAIFHIFNNHSQNLGIVILMWGSTIPCVYYGFFCTPHLQKTYYTLVSILAAGCVYATLHPAFRCPKYRPYRAAMYAGLGLSFVIPIIHGIIIFGWETQMWRMSLDWMALMTAFNLVGAALYAMRIPEKWYPYRFDVWGASHQIMHCLVVCAGIAHLYGLLRAFDHVHGHGDACTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWN8</accession>
    <name>W6YWN8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Aquaporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_38308</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964019">
        <property type="protein sequence ID" value="EUC43792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689689.1">
        <property type="nucleotide sequence ID" value="XM_007691499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWN8"/>
    <dbReference type="STRING" id="930090.W6YWN8"/>
    <dbReference type="GeneID" id="19123442"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38308"/>
    <dbReference type="eggNOG" id="KOG0223">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020019_1_7_1"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1080.10:FF:000014">
        <property type="entry name" value="Aquaporin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="7"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC43792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="39949" checksum="9682C7CFA4600663" modified="2014-04-16" version="1">MALENILPFHKNDIPPSQSHPGAPQNEPQDSHPDSSHGRHPHIEAITHGHKGARVRTTIISHNWHNRSVAALAEFAGTFMFLFFAFGGTSVANNSNQANRSNSNSDSDEILQVPDTSVLLYISLVFGFSLMINVWCFFRVSGGLFNPAVTLGLYLIGSVPLPRAIMCFVAQMLAGIAAAGVVHAIAPGPLSVSTTLSARMSPARGVFLEMFLTSLLVFTVFMLAAEKHKATFLAPVGIGMALFVAEMLGVFFTGGSLNPARSFGPCVITGDFPGYHYIYWFGPIMGSLLACGVYKVVKAVDYETVNPGQDFDDHEAAAFQCPDNPHSRDQVWRPIVSRQLMRRGTHESEESAGEKTIERLDTNQTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWR9</accession>
    <name>W6YWR9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_8375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964078">
        <property type="protein sequence ID" value="EUC41968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691495.1">
        <property type="nucleotide sequence ID" value="XM_007693305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWR9"/>
    <dbReference type="GeneID" id="19126318"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8375"/>
    <dbReference type="HOGENOM" id="CLU_1142425_0_0_1"/>
    <dbReference type="OrthoDB" id="3922633at2759"/>
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        </location>
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        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="243" mass="26765" checksum="56E82BD39DE5FD3A" modified="2014-04-16" version="1">MRNQHQEEQCSQSMAYAMQPHSGFSSNPPLTSLPRTNIPRSQNPYAYAGSYGLDPGLMNLNYRSMTPALNNSMPLGVQASHSFEGQGPPNSGYYQPSNSPAHPQSNRHCQTAQQGQQRGGLVNPHNLGRTRNRRPSQSSSLNSEEGQSQREFHFPPLQESSHEAQSEGIRSGASQLHRSCAANIHDGQSFEVPPLPENHKQRIADEQVRFERCVSGSISGNPTRSRTCLDAPSPDLNSPQRPQ</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="GeneID" id="19123420"/>
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    </dbReference>
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        <property type="entry name" value="CELL SURFACE PROTEIN"/>
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    </dbReference>
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    </dbReference>
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            <end position="153"/>
        </location>
    </feature>
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        <location>
            <begin position="244"/>
            <end position="320"/>
        </location>
    </feature>
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        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
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    </feature>
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        </location>
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            <end position="140"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="320" mass="33779" checksum="AA1E586D109FCB67" modified="2014-04-16" version="1">MTGAHSGSSLGDTIRKGVHMVHGTGEAIRGNAMSMVDEASGDKASAVKNQEIANKGVDEWDRGYRGHATSAGVAPTNNTSTSTNYGPHDSNIGNKLDPRFDSDTDHRGTATGSTNAGPHSTNMGNKLDPRFDSDQDHRADPTSTIGADLHTFPPIQQTDGTEIHGPDPPHEYRGSIGALSGLEAANKLDPIFPVGPDAESMKYTDHANIHRLRGSISGASGLQAAQKLDPPTFEPAHASDVVLARGPGLNQPDPSHYHPKPTYKSNVAKSLDRDVGIKETQQPDSASTRSRANPIEQIAGSDTTKGETGSTSNTQKTEPR</sequence>
</entry>
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    <accession>W6YX44</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_41530</name>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="111" mass="12589" checksum="39E858B1C3908939" modified="2014-04-16" version="1">MCWSFELILDDPDVQKKLLKSLRSFHTAAVTEYRLPTHSEICDASIPYLDAVVEESLRLEDTVVLGHCIPEGIHIMMRHPENMVSERGMRRAWTCSILSGGLCLRIMAESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXC7</accession>
    <name>W6YXC7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_9894</name>
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964189">
        <property type="protein sequence ID" value="EUC40184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693300.1">
        <property type="nucleotide sequence ID" value="XM_007695110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXC7"/>
    <dbReference type="GeneID" id="19129361"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9894"/>
    <dbReference type="eggNOG" id="KOG1192">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1219514_0_0_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF27">
        <property type="entry name" value="GLUCOSYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="227" mass="24959" checksum="B3595936510DDE3D" modified="2014-04-16" version="1">MHHLDPTSKKDEEADLGLAGKNLRTSATAKAFLILHHLFGWPILTLKTTTVSTSLLVRKTLLFNAFEALGTELKPYCHRIRIATHDVVKNFVRESDLKSFLSMLIRMRMCCSLGTVLMVMLRPSSKSIQANNVSNIVIQARLWSAHHGGAGIMACGLLNACPTSIIQFLEDQPFWDDVVAAADTGPRPVPHASLTEKSFTVIIETLLDPNIERSAKDIAAICDAGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY14</accession>
    <name>W6YY14_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isochorismatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_37874</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689226.1">
        <property type="nucleotide sequence ID" value="XM_007691036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY14"/>
    <dbReference type="STRING" id="930090.W6YY14"/>
    <dbReference type="GeneID" id="19123341"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37874"/>
    <dbReference type="eggNOG" id="KOG3346">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_573619_0_0_1"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF9">
        <property type="entry name" value="FAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="4">
        <location>
            <begin position="76"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="428"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="476" mass="52677" checksum="75B02CD5885F98E5" modified="2014-04-16" version="1">MAPESLTVTTTQESHDITIGTIKCTASIPFGGEGQWLYLPATKKFDLSRGAERKMVLECDEERSNHTGLMIDPGKSVLIVVDMQNYFVHPLYRDHAAGITAIDPTLKVIERCRKEGIQVAWLNWGITDHDLNKMAPAIQRGFSKTLGWHVGLGAQLPGGQGRCLFKRTWNAALYGPFQAVAQPGDLFFDKTRMSGLWSEKEPIHEYLRASGKQTLLFAGVNTDQCVFGTVSDAYSYGWDCVLLSDCTGTMTGRGAQELAEYQISQNMGFVVDSDTFCNAPIDDHVEIIDDFLPSLTLSIVWSDAKAKLGNTIDPEDLQEQPTAILHDDTSPDGKHAGSGMSYVITLTDPDAPSRDNPEWSEFCHWIASNVSIVQDTFSVLPSPEFGLTEEIESTEELHDVMGYKPPGPPPKTGKHRYVFLVFAPKNGTTEPLHPSKPQGRKHWGTGKERGGVREWAQENELVPVAANFIYSENEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY28</accession>
    <name>W6YY28_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioester reductase (TE) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_103437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964060">
        <property type="protein sequence ID" value="EUC42485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691025.1">
        <property type="nucleotide sequence ID" value="XM_007692835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY28"/>
    <dbReference type="STRING" id="930090.W6YY28"/>
    <dbReference type="GeneID" id="19118300"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103437"/>
    <dbReference type="eggNOG" id="ENOG502S9F2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_990419_0_0_1"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioester reductase (TE)" evidence="3">
        <location>
            <begin position="33"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC42485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="281" mass="30921" checksum="D63633488721CE99" modified="2014-04-16" version="1">MNAKQPFSAFLPQFRVLRSLIDFAALISAHSSSDSKVVFQFISSIATVGHYPIHEGTPHIPEQRVIIEHVLPNGYGDAKYVCERMLDETLHKHSSRFSVMAVRLGQVAGCSASGYWNENEHLPFLIKSSQTLRALPKFEGPVSWTPVDAVAAVCADLALGASTAGGIYHIDNPVRQPWSKMLPLLASELGIPEKNIISFKEWIKRVRSFSHEATPGNADLNPAKRLVDFLEADFTRMSCGGVLLGTERSQKDSAAMRGVGSVDDEVVRRYIGSWKARGFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY72</accession>
    <name>W6YY72_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_6355</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964007">
        <property type="protein sequence ID" value="EUC44282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689171.1">
        <property type="nucleotide sequence ID" value="XM_007690981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY72"/>
    <dbReference type="STRING" id="930090.W6YY72"/>
    <dbReference type="GeneID" id="19124936"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6355"/>
    <dbReference type="eggNOG" id="KOG0207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_0_2_1"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000068">
        <property type="entry name" value="Copper resistance-associated P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000043">
        <property type="entry name" value="Copper-transporting ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00003">
        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF32">
        <property type="entry name" value="COPPER RESISTANCE P-TYPE ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0186">Copper</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="624"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="667"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1045"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1106"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="17">
        <location>
            <begin position="73"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="17">
        <location>
            <begin position="162"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="851"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="852"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC44282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1149" mass="123616" checksum="2B37E3D6DF5820E0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ60</accession>
    <name>W6YZ60_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_28563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964046">
        <property type="protein sequence ID" value="EUC42880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690593.1">
        <property type="nucleotide sequence ID" value="XM_007692403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ60"/>
    <dbReference type="GeneID" id="19121329"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28563"/>
    <dbReference type="eggNOG" id="ENOG502S5KX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073370_0_0_1"/>
    <dbReference type="OrthoDB" id="4948898at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20242">
        <property type="entry name" value="PFM_aerolysin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.15.10">
        <property type="entry name" value="Proaerolysin, chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053237">
        <property type="entry name" value="Natterin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39244:SF5">
        <property type="entry name" value="NATTERIN-3-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39244">
        <property type="entry name" value="NATTERIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56973">
        <property type="entry name" value="Aerolisin/ETX pore-forming domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="326" mass="36483" checksum="E8B2C3C432F21AB4" modified="2014-04-16" version="1">MASKPLIPSPDLRVRIINTESRLALYSNARDKLGLNHVDISIPYRDQYWYVRPGQGKNAGLYLIVSDYNDRAIYVDFENGLQWGPAGTSAPAGSSDLQYFDLAQQQGKGIRAGQFRIYNPTNDGVLFSRTNQQYEIGCVSNAMGTFNDQWFTFEAEPLELINIEFDLKNTVTESVRPVNIHSQEATNDTSEPQTPLIEVLKTTEQQYTFESEVGLELGISTKFSSGIPVAAKAEVKISAKIHTNLSWGIANSHSQTWKSSVPLNVPGHKTYKVTMTVTEYTIRVPFKAKWKSPATKKTIVTEGVFKGINSSELKTNYYEVHKTKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ73</accession>
    <name>W6YZ73_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FUN14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_102372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FUN14 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964046">
        <property type="protein sequence ID" value="EUC42895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690613.1">
        <property type="nucleotide sequence ID" value="XM_007692423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ73"/>
    <dbReference type="STRING" id="930090.W6YZ73"/>
    <dbReference type="GeneID" id="19118068"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102372"/>
    <dbReference type="eggNOG" id="ENOG502SEUQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106353_1_1_1"/>
    <dbReference type="OrthoDB" id="3990500at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007014">
        <property type="entry name" value="FUN14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04930">
        <property type="entry name" value="FUN14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886268" description="FUN14 domain-containing protein" evidence="6">
        <location>
            <begin position="27"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17457" checksum="EFBDEA9E0D84D26F" modified="2014-04-16" version="1">MSFILPGLRRGLMLSTPLILSTPLLAYQFRNAQRIRCDGPDPITKITNDLKSNYAAEARTPIITQSGAVNPRAIQQISMGSILGVIGGLGISVFSKPLAILIGLGIFAVQFIESRGIHIVPYSFLQRRLKSMNVRSLVQDNVAFKLSFGLTFAMAAFAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZF8</accession>
    <name>W6YZF8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DUF1640 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_37520</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CCDC90 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688796.1">
        <property type="nucleotide sequence ID" value="XM_007690606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZF8"/>
    <dbReference type="STRING" id="930090.W6YZF8"/>
    <dbReference type="GeneID" id="19123263"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37520"/>
    <dbReference type="eggNOG" id="KOG3156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063283_0_0_1"/>
    <dbReference type="OrthoDB" id="889336at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000018">
        <property type="entry name" value="Mitochondrial protein FMP32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024461">
        <property type="entry name" value="CCDC90-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360:SF1">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07798">
        <property type="entry name" value="CCDC90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="31218" checksum="0725A9D4EDC3F311" modified="2014-04-16" version="1">MAAPSVSAAAIPRFLAPRLQWSASSSWPAAQSTIEARRHGSCWAASEGRMPLSKLSPLQTAGTRQWQQQRWSQRTSGHGSALELQRSFSASAKQAKDHHFDTLKFVQRLKEEGFTEEQAEGMMRVLSDVIEESIQNLTRTMVLREDQEKATYTQKVDFAKLRSELMTADSTESSLTRASHERLTNELAKLNSRLRDEIQRTQASVRLDLNLEKGRIREEANVQELKLKETDTRIEQETAQLRERLEAVKFSTLQWLMGVCTGTAALMLGVWRLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZK5</accession>
    <name>W6YZK5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_30195</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964128">
        <property type="protein sequence ID" value="EUC40969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692512.1">
        <property type="nucleotide sequence ID" value="XM_007694322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZK5"/>
    <dbReference type="GeneID" id="19121635"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30195"/>
    <dbReference type="eggNOG" id="ENOG502S13F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038839_2_0_1"/>
    <dbReference type="OrthoDB" id="5422068at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="8"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC40969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="371" mass="40982" checksum="FF94A925004176AE" modified="2014-04-16" version="1">MADDTITLTASCLCKAHVHTTTVPESSLPLKAHICHCDTCRHVSGSLYSSLAFWPSPRSTVDLSGYKLFNFSPAFDLLFCATCSTPMIGAFKDETKPLLMATGALNNFACDVEVVKWSHMGFIGDTKDGGASVWIKYINASGPPLKCFKTETRGNSAEELAVDWQLQLKSPDTITDRQDAIPIRCKCRGIDLVLNRGNYNHVATDYLPWNVDPASRKLKTELCGCDSCRLHTGNDVFYWTFADLQHISFPLSADENEFPSNMQDLAALVDGKDGRIGSLVYYESSPGVHRYSCNTCSTTIFYTTSTRPRFIDVAVGTLEAKDGARAESILAWQFDYGVGHKEDGAGGWREGLFERIEKSLKEYGHTRSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZW6</accession>
    <name>W6YZW6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_38881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964038">
        <property type="protein sequence ID" value="EUC43150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690330.1">
        <property type="nucleotide sequence ID" value="XM_007692140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZW6"/>
    <dbReference type="GeneID" id="19123572"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38881"/>
    <dbReference type="HOGENOM" id="CLU_112522_0_0_1"/>
    <dbReference type="OrthoDB" id="3679329at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="233" mass="25716" checksum="B8FDF6805FA3FF61" modified="2014-04-16" version="1">MRASIAIIATITSQIVHAQFGMDMFPGSMISGSMATCQDGHVPTLTCENPVPESCACTCSDGLTFNQSRPPVVDPVPPPVEPPVEPPHQLDEKPCTTEIIQSWARLELHHKIGSYEPSEMKTKDISFPEDTVLVVADAARRCQHFEVSIDGKVIGQTYGKGPLDYFDCGTVDNCINNHEGSVGYFTLPKDYIVDNWLMRVVGNHVLGMRWVGITEPCKDIEKALGYFQIYKPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZX5</accession>
    <name>W6YZX5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_96956</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688611.1">
        <property type="nucleotide sequence ID" value="XM_007690421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZX5"/>
    <dbReference type="STRING" id="930090.W6YZX5"/>
    <dbReference type="GeneID" id="19128956"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96956"/>
    <dbReference type="eggNOG" id="KOG2431">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003818_0_0_1"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000037">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF49">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886291" description="alpha-1,2-Mannosidase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="493"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="582"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="385"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="593" mass="66829" checksum="F434BDCE28A86BCE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0F8</accession>
    <name>W6Z0F8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_28098</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="KI964029">
        <property type="protein sequence ID" value="EUC43440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690044.1">
        <property type="nucleotide sequence ID" value="XM_007691854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0F8"/>
    <dbReference type="STRING" id="930090.W6Z0F8"/>
    <dbReference type="GeneID" id="19121241"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28098"/>
    <dbReference type="eggNOG" id="ENOG502SJT6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020817_0_1_1"/>
    <dbReference type="OrthoDB" id="412382at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF1">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE CELB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889578" description="Glucanase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC43440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="418" mass="44944" checksum="0550564B6466D65B" modified="2014-04-16" version="1">MARYALLAAALLGFTVAQTPGTTPEVHPKLTTWKCTKRGGCKAQNTAIVTDSAAHPIHQKNNSTLGCGSWGNGPDPTACPTKEACAKNCIIEGISDYSTVGVFTKGADLRLDMYSPAGNFVSPRVYLLSKDEKNYEMLQLTGNELTFDVDMSKLPCGMNGALYLSEMRADGGRSKLNPKGAAYGTGYCDAQCFVTPWINGEGNVAKQGVCCNEMDIWEANSRSTSIAPHTCGKPSIFGCTGDECSKTGLCDKNGCVDNPYKTRGDKAYYGLGLKVDTNRPFTVVTQFPAKNGVLQSIVRKYIQDGVVMDNAVKNITMDQAYCSAQGGAEMYNQLGGHKVMGDAMSRGMVLAMSVWWDEGGAMQWLDSGASGPCNATEGFPAEIIKKVKNPTVTFSKIKWGEIGSTFSTKKATEKRWEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0I6</accession>
    <name>W6Z0I6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_100751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964028">
        <property type="protein sequence ID" value="EUC43475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690028.1">
        <property type="nucleotide sequence ID" value="XM_007691838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0I6"/>
    <dbReference type="GeneID" id="19117739"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100751"/>
    <dbReference type="eggNOG" id="ENOG502SRT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033570_1_0_1"/>
    <dbReference type="OrthoDB" id="4657524at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018620">
        <property type="entry name" value="Ubiquitin3-bd_protein_But2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39613">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39613:SF1">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09792">
        <property type="entry name" value="But2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886471" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin 3 binding protein But2 C-terminal" evidence="2">
        <location>
            <begin position="57"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="223" mass="24794" checksum="82B441723D253AF4" modified="2014-04-16" version="1">MRIIAILLAFAATALAIPFENSTVELTPRAFITNPKECPTSFVQPHGDLPKGASFAPRDVFVISRLRPTEFFMPDSWATTTARDKCTVFNIPIDVDRARGKTCNLVFDFPNFKQAPGISRMVGRGRFKFHPFAHRGPVPRPTFTTWRNKPPLSSTPPISIKQFSPGNSYVLSSAPCWIPREQKGIVVRSGMLCSDDTMLAFKQSDDRCPMGLFLIISEPDGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0K2</accession>
    <name>W6Z0K2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ngg1p interacting factor 3 nif3 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_100694</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964027">
        <property type="protein sequence ID" value="EUC43490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689985.1">
        <property type="nucleotide sequence ID" value="XM_007691795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0K2"/>
    <dbReference type="GeneID" id="19117725"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100694"/>
    <dbReference type="eggNOG" id="ENOG502SKBF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070095_0_0_1"/>
    <dbReference type="OrthoDB" id="2592744at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.30">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799:SF14">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1 TYPE 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="NGG1 INTERACTING FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="DUF34_NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602678-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="33111" checksum="0797E0663E9208C4" modified="2014-04-16" version="1">MSRPKKITHAAVTRFVETLLPLKENDVQRLYHVPRNPRYDAETAIVEQIILSVTPTPGVYSLIGYPLDDNTAGSTAQIYPRPPRTLCFLHRPFNLNRRSVRKGTLVLSSHTSFDEVLTVGWNTALAQRLGIDTANCLCVQGYKGDLERRIGVIGQITMPLQELLIQIQEQFGVSELAHVGLSDEIRFVAIMNAFNEGEVHRVFQMTQERGWIAPDEDGRHLLYLTGQPRVSGLEAAKALGMSVACVGHRQAEDWGVRYMGETLRKAFPSAHVREIYEEEIPVVKEKEPAVQNLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0R5</accession>
    <name>W6Z0R5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Outer spore wall protein RRT8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_40520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964111">
        <property type="protein sequence ID" value="EUC41264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692206.1">
        <property type="nucleotide sequence ID" value="XM_007694016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0R5"/>
    <dbReference type="GeneID" id="19123888"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40520"/>
    <dbReference type="eggNOG" id="ENOG502QVX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062645_0_0_1"/>
    <dbReference type="OrthoDB" id="10012223at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005619">
        <property type="term" value="C:ascospore wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005628">
        <property type="term" value="C:prospore membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32877" checksum="00668CC02772613C" modified="2014-04-16" version="1">MSESRLRVPDKVKEVAKEDFDQYKQLASDAVRSAAYLYPFKGIAYFFTHRALWKPLAAKLLPTVSLGLGVTVMMFAVTYVPQAALLTLFNGPLAIVTTVLLVLSESSTIFSVLSKNFLIDDALIDTFDGTMVCRNQTALVSNERQVKSGSDPIGKLGKLVSKPFAKFTPKAIIRYFMYLPLNFIPIVGTFIFVILQGRKFGPTAHARYFQLKQMKKQEKERFIEERKAAYTSFGVPAVLLELVPVVGIFFCFTNTVGAALWAADMEQGVHPSGSSQGSTTAPKLRQQAEIAREREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1A3</accession>
    <name>W6Z1A3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_6886</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964021">
        <property type="protein sequence ID" value="EUC43720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689754.1">
        <property type="nucleotide sequence ID" value="XM_007691564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1A3"/>
    <dbReference type="GeneID" id="19125114"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6886"/>
    <dbReference type="eggNOG" id="ENOG502QQUM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001932_0_0_1"/>
    <dbReference type="OrthoDB" id="6019893at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032483">
        <property type="term" value="P:regulation of Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00029">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.200">
        <property type="match status" value="1"/>
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        <source>
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    <sequence length="1111" mass="123340" checksum="40293E780DAB8E7B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z394</accession>
    <name>W6Z394_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM5</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_93470</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
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            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
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        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
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        <property type="term" value="P:double-strand break repair via break-induced replication"/>
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        <property type="term" value="P:regulation of DNA-templated DNA replication initiation"/>
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        <property type="term" value="P:subtelomeric heterochromatin formation"/>
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        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
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        <property type="entry name" value="MCM5"/>
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        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
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    <dbReference type="InterPro" id="IPR001208">
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    </dbReference>
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        <property type="entry name" value="MCM_lid"/>
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        <property type="entry name" value="MCM_N"/>
    </dbReference>
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        <property type="entry name" value="MCM_OB"/>
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    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
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        <property type="match status" value="1"/>
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        <property type="entry name" value="MCM_lid"/>
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        <property type="entry name" value="MCM_OB"/>
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        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
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        <property type="entry name" value="MCMPROTEIN5"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MCM_2"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="323"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC46197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="724" mass="80600" checksum="9B31AD24D89AB29F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3B7</accession>
    <name>W6Z3B7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_93333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687226.1">
        <property type="nucleotide sequence ID" value="XM_007689036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3B7"/>
    <dbReference type="STRING" id="930090.W6Z3B7"/>
    <dbReference type="GeneID" id="19128252"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93333"/>
    <dbReference type="eggNOG" id="ENOG502SHBV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042166_0_0_1"/>
    <dbReference type="OrthoDB" id="6361347at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037473">
        <property type="entry name" value="Lcp-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539:SF1">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic" evidence="2">
        <location>
            <begin position="137"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="473" mass="53670" checksum="5F0EF25DCEA8515B" modified="2014-04-16" version="1">MAGRKYSKATEEDIRAVGNYSFHWTKEHVPKEKTDPLRFKHDELGAATVNIIQKIHQREQEAHKQRGEQIPKLDMFATLEANRHHDETLAEFLKQVNTVPDWVNWEQLERGQHFFYRYALGNIIGFALQGFVGENSASTSVVEVLLRTGGFSTRSLRRRLLETFQLVLEVTHSLDFIKPGGKGHETTIRVRLLHSMVQQRMLRVAEVKGPSYYDSSIHGPPMNTLDSIHALATFSCNHAWQQLPHMGLRPLQQEVDDYIALWRYVGHVIGTPTDFFTTTSQAKAIMESLSYNELHITPSSLIVGHNFVEALKDLPPVNISAGFIEAGSRRLNGDDICDQLGMGRPGWYPYACFKGHCWLVVALATAQRWIPSFEAWSIQFCREVLHNAIIHSKYGLKGGSLLDFKYVPNGQITGCEKNDRLDGDRMWFYERPLELLYFIVFCAGCLSMIGSAIIAAWLLRGVVPYNVALLGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3L0</accession>
    <name>W6Z3L0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_98410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxB family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964006">
        <property type="protein sequence ID" value="EUC44323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689142.1">
        <property type="nucleotide sequence ID" value="XM_007690952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3L0"/>
    <dbReference type="GeneID" id="19129260"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98410"/>
    <dbReference type="eggNOG" id="ENOG502SNJ3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087059_2_0_1"/>
    <dbReference type="OrthoDB" id="5294024at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039020">
        <property type="entry name" value="PaxB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42038">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42038:SF4">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25129">
        <property type="entry name" value="Pyr4-TMTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="249" mass="29114" checksum="7F18CE0780D37ADA" modified="2014-04-16" version="1">MPFEAAQKLSSYHLIPQSVDVSLAPPESYFYITDFLIISCGILYTLCYAFYTMRTYSDRFLAGTVQFLSATMAYEIYYAYVCTTTTLQRACFFVWFLFDITFVSVALKYAYGPGERGRTIVKLLWQTPAWMGFLWWVGGLWPDERGQKTAFFTGLYLELPIGWGQILYLVKRGDTKGQSLEIWITRYLGCIAAFLVFIWRYINVPENWAYVGNWWSIGGMIVTLLPETVYPFFYVWAHRKEREKKEKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4N2</accession>
    <name>W6Z4N2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_92131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686786.1">
        <property type="nucleotide sequence ID" value="XM_007688596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4N2"/>
    <dbReference type="STRING" id="930090.W6Z4N2"/>
    <dbReference type="GeneID" id="19128019"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92131"/>
    <dbReference type="eggNOG" id="ENOG502SPQT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098340_0_0_1"/>
    <dbReference type="OrthoDB" id="3907216at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.70">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="26776" checksum="2FB6B7AA4AE7FF37" modified="2014-04-16" version="1">MATQTLHGSCACGRNRYVIEIPAQQVRQAELRYDNTPASRYHAANPLTLWLRVPLPWYTSATFAQFPDETRLSIKRNFESPFASHTRRQFCGYCGTQLSSWNERTRDEAEHISLTVGSLLDEDQELLGDLGFIPSSDSSDDEGMPSAAPSRPTSSRTVVRSGPQSRGAPWFEEIVRNTRLGRFKQQRGAHTDSGVHVEWEVTEWTEGDGLDLDDEGSATPNKRKIGDIDDAEDAEMRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4P9</accession>
    <name>W6Z4P9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_6036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963999">
        <property type="protein sequence ID" value="EUC44703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688772.1">
        <property type="nucleotide sequence ID" value="XM_007690582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4P9"/>
    <dbReference type="STRING" id="930090.W6Z4P9"/>
    <dbReference type="GeneID" id="19124804"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6036"/>
    <dbReference type="eggNOG" id="KOG0841">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058290_0_0_1"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="5"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC44703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="274" mass="30477" checksum="02EC129BD4246092" modified="2014-04-16" version="1">MATERESKTFLARLCEQAERYDEMVTYMKEVAKVAGELTVDERNLLSVAYKNVVGTRRASWRIISSIEQKEESKGTEKHVGTIRDYRQKIETELEQVCQDVLNVLDDSLIPKAESGESKVFYHKMKGDYHRYLAEFASGEKRKVAATAAHEAYKTATDVAQTELTPTHPIRLGLALNFSVFYYEILNSPDRACHLAKQAFDDAIAELDSLSEESYRDSTLIMQLLRDNLTLWTSSDGNEGEGAAADAPKDEAKPAEDAAAATEAKPEETPAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4V3</accession>
    <name>W6Z4V3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_39318</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964054">
        <property type="protein sequence ID" value="EUC42634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690841.1">
        <property type="nucleotide sequence ID" value="XM_007692651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4V3"/>
    <dbReference type="GeneID" id="19123655"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39318"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002406_3_0_1"/>
    <dbReference type="OrthoDB" id="21416at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="780"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="813"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="883"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="890"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="907" mass="104054" checksum="B1A02D1A2200411C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5Y4</accession>
    <name>W6Z5Y4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_37056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963989">
        <property type="protein sequence ID" value="EUC45183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688294.1">
        <property type="nucleotide sequence ID" value="XM_007690104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5Y4"/>
    <dbReference type="STRING" id="930090.W6Z5Y4"/>
    <dbReference type="GeneID" id="19123174"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37056"/>
    <dbReference type="eggNOG" id="ENOG502S7P3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075340_0_0_1"/>
    <dbReference type="OrthoDB" id="5366687at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="204" mass="22727" checksum="15AD6CE6E0538804" modified="2014-04-16" version="1">MDSQMLHMLMATVELVNANLDTAPGSWRDQLPAIRNITTSFEISDTAPEQSPRCWQIPHVTVVQRVAFADADNGPIPDIADWCLRQLLTLLALYPRDAEILAFTVIGRHWLLRAQKALASIARAESELHSNEESSPYPLQSAKQPLVETQERINNADYVEARALLVPATDYLQSAVDAAREKGQLTGHLLLTASTLPFTQIFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z608</accession>
    <name>W6Z608_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DFDF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_5520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
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                <person name="Wang R."/>
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    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF12">
        <property type="entry name" value="BETA-XYLOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="7">
        <location>
            <begin position="329"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="544" mass="62054" checksum="89F48EE39230DF03" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z859</accession>
    <name>W6Z859_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964232">
        <property type="protein sequence ID" value="EUC39876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693606.1">
        <property type="nucleotide sequence ID" value="XM_007695416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z859"/>
    <dbReference type="GeneID" id="19119577"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110305"/>
    <dbReference type="HOGENOM" id="CLU_061412_0_0_1"/>
    <dbReference type="OrthoDB" id="3693656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="409" mass="45379" checksum="0BE297B38718F0C9" modified="2014-04-16" version="1">MAERIQQQQSGEQNREWVPSARSIQYYSRIANALFPPSYSTDDSDTPTWEDGLREIEAFNWLGSDEEDVHNKGEASPPEANLTPNPATVVEEYAPTDPAQELDHLSAQTTTTPVPPPGILEPTPVYEPANPVHRLESYLDTQSHSSTPIRPTTPPYQSPCEDPVETTQNAQPPRTLEYLQTFRYSPALETIREKKVPGDEVLVEMLYNTVVFDPSSTSSDPTQDDPNQLQEHFNNMKIREQGNPPPTTPPRPIPATIPFAPKKIQKYKVDLRSKAAIAGAAAAHRTTAPLPPIALFPKTLPKDKVNVRTKAIKAATEKATPEYRNKRVKTDNDDSRPKATASSSPTRKPRIRWTPLSTEDKPDSSPESPFMPAGVKPEYAPRLFASLRRYQKGPSADEGGDASKDANEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8M5</accession>
    <name>W6Z8M5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_93677</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963971">
        <property type="protein sequence ID" value="EUC46143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687372.1">
        <property type="nucleotide sequence ID" value="XM_007689182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8M5"/>
    <dbReference type="STRING" id="930090.W6Z8M5"/>
    <dbReference type="GeneID" id="19128306"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93677"/>
    <dbReference type="eggNOG" id="KOG0812">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044998_0_1_1"/>
    <dbReference type="OrthoDB" id="421009at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090083">
        <property type="term" value="P:regulation of inclusion body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd15844">
        <property type="entry name" value="SNARE_syntaxin5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021538">
        <property type="entry name" value="Syntaxin-5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF3">
        <property type="entry name" value="SYNTAXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11416">
        <property type="entry name" value="Syntaxin-5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="252"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="168"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC46143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="344" mass="38424" checksum="B9EE7FA82DCB2BEA" modified="2014-04-16" version="1">MAVSIQDRTEEFRSILAQAQRRQAQSKTGAQRQSLLTAQEKAQANASPRRQRSEFARNAAEVARGVASTMQKLERLSQLAKRKTLFDDRPVEFDELTFVIKQDMSALSGQVQALQQMNAKLHPKAKPGLDQEGEHNSNVVMLLKDKLQNVGTNFKDVLEVRTKNMQASRSRTEQFLSSAAQQSHSSLEPGRTDSPLYQTPQRGRSPGGFGRNTNAVQQDLLSLEPSGSSALTRGGAQSDAQLLLMEEAQPQNMYIQERGRAIESIESTIQELGGIFSQLAQMVSEQGEQIQRIDANTEDVVDNVEGAQRELMKYWSRVQGNRWLVAKMFGVLMIFFLLWVLISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8Q4</accession>
    <name>W6Z8Q4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_109712</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964201">
        <property type="protein sequence ID" value="EUC40071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693405.1">
        <property type="nucleotide sequence ID" value="XM_007695215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8Q4"/>
    <dbReference type="STRING" id="930090.W6Z8Q4"/>
    <dbReference type="GeneID" id="19119489"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109712"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037221_0_0_1"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF2">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="475"/>
            <end position="515"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="548" mass="62289" checksum="BF40EB8C6F3833DD" modified="2014-04-16" version="1"> </sequence>
</entry>
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        </recommendedName>
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            <taxon>Dothideomycetes</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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    <dbReference type="eggNOG" id="KOG3281">
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    </dbReference>
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    <dbReference type="OrthoDB" id="16535at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010591">
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    </dbReference>
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        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP11"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="138"/>
        </location>
    </feature>
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            <end position="81"/>
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    </feature>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC40511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="37682" checksum="97068DD9244E6103" modified="2014-04-16" version="1">MAMRFPPLRHALRQPLASPRATQRRWARVQDVRFLVTHDTQERVLAKYRDKLESKAREKGLRDLNELKEQYKDRIEELRKQAIVPGATGPLTPPPEHKQQQQRQTQNAPPPPSADGAQTSPPRAGAGSPTAPPPGVQTLNSFLAVDKIQDNTREEIEALWRMRHANNPQGIHFAVPASTFSNLLRSAKQHPSFVLPIPREMPADPDAAPDAQGETQQAVELHYLQFAHPHDHTTTLMFTTLAEFKLRGEFASPHTTVTFHQELADSHNLVLGQGLVVEKRGVSLDDARWLIMCMQKFYVQTDEGKGRSELLDMFTRGDSAFKVERLIDEAEKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA57</accession>
    <name>W6ZA57_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF803-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_25369</name>
    </gene>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="protein sequence ID" value="EUC46658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688631.1"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG2922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF85">
        <property type="entry name" value="DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G15880)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="300"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="368"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="46172" checksum="A1910B3873462BBB" modified="2014-04-16" version="1">MVEDKYIGLMLAMSSSLAIGASFVITKKGLNASIEKHGFDGDGFGYLQNPVWWAGIITMVLGEIFNFAAYAFAPAILVTPLGALSVLIGAVLGSYFLDEQLGRLGKIGCAICLIGSVIIVLHAPPDKEVQSVEEILDLALQPGFLFYCAFCVVFCVFMIYKIAPKYGRKNPLIYLSICSTSGSVSIMFIKAFGIALKMTFAGNNQFTHPSTYVFVILVVGCILTQMNYFNKALSQFSTNIVNPLYYVTFTTCTLVASCLLFQGFNTTSAVNTISLLCGFLIIFSGVYLLNLSREDPCADPALGSRFDGPPSDAISGFPTRRSMQSRRSGDPYEHQSNGVIRNSRSSYADVGDRSALMHDYDAENQFELGDLAGDSDDDLESGRNTKRPSFDEETRLSGRLSGTGRGRVQKESVQPKRNHSARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAC9</accession>
    <name>W6ZAC9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aspartyl aminopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_4161</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686678.1">
        <property type="nucleotide sequence ID" value="XM_007688488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAC9"/>
    <dbReference type="STRING" id="930090.W6ZAC9"/>
    <dbReference type="GeneID" id="19124097"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4161"/>
    <dbReference type="eggNOG" id="KOG2596">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019532_3_0_1"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002759">
        <property type="entry name" value="PRK02813.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF4">
        <property type="entry name" value="VACUOLAR AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="83"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC46738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="66186" checksum="A7067B64898DA833" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAP6</accession>
    <name>W6ZAP6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="24">DSC E3 ubiquitin ligase complex subunit A</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="25">Defective for SREBP cleavage protein A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="26">RING-type E3 ubiquitin transferase dscA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="32" type="ORF">COCMIDRAFT_86069</name>
    </gene>
    <organism evidence="32 33">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="32 33" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="32 33">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="22">Catalytic component of the DSC E3 ubiquitin ligase complex which is required for the srbA transcriptional activator proteolytic cleavage to release the soluble transcription factor from the membrane in low oxygen or sterol conditions. Required for growth during hypoxia and triazole drug susceptibility, as well as for virulence in a murine model of invasive pulmonary aspergillosis (IPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="23">Component of the DSC E3 ubiquitin ligase complex composed of dscA, dscB, dscC and dscD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Mitochondrion outer membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684644.1">
        <property type="nucleotide sequence ID" value="XM_007686454.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZAP6"/>
    <dbReference type="GeneID" id="19126793"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86069"/>
    <dbReference type="eggNOG" id="KOG0448">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0828">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002868_0_0_1"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008053">
        <property type="term" value="P:mitochondrial fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051646">
        <property type="term" value="P:mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000638">
        <property type="entry name" value="Transmembrane GTPase Fzo1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000626">
        <property type="entry name" value="Transmembrane ubiquitin ligase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021319">
        <property type="entry name" value="DUF2921"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027094">
        <property type="entry name" value="Mitofusin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465:SF0">
        <property type="entry name" value="SARCALUMENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465">
        <property type="entry name" value="TRANSMEMBRANE GTPASE FZO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11145">
        <property type="entry name" value="DUF2921"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <sequence length="1714" mass="191571" checksum="FD39C7F0DFC63892" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
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                <person name="Schackwitz W."/>
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                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="185" mass="20249" checksum="8554CEAAE9CF8E95" modified="2014-04-16" version="1">MADHHDGASPRELVLEACRRNNTELLEETLADLNAAAKKSDKKPADYVADILNNARDGLGNGCLHIAATYGSFEVIDMLLDQEGLEIDEIDRMEQDTPLHKAVRYVNSLEKDVWPHGQSIVAMLLDAGCDPRIRNKAKLKPVELVDPRNTELKSMLQKGEFAIQAGGDIVEDDDDGHAGSGSESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBH8</accession>
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    <protein>
        <submittedName>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_97215"/>
    <dbReference type="HOGENOM" id="CLU_2009317_0_0_1"/>
    <dbReference type="OrthoDB" id="3784937at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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            <end position="135"/>
        </location>
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        <location>
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            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
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        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="135" mass="14415" checksum="B2E317F13A1991A8" modified="2014-04-16" version="1">MSSLTIQESSNTQPQNPVNPGDDTSGTFKGDPSVPFKTGRSTDPAGLSTSVDKSSYGQQNASDTSEQRRGEDLKQNTKQEYEGSSNVGVKTGSESLLDSVERSVKESGQEDRSRVDVGQVTGGRKSRQNLVSVND</sequence>
</entry>
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        </recommendedName>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        </location>
    </feature>
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            <begin position="122"/>
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    </feature>
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        <location>
            <begin position="1"/>
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            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
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        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="46975" checksum="3F2271A626C2FB79" modified="2014-04-16" version="1">MASGKHEVNPIDKGRRTRSASTPRSTSTPRRGSTVGIQKRSFRRSTTRQASTAGTETSEPTEARKREGAKSFRFLDLPGEIRNRIYEYMCVEETQLVLVHRPRIASLRPRTRLDRSRTLPSDITAQEYDERLSSDSSITNGPETEIIPRETSRPFWGLTQASRQLRWEFRPLYFINQEIGVDLTNIPGYVNAFYASATRELATIGPSGERDSTLSFVGNITVAVRDTAIKEERGPRGIEVLPLLEILMNGFSLQVGFGRFVTSRYSTGGYQWQSDVEIKDLYRLLGHQIRRDYSYTETNERWEEILRCRSLASVRVHRVPMTIYVAAPGWVIPPKLLAISIPILPANGVYPPNVQIFRVPVVSRPYIHLIFRREKAEAWMTDFESVIPNNWLAQHGFDNMEHFEVKVGVEE</sequence>
</entry>
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    <accession>W6ZBS4</accession>
    <name>W6ZBS4_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963952">
        <property type="protein sequence ID" value="EUC47435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686011.1">
        <property type="nucleotide sequence ID" value="XM_007687821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBS4"/>
    <dbReference type="GeneID" id="19127586"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89958"/>
    <dbReference type="HOGENOM" id="CLU_2819372_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="67" mass="7377" checksum="BCB559A25415B1CA" modified="2014-04-16" version="1" fragment="single">EDTAGERVSTSISTVDILIQKTRENPVFMVLLVNCMQSLSCLSNSISPILSLTRRLHIKPPINPQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBT7</accession>
    <name>W6ZBT7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_33310</name>
    </gene>
    <organism evidence="11 12">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684179.1">
        <property type="nucleotide sequence ID" value="XM_007685989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBT7"/>
    <dbReference type="GeneID" id="19122288"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33310"/>
    <dbReference type="eggNOG" id="KOG1812">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015887_2_1_1"/>
    <dbReference type="OrthoDB" id="9977870at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="259"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="574"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="33"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="578"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="590"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="665" mass="76255" checksum="7B9F14C19DC7B734" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBV3</accession>
    <name>W6ZBV3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_1933</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684157.1">
        <property type="nucleotide sequence ID" value="XM_007685967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBV3"/>
    <dbReference type="STRING" id="930090.W6ZBV3"/>
    <dbReference type="GeneID" id="19119970"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1933"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_172_3_1"/>
    <dbReference type="OrthoDB" id="541276at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13993">
        <property type="entry name" value="STKc_Pat1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000549">
        <property type="entry name" value="Protein serine/threonine kinase (Ran1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="29"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="372"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC49272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="435" mass="47568" checksum="7CD59FE1095493AA" modified="2014-04-16" version="1">MYPTPPASPSQNGFCAPEDRLGQVLAGRLQLTGVLGVGAYGVVYTAVDIQTNIPYAVKALNKVGLEPRQRKFQQREIQLHHQASAHPNVVSLVKIMDAPDCTYVVIEYCPEGDLFSNITEQGKYVGNDAMAKRAFLQVLDAVEYCHSIGIYHRDLKPENVLVTDQGMTCKLADFGLATTDPVTSDFGCGSTFYMSPECQTSSPKPYSCYASAPNDVWSLGVMLVNLTCGRNPWKRASFDDSTFRAFMKDPKFLKTILPVSDELDAVLRRMFEFNPAKRATIPEIRDMIMRCSSFTATKSAVSSPMPTPSFGPVDYAQDPAYNQYYQTPAVPQFAPLPGSAYAPSPFQSSTSSGSSNSDGESVFSACSSASSASSNSSYHVSQSQPPKFSSRVPQPQQYVSPQPPANTWFQPFIQAANLVKHVSFQPSIMAPVHVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBW9</accession>
    <name>W6ZBW9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Translin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_90430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686180.1">
        <property type="nucleotide sequence ID" value="XM_007687990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBW9"/>
    <dbReference type="STRING" id="930090.W6ZBW9"/>
    <dbReference type="GeneID" id="19127682"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90430"/>
    <dbReference type="eggNOG" id="KOG3067">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079179_0_0_1"/>
    <dbReference type="OrthoDB" id="829at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990605">
        <property type="term" value="F:GU repeat RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035939">
        <property type="term" value="F:microsatellite binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14819">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.200:FF:000002">
        <property type="entry name" value="Putative translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033956">
        <property type="entry name" value="Translin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27702" checksum="E9F64A6465CE9FE5" modified="2014-04-16" version="1">MASQSGMVNPAVFQDLQARIDEDSAVRDELRDIIQALEKHNRNVSFVLSRAHSTPVSELSEILKAAQEPIDNVIETVSKLSQAASKMPYYKFNNMWSRQMQGACESILFWGWLGGYKYEGGAVQCGRLLTIEELGEIFKIPVNLKERDEFHLSLEEYLHSLMTLVEELTRLARNAVTLGDYERPLLINQFVKDLHAGFQILNLKNDSLRRRSDGLKYRVKDVEDVVYDLSLRNLVPKKGEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC29</accession>
    <name>W6ZC29_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acyl-coenzyme A diphosphatase SCS3</fullName>
            <ecNumber evidence="10">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">FIT family protein SCS3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SCS3</name>
        <name evidence="10" type="synonym">FIT2B</name>
        <name evidence="15" type="ORF">COCMIDRAFT_84676</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65568"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57368"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:156554"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-octadecenoyl-CoA + H2O = S-(9Z-octadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:156553"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:50044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:132023"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>hexadecanoyl-CoA + H2O = S-hexadecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:50032"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:132018"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Endoplasmic reticulum membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="10"/>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684106.1">
        <property type="nucleotide sequence ID" value="XM_007685916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC29"/>
    <dbReference type="STRING" id="930090.W6ZC29"/>
    <dbReference type="GeneID" id="19126505"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84676"/>
    <dbReference type="eggNOG" id="KOG3750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009640_2_0_1"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14791">
        <property type="entry name" value="GH36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000118">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.60">
        <property type="entry name" value="alpha-galactosidase from lactobacil brevis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03231">
        <property type="entry name" value="SCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038417">
        <property type="entry name" value="Alpga-gal_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019388">
        <property type="entry name" value="FIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002252">
        <property type="entry name" value="Glyco_hydro_36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031705">
        <property type="entry name" value="Glyco_hydro_36_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031704">
        <property type="entry name" value="Glyco_hydro_36_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046400">
        <property type="entry name" value="SCS3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10261">
        <property type="entry name" value="FIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16874">
        <property type="entry name" value="Glyco_hydro_36C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16875">
        <property type="entry name" value="Glyco_hydro_36N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02065">
        <property type="entry name" value="Melibiase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00743">
        <property type="entry name" value="GLHYDRLASE36"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 36 N-terminal" evidence="14">
        <location>
            <begin position="355"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 36 C-terminal" evidence="13">
        <location>
            <begin position="965"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC49357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1045" mass="115292" checksum="2455D61452AA19EA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCD5</accession>
    <name>W6ZCD5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein SDA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_84380</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for 60S pre-ribosomal subunits export to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SDA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684004.1">
        <property type="nucleotide sequence ID" value="XM_007685814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCD5"/>
    <dbReference type="STRING" id="930090.W6ZCD5"/>
    <dbReference type="GeneID" id="19126456"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84380"/>
    <dbReference type="eggNOG" id="KOG2229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009161_2_1_1"/>
    <dbReference type="OrthoDB" id="2196187at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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        <property type="entry name" value="Sda1"/>
    </dbReference>
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        <property type="entry name" value="SDA1_C"/>
    </dbReference>
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        <property type="entry name" value="SDA1_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012977">
        <property type="entry name" value="SDA1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730">
        <property type="entry name" value="HSDA/SDA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730:SF0">
        <property type="entry name" value="PROTEIN SDA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21638">
        <property type="entry name" value="SDA1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05285">
        <property type="entry name" value="SDA1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08158">
        <property type="entry name" value="SDA1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SDA1 N-terminal" evidence="9">
        <location>
            <begin position="67"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 middle" evidence="8">
        <location>
            <begin position="547"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 C-terminal" evidence="10">
        <location>
            <begin position="702"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="257"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="534"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="679"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="591"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="742"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC49467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="755" mass="84093" checksum="5EF6AF1675197C73" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCD8</accession>
    <name>W6ZCD8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Solute carrier family 40 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_106273</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in iron transport and iron homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI964105">
        <property type="protein sequence ID" value="EUC41396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCD8"/>
    <dbReference type="STRING" id="930090.W6ZCD8"/>
    <dbReference type="GeneID" id="19118830"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106273"/>
    <dbReference type="eggNOG" id="KOG2601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020370_5_0_1"/>
    <dbReference type="OrthoDB" id="648861at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17480">
        <property type="entry name" value="MFS_SLC40A1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="251"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC41396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="537" mass="58812" checksum="D0574FA867060019" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCM5</accession>
    <name>W6ZCM5_COCMI</name>
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        <recommendedName>
            <fullName evidence="11">ENTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_34773</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLA2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685755.1">
        <property type="nucleotide sequence ID" value="XM_007687565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCM5"/>
    <dbReference type="STRING" id="930090.W6ZCM5"/>
    <dbReference type="GeneID" id="19122637"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34773"/>
    <dbReference type="eggNOG" id="KOG0980">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004601_0_0_1"/>
    <dbReference type="OrthoDB" id="10262320at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043325">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080025">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17007">
        <property type="entry name" value="ANTH_N_Sla2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1410.10:FF:000004">
        <property type="entry name" value="Cytoskeleton assembly control protein Sla2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000021">
        <property type="entry name" value="Cytoskeleton assembly control protein Sla2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="14"/>
            <end position="144"/>
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        </location>
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            <begin position="311"/>
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    </evidence>
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    </evidence>
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        <source>
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            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
    <sequence length="1056" mass="120102" checksum="91E42B2E9BE65AD7" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6ZCR3</accession>
    <name>W6ZCR3_COCMI</name>
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    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_29699</name>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="103"/>
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        </location>
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        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="364" mass="41302" checksum="C8D1AA47F278B208" modified="2014-04-16" version="1">MVSEQRSTDALRATEDARPTTADRIDTTPVPTVQIDGVSDDKEQASDMTAANNTTSLNPSAQPSRAPSPNRHALFPHTQVTYDDPDFTRPPPLNYSLRTRKKAIFWFWTLIILDCVCMPIGLYFGMWYGLTRDQLSANAVFSISTALLGTVSIVEYFIRFHRLWKKNSSCRVIGAKRWYLDWFHWNLSVGWFFVMIELIAGTCPHDPPIRVLAMPAPTMMFAIGVELLLVDILRIMKVPAPCRISSLPQGAPLRPGIYAYIEDICAVDGSGGTEFRQRLNLRYQASKAFREMLHRLTLFWAIGAIVTSAVCTAIIFTIQRDAAYVVGWVVPFLWAGIWAAITIKWVQLELKREYEQWTTAQYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
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    <name>W6ZCT6_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">NADH-ubiquinone oxidoreductase 9.5 kDa subunit</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_84202</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502S74C">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <dbReference type="CDD" id="cd22903">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR38488">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38488:SF1">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9079" checksum="2A1325496106364F" modified="2014-04-16" version="1">MSGVPPSPLFFRQPLRYMKWAAYNKPAYFYSIVIGLAGPVMLVTVPPIRRYMGEEPIQKIPLTYPVPKGPRPRPAGFDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCU1</accession>
    <name>W6ZCU1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_105853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964097">
        <property type="protein sequence ID" value="EUC41556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691934.1">
        <property type="nucleotide sequence ID" value="XM_007693744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCU1"/>
    <dbReference type="GeneID" id="19118760"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105853"/>
    <dbReference type="HOGENOM" id="CLU_3147104_0_0_1"/>
    <dbReference type="OrthoDB" id="3686375at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="49" mass="5287" checksum="3D0564FDE1651F7D" modified="2014-04-16" version="1" fragment="single">ATLDTGRIEAVANTAFDVSLMVMGTVALCQPRCTGYSSRHMEALVRPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD53</accession>
    <name>W6ZD53_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_24442</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685746.1">
        <property type="nucleotide sequence ID" value="XM_007687556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD53"/>
    <dbReference type="GeneID" id="19120591"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24442"/>
    <dbReference type="eggNOG" id="KOG0757">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_6_0_1"/>
    <dbReference type="OrthoDB" id="269120at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015218">
        <property type="term" value="F:pyrimidine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990519">
        <property type="term" value="P:pyrimidine nucleotide import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049562">
        <property type="entry name" value="SLC25A33/36-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829:SF4">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="52"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="173"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="286"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC47738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="382" mass="41827" checksum="7EA95D2D463BD28A" modified="2014-04-16" version="1">MALQETSRPRGIRDSPAHPLQPLPPSSRELGEVTPPKRADGASVAKEDPKSGKSWAHFVAGGLGGMASATLTAPLDVLKTRLQSTFYQQHLAAMRAARGLPPIESMSFARSSLLHIRETGEILWQVPKAEGWRALFKGLGPNLVGVVPARAINFFAYGNGKRLISTHFNNGQEAAWVHLCSAAAAGIVTGTATNPIWLVKTRLQLDKNTHSDGRGRQYKNAFDCTMQTIRKEGVRGLYRGLTASYLGVTESTLQWMLYEQMKLSLARREERVLASGKPPTIWDQTVAWTGKLTAAGSAKFVAALITYPHEVVRTRLRQAPMADGRQKYTGLVQCFRLIWKEEGMAALYGGLVPHMFRVVPSAAIMFGTYEGVLKLLGESSNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDL4</accession>
    <name>W6ZDL4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_83243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683554.1">
        <property type="nucleotide sequence ID" value="XM_007685364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDL4"/>
    <dbReference type="GeneID" id="19126216"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83243"/>
    <dbReference type="HOGENOM" id="CLU_2978786_0_0_1"/>
    <dbReference type="OrthoDB" id="3686817at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="58" mass="6895" checksum="9050C256A6C1C346" modified="2014-04-16" version="1">MRREVAEYIAQRTRLRILRGAMRGLRRRQAADPRGREEDLEALDEQIRELALLLNYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEF1</accession>
    <name>W6ZEF1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SART-1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_2865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNU66/SART1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963943">
        <property type="protein sequence ID" value="EUC48248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685203.1">
        <property type="nucleotide sequence ID" value="XM_007687013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEF1"/>
    <dbReference type="STRING" id="930090.W6ZEF1"/>
    <dbReference type="GeneID" id="19121345"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2865"/>
    <dbReference type="eggNOG" id="KOG2217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009379_2_0_1"/>
    <dbReference type="OrthoDB" id="5583at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000481">
        <property type="term" value="P:maturation of 5S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005011">
        <property type="entry name" value="SNU66/SART1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152">
        <property type="entry name" value="SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152:SF5">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03343">
        <property type="entry name" value="SART-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="285"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="360"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="414"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="636"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="518"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="373"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="636"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="678" mass="75842" checksum="98B08D8EBD1908E2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEF6</accession>
    <name>W6ZEF6_COCMI</name>
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        <recommendedName>
            <fullName evidence="1">geranylgeranyl diphosphate synthase</fullName>
            <ecNumber evidence="1">2.5.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_104929</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.29" evidence="1"/>
    <dbReference type="EMBL" id="KI964081">
        <property type="protein sequence ID" value="EUC41906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691589.1">
        <property type="nucleotide sequence ID" value="XM_007693399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEF6"/>
    <dbReference type="STRING" id="930090.W6ZEF6"/>
    <dbReference type="GeneID" id="19118605"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104929"/>
    <dbReference type="eggNOG" id="KOG0777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_10_0_1"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046165">
        <property type="term" value="P:alcohol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF72">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G01210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC41906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="675" mass="75239" checksum="22D801CAA15C402C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEK9</accession>
    <name>W6ZEK9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_87634</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685169.1">
        <property type="nucleotide sequence ID" value="XM_007686979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEK9"/>
    <dbReference type="GeneID" id="19127105"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87634"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF4">
        <property type="entry name" value="CYTOCHROME P450 98A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC48308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="61017" checksum="D2BF8F82F46DBE95" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF36</accession>
    <name>W6ZF36_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spc7 kinetochore protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_25787</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963971">
        <property type="protein sequence ID" value="EUC46124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687335.1">
        <property type="nucleotide sequence ID" value="XM_007689145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF36"/>
    <dbReference type="STRING" id="930090.W6ZF36"/>
    <dbReference type="GeneID" id="19120822"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25787"/>
    <dbReference type="eggNOG" id="ENOG502QRS4">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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        </location>
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        </location>
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        </location>
    </feature>
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        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
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        </location>
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        </location>
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    </feature>
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            <begin position="723"/>
            <end position="735"/>
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    </feature>
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            <dbReference type="SMART" id="SM00787"/>
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            <dbReference type="EMBL" id="EUC46124.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="1253" mass="138104" checksum="9F3F640837482096" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
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            <position position="54"/>
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    </feature>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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    <accession>W6ZGG6</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_92525</name>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="10423647at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="57" mass="6577" checksum="58CBBBACAA708780" modified="2014-04-16" version="1" fragment="single">PHTSIWRVVKRPTERTTTRGNMYKDDGRGPNLHPGIEESGVVYFAAYIEMKGFFLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIU4</accession>
    <name>W6ZIU4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_1333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683489.1">
        <property type="nucleotide sequence ID" value="XM_007685299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIU4"/>
    <dbReference type="GeneID" id="19119843"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1333"/>
    <dbReference type="eggNOG" id="ENOG502SQUF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075891_1_0_1"/>
    <dbReference type="OrthoDB" id="2951834at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="2">
        <location>
            <begin position="96"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="285" mass="32061" checksum="A547ED3C571ACC4D" modified="2014-04-16" version="1">MAMAYYFAAHFNVSNNHMSDNAISTTTTFPLHTSPAGEQTHHPTTPSKRLPTASQKQSIFFLLPAELRNQIYDYLLCANTPNRNSLVAYSQQRSHAPQPIYPAILATCKRIHNEAQDLLYSTHVFQAHPSLLTSLPHLVSPWKPLLDASAIAKIRRWYLSVRLDTDPRFTEKQATAAFSGAEYLEIHAWQSMFDGCDDSVLRLFAGIRGVRVARVTGCAQAEFAAWLEGQMMRPVEEEEEMEVVDERCSCAKGVCGKCGERIVCEEKKAVPWIGQERGVWTFGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ98</accession>
    <name>W6ZJ98_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_44497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964022">
        <property type="protein sequence ID" value="EUC43661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689807.1">
        <property type="nucleotide sequence ID" value="XM_007691617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ98"/>
    <dbReference type="STRING" id="930090.W6ZJ98"/>
    <dbReference type="GeneID" id="19124240"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_44497"/>
    <dbReference type="eggNOG" id="ENOG502S8TM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002639_8_3_1"/>
    <dbReference type="OrthoDB" id="5362512at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF11">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="67"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="421" mass="48836" checksum="ED7E5153642A40D8" modified="2014-04-16" version="1" fragment="single">DHTSSTSSFELASMWLRDCVQSHPQCNSHKDGTLWYPTRLLHLVESGGKEGYVRLIRTAETSPNEHYATLSHRWGNTRPLQLTKSAASDPNHRFLVADMPKTFQEAIQVSKRLGIQYLWVDSLCIIQEGDNLRDWYQEAGLMDKVYMHSYLNIAAADAEDGTKGLFRQRPPLPLGRQRVAVNTKDIKPWPDCANYFLMTDFMLWSHSLDNSPLHNRGWVFQERFLAPRNLHFFRDQLFFECNERIVCETFPKELPNLSTHLTAVSLKTKLWTQADLSVLPDRYREDLRNFWYSEVVSLYSPMDLSVSTDKLIALSGIAKIFMARLEDTYVAGMWRSQLEDSLLWHVELQNLWPRPLVYRSPTWSWVSVDGRIRPNLYWTDRRLLIHVEDVVLSYAAEDTTGAITGGWVDLRGILKPVRLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKG1</accession>
    <name>W6ZKG1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_32096</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682853.1">
        <property type="nucleotide sequence ID" value="XM_007684663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKG1"/>
    <dbReference type="GeneID" id="19122026"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32096"/>
    <dbReference type="HOGENOM" id="CLU_161482_0_0_1"/>
    <dbReference type="OrthoDB" id="10314795at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="127" mass="13857" checksum="8DE62CF66BC396A5" modified="2014-04-16" version="1">MLRRGSLLATTPTREPCMFPRQAQARRLDLSIPSNIYTPCTISHLSPSRYRALRPAIDGLLTSNAHLNRWILRASWTPPHPPIFVIGSAGETGDLGCTPPCHTPAIPCIQHDAYSVSVHVRVGADPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKQ9</accession>
    <name>W6ZKQ9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_24141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963945">
        <property type="protein sequence ID" value="EUC48089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685402.1">
        <property type="nucleotide sequence ID" value="XM_007687212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKQ9"/>
    <dbReference type="GeneID" id="19120548"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24141"/>
    <dbReference type="HOGENOM" id="CLU_1326171_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="207" mass="23039" checksum="BA6526FA91FE377A" modified="2014-04-16" version="1">MSDFRMPAIATLLNGRLSFPPPSLLPPKTPSLRDFPFSRIFSGIISAICVRLEFLVTTACYFERVAPVEGSRRGLPFVDYNVYMMYAHTRIHTHTHTSYSAPLKKRHPSKKKGIRIPNNRILTCVSLQATCALILRRLRRRGNFSRDVPATGSGQASSSKVVVAHRTDKKKTPEHAGQTTTVPVNRQPAANNSQKQVREGKGNAKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKT9</accession>
    <name>W6ZKT9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">E3 ubiquitin-protein ligase listerin</fullName>
            <ecNumber evidence="5 16">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">RING-type E3 ubiquitin transferase listerin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_2921</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Mediates ubiquitination of proteins derived from mRNAs lacking stop codons (non-stop proteins) and other translation arrest products induced by poly-lysine sequences and tandem rare codons. Ubiquitination leads to CDC48 recruitment for extraction and degradation of the incomplete translation product. May indirectly play a role in chromatin function and transcription.</text>
    </comment>
    <comment type="function">
        <text evidence="16">E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the ribosome quality control complex (RQC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the LTN1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5 16"/>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685291.1">
        <property type="nucleotide sequence ID" value="XM_007687101.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZKT9"/>
    <dbReference type="GeneID" id="19121458"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2921"/>
    <dbReference type="eggNOG" id="KOG0803">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000471_0_0_1"/>
    <dbReference type="OrthoDB" id="6108at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16491">
        <property type="entry name" value="RING-CH-C4HC3_LTN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000038">
        <property type="entry name" value="E3 ubiquitin-protein ligase listerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039795">
        <property type="entry name" value="LTN1/Rkr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054477">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054476">
        <property type="entry name" value="Ltn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054478">
        <property type="entry name" value="LTN1_UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039804">
        <property type="entry name" value="RING-CH-C4HC3_LTN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE LISTERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389">
        <property type="entry name" value="ZINC FINGER PROTEIN 294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22958">
        <property type="entry name" value="Ltn1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22999">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23009">
        <property type="entry name" value="UBC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01197">
        <property type="entry name" value="FANCL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13 16" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="1566"/>
            <end position="1612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC48129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1618" mass="179255" checksum="F94C15BE430E07F2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLB1</accession>
    <name>W6ZLB1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_68439</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="KI964005">
        <property type="protein sequence ID" value="EUC44381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689093.1">
        <property type="nucleotide sequence ID" value="XM_007690903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLB1"/>
    <dbReference type="STRING" id="930090.W6ZLB1"/>
    <dbReference type="GeneID" id="19125099"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_68439"/>
    <dbReference type="eggNOG" id="KOG2571">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022329_0_0_1"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF41">
        <property type="entry name" value="CHITIN SYNTHASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="525" mass="59883" checksum="FBE2ED092CA94A51" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLE0</accession>
    <name>W6ZLE0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_31788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682544.1">
        <property type="nucleotide sequence ID" value="XM_007684354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLE0"/>
    <dbReference type="GeneID" id="19121965"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31788"/>
    <dbReference type="eggNOG" id="ENOG502STUS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090405_0_0_1"/>
    <dbReference type="OrthoDB" id="3791134at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="217" mass="21308" checksum="51E152C8F7F24F5C" modified="2014-04-16" version="1">MVSQPIGTKKTPVTSTAKKTPVKSSAKKVPVKAPAVQPPKKPINTALQKKPVTTTPKKPVPTTALKKTGTAVGQKKPLPAPAKKPIPQPQQQGWLSKGLSAAQSGIGSAVGAATTGISNAAGAVVTAAGSGVAGAGRGAGASITNTSRTWGDMVREYGNSLKDMTGATGSRSTTHKNPLGLSTSAAGGMASMASRPGVPGLSGGSARTGTASNPLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLL6</accession>
    <name>W6ZLL6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_6179</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688967.1">
        <property type="nucleotide sequence ID" value="XM_007690777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLL6"/>
    <dbReference type="STRING" id="930090.W6ZLL6"/>
    <dbReference type="GeneID" id="19124872"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6179"/>
    <dbReference type="eggNOG" id="KOG2189">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005230_0_0_1"/>
    <dbReference type="OrthoDB" id="10264220at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026028">
        <property type="entry name" value="V-type_ATPase_116kDa_su_euka"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001293">
        <property type="entry name" value="ATP6V0A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="544"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="574"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="639"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="781"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="686"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC44476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="854" mass="97472" checksum="FCBE4D5DB14151E0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMI7</accession>
    <name>W6ZMI7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">adenosylmethionine decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_97319</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic AdoMetDC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.50" evidence="4"/>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688694.1">
        <property type="nucleotide sequence ID" value="XM_007690504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMI7"/>
    <dbReference type="STRING" id="930090.W6ZMI7"/>
    <dbReference type="GeneID" id="19129032"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97319"/>
    <dbReference type="eggNOG" id="KOG0788">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023050_0_1_1"/>
    <dbReference type="OrthoDB" id="1068353at2759"/>
    <dbReference type="UniPathway" id="UPA00331">
        <property type="reaction ID" value="UER00451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006597">
        <property type="term" value="P:spermine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.90.10:FF:000008">
        <property type="entry name" value="S-adenosylmethionine decarboxylase proenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.90.10:FF:000023">
        <property type="entry name" value="S-adenosylmethionine decarboxylase proenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048283">
        <property type="entry name" value="AdoMetDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001985">
        <property type="entry name" value="S-AdoMet_decarboxylase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018166">
        <property type="entry name" value="S-AdoMet_deCO2ase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00535">
        <property type="entry name" value="SAM_DCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570">
        <property type="entry name" value="S-ADENOSYLMETHIONINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570:SF0">
        <property type="entry name" value="S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01536">
        <property type="entry name" value="SAM_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01336">
        <property type="entry name" value="ADOMETDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="12" id="KW-0704">Schiff base</keyword>
    <keyword evidence="8" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC44796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="532" mass="58997" checksum="D3D71E12C6338AA9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMN3</accession>
    <name>W6ZMN3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_97131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963996">
        <property type="protein sequence ID" value="EUC44851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688652.1">
        <property type="nucleotide sequence ID" value="XM_007690462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMN3"/>
    <dbReference type="GeneID" id="19128993"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97131"/>
    <dbReference type="HOGENOM" id="CLU_3001892_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="57" mass="6145" checksum="6217E9111C11DEF3" modified="2014-04-16" version="1" fragment="single">SPSRIPSNPPPPTPLPPIPIPIPTPIPPSTNPPHPSLDNLVNPIRQIRLPLPPFLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMT9</accession>
    <name>W6ZMT9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle subunit SRP14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Signal recognition particle 14 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_79500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SRP14 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682217.1">
        <property type="nucleotide sequence ID" value="XM_007684027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMT9"/>
    <dbReference type="STRING" id="930090.W6ZMT9"/>
    <dbReference type="GeneID" id="19125487"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79500"/>
    <dbReference type="eggNOG" id="ENOG502SCBK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094309_1_0_1"/>
    <dbReference type="OrthoDB" id="19209at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003210">
        <property type="entry name" value="Signal_recog_particle_SRP14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12013">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02290">
        <property type="entry name" value="SRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC51308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="140" mass="15717" checksum="D1D063D07C1DAF14" modified="2014-04-16" version="1">MGREHLSNDEFFAKLANLFEYTQTKGHGSVYLVQKRMTLGTTATPPPANKVADDPLWDTHPEDSLPVLIRAHNNKSDKKAGTDRKKVDKIELSTVVKPEDLDGFYARYAEACKAGMSGLKKRDKKKAKKTKKKKKVETKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN17</accession>
    <name>W6ZN17_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">37S ribosomal protein S25, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_26830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Component of the mitochondrial small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS23 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688529.1">
        <property type="nucleotide sequence ID" value="XM_007690339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN17"/>
    <dbReference type="STRING" id="930090.W6ZN17"/>
    <dbReference type="GeneID" id="19121011"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26830"/>
    <dbReference type="eggNOG" id="ENOG502RZQQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081350_0_0_1"/>
    <dbReference type="OrthoDB" id="5542239at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23701">
        <property type="entry name" value="At1g26750"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059242">
        <property type="entry name" value="mS23_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016939">
        <property type="entry name" value="Ribosomal_mS23_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37799">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37799:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13741">
        <property type="entry name" value="MRP-S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029764">
        <property type="entry name" value="RSM25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="229"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR029764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="255" mass="29231" checksum="75C6738E71169F51" modified="2014-04-16" version="1">MGRYDFRPLRVRQTAKALFDAKRNPELPQWYDVIGNIPPGETLARPVLRVPKMRKARKASKLFKPLPIAYPEDKLRSEFFGDHPWELARPRLVVEDSGNDSKNYDWSKIVQPGKQLDGESVVQRQMWLMKNASLSKASAYDVARREFYKHRHLSEIRSRIAKEEALHVGAYFGKGPLEIGMELEDRQWENWKAWATKQIEDEQAMRAQMFSGQQDDGVGTDMSSNEYDQAIEELQPVAPNNPQGQRPLGGVAAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNI6</accession>
    <name>W6ZNI6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_26632</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963990">
        <property type="protein sequence ID" value="EUC45131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688334.1">
        <property type="nucleotide sequence ID" value="XM_007690144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNI6"/>
    <dbReference type="STRING" id="930090.W6ZNI6"/>
    <dbReference type="GeneID" id="19120966"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26632"/>
    <dbReference type="eggNOG" id="ENOG502RTDE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060600_0_0_1"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF14">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="9">
        <location>
            <begin position="52"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA substrate" evidence="7">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC45131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="389" mass="44687" checksum="5E454F23E954D39E" modified="2014-04-16" version="1">MNRAISPPPAKRRKTTTTTKSTASTKSSQETTSSISSTILPPLEANTFRIFSWNINGISPFLQPSITSFFKAPKGSHNEDSKDEIYPTSLRAFLHRHHWPSILFLQEVKIASKDIKTQDAVRTAINSYLPPETSSNTSKGPLYDAHFTLPTDPHNARGPRGSGKVYGVCSILRRDLNNIYTTTVRTVDWDREGRISIVEITCRVTLSKLAIFHIYAVNGTEYLYHDTRSGAVQGTRHDRKREFHRLLMEECKRLERQGWDVLLAGDMNVAPDERDGHPKLRVFPRDHVVNRADFHDMLLEGRDEEKKSIGLNGIDIWRKMHEQERRYTYYPRTREWGTSCDRVDYFIAGRRLWEKGCVKACGIMNSEAERGPSDHVPIWADIEFKINRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRI8</accession>
    <name>W6ZRI8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_82490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963925">
        <property type="protein sequence ID" value="EUC50124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683296.1">
        <property type="nucleotide sequence ID" value="XM_007685106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRI8"/>
    <dbReference type="STRING" id="930090.W6ZRI8"/>
    <dbReference type="GeneID" id="19126065"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82490"/>
    <dbReference type="eggNOG" id="ENOG502SQGD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068709_2_0_1"/>
    <dbReference type="OrthoDB" id="5410926at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39599:SF1">
        <property type="entry name" value="GPI-ANCHORED PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39599">
        <property type="entry name" value="GPI-ANCHORED PROTEIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887261" evidence="1">
        <location>
            <begin position="18"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="263" mass="26192" checksum="419A0D2819BB7BAF" modified="2014-04-16" version="1">MRAAFAPLLLAPLAALAAPDLVADFEPAVEGLQNKVYDSMPTAPANVPAELLKRQGNACANNYFDCARLGAPGLCCPRTAVCSADQAGHVACCPQGAACTGALAAPTANPTATTSVPFVIASTTTGGPFVQQTNGANHGSTVQNQFYPFPYIPTTYQNAAACSSAYTSCQSDAASCTSALANGAPGVTVSAPNGGATITAIPSVGLSSAQSICSSLSSLGCSQLTVEACAAFDGSGNAAWRAPCRDYLMTAGVAIGIAGQLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZS30</accession>
    <name>W6ZS30_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683143.1">
        <property type="nucleotide sequence ID" value="XM_007684953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZS30"/>
    <dbReference type="GeneID" id="19120202"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22189"/>
    <dbReference type="HOGENOM" id="CLU_1467911_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="184" mass="19798" checksum="AD4F81FA36A29353" modified="2014-04-16" version="1">MPMGRLGREDVERSSAGSGTTMRMGMRIHDLEAQTTGSYQATGREAGCSKVYILLQETSKCNATVAQLLADNGGRQRVNRPRVVLIRLAVHYTEDWNIGVGGTCSVRDNGSLPAQTDALRRTAWCVPRAQESFVAVITWATVGPSVLVGGIMRGVESMALLLKQEKVRGESVGNPCERSFSGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSV1</accession>
    <name>W6ZSV1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_81522</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682906.1">
        <property type="nucleotide sequence ID" value="XM_007684716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSV1"/>
    <dbReference type="STRING" id="930090.W6ZSV1"/>
    <dbReference type="GeneID" id="19125885"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81522"/>
    <dbReference type="HOGENOM" id="CLU_727593_0_0_1"/>
    <dbReference type="OrthoDB" id="3789992at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887277" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="39670" checksum="466B47507E403B14" modified="2014-04-16" version="1">MASVMLGPLLLALLVQDGAAAIMAAPRAAITPAPVLKRAVTTIGYISTREYDGTTYWDTITANEQGNAIATSSNLFQICDPAKPCTFFSCSGDYVIMPSSSIFCGGESSTCSYWELATDINDKTPLTNYWCDAKTSVGGIIYRTTPEAAATNTAASTTSTRAAPSITFTSATNIATDVTSISSSGPGLGETNDGGSLTKPKKKSSTPIGPIVGGVVGGVAVLAGIIIAIWMILKRKKKNKTDTNNITQTAQVPPAAPPAVQQNAQQPPAGVQYYHEQKPVSQPQVQQVPPPQPYGHYDPNAQPAPAQPFYDPNAQTAYAQQSQAGYGAPSPDKTPAPLATGQQTHAYYADNAPISPVPQYSPSPSPAIPANVSELSSSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSW0</accession>
    <name>W6ZSW0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_91982</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686725.1">
        <property type="nucleotide sequence ID" value="XM_007688535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSW0"/>
    <dbReference type="GeneID" id="19127983"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91982"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_3_1"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000319">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF30">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04702)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="422"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="59038" checksum="A2BCADB326A99A4C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX02</accession>
    <name>W6ZX02_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OsmC family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_23903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685124.1">
        <property type="nucleotide sequence ID" value="XM_007686934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX02"/>
    <dbReference type="GeneID" id="19120511"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23903"/>
    <dbReference type="eggNOG" id="ENOG502SIRU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100936_0_0_1"/>
    <dbReference type="OrthoDB" id="4139202at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052924">
        <property type="entry name" value="OsmC/Ohr_hydroprdx_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35368">
        <property type="entry name" value="HYDROPEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35368:SF1">
        <property type="entry name" value="HYDROPEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="OsmC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="21364" checksum="07276480036FB2F5" modified="2014-04-16" version="1">MSAAQALREKQAPIKEGYRADPSSAVVTLKSTGSLDSHSITCKLSDSPAIKEAHRVAGLHQKAGGEDPSISGELCSGDMLLDALVACSGVTLKAVATALGIPIVSGTVTAEGDLDFRGTLGVDKTAPVGLTGIRLDFAVQFGEREDGREVSEEEVERLGKLTERYCVVLQTLVHKPSIGVRLVGKGGGKEEEGVKREVSHQSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYP8</accession>
    <name>W6ZYP8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase family 8 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_33674</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684617.1">
        <property type="nucleotide sequence ID" value="XM_007686427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYP8"/>
    <dbReference type="STRING" id="930090.W6ZYP8"/>
    <dbReference type="GeneID" id="19122380"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33674"/>
    <dbReference type="eggNOG" id="KOG1950">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049943_0_0_1"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000171">
        <property type="entry name" value="Glycosyl transferase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="316" mass="35662" checksum="C637D42166219D09" modified="2014-04-16" version="1">MQNTTETPSTTQAGTKSKKVWTTLITNTAYLTGLLTLDYSLKKHGSKYPLVALYTDTFPAEGHKALDERGIPKQHVKYLLPTVNKDFTNDPRFYDCWSKLTPFSLEEYDRVVQLDSDMLVLKNMDELMELELDPPSTGGKGDRVFAASHACVCNPLKKPHYPKDWIPENCAFTSQHSDPEAAQRTGAPSTAGLRMPNGGLQVVNPSKATYDLILQQLANETSMSYDFADQSLLGDLFNGRWVALPYTYNALKTMRSKGVHDAIWKDEEVKNVHYILSPKPWDEAPGKCSLEIHEWWWPINDERRAAEKSKGIDDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZU8</accession>
    <name>W6ZZU8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684222.1">
        <property type="nucleotide sequence ID" value="XM_007686032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZU8"/>
    <dbReference type="GeneID" id="19126623"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85199"/>
    <dbReference type="eggNOG" id="ENOG502R1AJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_478941_0_0_1"/>
    <dbReference type="OrthoDB" id="3776879at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="569" mass="63292" checksum="BA8E54DF4C7CDF34" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2R1</accession>
    <name>W7A2R1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_32380</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683163.1">
        <property type="nucleotide sequence ID" value="XM_007684973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2R1"/>
    <dbReference type="STRING" id="930090.W7A2R1"/>
    <dbReference type="GeneID" id="19122092"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32380"/>
    <dbReference type="eggNOG" id="KOG4628">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008264_1_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46539">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ATL42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46539:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ATL42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887345" description="RING-type domain-containing protein" evidence="11">
        <location>
            <begin position="25"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="367"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="275"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="476"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="416"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC50286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="554" mass="60013" checksum="E5B3C765BAFD3C2C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3E4</accession>
    <name>W7A3E4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_32063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682847.1">
        <property type="nucleotide sequence ID" value="XM_007684657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3E4"/>
    <dbReference type="GeneID" id="19122020"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32063"/>
    <dbReference type="eggNOG" id="ENOG502R1YM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_392304_0_0_1"/>
    <dbReference type="OrthoDB" id="3799259at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="703" mass="78668" checksum="966F087EBAFDDDD2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W7A593</accession>
    <name>W7A593_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_79781</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC51281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682206.1">
        <property type="nucleotide sequence ID" value="XM_007684016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A593"/>
    <dbReference type="STRING" id="930090.W7A593"/>
    <dbReference type="GeneID" id="19125543"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79781"/>
    <dbReference type="eggNOG" id="ENOG502QS8F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010934_1_0_1"/>
    <dbReference type="OrthoDB" id="10260946at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900237">
        <property type="term" value="P:positive regulation of induction of conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057544">
        <property type="entry name" value="Beta-prop_SPT8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23798">
        <property type="entry name" value="Beta-prop_SPT8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="8">
        <location>
            <begin position="136"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="260"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="8">
        <location>
            <begin position="460"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="328"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="434"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC51281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="673" mass="72345" checksum="280A60A8AF788C46" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNH3</accession>
    <name>W6YNH3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_107578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964132">
        <property type="protein sequence ID" value="EUC40897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692582.1">
        <property type="nucleotide sequence ID" value="XM_007694392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNH3"/>
    <dbReference type="GeneID" id="19119078"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107578"/>
    <dbReference type="HOGENOM" id="CLU_2628455_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="78" mass="8795" checksum="D583F98BC966C841" modified="2014-04-16" version="1" fragment="single">DYIFFLISSFSLPPSPSLSPTSTLNFSTPKLPNTPFSSLLPFPTSKGKQEFPNKGTIEENMNLCDKRRNKPEMINRCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPN6</accession>
    <name>W6YPN6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_31250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964301">
        <property type="protein sequence ID" value="EUC39625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693861.1">
        <property type="nucleotide sequence ID" value="XM_007695671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPN6"/>
    <dbReference type="STRING" id="930090.W6YPN6"/>
    <dbReference type="GeneID" id="19121828"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31250"/>
    <dbReference type="eggNOG" id="ENOG502R216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035067_0_0_1"/>
    <dbReference type="OrthoDB" id="3776883at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="423" mass="47799" checksum="246FF13229B5FD1C" modified="2014-04-16" version="1" fragment="single">MSLNDLRNGIASYGAGQQLDALPSADSMTWAPQPGANPAFSLLIGSLDGQQILAYLTRYGEKPREVRYCTRPPPDRPSNKPSSSMSTVTQDDVMKASLLPPFKYLAENSKPMKRKFSMLIRWYFLIKGYIDGLEGDQGDFCKRFSSAVKRIEEEKHDEEDGTQNRARRNREAIEESPEPEDADSTYTLRSNSRTGKTHVINGDKSEPQSPSVRSSRELRNSKGNHDLERLLEYLKDHNALYLLDNLPEVSEIQFVGQTSIPEAQPMKLFVGREAKSGDDIYAYMVSLARGFHEVRFYVQTAHDEEPMKTETVSKQRLIHPFSKCYPKQPCILEQSDRARLTLMVKFYFISAGIATDCVLKETKKYPERLRVALDYIADRMGPAAAKPPSHTKKDDDDDTAATTAVLNNPPKHRLSSESSYIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQG7</accession>
    <name>W6YQG7_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110695</name>
    </gene>
    <organism evidence="1 2">
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQG7"/>
    <dbReference type="GeneID" id="19119642"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110695"/>
    <dbReference type="eggNOG" id="ENOG502SV6Y">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122933_1_0_1"/>
    <dbReference type="OrthoDB" id="3709982at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <source>
            <dbReference type="EMBL" id="EUC39743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="117" mass="13543" checksum="659FEBFA4C236197" modified="2014-04-16" version="1">MSHIAPKRVVLRCREQYFREHGRMVETFLESQNLLDIEDYGIHICGDPSSPTTLYLVLDLYCREVPIVDLSNLELQVFKVSKNNTFTFKDLGENASKKAYERSLTLDWGANQSNQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQH0</accession>
    <name>W6YQH0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC39748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQH0"/>
    <dbReference type="GeneID" id="19119639"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110686"/>
    <dbReference type="HOGENOM" id="CLU_1115657_0_0_1"/>
    <dbReference type="OrthoDB" id="10444631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="252" mass="26433" checksum="E837FAF608BB25D4" modified="2014-04-16" version="1" fragment="single">LERAKGPGKSKCNSKTNEPVQTGGGIARPGTFILNRAGLMASKNAGELEPGPESMEVIDIEPSGDNPEDGNTEEAAILVSSQDSPNPNTAHTARKTGPANNQTTIPSWFIFTGSSLGSALNTASSASNKKDARSPATGEKVGQTKPNGKKGNATSTTAEGKKRVRTTSESSPRGFRFRRRIGSYDSATADPPEESTGSPQGKATATVDVAGVDGRKKGKARAQTRESDAEDRDLSEYIDESESMWESDASVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR22</accession>
    <name>W6YR22_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CWF21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_30917</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964200">
        <property type="protein sequence ID" value="EUC40080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR22"/>
    <dbReference type="STRING" id="930090.W6YR22"/>
    <dbReference type="GeneID" id="19121770"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30917"/>
    <dbReference type="eggNOG" id="KOG1869">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067891_2_1_1"/>
    <dbReference type="OrthoDB" id="10267305at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21372">
        <property type="entry name" value="cwf21_CWC21-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08312">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01115">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="8">
        <location>
            <begin position="54"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="94"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="183" mass="21543" checksum="857FDED5162455AF" modified="2014-04-16" version="1">MADNVGLTTPRGSGTSGYVQKNRSLLRPRDKIQPYPKDWDQAKHRPRQPDAEILEHEAKREIEVKVLELRDKLEDEGVDEDEIDDQCEALRRKLDQERKDGRDLGPNAKRLKSHQVHDLAKAKMEESERLRKALGISEDYEEGSHWRKQEERMRESLAKREAEDEEKLEKAKEARRYKEDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS22</accession>
    <name>W6YS22_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Han J."/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964120">
        <property type="protein sequence ID" value="EUC41100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692387.1">
        <property type="nucleotide sequence ID" value="XM_007694197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU60"/>
    <dbReference type="GeneID" id="19118978"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107087"/>
    <dbReference type="eggNOG" id="ENOG502S0Y3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039534_1_1_1"/>
    <dbReference type="OrthoDB" id="507128at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051262">
        <property type="entry name" value="SMP-30/CGR1_Lactonase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47572:SF4">
        <property type="entry name" value="LACTONASE DRP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47572">
        <property type="entry name" value="LIPOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889235" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="2">
        <location>
            <begin position="65"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="455" mass="48979" checksum="6D61BF6DD0CEB977" modified="2014-04-16" version="1">MRLFKLGLAIFPSIIYARTPLPISNHTALLTSTVADATTSKLSEPVHTSIPTSCDGVPNFAFPVNTAKGWKATKVAGGLTQPRGLSFDSSGNLLVVQNGVGITAHKMLLNGCLEPSKIVIAQRDLNHGIVFSQDGKTLYASSATRVFAWAYDTATMRVSENSTTIVTGMDTGGHLTRSLATPPKHPDLLLVSHGSNGNIDYGSIDIKTGRACIKVFNTTTIPLNGYDYTTSGTQLGYGLRNEVGLAFDTSSHLWGVENSADELRRTINGVSTDIHNDNPADELNYIGDPSRENKDWYGYPTCFTVFSPSTIPGGNFTIGDQFVLEPNATFTDTTCRERSVAPRIAFPAHSTPLDAKFNAGFSALYVTLHGSWNRDPPVGFKVIQVPFGLADGGFGPTRGSNAPEAWEDVLWNGRVDTCSKTSCFRPVGLAVDRWGRVYVSSDSSVEGEVVMLRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWN5</accession>
    <name>W6YWN5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ca2+-modulated nonselective cation channel polycystin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_99878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964019">
        <property type="protein sequence ID" value="EUC43787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689699.1">
        <property type="nucleotide sequence ID" value="XM_007691509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWN5"/>
    <dbReference type="GeneID" id="19129555"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99878"/>
    <dbReference type="eggNOG" id="ENOG502SFF8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035522_0_0_1"/>
    <dbReference type="OrthoDB" id="5377012at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="42915" checksum="EA8C6FCE327EBED4" modified="2014-04-16" version="1">MATAEAASRPHDRHTTRKRPFAGWMKRLANLKPSSSDAPGKKSTTTKKALTKNNPYPQSGYMTTSTNAPDDSISVSTAATPRSNASCTSVEETAAERPQRVEKSNKSTAPTVATLPETLNSTRSKAETGGSNFVAGGSTFSSPHGSEHSLTTTLTTIQSTAPSNVLNIGQAQQQNNANNSLATPVHFSHQFPTSPPPSAIPPHMAVQQQPNSYQGATANNILTDNASILTLASSSKRRRRNSVDTNASMRALAPSSHYGGSRESLPLSVLSANPETIYSPSNRPNNVGAFVNAERASVYSASGVTAPAFSTDRNSYYANKQADGLSVRSGLLGHGRTDSISSMRATPTSPLASPRDPVGPGRISRKSSEWKEAREASDEDEVPASPIVEEHEEKANTQSKSDPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWX1</accession>
    <name>W6YWX1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_104527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964075">
        <property type="protein sequence ID" value="EUC42050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691444.1">
        <property type="nucleotide sequence ID" value="XM_007693254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWX1"/>
    <dbReference type="STRING" id="930090.W6YWX1"/>
    <dbReference type="GeneID" id="19118524"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104527"/>
    <dbReference type="eggNOG" id="ENOG502RZSA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036110_1_3_1"/>
    <dbReference type="OrthoDB" id="423498at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052988">
        <property type="entry name" value="Oryzine_lactonohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064:SF2">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="1">
        <location>
            <begin position="133"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="342" mass="37659" checksum="F74452F16DBD2F5B" modified="2014-04-16" version="1">MSPSPSWLRIYDSAANDLFGSNPKLEVLLEDDKCPFAHEAGVFLPEENCLFVTSNQYQHPSTGKTHIHVSRIQLPADSTSTAAKYAEVSVKNVHMANGGVNYQDGILFCSQGTLDTPGGIAFMRCSSKPFSATTTYEAKLLITDFHGRPFNSPNDVVVHSDGAIWFTDPNYGFEQKIRPKPRLPNQVYRFDPATGSIRAVADGFSRPNGICFSPDERVVYVTDTDWIHGDGETDDARVSHIYAFDVQTYSGQPFLTNRRLFAMADTGVPDGIKCDLDGNVYSGCGDGLNIWSPGGVLLAKILIDGGVANFCFGKDGQVFLLNEYKLWRLQLHERCKGALLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX28</accession>
    <name>W6YX28_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquitin-conjugating enzyme E2 2</fullName>
            <ecNumber evidence="2">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">E2 ubiquitin-conjugating enzyme 7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Ubiquitin-protein ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_29224</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="2"/>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691378.1">
        <property type="nucleotide sequence ID" value="XM_007693188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX28"/>
    <dbReference type="STRING" id="930090.W6YX28"/>
    <dbReference type="GeneID" id="19121464"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29224"/>
    <dbReference type="eggNOG" id="KOG0426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_10_1_1"/>
    <dbReference type="OrthoDB" id="19692at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990389">
        <property type="term" value="C:CUE1-UBC7 ubiquitin-conjugating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000837">
        <property type="term" value="C:Doa10p ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000839">
        <property type="term" value="C:Hrd1p ubiquitin ligase ERAD-L complex"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180027">
        <property type="term" value="P:inner nuclear membrane-associated protein degradation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23796">
        <property type="entry name" value="UBCc_UBE2G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000008">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0882">Thioester bond</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="17">
        <location>
            <begin position="4"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="15">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00077195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC42095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="165" mass="18553" checksum="5C7F1964D208EB33" modified="2014-04-16" version="1">MASTAAKRLFKEYRALSSDPPEGITAGPINEDDMFIWEALIQGPEGTPFEGGVFPAELRFPKDYPLAPPKMKFITDMWHPNVYPNGEVCISILHAPGEDPMQYEQASERWSPIQSVEKILISVMSMLAEPNDESPANVDAARMWREKRAEYESIVRANVRKSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX51</accession>
    <name>W6YX51_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sec39 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_29195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964072">
        <property type="protein sequence ID" value="EUC42120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX51"/>
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    <dbReference type="OrthoDB" id="3434013at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013244">
        <property type="entry name" value="Sec39_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40787:SF3">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40787">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08314">
        <property type="entry name" value="Sec39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec39" evidence="6">
        <location>
            <begin position="16"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="874"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="932" mass="104181" checksum="9432C0D6697AD67D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX84</accession>
    <name>W6YX84_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_109573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964194">
        <property type="protein sequence ID" value="EUC40134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693344.1">
        <property type="nucleotide sequence ID" value="XM_007695154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX84"/>
    <dbReference type="GeneID" id="19119458"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109573"/>
    <dbReference type="HOGENOM" id="CLU_2711491_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="73" mass="8182" checksum="C05FB6796658A332" modified="2014-04-16" version="1" fragment="single">GPIKAVNACPAWWLWLRLSCICIAAGANELRLARVQPPLPPAMLFFPFLLFLTVLSHSLLIPLLLTNHWHGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXR8</accession>
    <name>W6YXR8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial cytochrome c oxidase assembly factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_103721</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PET100 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964064">
        <property type="protein sequence ID" value="EUC42360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691138.1">
        <property type="nucleotide sequence ID" value="XM_007692948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXR8"/>
    <dbReference type="STRING" id="930090.W6YXR8"/>
    <dbReference type="GeneID" id="19118363"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103721"/>
    <dbReference type="eggNOG" id="ENOG502S1QV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156745_2_0_1"/>
    <dbReference type="OrthoDB" id="18175at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018625">
        <property type="entry name" value="Pet100"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33968">
        <property type="entry name" value="PROTEIN PET100 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33968:SF1">
        <property type="entry name" value="PROTEIN PET100 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09803">
        <property type="entry name" value="Pet100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC42360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10693" checksum="2EE53C8BE3EE0834" modified="2014-04-16" version="1">MAGPNLEVFKFGMYILFPISIMYYFGTNLDGKFTVPDFWPKPGQTHKIPYDRDEIAKELERIKARNLENKRRREERERLREMGGQPREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXX6</accession>
    <name>W6YXX6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964061">
        <property type="protein sequence ID" value="EUC42430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691036.1">
        <property type="nucleotide sequence ID" value="XM_007692846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXX6"/>
    <dbReference type="STRING" id="930090.W6YXX6"/>
    <dbReference type="GeneID" id="19118309"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103473"/>
    <dbReference type="eggNOG" id="ENOG502SS11">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096872_4_1_1"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020915">
        <property type="entry name" value="UPF0311"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37315:SF1">
        <property type="entry name" value="UPF0311 PROTEIN BLR7842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11578">
        <property type="entry name" value="DUF3237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="156" mass="17121" checksum="C2A7E787C4E3524C" modified="2014-04-16" version="1">MAQDEEPVPPQLTLLYRMEALLAPPINVPDIPYGQTRSIIPIIGGTFKGPRLSGKILNIGADWLLVDNSGKTRPDTRYVLQTDAGEIIYIQTEGLPPKDNNDSTPNMLRGKFETSRNNTVAWLNDVAAIAVLRVGKPNTVLIDMWEATPAPESSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY77</accession>
    <name>W6YY77_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_69996</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964007">
        <property type="protein sequence ID" value="EUC44287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689196.1">
        <property type="nucleotide sequence ID" value="XM_007691006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY77"/>
    <dbReference type="GeneID" id="19125148"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_69996"/>
    <dbReference type="eggNOG" id="KOG1153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_4_1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012655492" description="Peptidase S8/S53 domain-containing protein" evidence="7">
        <location>
            <begin position="16"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="41"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="174"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC44287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="49758" checksum="A39766911CBA9911" modified="2014-04-16" version="1" fragment="single">MRYILISALSALAAASPTFTATGNDVAPLISSGSAVVVPDRYIVVFKKDVKDSSQHYDWLQSIQPNSKDRMELRKRSGDVFTGLKHTYEMSGFMGYSGHFSEETVKSIQRHSDIDYIERDSELYLDENDSEINNDPCGEHMIQRNASWGLARISQRNGLKSETWNNHLYAADGGEGVDVYVIDTGTNIEHVDFEGRATRFKRVLENEPEEDIRGHGTHVSGTLVGKRHGVAKKANLYSLNVFGSSKTVRTSDTILAIQYAVKGHELAVKSGKKGFKGSVVNMSLGGPGPATAQKQAIDNAVRAGLHFAVSAGNDNIDACTRHPGGFDNVITVGASNLQDQRAYFSNHGKCVDIFAPGDRILSTWIGHKYATNLRSGTSMATPHVAGLLAYMLSLQPAKNSAYSGVDITPQKLKANLLAIGTVDALGPLPSETKNILLWNGGGCSNFAKIIEHGGYVVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYU4</accession>
    <name>W6YYU4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_102684</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964050">
        <property type="protein sequence ID" value="EUC42748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690726.1">
        <property type="nucleotide sequence ID" value="XM_007692536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYU4"/>
    <dbReference type="GeneID" id="19118136"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102684"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010365_5_1_1"/>
    <dbReference type="OrthoDB" id="17725at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF28">
        <property type="entry name" value="FRP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="378"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="102"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="650" mass="73625" checksum="C3A659536EB91AAF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ83</accession>
    <name>W6YZ83_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_102217</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964045">
        <property type="protein sequence ID" value="EUC42905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690567.1">
        <property type="nucleotide sequence ID" value="XM_007692377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZ83"/>
    <dbReference type="GeneID" id="19118034"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102217"/>
    <dbReference type="eggNOG" id="ENOG502QVC1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011017_0_0_1"/>
    <dbReference type="OrthoDB" id="5600212at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF10">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="630"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="709"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="836" mass="93222" checksum="5EED558F5A55F402" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZH6</accession>
    <name>W6YZH6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_26978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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                <person name="Wu D."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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    <dbReference type="AlphaFoldDB" id="W6Z0W6"/>
    <dbReference type="GeneID" id="19118866"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106462"/>
    <dbReference type="HOGENOM" id="CLU_2305801_0_0_1"/>
    <dbReference type="OrthoDB" id="3680191at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="102" mass="11122" checksum="64867A78353122A4" modified="2014-04-16" version="1">MASQALVLATNSTLQQKPAPIVPHNSPTQQQQQKPSANKSGGFCLKKGLDSLTEMLERKIDHQILLAKTRAHAASSSQETPAGRDSKHVHWETRSKLQQTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1R6</accession>
    <name>W6Z1R6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_27658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689555.1">
        <property type="nucleotide sequence ID" value="XM_007691365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1R6"/>
    <dbReference type="GeneID" id="19121161"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27658"/>
    <dbReference type="HOGENOM" id="CLU_1004686_0_0_1"/>
    <dbReference type="OrthoDB" id="3691720at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="277" mass="29204" checksum="AE89CA80C879381C" modified="2014-04-16" version="1">MTLPGPQAKPQVNSNPDFKLPGLPASKSTLSNISNTTAAAVLGGILCHNLAFDKGVLVPQPADFHHGLGLANSVLPIGALNGHAVHDWWLQSMEDAPFVVASVRGWIVSIPPPVHRLVTIHAVGYAGNTLFPYLLDDAAPEKRAAEPQAAGDNVLCLVRKCLALGAAVWVGDGRLAGVFGLPLLDGTDDIGECVQYSGVVVGRGIGRGEAPSVLLESCPPRLWTRRGTQRRTQWLSIWGCSAPLAKAVIVVTPLDMDEPVIPVTPGQARGLLSVRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2U2</accession>
    <name>W6Z2U2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome production factor 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ribosome biogenesis protein RPF2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_37888</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
            <location evidence="1 4">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RPF2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689230.1">
        <property type="nucleotide sequence ID" value="XM_007691040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2U2"/>
    <dbReference type="STRING" id="930090.W6Z2U2"/>
    <dbReference type="GeneID" id="19123346"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37888"/>
    <dbReference type="eggNOG" id="KOG3031">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049783_0_0_1"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039770">
        <property type="entry name" value="Rpf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728">
        <property type="entry name" value="BRIX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728:SF0">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="28"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="274"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="328" mass="37692" checksum="BDA2DBFCCE2F638A" modified="2014-04-16" version="1">MLKQAKPKNARAKREMKKREPQQNENPKTTLFVSGQKTSQILKLAVADLTTIKRPFVERFTKKNDIHPFDDASSLEFFSQKNDTSLLVLSLHSKKRPHCLTLARTFSYKMLDMLELYINPETFRTLQQFKNKKPSIGLKPMISFHGTVFEDPNQTKYTLAKSLFLDFFKGQDTNEIDVEGLQYLASISAEEPTDELPNPPIHLRFYLLRTKRSGQKLPRIEVEEMGPRMDFTLGREMFPDPDMLKQAMKTPKGAEARTKKNIDMNAMGDKTAKVHVGKQDFGNLQTRKMKGLKRGRNEDDDDEEAGVEDSGSDDDDEVEEKTPKKMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z300</accession>
    <name>W6Z300_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_27365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964007">
        <property type="protein sequence ID" value="EUC44305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689180.1">
        <property type="nucleotide sequence ID" value="XM_007690990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z300"/>
    <dbReference type="GeneID" id="19121111"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27365"/>
    <dbReference type="HOGENOM" id="CLU_1474931_0_0_1"/>
    <dbReference type="OrthoDB" id="10364082at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="183" mass="20295" checksum="C74E9E24645C3989" modified="2014-04-16" version="1">MADRHHLAWRPWLLVAAEAGMRKSLTTVTPPALKHVFSKPGHLDAKQVVPRRTVIKSKRRMRHDGGGQQCKARRGCAGGAILRTTIPLHTQRRSREPHVLFHHQPCHGSGTPDTTLDPRPSLRTRHGARRWKLRIVPSLIPETTRPSQAVCSPSKSTRRRRQGSRGRAVHDAGTARTAGTAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z307</accession>
    <name>W6Z307_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polyketide synthase methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689344.1">
        <property type="nucleotide sequence ID" value="XM_007691154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z307"/>
    <dbReference type="STRING" id="930090.W6Z307"/>
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    <dbReference type="eggNOG" id="ENOG502QQW3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045794_0_0_1"/>
    <dbReference type="OrthoDB" id="506498at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000554">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43832">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43832:SF1">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="40167" checksum="1463BF3A17BCB20E" modified="2014-04-16" version="1">MNYISNIVNSDAVINPLLDNGYLPHAVIRVGIRRQLADRLQSIATTSLESAYETKMKYVKLLRERPIAIETATANEQHYEVGTSVLKGMLGPRMKYSACLYEKGGETLAQAEIAMMRLYIERAELKDGMSILDLGCGWGSASLFMAEMFPNSKITGFSNSRTQKEYIDSVAVSKGLKNLTIITGDVVDYEFQPEAYDRVISIELFEHMKNYQLLLRKVGSALKPGGKLFVHIFAHCTTPYDFEEGWMTEHFFTGGTMPSADLLLYFQDDLRVKNQWWVSGMHYSKTCEDWLVTMLKNKDSIWKGLVETYGEEGALTWWNRWQVFHMACSELFRWNGGDTWGVSHYLFEKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3T4</accession>
    <name>W6Z3T4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_29081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964067">
        <property type="protein sequence ID" value="EUC42269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691207.1">
        <property type="nucleotide sequence ID" value="XM_007693017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3T4"/>
    <dbReference type="GeneID" id="19121435"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29081"/>
    <dbReference type="eggNOG" id="ENOG502SJ1N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008828_3_0_1"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="678"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="694"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="758" mass="83820" checksum="19AFE30B4592B8A3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3V5</accession>
    <name>W6Z3V5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">60S ribosomal export protein NMD3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_103859</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NMD3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964066">
        <property type="protein sequence ID" value="EUC42294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691184.1">
        <property type="nucleotide sequence ID" value="XM_007692994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3V5"/>
    <dbReference type="STRING" id="930090.W6Z3V5"/>
    <dbReference type="GeneID" id="19118388"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103859"/>
    <dbReference type="eggNOG" id="KOG2613">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027444_2_0_1"/>
    <dbReference type="OrthoDB" id="203821at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039768">
        <property type="entry name" value="Nmd3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007064">
        <property type="entry name" value="Nmd3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048899">
        <property type="entry name" value="NMD_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048898">
        <property type="entry name" value="OB_NMD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746:SF2">
        <property type="entry name" value="60S RIBOSOMAL EXPORT PROTEIN NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04981">
        <property type="entry name" value="NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21193">
        <property type="entry name" value="NMD_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21192">
        <property type="entry name" value="OB_NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nmd3 N-terminal" evidence="9">
        <location>
            <begin position="19"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 SH3" evidence="11">
        <location>
            <begin position="251"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 OB-fold" evidence="10">
        <location>
            <begin position="315"/>
            <end position="405"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="466"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC42294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="508" mass="57976" checksum="2EF777558E4A2391" modified="2014-04-16" version="1">MTDAQSFAPAPKNAATILCADCGAPVDGTISGAFCYDCIKLKTDVTGGIQREAILLMCRDCDRWLSPPSTWVVAPPESRELLALCLRKLRGLNKLRIIDASFIWTEPHSRRIKVKITVQSELNEGAIMQQTFEVEYTQNYNQCPDCAKSYTHNTWRACVQVRQKVPHKRTFLYLEQLILKHGAHKDTINIKEVHDGIDFFFAQRNHAVAFCDFLKAVIPVNIKRSEELISHDIHTSTKNYKFSFSCEIVPICKDDLVVLPIPLAKKIGNISPLTLCSRIGTSVQLLDPATLQTADVATDIYWRTPFRPLADVQELTEFVVLDIEPLGKQSGRNFLAEATVARASDMGVNDTTYYCRTHLGGILHVGDSVMGYLLANTNFNNDLFDVLEQNNKYASAIPDVVLVKKYYQRSRKSKNKRNWRVKRMHKEEGEMLPRKQDQEKMERDFEMFLQDVEEDQELRQTMALYKAQQQRDADAMETESSLGDDEDEGIQIPMDQLLDDFEDMKMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4D8</accession>
    <name>W6Z4D8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_54816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964060">
        <property type="protein sequence ID" value="EUC42484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691024.1">
        <property type="nucleotide sequence ID" value="XM_007692834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4D8"/>
    <dbReference type="GeneID" id="19124631"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_54816"/>
    <dbReference type="HOGENOM" id="CLU_2984398_0_0_1"/>
    <dbReference type="OrthoDB" id="10288890at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="58" mass="6206" checksum="EE4BAC9A3DB4A0C8" modified="2014-04-16" version="1" fragment="single">MLAHYANLPTVSSVIAFNRRNKSSGLDALGRQLAALKSRDLTLSPSASGKISVFEVDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4M4</accession>
    <name>W6Z4M4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="13">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_39406</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:21249"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="13"/>
    <dbReference type="EMBL" id="KI964057">
        <property type="protein sequence ID" value="EUC42564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690926.1">
        <property type="nucleotide sequence ID" value="XM_007692736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4M4"/>
    <dbReference type="STRING" id="930090.W6Z4M4"/>
    <dbReference type="GeneID" id="19123679"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39406"/>
    <dbReference type="eggNOG" id="KOG0216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_5_1_1"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000016">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000007">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009674">
        <property type="entry name" value="Rpa2_dom_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06883">
        <property type="entry name" value="RNA_pol_Rpa2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="18">
        <location>
            <begin position="44"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="233"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="19">
        <location>
            <begin position="496"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase I subunit RPA2" evidence="20">
        <location>
            <begin position="600"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="15">
        <location>
            <begin position="706"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="1087"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="932"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF06883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC42564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1213" mass="135550" checksum="2EC614046BBA6F97" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5Q3</accession>
    <name>W6Z5Q3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_25001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686399.1">
        <property type="nucleotide sequence ID" value="XM_007688209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5Q3"/>
    <dbReference type="GeneID" id="19120680"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25001"/>
    <dbReference type="eggNOG" id="ENOG502SW9F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131535_2_0_1"/>
    <dbReference type="OrthoDB" id="3500395at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15533" checksum="7DD04D1555927FF3" modified="2014-04-16" version="1">MPNDPISLATLSTLPSTYDPNKPVYMLNLWKYRKEASYLPEHAHLAGDACTGQEALGRYRTAIAPLLPPNTSVIFSSTVLAKILVAENEDWDFVAILRYETLEGFKKAIESKEYREEVEPHRLAGLEDGRLIALDKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6L1</accession>
    <name>W6Z6L1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">isopentenyl-diphosphate Delta-isomerase</fullName>
            <ecNumber evidence="4">5.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_5360</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>isopentenyl diphosphate = dimethylallyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23284"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="5.3.3.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:23285"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IPP isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="4"/>
    <dbReference type="EMBL" id="KI963984">
        <property type="protein sequence ID" value="EUC45453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688020.1">
        <property type="nucleotide sequence ID" value="XM_007689830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6L1"/>
    <dbReference type="STRING" id="930090.W6Z6L1"/>
    <dbReference type="GeneID" id="19124589"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5360"/>
    <dbReference type="eggNOG" id="KOG0142">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060552_0_2_1"/>
    <dbReference type="OrthoDB" id="510307at2759"/>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045337">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009240">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02885">
        <property type="entry name" value="NUDIX_IPP_Isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000012">
        <property type="entry name" value="Isopentenyl-diphosphate Delta-isomerase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011876">
        <property type="entry name" value="IsopentenylPP_isomerase_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02150">
        <property type="entry name" value="IPP_isom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885:SF0">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0752">Steroid biosynthesis</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="13">
        <location>
            <begin position="86"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC45453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="265" mass="30415" checksum="1A4EF8C77446CEA6" modified="2014-04-16" version="1">MSTVETVTQHPVITAENVLRLFPEVNTSLIGGSHNSATDDNALQGYDEEQIRLMDEVCIVLDNDDLPIGSATKKLCHLMENIDKGLLHRAFSVFLFDSKNRLLLQQRATEKITFPDMWTNTCCSHPLGIPGETGVGLEESIQGVRRAAVRKLNHELGIKSEQVPIDDFKFLTRIHYKSPSDGVWGEHEIDYILFMKADVDLDINPNEVRDSKWVSQEDLKTMFKDKSLKFTPWFKLICESMLFEWWNHLDSGLEKYLGETEIRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6W7</accession>
    <name>W6Z6W7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_101233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964034">
        <property type="protein sequence ID" value="EUC43289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690206.1">
        <property type="nucleotide sequence ID" value="XM_007692016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6W7"/>
    <dbReference type="GeneID" id="19117833"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101233"/>
    <dbReference type="HOGENOM" id="CLU_2312690_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="100" mass="11318" checksum="4419040BBA52EB31" modified="2014-04-16" version="1" fragment="single">LGHRWRDLGRGSYRAHDAAFSPGFSHRRHGSSWWAVAGEMWLMHATPRRGEAGGNGCGCGWAVAYVMFMGNRNRNRKYYYMLLYIHSSTSLLHSAMTLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6X7</accession>
    <name>W6Z6X7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Proline dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_101185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the proline oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2 5"/>
    <dbReference type="EMBL" id="KI964033">
        <property type="protein sequence ID" value="EUC43304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690170.1">
        <property type="nucleotide sequence ID" value="XM_007691980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6X7"/>
    <dbReference type="STRING" id="930090.W6Z6X7"/>
    <dbReference type="GeneID" id="19117823"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101185"/>
    <dbReference type="eggNOG" id="KOG0186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018202_0_1_1"/>
    <dbReference type="OrthoDB" id="5464at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF0">
        <property type="entry name" value="PROLINE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline dehydrogenase" evidence="6">
        <location>
            <begin position="173"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC43304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="468" mass="52127" checksum="7A69E5233BB0D6A1" modified="2014-04-16" version="1">MFRPRLSGKGLQHVYGRRSLTHGFGRPGIRLSSTTTLPRTRETARHAPAQQRVQYPLSVMPTHMLLRSLFVATISSNKFLLVPSLNLLSFLSKPNRSFLFNVDRNPILKAILKRTLYNQFCAGETEKETQACVKQLKNLGFKGVILTYAKEMVFDHKAGSAKDHGLEKGVDEKVVVHDADIESWRQGTLQTLDLISKGDILALKTTGGGPAVSAAFSQGNLPPQQMLSALEELATKCKERGIQIIIDAESQHWQHGIARTTLELMRKFNREGKAVIYNTYQAYLKETSAVVQQHMAEAEKDGFTLGLKLVRGAYILSDNRALIHDTKEDTDNAYNTIAQGALRQRLGPFGGKDRPFPSVNLLLASHNRESVMAASALHRQRLEAGLPTVPVAYGQLHGMSDEVSFSLLAEKDKGGVSPEVFKCTTWGSIGECVGYLLRRAVENRDAVLRTKDEFAALRKEARRRFMWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z799</accession>
    <name>W6Z799_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_10351</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964333">
        <property type="protein sequence ID" value="EUC39561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693920.1">
        <property type="nucleotide sequence ID" value="XM_007695730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z799"/>
    <dbReference type="STRING" id="930090.W6Z799"/>
    <dbReference type="GeneID" id="19118320"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10351"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC39561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="57666" checksum="78EE0C46AADDA52D" modified="2014-04-16" version="1">MTVLSKFPFDLGAIRQEHLLLCLPTIGAIIVLRVVTGVVYNLFLHPLKKFPGPKLAAATNLYYFYRVFRGEEASWVTECHEKYGEVVRTAPGKLSYISPQAWKDITGHRTGARQEFLKDTKFYSPDLNGDYSVVAEPTSETHGQVRRVFANAFSDRALRLQEPLIYHHVNKLNKILDKTIAADPETHIDLVRMYNCTTFDIMGDLTFGEPLGMLDTGKYTQWVRAVFESIKVLNMFRLAKQYPSAGFLLKTFMPPSLRGKEVEHFQHSIERVDKRLAKGTDIGKSDIWKLVLENQKVQLPLSKMHANASAFMVAGTETTATLLSGMTYLLLTNPEKLKKVVEEVRALSKEDLSLEVLPRLPYLSACFQETFRCYPPVAIGTPREVPQGGAVICGEWVPEKTSVAIAQKAAYSSALNFKDPQDFVPERWLPGSGYNTDRKDVLQPFSFGPRNCIGKNLAYHEMRVIGAMILWNYDLELCPESKSWMDQKVYTLWEKPELMVKLRPVQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7R1</accession>
    <name>W6Z7R1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Histidine biosynthesis trifunctional protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <ecNumber evidence="19">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-ATP pyrophosphohydrolase</fullName>
                <ecNumber evidence="19">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Histidinol dehydrogenase</fullName>
                <shortName evidence="19">HDH</shortName>
                <ecNumber evidence="19">1.1.1.23</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_24317</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 19">In the C-terminal section; belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="19"/>
    <dbReference type="EC" id="3.6.1.31" evidence="19"/>
    <dbReference type="EC" id="1.1.1.23" evidence="19"/>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685657.1">
        <property type="nucleotide sequence ID" value="XM_007687467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7R1"/>
    <dbReference type="STRING" id="930090.W6Z7R1"/>
    <dbReference type="GeneID" id="19120570"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24317"/>
    <dbReference type="eggNOG" id="KOG2697">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006732_0_0_1"/>
    <dbReference type="OrthoDB" id="1703565at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11546">
        <property type="entry name" value="NTP-PPase_His4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1080:FF:000002">
        <property type="entry name" value="Histidine biosynthesis bifunctional protein HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1300:FF:000001">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.810:FF:000002">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000050">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000001">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="entry name" value="Phosphoribosyl-AMP cyclohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016298">
        <property type="entry name" value="Histidine_synth_trifunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF2">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS TRIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001257">
        <property type="entry name" value="His_trifunctional"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="HisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16 19" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15 19" id="KW-0520">NAD</keyword>
    <keyword evidence="10 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphoribosyl-AMP cyclohydrolase" evidence="20">
        <location>
            <begin position="216"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR001257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC47757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="868" mass="92515" checksum="6BB550B083356802" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z811</accession>
    <name>W6Z811_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA ligase</fullName>
            <ecNumber evidence="7">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_27882</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="7"/>
    <dbReference type="EMBL" id="KI964022">
        <property type="protein sequence ID" value="EUC43684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689794.1">
        <property type="nucleotide sequence ID" value="XM_007691604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z811"/>
    <dbReference type="STRING" id="930090.W6Z811"/>
    <dbReference type="GeneID" id="19121198"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27882"/>
    <dbReference type="eggNOG" id="KOG0967">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005138_1_1_1"/>
    <dbReference type="OrthoDB" id="206088at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
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            <begin position="856"/>
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            <begin position="1"/>
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            <end position="76"/>
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            <dbReference type="ARBA" id="ARBA00007572"/>
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        <source>
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        <source>
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            <dbReference type="EMBL" id="EUC43684.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="883" mass="97804" checksum="4770249CF9D85A9E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8J2</accession>
    <name>W6Z8J2_COCMI</name>
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        <recommendedName>
            <fullName evidence="13">60S ribosomal subunit assembly/export protein LOC1</fullName>
        </recommendedName>
    </protein>
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        <name evidence="11" type="ORF">COCMIDRAFT_6729</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11 12">ATCC 44560</strain>
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        <text evidence="1">Required for efficient assembly and nuclear export of the 60S ribosomal subunit.</text>
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            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
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            <begin position="1"/>
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        </location>
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        <location>
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        </location>
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        </location>
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        </location>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="22086" checksum="020AD5636675D8F0" modified="2014-04-16" version="1">MGATKPASKGKGAKGKSGGSSSKSSKSKSKPTGSAPEGISKRKQKSLSLAKPGGEQKTKSIVSRDGKKKKRVYTEKELDIPALNGIIPAGIAKPKGVKKGKKFVDDPASMMAIMSVVNAEKEGHLESKIAKARQLEEIREAKRKEAEARKEDKEAKFEERKQDLKKKKRKRHSEPSAKSDEGDKIKEKERKFKQKKRVSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8L6</accession>
    <name>W6Z8L6_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_99657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964017">
        <property type="protein sequence ID" value="EUC43879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="Low_temperature_requirement_A"/>
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        <property type="entry name" value="BLL5714 PROTEIN"/>
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    </dbReference>
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        <property type="entry name" value="BLL5714 PROTEIN"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </evidence>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </feature>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="334" mass="37118" checksum="118DFB939E92E09A" modified="2014-04-16" version="1">MTLKSDVTVDASKFDRSTIDKQTLEFNDRLIKIWADGPRWYEVGAAEYRKMRWEGKTPLPKPIVLPEGANGALPSREAGREIPYRVFKPSSGKSNGIHMHIHGGGWVLMSEAYQDPYLKYMADHFDVTVVSIGYRLAPEDPWPAGAEDCYDAAEWLVKNGPTVFGGDLMFTGGESAGGHLACLVALHLLETMPEFAFKGLLLHFGCFDMSSFLPHVLHHETHLVIDHDVMKSYIDALLPNTTEEQRRDPSISPFWADLRGKKLPPALFTCGSEDPLLDDSVMMGSKWAMWGNESIVKIYHGAPHGFIGFPPGTIKAVQDALDDTEAFVRAKRGS</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        </location>
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        <location>
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        </location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="95" mass="10635" checksum="9ACCF50C4410EC46" modified="2014-04-16" version="1">MALRNLFKNDLVLVSTNLAVVAGVATLLGSRVERKLDRMEKEQEARRDEIEGTTRGHVGLIEDSLDRIEGKPNAGKQDKLYNQRTRDTKGVEDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9L9</accession>
    <name>W6Z9L9_COCMI</name>
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        </submittedName>
    </protein>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964009">
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    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z9L9"/>
    <dbReference type="GeneID" id="19129345"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98854"/>
    <dbReference type="HOGENOM" id="CLU_2729029_0_0_1"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="72" mass="8594" checksum="97A00F65EFA44B74" modified="2014-04-16" version="1" fragment="single">MRQEFFLENKDTEDFDYTKHGNDRHINANDSARSDKTIDTVTFNNRMDMAAELEQVQNQLQMSEMQNKHLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9R7</accession>
    <name>W6Z9R7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_98724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689253.1">
        <property type="nucleotide sequence ID" value="XM_007691063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9R7"/>
    <dbReference type="GeneID" id="19129318"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98724"/>
    <dbReference type="HOGENOM" id="CLU_1219516_0_0_1"/>
    <dbReference type="OrthoDB" id="3796057at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="227" mass="25471" checksum="823DDB1704C68F2B" modified="2014-04-16" version="1">MVLSDFDIAVSNLNIDQGDTIEDVMNVPFTTVVDAPVRDFATLYPHDQAESDEDEQINRYRRLIEEKLRVQVSAQELESKMAATKDITDRYAAQASPNTNKPSPPTPPPFHTRRASEPTLSPNTSSAITTPPKAPCNTPSSPTPNSLPPSKHRRNPDSRNIDFRRPRHKVEEEEEGEEEEEEEDLEQYRTMDLAPLEPIMQSSSAGDLITYGTPIKVRDVDIFRVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAA3</accession>
    <name>W6ZAA3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cobalamin-independent methionine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine synthase, vitamin-B12 independent isozyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_4059</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="14">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the vitamin-B12 independent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.14" evidence="4"/>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686533.1">
        <property type="nucleotide sequence ID" value="XM_007688343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAA3"/>
    <dbReference type="STRING" id="930090.W6ZAA3"/>
    <dbReference type="GeneID" id="19123903"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4059"/>
    <dbReference type="eggNOG" id="KOG2263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013175_0_0_1"/>
    <dbReference type="OrthoDB" id="1053771at2759"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019280">
        <property type="term" value="P:L-methionine biosynthetic process from L-homoserine via O-acetyl-L-homoserine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03312">
        <property type="entry name" value="CIMS_N_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000002">
        <property type="entry name" value="5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000003">
        <property type="entry name" value="5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00172">
        <property type="entry name" value="Meth_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013215">
        <property type="entry name" value="Cbl-indep_Met_Synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006276">
        <property type="entry name" value="Cobalamin-indep_Met_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01371">
        <property type="entry name" value="met_syn_B12ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003556">
        <property type="entry name" value="PRK05222.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30519">
        <property type="entry name" value="5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08267">
        <property type="entry name" value="Meth_synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000382">
        <property type="entry name" value="MeTrfase_B12_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 14" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE N-terminal" evidence="18">
        <location>
            <begin position="4"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="17">
        <location>
            <begin position="435"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="382"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="704"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="440"/>
            <end position="442"/>
        </location>
        <ligand>
            <name>L-homocysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="440"/>
            <end position="442"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="524"/>
            <end position="525"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="608"/>
        </location>
        <ligand>
            <name>L-homocysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="608"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="651"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="653"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="662"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="675"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="736"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF08267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC46915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="766" mass="86383" checksum="D00C5CD97E5DF964" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAC3</accession>
    <name>W6ZAC3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sec1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688982.1">
        <property type="nucleotide sequence ID" value="XM_007690792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAC3"/>
    <dbReference type="STRING" id="930090.W6ZAC3"/>
    <dbReference type="GeneID" id="19123298"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37665"/>
    <dbReference type="eggNOG" id="KOG1301">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016216_2_0_1"/>
    <dbReference type="OrthoDB" id="10251230at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035543">
        <property type="term" value="P:positive regulation of SNARE complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046578">
        <property type="term" value="P:regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="672" mass="74173" checksum="C5ACA8A2A7784121" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBB1</accession>
    <name>W6ZBB1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GDP-mannose transporter</fullName>
            <shortName evidence="7">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_90801</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cytoplasmic vesicle membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686277.1">
        <property type="nucleotide sequence ID" value="XM_007688087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBB1"/>
    <dbReference type="STRING" id="930090.W6ZBB1"/>
    <dbReference type="GeneID" id="19127756"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90801"/>
    <dbReference type="eggNOG" id="KOG1444">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025360_1_2_1"/>
    <dbReference type="OrthoDB" id="417037at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC47235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="384" mass="41926" checksum="1267648B0D2D38B3" modified="2014-04-16" version="1">MSDDKKSDDYRVDMPSGKEFRAPSPLPRASNSHRGGSTSITENPVAAILAYCGSSILMTVTNKYVLSGVDFNLPFFLLCVQSVVCVAAISICKSAGIITYRDFNSDEAKKWFPISLLLIGMIYTSTWALKFLSIPVYTIFKNLTIILIAYGEVLWFGGAVTPMALFSFGLMVFSSVIAAWADIQHALSSMGQSTSASTDAMSTLHAGYLWMMFNCLCTATYVLSMRKRIKLTNFKDFDTMYYNNLLTIPILLVASILVEDWSSANIQKNFPPDQRNTVITVMVVSGLSTVFISYTSAWAVRVTSSTTYSMVGALNKLPIALSGLIFFDAPVTFGSVSAIFVGFVSGLVYALAKIRQNSQPKTVLPTSNIPLSASSRSMQDSLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBQ4</accession>
    <name>W6ZBQ4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_97068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688598.1">
        <property type="nucleotide sequence ID" value="XM_007690408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBQ4"/>
    <dbReference type="GeneID" id="19128980"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97068"/>
    <dbReference type="HOGENOM" id="CLU_2612407_0_0_1"/>
    <dbReference type="OrthoDB" id="10339229at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="79" mass="8664" checksum="56E2C45E8B467482" modified="2014-04-16" version="1" fragment="single">INVKISSAGYGRSGVYEELLDRVCVQMRDAMSQGTLGLQCYGDIVGVHPGEHKRCAVNPSQSKEWHVCCDIVETAVDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBV2</accession>
    <name>W6ZBV2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_90493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBV2"/>
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    <dbReference type="OrthoDB" id="3757079at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889893" evidence="1">
        <location>
            <begin position="20"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="241" mass="26377" checksum="74ED192F9B6FCA8E" modified="2014-04-16" version="1">MHLSLLFIFFLNLLTTALTAPNSPALAPLEGLDTSTILYTPTPTLIHAFDAAITAKTNTHADNSNDNIANNANANLLLLPTQTITQTARVTQTSRPQDPEPIILYPFHLTLTSACSSSSSSYSANATLTNGNWTSRIINLTSSTRAIVDHHISGYPQTFSVGPFEAPRGELRFGYLNGEGGWRCEWGDGDKDKNEDGERSRGCGWCKGGEWRVAGCKRGWGIKEMDCEFIMGWRHQLKAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBV7</accession>
    <name>W6ZBV7_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_33332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684186.1">
        <property type="nucleotide sequence ID" value="XM_007685996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBV7"/>
    <dbReference type="GeneID" id="19122295"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33332"/>
    <dbReference type="eggNOG" id="ENOG502T61V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_187822_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="91" mass="10052" checksum="5F650B6C6E8D5D1E" modified="2014-04-16" version="1">MDALPDTTHSTSSRCSTPSTPDTPVSPASSTTSSYFSSSSSSEPQVPFQIIVTFDGKVREMLRIEREENSPIQAPKARKAPRPRYYARNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCD7</accession>
    <name>W6ZCD7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_5672</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688371.1">
        <property type="nucleotide sequence ID" value="XM_007690181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCD7"/>
    <dbReference type="GeneID" id="19124695"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5672"/>
    <dbReference type="eggNOG" id="ENOG502SKMD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_31_1_1"/>
    <dbReference type="OrthoDB" id="5329176at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="27"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="386" mass="43491" checksum="2F1046EDC4BA1695" modified="2014-04-16" version="1">MALSNLQPLAYAVAYITFMLGTISIFLRFYCRRYILHLWGWDDHFAVLILVFSIGQQVILHMFLYWGCGLHMTTLTTNQQLQILKWLFIEQVVYYSVHWVIKSAFLLFYLRLSTRRPFRIAIYIGGVINGTILIINTLMACFQCVPFDEILHPGTHPNAICINRLAMLIVPSVLNIFADFYILILPIYTVWHLQMTMGRKLRVIGVVAFGSSSVIIACFRLIPLFELFRSPDTSWVLGKMVIVAALEIQCAVIAVNLPSLKPLWTRMMGGSSSGSGPGNDSDGSNKKRYRISSRGHIATFGSEGRELRAGKWARKSHRGSVSRTDQGLTVTESEEELCRQGGISLRMSNQMSAGDAGTIKIQKDIHIQSSEGDLDKVITENYISRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCD9</accession>
    <name>W6ZCD9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_22848</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683959.1">
        <property type="nucleotide sequence ID" value="XM_007685769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCD9"/>
    <dbReference type="STRING" id="930090.W6ZCD9"/>
    <dbReference type="GeneID" id="19120335"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22848"/>
    <dbReference type="eggNOG" id="ENOG502S357">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020078_1_1_1"/>
    <dbReference type="OrthoDB" id="5571888at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14810">
        <property type="entry name" value="bZIP_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000031">
        <property type="entry name" value="BZIP transcription factor (MeaB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37616:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37616">
        <property type="entry name" value="BZIP TRANSCRIPTION FACTOR 60-LIKE"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="297"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="180"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC49472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="604" mass="66781" checksum="0EBFA971F22C7F91" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCT5</accession>
    <name>W6ZCT5_COCMI</name>
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        <recommendedName>
            <fullName evidence="16">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="16">1.6.2.2</ecNumber>
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    </protein>
    <gene>
        <name evidence="20" type="ORF">COCMIDRAFT_3240</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">May mediate the reduction of outer membrane cytochrome b5.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 16">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="16"/>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685644.1">
        <property type="nucleotide sequence ID" value="XM_007687454.1"/>
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    <dbReference type="AlphaFoldDB" id="W6ZCT5"/>
    <dbReference type="STRING" id="930090.W6ZCT5"/>
    <dbReference type="GeneID" id="19122098"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3240"/>
    <dbReference type="eggNOG" id="KOG0534">
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    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
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    </dbReference>
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        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
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        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
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        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 16" id="KW-0274">FAD</keyword>
    <keyword evidence="4 15 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="10 16" id="KW-0520">NAD</keyword>
    <keyword evidence="9 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="19">
        <location>
            <begin position="89"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EUC47760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="341" mass="37573" checksum="CE5E4106BCE79921" modified="2014-04-16" version="1">MFARQVFRPARTLHQQVRRYASEAPKSGGNNGVLYTGIGAAGLAGAYLFLRGGDSPSGQKGNAPPSKEANKIPSSTGGPAKKAFTGGDQGFLSLVLDKSEIVNHNTKKLTFKLPEEDMESGLPVASAVITKYKGPEMQKPVIRPYTPISDVDQKGTVDFIIKAYPNGPMSEHMHSMEPGQRLDIKGPIPKFQWSPNKFEHIALIAGGTGITPMWQTARAIFRNPEDKTKVTLVYGNVTEEDILLKREFEELENTYPQRFRAFYVLDNPPESWQGGKGYITKELLKTVLPEPKEGEKIKLFVCGPPGMYKAISGGKKSPSDQGELDGYLKELGYSKDQVYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD50</accession>
    <name>W6ZD50_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cenp-O kinetochore centromere component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_34642</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-O/MCM21 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685586.1">
        <property type="nucleotide sequence ID" value="XM_007687396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD50"/>
    <dbReference type="STRING" id="930090.W6ZD50"/>
    <dbReference type="GeneID" id="19122603"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34642"/>
    <dbReference type="eggNOG" id="ENOG502SCC4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042556_0_0_1"/>
    <dbReference type="OrthoDB" id="10050372at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031511">
        <property type="term" value="C:Mis6-Sim4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018464">
        <property type="entry name" value="CENP-O"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14582:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14582">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT MAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09496">
        <property type="entry name" value="CENP-O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33425" checksum="A5451B8FD474FB82" modified="2014-04-16" version="1">METVKQLDDEIGDLHARLATLQAQRANLSSVLVSQPHLAARLQNRNERSKSSDNAQQIIAQQSKRNLENVYRACAGVTAYRVKDPDPHAANDGNILGVSIDVSVAEKFIETYHVLLSVRDKGEKKLLSIHKHTIPPCIPLQQLAAKWLPGSGKDEEHDPEQDLVRFGRLLRKELVSWNMRIDAVRKLRKEAGLIKQRRDSEDLAIASTSNILNAFVSDDDASSDIDASEDGDGAARILDIEADAAVRQITITWSDRRTVAMSITKDGRIEKAVCRKRDGTRDAVLGKKAIGPIGSLMQRLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDA5</accession>
    <name>W6ZDA5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HPP transmembrane region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_34705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685676.1">
        <property type="nucleotide sequence ID" value="XM_007687486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDA5"/>
    <dbReference type="STRING" id="930090.W6ZDA5"/>
    <dbReference type="GeneID" id="19122621"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34705"/>
    <dbReference type="eggNOG" id="ENOG502S3SU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040397_0_2_1"/>
    <dbReference type="OrthoDB" id="2016548at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007065">
        <property type="entry name" value="HPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058581">
        <property type="entry name" value="TM_HPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04982">
        <property type="entry name" value="TM_HPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="HPP transmembrane region" evidence="3">
        <location>
            <begin position="38"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="253" mass="27840" checksum="B56B1C8CF605E7DC" modified="2014-04-16" version="1">MPIWDPLVPAERAIQRGLARLPPAVSHWFGYRPQNLPPSRTWLVCMWGFIGAFCGLSTILAIFGHTDYFRSRAVPPIIASFGASAILCYGAIDVPLAQPRSLVFGHFFSGLTGVIIATIFQFNLETEPFPRLQWLAASLATAIALVVMHLTKTTHPPAGATALLPCVDPHIWALRWYYLPVLLLSSTIVLVSAVLLMNVQRQYPKFWVAQIPPAPAAEKKEKSVVEKKANALNEGSEDGSARDTLQDMERGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDJ0</accession>
    <name>W6ZDJ0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_88800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685632.1">
        <property type="nucleotide sequence ID" value="XM_007687442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDJ0"/>
    <dbReference type="GeneID" id="19127346"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88800"/>
    <dbReference type="eggNOG" id="ENOG502QQVQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054785_2_1_1"/>
    <dbReference type="OrthoDB" id="536545at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15239">
        <property type="entry name" value="7tm_YRO2_fungal-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000160">
        <property type="entry name" value="Related to Opsin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018229">
        <property type="entry name" value="Rhodopsin_retinal_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043476">
        <property type="entry name" value="Yro2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF1">
        <property type="entry name" value="30 KDA HEAT SHOCK PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00950">
        <property type="entry name" value="BACTERIAL_OPSIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00327">
        <property type="entry name" value="BACTERIAL_OPSIN_RET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC47913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="306" mass="34503" checksum="CA49818E94E0F66D" modified="2014-04-16" version="1">MQLERRNDVFEHNGNTVNGRTADIGLTTHGSNFYFSICAVMTVAGFVFAAMSYRIERRNRIFHYITCGVVFVAAIAYFTMGANLGFTPIEVEFRRSDPVVRGTYRAIYYARYVDWFITTPLLLMDLLLTAGMPWPTILWVILVDEIMIVTGLIGALIQSIYKWPFFVFGCVALFYIVFQLTWEARIHSKTFGRDVERTFLMCGSLTAFLWILYPIAWGLSEGGNVIAPDSEAVFYGVLDFLAKPVFGALLLWGHRNIDPARLGLQIRDYNDDTMLQEKRAKDAAAHNGQNVVNPPHDGPAPATTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDK6</accession>
    <name>W6ZDK6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-hexosaminidase</fullName>
            <ecNumber evidence="7">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_88650</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="7"/>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685509.1">
        <property type="nucleotide sequence ID" value="XM_007687319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDK6"/>
    <dbReference type="STRING" id="930090.W6ZDK6"/>
    <dbReference type="GeneID" id="19127321"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88650"/>
    <dbReference type="eggNOG" id="KOG2499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007082_0_2_1"/>
    <dbReference type="OrthoDB" id="428480at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016231">
        <property type="term" value="F:beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030203">
        <property type="term" value="P:glycosaminoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06562">
        <property type="entry name" value="GH20_HexA_HexB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000063">
        <property type="entry name" value="Beta-hexosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF58">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001093">
        <property type="entry name" value="B-hxosamndse_ab_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886753" description="Beta-hexosaminidase" evidence="9">
        <location>
            <begin position="17"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase eukaryotic type N-terminal" evidence="11">
        <location>
            <begin position="17"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="10">
        <location>
            <begin position="223"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001093-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC47938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="617" mass="68028" checksum="3BFD20FC42944D80" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDK7</accession>
    <name>W6ZDK7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-splicing factor PRP46</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Pre-mRNA-processing protein 46</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_5269</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 8">Belongs to the WD repeat PRL1/PRL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687919.1">
        <property type="nucleotide sequence ID" value="XM_007689729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDK7"/>
    <dbReference type="STRING" id="930090.W6ZDK7"/>
    <dbReference type="GeneID" id="19124553"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5269"/>
    <dbReference type="eggNOG" id="KOG0285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_72_2_1"/>
    <dbReference type="OrthoDB" id="10256122at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000012">
        <property type="entry name" value="Putative pleiotropic regulator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045241">
        <property type="entry name" value="Prp46/PLRG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19923:SF0">
        <property type="entry name" value="PLEIOTROPIC REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19923">
        <property type="entry name" value="WD40 REPEAT PROTEINPRL1/PRL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="1 7 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="186"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="228"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="270"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="312"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="451"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00056150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU369036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC45554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="499" mass="54463" checksum="0C3EC57893CB6BDF" modified="2014-04-16" version="1">MADTAASRPPSTAEQLVRMSSKRTREIFAADFASSAALDHASNGSFSIHPTSPAPSTAADQAGVASRIRNEYEHVRELPPALAAKMASAASTAAERRKKIKAQNAEEKASDPKMQKMIEGVSEKADKARDAQSMQLAVRAGGKGAAPNAQGPTPNRDQTSSSLVRKDVVRQAKPEWHAPWKIKTVISGHMGWVRSVAMEPGNEWFATGAADRTIKLWDLASGRLKITLTGHISAVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYSLSLHPTVDVLCTGGRDGVVRVWDMRSRSNIHVLGGHKGTISSIQCQEAEPQVISGSMDSTIRLWDLVAGKTRTVLTHHKKSVRALATHPTEFTFASGSAQSAKQWLCPNGDFMQNFSPVNSIINTLSVNENNMMFAGSDNGEVSFYDWKTGHRFQHTESIAQPGSLEAEAGVMCSTFDASGLRLITGESDKSIKIWKQDENATEETHPLDWKPTLGRQKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZER0</accession>
    <name>W6ZER0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3669 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_1034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683123.1">
        <property type="nucleotide sequence ID" value="XM_007684933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZER0"/>
    <dbReference type="GeneID" id="19118294"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1034"/>
    <dbReference type="eggNOG" id="ENOG502SHT4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039531_2_1_1"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022137">
        <property type="entry name" value="Znf_prot_DUF3669"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40780">
        <property type="entry name" value="DUF3669 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40780:SF3">
        <property type="entry name" value="DUF3669 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12417">
        <property type="entry name" value="DUF3669"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3669" evidence="1">
        <location>
            <begin position="239"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="334" mass="38022" checksum="D5C6A95A8677D7A8" modified="2014-04-16" version="1">MQQTNNRYRCIGKGFCGSVWALEAATPQTAIKREDGGPGRSVTNDYNMHIKVVESAQQQQHHHYYYSLSTPLCIPQCHRLIQATDPWWHTSLPQFPPGYSACRALVSERVPKVPRSISNKLVDLFCAGNTPLSDFVKGNPDDDACLIRPYLGRRRRHRQDGVSQSQFQRFSLRNVPLHVDQMEVLGLDVKAYAGAMAEALALMHWGARIDANDVEFVLAPPRAGHASTFESEYLGVHCMWILDFDCCRPIQIDETGVEQASAAFYKNDPFYPRPGAGETADEELWMVFKQRFLESSHRIMGEERQDQWFLADMLVERIEEEGRSRRKDKEAGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZER9</accession>
    <name>W6ZER9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell wall mannoprotein PIR1-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_49634</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684959.1">
        <property type="nucleotide sequence ID" value="XM_007686769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZER9"/>
    <dbReference type="STRING" id="930090.W6ZER9"/>
    <dbReference type="GeneID" id="19124441"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_49634"/>
    <dbReference type="eggNOG" id="ENOG502RKR1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049782_0_0_1"/>
    <dbReference type="OrthoDB" id="5415592at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054508">
        <property type="entry name" value="PIR1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051153">
        <property type="entry name" value="Yeast_CWMannoprotein_PIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000420">
        <property type="entry name" value="Yeast_PIR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47254">
        <property type="entry name" value="CELL WALL MANNOPROTEIN CIS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47254:SF2">
        <property type="entry name" value="COVALENTLY-LINKED CELL WALL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00399">
        <property type="entry name" value="PIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22799">
        <property type="entry name" value="PIR1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886790" description="Cell wall mannoprotein PIR1-like C-terminal domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall mannoprotein PIR1-like C-terminal" evidence="5">
        <location>
            <begin position="65"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="149"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="306" mass="31134" checksum="3E0FBCEBE5662D6D" modified="2014-04-16" version="1" fragment="single">MKSFILTGLVAAATALPQAASGSECAASVDGTFTITTVKAPEADKKRALARRQLDGILTMTLQDGKLKDQAGRDGYIASNYQFQFDGPVQAGALDVDGFALCSNNSLSLKGSTLFYQCLSGDFYNLYSQSIGDQCLPINIVAVMVTDSESESKDPEVTQISDGQPQASEPAVTQISDGQPQASAPAPGSVAPPPPPVTQISDGQPQASAPGSLPPPPPPVTQISDGQPQASAPGSLPPPPVVTPEPEPEPETTPPAVTQISDGQPQITSPPGNHSITHTTPPLPDFTGAAASSVAGLGALVGGVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEX0</accession>
    <name>W6ZEX0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative glutathione-dependent formaldehyde-activating enzyme</fullName>
            <ecNumber evidence="5">4.4.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">S-(hydroxymethyl)glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_86974</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>S-(hydroxymethyl)glutathione = glutathione + formaldehyde</text>
            <dbReference type="Rhea" id="RHEA:22488"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="4.4.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (glutathione route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.22" evidence="5"/>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684985.1">
        <property type="nucleotide sequence ID" value="XM_007686795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEX0"/>
    <dbReference type="STRING" id="930090.W6ZEX0"/>
    <dbReference type="GeneID" id="19126964"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86974"/>
    <dbReference type="eggNOG" id="ENOG502SKH9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090716_0_0_1"/>
    <dbReference type="OrthoDB" id="3446116at2759"/>
    <dbReference type="UniPathway" id="UPA00562">
        <property type="reaction ID" value="UER00621"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051907">
        <property type="term" value="F:S-(hydroxymethyl)glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00723">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014185">
        <property type="entry name" value="Formald_GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02820">
        <property type="entry name" value="formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003829">
        <property type="entry name" value="PRK05417.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033318">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="21"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
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            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
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            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
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            <note>structural</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC48565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="192" mass="20841" checksum="3A2AECF16EFDF0DC" modified="2014-04-16" version="1">MASISIHPAIDNGIKKGNPNFPGGKLYCHCPSDKVEVTLSSNVAHNHACGCSKCWKPRGALFSVVGVLPKDNVSVTANGHKLHIIDESAAIQRNACKECGVHLFGRIVNDHPFKGLDFVHTELSNTSGWQEPQFAAFVSSIIEQGFNPAQMDAVREKFRSVGLQSYDVLSPQLMDLIATYTAQKNGKLPAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFG1</accession>
    <name>W6ZFG1_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_4619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46234.1"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFG1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_4619"/>
    <dbReference type="HOGENOM" id="CLU_1916716_0_0_1"/>
    <dbReference type="OrthoDB" id="10561363at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="132" mass="14379" checksum="E2F650A4D0E07059" modified="2014-04-16" version="1">MAQASSTLLATLAPTLGNPTWWNRTTSLRHAPRPGLGVSVPKPTSSPATQQMARRRHGPASSGPISLQVPAASLDWDWDWDWDWDLRKLIQQGHCVTLAGKGPMTAIIIPSLSLIRQSTDGTAFTNQRLTDN</sequence>
</entry>
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    <accession>W6ZFT1</accession>
    <name>W6ZFT1_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="4">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_103743</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="KI964064">
        <property type="protein sequence ID" value="EUC42366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691142.1">
        <property type="nucleotide sequence ID" value="XM_007692952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFT1"/>
    <dbReference type="STRING" id="930090.W6ZFT1"/>
    <dbReference type="GeneID" id="19118368"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103743"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008495_0_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000001">
        <property type="entry name" value="Aldehyde dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000012">
        <property type="entry name" value="Betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="756"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="493"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="507"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1116" mass="122654" checksum="79226BE0EB3D9036" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFT8</accession>
    <name>W6ZFT8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_33817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684724.1">
        <property type="nucleotide sequence ID" value="XM_007686534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFT8"/>
    <dbReference type="GeneID" id="19122411"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33817"/>
    <dbReference type="HOGENOM" id="CLU_2222767_0_0_1"/>
    <dbReference type="OrthoDB" id="10363818at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="106" mass="11338" checksum="0DCF5E18605ADDAB" modified="2014-04-16" version="1">MCGSMDSVLVDMEADGIVRTVFGCLMVMKASFVALANLSEEIGKLKVQSNIAKDNMSSYRTTYIVQSLGASSQGQKQCVRGVAKMLPTADITNRPSGADQDDSKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG34</accession>
    <name>W6ZG34_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chromatin associated protein KTI12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_2298</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the KTI12 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684588.1">
        <property type="nucleotide sequence ID" value="XM_007686398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG34"/>
    <dbReference type="STRING" id="930090.W6ZG34"/>
    <dbReference type="GeneID" id="19120355"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2298"/>
    <dbReference type="eggNOG" id="KOG3062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027147_2_0_1"/>
    <dbReference type="OrthoDB" id="9972657at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002734">
        <property type="entry name" value="Chromatin associated protein KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013641">
        <property type="entry name" value="KTI12/PSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12435">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08433">
        <property type="entry name" value="KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="33906" checksum="B5B7082238CB4E45" modified="2014-04-16" version="1">MPLILISGFPSAGKTTRARQLEQFFESTIASAPPDARTSRLKVHLINDQTLGVPRSVYRTARAEKDARAEEYSAVKRVLSRDDIVIADGLNYIKGFRYQLYCEAKALQTPSCVVKLHVGTPPDRCRENNKKLLADEETDGGYEEDVFENLIFRYEEPNGMTRWDSPLFIVVEEDETPPCDQIWEAMIGSDGKMKTVRPNMATVLKPATEQNYLYELDKTTSDILTQIMVYQKDHAGEGGGQIAVVDVEKPIELPATPMTLPQLQRIRRQFITLNRQHSFSKARIKEVFVDYLNAEFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG83</accession>
    <name>W6ZG83_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_81162</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682779.1">
        <property type="nucleotide sequence ID" value="XM_007684589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG83"/>
    <dbReference type="GeneID" id="19125815"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81162"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_43_5_1"/>
    <dbReference type="OrthoDB" id="5290825at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000474">
        <property type="entry name" value="Sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF13">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="132"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC50827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="632" mass="70482" checksum="2402C94C89CC605D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGF2</accession>
    <name>W6ZGF2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_35813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC46584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGF2"/>
    <dbReference type="STRING" id="930090.W6ZGF2"/>
    <dbReference type="GeneID" id="19122875"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35813"/>
    <dbReference type="eggNOG" id="KOG3041">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062658_0_0_1"/>
    <dbReference type="OrthoDB" id="10249920at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019693">
        <property type="term" value="P:ribose phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18888">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000016">
        <property type="entry name" value="ADP-sugar pyrophosphatase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF26">
        <property type="entry name" value="ADP-RIBOSE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="49"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="201" mass="22510" checksum="EF58AC39FF2DC2CB" modified="2014-04-16" version="1">MPQPPRILQIEDLPSNSAKWISFQKISWQDQTGKDRVWEAAARKTRGKSGVDAVAIVTIIRHPSRPPSTIIILQYRPPVDAVCVELPAGLVDEKESPSEASVRELHEETGYKGRLKFISPTIVSDPGMSTANMQLAVVEVELAEGDAEPEQALDDGEFIERVVVPVDELYERLIQYDKEGKRVDARLWHWAAGWHAAKSMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGL7</accession>
    <name>W6ZGL7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_102999</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964054">
        <property type="protein sequence ID" value="EUC42646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690851.1">
        <property type="nucleotide sequence ID" value="XM_007692661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGL7"/>
    <dbReference type="GeneID" id="19118201"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102999"/>
    <dbReference type="HOGENOM" id="CLU_2580211_0_0_1"/>
    <dbReference type="OrthoDB" id="10282140at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="87" mass="9420" checksum="BDBC71B25F8ECC94" modified="2014-04-16" version="1" fragment="single">PRASVMCIGTGAKGTWESLMAHGRGLAQGAPGGVVRETKPKLYDNPSPLCSSPPFVKGQWPLASSATRLGQRNRCDVHMCRWGAWKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGN3</accession>
    <name>W6ZGN3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_102892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964053">
        <property type="protein sequence ID" value="EUC42656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690809.1">
        <property type="nucleotide sequence ID" value="XM_007692619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGN3"/>
    <dbReference type="GeneID" id="19118179"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102892"/>
    <dbReference type="eggNOG" id="ENOG502RIFB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239940_0_0_1"/>
    <dbReference type="OrthoDB" id="3690919at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="223" mass="25109" checksum="D33EAD798AED1A22" modified="2014-04-16" version="1">MPPILTQSSPEPHESIDAILMLNTCNLPIITPCSATLNPHSFALPNLFHLLTCGHIVTIDDTDRRCAHNCHRTTATTSRPSEFPEPQYTNSADEITFTDTATNIYPDTLYCEVCTGIPFDRYYIMFPPPGPSLLRRCLALSRAIIAATMILPALAVDEILCPVLYVPGHVPHELRCGHRVWCMLERWCGVNCSDCREGRWKGLDAVVCEECVGRGERVYERYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGR5</accession>
    <name>W6ZGR5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_2151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684387.1">
        <property type="nucleotide sequence ID" value="XM_007686197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGR5"/>
    <dbReference type="GeneID" id="19120074"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2151"/>
    <dbReference type="eggNOG" id="ENOG502T1HW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047991_0_0_1"/>
    <dbReference type="OrthoDB" id="2520703at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056867">
        <property type="entry name" value="LRR_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24969">
        <property type="entry name" value="LRR_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Leucine-rich repeat" evidence="1">
        <location>
            <begin position="302"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="457" mass="51097" checksum="0CCEB28723252944" modified="2014-04-16" version="1">MTSERASLEGLPDELLLGILFHLRTIRSFGIYSPTFDESKEKARQQENRLRQLSLSNLCRTSRHLNRLTIPALYAAFTGSSTWPGIGSLRRFHQEITAPRGSLGGDSTYASHLQYVENRFSDYQGNDHFANLDDPSDLYMLKEYFSLLAGIINAAPNLQHISVANVETSDVSFLKHVLREDSAGTSGCTIVADHGLSRLQTLFVEMEMDEEWGLRKLREASIYSIYSALASLPSLSDFRVAGARMTPTIGPKVNVGQFRNLQRLEITHCLMEMSQMNIILSACEGLRHIVCHWEWLESDKTVDVLRPGLRKHSHTLETLSLDFRGVQWMSESYGNSGSIGSLRQFDHLHTLEITDTYFLTRFEYGPNGHYRAPTSKVAELLPLSLKMLNLFVDIADSPGFANSLDDSDSLWDLSAACNSSLINLSAITVEGIGPNDNIETLMSSFEQAGVLCEFIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHD9</accession>
    <name>W6ZHD9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_39011</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetes</taxon>
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                <person name="Schackwitz W."/>
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                <person name="Wang R."/>
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                <person name="Han J."/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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    </dbReference>
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        <source>
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        <source>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="956" mass="108722" checksum="7EBB492964D2634D" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44416.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50883.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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    <name>W6ZMP4_COCMI</name>
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        </recommendedName>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690432.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZMP4"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052765">
        <property type="entry name" value="PGM-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46192">
        <property type="entry name" value="BROAD-RANGE ACID PHOSPHATASE DET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="553"/>
        </location>
    </feature>
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        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
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        <location>
            <begin position="240"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
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        <location>
            <begin position="464"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="553" mass="62648" checksum="897F14A8A7FAD715" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNC0</accession>
    <name>W6ZNC0_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">Nucleoporin Nup54 alpha-helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_2252</name>
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        <lineage>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">ATCC 44560</strain>
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    </reference>
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        <subcellularLocation>
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            <location evidence="1">Nuclear pore complex</location>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF13874"/>
        </source>
    </evidence>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
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    <sequence length="418" mass="46865" checksum="C8C7AF4D819D7475" modified="2014-04-16" version="1">MSFSFGNIGGGEKKTGTLFGSTTAPAGGLFGQSQQQQQQPQQSSNTGGGLFGSAAPAQNNTTSLFSSTQPQQQQTTGSSLFGQPQQQQNAGASLFSQPQQPQQQAQPQQPNMSNSLFGASLQPAPILNSVQAQSIQQQREGLPQLRQSSAQPFAGSTMNGHREKSVVEQIRILNNKWDPENPECVFQFYFYNSVKPEEAPFYGPSQGEDERKWEEALSKKPSPGAIPVLARGFEQVGERIRQQAAAVTALRTRLHEINNSLSLLKDAHELTVASRITEAKRKHIVFTQRTLALATKVQILRNRGYVMDPQEEDLKKKLIELEKQTFDPVLGGRQEEIWARMSSVRERARILQEETEKLGRTMDKQQNGELLSEEDQKALEKLLKDYDRQLEHLKKWVDDTKEEYDEWEASKQARPAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNS7</accession>
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    </protein>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_96052"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF5">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY21"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="492"/>
            <end position="508"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC45216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="55314" checksum="022A80E354E23BF8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNT5</accession>
    <name>W6ZNT5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CST complex subunit Stn1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_33425</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Telomere</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EUC49164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNT5"/>
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    <dbReference type="eggNOG" id="ENOG502RY83">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="77828at2759"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="CST complex subunit Stn1 N-terminal" evidence="5">
        <location>
            <begin position="47"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="194"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="257" mass="29792" checksum="269142A55ED36E57" modified="2014-04-16" version="1">MSTLRPTRPYRLYPAYCFGASPTFNTWVKLTVADVHALRSEKDFEGQRIYFYHNHPIRYVRIVGVVVAIDDINLKYTVLTIDDGSGAIIELKIVREIPAEKNPVDTSSPTAIENVEVISRLGVFDVTVDKHPVDIGSVLKAKCTISEFRGIKQLELKRVALVTTTDEEARAWAETAAFKQQVLAKPWHISSSEHKKIKHDIKTEKNRQREYERRKAEYEVKKEEHRLAREAYYEQRERRLEVRRRKEEVVMNAGALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP49</accession>
    <name>W6ZP49_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_95654</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963985">
        <property type="protein sequence ID" value="EUC45381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007689908.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZP49"/>
    <dbReference type="GeneID" id="19128702"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95654"/>
    <dbReference type="eggNOG" id="KOG1795">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="1931567at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:pre-mRNA intronic binding"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="F:second spliceosomal transesterification activity"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd08056">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13838">
        <property type="entry name" value="RNase_H_like_Prp8_IV"/>
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    </dbReference>
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        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.230:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000002">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1570.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.40">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
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        <property type="entry name" value="MPN"/>
    </dbReference>
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        <property type="entry name" value="PRO8NT"/>
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        <property type="entry name" value="PROCT"/>
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        <property type="entry name" value="PRP8"/>
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        <property type="entry name" value="PRP8_domainIV"/>
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        <property type="entry name" value="Prp8_domainIV_fingers"/>
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        <property type="entry name" value="Prp8_domainIV_palm"/>
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        <property type="entry name" value="Prp8_U5-snRNA-bd"/>
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        <property type="entry name" value="Prp8_U5-snRNA-bd_sf"/>
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    <dbReference type="InterPro" id="IPR019580">
        <property type="entry name" value="Prp8_U6-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
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        <property type="entry name" value="RRM_spliceosomal_PrP8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08082">
        <property type="entry name" value="PRO8NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08083">
        <property type="entry name" value="PROCN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12134">
        <property type="entry name" value="PRP8_domainIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10598">
        <property type="entry name" value="RRM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10597">
        <property type="entry name" value="U5_2-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10596">
        <property type="entry name" value="U6-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="2096"/>
            <end position="2227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="2328" mass="270868" checksum="420AB2212BCFF124" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPF1</accession>
    <name>W6ZPF1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_26322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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        <location>
            <begin position="85"/>
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        </location>
    </feature>
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        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
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        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
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            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="237" mass="26365" checksum="CF21D51D6202FB73" modified="2014-04-16" version="1">MATVAVAPQTPSSPKVRIRSQSFDSPFLRISVTPVEESSFSKSTGALETLAGYDDMEESVAAGVFRSASTLPLLKTKMSDESMLSEALSASSSSVTTSPTSTESSMESDDEDDESIASDEEEEDDEEHREQHHHYQHQRPHPLTFAQSTTTNNTTSKDKDKDTTPSPLSPFLYQDTSCPMYSPWLVCAVLDMHDVHRLDWTSIADPIERVWGVRTSSADVLGILSDNGRVMRRRWWD</sequence>
</entry>
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        </recommendedName>
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            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_95059"/>
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    <dbReference type="OrthoDB" id="5310497at2759"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF1">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889976" description="Cell surface protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="27710" checksum="80AB95D477D01599" modified="2014-04-16" version="1">MRYSLVFTAALAASVQAHGVITQVQGANGVNMPGLSVADGTPRDSGNPLSGSEADTSIIRAKEMGGKASALGRTASGPVDAGAAIAKFMGTGAAGLGALLGGLGGNKRGLLDALTGGAGGAGGAGAGTKTPKGTTEQGVAAAAGSGASTGLPTTADDGTITMTFHQVNQDGAGPLTAQIDATSGGTDPAAFQDAQVTQNVPGIGIGGLSAASTTDFPVKVQMPAGMTCQGTAGGASNVCVVRMQNAALAGPFGGSAAFTQSAAAKKRAIEYNLRKRHMARGILGKPE</sequence>
</entry>
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        <recommendedName>
            <fullName evidence="3">PXA domain-containing protein</fullName>
        </recommendedName>
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    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_1684</name>
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    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ68"/>
    <dbReference type="STRING" id="930090.W6ZQ68"/>
    <dbReference type="GeneID" id="19119923"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1684"/>
    <dbReference type="eggNOG" id="ENOG502RM76">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007315_0_0_1"/>
    <dbReference type="OrthoDB" id="41200at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000065">
        <property type="entry name" value="PX domain protein (AFU_orthologue AFUA_2G07450)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF47">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 122 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PXA" evidence="3">
        <location>
            <begin position="184"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="379"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="437"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="717"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="442"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="731"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="754"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="773"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="805"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="825"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="878"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="890"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC49649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1087" mass="118498" checksum="E6064EE46CE60A6D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQP6</accession>
    <name>W6ZQP6_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">geranylgeranyl diphosphate synthase</fullName>
            <ecNumber evidence="3">2.5.1.29</ecNumber>
        </recommendedName>
    </protein>
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        <name evidence="10" type="ORF">COCMIDRAFT_22591</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="EMBL" id="EUC49814.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="374" mass="40880" checksum="CA4AF6E6ACCBD77E" modified="2014-04-16" version="1">MDPFQTVAREMKFLTGNIRQLLGSGHPTLDTVAKYYTQSEGKYVRPMLVLLMSRATALTPHRNIARGGIGSQSADISITNLSILADENPDTSPISSIRHDSAYTPEDSDILPSQRRLAEITELIHTASLLHDDVIDHSVSRRAAPSANIEFGNKMAVLAGDFLLGRASVALARLRDPEVTELLATVIANLVEGEFMQLKNTARDEKNPIWTEETVSYYLQKTYLKSASLISKSCRAAAILGGSTPEVVEAAYLYGKNLGLAFQLVDDMLDYTVSEAELGKPAGADLELGLATAPLLFAWKENKSLGKLVGRKFSEKGDVQQARQIVAQSSGLEQTRALAQEYVDKAIDAISFFPDSEAKTGLVEMCTKVMKRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQS8</accession>
    <name>W6ZQS8_COCMI</name>
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        <recommendedName>
            <fullName evidence="9">Nodulin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_93776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="eggNOG" id="ENOG502RWDV">
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 12-LIKE CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
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    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
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    </dbReference>
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        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="101"/>
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            <end position="132"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="318"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="217"/>
            <end position="266"/>
        </location>
    </feature>
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        <location>
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            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="55995" checksum="0B1B5612CA7551C8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZR44</accession>
    <name>W6ZR44_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">Ribosome biogenesis protein Alb1</fullName>
        </recommendedName>
    </protein>
    <gene>
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    </gene>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685345.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19122176"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32773"/>
    <dbReference type="eggNOG" id="ENOG502SC3P">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085138_1_0_1"/>
    <dbReference type="OrthoDB" id="5304887at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053278">
        <property type="entry name" value="Pre-60S_factor_ECM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022784">
        <property type="entry name" value="Ribosome_bgen_Alb1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28280">
        <property type="entry name" value="SHUTTLING PRE-60S FACTOR ECM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28280:SF1">
        <property type="entry name" value="SHUTTLING PRE-60S FACTOR ECM1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Alb1"/>
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        <location>
            <begin position="1"/>
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        </location>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
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            <begin position="24"/>
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        </location>
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        </location>
    </feature>
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            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="20187" checksum="CCC20F4D5271B0B1" modified="2014-04-16" version="1">MAKTAKVKKRQVTIHSRAARRATSPSLSLPLSAQPSTHTTRDSTSPSRPSTLNPHALAALDAGIQKRQKKTSNMTRAQRLRHQKGLERAEENMDKLANKRLKSAGKGRKVVERAKGWEDINGEGGKKGKKSVLGDGEEVDVKRGREWVGDEDMDEAGEVKDEGKEGDVAVVAQSVAVPEEVDEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZS81</accession>
    <name>W6ZS81_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_32458</name>
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    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_32458"/>
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    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887054" evidence="1">
        <location>
            <begin position="19"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="73" mass="8150" checksum="9202910F295607E0" modified="2014-04-16" version="1">MKAVSALALLFTLGAASAKYCPGSGMLCHYEGDYTCHKTCVKCNCDQEAWVDHQRRALVSRECNFIWSSKQNC</sequence>
</entry>
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    <accession>W6ZSI6</accession>
    <name>W6ZSI6_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_929</name>
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    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSI6"/>
    <dbReference type="STRING" id="930090.W6ZSI6"/>
    <dbReference type="GeneID" id="19128168"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_929"/>
    <dbReference type="eggNOG" id="KOG0266">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HET"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="286"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="713" mass="81275" checksum="D23EBDE903BF37B4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSJ0</accession>
    <name>W6ZSJ0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_4310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688625.1"/>
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    <dbReference type="STRING" id="930090.W6ZSJ0"/>
    <dbReference type="GeneID" id="19124199"/>
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    <dbReference type="eggNOG" id="KOG2309">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036235_0_3_1"/>
    <dbReference type="OrthoDB" id="10267824at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000006">
        <property type="entry name" value="60S ribosomal protein L8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="5">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="4">
        <location>
            <begin position="96"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="254" mass="27521" checksum="D8E4EFA524D32F5B" modified="2014-04-16" version="1">MGRVIRNQRKGRGSIFTANTRLNKNPAQFRTLDYAERNGYIRGVVKEIVHDSGRGAPLARVSFRNPYKFKHDTETFIANEGMYTGQFIYAGKNAALTIGNVLPLHSVPEGTVLTNVEDKNGDRGALGRTSGNYVTVIGHNPDEGKTRVKLPSGAKKVLPSSCRGMVGIVAGGGRTDKPLMKASRAKHKFAAKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRYATQGQKAGLIAARRTGLLRGTQKTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTG2</accession>
    <name>W6ZTG2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_32020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682697.1">
        <property type="nucleotide sequence ID" value="XM_007684507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTG2"/>
    <dbReference type="STRING" id="930090.W6ZTG2"/>
    <dbReference type="GeneID" id="19122008"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32020"/>
    <dbReference type="eggNOG" id="KOG0730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004471_6_3_1"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="517"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="732" mass="83412" checksum="032F4CB792236A7E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUN3</accession>
    <name>W6ZUN3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HORMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_89764</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAD2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685926.1">
        <property type="nucleotide sequence ID" value="XM_007687736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUN3"/>
    <dbReference type="STRING" id="930090.W6ZUN3"/>
    <dbReference type="GeneID" id="19127542"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89764"/>
    <dbReference type="eggNOG" id="KOG3186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050394_1_1_1"/>
    <dbReference type="OrthoDB" id="21254at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF10">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="3">
        <location>
            <begin position="6"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC47521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="283" mass="31648" checksum="4AEA92B301D1D1C3" modified="2014-04-16" version="1">MAPTYLETLNHFTTFLTAYTHTLLYLRTLYPRASFVQSRFHNASVYQSRHPLVCEWIADAIAAVREELLNGSVARIAIVVFSYEGDQESAKGSAKIMERYMFDVSSFPVVEKGDRNMEIEWQGTTPDVSDNEDEGGILKRGKTKELDTDVHVNLSEQFRAALIALTTRTSTLAPLPPNCSFNISMELKDEGDVDPPIGHPQPWIPVQPSLQKTGRTATIREELEEEEFESGRRTRKEGGDLGGAKVTPIRSVQSGVFRFETWIEEAKAKLQADGTKTSFPSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWY3</accession>
    <name>W6ZWY3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_2779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685108.1">
        <property type="nucleotide sequence ID" value="XM_007686918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWY3"/>
    <dbReference type="STRING" id="930090.W6ZWY3"/>
    <dbReference type="GeneID" id="19121184"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2779"/>
    <dbReference type="eggNOG" id="ENOG502SM5I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009374_0_0_1"/>
    <dbReference type="OrthoDB" id="5418088at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081">
        <property type="entry name" value="ZINC FINGER PROTEIN DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="809"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="801"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="851"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
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        <location>
            <begin position="368"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="488"/>
        </location>
    </feature>
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        <location>
            <begin position="514"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="563"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
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        <location>
            <begin position="607"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="638"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="782"/>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="851"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="896"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="930" mass="105633" checksum="2E37EA3FE2D028CA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWZ5</accession>
    <name>W6ZWZ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_2791</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685110.1">
        <property type="nucleotide sequence ID" value="XM_007686920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWZ5"/>
    <dbReference type="STRING" id="930090.W6ZWZ5"/>
    <dbReference type="GeneID" id="19121203"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2791"/>
    <dbReference type="eggNOG" id="KOG2655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017718_7_4_1"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Septin spn3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="16"/>
            <end position="291"/>
        </location>
    </feature>
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            <end position="317"/>
        </location>
    </feature>
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            <begin position="299"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="375" mass="42700" checksum="D5FD243112B71A77" modified="2014-04-16" version="1">MSSALNKTRRKKNVKKGIQFCLMVCGASGTGRTTFVNTLCGKQVLGHKEVDDPTTAHVEEGVKIKPITVELDEEGTRISLTIVDTPGFGDQIDNEASFSEIVGYLERQYDGILAEESRIKRNPRFRDDRVHVLLYFITPTGHGLRELDIELMKRLSPRCNVIPVIGKADSLTPAELAESKKLVMEDIEHYRIPVYNFPYDVEEDDEDTVEENAELRGLMPFAIVGSEDIVEVNGRRVRARQYPWGIVEVDNPRHSDFLAVRSALLHSHLADLKEITHDFLYENYRTEKLSKSVEGGAASNDSSMNPEDLASQSVRLKEEQLRREEEKLREIEVKVQREINEKRQELLARESQLKEIEARMHREQSGMAHDDADDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX63</accession>
    <name>W6ZX63_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">TFIID subunit TAF5 NTD2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_87420</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat TAF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685069.1">
        <property type="nucleotide sequence ID" value="XM_007686879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX63"/>
    <dbReference type="STRING" id="930090.W6ZX63"/>
    <dbReference type="GeneID" id="19127055"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87420"/>
    <dbReference type="eggNOG" id="KOG0263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005884_0_2_1"/>
    <dbReference type="OrthoDB" id="10266330at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08044">
        <property type="entry name" value="TAF5_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="10">
        <location>
            <begin position="92"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="382"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="437"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="491"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="533"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="575"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="625"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC48436.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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    <accession>W6ZZE0</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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    </feature>
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    </evidence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
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                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
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                <person name="Han J."/>
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                <person name="Lindquist E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
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</entry>
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    <accession>W6YLG7</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
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    </reference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF7">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004885981" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="34"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="117" mass="13160" checksum="4CD2EDD800812AC6" modified="2014-04-16" version="1">MNIRYISLVSVFALTTRAFWRPPCYSRLGVFRIDLIVSEGLPSQHAHTLHGAQNLDFSSSYDSLVQSKCTTCAVLEDMSAYWTPPLMFLHTNGTVEIVPQIGGMLMSVLKIKFKISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPV4</accession>
    <name>W6YPV4_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">STEEP1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_10355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STEEP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964336">
        <property type="protein sequence ID" value="EUC39553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693926.1">
        <property type="nucleotide sequence ID" value="XM_007695736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPV4"/>
    <dbReference type="STRING" id="930090.W6YPV4"/>
    <dbReference type="GeneID" id="19118331"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10355"/>
    <dbReference type="eggNOG" id="ENOG502SEMD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099097_2_0_1"/>
    <dbReference type="OrthoDB" id="418131at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029704">
        <property type="entry name" value="STEEP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057965">
        <property type="entry name" value="STEEP1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46355:SF1">
        <property type="entry name" value="STING ER EXIT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46355">
        <property type="entry name" value="UPF0428 PROTEIN CXORF56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25809">
        <property type="entry name" value="STEEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STEEP1" evidence="3">
        <location>
            <begin position="26"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC39553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="187" mass="20505" checksum="951459A4FB104C6E" modified="2014-04-16" version="1">MDIATTSRAYFAMPSPSPDEKISLQASNTVYTYHCLCSHLLLATTTPLPSLPTRRHSHDAAHIMPLPPPAPAALRKNSADSTASTHDHYGLLLSTRQERQAEIITSDSGFEKRYLQRCGRCDLVVGYQLDWQQFSVDRTGRREDYVFLLPGGFVKTSDMVANKMASASAASSSNPMGSTVNVTEVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQM1</accession>
    <name>W6YQM1_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_10060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964216">
        <property type="protein sequence ID" value="EUC39960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695330.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19117706"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10060"/>
    <dbReference type="eggNOG" id="KOG0717">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009539_2_1_1"/>
    <dbReference type="OrthoDB" id="5894at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051964">
        <property type="entry name" value="Chaperone_stress_response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054076">
        <property type="entry name" value="ZUO1-like_ZHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21884">
        <property type="entry name" value="ZUO1-like_ZHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="21"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="532"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="397"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="549"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC39960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="63758" checksum="539D4171EE2FE3DB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRT5</accession>
    <name>W6YRT5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_9896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964189">
        <property type="protein sequence ID" value="EUC40188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693304.1">
        <property type="nucleotide sequence ID" value="XM_007695114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRT5"/>
    <dbReference type="STRING" id="930090.W6YRT5"/>
    <dbReference type="GeneID" id="19129366"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9896"/>
    <dbReference type="HOGENOM" id="CLU_1758494_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="148" mass="16451" checksum="5F15B72B2D37CA87" modified="2014-04-16" version="1">MSAENSALTSPSSVSSTSRRHSIFSVSSTADRDKPLLAGAPTSYRFEIRPTPHAGRAVFAVQDMLKNALLWRLDDPTFGILWRYHNSYDWEKLLALALASDSTPYHNADDLSAFTRTYLHLLAILPPLLLPLVTAEIEDATIRIQVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS15</accession>
    <name>W6YS15_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_108887</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964167">
        <property type="protein sequence ID" value="EUC40420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693064.1">
        <property type="nucleotide sequence ID" value="XM_007694874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS15"/>
    <dbReference type="STRING" id="930090.W6YS15"/>
    <dbReference type="GeneID" id="19119327"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108887"/>
    <dbReference type="HOGENOM" id="CLU_000288_138_5_1"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF13">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="17408" checksum="00F83A68527B12A2" modified="2014-04-16" version="1">MKCYVYLSDVLTDSRDQLDPSFRSWEPAFRNSRWFTRGWTLQELLAPSSVEFFCSKGNRIGDKRSLAQEIHSITKIAIQALEGTPLSEFSVDERMSWAKIRQTKREEDRAYSLLGIFDIHMPLMYGKGASNALGRLQRKIERSLRLSSAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS30</accession>
    <name>W6YS30_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_109139</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964176">
        <property type="protein sequence ID" value="EUC40313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693164.1">
        <property type="nucleotide sequence ID" value="XM_007694974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS30"/>
    <dbReference type="STRING" id="930090.W6YS30"/>
    <dbReference type="GeneID" id="19119375"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109139"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_0_0_1"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006413">
        <property type="term" value="P:translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000136">
        <property type="entry name" value="DnaJ domain-containing protein Psi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000013">
        <property type="entry name" value="DnaJ subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="385" mass="40745" checksum="FC59EBC4F7596914" modified="2014-04-16" version="1">MVKETKLYEALGISESATQDEIKKAYRKAALKWHPDKNKDNPQASEKFKECSQAYEILSDPEKRKTYDQYGLEFLLRGGVPPEDTGGPGGNPFAGAGGGPGGFPFTSSGGMPGGTRTFHFSTGGGGNGFNFSNADDIFGEFMRNSAGGGGGGGGGDDFDFGGFGMGGMPGGMGGMPGMGGMGGMGGMGGGAGGKGGRFRGGRRAPEPEVTVVEKPLAVSLEELYNGTTKKLKIKRKTYDQSTGKQSTQDRILEVPIKKGLKPGSKIKFSDVGDQVEGGTQDLHFIVSEKPHAMFTREGDDIKHIIELDLKEALTGWRRTVQTIDGKQLSVGSGGPTGPNWTERYPNLGMPKSKKPAERGDFIVGVKIKFPTSLTSAQKEKLKEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS46</accession>
    <name>W6YS46_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_9674</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964164">
        <property type="protein sequence ID" value="EUC40450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693024.1">
        <property type="nucleotide sequence ID" value="XM_007694834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS46"/>
    <dbReference type="GeneID" id="19128907"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9674"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF158">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14490)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
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    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="519"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="49"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="563" mass="60075" checksum="B17BB7AFF3E96450" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSD3</accession>
    <name>W6YSD3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_108880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964167">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSD3"/>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_555465_0_0_1"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="423" mass="47514" checksum="531379C09210C5E3" modified="2014-04-16" version="1">MTPVSTTPPDWSALSSSQKWSTDPNLRARELGSKSAICADLHEPEYAMRDAEIRDALMHLVSLIQDFSRGFFSGEVRIPAPDGILPASFYEQMTPQTVKVVHCVASGGPAGQRGWHDLFLNEEKRQALVCGVIGNVLVEQVFENVCFGFGKEDKDAFSALERELKDEDGFTRHSRFSQTLHTLTHNATTLPPTSFTAHIQSILAALTTHLTPFLTLLHPTPLSTLPSLLPSLLTLTTRVALLSLHMRLDPHTLYRFTPSFKEDTYTPSRMHCTNVTQMQQSCPHNPSSVLTPAEQARRATLSKTELRRSKGDQALVQIIVFRGVVAFRKGGWEDGTSTGRNVVFEEKEFETEGFRERVLTRGWVYCRWGRGFARGMGEEMGRKVHGDAWREGGFVDFTKLEGVWDWLGEEEKEMRKGSEGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT24</accession>
    <name>W6YT24_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_103076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0357 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964055">
        <property type="protein sequence ID" value="EUC42607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692692.1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128832_1_0_1"/>
    <dbReference type="OrthoDB" id="447314at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018559">
        <property type="entry name" value="DUF2015"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023:SF1">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09435">
        <property type="entry name" value="DUF2015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="123" mass="13994" checksum="114AA647747689AC" modified="2014-04-16" version="1">MEYLFYSVCFFVLAVATAAYFTRHRWIHVLPIPEPIYARLPTSFRDDIEAGLSSSAFDLSGNVESGDSRQGLDDAGKKEVMSIMKRQGVDFDEARRIYMQDRFKKNNIGADGIPRDPKFVSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTA3</accession>
    <name>W6YTA3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_9354</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964136">
        <property type="protein sequence ID" value="EUC40835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692639.1">
        <property type="nucleotide sequence ID" value="XM_007694449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTA3"/>
    <dbReference type="STRING" id="930090.W6YTA3"/>
    <dbReference type="GeneID" id="19128286"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9354"/>
    <dbReference type="eggNOG" id="KOG3801">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120076_0_0_1"/>
    <dbReference type="OrthoDB" id="275715at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990221">
        <property type="term" value="C:L-cysteine desulfurase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20264">
        <property type="entry name" value="Complex1_LYR_LYRM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045297">
        <property type="entry name" value="Complex1_LYR_LYRM4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051522">
        <property type="entry name" value="ISC_assembly_LYR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13166:SF7">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13166">
        <property type="entry name" value="PROTEIN C6ORF149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="3">
        <location>
            <begin position="14"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="113" mass="13305" checksum="955DF4A5513B8920" modified="2014-04-16" version="1">MSLAQATKGDVAYQVRSLYRSLLRQSNQFAAYNFREYAKRRTRDAFRDNKDVKDERVIQEMVQKGLSELQMLKRQTVISQFYQIDRLVVEGGKEGKQKGNRNDIVRVKDQGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUE8</accession>
    <name>W6YUE8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thiamine thiazole synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Thiazole biosynthetic enzyme</fullName>
            <ecNumber evidence="6">2.4.2.60</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_30031</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[ADP-thiazole synthase]-L-cysteine + glycine + NAD(+) = [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:55708"/>
            <dbReference type="Rhea" id="RHEA-COMP:14264"/>
            <dbReference type="Rhea" id="RHEA-COMP:14265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:90873"/>
            <dbReference type="ChEBI" id="CHEBI:139151"/>
            <dbReference type="EC" id="2.4.2.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homooctamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">During the catalytic reaction, a sulfide is transferred from Cys-225 to a reaction intermediate, generating a dehydroalanine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the THI4 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.60" evidence="6"/>
    <dbReference type="EMBL" id="KI964117">
        <property type="protein sequence ID" value="EUC41158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692325.1">
        <property type="nucleotide sequence ID" value="XM_007694135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUE8"/>
    <dbReference type="STRING" id="930090.W6YUE8"/>
    <dbReference type="GeneID" id="19121607"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30031"/>
    <dbReference type="eggNOG" id="KOG2960">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053727_0_0_1"/>
    <dbReference type="OrthoDB" id="410463at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160205">
        <property type="term" value="F:cysteine-dependent adenosine diphosphate thiazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052837">
        <property type="term" value="P:thiazole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03158">
        <property type="entry name" value="THI4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027495">
        <property type="entry name" value="Sti35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002922">
        <property type="entry name" value="Thi4_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00292">
        <property type="entry name" value="sulfide-dependent adenosine diphosphate thiazole synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422:SF3">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01946">
        <property type="entry name" value="Thi4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
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        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="304"/>
            <end position="306"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="2,3-didehydroalanine (Cys)" evidence="6">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="337" mass="35999" checksum="83A76A7971068BD3" modified="2014-04-16" version="1">MSPPAAMYERPTAVDGNGIAKDLSLKKDLAVKDASVVAGGQAKTVADLENNWDKFTFAPIRESQVSRAMTRRYFNDLDTYAESDVVIVGAGSCGLSTAFTLATKRPDLKIAIVEAGVAPGGGAWLGGQLFSAMVMRKPAELFLNELGVPYEDEGDFVVVKHAALFTSTLLSKVLQFPNVKLFNATTVEDLITRPAPTANDPNAVRIAGVVTNWTLVSMHHDDQSCMDPNTINAPLVISTTGHDGPFGAFSVKRLVSMQQLEKLGGMRGLDMRTAEDAIVKRTREIVPGLIVGGMELSEVDGANRMGPTFGAMALSGVKAAEEAISVWEARQAQNLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUM8</accession>
    <name>W6YUM8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_106653</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964112">
        <property type="protein sequence ID" value="EUC41253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692229.1">
        <property type="nucleotide sequence ID" value="XM_007694039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUM8"/>
    <dbReference type="GeneID" id="19118896"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106653"/>
    <dbReference type="eggNOG" id="ENOG502T4GX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1230135_0_0_1"/>
    <dbReference type="OrthoDB" id="3768069at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886133" evidence="2">
        <location>
            <begin position="18"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="199" mass="21837" checksum="E386D49EA5C52E15" modified="2014-04-16" version="1">MFRTITTLTLLLTSSLAAPTTNTPTHHPSDLECRCLTFSTSAAPTHCPYQELLALDWDAALSLATANDLKLQFASDATIAKVLAIPTPVDPSILDAIQQGKTLPLDPAEQVRSENRIICGFEDDVERVERCEDDGVGMMGAPEVHYVGTVVGLFMLFFVAYLVAEYLWTVCFARTRGIRLEGEEKALTVECDGLMPDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVA0</accession>
    <name>W6YVA0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_106100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964101">
        <property type="protein sequence ID" value="EUC41470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692013.1">
        <property type="nucleotide sequence ID" value="XM_007693823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVA0"/>
    <dbReference type="GeneID" id="19118800"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106100"/>
    <dbReference type="eggNOG" id="ENOG502T0RA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_154032_0_0_1"/>
    <dbReference type="OrthoDB" id="2818448at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889440" description="Extracellular membrane protein CFEM domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9150" checksum="D83CFB5C77B2D5B6" modified="2014-04-16" version="1">MVRLSIFAVIFAAVTSVAADGFCQCLFPDGSHCCVVEYGIRKACVELCKDNGNSDKMCNAGGKYSDVSTWNGMWRRSCKYSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVK6</accession>
    <name>W6YVK6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_65699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964344">
        <property type="protein sequence ID" value="EUC39539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693941.1">
        <property type="nucleotide sequence ID" value="XM_007695751.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVK6"/>
    <dbReference type="STRING" id="930090.W6YVK6"/>
    <dbReference type="GeneID" id="19125003"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_65699"/>
    <dbReference type="eggNOG" id="ENOG502SMAU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054243_0_0_1"/>
    <dbReference type="OrthoDB" id="5275938at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="11"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="316" mass="35276" checksum="06F06EC9470BAA39" modified="2014-04-16" version="1" fragment="single">NANSLVLAPEGDVILVVGEKRFRIHADSLFLKRHSTVFAALFGPNFREGQDLNTSSPKEIPLPDDDPYAMTAICATMYHDFGHIPRSPTTDRVLSIIRHADKYDCYDVLTLPSQVYGWLKSDHLTLGNDLANILAVSYLVRDQEAFKNASKSLISKYGGSFADLADGVICDVLPWKTFCKLEELRTRIQTLAISIALDASVAKSSAFGYNNHSGCSQVAERIRGNFSNDLLVEVRQKQNQKHGGRLNFKLPHPPATRQSEIEPLLEKLQELAKACKKCNENVESSQLNTFCLSLAGNELRQVAMLPEWYWGSNLTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVR1</accession>
    <name>W6YVR1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_29616</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964093">
        <property type="protein sequence ID" value="EUC41635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691844.1">
        <property type="nucleotide sequence ID" value="XM_007693654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVR1"/>
    <dbReference type="STRING" id="930090.W6YVR1"/>
    <dbReference type="GeneID" id="19121542"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29616"/>
    <dbReference type="eggNOG" id="KOG2518">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008978_2_3_1"/>
    <dbReference type="OrthoDB" id="26491at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09908">
        <property type="entry name" value="H3TH_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09857">
        <property type="entry name" value="PIN_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000011">
        <property type="entry name" value="exonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000002">
        <property type="entry name" value="Exonuclease 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037315">
        <property type="entry name" value="EXO1_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044752">
        <property type="entry name" value="PIN-like_EXO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF65">
        <property type="entry name" value="DNA DAMAGE-INDUCIBLE PROTEIN DIN7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="16">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="15">
        <location>
            <begin position="138"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="336"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="413"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="542"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="620"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="672"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="507"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="565"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="623"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC41635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="724" mass="79398" checksum="7D6A9F99EAC17E5F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVR3</accession>
    <name>W6YVR3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_41896</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">ATCC 44560</strain>
        </source>
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    </feature>
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    </feature>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="369" mass="40503" checksum="1E6A9157079F8672" modified="2014-04-16" version="1">MCVHTLQGHDDAVVSVAFSHDSARLASASRDSTVKIWNASSGACLQTLEDHHCNVTSVVFSYDSTQLASASMDSTVKIWDMSSGTCRHTLEGYSGGVNSIAFSHDSTELALALDYSTIEIWSMRTREHLHTLRGHCIDVTSVAFSHDSHRIASGSSDCTVKIWNTSSSEHLSSPWDHKLGVSSVDFSHDLTRLASGSWDRTVKIWNAISGEHLHTFTAHSEGVSSVAFSHGSNWLASASLDKTIKIWDTSSWECRKNLNHGWDVTSVAFSHDSIWLASASQNGTVKIWDVSSGTCLQTLKGHSNWVTSVAFSRDSAQLASASTDKTVRIWKATDGACLKKLNWAPSRFLFSRLLAQILQHQNYRTKVSV</sequence>
</entry>
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    <name>W6YW80_COCMI</name>
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        </submittedName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="224"/>
            <end position="277"/>
        </location>
    </feature>
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        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC41810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="277" mass="30485" checksum="45B3E6ECE9FDD4CF" modified="2014-04-16" version="1">MLLRLGSLSFELSMWSPIYAVAPFVLLSISIPLAFFALVTTSIAITLLSLRALAVYFRLAIAIVGVWLSPSPPSKYRPSRRSRPVPTSARHSPKSMHQRSRRTSIAGTASTQGPGAYSAQPPNFLQRKNNSLTALIGTSELTRDFEGVGGWRVAGDDDEEALWMGINSRLELPAETPTRRRRLSHTGTASPGQRLSVGSEILRMSPVQSRSRTPVRFVHDDEYGYFPQQPIPNNTRFSHSPDIAHERKRRKSVSASSTSSTTSTGLTIATKHPGEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWV8</accession>
    <name>W6YWV8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase III subunit RPC3</fullName>
            <shortName evidence="8">RNA polymerase III subunit C3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_99670</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
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        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC43872.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691428.1"/>
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    <dbReference type="STRING" id="930090.W6YWV8"/>
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    <dbReference type="eggNOG" id="KOG2587">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023294_0_0_1"/>
    <dbReference type="OrthoDB" id="272392at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055207">
        <property type="entry name" value="POLR3C_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013197">
        <property type="entry name" value="RNA_pol_III_RPC82-rel_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008806">
        <property type="entry name" value="RNA_pol_III_Rpc82_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039748">
        <property type="entry name" value="RPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12949:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12949">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08221">
        <property type="entry name" value="HTH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05645">
        <property type="entry name" value="RNA_pol_Rpc82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22536">
        <property type="entry name" value="WHD_POLR3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase III subunit RPC82-related helix-turn-helix" evidence="11">
        <location>
            <begin position="14"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase III Rpc82 C -terminal" evidence="10">
        <location>
            <begin position="235"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase III subunit RPC3 winged-helix" evidence="12">
        <location>
            <begin position="510"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="132"/>
            <end position="224"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC43872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="679" mass="76895" checksum="46D2F8456903F2E9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXS2</accession>
    <name>W6YXS2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_103736</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964064">
        <property type="protein sequence ID" value="EUC42365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691141.1">
        <property type="nucleotide sequence ID" value="XM_007692951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXS2"/>
    <dbReference type="GeneID" id="19118367"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103736"/>
    <dbReference type="eggNOG" id="ENOG502SIX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072640_0_0_1"/>
    <dbReference type="OrthoDB" id="5175824at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="3">
        <location>
            <begin position="23"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="232"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC42365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="261" mass="29908" checksum="A858959533E6D75E" modified="2014-04-16" version="1">MTSEIEQLKAMVEKLQSQVTRLSEDIRKLQYTYGYYLDKCLYKEVTDLFSDHPDSCVEFLGGRYDGKAGVRRLYVGRFAKMFVAGRNGPVHGFLLDHPQLQGIVDVNAQGTRAKGRFRSMMSAGTHESIKDTHPRGLVQWWEGGIYENEYIKEDGVWKIFRLKYFPFWHAPFDKGWSYTKPNHVPFPKTTFPEDPIGPDVLCENPMLWPDTRVVPFHYTHPITGEQVADDDLRAPHYGKDPSTSTPPLVLSKPRSEVNGVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY09</accession>
    <name>W6YY09_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_103396</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NOSIP family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964060">
        <property type="protein sequence ID" value="EUC42463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691014.1">
        <property type="nucleotide sequence ID" value="XM_007692824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY09"/>
    <dbReference type="GeneID" id="19118292"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103396"/>
    <dbReference type="eggNOG" id="KOG3039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053742_1_1_1"/>
    <dbReference type="OrthoDB" id="116827at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:001463">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016818">
        <property type="entry name" value="NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063">
        <property type="entry name" value="ENOS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063:SF10">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023577">
        <property type="entry name" value="ENOS_interacting"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="247"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="180"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="313"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="59"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR023577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="358" mass="40022" checksum="5A2E1D9F5ACCB28F" modified="2014-04-16" version="1">MPPPKTVFTSYERNSLKDRWGSQSTRLTRDSFLPFGSCQLCLLPSVDPVCCSQGDLFCRECALTNLLAQKNEMKRLEKLNERQKLEEEENKLREEEEARLRAVEEFELVQQGLSVKAGSSAKMVGREGGKIVVEEEQDPKAAGHGRGTKRKFEIDEEELKRIANEEQRKAKRNLDEERKAAKGHLPSFWVPGETPDQHHKTAEKAKNTPICPSSSPDQPHSLSLKGLTRVHFHEEKSTETGKPVRTCPSCQKALSNSTKAMLAIPCGHVLCKPCVDKFLKPEHRHHRDAHDDAPEPDSIHCYVCDADLSAVPDTKEGKKKKKKEQAPKPGLVEIRSEGTGFASGGKAMVKREGVAFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY15</accession>
    <name>W6YY15_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_41229</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964165">
        <property type="protein sequence ID" value="EUC40444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693038.1">
        <property type="nucleotide sequence ID" value="XM_007694848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY15"/>
    <dbReference type="GeneID" id="19124020"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41229"/>
    <dbReference type="HOGENOM" id="CLU_028200_4_0_1"/>
    <dbReference type="OrthoDB" id="2496787at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964147">
        <property type="protein sequence ID" value="EUC40674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007694626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYS3"/>
    <dbReference type="STRING" id="930090.W6YYS3"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_108184"/>
    <dbReference type="eggNOG" id="ENOG502SN70">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044860_2_0_1"/>
    <dbReference type="OrthoDB" id="3485856at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="362" mass="41210" checksum="0E8F7BDC498D5042" modified="2014-04-16" version="1">MNYQNVTPPPRFTDDPLTPPSTAKKPFAEAHRVIALFKQIHAGTDAERDARTEFQLADGEYDQIESTLQQDDVLSGYVDEKIRYDYDEDKRKLVVRMPTEIHERFIDKVEDDIRSQLKTIQNGSGKKAEFAQKVHPARSTHIRLGDSMSSKSKYEPDASFRHKHAQYPGVIVEVAYSQKKPCLGRLAENYILDSDASIRAVVCVHIEYGNKESRKATLSVWRPKLFNTDDGLELQAVEEVADVAFRDEEGNPVDYPGLQLRLSEFAYEGLAQKEMGDEDTLVHISGTKLCEYLNAADGKEEKALGKHVFAKEVKKRKRSETPPEEIRAGDEAIYAREEERAAKRTDRDMDYQDRSSTKSFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYY2</accession>
    <name>W6YYY2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964049">
        <property type="protein sequence ID" value="EUC42783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690688.1">
        <property type="nucleotide sequence ID" value="XM_007692498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYY2"/>
    <dbReference type="STRING" id="930090.W6YYY2"/>
    <dbReference type="GeneID" id="19121344"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28638"/>
    <dbReference type="eggNOG" id="ENOG502S00E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107695_0_0_1"/>
    <dbReference type="OrthoDB" id="9980836at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="225" mass="25416" checksum="3419526BE24C03BB" modified="2014-04-16" version="1">MSANIETTSLTPEKLVSKLLSTIEESIIPLTQQGVSSGSKLFGAAILSRKDLTPYTLATNNERVSPLLHGEINCIQQFCMVDFPDPATRPHPAKDCIFLATHEPCSLCLSGITWAGFNEFYYLFTYEDSRDLFGIPYDIDILQEVFRVRGEGESEEQAQRKQLYNRKNKFFTAKSFADVVGEVSDESERERLLKEIMRVKGLYNSLSETYQEGKKAGTESSSIWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZN1</accession>
    <name>W6YZN1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_30160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964126">
        <property type="protein sequence ID" value="EUC40994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692486.1">
        <property type="nucleotide sequence ID" value="XM_007694296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZN1"/>
    <dbReference type="GeneID" id="19121627"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30160"/>
    <dbReference type="HOGENOM" id="CLU_625542_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="438" mass="47771" checksum="60B6E17518D3C3B1" modified="2014-04-16" version="1">MSLAPILDDSDCRRCDFVDVGGVRVYRARVCVRVCTKRFICNLPSTSSTSTSSSGGGGVEERAWSVRVSRQSPQLASLPLLMLAVRLLFPPLLRLVRQYAVAAGIMQYGTIFFPYPEQMQGPWCAAEKPRALPVDTEAVAETTSNCSNVHHDGSHGRPREPTSQSSNRQPGNPSNQSAISQSDESDTPTLDLEEPLDGRGCRSVCTYMHTRRKHVSSRGPARQIHGRSSSLARLLPIISPTLARLVCLQSPLAGACEPGTHDCTTSRDVWWLHITATPLGRQRGGVSMVPGPSAVLHTLTLDTQLYATKYVGSKEVKYHGCLCSITYMAGSSPAIHVKCDVRHSVPSAIAQPDLHCLAGPARSAWSQNGNVNMVCRSKSVMHAAERPPKGSFRPPSRRPKSRYQTLDAWLRLDAGVEPIFRHEAGADAHYVLRENDGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZU2</accession>
    <name>W6YZU2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690362.1">
        <property type="nucleotide sequence ID" value="XM_007692172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZU2"/>
    <dbReference type="GeneID" id="19123579"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38916"/>
    <dbReference type="eggNOG" id="ENOG502T69V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1107455_0_0_1"/>
    <dbReference type="OrthoDB" id="3685058at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="281" mass="30404" checksum="98E909440B90AF3D" modified="2014-04-16" version="1">MIEVFKDMKHGKSSSYDSLALERTASQILHRMEDKDSEYALESIRTRVLANARAIYGPNRCLDVISFAPTSSRRVGACIVEHNPSSKSYIHCCSAKETSRLAALEHLLVITEDLLQRLMDVEGITSSGWLPATPQSQHAAIYGSACGSTVGGTGSGSMASSVQTSRRGSAQPQDLFLDHGHGSPQSTQPPQQLQHPHPHPVPSQLPFVNDFNAPSSPHHIQKPRLPRGGSETSFPTSTPKPMAQTIARTNSDVIQHPKPVPVGQLAVPGRGRVQWNLGSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0N3</accession>
    <name>W6Z0N3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_101401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690280.1">
        <property type="nucleotide sequence ID" value="XM_007692090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0N3"/>
    <dbReference type="GeneID" id="19117867"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101401"/>
    <dbReference type="HOGENOM" id="CLU_1481730_0_0_1"/>
    <dbReference type="OrthoDB" id="3694476at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="177" mass="19901" checksum="7F6CD9370D84D27B" modified="2014-04-16" version="1">MSFPTPASTATNSASPHTQQPQQLLQSQHPQQPKQEDSPRFKPLASITEVPSLACTSTRPFTIAELEKTPPFFFTFPTTVKLKNHDSIQVTNATHMNELLFWYRFHSGEYSDAELKGLASKLDVGRATMRREEYDGGWVVDASLREGSGKEGKGEEEGRREEEVEMEVEIKEQAEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0T5</accession>
    <name>W6Z0T5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ArsA/GET3 Anion-transporting ATPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_100490</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the arsA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964025">
        <property type="protein sequence ID" value="EUC43570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689924.1">
        <property type="nucleotide sequence ID" value="XM_007691734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0T5"/>
    <dbReference type="STRING" id="930090.W6Z0T5"/>
    <dbReference type="GeneID" id="19117684"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100490"/>
    <dbReference type="eggNOG" id="KOG2825">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040761_0_0_1"/>
    <dbReference type="OrthoDB" id="1770at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043529">
        <property type="term" value="C:GET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071816">
        <property type="term" value="P:tail-anchored membrane protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02035">
        <property type="entry name" value="ArsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000235">
        <property type="entry name" value="ATPase ASNA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03112">
        <property type="entry name" value="Asna1_Get3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="ArsA/GET3_ATPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027542">
        <property type="entry name" value="ATPase_ArsA/GET3_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803:SF3">
        <property type="entry name" value="ATPASE GET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ArsA/GET3 Anion-transporting ATPase-like" evidence="10">
        <location>
            <begin position="25"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC43570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="339" mass="37665" checksum="D4EA85153AC1E5F5" modified="2014-04-16" version="1">MASTALIDADMAPTLQSILDQKTLRWIFVGGKGGVGKTTTSCSLAIQLAKHRRSVLLISTDPAHNLSDAFNQKFGKDARLINGFDNLSAMEIDPNGSIQDLLASGAEEGQDPMAGLGGMGSMMQDLAFSIPGVDEAMSFAEVLKQVKSMSYEVIIFDTAPTGHTLRFLQFPTVMEKALSKVSQLSRQFGPMLNSFLGSSGRLPNGQNMDELIQKMEALRETIGEVNGQFKDADLTTFVCVCIPEFLSLYETERMIQELNSYEIDTHSIVVNQLLFPKQSNPCEQCNARRKMQKKYLDQIEELYDEFNVVKMPLLVEEVRGKEKLEKFSEMLVNPFVPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z127</accession>
    <name>W6Z127_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_36841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963984">
        <property type="protein sequence ID" value="EUC45462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688034.1">
        <property type="nucleotide sequence ID" value="XM_007689844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z127"/>
    <dbReference type="GeneID" id="19123121"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36841"/>
    <dbReference type="HOGENOM" id="CLU_3068304_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="53" mass="5818" checksum="B577F22B2E8BA9D5" modified="2014-04-16" version="1">MSSDAHSCYGEGSRAMGEVLIAWVENRSLPAGLLPPLHGAELHFESVSRFQLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1D7</accession>
    <name>W6Z1D7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_106113</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964101">
        <property type="protein sequence ID" value="EUC41464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692007.1">
        <property type="nucleotide sequence ID" value="XM_007693817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1D7"/>
    <dbReference type="GeneID" id="19118806"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106113"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_4_1"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="529"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="557"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC41464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="65909" checksum="CB5F1000BAF31C84" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1U7</accession>
    <name>W6Z1U7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_72491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963979">
        <property type="protein sequence ID" value="EUC45707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687795.1">
        <property type="nucleotide sequence ID" value="XM_007689605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1U7"/>
    <dbReference type="GeneID" id="19125228"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_72491"/>
    <dbReference type="eggNOG" id="ENOG502RNBJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2365205_0_0_1"/>
    <dbReference type="OrthoDB" id="5421503at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="91" mass="9883" checksum="BA937DA61F5383F8" modified="2014-04-16" version="1" fragment="single">LSNTPRAAHQISLFLHTAVDSGLDSGVGISIIQSTAPGMGLSFTLPTEEQAHGIERSQARAKNIKTPERAHMFALILAMWLARSTIRRKCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1Y5</accession>
    <name>W6Z1Y5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="15">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_5099</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14 15">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="15"/>
    <dbReference type="EMBL" id="KI963978">
        <property type="protein sequence ID" value="EUC45767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687714.1">
        <property type="nucleotide sequence ID" value="XM_007689524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1Y5"/>
    <dbReference type="STRING" id="930090.W6Z1Y5"/>
    <dbReference type="GeneID" id="19124497"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5099"/>
    <dbReference type="eggNOG" id="KOG0202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_3_2_1"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02083">
        <property type="entry name" value="P-type_ATPase_SERCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000005">
        <property type="entry name" value="Calcium-transporting ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000021">
        <property type="entry name" value="calcium-transporting ATPase, endoplasmic reticulum-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000027">
        <property type="entry name" value="Calcium-transporting ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000037">
        <property type="entry name" value="Calcium-transporting ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000014">
        <property type="entry name" value="Calcium-transporting ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005782">
        <property type="entry name" value="P-type_ATPase_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01116">
        <property type="entry name" value="ATPase-IIA1_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 15" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12 15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="754"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="787"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="827"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="926"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="3"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC45767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1006" mass="108986" checksum="06CEFADC46C4F149" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z228</accession>
    <name>W6Z228_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_94569</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Also a component of the nuclear pore complex.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
            <location evidence="1 11">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the dynein light chain family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC45807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687688.1">
        <property type="nucleotide sequence ID" value="XM_007689498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z228"/>
    <dbReference type="STRING" id="930090.W6Z228"/>
    <dbReference type="GeneID" id="19128474"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94569"/>
    <dbReference type="eggNOG" id="KOG3430">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070944_4_2_1"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040001">
        <property type="term" value="P:establishment of mitotic spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051292">
        <property type="term" value="P:nuclear pore complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043935">
        <property type="term" value="P:sexual sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21452">
        <property type="entry name" value="DLC-like_DYNLL1_DYNLL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000001">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019763">
        <property type="entry name" value="Dynein_light_1/2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01239">
        <property type="entry name" value="DYNEIN_LIGHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 11" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC45807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="96" mass="11101" checksum="210B0FE28E58B55C" modified="2014-04-16" version="1">MASEKSDTQKQDAQIKSADMSEEMQQEAIEVAQSAMEQFTIEKDIAQYIKKEFDSRKGATWHCIVGRNFGSFVTHETKHFIYFYLGHCAILLFKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2C3</accession>
    <name>W6Z2C3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbohydrate-binding module family 48 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_99066</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689386.1">
        <property type="nucleotide sequence ID" value="XM_007691196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2C3"/>
    <dbReference type="STRING" id="930090.W6Z2C3"/>
    <dbReference type="GeneID" id="19129391"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99066"/>
    <dbReference type="eggNOG" id="KOG1616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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            <dbReference type="ARBA" id="ARBA00022490"/>
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            <dbReference type="SMART" id="SM01010"/>
        </source>
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            <dbReference type="EMBL" id="EUC44125.1"/>
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            <dbReference type="Proteomes" id="UP000054032"/>
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    </evidence>
    <sequence length="597" mass="65653" checksum="778FD76F9FEFD6BB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2D2</accession>
    <name>W6Z2D2_COCMI</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">COCMIDRAFT_27521</name>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
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    </dbReference>
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    </dbReference>
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            <begin position="431"/>
            <end position="459"/>
        </location>
    </feature>
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            <end position="347"/>
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    </feature>
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        <location>
            <begin position="443"/>
            <end position="459"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="459" mass="50512" checksum="B76F8D9AACBB0894" modified="2014-04-16" version="1">MDGAPSSESHAVPPQLRQRMMLNRAATFGEVAQPSTPPAAVSRRRSSLVSDLSDTRPSLWSSTDNLLRTGAKYDMDRQEDAASDEPSRWIALPVVAAVVPAIIGLTVENGAVIATDVLILVLAGWFLHLSVKVPWDCYHDAQQRRYISDEADDDDTYNNTIREVDETDIHGIAEGVGDAASQEQADMSPAPSVTLPAQQEAREALKRSELLAFVGCFLGPLLGALLMHTVRGQLMRAEGIVSDANLSIFLLIAEIPPVNRLIKMRTERILHLQRIVRDAPRGAIRPADAQQLSQRIVELESRLDGASSSNNKNTSQIDVEKLSTEIRQTTQLQLDALNRAVRRYEKRHMAQSLQIEARFQDLEARLQDTLALAAAAARTGHRPGIITVTLSWIAGTISSMLQLIWDISMYPFRTAAIVLSVIKSMFIPEKRQPKPRAKGGQVNGHTSISSSRMQSKVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2E1</accession>
    <name>W6Z2E1_COCMI</name>
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        <recommendedName>
            <fullName evidence="13">Protein transport protein SEC22</fullName>
        </recommendedName>
    </protein>
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        <name evidence="18" type="ORF">COCMIDRAFT_27453</name>
    </gene>
    <organism evidence="18 19">
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the synaptobrevin family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC44145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007691117.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z2E1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_27453"/>
    <dbReference type="eggNOG" id="KOG0862">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054453_4_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="R-SNARE_SEC22"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SNARE complex subunit SEC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000014">
        <property type="entry name" value="Transport protein sec22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044565">
        <property type="entry name" value="Sec22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45837">
        <property type="entry name" value="VESICLE-TRAFFICKING PROTEIN SEC22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="16">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="17">
        <location>
            <begin position="134"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC44145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="215" mass="25280" checksum="35D90105AD35ECF6" modified="2014-04-16" version="1">MIKHTMISRLDGLILTASVDDEQTDAEFNEVKGKVKLVQRRLNRNSEPQASIESGSYTYHYLIEGDLCFLCICDRSYPRKLAFTYLSDLSREFTTTYQPQQYLSPTCRPYAFVEFDTFIQRTKKTYQDSRATQNLDKLNDELKDVTKVMTKNIEDLLYRGDSLERMGDISSRLREDSRKYKKAAVRINWELLLKQYGPVGGLAFIIIVFIWWRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2Q7</accession>
    <name>W6Z2Q7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_25912</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963973">
        <property type="protein sequence ID" value="EUC46037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687466.1">
        <property type="nucleotide sequence ID" value="XM_007689276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2Q7"/>
    <dbReference type="STRING" id="930090.W6Z2Q7"/>
    <dbReference type="GeneID" id="19120846"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25912"/>
    <dbReference type="eggNOG" id="KOG1001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_2_8_1"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF16">
        <property type="entry name" value="ATP-DEPENDENT HELICASE ULS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="309"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="659"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="851"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="51"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="740"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="740"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="792"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC46037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1020" mass="115232" checksum="2D5D74330CAA7A1F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z417</accession>
    <name>W6Z417_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_39544</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964063">
        <property type="protein sequence ID" value="EUC42374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691098.1">
        <property type="nucleotide sequence ID" value="XM_007692908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z417"/>
    <dbReference type="STRING" id="930090.W6Z417"/>
    <dbReference type="GeneID" id="19123706"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39544"/>
    <dbReference type="eggNOG" id="KOG3114">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059606_2_1_1"/>
    <dbReference type="OrthoDB" id="10256463at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:Golgi membrane"/>
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</entry>
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    <accession>W6Z464</accession>
    <name>W6Z464_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">phosphoinositide 5-phosphatase</fullName>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1250" mass="139660" checksum="768252C9B866644A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z486</accession>
    <name>W6Z486_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">BOD1/SHG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_97460</name>
    </gene>
    <organism evidence="4 5">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR055264">
        <property type="entry name" value="BOD1/SHG1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28034:SF1">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28034">
        <property type="entry name" value="SET1 COMPLEX COMPONENT SHG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05205">
        <property type="entry name" value="COMPASS-Shg1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="548"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="583"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="624"/>
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        </location>
    </feature>
    <feature type="domain" description="BOD1/SHG1" evidence="3">
        <location>
            <begin position="39"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
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            <end position="456"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="194"/>
        </location>
    </feature>
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        <location>
            <begin position="200"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="721" mass="80934" checksum="C7C80034FAC9A91D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4J5</accession>
    <name>W6Z4J5_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_103239</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_103239"/>
    <dbReference type="HOGENOM" id="CLU_2793610_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="68" mass="7236" checksum="C10CE98A09AC5E57" modified="2014-04-16" version="1">MGGTGAARAAPHVRGEPTSKEKTESQGEANELRPCQIGQLLTVRSHAWQNCAGECAQRECELKMGVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4Y5</accession>
    <name>W6Z4Y5_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_35543</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="1">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="19122805"/>
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    <dbReference type="eggNOG" id="KOG2451">
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Succinate-semialdehyde dehydrogenase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
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        <property type="entry name" value="Ald_DH_N"/>
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    </dbReference>
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        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
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        <property type="entry name" value="SUCCINATE SEMIALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldedh"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="29"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="501" mass="54732" checksum="20BD936D559983CF" modified="2014-04-16" version="1">MGSESKYQLPFKLNNPDLLHNLSFVNGDWVQSKSGKTFEVVDPGTGKPWIECPTNDASDVEDAVKSSYDAFQKYKNISPRQKAQMLFKWDALIKENREDIATILVYETGKPRAEAYGEIDYSTGFTWWFAGEAERIQGTVFTPALPNRRVFTIKQPLGVAVALVPWNFPIAMVLRKAGAALAAGCTMIVKPSPETPITILTLAYLAQKAGFPNGALNVLTTDLDKTPELSEALCRHPLVNKVTFTGSTRVGKLVARICADNLKKVTLELGGNCPVLIFDDANIEQAVGQIFALKYRHAGQACITANRIYVQSGIFDTFLQRWNAETQKLVVGHGADEKTTMGPVTTPRGIEKAVTLVEDAKKKGAKIHTGGNKIEKDGGYFFEPTVISDVTPDMDLAKEEAFAPICTFIKFSTEDEAVKAANDTSMGLASYCFTKNVDRTWRLFENLEAGMIGLNTGNGSAAESPFGGIKQSGYGKESGKDVAVNEYLITKTGTFTLEEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z592</accession>
    <name>W6Z592_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_102752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964051">
        <property type="protein sequence ID" value="EUC42729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690765.1">
        <property type="nucleotide sequence ID" value="XM_007692575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z592"/>
    <dbReference type="STRING" id="930090.W6Z592"/>
    <dbReference type="GeneID" id="19118149"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102752"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005562_3_1_1"/>
    <dbReference type="OrthoDB" id="3142841at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF5">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01222)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="564" mass="62983" checksum="3D92E3F9BCBE7560" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5G0</accession>
    <name>W6Z5G0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_5589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC45190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5G0"/>
    <dbReference type="GeneID" id="19124661"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5589"/>
    <dbReference type="HOGENOM" id="CLU_903171_0_0_1"/>
    <dbReference type="OrthoDB" id="3801367at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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        <property type="entry name" value="AN11006-like"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13013">
        <property type="entry name" value="F-box-like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="15"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="308" mass="35597" checksum="DE74BF18042A100F" modified="2014-04-16" version="1">MAPTTRNVQSFYDFLAHSAEIRNFIYEFAIAAETPDTPEGDVLLRKADPKPYTTRPWKFFGLTQTCRQIRAEFRPLWMRNTSIRFMGLEDSVSFISTFMPAIAEFKHAPECFTIGTAYKVGRDSLCDITLLFRMDAFCPYFCLSFSPFEVIMGRPPPDERICPCCEEHFNPHTGEWSGTGIEEDCICIPSDADLQDRVDWEGFRDEELIHMDPLFEIQSASEAWWKDLQDDKISIYMTASLSEVLPRFRIEYKAQGPRNGSSRRLVRELLSRWGLRVLIEDYENVTFAVKYGESSEEKSGDVEVEVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z641</accession>
    <name>W6Z641_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme Q-binding protein COQ10 START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_96020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z641"/>
    <dbReference type="GeneID" id="19128770"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96020"/>
    <dbReference type="eggNOG" id="ENOG502S6PP">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069867_0_2_1"/>
    <dbReference type="OrthoDB" id="509124at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07822">
        <property type="entry name" value="SRPBCC_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="24929" checksum="84D50D1B6E8B9F83" modified="2014-04-16" version="1">MADDKIWPPANGLTTKVVPRDKAILELPYSTTVHAPAHVVFDTLVRTSNYSAWNTWIPSVRIISQPPPRNTTEEQDGSRMRVGTEMEFNVVMDASKPDSITHTLLKVSDISTPDAPSSYLSAEELADPSFTADLGKVYRVAWTSNGGMMGFAPQIERFHEVIVTSEDTCEVRNWELMSGMTARLVKLFMLETLQGKVRLWCEDLKKYCERVYAEGKAGGGAAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z692</accession>
    <name>W6Z692_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_26523</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC12A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688183.1">
        <property type="nucleotide sequence ID" value="XM_007689993.1"/>
    </dbReference>
    <dbReference type="GeneID" id="19120946"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26523"/>
    <dbReference type="eggNOG" id="KOG1288">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001883_4_0_1"/>
    <dbReference type="OrthoDB" id="2020542at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990816">
        <property type="term" value="C:vacuole-mitochondrion membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015379">
        <property type="term" value="F:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006884">
        <property type="term" value="P:cell volume homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055064">
        <property type="term" value="P:chloride ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055075">
        <property type="term" value="P:potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034486">
        <property type="term" value="P:vacuolar transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000013">
        <property type="entry name" value="Solute carrier family 12 member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018491">
        <property type="entry name" value="SLC12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004842">
        <property type="entry name" value="SLC12A_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827:SF72">
        <property type="entry name" value="GH08340P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03522">
        <property type="entry name" value="SLC12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="535"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="132"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="10">
        <location>
            <begin position="620"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="10">
        <location>
            <begin position="1303"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="716"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1014"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1125"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="727"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1055"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1080"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1125"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1139"/>
            <end position="1156"/>
        </location>
    </feature>
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        <location>
            <begin position="1169"/>
            <end position="1183"/>
        </location>
    </feature>
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        <location>
            <begin position="1241"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1269"/>
            <end position="1285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1370" mass="149812" checksum="25A6C63A03C42554" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6K5</accession>
    <name>W6Z6K5_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">DUF2306 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_94973</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6K5"/>
    <dbReference type="STRING" id="930090.W6Z6K5"/>
    <dbReference type="GeneID" id="19128552"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94973"/>
    <dbReference type="eggNOG" id="ENOG502RYBX">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054818_0_1_1"/>
    <dbReference type="OrthoDB" id="193478at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="38914" checksum="F9DCABBB855E9BBF" modified="2014-04-16" version="1">MVAKPPSSSAFARKVANPLGFTKTYNFWLYFVFGGALLGFSLARLQYLGFSSKFCPAAGPSSTGNSAAPGECYYYLNFNRFKVGILLHLGGVLPAGMIAVMQFTPVIRHRWLTLHRIGGYASLLLYLISLVGALMIIRHAFGGGLDVQSSLGALGFTTLGCFIISYINVKKLQIEQHRAWMLRGWFYAGCIITTRIIMIISAQIIKNSGYYTVWPCVKIAATIEDDIDLVTSYPACSAFANGSNPDAVSAVAATIGSGDRANTGAALNIAFGMAVWVAFALHAIGVEIYLHLTPREAQRLRQVSYQKQLEAGMRNPGSAGLTSDRLGDAERWTPDASRKDSTSPLTPGTPEPNPRVERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7N0</accession>
    <name>W6Z7N0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_100395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964024">
        <property type="protein sequence ID" value="EUC43589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689883.1">
        <property type="nucleotide sequence ID" value="XM_007691693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7N0"/>
    <dbReference type="STRING" id="930090.W6Z7N0"/>
    <dbReference type="GeneID" id="19117667"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100395"/>
    <dbReference type="eggNOG" id="ENOG502QRM1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024934_0_4_1"/>
    <dbReference type="OrthoDB" id="5386330at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="404" mass="45501" checksum="E4B0EB9F25533D24" modified="2014-04-16" version="1">MVKTRRAHRKSRGGCRECKRRRIKCSEGKPSCAHCTRHHVSCVYDIPGTPIQPASSKNSPAQSENLASRSSSPVRHTSKPPYIDLSRPQHLFDLKDMELLHHWNLVTSASMVDSLSAAEVWRIHFPRIAFQHPYVMHSLLSIAALHVAYLNPSRRQSSIIHAGCHHAKALEGFHEAINHIGADNGDAVFTTATLLFFHAFITLSQLRYDFDQQIEGCSRVSRILGAEWIPLLRGVGAVLLPALEHVRRGPLSPMMGLGNWEAVNPDDHPTADDEKLRGIGQLWKDDKNAEVYETSLHLLRKFWAWMVQLQNSGSNASGECGYHGIGSGPFMWLFITPEMFFDLQRQRQPAALVLFAHFGAFLQKLNGYWWAEGCGKTIVSAVDDCLGSYWEPWTRWPKEVVGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7T1</accession>
    <name>W6Z7T1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_38437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964023">
        <property type="protein sequence ID" value="EUC43634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689836.1">
        <property type="nucleotide sequence ID" value="XM_007691646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7T1"/>
    <dbReference type="GeneID" id="19123465"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38437"/>
    <dbReference type="eggNOG" id="ENOG502RG4I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_918233_0_0_1"/>
    <dbReference type="OrthoDB" id="3796171at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="303" mass="33111" checksum="B2E4B88B0B9B074D" modified="2014-04-16" version="1">MPKSNGCRTLLLLTPPILLLFPTAALISILERISKNTFYSHLQRSFRTGAFQLVLARPGGGPGIGLTLDFNHAPILFILGICVIAYAVTVLSAAGIWQLKKVEGTARHERVWVWVVLVANVVMIGASLAGFGYATSVQAADGTWSDYEDAGRPDQELTRETWACQIHSLFPGEGWAGTACGASQAMRYLLLPMAVAAMAVLGSLWVLVRGRGGFKWVFGGQGRYAGFRGAYELQPQEQNTVYSEPPPPVQQWRGQPGQQWVPQAYQPYGQQLYGQQPVQPWAPQPVAQVSKSGANVEQRPVYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7U5</accession>
    <name>W6Z7U5_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_110688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964261">
        <property type="protein sequence ID" value="EUC39751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693733.1">
        <property type="nucleotide sequence ID" value="XM_007695543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7U5"/>
    <dbReference type="GeneID" id="19119640"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110688"/>
    <dbReference type="HOGENOM" id="CLU_2612406_0_0_1"/>
    <dbReference type="OrthoDB" id="3880115at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="79" mass="9057" checksum="D5DFD490D3965E0F" modified="2014-04-16" version="1" fragment="single">MSPFFQLPRELRDLIYDYYVRCDGGYVYDVEARKFRQADGGPVFNALALTCRQAAFELEGLAFQVNTITFSAAYTESLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8E0</accession>
    <name>W6Z8E0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_10061</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964216">
        <property type="protein sequence ID" value="EUC39961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693521.1">
        <property type="nucleotide sequence ID" value="XM_007695331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8E0"/>
    <dbReference type="STRING" id="930090.W6Z8E0"/>
    <dbReference type="GeneID" id="19117710"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10061"/>
    <dbReference type="eggNOG" id="KOG4159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017137_2_1_1"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031142">
        <property type="entry name" value="SPX_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45978">
        <property type="entry name" value="SPX DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45978:SF7">
        <property type="entry name" value="SPX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SPX" evidence="7">
        <location>
            <begin position="1"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="365"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC39961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="52889" checksum="7DD663E0D0C781A4" modified="2014-04-16" version="1">MKFGHVFKQTLRDEGFPPDWVDSAISYSQLKKCIKRLTDELRQVGLDPPTLSKLLKHVEDYNASTEHHDNQERPFEYILNPHGSHDDDDDASQSPRAFHPKLLFYVDETSGEVMGAKLDNDTRNKLHLLAVETGMSDMRVLDDSADTPESPTAANAPGNRPGCRTVLVPITSDTEFFTRLTSEVSGLEKLQEREQKRMNVQIEALGKQVAKLTDPDRRTTRKMLTTWRKIFQIYVEEGIFFGTTELDHKSHDSEKAMARLAIFSNKIAKAGLVEQLKKKENLTALNTFMHINREILQGLRFGEINHNAMLKILKKFDKRTALGVKSTFPRQVEYPEFSEHLAKAVCAEVNTQILSHVPQIDDYSCPMCMEIQWRPVKLSCNHTFCIRCLIVMQNNKQYNCPFCRQKTIFDANSDNLDTEKAAFLKRWFPEEVKDKQRYNEKMAGVDQYGEVYANEKCNVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z958</accession>
    <name>W6Z958_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_41430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964186">
        <property type="protein sequence ID" value="EUC40211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693270.1">
        <property type="nucleotide sequence ID" value="XM_007695080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z958"/>
    <dbReference type="GeneID" id="19124057"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41430"/>
    <dbReference type="HOGENOM" id="CLU_133917_0_0_1"/>
    <dbReference type="OrthoDB" id="10508512at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="133" mass="14380" checksum="C6899B77FEE10CF6" modified="2014-04-16" version="1">MAPMPCGGRVGSFATNVEQALFAFAASSLRDRSTKLLGILQARAQDWPRQGVDRLREGLVCCQRHISGYHGRFENRRGAMIRACAADDGQSCRWSVLLDQVGLALPLALLEKPLSAGFLGRRLPGGQGGRAIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z965</accession>
    <name>W6Z965_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_4351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686874.1">
        <property type="nucleotide sequence ID" value="XM_007688684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z965"/>
    <dbReference type="GeneID" id="19124211"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4351"/>
    <dbReference type="HOGENOM" id="CLU_052827_4_1_1"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF3">
        <property type="entry name" value="THIOESTERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G03960)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="23301" checksum="619F3CAAC7A94CEC" modified="2014-04-16" version="1">MMTATSEHLQAFAPLSWATPYLTSPKWMVCDRERGSEPGEDTDRFCRDTMRANHGVQHWVELHEQPSNPGGKITKSISLVKFGTGLNGFPGICHGGALFTLMDEAMCYIVVANTVVEHGVAFMKAGEEQWRLQLFHGKLAQEILKGRLVTANMDTRVLAPVLCPGIVGIETDVLEDKGNKMRIRAIMRDRQGKPVVQTEGLWVRVGGAANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z976</accession>
    <name>W6Z976_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964184">
        <property type="protein sequence ID" value="EUC40231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693253.1">
        <property type="nucleotide sequence ID" value="XM_007695063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z976"/>
    <dbReference type="STRING" id="930090.W6Z976"/>
    <dbReference type="GeneID" id="19121744"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30801"/>
    <dbReference type="eggNOG" id="ENOG502RZF1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026455_2_0_1"/>
    <dbReference type="OrthoDB" id="4179406at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="595" mass="65665" checksum="9078B10EEE4649CC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z987</accession>
    <name>W6Z987_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial fission 1 protein</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">COCMIDRAFT_93178</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FIS1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="KI963968">
        <property type="protein sequence ID" value="EUC46333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687189.1">
        <property type="nucleotide sequence ID" value="XM_007688999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z987"/>
    <dbReference type="STRING" id="930090.W6Z987"/>
    <dbReference type="GeneID" id="19128217"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93178"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3364">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021597_2_1_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000127">
        <property type="entry name" value="E3 ubiquitin-protein ligase RNF181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000179">
        <property type="entry name" value="Mitochondrial fission 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028058">
        <property type="entry name" value="Fis1_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14852">
        <property type="entry name" value="Fis1_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="14" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="21">
        <location>
            <begin position="514"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="219"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="311"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="560"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="313"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC46333.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="624" mass="67421" checksum="1C3DA2D4A389B7EB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9G5</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Dhillon B."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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</entry>
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                <person name="Grimwood J."/>
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                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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    <accession>W6ZA63</accession>
    <name>W6ZA63_COCMI</name>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
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        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SWC4 family.</text>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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    <dbReference type="PANTHER" id="PTHR12855:SF10">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
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        <location>
            <begin position="141"/>
            <end position="242"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="506"/>
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        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC46855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="647" mass="71524" checksum="C75B8B1DE637D956" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB18</accession>
    <name>W6ZB18_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GTP-binding protein ypt1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_33651</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Preautophagosomal structure membrane</location>
            <topology evidence="8">Lipid-anchor</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684525.1">
        <property type="nucleotide sequence ID" value="XM_007686335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB18"/>
    <dbReference type="STRING" id="930090.W6ZB18"/>
    <dbReference type="GeneID" id="19122373"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33651"/>
    <dbReference type="eggNOG" id="KOG0084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_10_1_1"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01869">
        <property type="entry name" value="Rab1_Ypt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000069">
        <property type="entry name" value="Ras GTP-binding protein YPT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057289">
        <property type="entry name" value="Rab1/Ypt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00060489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00074496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="216" mass="23876" checksum="C163FB09DC6D4B9C" modified="2014-04-16" version="1">MNPEWYVTSARSPPPQADEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTVKLQIWDTAGQERFRTITSSYYRGAHGICVVYDVTDMDSFNNVKQWLQEIDRYATEGVNKLLVGNKSDMADKKVVEYTVAKEFADSLGIPFLETSAKSATNVEQAFLTMARQIKERMGTTTANTKPTVPIGQGQGVQSGSGGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBF3</accession>
    <name>W6ZBF3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_50746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686348.1">
        <property type="nucleotide sequence ID" value="XM_007688158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBF3"/>
    <dbReference type="GeneID" id="19124489"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_50746"/>
    <dbReference type="HOGENOM" id="CLU_1450917_0_0_1"/>
    <dbReference type="OrthoDB" id="3758401at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="187" mass="20920" checksum="46C98794FC4C657D" modified="2014-04-16" version="1" fragment="single">SPTKPSPAPINNETENYTTAFPSLPPTTPATHAHIINLQSPPPTPTLQDTLVTTLYHTSPATLSHFLDPTVHTFKQVLGKSDIKLVIWRKGVEVFIGMFENHTQLKTFRFLHLAGLLVGYDGSWRVTCVAVNAYCATRWSDVWAGKFECKGGVDVMRVYRDDGEEEEGVERGVREMAEKVMAGKFWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBK7</accession>
    <name>W6ZBK7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_90280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686093.1">
        <property type="nucleotide sequence ID" value="XM_007687903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBK7"/>
    <dbReference type="STRING" id="930090.W6ZBK7"/>
    <dbReference type="GeneID" id="19127652"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90280"/>
    <dbReference type="eggNOG" id="ENOG502SZKE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182434_1_0_1"/>
    <dbReference type="OrthoDB" id="5375886at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="70" mass="7315" checksum="91C939851DD4C866" modified="2014-04-16" version="1">MSAPNAGRQSPDPERQSGAQAGQISDNVNQQGAGPKEGAEKSSDNTKDALSSNPEHPLKEHSEETTSKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBN0</accession>
    <name>W6ZBN0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Store-operated calcium entry-associated regulatory factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Transmembrane protein 66</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_90806</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SARAF family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686262.1">
        <property type="nucleotide sequence ID" value="XM_007688072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBN0"/>
    <dbReference type="STRING" id="930090.W6ZBN0"/>
    <dbReference type="GeneID" id="19127758"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90806"/>
    <dbReference type="eggNOG" id="ENOG502QT6Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046802_1_0_1"/>
    <dbReference type="OrthoDB" id="20303at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006816">
        <property type="term" value="P:calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001256">
        <property type="term" value="P:regulation of store-operated calcium entry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009567">
        <property type="entry name" value="SARAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929:SF0">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06682">
        <property type="entry name" value="SARAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="206"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="264"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="264"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC47203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="319" mass="33946" checksum="D2B43AF115BDA1F2" modified="2014-04-16" version="1">MHISNFLYPALLAASGAEALRSDKVKLSNIQSLTLRKGQQTSARRVDPIPQLKCIGGSARGLYEPEIMRCKNSGSDYDENSIQWTCTASLPEEFKLGSTDVICEGYDYPEDPYILKGSCGVEYRLILTDKGRERYGKGRGGWQGDDDDRRDGPRTTGEKVAGVLFWMLFGGVVLWMIYSALRNRAEAQNGGAAGGNRPGWGGGGGGGGWGGGYNDDNNDPPPPYYPNDPRNSKSGYGTTQGWRPGFWSGAAGGAAAGWAAGQFANRGNSSRSGRWGSNSGSGSGSRWNNGGEGSSRSSSGDSYSSTRHESTGFGGTSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE59</accession>
    <name>W6ZE59_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="5 16">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_5096</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:10868"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:64615"/>
            <dbReference type="EC" id="2.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Endoplasmic reticulum membrane</location>
            <topology evidence="1 16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="5 16"/>
    <dbReference type="EMBL" id="KI963978">
        <property type="protein sequence ID" value="EUC45764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687713.1">
        <property type="nucleotide sequence ID" value="XM_007689523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE59"/>
    <dbReference type="STRING" id="930090.W6ZE59"/>
    <dbReference type="GeneID" id="19124496"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5096"/>
    <dbReference type="eggNOG" id="KOG0831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023995_3_1_1"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="UniPathway" id="UPA00282"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006672">
        <property type="term" value="P:ceramide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035356">
        <property type="term" value="P:intracellular triglyceride homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC45764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="495" mass="55500" checksum="F991EA478C38E9A0" modified="2014-04-16" version="1">MSLNPEPSAPEERAEHNLPPKSYADAAEEALQSGPQSHANGEGRTDEVKTNGIHVASDEEQTSHEGIGQDGSPKSPTARGHRRVSSRSSHKSSKSTHDNQLPKDIMESHTNGNGNALTTVKPSQESELPPRDRRTDLKRRDSELTAGRQAGASWSKSKIRFAPMNVPLQRRLQTLAVLMHTLSIVGSLAIFFFLCSIPLLWPILLPYTVYVLFSDAGTSGELSLRSEWFRRLPVWSLFASYFPARLHRSQELEPTRKYIFGYHPHGIISHGAFAAFATEALGFSQLFPGITNTLLTLDSNFRYPIYREYALRLGMASVSRESCENILSKGGQNGEGMGRAITIVVGGAAESLDARPGEIKLVLHRRKGFVKMAIRTGADLVPVLSFGENDIYDQVDTESHPYIHKFQLLVKKFMGFTVPIFHARGVFNYDVGMMPYRRPINIVVGRPIRVVQDEHPNNDYIDQVHQQYVDELMRVWNEHKDTFARNRTGELEIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEH6</accession>
    <name>W6ZEH6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_23782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685014.1">
        <property type="nucleotide sequence ID" value="XM_007686824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEH6"/>
    <dbReference type="GeneID" id="19120494"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23782"/>
    <dbReference type="HOGENOM" id="CLU_1970149_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="127" mass="13018" checksum="95049D847A6EEFC1" modified="2014-04-16" version="1">MKAPSSHRVAFAARRGDNGALSNQSRSQQWDEWIAQRFSACNPMIQGQKAKLSGDKEPTSAHAPLSAVAAGETPLAGPAANHGSVPGSRWGRLFRLGHGAAPAALAPEGPASGIVGTKGSHGKEKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF71</accession>
    <name>W6ZF71_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_4776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963971">
        <property type="protein sequence ID" value="EUC46154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687330.1">
        <property type="nucleotide sequence ID" value="XM_007689140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF71"/>
    <dbReference type="STRING" id="930090.W6ZF71"/>
    <dbReference type="GeneID" id="19124372"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4776"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1834808_0_0_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="69"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="140" mass="14965" checksum="86FC0022B3E961C7" modified="2014-04-16" version="1">MSDDRDAQDYLRLIWFFESVLSHVERGADYIPSQLQPLPTVQPREYGAPAATQNPYDAWSHQCTLSAAAPSSHCLQGRAVTIKDNICVQGLPATLGAPAPILSNQNKYPVSPIDATVVSRVLAAGGTIKGTSTCDTALEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFB5</accession>
    <name>W6ZFB5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleolar GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_86841</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684854.1">
        <property type="nucleotide sequence ID" value="XM_007686664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFB5"/>
    <dbReference type="STRING" id="930090.W6ZFB5"/>
    <dbReference type="GeneID" id="19126945"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86841"/>
    <dbReference type="eggNOG" id="KOG1490">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011784_4_1_1"/>
    <dbReference type="OrthoDB" id="415015at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="8">
        <location>
            <begin position="168"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="549"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="595"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR038919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC48603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="654" mass="74184" checksum="CCD7DC43F93F01C2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFZ9</accession>
    <name>W6ZFZ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_81089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC50737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFZ9"/>
    <dbReference type="STRING" id="930090.W6ZFZ9"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_81089"/>
    <dbReference type="eggNOG" id="KOG1300">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2228at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
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        <property type="entry name" value="Sec1-like"/>
    </dbReference>
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        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="618"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="638"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="692"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="702"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="714" mass="81482" checksum="E3B8B2EB7FFE9128" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG12</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_33639</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963936">
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    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_33639"/>
    <dbReference type="HOGENOM" id="CLU_2941367_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="60" mass="6422" checksum="91C5C4C72638707D" modified="2014-04-16" version="1">MPTHVEPYETLEGALPHRTQAHASEADNGQALRTPVAVPEAARNEFGSLGSDGAWHVQDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG53</accession>
    <name>W6ZG53_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_80893</name>
    </gene>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG53"/>
    <dbReference type="STRING" id="930090.W6ZG53"/>
    <dbReference type="GeneID" id="19125762"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80893"/>
    <dbReference type="eggNOG" id="ENOG502SU16">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055859_5_0_1"/>
    <dbReference type="OrthoDB" id="5215637at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889806" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC50792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="26844" checksum="7B71C056FDCC5406" modified="2014-04-16" version="1">MVGCRSLLTVLVTLAAVVKSQQCYGVDGSLLDKSYTPCNPSANVSGCCASGDICLSNGLCMGTQGASIGVIFSRGCTDSTGKDIACPQQCSSASSNSNSASTVTAWQLQTCDSGEYCCRAANSTKSCCNNPTAPRVTSPLSATLQIPAPASTPATNSPDQEPASSSPMSTPPATSDCQEEKTHTAIVGAILGGLLGGIILGLVVAVRWMYKRERRQRRLKEHYETQMSKTNAYRKALEETVGSARPSLSLEQVVSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG95</accession>
    <name>W6ZG95_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_81236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682785.1">
        <property type="nucleotide sequence ID" value="XM_007684595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG95"/>
    <dbReference type="GeneID" id="19125829"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81236"/>
    <dbReference type="HOGENOM" id="CLU_1880310_0_0_1"/>
    <dbReference type="OrthoDB" id="3683450at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="136" mass="15370" checksum="23A8FEA57C11074E" modified="2014-04-16" version="1" fragment="single">VFEGVSTTEQEKGRYPGNIAIRAFSLVFPLILSFVLHNQYPFFGFSISCVSFPSITIYLYLSLRHFALFTLHLDELGMVFFSSTPGCGTRCRSILSHVSLRNFDSVIPRYYIQSFQTVAEFTARTAPLPTPMFSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGA9</accession>
    <name>W6ZGA9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LAMTOR domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_103272</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Bipolaris</taxon>
        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">ATCC 44560</strain>
        </source>
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        </subcellularLocation>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:cellular response to amino acid stimulus"/>
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        <property type="term" value="P:endosomal transport"/>
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        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="6">
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023139"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="16507" checksum="429B16434BAEEB29" modified="2014-04-16" version="1">MGVCASCLGGQRTSDIDQSDASHLLGDQYQPNYGTASSTHNVPQPDPEELRRQRENLERICAETNEQLIPVSQPSALPEVSEQPSKNDEYAHLFNERFKSIRHGRPASAGDNEDDETTWLENAVGSQGEDELDQIKPANGKLTIQFGQR</sequence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Wu D."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
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            <end position="76"/>
        </location>
    </feature>
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            <begin position="54"/>
            <end position="517"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
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        <source>
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        <source>
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        </source>
    </evidence>
    <sequence length="558" mass="61123" checksum="0606C64F361726E6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGN8</accession>
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    </protein>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
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    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:mitochondrial translational termination"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="entry name" value="Related to MRF1-peptide chain release factor, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
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        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
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        <property type="entry name" value="Prokaryotic/Mito_RF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804:SF7">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="4">
        <location>
            <begin position="276"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC49175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="416" mass="45939" checksum="FBB7D8D0C4692AB8" modified="2014-04-16" version="1">MLAAPWICRGCLSRIGRPLLRRSVRLQSSAASPESIPPALLARAQAITSEHKVLTEKLSNGFNTRAAKKLGEYSPIVNALGEWNKANESVAELASMIHDPSTDPELRSLASDDLAETRTQLATASQNLITSLVPVHPFAHLPCLLEIRPGAGGSEAAIFAGDLFRMYQAFCNRNGFRTNILKYENVNGTTEAGVPLSEAIIEVEDENAYGVFRCEAGVHRVQRVPATETKGRTHTSAASVHVLPSLQENSAEEQDFDDPESDYYIDPKEVKVEVMRASGAGGQHVNKTESAVRLTHTPSNTVVAMQDSRSQHKNKEKAWTLLRSRIAQSRREKREEEMANMRRSVIGVAKMGRGDKVRTYNWGQQRVTDHRSGTTVHDLDDVMQGGQTLSTVMESVRTWLMERDVEALIADEAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGU8</accession>
    <name>W6ZGU8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="2">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_23047</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684165.1">
        <property type="nucleotide sequence ID" value="XM_007685975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGU8"/>
    <dbReference type="STRING" id="930090.W6ZGU8"/>
    <dbReference type="GeneID" id="19120366"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23047"/>
    <dbReference type="eggNOG" id="KOG3157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059988_2_0_1"/>
    <dbReference type="OrthoDB" id="10264196at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06822">
        <property type="entry name" value="PLPDE_III_YBL036c_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000007">
        <property type="entry name" value="Pyridoxal phosphate homeostasis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine racemase N-terminal" evidence="5">
        <location>
            <begin position="19"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2 3">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="269" mass="29781" checksum="888E9A53FB3DE1C3" modified="2014-04-16" version="1">MAEDMQINPQRAKQLSENIASITARINAASKGTKPVRLIAVSKLKPANEILALHQPPNPLQTHFGENYVQELLEKANLLPRSIHWHMIGGLQSNKCKHLAEQIPNLWCVSSVDTEKKANELEKGRKALLEKDKEASRLRVMVQVNTSGEESKSGVEPKDALALCRHVVDKCPHLQLAGFMTIGAIARSKAMTEENENEDFVALRETRDQVAEALGWDKQKLELSMGMSADFEGAIRMGSDEVRVGSEIFGERPPKKDAVVKEEVAGEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI23</accession>
    <name>W6ZI23_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_84222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683908.1">
        <property type="nucleotide sequence ID" value="XM_007685718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI23"/>
    <dbReference type="GeneID" id="19126424"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84222"/>
    <dbReference type="HOGENOM" id="CLU_1854898_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="138" mass="15053" checksum="9485E24363FC792C" modified="2014-04-16" version="1">MSGSYDSQINSISLRNEPYHPPIPHRQSQHFVQPQPYGYPGLSQPTQGPYCPYPPGSPAQQPYAPYPQHAEISSPVSTQGSQYTESSSPYQPWDTPPSSVSGFTSAKKTNETRGNRWASGGYDGEGYNGEGYNGEGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIK5</accession>
    <name>W6ZIK5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peptide transporter PTR2-A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_100969</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964030">
        <property type="protein sequence ID" value="EUC43406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690091.1">
        <property type="nucleotide sequence ID" value="XM_007691901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIK5"/>
    <dbReference type="GeneID" id="19117775"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100969"/>
    <dbReference type="eggNOG" id="KOG1237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004790_4_1_1"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000085">
        <property type="entry name" value="MFS peptide transporter Ptr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
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        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="191"/>
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        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
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        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
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        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
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        <location>
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            <end position="394"/>
        </location>
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            <end position="441"/>
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        </location>
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            <end position="519"/>
        </location>
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            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="581"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        <source>
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        <source>
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        <source>
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        </source>
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        </source>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
    <sequence length="621" mass="68512" checksum="FA8415B139937750" modified="2014-04-16" version="1"> </sequence>
</entry>
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            <taxon>Pleosporales</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
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        <location>
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            <end position="1055"/>
        </location>
    </feature>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1264" mass="140608" checksum="573848496E3BA654" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIW8</accession>
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        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
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        </recommendedName>
    </protein>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
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                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
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        <reaction evidence="8">
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            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
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            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687904.1"/>
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    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CMGC/SRPK protein kinase"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Protein_kinase_ATP_BS"/>
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        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="125"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="282"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="78"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="303"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC47364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="627" mass="68760" checksum="B02767F88730DA26" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIZ6</accession>
    <name>W6ZIZ6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIZ6"/>
    <dbReference type="GeneID" id="19126258"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83445"/>
    <dbReference type="eggNOG" id="ENOG502S1N8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068116_0_0_1"/>
    <dbReference type="OrthoDB" id="2140489at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36986">
        <property type="entry name" value="UPF0643 PROTEIN PB2B2.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36986:SF1">
        <property type="entry name" value="UPF0643 PROTEIN PB2B2.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30891" checksum="D51AC18F35A45E98" modified="2014-04-16" version="1">MEKPGYTIALPAQAPDIKEPSVKITELPPTPPSLNKSIQLRSVTLRDPNLITTDFDAHRFQAAAYTQLISTSIPKFPTQAPAPTTPPGSPPSDNLITSPYNKPGHYLSLSTPPLPLPSLFLAIALTSLQPTLPTYATAPYTSALNLDAVLDVLRALVKSEGVEWPETRFYVVVFRSKLKENIDNDYLYKLDEESHREACESGGLLKYWFGKSDAERRNLATCFWHSREDAYRGGLGPWHKKARAAGRELYEHITFTTHWFTVLEGAKEYTFEDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKA4</accession>
    <name>W6ZKA4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_957</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682978.1">
        <property type="nucleotide sequence ID" value="XM_007684788.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZKA4"/>
    <dbReference type="GeneID" id="19128710"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_957"/>
    <dbReference type="eggNOG" id="KOG0298">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003233_0_1_1"/>
    <dbReference type="OrthoDB" id="2801544at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF51">
        <property type="entry name" value="SNF2-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="1022"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="920"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1213"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="920"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="950"/>
            <end position="976"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1285" mass="142886" checksum="E5D98BBC591E84AB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKW7</accession>
    <name>W6ZKW7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_21709</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682655.1">
        <property type="nucleotide sequence ID" value="XM_007684465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKW7"/>
    <dbReference type="GeneID" id="19120109"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21709"/>
    <dbReference type="eggNOG" id="KOG1303">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027816_4_2_1"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000039">
        <property type="entry name" value="Neutral amino acid transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF683">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="45"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="468" mass="50229" checksum="E9280E056CE2A336" modified="2014-04-16" version="1">MGFFNDNKADDTEYGSQLKAEDTNAQGQTDAVFGEVVEGGPNYRSVSWWGSSIIMMKTQIGLGVLSIPAAFDALGLIPGIISLLAIGLITLWSGYMVGTFKMRHPETYGIEDVGQKLFGRAGREVLGLAFALLWTCVAGSGMLGISIGLNSLSDHGTCTAVFVAVACFVGFALASIKTLGKLSWIAWIGLAGIMSAIITLTVAVSIQDRPSAAPQFGPWQSDFELFKSPTFAEAAAALSSIVFAFCGIPAYFNVVSEMKDHKDYFKALSLCQFVMTSIYIAIGVVVYYYCGSYVASPALGSAGVLMKKVCYGLALPGLLASVVLVIHLVAKYFFIRTLRGTKHLSRPTAKHWITWFSYTGAVSLTAYIIASAIPVFGGLVSLVGALLGTLMSFQPMGCMWLYDNWHRSNRDWRWKGMVAWSIFVIVSGTFLLIGGTYGSLVGIIDSYNKNGGTKPWSCADNSNSSGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZL19</accession>
    <name>W6ZL19_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dicer-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">COCMIDRAFT_80904</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="17 18">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682742.1">
        <property type="nucleotide sequence ID" value="XM_007684552.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZL19"/>
    <dbReference type="GeneID" id="19125763"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80904"/>
    <dbReference type="eggNOG" id="KOG0701">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000907_4_3_1"/>
    <dbReference type="OrthoDB" id="416741at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050688">
        <property type="term" value="P:regulation of defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18034">
        <property type="entry name" value="DEXHc_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd18802">
        <property type="entry name" value="SF2_C_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000015">
        <property type="entry name" value="Dicer-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dicer-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dicer-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056755">
        <property type="entry name" value="DSRM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF62">
        <property type="entry name" value="DICER-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24995">
        <property type="entry name" value="DSRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-0930">Antiviral protein</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="13 18" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="22">
        <location>
            <begin position="124"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="23">
        <location>
            <begin position="455"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="24">
        <location>
            <begin position="646"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="PAZ" evidence="21">
        <location>
            <begin position="893"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="20">
        <location>
            <begin position="1041"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="20">
        <location>
            <begin position="1280"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1555"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1558"/>
            <end position="1568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
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        <source>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50760.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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    </evidence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
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        <source>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">ATCC 44560</strain>
        </source>
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    <dbReference type="GO" id="GO:0000981">
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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        <source>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
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    <sequence length="782" mass="87337" checksum="0E0A154A1C479193" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPE6</accession>
    <name>W6ZPE6_COCMI</name>
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        <recommendedName>
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        <name evidence="6" type="ORF">COCMIDRAFT_84745</name>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684110.1">
        <property type="nucleotide sequence ID" value="XM_007685920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPE6"/>
    <dbReference type="STRING" id="930090.W6ZPE6"/>
    <dbReference type="GeneID" id="19126524"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84745"/>
    <dbReference type="eggNOG" id="KOG1251">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_4_2_1"/>
    <dbReference type="OrthoDB" id="271064at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030378">
        <property type="term" value="F:serine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018114">
        <property type="term" value="F:threonine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000005">
        <property type="entry name" value="Threonine dehydratase catabolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43050">
        <property type="entry name" value="SERINE / THREONINE RACEMASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43050:SF1">
        <property type="entry name" value="SERINE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="5">
        <location>
            <begin position="62"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="399" mass="42397" checksum="FF1DFE5A2BFC759C" modified="2014-04-16" version="1">MASIQIHPSLTRSNVEAAHALIKPHIHDTPVLTNTTLSNLASTPQTAEALKGTQWEGQKPAHPKINLFFKCENFQRIGAFKVRGAFHAVTRLIEKEGIDEVRKKGVVTHSSGNHAQALALAARTFSIPAHIVMPTISTPSKIAGTKAQNATVHFSGSTSTEREAVVATVVKDTGATLIPPYDDPNIILGQGTLALELEEQATKLLAQAATGNRKLDAVIAPCGGGGMLSGIATALHGTGIRVFGAEPSFQGGDDARRGVAAGERVTSVKTLTIADGLRTPLGEHNWSVISKQEYVAGLFAVTEDQIKKAMRLVLERMKCFVEPSAVVGLAVVLFNEDFRRLVAREAGQEGWNVGIVFSGGNTTVEAISKIFAEVPEVAKERQEGVLGIDGKREVENVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPY8</accession>
    <name>W6ZPY8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-alkyl-2-acetylglycerophosphocholine esterase</fullName>
            <ecNumber evidence="1">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_84513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684041.1">
        <property type="nucleotide sequence ID" value="XM_007685851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPY8"/>
    <dbReference type="GeneID" id="19126478"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84513"/>
    <dbReference type="eggNOG" id="KOG3847">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026278_0_0_1"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF14">
        <property type="entry name" value="PAF ACETYLHYDROLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887633" description="1-alkyl-2-acetylglycerophosphocholine esterase" evidence="5">
        <location>
            <begin position="23"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="403" mass="43612" checksum="DDF5BD31908CF931" modified="2014-04-16" version="1">MVAFLGVTITLLLAVISKSSHAVQIPGADNNHRFKVAVSHFPLTDTARKDPYFSTEDRRVMVSLFMPIPRDSCSSECQNSYMPPQTARIANEQFIVGGQRDIGVFEDMTYNACCKSSVSIDASKIPVVVLEPHVDTSRLLYSTMARFIAANGAAVVLVDHPGDASIVEFPNNGRRALDTVYNSGTVSLSNFSPLTAWNTTVTKALDTRISDIQFVLSQLNSIDLLKQHFSTFTFSSSTGLRTSNYGIVGHGLGGSVATSLGLTPSSSALFSINLQGTPPLLTSPVRNNPLFFFGRQDYRRENDIHWSTTWSYLTGPATEFDLNDSAIFDVSDLPVIVELARNEGGKPATRARGLSGGFPVQGAQAVTCFVETIVKAQFGLDSGGVLMNDCMRFFPGVVPYPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ71</accession>
    <name>W6ZQ71_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_84194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683931.1">
        <property type="nucleotide sequence ID" value="XM_007685741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ71"/>
    <dbReference type="STRING" id="930090.W6ZQ71"/>
    <dbReference type="GeneID" id="19126415"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84194"/>
    <dbReference type="eggNOG" id="ENOG502TH99">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_6_0_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF13">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="229" mass="27004" checksum="769DE724E1BFD549" modified="2014-04-16" version="1" fragment="single">APIRDLDRSFHIETFSPFNYSTSEYTMDPAEGDVDEKWMTLGQDSGHFLIPVSEGHKYDMDIKRHVTVPEGVAEEESFLVSLDVMHQIHCLDTLRENLWYNRDWYSVHQKQHPKLSVHKAHTNHCLNALRKRLMCFSDVTFLPMVYIDREGWTLPDFERRHKCHNFDATREWAYKHRMSDAAASYKKIAGPEKILTTFPGFYDIYPERNNPDHKDPDHGHSDNKEHHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQL2</accession>
    <name>W6ZQL2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_25871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963973">
        <property type="protein sequence ID" value="EUC45991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687455.1">
        <property type="nucleotide sequence ID" value="XM_007689265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQL2"/>
    <dbReference type="GeneID" id="19120835"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25871"/>
    <dbReference type="HOGENOM" id="CLU_2222775_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="106" mass="11520" checksum="3A97FEFAA8214BA0" modified="2014-04-16" version="1">MTCVLTIDHVEAKRTQPQAILGFELLDCMLDGTSFLADPLEAVTSAAAVLFGEVKNTMLIWLNLSNPTTHSLLVIGRNMHGQILKISPAHRTTSNAQLRTFAPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSN8</accession>
    <name>W6ZSN8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell surface protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_81576</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682872.1">
        <property type="nucleotide sequence ID" value="XM_007684682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSN8"/>
    <dbReference type="GeneID" id="19125901"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81576"/>
    <dbReference type="eggNOG" id="ENOG502S3WN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060605_0_0_1"/>
    <dbReference type="OrthoDB" id="5342184at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021986">
        <property type="entry name" value="Spherulin4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040:SF9">
        <property type="entry name" value="4-LIKE CELL SURFACE PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14080)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12138">
        <property type="entry name" value="Spherulin4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="27310" checksum="993B5045BDE7C274" modified="2014-04-16" version="1">MQSKVLLPLYIYPNPGAWDPLYTALSAHPHLHFLIILNPNSGPGTAPWWPNTDYLREIPRLNALPNVTTLGYVRATYCQRAHGDICSDICTYAERGREDAKMKVEGVFVDETVNLYSKEMKRYLDGIDGRVKAEDAFGGEGLVIHNPGTAVNKGLAAPGPDVTVVVETSYAHFASKEYQEWLATSPYGRERAAYMVHSVPEDQVEGLTRALRKKAAYLFVTSATSEFYEKFGDSWDKFVAVMAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTE3</accession>
    <name>W6ZTE3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_652</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682648.1">
        <property type="nucleotide sequence ID" value="XM_007684458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTE3"/>
    <dbReference type="STRING" id="930090.W6ZTE3"/>
    <dbReference type="GeneID" id="19124985"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_652"/>
    <dbReference type="eggNOG" id="KOG0590">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_82_1_1"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000595">
        <property type="entry name" value="Protein kinase, putative (AFU_orthologue AFUA_5G11840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="403"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="622"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="747"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="347"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="658"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="671"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC50804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="769" mass="83582" checksum="78F001BFBB1F62A7" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTF7</accession>
    <name>W6ZTF7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_32016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682696.1">
        <property type="nucleotide sequence ID" value="XM_007684506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTF7"/>
    <dbReference type="GeneID" id="19122007"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32016"/>
    <dbReference type="HOGENOM" id="CLU_450540_0_0_1"/>
    <dbReference type="OrthoDB" id="3665856at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="606" mass="67691" checksum="420388A3F306D356" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTT9</accession>
    <name>W6ZTT9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_3857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686298.1">
        <property type="nucleotide sequence ID" value="XM_007688108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTT9"/>
    <dbReference type="STRING" id="930090.W6ZTT9"/>
    <dbReference type="GeneID" id="19123504"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3857"/>
    <dbReference type="eggNOG" id="KOG1726">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048918_0_0_1"/>
    <dbReference type="OrthoDB" id="434647at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF177">
        <property type="entry name" value="PROTEIN YOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="342" mass="38479" checksum="1F2E072797F85059" modified="2014-04-16" version="1">MFGFIADGLTVVTTVFFPIFASYKALHTSDPALLAPWLIYFVVLSACTAVENTFDFILSWVPFYSWIRFFAHLYLILPGAQGASYIYQEHLEPFLYHHEKEIDDFITQSHDRAKSAGMAYIEMGIEWVRVNLLGFAPRKPEAPPPAGQTYAQSLMSRFQMPAARGSNDLYGLVNQALSGASALYTAGTPETRDAQASDLSRGAAKLVPDSIRNNEDRLNYVASQRQRLESLLQAFDREQENIRTQQKGGNTHYESSRSSGSLSRNRSEAEFDRIERDELSSGSDRPPYPITPPALGRRTSSGWMPWNWQRQEASQDDPLAYGRDPGELRNRSRGSGFDLGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVI8</accession>
    <name>W6ZVI8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GPI-anchored wall transfer protein</fullName>
            <ecNumber evidence="9">2.3.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_34688</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">A acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Endoplasmic reticulum membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the PIGW family.</text>
    </comment>
    <dbReference type="EC" id="2.3.-.-" evidence="9"/>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685670.1">
        <property type="nucleotide sequence ID" value="XM_007687480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZVI8"/>
    <dbReference type="STRING" id="930090.W6ZVI8"/>
    <dbReference type="GeneID" id="19122615"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34688"/>
    <dbReference type="eggNOG" id="KOG0411">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020802_2_2_1"/>
    <dbReference type="OrthoDB" id="15270at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032216">
        <property type="term" value="F:glucosaminyl-phosphatidylinositol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009447">
        <property type="entry name" value="PIGW/GWT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06423">
        <property type="entry name" value="GWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017321">
        <property type="entry name" value="GWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 9" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU280819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="489" mass="54019" checksum="5583528B5DC21FEA" modified="2014-04-16" version="1">MAKTYKQMKEAWVSGHTGSSVADVNIVSLAMPLSILLWSVIQSRMRLFTPYTPAALFIDFLLNCGATLFATTIYSPSPLILNLLLLLPAITLYVLEKPAPAKEAPRPPKIDKSEKDSKLDALPVKPFITNYRGAMMVITCVAILAVDFRVFPRRFAKVENWGTSLMDMGVGSFVFTAGVVSVRSSLKQGTGRPPLSKRLTASFRHAIPLLVLGVIRLISVKGLDYAEHVTEYGVHWNFFFTLGFLPPFAALFQSAFDLVPSYAVLSFVLAAVYEVVLDWTSLGPYILVAPRTDLLSKNREGIFSFFGYLAIFLAGQSLGASALPRQQPIAKDAPMTTKLRQSTLGKLATTSLVWTALFYFSTSYYGLRLSVSRRLANLPYFLWVSSFNSYQITICCAIETVLFPSLYKATNKSEELRRTRDATSTILYAFNRNGLVVFLVANLLTGLVNMTLPTLNMSIIESMTVLIAYIAVVAGVAVVLDHYNVTIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZW92</accession>
    <name>W6ZW92_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_34488</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic ribosomal protein eS4 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC48096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_eS4_C"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_eS4_central_region"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_eS4_central_sf"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_eS4_KOW"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_eS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018199">
        <property type="entry name" value="Ribosomal_eS4_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="PRK04313.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16121">
        <property type="entry name" value="40S_S4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00900">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RIBOSOMAL_S4E"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein eS4 N-terminal" evidence="11">
        <location>
            <begin position="3"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="10">
        <location>
            <begin position="43"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Small ribosomal subunit protein eS4 central region" evidence="9">
        <location>
            <begin position="95"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="180"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Small ribosomal subunit protein eS4 C-terminal" evidence="12">
        <location>
            <begin position="212"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC48096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="262" mass="29382" checksum="38CB7AFC54BD63D0" modified="2014-04-16" version="1">MARGPVKHQKRLSAPSHWLLDKLSGAYAPKASPGPHKLRDSLPLVIFLRNRLKYALNAREVNAILMQRLVKVDGKVRTDSTFPTGLMDVISIEKTGENFRLIYDTKGRFTVHRITDEEAQYKLGKVKRVQLGKGGIPYLVTHDARTIRYPDPAIKVNDTVKVDLSTGKISDFIKFDTGVIVMVTGGRNMGRVGVITHRERHDGGFNIVHLKDAVDNEFTTRESNVIIIGKEKPWISLPKGKGVKLSIAEERDRRRAYALAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYR7</accession>
    <name>W6ZYR7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_2296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684587.1">
        <property type="nucleotide sequence ID" value="XM_007686397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYR7"/>
    <dbReference type="STRING" id="930090.W6ZYR7"/>
    <dbReference type="GeneID" id="19120352"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2296"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_044629_0_0_1"/>
    <dbReference type="OrthoDB" id="441812at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF76">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="30"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="475" mass="53740" checksum="9032FDEABDF20533" modified="2014-04-16" version="1">MIRRGRSEGWLKQPIDALPTWATFNGVTFDKVKIGPLPGHEDRGSTVIADQNLQGGNVDPLIVVPKELIISRQNIDLLAKSDHRLHDLLEALGDFGRTTRGAVLSFLLLQATICCPDTKDVGLLNPLTQYIKFLPDELLPTFWTEEERELLVGTTLKPAVSAKLNSLLREFENLRTATESIPWCNKYWWDEEDGMLTFDDWMRVDAMYRSRALEFPGAGDCMMPCVDMANHASGNATAALYETDSNGNGLLLLREGQNIEAGGEVTITYGDDKGACEKIFSYGFLEDGMTSAKVMFLDLDIPDDDPLRPAKIYVSTEAPGFRIFEKDGEIDWEGDFIWLVVVNEEDGLDFKVRQTTDGKKSIQGFWRESELDTSKLRKYLEEDATWEVFQLRATVLLQARIDEQIEALRGAEGIKREGTIRELPWKLAERLRSLELEMLQRAASVFDKQRAKLLDSPTVIHYLGMDEQEEEVDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0B9</accession>
    <name>W7A0B9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_84454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684007.1">
        <property type="nucleotide sequence ID" value="XM_007685817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0B9"/>
    <dbReference type="GeneID" id="19126467"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84454"/>
    <dbReference type="eggNOG" id="ENOG502R87N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2812868_0_0_1"/>
    <dbReference type="OrthoDB" id="3707219at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="63" mass="6640" checksum="1898B5BD1A038938" modified="2014-04-16" version="1">MPAAAKSYLPAFAAFMAFGLTYTTVVASKEGAAVDGARTRWQQQHARARYALSGGMAALSESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W7A2S3</accession>
    <name>W7A2S3_COCMI</name>
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        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_22177</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A2S3"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_22177"/>
    <dbReference type="eggNOG" id="KOG3098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030884_1_2_1"/>
    <dbReference type="OrthoDB" id="196103at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF54">
        <property type="entry name" value="DUF895 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_8G04110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="432"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC50301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="54930" checksum="56BED6BEF8B26BF3" modified="2014-04-16" version="1">MATSTDKDNLAHHVNSADHSLTDSTALDLPKSWKYRRFTIAGFKLPWFASPPTQLVIVSFVCFMCPGMFNALNGMGGGGQLDPTANNRANTALYSTFAVIGFFAGTFTNKLGIRTSLSFGGIGYSVYVGSYLCYNHTQNLGFTTFAGALLGGAIMMSYPPEASKGRYISWFWMIFNLGAVIGSLIPLGQNIHTKTAGTVNDGTYVGFLVLTILGAALAWTLVDARDVIRDDGSKVIVMKHPSWKSEISGLWQTFFTDPYIILLFPMFLASNWFYTYHFTQINAAYFNVRTRALNGVVYYIMQIIGAYIFGYGLDVKGVRRTTRAKAAWAALFISVMLIWGFGYMFQKTYDRAWAENENNMKKDWSDAGYAGPFVLYMFYGFFDAAWQTCVYWFMGALTNNSRKLANFAGFYKGIQSAGGAITWRLDDLKVSYMAMFASNWGLLAGSLLVALPVILWKVEDTTAVEKDIEFTDETVADVLPHAHTESAHIEPEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W7A561</accession>
    <name>W7A561_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_21232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682084.1">
        <property type="nucleotide sequence ID" value="XM_007683894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A561"/>
    <dbReference type="GeneID" id="19120023"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21232"/>
    <dbReference type="eggNOG" id="ENOG502SMN6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_4_0_1"/>
    <dbReference type="OrthoDB" id="5405781at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF128">
        <property type="entry name" value="ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="1"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="424" mass="47698" checksum="64CF7B1D07F68B8E" modified="2014-04-16" version="1">MVVCGHLCTAFVPWLHQPAADAKTAPHLFQLPFFRLAVGGRSAVAIFFLVTGYVNSIGAISKSRAGNHEAAFHGIARSALARSGRLILPTMIATVISWFLAQTNAYHMTKHVDAQWIRQGWHRQEPSLWMALKSLFKAQTETWVIGWDEYDGTQWTLHLFLEGAFLVYTTMFATVLVRPKARFLIYAILYAYFWQVGKELTVGSIKGLNIVFGMFVAELHNHYKDSATSVLPAPIPAMLIVFGMFMAGFPQDSFQNAHWSETMATIMHTLTAEKTDIRRYWDHLGAATILLGIFFSKNARKVLTSPVFNFLGRVSFPVYLIHNTLIKTVLTWMIYLPSAMNPPKNEKGEMQDLQRGSIPHILIAIAVFYYILYRCASLWVKYVDPICANLTNAATKWAYGESQPKEIRPILANGATTDKSVLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNV5</accession>
    <name>W6YNV5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_107103</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964121">
        <property type="protein sequence ID" value="EUC41072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692403.1">
        <property type="nucleotide sequence ID" value="XM_007694213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNV5"/>
    <dbReference type="GeneID" id="19118982"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107103"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="466"/>
        </location>
    </feature>
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        <location>
            <begin position="53"/>
            <end position="473"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="507" mass="56055" checksum="E228DFDC66538FE4" modified="2014-04-16" version="1">MNKVDRDIDKLSCTNHIESSGKADTVIESYRSYTPEFAKEIEKQLVRKIDRRLLPLVVIIYLFNYLDRNSITQARLYGLQEDTHVTGALYQTAISIFSAGYIAMQLPATILMTKLRPSLYLPSCIITWAIVSGCTGATSSAGGLLAVRFFLGLVEAPFFPGAVYLLSCWYTKRELGVRIALLICGLLLSNSFAGLISAGILSGMKHVGKLATWRWLFILEGLATIVVGLCAMIFLPDYPATTKWLSEDEKIVAQGRLAADAGSESTLGEEDVKIWSGIVLASKDVRVWLFACLQMAVTASISYSHFFPTLIKQIGFKNNTTVLLLTSPPYLFAFIWALSFAVVADKKQNRSIGAGISAVVAMLGSILMMTILDNHWARYGFTFLVCVGTFGVFSTTYTWLSSTIPRPPIKRAAAIGIANTCANTASLFANYFWLDQYQPVFTVSWGCTLAFQTLAFSSILALCFLLRRGNKKFERLARTTDRNDADAIARLDDDSQRAILNGFRYIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPN7</accession>
    <name>W6YPN7_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_111435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964393">
        <property type="protein sequence ID" value="EUC39488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPN7"/>
    <dbReference type="GeneID" id="19119772"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111435"/>
    <dbReference type="HOGENOM" id="CLU_3001891_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="57" mass="6162" checksum="CF1C391AE27B12E1" modified="2014-04-16" version="1" fragment="single">GLNVGTVSGKAAFSSSFKPRLIEALIDTISCNPFIVKCSLVLIIFTTDLKRRKSASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPU6</accession>
    <name>W6YPU6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LNS2/PITP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_106303</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lipin family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC41397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692099.1">
        <property type="nucleotide sequence ID" value="XM_007693909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPU6"/>
    <dbReference type="STRING" id="930090.W6YPU6"/>
    <dbReference type="GeneID" id="19118836"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106303"/>
    <dbReference type="eggNOG" id="KOG2116">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002546_3_0_1"/>
    <dbReference type="OrthoDB" id="4567at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000063">
        <property type="entry name" value="Nuclear elongation and deformation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026058">
        <property type="entry name" value="LIPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007651">
        <property type="entry name" value="Lipin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013209">
        <property type="entry name" value="LNS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031315">
        <property type="entry name" value="LNS2/PITP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057124">
        <property type="entry name" value="Ned1-like_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181">
        <property type="entry name" value="LIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181:SF12">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04571">
        <property type="entry name" value="Lipin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08235">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24565">
        <property type="entry name" value="Ned1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00775">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LNS2/PITP" evidence="4">
        <location>
            <begin position="425"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="635"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="701"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="330"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="635"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC41397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="745" mass="82134" checksum="FE2B9F9117EAC627" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ80</accession>
    <name>W6YQ80_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_105806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964096">
        <property type="protein sequence ID" value="EUC41577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691911.1">
        <property type="nucleotide sequence ID" value="XM_007693721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ80"/>
    <dbReference type="GeneID" id="19118750"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105806"/>
    <dbReference type="HOGENOM" id="CLU_3142787_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="49" mass="5452" checksum="05A25ECE4E4DD594" modified="2014-04-16" version="1">MTNDSCLSFGEALLLYTAHAVKPPLPAPRFSSLWPGSNIFSRWKINIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ93</accession>
    <name>W6YQ93_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PQ loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_105748</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964095">
        <property type="protein sequence ID" value="EUC41597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691887.1">
        <property type="nucleotide sequence ID" value="XM_007693697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ93"/>
    <dbReference type="GeneID" id="19118742"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105748"/>
    <dbReference type="eggNOG" id="KOG2913">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040201_2_1_1"/>
    <dbReference type="OrthoDB" id="407617at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF37">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="32839" checksum="5D9B9B076E770EB6" modified="2014-04-16" version="1">MAPQTSIPLAANVLGTLGTVFWCVQLVPQIWRNYRTKSTVGLPESMMLLWSISGVPFGAYAIAQQFNIPLIVQPQCFGVLCGVSWAQCLIYGRKWRTWTASVLLCTLLVIFAGVEVGLVFAIRPPYSRGLEWPVLLIGIIAFLTLISGYLPIPFELLKRRGRVVGIDFIFLAIDWNGAFFSLMALVAQNEFDALFGTMYALCCAIEMSMVVSHLVWLFRTRDIRRRAKEAGKTFDKYEEGIEWQSKGFDVERLLKGICAGKNKGEEDGRSAAVDDIEASAAPEEVMPKTVPNATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS65</accession>
    <name>W6YS65_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_103885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964066">
        <property type="protein sequence ID" value="EUC42287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691180.1">
        <property type="nucleotide sequence ID" value="XM_007692990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS65"/>
    <dbReference type="GeneID" id="19118396"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103885"/>
    <dbReference type="eggNOG" id="ENOG502SA5Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095023_2_0_1"/>
    <dbReference type="OrthoDB" id="2151417at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849:SF1">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889366" description="Small secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="17872" checksum="0964F79118AFF5A9" modified="2014-04-16" version="1">MYFAPLAILSLSALSFAAPVVVPRQAGPVLKDTTYNAISISGGQAGNAKAEASALFSALDLQNPENIDQADLTFLNEVNQVANDAETKAFNPAVEAASGTEATQIQNGKIKNKVLKLMATVIKLQAQQAQGDDVAAKLAEETKKLNTNVALDTAAAGQVSIAEPFDAKISGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSB4</accession>
    <name>W6YSB4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF336-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_103784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964065">
        <property type="protein sequence ID" value="EUC42327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691165.1">
        <property type="nucleotide sequence ID" value="XM_007692975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSB4"/>
    <dbReference type="GeneID" id="19118376"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103784"/>
    <dbReference type="eggNOG" id="ENOG502SMVS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103773_2_0_1"/>
    <dbReference type="OrthoDB" id="2276076at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="entry name" value="Haem-degrading domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052517">
        <property type="entry name" value="GlcG_carb_metab_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34309:SF1">
        <property type="entry name" value="PROTEIN GLCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34309">
        <property type="entry name" value="SLR1406 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="HbpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="GlcG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="15240" checksum="CA46DC223BBE1F7D" modified="2014-04-16" version="1">MSTKEVPTLTLAGARVALEAAEARAKEINVPMNIAIVDNACHLLAFARMEGAKFTSINTAIDKAFTAAGHRAPTSIYKDVVWPGGPAFGINHSNGGRFMTIAGGVPIKKDGAVVGAIGCSTGTPSQDEDVASKGVEAVEKSFGIKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU04</accession>
    <name>W6YU04_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS9m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">37S ribosomal protein S9, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_9212</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964125">
        <property type="protein sequence ID" value="EUC41003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692468.1">
        <property type="nucleotide sequence ID" value="XM_007694278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU04"/>
    <dbReference type="STRING" id="930090.W6YU04"/>
    <dbReference type="GeneID" id="19128015"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9212"/>
    <dbReference type="eggNOG" id="KOG1697">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036531_2_0_1"/>
    <dbReference type="OrthoDB" id="10254627at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_uS9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001099">
        <property type="entry name" value="PRK00132.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="330" mass="37017" checksum="E2BF2A1933C05957" modified="2014-04-16" version="1">MASRELSRSMWRAFDALGSRPLPQCQRAIRPVQRSLHPQIRRCISTTAARHAEVTEDELRQPFKAAPEFDFEGISGSGEEGEKKNILRTLRVVPASPSYFSAKPTFTDDFLSLSALLRKVATLPTISPAEAPKVAWKTIEQYRIMTNEPVKTARYHRMLQILRRLNCIHPSLMPEEVLQAMQRYKKPVQPGDIKPKPGVIDELGRAKGVGRRKTSSAVAWLVEGEGEVLVNGKSLSQFFGRLHHRESAVWALKATQRLDKYNVFALVQGGGLTGQAEAMTLAVAKSLLVHEPALKPALRRAGTITRDPRKVERKKPGHVKARKMPTWVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU14</accession>
    <name>W6YU14_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_102179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964044">
        <property type="protein sequence ID" value="EUC42952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690549.1">
        <property type="nucleotide sequence ID" value="XM_007692359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU14"/>
    <dbReference type="GeneID" id="19118025"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102179"/>
    <dbReference type="eggNOG" id="ENOG502T6AR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_415602_0_0_1"/>
    <dbReference type="OrthoDB" id="3937441at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="660" mass="73914" checksum="2E48FE0F9784FD9B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUI6</accession>
    <name>W6YUI6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Small nuclear ribonucleoprotein E</fullName>
            <shortName evidence="11">snRNP-E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Sm protein E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_38918</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690363.1">
        <property type="nucleotide sequence ID" value="XM_007692173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUI6"/>
    <dbReference type="STRING" id="930090.W6YUI6"/>
    <dbReference type="GeneID" id="19123580"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38918"/>
    <dbReference type="eggNOG" id="KOG1774">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125186_1_1_1"/>
    <dbReference type="OrthoDB" id="25620at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990935">
        <property type="term" value="F:splicing factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036261">
        <property type="term" value="P:7-methylguanosine cap hypermethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01718">
        <property type="entry name" value="Sm_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000031">
        <property type="entry name" value="Small nuclear ribonucleoprotein E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027078">
        <property type="entry name" value="snRNP-E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11193">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="17"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC43127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="94" mass="10540" checksum="D66D5CA46E3BB581" modified="2014-04-16" version="1">MTGRGGRGGGKVLLPPINFIFKLLQSRATISVWLYENLGMRIEGKLRGFDEFMNLVIDDAIEVTLAKKDAPEERRKVGQILLKGDNISLIQQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV66</accession>
    <name>W6YV66_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Geranylgeranyl pyrophosphate synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_8863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964103">
        <property type="protein sequence ID" value="EUC41435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692051.1">
        <property type="nucleotide sequence ID" value="XM_007693861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV66"/>
    <dbReference type="STRING" id="930090.W6YV66"/>
    <dbReference type="GeneID" id="19127317"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8863"/>
    <dbReference type="eggNOG" id="ENOG502QRQN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030046_1_0_1"/>
    <dbReference type="OrthoDB" id="5393654at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF2">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="57251" checksum="C268010C9669A1E3" modified="2014-04-16" version="1">MNPFTGTSSRGGFAPRRGQGQGGRYPYFNKVREQPKPDFTKRPLGDLFHTISASDLDVGANTTSHSTEISGCEYVASYNWTNETSPTIVVPGKPPKWTPLTEPQRLKEDSGQYFRDLNAAKNPSYPMAPAVNAVLEQDYRYRTDDIDIFACGSTLGNLLRFARGVDKPFRFNLQVINRTVFLVRKENDPKELIEGVRGYGHTFPEAYTTWEDDVKNSISHQRIICYKFGGLTHLLRFESDGYILDLLPEDTTPPPRSGPNEDNNNNTNAKNEDKEKNASPEKHLIHSLQALTIQAPTIIPSTSTIPPHTTLFDLKTRSAKNFKKIDMTDILPQLWLKRIPNFITAYHDGHGLFTDISVRNVEPDVQDWAVENSTGIEKFAVLLRELVRIAREKSHSGTDVLMEVYCPGKEKLEVRMQAAEGQEALPWWLRERWEGNGKEEGKGRADSPVENGLDDDDDDEEEEEQEDFVGVSRRYDSYYGSEYDSGSEPDYTACSADDCGYCGKCSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW32</accession>
    <name>W6YW32_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PEBP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_105369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964088">
        <property type="protein sequence ID" value="EUC41748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691740.1">
        <property type="nucleotide sequence ID" value="XM_007693550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW32"/>
    <dbReference type="STRING" id="930090.W6YW32"/>
    <dbReference type="GeneID" id="19118674"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105369"/>
    <dbReference type="eggNOG" id="ENOG502S6VR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043994_4_4_1"/>
    <dbReference type="OrthoDB" id="2506647at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030162">
        <property type="term" value="P:regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046578">
        <property type="term" value="P:regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF148">
        <property type="entry name" value="CARBOXYPEPTIDASE Y INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889283" description="PEBP-like protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="24306" checksum="68C0DF6B93D68696" modified="2014-04-16" version="1">MKTTFLSAAALLLSTTAADVAPAFPLPGGPTNLTITYNNNDTVSPQGELLPRPVTAQPPSLSAPKLTPASNSNLYILLMIDIDVPRNSTRVPLIHWLAPNISLSSPSSSLIIPSPNPVPYLQPSPPVGDIPHAYNFVLFEQPAGFQVPARYAELAGMRVGFDVRQFVGEAGLGGVVASGWLRVQNLTGVAGPTGTGSGARPSQTGGYTGPESNEGGKVVLGWMGVAGALAVAVGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWI9</accession>
    <name>W6YWI9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_29374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964080">
        <property type="protein sequence ID" value="EUC41925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691549.1">
        <property type="nucleotide sequence ID" value="XM_007693359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWI9"/>
    <dbReference type="GeneID" id="19121493"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29374"/>
    <dbReference type="HOGENOM" id="CLU_1434226_0_0_1"/>
    <dbReference type="OrthoDB" id="10415171at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="189" mass="21000" checksum="9F4952BFBB7D0F62" modified="2014-04-16" version="1">MAVETDHGPVIVYPSSAAVPRQAVDWAYDYDSQCNVSTNPCNVRTTDVMTAVYGFSSVMSKVLGRLNKDDVVFKRRIAAVEIESHRERVLSSAHVVVPDLRKEWKQATAHFVEITQWRPPGNASRGKRRQATNAMSRAKWAGQEAAAAGAGTGICIGRDSTVEIFWHMDGDCYFAQFQAMWTSKSTDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXH0</accession>
    <name>W6YXH0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_99009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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    </evidence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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    <accession>W6YY59</accession>
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            <fullName evidence="4">PI-PLC Y-box domain-containing protein</fullName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
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            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1208"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1270"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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        </location>
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        <location>
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            <end position="360"/>
        </location>
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    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="859"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="872"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="923"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1122"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1219"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1272"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1308"/>
            <end position="1348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1355" mass="144418" checksum="2780E823AC75DBA3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY67</accession>
    <name>W6YY67_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Casein kinase II subunit alpha</fullName>
            <shortName evidence="10">CK II alpha</shortName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_98532</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="KI964007">
        <property type="protein sequence ID" value="EUC44277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689192.1">
        <property type="nucleotide sequence ID" value="XM_007691002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY67"/>
    <dbReference type="STRING" id="930090.W6YY67"/>
    <dbReference type="GeneID" id="19129283"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98532"/>
    <dbReference type="eggNOG" id="KOG0668">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_70_4_1"/>
    <dbReference type="OrthoDB" id="10254671at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006356">
        <property type="term" value="P:regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006359">
        <property type="term" value="P:regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000059">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000088">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="43"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC44277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="342" mass="39915" checksum="5B21A4D473B188A7" modified="2014-04-16" version="1">MALNNSSGATSIARVYADVNANMPRSYWDYDSVNISWGVLENYEVVRKIGRGKYSEVFEGINVVNYQKCVIKVLKPVKKKKIKREIKILQNLSGGPNIVSLLDVVRDNQSKTPSLIFEYVNNTDFRSLYPKFQDFDVRFYIFELLKALDFCHSKGIMHRDVKPHNVMIDHEKRKLRLIDWGLAEFYHAGTEYNVRVASRYFKGPELLVDFQEYDYSLDMWSLGAMFASMIFRREPFFHGNSNSDQLVKIAKVLGTEDLFDYLDKYDIELDAQYDDILSRYPKKPWHSFINAENQRFVSNDAIDFLDKLLRYDHQERLTAQEAMSHPYFAPVRQAAQQNSTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYB2</accession>
    <name>W6YYB2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_9598</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <dbReference type="EMBL" id="KI964156">
        <property type="protein sequence ID" value="EUC40549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692934.1">
        <property type="nucleotide sequence ID" value="XM_007694744.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6YYB2"/>
    <dbReference type="GeneID" id="19128763"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9598"/>
    <dbReference type="eggNOG" id="KOG0293">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005921_0_0_1"/>
    <dbReference type="OrthoDB" id="972532at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
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    <name>W6YZG5_COCMI</name>
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        <recommendedName>
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="eggNOG" id="KOG0692">
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089:SF1">
        <property type="entry name" value="BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="SHIKIMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="1">
        <location>
            <begin position="22"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="313" mass="34632" checksum="281F2FEE91837039" modified="2014-04-16" version="1">MSTESTETRIPDVSQTERHGYLFGYPIAHSMSPLLHQTVYDGLGLNWSQYPLESKDMSLFLQLIKHPQFYGASVTMPHKVAILPHLDGLTEEGRDVGAVNTLFIQEDPSTGKRLYMGTNTDVIGIRDAFAYNVDASKYENRPALVIGGGGAARSAVYALRKWMKASAIYLVNRDASEVSAVISECSTRGYGSSLVHVSSLSQAQSLPGVGAIVSCVPNFSPVSPQEHEARDILNCFLQKEHKGALLEMCYHPTTWTEIAEIGKNEGWQIVLGTEALIYQGLEQDRYWTAREVRELPVDKVQEAIARKLSEARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZH5</accession>
    <name>W6YZH5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964130">
        <property type="protein sequence ID" value="EUC40939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692554.1">
        <property type="nucleotide sequence ID" value="XM_007694364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZH5"/>
    <dbReference type="GeneID" id="19121640"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30222"/>
    <dbReference type="eggNOG" id="ENOG502S8NQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_374304_0_0_1"/>
    <dbReference type="OrthoDB" id="10249419at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07262">
        <property type="entry name" value="VOC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35006:SF3">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G06020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35006">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="2"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="773" mass="82810" checksum="B21D26F046D77496" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZR0</accession>
    <name>W6YZR0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_9181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964123">
        <property type="protein sequence ID" value="EUC41034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692429.1">
        <property type="nucleotide sequence ID" value="XM_007694239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZR0"/>
    <dbReference type="STRING" id="930090.W6YZR0"/>
    <dbReference type="GeneID" id="19127954"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9181"/>
    <dbReference type="eggNOG" id="ENOG502S09K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062649_0_0_1"/>
    <dbReference type="OrthoDB" id="5194044at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018811">
        <property type="entry name" value="MRX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28002">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28002:SF1">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="247" mass="28137" checksum="F7AC5FA10F9F1614" modified="2014-04-16" version="1">MEAYPKPRHQYIYTPRYGQRGILTYAGQAPNGAAPTGVIGGAYAYGVGYPATAAAVAATAYQPVVYNTRPFYGPNYLYPYYNPGYAYYNSYLYGSLYPLANFYFPYQRSYYNVVPSYGSTAHVYPPGHATTTTTTYHVTNAQAPLYASPTAQLLRETRPAYAHGHAYTPQAPTREDIQFENRRIATQRGAYDARKIRPADARDDDPFWCREVNGEWHLRSYYQIENECHPGRWMMDAEIGFLVFHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZW5</accession>
    <name>W6YZW5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690358.1">
        <property type="nucleotide sequence ID" value="XM_007692168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZW5"/>
    <dbReference type="GeneID" id="19121297"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28390"/>
    <dbReference type="HOGENOM" id="CLU_1488755_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="181" mass="18648" checksum="3891B25DEFF4D935" modified="2014-04-16" version="1">MSNAQTQAQTLTRKPITAQRSAQRSAAPTDLAMSRQKQGRLWSSSAYHASSSLQPATHCRTSKTLGATDDGGGHGGGEDGRGEKGDKIQMNSNANDDDSDDDDNNGGGGGIGRGGSDGNNTAVAWVWGRQESQTEGGQKLLLAISSPPSVAHNAHCQTTFDSACIALESTPGTPSAKPPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZZ4</accession>
    <name>W6YZZ4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_5787</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <location>
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            <end position="109"/>
        </location>
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        </location>
    </feature>
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        </location>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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        </location>
    </feature>
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            <end position="283"/>
        </location>
    </feature>
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        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="757" mass="82999" checksum="2CFB7DEF30E35F39" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
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    <name>W6Z1K0_COCMI</name>
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        </submittedName>
    </protein>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
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                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="HOGENOM" id="CLU_1695166_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="155" mass="16830" checksum="002A9674E0071F44" modified="2014-04-16" version="1">MRRGDRWQNLLLIARGPWRTCNTHWAEGVVPWVWVWSRGPAAAQQSSPAAQHTGTQAHRRCFCTQRPPPRGQSIPGTRGWETGDRRAGAAPAGLVCVTVLYAATATAWSPAIHPPRPSGSTLTRLTASSTVWQAGNVTQMRCQQARLVPAVSADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
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    <name>W6Z2H4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_40042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC41834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691649.1">
        <property type="nucleotide sequence ID" value="XM_007693459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2H4"/>
    <dbReference type="GeneID" id="19123799"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40042"/>
    <dbReference type="HOGENOM" id="CLU_128905_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886394" evidence="2">
        <location>
            <begin position="19"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="178" mass="16850" checksum="A2CFFDBDCA6AAE31" modified="2014-04-16" version="1">MFGSKILAVAALALSVVAHETTCPAPTTVTITVTHSITRPGPPPTPSSSYASPPPPAESVVAPSPSSVVSLTSAVTPHEPIPTSETAAPSGPAPSIAPSAPLESSPAASGATTVPIVVAPSAVVPPVSSTVEAPPASSSAVASSPALPEITNAAAIATPLGGLGSLLAIGAAALVAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3H4</accession>
    <name>W6Z3H4_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_93202</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502R21Q">
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    <dbReference type="OrthoDB" id="3792161at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="200" mass="22830" checksum="8564C183741D53AE" modified="2014-04-16" version="1">MLLTMKTTHPRANDLISLLWNWHLHKRETTLFRRLGMHSLEIVGLSTAMLIIPLSMHRAVQGFDEMYDILGRRAKSPYARLSWVNIALAFVVLVGWHMWLGRLTYLTVLESNIDEEKDEERNDEITALTSSAEKSNTGSGKGEISWGRILGRILIPLLLVTLGLHFGYQVCRQLITDTRPLITRNDVDMQEAMGQLYGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z411</accession>
    <name>W6Z411_COCMI</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_6080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z411"/>
    <dbReference type="STRING" id="930090.W6Z411"/>
    <dbReference type="GeneID" id="19124827"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6080"/>
    <dbReference type="HOGENOM" id="CLU_1294173_0_0_1"/>
    <dbReference type="OrthoDB" id="3695406at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="213" mass="24157" checksum="112E0CDADD1E31E7" modified="2014-04-16" version="1">MPQQVYHHGLPGQVHQVPQHAHQGLPQNLRHVPQQMYQTPQHIHPVPQPIHQAPHQVYQMPQQIHQIPQHMLQEPPQNVVPGSQQISKAQERPRQIPGLRGSPQQVPGLQQPQQLVPEPQQSQQDVVPEPQEIPEIQEPQASGDKELQVITNEPQPKVADKEPEKSSVDQEQTVQEPQKIDEVPQLPQKSQDSQKPEYTDDGSKDTEPESSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z760</accession>
    <name>W6Z760_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_94562</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687698.1">
        <property type="nucleotide sequence ID" value="XM_007689508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z760"/>
    <dbReference type="STRING" id="930090.W6Z760"/>
    <dbReference type="GeneID" id="19128472"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94562"/>
    <dbReference type="eggNOG" id="KOG3250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054426_0_1_1"/>
    <dbReference type="OrthoDB" id="10265275at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF5">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22061">
        <property type="entry name" value="CSN7_HB_subdom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="2"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC45820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="265" mass="29048" checksum="7A4C1B7912788FE0" modified="2014-04-16" version="1">MEQTKALNALEPFLALSKSATSPRAASDLIVQATSAPNTYVFAELLQTPNIQNLRTSEEYGPYLTLLEVFAWGTWADYKAQPNLPKLSAQQHQKLLLLSLLPLSHSHTTLTYKHLMTSLELPTPRALEELITTAIYSGLITATLDPAHSLVSVTSISPLRDLAPGSLPALQNTLQSWSQRCDSALADLEAQAAKVKQEALDREKLRRKKERAFEAAMQATDEKNNGKRNLMGDDAMEIDDEGGSGRVTRGNKRGSAGFGLHLGRR</sequence>
</entry>
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            <fullName evidence="5">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="35"/>
        </location>
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        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
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        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="60215" checksum="D5322EC74C25AF70" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z794</accession>
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        </submittedName>
    </protein>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="OrthoDB" id="3440281at2759"/>
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    </dbReference>
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        <location>
            <begin position="163"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="193" mass="21859" checksum="487CBB302E15A475" modified="2014-04-16" version="1">MADLRDIDIRFAREFNSAKALHDNELLDDCVESARELLEDPVVPRFHRMKTLLLLGSALEDLNEACDCLEEADKLWKLIRSYHLEGQDVDVDKTMAEVRASLDQLAKALKNEEAEEYDLEDYVEIIANTDECQVADIQEMICGMEMEDDLDIDMDSNVEDVAAGRASQVQVEPVKEPLPSTDKVESLDTAQHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7B6</accession>
    <name>W6Z7B6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_100796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964028">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7B6"/>
    <dbReference type="GeneID" id="19117748"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_100796"/>
    <dbReference type="eggNOG" id="KOG4498">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035338_0_0_1"/>
    <dbReference type="OrthoDB" id="40334at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02970">
        <property type="entry name" value="PRX_like2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000404">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032801">
        <property type="entry name" value="PXL2A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630:SF3">
        <property type="entry name" value="PEROXIREDOXIN-LIKE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
        <property type="entry name" value="AhpC-TSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="342"/>
        </location>
    </feature>
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        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="37563" checksum="0311899A02BA424B" modified="2014-04-16" version="1">METSEAKATAPVPPPIMTSTPQPPATQVPSPPHSQSGHGAYAKPSMDVAENTTPPFSPSSQTPVLGGEQEEFEGTLDVNNDIPTEKELSAVADMLVLDAQGQSRPFKELYQAPHVASRQLIIFIRHFFCGNCQEYLRTLASSITPDDLLALPTPTFITVIGCGRPELIPMYTETTGCPFPIYADPTRKLYDHLGMTRTLNLGAKPQYMQTNVLINSVQSIFQGLSTGRKALKGGDFKQVGGEFLFENGECTWAHRMKTTRGHAEVSEIRSLIGLDSTRPPVRRRWSHEVKGPEKNRRRTVSWGRLRSKSKSGKDVSVSSSKQTTPDRILEEENEAPTGSSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7C7</accession>
    <name>W6Z7C7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_94204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963975">
        <property type="protein sequence ID" value="EUC45890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687581.1">
        <property type="nucleotide sequence ID" value="XM_007689391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7C7"/>
    <dbReference type="GeneID" id="19128410"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94204"/>
    <dbReference type="eggNOG" id="ENOG502SGJJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_404893_0_0_1"/>
    <dbReference type="OrthoDB" id="5329403at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="72"/>
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</entry>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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        </source>
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    </dbReference>
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            <end position="180"/>
        </location>
    </feature>
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            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC46330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="271" mass="30713" checksum="375BFD4718730471" modified="2014-04-16" version="1" fragment="single">NIQLVREWLQICKTSHKHDLAGPRGKECVPGFKVIDCRTKRIVPVRHDVCQYVALSYVWGAAAAEEHKEGQYPKTIEDSIAACNMLGFEYLWVDRYCINQNDEAEKGIQINMMDSIYAQAQLTIVATDPNPSKGLPGIGSRVRNKQQSLRLGNIELIKTYHTDEAILRSTWATRGWTFQEGYLSRRKLIFTENEAVYVCDDMYCQESIRRDIPTRSTGQHQGLAGAAMDGICPMSTNERKGRVKLDDLLNEYNSRDLSYQSDALNACQGIL</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
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        </source>
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    </dbReference>
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    </feature>
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    <sequence length="528" mass="57541" checksum="86A6E4DCD4BAFCB9" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="15925" checksum="51F3AB9DACFD54E1" modified="2014-04-16" version="1">MPPQNQNNGDSHIFLLPTLPLTLALVAPRHPPSPHLHSPPDCAPTTTITKTVTVTIPIYAPTGNISVPFPNATVTATSTGTGGLEPITLITLSSAAGEVTVTATATGGGLEPITLITLPTATATALESAGDGGDGGAVGAAPTPNDIAPITLIDISTATPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
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                <person name="Han J."/>
                <person name="Copeland A."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NUCLEOLAR RNA-ASSOCIATED PROTEIN"/>
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    </dbReference>
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        <property type="entry name" value="Nrap"/>
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    </dbReference>
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    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
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        <location>
            <begin position="228"/>
            <end position="373"/>
        </location>
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            <end position="519"/>
        </location>
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        <location>
            <begin position="525"/>
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        </location>
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        <location>
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        </location>
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            <begin position="1"/>
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            <begin position="40"/>
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    </feature>
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            <end position="101"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU364032"/>
        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF17403"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF17404"/>
        </source>
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            <dbReference type="Pfam" id="PF17405"/>
        </source>
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        <source>
            <dbReference type="Pfam" id="PF17406"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF17407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC48462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1207" mass="134976" checksum="FEF1E3C7B7B980B8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9Q2</accession>
    <name>W6Z9Q2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit DAM1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Outer kinetochore protein DAM1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_34159</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAM1 family.</text>
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    <dbReference type="OrthoDB" id="5586015at2759"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990758">
        <property type="term" value="P:mitotic sister chromatid biorientation"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28113:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAM1"/>
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    </dbReference>
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        <property type="entry name" value="DASH_Dam1"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
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            <end position="219"/>
        </location>
    </feature>
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        <location>
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            <end position="80"/>
        </location>
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            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
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            <end position="34"/>
        </location>
    </feature>
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        <location>
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            <end position="164"/>
        </location>
    </feature>
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            <end position="219"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC48477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="219" mass="23155" checksum="DFB09D9DE19A3455" modified="2014-04-16" version="1">MASTTPTTTPSYRRTRSKSPRSRPTTPLRPSSRSSLRDSSQRGRAASASNNALEGLQDGFAELSDAMADLEQNFVQLQLMHESLARFSESFAAFLYGMNMNAFCVDFPEAPIHESFKRPQNQPDGGAANLSRSQGPEDMEATFLTTDTSFVDNPPGSKTPSKPQTPAPAAKTSGLPRGRGGIPRAGGRGGIPTRGGTTRGTRGGTGIARGVAGRGRGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9S6</accession>
    <name>W6Z9S6_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_30616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964164">
        <property type="protein sequence ID" value="EUC40456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693030.1">
        <property type="nucleotide sequence ID" value="XM_007694840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9S6"/>
    <dbReference type="GeneID" id="19121704"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30616"/>
    <dbReference type="HOGENOM" id="CLU_1224568_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="226" mass="25805" checksum="52872E6FA06CEA6E" modified="2014-04-16" version="1">MARVVSCRLELPSSAMAAATRGRACSFHTHLYNKLHATWIRGRDCAPRSTLPGIHQMDKAPSERYFLDPPPSALACPLLLADWLLPSSATANLSRSEILACLMSVSRLQRRPQPWNPLHATRYSATPALRHFHLRPCHAMPCHVHCAFHPAMCPSCCTFPDYYHHYYHHYYHCYYYYYYYTLEVLLHPQPSAVHLSIVRHRISTPPACLPRPLSHRPSPSLLAAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAF6</accession>
    <name>W6ZAF6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_91350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC46970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686495.1">
        <property type="nucleotide sequence ID" value="XM_007688305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAF6"/>
    <dbReference type="GeneID" id="19127865"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91350"/>
    <dbReference type="eggNOG" id="ENOG502SIE8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_839388_0_0_1"/>
    <dbReference type="OrthoDB" id="3945961at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="37283" checksum="4ABB6E6A8BDC35B4" modified="2014-04-16" version="1">MGNGVQQPLEATDPRDKVFALLGLANDKDSLEALGVVPDYTKSKEEVYTTAMAAMLRKGHISLLSICCGMKRPNGLPSWVPDWSKADPPMFQVIGDDDYSLHPVFNACGSKNKHRFILPTKDPKPERILVYAKQVDEVFQLGHVGRLPSMPRAVSPVEWLDAMLQLTYCVDKPYLDVKERMRTTARASHAGMRIGENNMLQRASEFPEALTILEEVIQIGTKDDGFPESQNALRRALLNYRMTEYPSHMFQMLGEILRINDCKVPLITKEGRLGISSMTVKVGDLVVLVSGAQVPFILRRTDTRYMTVGEAYIDGIMDGEAAEDGEWIHIELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB75</accession>
    <name>W6ZB75_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_35200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963955">
        <property type="protein sequence ID" value="EUC47200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686248.1">
        <property type="nucleotide sequence ID" value="XM_007688058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB75"/>
    <dbReference type="STRING" id="930090.W6ZB75"/>
    <dbReference type="GeneID" id="19122730"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35200"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_1"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="11"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="331" mass="35393" checksum="65F82E5CC2BD69E1" modified="2014-04-16" version="1">MRAWQFKASSGPMEKNLSIPPSGLPIPSIKDDEVLVESYATGLNAIDYKVLELGLITRLVFPSVTPGLEIYGRVTKTGSKVSKFREGDIVFGSIGPGPKHGALAEYVPVSQDLLAKAAEGLKGDDLVAISLVGMTVHAGLAPYAKPGSKVFINGGSGGTGVAAVQMAKILGYEVTASCSTANIELVKSLGADHVLDYTTAPIIEQLKDRGEVFDLILDNVGAPANLYRASTPFLRAEGKFIQVGLGVSLSGALQLLGNNIASLFSWGKRGYVFVDAKPRTEVFEQLAEWMVEGKLRAVVDSTWEFGDVPKAYERLKTERARGKIVVHVKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBH4</accession>
    <name>W6ZBH4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_97278</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688697.1">
        <property type="nucleotide sequence ID" value="XM_007690507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBH4"/>
    <dbReference type="STRING" id="930090.W6ZBH4"/>
    <dbReference type="GeneID" id="19129028"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97278"/>
    <dbReference type="eggNOG" id="KOG1123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008213_0_0_1"/>
    <dbReference type="OrthoDB" id="10262986at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18029">
        <property type="entry name" value="DEXHc_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000077">
        <property type="entry name" value="Probable DNA repair helicase RAD25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000117">
        <property type="entry name" value="Putative DNA repair helicase rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="329"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="546"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC44799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="804" mass="90743" checksum="983B9000EAF297D5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC03</accession>
    <name>W6ZC03_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_90481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686203.1">
        <property type="nucleotide sequence ID" value="XM_007688013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC03"/>
    <dbReference type="STRING" id="930090.W6ZC03"/>
    <dbReference type="GeneID" id="19127693"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90481"/>
    <dbReference type="eggNOG" id="KOG2742">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_3_1_1"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF5">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="149"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="37180" checksum="9BBDD361EC957B8A" modified="2014-04-16" version="1">MAIGIALIGSGIFAKEEHLPAIQDAPVLSLKAVYSRSLKSAQSLSEKLSGVDLYSDDQDGKKFDDLLKRDDIKGVVIALPIPAQPDYIKKALAAGKHVFAEKPIAKDLSTASSLLAWTSNTSNTSATYTVAENFRFIDSYIWASQQLASLGRLLSFRVRVMFPVAVGSKYYETAWRKKPEHQGGFILDGGIHFVAATRLLLQGAGQKVKRVSAFTAQLQEHLPPVDTLNAVLQAENGSSGSLSISVGTTDQGSEYVVACEKGVVTVSRGKVVVKRQGEEKEEVKEFPDEGNGVKQEIKAWAKSLEEGKRNEMQSPEEALKDLEILESCLKSGEQGGTPIDVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC33</accession>
    <name>W6ZC33_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Electron transfer flavoprotein-ubiquinone oxidoreductase</fullName>
            <shortName evidence="19">ETF-QO</shortName>
            <ecNumber evidence="19">1.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">COCMIDRAFT_5754</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 19">Accepts electrons from ETF and reduces ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + oxidized [electron-transfer flavoprotein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24052"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.5.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="19">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="19">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ETF-QO/FixC family.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="19"/>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC44999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688465.1">
        <property type="nucleotide sequence ID" value="XM_007690275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC33"/>
    <dbReference type="STRING" id="930090.W6ZC33"/>
    <dbReference type="GeneID" id="19124728"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5754"/>
    <dbReference type="eggNOG" id="KOG2415">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009667_4_0_1"/>
    <dbReference type="OrthoDB" id="437331at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000015">
        <property type="entry name" value="Electron transfer flavoprotein-ubiquinone oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040156">
        <property type="entry name" value="ETF-QO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049398">
        <property type="entry name" value="ETF-QO/FixC_UQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007859">
        <property type="entry name" value="ETF-QO/FixX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617:SF107">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21162">
        <property type="entry name" value="ETFQO_UQ-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05187">
        <property type="entry name" value="Fer4_ETF_QO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 19" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 19" id="KW-0274">FAD</keyword>
    <keyword evidence="6 19" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13 19" id="KW-0408">Iron</keyword>
    <keyword evidence="14 19" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 19" id="KW-0813">Transport</keyword>
    <keyword evidence="15 19" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="20">
        <location>
            <begin position="589"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00052682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU366068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EUC44999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="629" mass="69704" checksum="4E41725EDA418B41" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCC7</accession>
    <name>W6ZCC7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bet v1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_33097</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683972.1">
        <property type="nucleotide sequence ID" value="XM_007685782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCC7"/>
    <dbReference type="GeneID" id="19122243"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33097"/>
    <dbReference type="eggNOG" id="ENOG502RXX9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124166_1_0_1"/>
    <dbReference type="OrthoDB" id="10255646at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39332">
        <property type="entry name" value="BLL4707 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39332:SF7">
        <property type="entry name" value="SRPBCC FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="16898" checksum="AE2B185935FB9E64" modified="2014-04-16" version="1">MSTIPTSTSVHESAVIEAPFSDVWHLIKLQDFSKFWTKLEKSEFVKGTSDETDIVKWTFKDGTELEVKQEEHSSIDHFITYSVITSKPELSYSSVVSTIRAYPVTSGKHQGQTFVTWSGNFSSDADASVIQDAKFKRREALADLAQAASKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCH5</accession>
    <name>W6ZCH5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_1760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683944.1">
        <property type="nucleotide sequence ID" value="XM_007685754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCH5"/>
    <dbReference type="STRING" id="930090.W6ZCH5"/>
    <dbReference type="GeneID" id="19119940"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1760"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025343_0_0_1"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF169">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="27"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="4">
        <location>
            <begin position="286"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC49512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="729" mass="78809" checksum="C1356B3EB768BBFF" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCJ4</accession>
    <name>W6ZCJ4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_84478</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684034.1">
        <property type="nucleotide sequence ID" value="XM_007685844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCJ4"/>
    <dbReference type="GeneID" id="19126472"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84478"/>
    <dbReference type="HOGENOM" id="CLU_3068295_0_0_1"/>
    <dbReference type="OrthoDB" id="10292126at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="53" mass="5825" checksum="BDA33245053271F3" modified="2014-04-16" version="1">MLSFSPSSEYISHVYETIDQHLGAGVQESIVRFLEDTLCDADASCRIVSLGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCL9</accession>
    <name>W6ZCL9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">glutaryl-CoA dehydrogenase (ETF)</fullName>
            <ecNumber evidence="11">1.3.8.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">COCMIDRAFT_1613</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13389"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:57378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid metabolism; lysine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid metabolism; tryptophan metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.6" evidence="11"/>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683828.1">
        <property type="nucleotide sequence ID" value="XM_007685638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCL9"/>
    <dbReference type="STRING" id="930090.W6ZCL9"/>
    <dbReference type="GeneID" id="19119905"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1613"/>
    <dbReference type="eggNOG" id="KOG0138">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_8_0_1"/>
    <dbReference type="OrthoDB" id="435240at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004361">
        <property type="term" value="F:glutaryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046949">
        <property type="term" value="P:fatty-acyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01151">
        <property type="entry name" value="GCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000003">
        <property type="entry name" value="glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000006">
        <property type="entry name" value="Glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000008">
        <property type="entry name" value="Glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052033">
        <property type="entry name" value="Glutaryl-CoA_DH_mitochondrial"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807:SF1">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="16">
        <location>
            <begin position="46"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="15">
        <location>
            <begin position="161"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="14">
        <location>
            <begin position="276"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EUC49567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="426" mass="46765" checksum="F7D8188557BA2F88" modified="2014-04-16" version="1">MLRPVYRHASRQLRTPVTFAATKKRNLHAPVAFDWQDPLKANDLLTEEEQAISETAESYCQERMLPRVLEAYRNEDFDRKIIQEMGELGLLGATIKGYECAGVSSVAAGLITRAVERVDSGYRSGYSVQSSLAMGGIEEFGSEELKERILPKMAKGQLLGCFGLTEPNHGSDPGSMETVAKEHPSKKGYYSLSGSKTWITNSPIADVLLVWAKLESTGKIRGFVIERDQCPPGTLETPPIKNKNGLRASITGMIQLDECPVPEANMFPEVEGLKGPFSCLNSARYGIAWGTIGALEDCIARARTYALERKQFKNNPIAKYQLVQKKLADATTDAAYGILAAHQVGRLKDEGKAAPEMISMIKRQNCDRALVNARTLQEIFGGNAVSDEYGIGRHVANLFVTQTYEGQSDIHSLILGRAITGLQAFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCR6</accession>
    <name>W6ZCR6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_96055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688243.1">
        <property type="nucleotide sequence ID" value="XM_007690053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCR6"/>
    <dbReference type="STRING" id="930090.W6ZCR6"/>
    <dbReference type="GeneID" id="19128778"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96055"/>
    <dbReference type="eggNOG" id="ENOG502SK2A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058481_1_0_1"/>
    <dbReference type="OrthoDB" id="1022638at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="18"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="310" mass="34838" checksum="30A89307B126E675" modified="2014-04-16" version="1">MSNVQEKPLNELLSRSMVDIYVGPENTHWILHEKLLCHHSPFFRKIFYSKSSTSSRTQSFGLPDEEDLPFKTFVGWLYSSSLPVPREEADLGTAFDLYLMAEKFEIPALVADVLQVVREWYKYSDSYPGLRRVQYIYANTEESSPMRHMLVHAVARMMVVANTGIPPHWDKALRKNGQLAVDIIRAIQDWRLDEETVPDAREEPAEGEELVDVEGETSKLDEQAEKEIDPKIAGRDDPPASSSSVSADESAEDSEDTVVESPVEETKGVQGAVKGKKEDVKAKTAPVLEKEFGKFSLNERGNADYGTLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCT9</accession>
    <name>W6ZCT9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alcohol dehydrogenase-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_89086</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
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        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZCT9"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="FDH_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
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        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
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        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF1">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="59"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="439" mass="48679" checksum="1017CBD3C1322C6B" modified="2014-04-16" version="1">MQAEKAVGHSDNAITTQDVTNPGNNEAWGDNSEKMKALAWFGKNDVRIVETPKPKVIEPRDVIIKVTGSTVCGSDLHLLHGSVVEMQKGDILGHEFCGVVDECGSEVTKFKKGQRVVASFQIACGDCYYCKQKLSSQCEKTNSNTIENTMYGGRTAGMFGYSHFTGGFAGGQAEYTRVPYGDVNLLPLPDDVPDEQGLYLSDVLCTSWHAVVDTGVKKGDVVAIWGAGPIGQMAADFSLLNGASRVIMIDSNWRLDFIKNKYPHIDTLDFSALPKGESVTSKLKEMCNNRGPDVSIECAAGEYAKGWAHYFEMMLGLETDTSEIVNEMISSTRNMGRCGITGVYVGYTNHFNIGSLMERGIRLIGNGQAPVHMYWESLLQMIQEKRIDPSKMVTHRVRLEDLDKVYYKFEKKEDGMQKVFVETKWSFPASKSSPELTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD43</accession>
    <name>W6ZD43_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">Pkr1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_1540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685528.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19119889"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1540"/>
    <dbReference type="eggNOG" id="ENOG502S6V3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068499_0_0_1"/>
    <dbReference type="OrthoDB" id="9626941at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013945">
        <property type="entry name" value="Pkr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251:SF1">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08636">
        <property type="entry name" value="Pkr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="22100" checksum="159DDE5DD53531C3" modified="2014-04-16" version="1">MASFFEQLWESIFTPGPTPTLLVATNASFAALQLLLFAMLLATYSIHFIILSLLCGGLWWSINWFAAEIRAAQEKEEEAKRIREARRGAKDKGDDGDGEAMDSGDDTEVETEVEQRQVPQPKPKQLRAEAQSTVLVDKPQGNAISSPSPPPVTAGARTTTAATTGLAVPADETTKRRKGMAESTGDLSTDSEWDKLSEDSEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDB4</accession>
    <name>W6ZDB4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PRP1 splicing factor N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_83449</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007685484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDB4"/>
    <dbReference type="STRING" id="930090.W6ZDB4"/>
    <dbReference type="GeneID" id="19126260"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83449"/>
    <dbReference type="eggNOG" id="KOG0495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007010_0_0_1"/>
    <dbReference type="OrthoDB" id="440128at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000256">
        <property type="entry name" value="Probable pre-mRNA splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059164">
        <property type="entry name" value="HAT_PRP39_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010491">
        <property type="entry name" value="PRP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23241">
        <property type="entry name" value="HAT_PRP39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06424">
        <property type="entry name" value="PRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PRP1 splicing factor N-terminal" evidence="8">
        <location>
            <begin position="11"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC49802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="930" mass="103779" checksum="411E30E7851A32E9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEM8</accession>
    <name>W6ZEM8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_2761</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the histone H4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685104.1">
        <property type="nucleotide sequence ID" value="XM_007686914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEM8"/>
    <dbReference type="STRING" id="930090.W6ZEM8"/>
    <dbReference type="GeneID" id="19121149"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2761"/>
    <dbReference type="eggNOG" id="KOG3467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109117_2_3_1"/>
    <dbReference type="OrthoDB" id="3687090at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000007">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0488">Methylation</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="12">
        <location>
            <begin position="44"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC48318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="119" mass="13115" checksum="52DD579F2B6B7752" modified="2014-04-16" version="1">MTGRKYIDIPFVVATLIALGGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISAMIYEETRGVLKTFLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEU0</accession>
    <name>W6ZEU0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase small domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_87457</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685044.1">
        <property type="nucleotide sequence ID" value="XM_007686854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEU0"/>
    <dbReference type="STRING" id="930090.W6ZEU0"/>
    <dbReference type="GeneID" id="19127064"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87457"/>
    <dbReference type="eggNOG" id="KOG3191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018398_6_1_1"/>
    <dbReference type="OrthoDB" id="406152at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035657">
        <property type="term" value="C:eRF1 methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000274">
        <property type="entry name" value="ERF1 methyltransferase catalytic subunit MTQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052190">
        <property type="entry name" value="Euk-Arch_PrmC-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875:SF1">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="27772" checksum="966D5FC92FEDBBB6" modified="2014-04-16" version="1">MLPTPSTSHVCFDRVYEPAEDSYLLLDTISSASETTYLKDRFGDASSTPPLVLEVGVGSGVVLAFVAANAQTIFGRHDALTLGVDINSFACNAAAHTVQNAIQEREKERSIFMDIVNGDLANAIRPGTVDVFIFNPPYVPAELPDLSSHEKYNVIPEGKKATSFEQDSYLLELSYAGGEDGMVVTNRMLEQIPDILSADRGVAYLLLCAQNKPEVVKQRIREWGAGWMAETVGSSGKKAGWEKLVIVRIWREAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEV6</accession>
    <name>W6ZEV6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_82391</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Han J."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        </source>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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    </comment>
    <comment type="cofactor">
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            <name>Mn(2+)</name>
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        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000003">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF34">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="15">
        <location>
            <begin position="53"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00072026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC46089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="384" mass="41564" checksum="C4CC2DD738EBCA01" modified="2014-04-16" version="1">MLAARSFASPARQCLRQANRSRWAPALSQVSARTYASEVAKFHGTKGSDGKYSVTLIEGDGIGPEIAQSVKDIYSAANVPIKWESVDVTPRLNEEGKTVIPDESIASVKKNLVALKGPLATPIGKGHVSLNLTLRRTFNLFANVRPCRSIAGYKTPYDDVDTVLIRENTEGEYSGIEHIVVDGVVQSIKLITREASERVLRYAFQHARDIGRKKVRAVHKATIMKMSDGLFLSTAREIAKDFPDIEFDAELLDNTCLKMVTDPVPYNDKVLVMPNLYGDILSDMCAGLIGGLGLTPSGNIGDNCSIFEAVHGSAPDIAGKQLANPTALLLSSIMMLRHMGLNSEAANIEQAIFKVLAEGKTITGDLGGKAKTYEYADAVIKALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF02</accession>
    <name>W6ZF02_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_36293</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI963972">
        <property type="protein sequence ID" value="EUC46094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687410.1">
        <property type="nucleotide sequence ID" value="XM_007689220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF02"/>
    <dbReference type="STRING" id="930090.W6ZF02"/>
    <dbReference type="GeneID" id="19122989"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36293"/>
    <dbReference type="eggNOG" id="KOG0834">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038278_1_0_1"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000073">
        <property type="entry name" value="C-type cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="55"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="301"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="376"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="385"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="405" mass="45277" checksum="1AC7213A9BA29A05" modified="2014-04-16" version="1">MAPGASTSDRDRVGPHPSYIEIAKPYILQSRMQKCLSDINMSDAKEDAVRLQGVAWIDQVRRALQLPIRTFNTAVIYYHKFRLLHADNEYNWADAAAAALFTACKIEDTLKKSREILCAHWNLKVAPGETLSSDDPRFDSHSKLIIGLERLMLESAGFDFRNRYPQKVMVKLARALRFDANAEAKTTWNLSIDLYRTFAPLKQSTPTLAIACLELAARLHGKDATKFVDAGPVKYSIWATSRAEVMETLLDLLDLYTHHRAATSVGPNYTLEHFLNIRIGLNQEASAANIPRYSQYASEAASETGVTGNGTKSRNGIGPASPLTPATPVTLSPGTEHAPKSAIGIRGQNGTVRFMLDAARAHDERAEVEKFHKVEEEEYEVEVSNDTRPDDRERDRIRVGRVRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFK1</accession>
    <name>W6ZFK1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein PhiA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_29074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964067">
        <property type="protein sequence ID" value="EUC42261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691205.1">
        <property type="nucleotide sequence ID" value="XM_007693015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFK1"/>
    <dbReference type="GeneID" id="19121433"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29074"/>
    <dbReference type="eggNOG" id="ENOG502SNZ2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097238_0_0_1"/>
    <dbReference type="OrthoDB" id="4093325at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887443" description="Cell wall protein PhiA" evidence="1">
        <location>
            <begin position="26"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="22161" checksum="B35D351E59926054" modified="2014-04-16" version="1">MKFTATFAAASLAAISSALPQPTTAYPRPEAGDIFRLMSLRTGTPIHYGNVQAKEGNLVINSPDQFNKTCGINGSRDNVTNGIDYASFSLHDDGSVYLYTFNPPLQLYVDRSGMGQGNVRYSTGVQPIGKNQERGPFKINKDGDLVFAAGGLTGDVGFQACPGAVGGGWKIWLNGVDKPAGSEGCTPFTMKALKETPYYRCLYSSAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFS2</accession>
    <name>W6ZFS2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_81630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC43A transporter (TC 2.A.1.44) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682938.1">
        <property type="nucleotide sequence ID" value="XM_007684748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFS2"/>
    <dbReference type="GeneID" id="19125909"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81630"/>
    <dbReference type="eggNOG" id="ENOG502QRYG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014401_1_1_1"/>
    <dbReference type="OrthoDB" id="330047at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF2">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="507"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="555"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="561"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="587" mass="64585" checksum="D95D9D00B4D3E53B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG19</accession>
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        <recommendedName>
            <fullName evidence="15">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_92785</name>
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    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZG19"/>
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    <dbReference type="eggNOG" id="KOG1082">
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    <dbReference type="HOGENOM" id="CLU_020840_11_3_1"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050973">
        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
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        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF3">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SET-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00468">
        <property type="entry name" value="PreSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Chromo" evidence="9">
        <location>
            <begin position="12"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-SET" evidence="11">
        <location>
            <begin position="248"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="357"/>
            <end position="488"/>
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    </feature>
    <feature type="domain" description="Post-SET" evidence="12">
        <location>
            <begin position="505"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="80"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC46459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="59581" checksum="73B6722A22A6D7C3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGH6</accession>
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        <recommendedName>
            <fullName evidence="1">geranylgeranyl diphosphate synthase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_4383</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.29" evidence="1"/>
    <dbReference type="EMBL" id="KI963964">
        <property type="protein sequence ID" value="EUC46609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686878.1">
        <property type="nucleotide sequence ID" value="XM_007688688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGH6"/>
    <dbReference type="STRING" id="930090.W6ZGH6"/>
    <dbReference type="GeneID" id="19124219"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4383"/>
    <dbReference type="eggNOG" id="KOG0777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_10_0_1"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046165">
        <property type="term" value="P:alcohol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF72">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G01210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="349"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="721" mass="81486" checksum="72FAF4D625D0345A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGT7</accession>
    <name>W6ZGT7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 16">Elongator complex protein 3</fullName>
            <ecNumber evidence="16">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">COCMIDRAFT_23281</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:61020"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
            <dbReference type="EC" id="2.3.1.311"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:61021"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16 17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="16 17">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the ELP3 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="16"/>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684404.1">
        <property type="nucleotide sequence ID" value="XM_007686214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGT7"/>
    <dbReference type="STRING" id="930090.W6ZGT7"/>
    <dbReference type="GeneID" id="19120404"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23281"/>
    <dbReference type="eggNOG" id="KOG2535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025983_2_1_1"/>
    <dbReference type="OrthoDB" id="10265243at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106261">
        <property type="term" value="F:tRNA uridine(34) acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140018">
        <property type="term" value="P:regulation of cytoplasmic translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000003">
        <property type="entry name" value="Elongator complex protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056591">
        <property type="entry name" value="ELP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01211">
        <property type="entry name" value="ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23613">
        <property type="entry name" value="ELP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005669">
        <property type="entry name" value="Hist_AcTrfase_ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01086">
        <property type="entry name" value="elongater_protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00344">
        <property type="entry name" value="ELP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="14 16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11 17" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 16" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 16" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Radical SAM core" evidence="19">
        <location>
            <begin position="102"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="18">
        <location>
            <begin position="416"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR005669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR005669-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EUC49113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="576" mass="65358" checksum="FAEBF9E0F03D096C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH74</accession>
    <name>W6ZH74_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MOSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_79928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682173.1">
        <property type="nucleotide sequence ID" value="XM_007683983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZH74"/>
    <dbReference type="STRING" id="930090.W6ZH74"/>
    <dbReference type="GeneID" id="19125567"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79928"/>
    <dbReference type="eggNOG" id="KOG2362">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028286_3_0_1"/>
    <dbReference type="OrthoDB" id="17255at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF34">
        <property type="entry name" value="MOSC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G07820)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="MOSC" evidence="2">
        <location>
            <begin position="188"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="381" mass="41696" checksum="C47ECA5B2396BD2B" modified="2014-04-16" version="1">MSQPAWLLAALYITPVILVCYYLFGRSSPSSATVKALPEMEISEIYVYPIKSLRAIKLASAIATPHGFAHDRSFMLLEKTPTGYKNMAVASYPQMTQFLQEISPPPDNTSSSSTANSTLTIHYLAHGSTANQSSLTIPLTPSTSTLPTLEISLHDSPTTAYRMPPSYNTWFSTCFGFDVELVYLGSHRRSPRFSNLAPSSPANPAEPKLSHSLTFTDCAPYLITSTPSLSSVSSRIASEMDITKFRPNILLSGAKEAWDEDFWSRICIKSAKEAAAAAGGGEETEIALLHNCVRCKSINIDYATGKPGEGVKGEVLKRLQGDRRVDKGARWSPVFGRYGFWVGGSGGKEKGKEEVVWRVGDKVRVTGVNRERTVWSWPNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHA9</accession>
    <name>W6ZHA9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_84920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684246.1">
        <property type="nucleotide sequence ID" value="XM_007686056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHA9"/>
    <dbReference type="STRING" id="930090.W6ZHA9"/>
    <dbReference type="GeneID" id="19126565"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84920"/>
    <dbReference type="HOGENOM" id="CLU_2967183_0_0_1"/>
    <dbReference type="OrthoDB" id="3690391at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="67" mass="7817" checksum="1769DB1DC1BDC5B2" modified="2014-04-16" version="1" fragment="single">LVQMRTEEIGLNDFLFNRRMLEVVSARCECGERRQTAAHIPLRSRIHKDLRNQVFENLSGRHNLGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHB0</accession>
    <name>W6ZHB0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">MICOS complex subunit MIC12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Altered inheritance of mitochondria protein 5, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Found in mitochondrial proteome protein 51</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_91783</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MICOS complex subunit Mic12 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686641.1">
        <property type="nucleotide sequence ID" value="XM_007688451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHB0"/>
    <dbReference type="GeneID" id="19127950"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91783"/>
    <dbReference type="eggNOG" id="ENOG502SC1K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134520_2_0_1"/>
    <dbReference type="OrthoDB" id="4037694at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044284">
        <property type="term" value="C:mitochondrial crista junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031463">
        <property type="entry name" value="Mic12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17050">
        <property type="entry name" value="AIM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC46804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="112" mass="12749" checksum="48600F3D8D91DFF0" modified="2014-04-16" version="1">MGFTTGFLGGVTLTSAVLYLTISLHAQNRATQAALLRQQRRVLAEFYEPKKPEPDPTSREAPVGLAEMAKDRWNRSLEEGVKKVYSTDWRRVREDVEDRASVILQKIRDSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHJ4</accession>
    <name>W6ZHJ4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="3 10">4.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_22843</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>orotidine 5'-phosphate + H(+) = UMP + CO2</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the OMP decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="3 10"/>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683958.1">
        <property type="nucleotide sequence ID" value="XM_007685768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHJ4"/>
    <dbReference type="STRING" id="930090.W6ZHJ4"/>
    <dbReference type="GeneID" id="19120334"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22843"/>
    <dbReference type="eggNOG" id="KOG1377">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030821_1_1_1"/>
    <dbReference type="OrthoDB" id="10263753at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04725">
        <property type="entry name" value="OMP_decarboxylase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000606">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119:SF2">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="12">
        <location>
            <begin position="37"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="8">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="8">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="8">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC49465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="384" mass="42672" checksum="842ABC273E359ED4" modified="2014-04-16" version="1">MSPHSTLTSTYRARASLSSAGPLASYLLSLIAAKQTNLCLSADVETSAELLQLAEEVGDSICLLKTHCDIVTDWSDRTAQALREIAARKTFLIFEDRKFADIGETVQKQYTSGHHRIALWAEITNAHVLPGPAIVTALEKAAETTIAKYNTSVNTEISATRQVNEAGDDDEDDDEFDQDMKNPDFTIESPIEMEGEERRLSIRAPDRKQSVVSVTTSISMRTESISPRPEPNDNGEDVFNLDTATELIRLGPPPFLRSLLLLAEMSSEGHLMTPEYQKTTVQIARSHRDFVMGFIAQRSLNSEPDDNFITMTPGCQLPPPGQEGKKLGDALGQQYNTPHKLIYDQGCDIIIVGRGIVRAQDRKSEAERYRKAAWSAYEERVRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIL2</accession>
    <name>W6ZIL2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964030">
        <property type="protein sequence ID" value="EUC43416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690075.1">
        <property type="nucleotide sequence ID" value="XM_007691885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIL2"/>
    <dbReference type="GeneID" id="19121252"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28139"/>
    <dbReference type="eggNOG" id="ENOG502RHSB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_676433_0_0_1"/>
    <dbReference type="OrthoDB" id="3909054at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="414" mass="45119" checksum="9106D27A9DAA0500" modified="2014-04-16" version="1">MESRQSSPVARSASPRYSMQRQRSNSFPIIDALGCTTPEAQLILAESRAAVRKRRARRNQSLDEEGGRPFDPRDHIKFLQELAAIPTPQEQPTPFGSSRHAPSHSRIPSDATDRSTSTVVPRDDGSGPVRNISPTLGDYSATLAQFIKNQLKSIPTYQPGSDSSLPLSPRSCPDLSFATQSSRSSSCPSVRRPVEKPRIIEIPPIRAPVKSQFSAWSSTDEDTDDESHALTEYALSLEDSLSKTSSHTPSVLGYYQTSDSGNASSFLFSSTPLEDQSEADAAKAFKFPYQSAQPSSSSGQPDYDHYPSSCSPHPQLTSLSATSAPSFTSSSVSLSYFDCKRPSAITPQMKERVIAAVTPPHLRSKRLSAMSPWDGSALGTSHDVYVESQQRVTVDGMSFDMLRDFNASTRLTPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIM1</accession>
    <name>W6ZIM1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_83730</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683697.1">
        <property type="nucleotide sequence ID" value="XM_007685507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIM1"/>
    <dbReference type="GeneID" id="19126314"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83730"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17327">
        <property type="entry name" value="MFS_FEN2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF1">
        <property type="entry name" value="ALLANTOATE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="58710" checksum="A641E6C20ABC5FE4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIU2</accession>
    <name>W6ZIU2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_100668</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p55 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964027">
        <property type="protein sequence ID" value="EUC43516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691804.1"/>
    </dbReference>
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    <dbReference type="eggNOG" id="KOG1498">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="268763at2759"/>
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    </dbReference>
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        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
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        <property type="entry name" value="RPN5_C"/>
    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="RPN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="267"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="210"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC43516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="495" mass="56897" checksum="DD396BE04A04B495" modified="2014-04-16" version="1">MSAGEVLKADKDFTKEVDAAIPEAEKLASSNPQAGIDKLLALEKQTRQASDLASTSRVIIAIVTIAKNAKDWNLMNEQVLLLSKKHGQLKQATTKMVQTVMGFLDETPNLETKLSVIETLRTVTEGKIFVEVERARVTRILSNIKKEQGDIDSATNILCELQVETFGSMTRREKTEFILQQVALCIQKGDWTQAGILSRKISTRYFARKPKKTPEQLEKEQKEREEKEKNRSVDDPPIEPEDDVTDLKLKYYEQQILLAKHDDKYLDVCKHYRQVLDTEAVEEDPAKLRAILQRVIYFIILAPYDNEQSDLIHRIQRDSRNSQIPQDAQLVKLFTVPELMRWPMVAKQFGPHLTETDVFDAEKGDSDDPKAFQRWQDLRKRVIEHNVRVVAKYYTRIQIPRLTELLDLTEDETEKNISELVSAKTIYAKIDRPARIVTFSRPRDADDVLNEWSSNMKSLLGLLERVDHLITKEEMMARIQPTKVDKSKAIKGKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJS3</accession>
    <name>W6ZJS3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_6776</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964018">
        <property type="protein sequence ID" value="EUC43836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689631.1">
        <property type="nucleotide sequence ID" value="XM_007691441.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZJS3"/>
    <dbReference type="GeneID" id="19125080"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6776"/>
    <dbReference type="eggNOG" id="KOG0383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_18_4_1"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17919">
        <property type="entry name" value="DEXHc_Snf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056616">
        <property type="entry name" value="Chromo_MIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055565">
        <property type="entry name" value="DUF7141"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040934">
        <property type="entry name" value="Znf-CCCH_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041684">
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        <location>
            <begin position="745"/>
            <end position="916"/>
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        <location>
            <begin position="1050"/>
            <end position="1201"/>
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            <begin position="1"/>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="11">
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            <end position="1507"/>
        </location>
    </feature>
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            <begin position="1615"/>
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        </location>
    </feature>
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        <location>
            <begin position="1651"/>
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        </location>
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        <location>
            <begin position="903"/>
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            <begin position="192"/>
            <end position="212"/>
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        <location>
            <begin position="1355"/>
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        </location>
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            <begin position="1369"/>
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        <location>
            <begin position="1651"/>
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            <begin position="1685"/>
            <end position="1700"/>
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        <source>
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        <source>
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        <source>
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        <source>
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        <source>
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        </source>
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        <source>
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        </source>
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        <source>
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        </source>
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    <sequence length="1717" mass="192750" checksum="A6B99F3618C6853B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJT2</accession>
    <name>W6ZJT2_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
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        <name evidence="6" type="ORF">COCMIDRAFT_99739</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
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    </dbReference>
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        </location>
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            <position position="1"/>
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    </feature>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="196" mass="23392" checksum="52D43D73E07EF595" modified="2014-04-16" version="1" fragment="single">VEELQKKKQSDMMRFLMRVRLRQLKVIHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPAPKYTNKPTGKPTNQGINQLKYQRSLKSTAEERVGRRCANLRVLNSYWINQDSTYKYYEVICVDPQHKAIRRDPRINWIVKPVHKHRESRGLTATGKKSRGLGRGHKFNHTTAGRRKTWKRNNTLSLWRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJZ2</accession>
    <name>W6ZJZ2_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_81951</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJZ2"/>
    <dbReference type="ESTHER" id="cocmi-w6zjz2">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="19125963"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81951"/>
    <dbReference type="eggNOG" id="KOG4389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_7_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
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            <begin position="18"/>
            <end position="523"/>
        </location>
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        <location>
            <begin position="21"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="523" mass="57158" checksum="7AB77073BC50299A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKP1</accession>
    <name>W6ZKP1_COCMI</name>
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        <recommendedName>
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        </recommendedName>
    </protein>
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            <taxon>Pleosporaceae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">ATCC 44560</strain>
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        <subcellularLocation>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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        </location>
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        </location>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50563.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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            <fullName evidence="2">BTB domain-containing protein</fullName>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="930090.W6ZLH0"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_87589"/>
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    </dbReference>
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        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
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    </dbReference>
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        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="119"/>
        </location>
    </feature>
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        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="260" mass="28969" checksum="3B532C6FAA679E24" modified="2014-04-16" version="1">MDSVEKLPLGFRVEPKTPHCRGSPVSRTETFPRTPSKPKTKQSILALGDETADFAIICERTRYTAHKAILSASSPYFARMFRFSGSEINNNEVNVPDVDALSMKQVLDYMYTGMYALPYGIPIPATDYCKHSSLALLEGPVSSPKIFKRKCPCAGKCLAPAHLLMHVRIYTAADYLDMFDLKSYAQQGVEDVLHVYWQDDSLELADALEEVFTATPDDDRGMRNVFVDALKEHPGLAVDVGDVRAWLDANPDVDESVNWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
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    <name>W6ZLI2_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_31826</name>
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    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682550.1">
        <property type="nucleotide sequence ID" value="XM_007684360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLI2"/>
    <dbReference type="STRING" id="930090.W6ZLI2"/>
    <dbReference type="GeneID" id="19121971"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31826"/>
    <dbReference type="eggNOG" id="ENOG502SGIR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_475046_0_0_1"/>
    <dbReference type="OrthoDB" id="3355480at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC50935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="64021" checksum="DEC83A72B8AFE571" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM59</accession>
    <name>W6ZM59_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_33915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684837.1">
        <property type="nucleotide sequence ID" value="XM_007686647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM59"/>
    <dbReference type="GeneID" id="19122439"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33915"/>
    <dbReference type="eggNOG" id="ENOG502S2ZP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051199_2_0_1"/>
    <dbReference type="OrthoDB" id="18530at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368:SF1">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889942" evidence="2">
        <location>
            <begin position="27"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="329" mass="35229" checksum="E1C0178C89995192" modified="2014-04-16" version="1">MTPKLSRRPWLPAVALFSFFSTLATALSGQEPLGTLEEQRGYNPGEPIPVSCLNRTIETGEHITDAAGHLQYIPFPVCNETGRPLELFFGIEKDVNCTIDFVTDEFFHLLEFYIHNDAPLSCRIPSKPLPPSVLATQYIVSDSATQEGALGSQSSSYTPLVVALAGTLQLSHLHVGNYLNLLVHAAPKQSSPGTIDAATAYSVSSHTRNTKITIGDSLPLVFAVRWYPSTTLPPGWSGYGGHIYTSTLVYCFLSAVASAAVCVVYFRGVELPRRLKRYATDRMNGGARGFGNGGSGYGLPVANARDGAPGMGSGYGLGGYGYRGGKRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN71</accession>
    <name>W6ZN71_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_2214</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684484.1">
        <property type="nucleotide sequence ID" value="XM_007686294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN71"/>
    <dbReference type="GeneID" id="19120194"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2214"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002763_0_0_1"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000023">
        <property type="entry name" value="Sensor histidine kinase/response regulator, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.40:FF:000083">
        <property type="entry name" value="Sensor histidine kinase/response regulator, putative (AFU_orthologue AFUA_4G00660)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="543"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="1059"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="231"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="427"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="981"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="429"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="981"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="1117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC48954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1186" mass="131235" checksum="49EE8FB1CABB655A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNY0</accession>
    <name>W6ZNY0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_33477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684316.1">
        <property type="nucleotide sequence ID" value="XM_007686126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNY0"/>
    <dbReference type="GeneID" id="19122336"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33477"/>
    <dbReference type="eggNOG" id="ENOG502T3KA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_154716_0_0_1"/>
    <dbReference type="OrthoDB" id="3799998at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="137" mass="15090" checksum="FCDB38026F1C4E3C" modified="2014-04-16" version="1">MDTASNYSQCIEKPDMNHANTKVERDSVNLDATSSTYYDSEPSAQPPRYPDGQEPQSTSTAPRSKAIGQRSAGAPAAVLGSDRKEKTIRERWNDFKERNFGAYDVSEDRAGAASAAEWDMQGGRVVGGLAKPYWRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQI7</accession>
    <name>W6ZQI7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_94177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687540.1">
        <property type="nucleotide sequence ID" value="XM_007689350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQI7"/>
    <dbReference type="GeneID" id="19128403"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94177"/>
    <dbReference type="HOGENOM" id="CLU_3037853_0_0_1"/>
    <dbReference type="OrthoDB" id="3691348at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="59" mass="6224" checksum="47D33710A1ADFA49" modified="2014-04-16" version="1">MLPGYTCVKPLSGNTLTFVVAVTVIVATAPRYGWQSPGTGPVRPFICCSRAIQATLLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSX0</accession>
    <name>W6ZSX0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_4193</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686683.1">
        <property type="nucleotide sequence ID" value="XM_007688493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSX0"/>
    <dbReference type="GeneID" id="19124157"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4193"/>
    <dbReference type="eggNOG" id="ENOG502S43V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054062_0_0_1"/>
    <dbReference type="OrthoDB" id="19714at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039924">
        <property type="entry name" value="ICln/Lot5/Saf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399">
        <property type="entry name" value="CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399:SF0">
        <property type="entry name" value="METHYLOSOME SUBUNIT PICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03517">
        <property type="entry name" value="Voldacs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="254" mass="27609" checksum="41644A1C05DFD50B" modified="2014-04-16" version="1">MSLQHLDSPPKADDFTPLSEHQQQTPASFFGAKPVLHAHYEAMTLSVAADQLQQDPAFSKFSSRREGEEDLVDGVDVWVSSENLILFQNTLSPIGVSIPYPSLALHATMKYKSTIEALYMNISLNDAETVNEDDDIRMLEITVLPPSYATKPTDTCIPEFFAALNTCADLHPDPDASDDEGDNVLDDTAPGASGWITADNMDEYLDEDGNFKGMVIGEELGPGAGTVRTREEADDGSNGVNGADGHEEKYHRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTH4</accession>
    <name>W6ZTH4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Carboxypeptidase M14B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Carboxypeptidase MCPB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_91274</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Extracellular metalloprotease that contributes to pathogenicity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the peptidase M14 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC47026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686524.1">
        <property type="nucleotide sequence ID" value="XM_007688334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTH4"/>
    <dbReference type="STRING" id="930090.W6ZTH4"/>
    <dbReference type="GeneID" id="19127849"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91274"/>
    <dbReference type="eggNOG" id="ENOG502SIAH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026103_1_0_1"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06242">
        <property type="entry name" value="M14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
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        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
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        <property type="entry name" value="INACTIVE METALLOCARBOXYPEPTIDASE ECM14"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Peptidase_M14"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 14" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
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        <location>
            <begin position="17"/>
            <end position="529"/>
        </location>
    </feature>
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        <location>
            <begin position="67"/>
            <end position="342"/>
        </location>
    </feature>
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        <location>
            <position position="313"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003091"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00041263"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00042017"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC47026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="529" mass="57881" checksum="595ED23C43D6DEAB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTQ3</accession>
    <name>W6ZTQ3_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_90828</name>
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    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
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            <taxon>Eukaryota</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="555" mass="62533" checksum="23A4C4CDBC247053" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUB8</accession>
    <name>W6ZUB8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_31705</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="165" mass="18237" checksum="AD619F90CF30ACB6" modified="2014-04-16" version="1">MSFKAKDLHFDSSQPAFLQRLRGQLQSGDTARHEHPIARNKRMNKDDDEDDAPTYVLEDTNQSLSKEEYDALVSGKDGKGEEGPVVADEAEQKATKQDESKPKDKIAEVGANTKKRKAAKIIGDDQGDSKSQVERDAEKPTIKPAKKPKKKAKAVKLTFGDEDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUR9</accession>
    <name>W6ZUR9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_123</name>
    </gene>
    <organism evidence="7 8">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC51324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007683872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUR9"/>
    <dbReference type="STRING" id="930090.W6ZUR9"/>
    <dbReference type="GeneID" id="19119818"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_123"/>
    <dbReference type="eggNOG" id="KOG2668">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030844_1_1_1"/>
    <dbReference type="OrthoDB" id="6080404at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03399">
        <property type="entry name" value="SPFH_flotillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806:SF31">
        <property type="entry name" value="FLOTILLIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="FLOTILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVN7</accession>
    <name>W6ZVN7_COCMI</name>
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            <fullName evidence="12">SET domain-containing protein</fullName>
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            <taxon>Eukaryota</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <text>L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EUC47841.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1344" mass="151300" checksum="C264F1D9EEC2BB2C" modified="2014-04-16" version="1"> </sequence>
</entry>
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        </submittedName>
    </protein>
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            <taxon>Dothideomycetes</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
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    </feature>
    <feature type="coiled-coil region" evidence="1">
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            <begin position="338"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
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            <end position="472"/>
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    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWK1</accession>
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        </recommendedName>
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    </gene>
    <organism evidence="2 3">
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685361.1">
        <property type="nucleotide sequence ID" value="XM_007687171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWK1"/>
    <dbReference type="GeneID" id="19127210"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88151"/>
    <dbReference type="eggNOG" id="ENOG502SE0Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099842_0_0_1"/>
    <dbReference type="OrthoDB" id="2445945at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="177" mass="19660" checksum="8B9A16D5F04955E8" modified="2014-04-16" version="1">MDSNNQPIKPPKPQWRSLTPSNLPTLSHIAATIHPDLAERDAVFLERITLFPKGCLGLFDDSNTLWGYLVSHPIRYQEPPELDSLLGEITQDVDQYYIHDLAILPEARGSRLAQEGVEKVLGTAAQAYKTSGLVSVYGTTSFWRKFGFEKPDVVSVKLGEKLVGYGDGAVYLERKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZWV8</accession>
    <name>W6ZWV8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_87632</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685167.1">
        <property type="nucleotide sequence ID" value="XM_007686977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZWV8"/>
    <dbReference type="GeneID" id="19127104"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87632"/>
    <dbReference type="eggNOG" id="ENOG502RFWB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_0_1"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="37"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="282"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="346"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="367"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC48301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="380" mass="41909" checksum="A9C38EBC89BF640E" modified="2014-04-16" version="1">MAAFESWVSNPDESNGPLMSVVTWSLVSVAAVFLIPRLCIRQRQGKLWLDDCTLAVSWILLLIQVSINQVSINLGYGGHTLDLDLRNLDKLMYIGGAELTIYTIAIALSKISFGLTLLRLTDGWVRLYVYFAISTLAIFAVPATIIPWVQCKPLAKTFVDFIPGECINKHPSVVYGRFQAVWSALMDVSLAMLPWKILSSLQMRTAEKIGVCVAMSLGVLAGVTSIIRSTYIEKLTVQDVSYESYKSIIWAVAECSMAIVATSIPVLRVVFKRAFNSAIEGYTGSSRSKSRSKSRSYPSNAASSGNRMSTRQSSKKMPDIMVSRECGESVEEVFGRGSNRSKNYVELDDLAVDEESGRVTASSPESLPDHAERHIPNWPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX70</accession>
    <name>W6ZX70_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MICOS complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_87353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685075.1">
        <property type="nucleotide sequence ID" value="XM_007686885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX70"/>
    <dbReference type="STRING" id="930090.W6ZX70"/>
    <dbReference type="GeneID" id="19127041"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87353"/>
    <dbReference type="eggNOG" id="ENOG502S70K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072876_0_0_1"/>
    <dbReference type="OrthoDB" id="2399148at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044284">
        <property type="term" value="C:mitochondrial crista junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019166">
        <property type="entry name" value="MIC26/MIC27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033181">
        <property type="entry name" value="Mic26_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28268">
        <property type="entry name" value="MICOS SUBUNIT MIC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28268:SF1">
        <property type="entry name" value="MICOS SUBUNIT MIC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09769">
        <property type="entry name" value="ApoO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC48446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="247" mass="27043" checksum="81FC36A861596EF1" modified="2014-04-16" version="1">MAFRPLLRQRAVVPAMAALSATTIFAPRSVYAEERQEDYSNRKPIYDDIPIDATAPTAPSLPAPSRSAPSEEPVYRPTPTDRLAVQIGRARMALYEQAVRGEKAVDNALTETLRLEHSFTSTIRSLAPPKESGEKVLPGALYVLVASMAGSIVTRNRNILLRASVPLAVGITAANVVLPITSKNVGDLIWTYEERYPVVADTHLRMKKRILQFVETGKAHAQGTVGAVEGKLADTRESLEDWVKKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZYM5</accession>
    <name>W6ZYM5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sec20 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_86451</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SEC20 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684776.1">
        <property type="nucleotide sequence ID" value="XM_007686586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZYM5"/>
    <dbReference type="STRING" id="930090.W6ZYM5"/>
    <dbReference type="GeneID" id="19126858"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86451"/>
    <dbReference type="eggNOG" id="ENOG502S7WD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038503_1_0_1"/>
    <dbReference type="OrthoDB" id="46868at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005606">
        <property type="entry name" value="Sec20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056173">
        <property type="entry name" value="Sec20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12825">
        <property type="entry name" value="BNIP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12825:SF0">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SEC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03908">
        <property type="entry name" value="Sec20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Sec20 C-terminal" evidence="13">
        <location>
            <begin position="174"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="312"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="56"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="411"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC48776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="444" mass="49624" checksum="C0A5DED0086C3BFA" modified="2014-04-16" version="1">MAPIPSTTQSLTTRLTALAESNKAVGQLIQRLAKLDFQPGSQPLDPTEGEVRLELGAEIHETLKGIEEELELLRQEVEDITQGGIAGRRRDSSKESERSRLAVLLARLTEDLKSSRAQYRKAQLTAKHNADRAKLKERELLFSNLQSGSSTPSSTYRQRRQQQGTSEGDIVAQASSDVTAALRRTHQLMRDELSRSRFAQETLEQSTAALENLGDNYSDLNTLLANSKTLVSTLLKSQKSDTWYLETTFYVLITTVIWLVFRRWLYGPLTWFVFWPLKLAFRILFAVAPIGAASSAVSSSVAASSSSSRTLVVQPSAAGGIPRREPNGQPHYIPVGRGGPKQDQDPSPPGSYSQQVGKMAEQSQQQQQQQEEVPDHPQFRQPRKDEDDGPVTLGDGTVLKESSKPRNPKKKMWDEDVEQKKLQEEQQQHEQQQEASGERNHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W7A186</accession>
    <name>W7A186_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_57272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683683.1">
        <property type="nucleotide sequence ID" value="XM_007685493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A186"/>
    <dbReference type="STRING" id="930090.W7A186"/>
    <dbReference type="GeneID" id="19124717"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_57272"/>
    <dbReference type="eggNOG" id="ENOG502SN0Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002639_8_3_1"/>
    <dbReference type="OrthoDB" id="5362512at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF9">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="4"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="257" mass="30246" checksum="D16379E3FBA23A8B" modified="2014-04-16" version="1" fragment="single">VTDYICLSHCWGSDEMFKTTIENISERMHNIRFNDLPATFRDAVRITRDLGKRHLWIDSLCIIQNDPRDWRDEGLRMHEIYGNSYLTIVASKTKGPDDGLFSVSSRYKLQDFLFMMDRKQFVMHVRQKVTHFNSIDSFPLLKRGWVFQERILSRRMVHFGPQELVWECMEMEECECGNVDEGISWNSRTPRKSLLLMEGNPFLWNRIAAAYSSLSLTKENDVLPALSGIAKKHKPEPEARYLAGFWDGKFMIFHLLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3M0</accession>
    <name>W7A3M0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Stress response RCI peptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682806.1">
        <property type="nucleotide sequence ID" value="XM_007684616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3M0"/>
    <dbReference type="GeneID" id="19125370"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_772"/>
    <dbReference type="eggNOG" id="ENOG502S98A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107649_0_0_1"/>
    <dbReference type="OrthoDB" id="2802411at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF57">
        <property type="entry name" value="PLASMA MEMBRANE PROTEOLIPID 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="17754" checksum="8187F39F899E77D2" modified="2014-04-16" version="1">MCGSDCFLMLLSVLFPPIGVWVKKGICSADSLINLGLSCLGFLPGLLHAWYVILQNPDPYDAYQTVPDREHGRSTDGRVTYYVISHEQAGGRPANYGTVASQPSSGQFPGQQSGVTNSFAPPQGHKSANGSGPAAPAPANGGGEGSSSQPEGPPPTYADVIKGDHKIQDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W7A5D9</accession>
    <name>W7A5D9_COCMI</name>
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        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_79677</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A5D9"/>
    <dbReference type="STRING" id="930090.W7A5D9"/>
    <dbReference type="GeneID" id="19125524"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79677"/>
    <dbReference type="eggNOG" id="KOG0296">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_9_1"/>
    <dbReference type="OrthoDB" id="10261640at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="131"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="329"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC51346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="512" mass="53125" checksum="BC840994F1584EA4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJA7</accession>
    <name>W6YJA7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_111557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964453">
        <property type="protein sequence ID" value="EUC39452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007694029.1">
        <property type="nucleotide sequence ID" value="XM_007695839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YJA7"/>
    <dbReference type="STRING" id="930090.W6YJA7"/>
    <dbReference type="GeneID" id="19119792"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111557"/>
    <dbReference type="HOGENOM" id="CLU_3147158_0_0_1"/>
    <dbReference type="OrthoDB" id="3689183at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="49" mass="6041" checksum="2E6D8D135B212CCA" modified="2014-04-16" version="1" fragment="single">FNFKITYYVRILNRVVEALSRRFNLRKKGYKELYNVLLKIILNSSLRYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJT1</accession>
    <name>W6YJT1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Homing endonuclease LAGLIDADG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_111007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964298">
        <property type="protein sequence ID" value="EUC39632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693849.1">
        <property type="nucleotide sequence ID" value="XM_007695659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YJT1"/>
    <dbReference type="STRING" id="930090.W6YJT1"/>
    <dbReference type="GeneID" id="19119701"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111007"/>
    <dbReference type="eggNOG" id="ENOG502SFWP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057749_0_0_1"/>
    <dbReference type="OrthoDB" id="3665149at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051289">
        <property type="entry name" value="LAGLIDADG_Endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181">
        <property type="entry name" value="INTRON-ENCODED ENDONUCLEASE AI3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181:SF4">
        <property type="entry name" value="LAGLIDADG ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00961">
        <property type="entry name" value="LAGLIDADG_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="31"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Homing endonuclease LAGLIDADG" evidence="1">
        <location>
            <begin position="190"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="321" mass="36860" checksum="9BD52761434EE031" modified="2014-04-16" version="1">MRIKNKTWLAKFNLNPAFSANLNKLHPAYVTGFCDGEACFHLAIGENPRYKLGYYVNPGFSIALHKKDEEFLLLLKEFFGGVGVVKPSSRSNMVEYRIFAIKDLDIILNHFDLYPLITKKGGDYLLFKEALECIKNKQHLTVEGFNKILAIRASMNKGLPAKLLEKFPYIKGKEIPVVVTPESLNPYWVAGFMDAEGCFFVKSIYNKNNELRFGLGCQITQHSRDSLVMHKICSFFNCGRVEVSRMVYDNYVVTKLPDINKIIIPFFTNFPILGSKRKEFECWTDIAKIMTSKAHLTNEGSEKILKIKHQMNTFRKEDDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLB4</accession>
    <name>W6YLB4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_109961</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964212">
        <property type="protein sequence ID" value="EUC39992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693490.1">
        <property type="nucleotide sequence ID" value="XM_007695300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLB4"/>
    <dbReference type="SMR" id="W6YLB4"/>
    <dbReference type="STRING" id="930090.W6YLB4"/>
    <dbReference type="GeneID" id="19119523"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109961"/>
    <dbReference type="eggNOG" id="KOG2684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_5_3_1"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099115">
        <property type="term" value="C:chromosome, subtelomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031934">
        <property type="term" value="C:mating-type region heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005721">
        <property type="term" value="C:pericentric heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033553">
        <property type="term" value="C:rDNA heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032041">
        <property type="term" value="F:histone H3K14 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141222">
        <property type="term" value="F:histone H3K4 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046969">
        <property type="term" value="F:histone H3K9 deacetylase activity, NAD-dependent"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046970">
        <property type="term" value="F:histone H4K16 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031508">
        <property type="term" value="P:pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902794">
        <property type="term" value="P:siRNA-independent facultative heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF9">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="151"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="318"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC39992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="493" mass="55223" checksum="1E64A24C1D03A5DB" modified="2014-04-16" version="1">MAAHASEGPVAVHDSAPPPAPAGKAEHTAGGATKPKEEDAPAPDHDDEDGGVWDSASLYEEILDEVEAFEYSNDGKDVCTADEARRLRQRLHEVGASQFVMENITSEKMTARKLCTAFGVRIPKFLEEAPDENFYQLLGLAINRELNKRPRLEQYKTIDDAAKLLLERKNIMIITGAGISTSLGIPDFRSKNTGFYSRLLQMGYDEPEEVFDIHNFDENPRTFYALAGDIIPDLEKWTPTHEFIRLLQDKEKLLTNYTQNIDNVEAHAGIRKDKLIQCHGSWATATCRKCKFKVPGEAIFDDVRAQRPAECQRCKDEIAAQPSKKRKRQSNANGSRKKRSSDEDSESDGAFDIPQPGIMKPDITFFGEALPNDFFDRLKDVDKDKVDLVIVMGTSMKVAPVSEIPNFLPRDIPQIYISRDPIHHINFDINLLGDCDVVVAELARRAGWQLNHKMIPEGQTVDVTLTDDMDHISTVKARTPVTITTNNHINEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLQ3</accession>
    <name>W6YLQ3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_41480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964193">
        <property type="protein sequence ID" value="EUC40142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693334.1">
        <property type="nucleotide sequence ID" value="XM_007695144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLQ3"/>
    <dbReference type="STRING" id="930090.W6YLQ3"/>
    <dbReference type="GeneID" id="19124066"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41480"/>
    <dbReference type="HOGENOM" id="CLU_047020_0_0_1"/>
    <dbReference type="OrthoDB" id="5428055at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="540" mass="62081" checksum="9648156BA9880B8D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YN42</accession>
    <name>W6YN42_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_52771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964144">
        <property type="protein sequence ID" value="EUC40707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692762.1">
        <property type="nucleotide sequence ID" value="XM_007694572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YN42"/>
    <dbReference type="STRING" id="930090.W6YN42"/>
    <dbReference type="GeneID" id="19124557"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_52771"/>
    <dbReference type="eggNOG" id="ENOG502RZNG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1664856_0_0_1"/>
    <dbReference type="OrthoDB" id="3910313at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="1">
        <location>
            <begin position="15"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="173" mass="20153" checksum="B6B75D5E275EDF82" modified="2014-04-16" version="1" fragment="single">MMKQKPRAQADRIDDATWNQHRETIHRLFILENRKLEGPEGVMEVMSRVHSFHWSSSSKAQYEARLRSWNLRKKITEREWAVVLLHVHTRARHGKKTLVIFNGALLDEERVTREINRRLSRYHGRPNILQDLPRIPLGFRLESPPSSPVPYADNAISGHNPTDCVDPDLLLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNF2</accession>
    <name>W6YNF2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_30263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964134">
        <property type="protein sequence ID" value="EUC40867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692616.1">
        <property type="nucleotide sequence ID" value="XM_007694426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNF2"/>
    <dbReference type="GeneID" id="19121650"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30263"/>
    <dbReference type="HOGENOM" id="CLU_1854900_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="138" mass="14976" checksum="BCAE63D17446E076" modified="2014-04-16" version="1">MKLCLAAPVVRLLAAPLWIELWRFFISSLSSPRRSSIRQMLDIQTQRAASSVSGQVSQPLCGSRGDASLRESQSCPVRNLAKTPLMNIHSGGTSSAGAHTPQGTPFHHVWQGVDNVCHHQNQCYPSPGTGTHTETWCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQC6</accession>
    <name>W6YQC6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome b/b6 N-terminal region profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_41716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964237">
        <property type="protein sequence ID" value="EUC39850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693630.1">
        <property type="nucleotide sequence ID" value="XM_007695440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQC6"/>
    <dbReference type="GeneID" id="19124119"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41716"/>
    <dbReference type="HOGENOM" id="CLU_2589586_0_0_1"/>
    <dbReference type="OrthoDB" id="3681248at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886097" description="Cytochrome b/b6 N-terminal region profile domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8803" checksum="D672307C4D6B0FF8" modified="2014-04-16" version="1">MVLLMALHIYSILTKGASQSCVFLSRLFTNRFLDCLPKIGFIVSIPFQSGMLILKKKDIQSNIQVHTQQSPTKLMESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQS8</accession>
    <name>W6YQS8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_105217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964086">
        <property type="protein sequence ID" value="EUC41787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691692.1">
        <property type="nucleotide sequence ID" value="XM_007693502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQS8"/>
    <dbReference type="STRING" id="930090.W6YQS8"/>
    <dbReference type="GeneID" id="19118649"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105217"/>
    <dbReference type="eggNOG" id="ENOG502S8JK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077442_2_0_1"/>
    <dbReference type="OrthoDB" id="42525at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009784">
        <property type="entry name" value="DUF1349"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332:SF2">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07081">
        <property type="entry name" value="DUF1349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="212" mass="23806" checksum="C99C87925C976A89" modified="2014-04-16" version="1">MSGSTTIKTIEPFNLSAQAGTDIWRKPPSTNVFNAAFYPSTLPTYPLKQFQRAKITFALPPSNELRRYDQAGLVLHLTKEGVAENATKWVKTGIEFYTGKPFVATVGCDIWADWSLVPMPEFVNGTKPTATIEARKEQDELGKSLWIYWIVRDEQGKEVERRPLREVNWFTAAEDEGWDVSIAGYVARPTTAGGDELLEAEFKDGLEIEVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR82</accession>
    <name>W6YR82_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_109560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964193">
        <property type="protein sequence ID" value="EUC40145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693337.1">
        <property type="nucleotide sequence ID" value="XM_007695147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR82"/>
    <dbReference type="GeneID" id="19119454"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109560"/>
    <dbReference type="HOGENOM" id="CLU_2291192_0_0_1"/>
    <dbReference type="OrthoDB" id="10458353at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="101" mass="10968" checksum="16B7FA2CD59B03BD" modified="2014-04-16" version="1">MLEVAYTTCAIPSPSPRPTALSCKNKSLADHGMDRTRSQESKPRTLLAPLQHGRPPLSPRGRPEAIHRVAVRHEAHRARTPKGKEARRPAAKGKGRPALGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR88</accession>
    <name>W6YR88_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_109872</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964208">
        <property type="protein sequence ID" value="EUC40018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693462.1">
        <property type="nucleotide sequence ID" value="XM_007695272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR88"/>
    <dbReference type="STRING" id="930090.W6YR88"/>
    <dbReference type="GeneID" id="19119509"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109872"/>
    <dbReference type="HOGENOM" id="CLU_144903_0_0_1"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="66" mass="7219" checksum="B37C28D6BA23F631" modified="2014-04-16" version="1" fragment="single">SIVKLTDSSTKVVFRIKEFYSLAEELPTSLRHTSTELPVLSTALESIVQNSELEAALLSLVSGCHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRP0</accession>
    <name>W6YRP0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase small domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964192">
        <property type="protein sequence ID" value="EUC40153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693327.1">
        <property type="nucleotide sequence ID" value="XM_007695137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRP0"/>
    <dbReference type="GeneID" id="19129412"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9916"/>
    <dbReference type="eggNOG" id="ENOG502S5BS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030437_1_0_1"/>
    <dbReference type="OrthoDB" id="433955at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF147">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE OF THE SEVEN BETA-STRAND FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="42623" checksum="284389E295154E34" modified="2014-04-16" version="1">MSGSLTGSCLPPSSSLPPIRLLVSLPEAQITSALKHLRALYCPVRLPTVISTPVSKRDQQSITSPPAPVDSGYASQDEDEDEQETSLEELTAALRADPFERAFTTQWLNTLLARSEEMEMDEEARERIVDHAAFILSSLFESSNTDEDQALTRDFSFSMPSGKAIQVTLNDAPLSSTDHTAVGLQSWGASIVLSSMMCADPKRFALDPSGLAPAPKITELGAGTGLVSLVLAKLLPAINIHDGDIAATDYHPAVLENCKLNIQTNFPSSCTDASLHVSTAILDWAQPPQALKATSNLLIASDVVYAPEHAAWLRDCAAHMLTLDGTFWLMVTVRKTGKFEGIPDTVESAFVPEKCPKNASGMVFCILEKDFVEKKRGIGRGDESGYNLYRIGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSY4</accession>
    <name>W6YSY4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SGT1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_108246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964148">
        <property type="protein sequence ID" value="EUC40648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692820.1">
        <property type="nucleotide sequence ID" value="XM_007694630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSY4"/>
    <dbReference type="STRING" id="930090.W6YSY4"/>
    <dbReference type="GeneID" id="19119210"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108246"/>
    <dbReference type="eggNOG" id="KOG2406">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006241_2_0_1"/>
    <dbReference type="OrthoDB" id="27237at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010770">
        <property type="entry name" value="Ecd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060:SF0">
        <property type="entry name" value="PROTEIN ECDYSONELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060">
        <property type="entry name" value="SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07093">
        <property type="entry name" value="SGT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="608" mass="68833" checksum="5E9B19C6D5629374" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTE9</accession>
    <name>W6YTE9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferritin-like diiron domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_102779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964051">
        <property type="protein sequence ID" value="EUC42727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690763.1">
        <property type="nucleotide sequence ID" value="XM_007692573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTE9"/>
    <dbReference type="GeneID" id="19118155"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102779"/>
    <dbReference type="eggNOG" id="ENOG502RXKA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029630_0_0_1"/>
    <dbReference type="OrthoDB" id="1001765at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052965">
        <property type="entry name" value="Pigment-catalase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31694">
        <property type="entry name" value="DESICCATION-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31694:SF26">
        <property type="entry name" value="OS05G0151100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886214" description="Ferritin-like diiron domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="31622" checksum="F516BF516FF779EE" modified="2014-04-16" version="1">MKSTIFTAAALAALTTASPISRRADGPTDGEILNYALTLEHLEATFYKDALAKYSSADFTSANFTTETYERVKTIAADEAAHVSFLTAGLKAAGATPVEACTYDFGYTDVASFLATASVLEGVGVSAYLGAAADIMSKTYLTAAGSILTVEARHAAYIRNSIGEAPFPAPFDNPLGYNEVYTLAAQFIKSCPDSNPKLPVKAFPVLSAKPKDEGKMGVYGGDDIMVATKGYKIEGTVYAAFITVTGPVFVDAKAVEGGFEVMVPKEGVTGQSYLVLTNCNTAATDDTIVAGPVIVEIMAKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUL7</accession>
    <name>W6YUL7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Histone acetyltransferase type B catalytic subunit</fullName>
            <ecNumber evidence="2 7">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_106714</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the HAT1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2 7"/>
    <dbReference type="EMBL" id="KI964113">
        <property type="protein sequence ID" value="EUC41240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692253.1">
        <property type="nucleotide sequence ID" value="XM_007694063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUL7"/>
    <dbReference type="STRING" id="930090.W6YUL7"/>
    <dbReference type="GeneID" id="19118910"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106714"/>
    <dbReference type="eggNOG" id="KOG2696">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036024_2_1_1"/>
    <dbReference type="OrthoDB" id="10253098at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.360.10">
        <property type="entry name" value="Histone acetyl transferase 1 (HAT1), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019467">
        <property type="entry name" value="Hat1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037113">
        <property type="entry name" value="Hat1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017380">
        <property type="entry name" value="Hist_AcTrfase_B-typ_cat-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12046">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10394">
        <property type="entry name" value="Hat1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038084">
        <property type="entry name" value="HAT-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histone acetyl transferase HAT1 N-terminal" evidence="13">
        <location>
            <begin position="8"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with histone H4 N-terminus" evidence="9">
        <location>
            <begin position="47"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="480"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="426"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="489"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="277"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with histone H4 N-terminus" evidence="10">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR038084-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038084-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038084-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC41240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="513" mass="59153" checksum="9FB1A1A4D44302B5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX10</accession>
    <name>W6YX10_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCD97-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_29243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964074">
        <property type="protein sequence ID" value="EUC42058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691403.1">
        <property type="nucleotide sequence ID" value="XM_007693213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YX10"/>
    <dbReference type="GeneID" id="19121468"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29243"/>
    <dbReference type="eggNOG" id="ENOG502SFGZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076914_0_0_1"/>
    <dbReference type="OrthoDB" id="333176at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040233">
        <property type="entry name" value="CCD97-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018613">
        <property type="entry name" value="Ccdc97-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31840">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31840:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09747">
        <property type="entry name" value="CCD97-like_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCD97-like C-terminal" evidence="2">
        <location>
            <begin position="69"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="CCD97-like C-terminal" evidence="2">
        <location>
            <begin position="164"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="242" mass="27806" checksum="7659B94FE01702AB" modified="2014-04-16" version="1">MAPLALRPANAPEAAKHPADSHNDPEADDIIPTSANEDVAMEDTVDYSLLRDQMRQQQDQRAQRLQAKNRRKRYLEVHPEYFTDSSLELADPLLYDRLIRRFQTASEREAEGRKKGFSGQMATDLWRAEAKKDALSQPDPNSLFTYTRGPQGEIIEEDKDDIPMTKEEGKAWWIDEMTQRFLRGGDDDFDYAKLVDGNPKYDDPEQERDLQDAYFESMESDFDSDGEGKEKVLTGETGIQDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXS7</accession>
    <name>W6YXS7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_9740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964171">
        <property type="protein sequence ID" value="EUC40364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693112.1">
        <property type="nucleotide sequence ID" value="XM_007694922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXS7"/>
    <dbReference type="GeneID" id="19129054"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9740"/>
    <dbReference type="eggNOG" id="ENOG502SXBP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_852600_0_0_1"/>
    <dbReference type="OrthoDB" id="3691767at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="322" mass="36249" checksum="4C23C6C1B5866D95" modified="2014-04-16" version="1">MTIIPKYGDWITFPLEQLSPVELEWWSDKTQQQARYYVDKCWFGDRVDKTDSEDGYRKGLAPKGETLIFIASEYIERRMQGAPHLKNLHLADIMEKKYKDKDAARNWALLQLDEKFHYGQNNGKTFRWIVYHPPAIAGRERKMYQHRFVENVALKIANLGIELAGIAVSTTTGAVTSGKVQVTGIVPILTRVKNLFAANKGHALHQFSSSEQAVSDPPKPGSQDPQSVITTTLSNGTVAKVQEPVNSAYPLISMQEPDEIVFLDIEDETHNTPSQTKVPASQFGKKQMGVGNLRHEEQSELVAPRNIQHSSPGFHIKKEKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY30</accession>
    <name>W6YY30_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_53227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689244.1">
        <property type="nucleotide sequence ID" value="XM_007691054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY30"/>
    <dbReference type="STRING" id="930090.W6YY30"/>
    <dbReference type="GeneID" id="19124576"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_53227"/>
    <dbReference type="eggNOG" id="ENOG502SUZ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_6_2_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="40"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="139" mass="16181" checksum="109DF90BDA113099" modified="2014-04-16" version="1" fragment="single">MDHFQYKPLDPNGNHIRLLRFSDELGYALDSFDLNQCPPYEALSYTWGPPLPTSTITVNEKPFEIRENLSDFLDRIRIGITLLDKHDCPLLHPKYLWIDQLCINQASEEEKSHQVSRMAGIYKQAQRVIVWLGRGDEHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YY51</accession>
    <name>W6YY51_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">homogentisate 1,2-dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_98703</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.5" evidence="4"/>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689255.1">
        <property type="nucleotide sequence ID" value="XM_007691065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YY51"/>
    <dbReference type="STRING" id="930090.W6YY51"/>
    <dbReference type="GeneID" id="19129313"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98703"/>
    <dbReference type="eggNOG" id="KOG1417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027174_0_1_1"/>
    <dbReference type="OrthoDB" id="1689029at2759"/>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07000">
        <property type="entry name" value="cupin_HGO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000034">
        <property type="entry name" value="Homogentisate 1,2-dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046451">
        <property type="entry name" value="HgmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046452">
        <property type="entry name" value="HgmA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056:SF5">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20510">
        <property type="entry name" value="HgmA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase N-terminal" evidence="14">
        <location>
            <begin position="36"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase C-terminal" evidence="13">
        <location>
            <begin position="315"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC44262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="538" mass="60820" checksum="8995685F3E26C30E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYB4</accession>
    <name>W6YYB4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peptidase S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_103191</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI964057">
        <property type="protein sequence ID" value="EUC42563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690935.1">
        <property type="nucleotide sequence ID" value="XM_007692745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYB4"/>
    <dbReference type="GeneID" id="19118244"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103191"/>
    <dbReference type="eggNOG" id="ENOG502QZ4I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013783_4_0_1"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
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                <person name="Han J."/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587:SF2">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886936" evidence="2">
        <location>
            <begin position="18"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="583" mass="65621" checksum="5ABC59CDC60ED9D4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZL8</accession>
    <name>W6YZL8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Vacuolar protein sorting-associated protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_101866</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the VPS29 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964041">
        <property type="protein sequence ID" value="EUC43060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690444.1">
        <property type="nucleotide sequence ID" value="XM_007692254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZL8"/>
    <dbReference type="STRING" id="930090.W6YZL8"/>
    <dbReference type="GeneID" id="19117954"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101866"/>
    <dbReference type="eggNOG" id="KOG3325">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063749_0_1_1"/>
    <dbReference type="OrthoDB" id="10258130at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07394">
        <property type="entry name" value="MPP_Vps29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000024">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028661">
        <property type="entry name" value="Vps29"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN VPS29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="6">
        <location>
            <begin position="7"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC43060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="200" mass="21716" checksum="DFB4B8B6C7022491" modified="2014-04-16" version="1">MASRLVLVLGDLFIPDRASDIPAKFKKLLAPGKIGQILCLGNITDRETYEFLRGIAPDLQIVKGDFDVEAPNLALSKVVTHGSLRIGFTHGHTIIPPGDGDSLLIAARQMDVDVLLWGGTHKFEAYEMEGKFFVNPGSATGAMSTGWWPEDEDPTPSFVLMDVQGDVLVLYVYQLRKDAEGNENVAVEKVSFRKNGGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z084</accession>
    <name>W6Z084_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 8 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_96503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688398.1">
        <property type="nucleotide sequence ID" value="XM_007690208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z084"/>
    <dbReference type="STRING" id="930090.W6Z084"/>
    <dbReference type="GeneID" id="19128864"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96503"/>
    <dbReference type="eggNOG" id="ENOG502SWVM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061610_0_0_1"/>
    <dbReference type="OrthoDB" id="5367275at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="391" mass="43979" checksum="62ABF58651372F38" modified="2014-04-16" version="1">MGRLLLTSGQVSVLLSITIVFFFTLALFLSGWVLQQRYVHSLQAAIKPRLPKPLPPPKPIEPPTLDAKWARPMGSRPEVDDTYAQYISGLTMDWSRLGYVQVVREHVELCSAVMLLSDLHRMKSPAKRILMFPKLWLVESEDNKYSAEMTTTRRLLRTAARRYGVKLIPMSPLVEGADDTLPSSYSLASLYSLVDYERLLYLQGPGVLLDASALDSLLAFSKSEPMAAYPATAERTDMSTSLLMIHPSQQSYNQLRALRASKPTSDLNMFRKTFSVPDSLISEWSLSMGNVVYESQQLRQASDDFNATAFEQATTFVRLSDPELPGPEYDVPYAERARLRPQNEEAQEAWSGLYERFRQRRMEVCGLDLETYEAVAVSGGAAETERTAAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z093</accession>
    <name>W6Z093_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_5675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688373.1">
        <property type="nucleotide sequence ID" value="XM_007690183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z093"/>
    <dbReference type="STRING" id="930090.W6Z093"/>
    <dbReference type="GeneID" id="19124697"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5675"/>
    <dbReference type="eggNOG" id="ENOG502RYR6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022491_3_3_1"/>
    <dbReference type="OrthoDB" id="3056235at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF17">
        <property type="entry name" value="SEXUAL DEVELOPMENT REGULATOR VELC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="234"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="426"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="449" mass="50369" checksum="E78E55F356080601" modified="2014-04-16" version="1">MTETQKPPVFSPPGFLDYSHRRLPPLEIPPDAVPQRPDHHFRSPINQLPSIHSGLPPRNDYHPQPPATHRPAAAPVDKLLQPSNPYTPPRSDPPYSPRQYGPPISPHSEYDSRGPRRLAEQRYSYEEHRPFQRHPPHPEQGGYSSLTSPVEPPHQRSYPPLPSPAYTPSYASSSTPYRGSVGSLQHARSQRGSIGGPLAPIAYSEPSTAAPPPPKQVRPVPLPGSIPQPVYNEQLNLNYELRVRQQPIAARACGFGERDRRVIDPPPIIQLLVTDPKTGAAEQEELRYSLNVVHCTLWNAEGTNEETALVQPDRRTTRRLMGQLVASPSVAKDEHDVEGCFFCFPDLSCRTHGKYRLRFVLMRIDPMNLHVGGFSPILTEVLSDVFTVYTAKDFPGMRPSSALTRALKLQGCNIQVKKGNEKALARKRLTASQEHDNAEEEELKRRRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0H9</accession>
    <name>W6Z0H9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_96079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688265.1">
        <property type="nucleotide sequence ID" value="XM_007690075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0H9"/>
    <dbReference type="GeneID" id="19128780"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96079"/>
    <dbReference type="eggNOG" id="ENOG502SSHC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098343_0_0_1"/>
    <dbReference type="OrthoDB" id="2151982at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="198" mass="21965" checksum="E39A3E8260B68543" modified="2014-04-16" version="1">MNRNTNTDEDTDTDIYKDTNVILNVPVLPPLPRLVATPTAYSGSCLALSPQLIAYLQTLLAPPPCITVSIGSGFGLLEAYIMNGPDTFHIIGVEVAPSPNKYLPSSHHRLVTGTRFLEPLAETARIWLFVYPRRIGLIQEYMATYGQGAVERIIWAGPKADWDDYRACFANWTLQEQEADMVGGRAWELIVVADKKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0V7</accession>
    <name>W6Z0V7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="3">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_27927</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="3"/>
    <dbReference type="EMBL" id="KI964024">
        <property type="protein sequence ID" value="EUC43595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689867.1">
        <property type="nucleotide sequence ID" value="XM_007691677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0V7"/>
    <dbReference type="STRING" id="930090.W6Z0V7"/>
    <dbReference type="GeneID" id="19121207"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27927"/>
    <dbReference type="eggNOG" id="KOG2529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032087_4_2_1"/>
    <dbReference type="OrthoDB" id="9995526at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="7">
        <location>
            <begin position="67"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="231"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="412"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="482" mass="53351" checksum="65D40A9E69ACA1B1" modified="2014-04-16" version="1">MATSPKESRKKVLEGIFAVNKTQWASSAGVLRDLQEHFARSSLLAPWLESQKRSLILSHAKQKHINNLKVKLGHGGTLDPMATGVLIVGLGRGTKCLQRFLECTKTYECVVLFGAATDSYDAVGKIVSKAPYEHVTKELVEEKLAQFRGKIMQKPSVFSALKVDGKKMYEYAREGKEIPEVAARPVEVEELELVEWLEPGSHEYAWPKDEVDGVEMEGAKKLLGIREEDAKIHANTMARKGRKRSRSPESDGVEGAGKQPKMPKSETELAISGALPSQDTPAEAAETTQDETTQAATNSALPTEEKPEPTSEQTEIADQGQPSNEESTTSAQSPPQPPAARLRMTVTSGFYVRSLCHDLGLACSSLGLMSSLIRSRQGAYTLGQNVIELSDFESAEKWEPQLQQQLEEFMEKEGWEAEELEDDETWQEKKKERLSERKDEDRERSYRGGGGGGGGGKNKWNKGKGKYSRNQYSKNMDGGKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0Z5</accession>
    <name>W6Z0Z5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Actin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_38433</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the actin family. ARP1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964023">
        <property type="protein sequence ID" value="EUC43630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689833.1">
        <property type="nucleotide sequence ID" value="XM_007691643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0Z5"/>
    <dbReference type="STRING" id="930090.W6Z0Z5"/>
    <dbReference type="GeneID" id="19123462"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38433"/>
    <dbReference type="eggNOG" id="KOG0676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027965_0_2_1"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10216">
        <property type="entry name" value="ASKHA_NBD_Arp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000015">
        <property type="entry name" value="Actin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000018">
        <property type="entry name" value="Actin-like protein (Centractin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC43630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="42242" checksum="4D0458F310D2D7FF" modified="2014-04-16" version="1">MGSRLHNAPIVIDNGSGTIRAGFAGEDVPKCFFPSYVGRPKHVRTMAGALEGDVFIGPQAQQYRGLFKINYPLEHGIVTDWDDMERIWQYVYTEGLRTVSEDHPVLLTEPPLNPRENRDTAAQILFETFNVPALYTSVQAVLSLYASGKTTGLVLDSGDGVSHAVPVFQGFAIPNSIRRIDVAGRDVTEHLQQLLRKSGRIFHTSAEKETVKNIKEATGYVALDPAKEEKDWSGSSRSEGKSIDYTLPDGQKLRVGAERFRAPEILFNPEIIGLEYPGVHQIVVEAIHRTDMDLRKALYGNIVLSGGSTLTKGFGNRLLHEVQRLAVKDMRIKILAPPERIYTTWTGGSILAGLSTFKKMWVEKDEWQENPDIIHTKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z158</accession>
    <name>W6Z158_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWR1-complex protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_56950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SWC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963983">
        <property type="protein sequence ID" value="EUC45507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688004.1">
        <property type="nucleotide sequence ID" value="XM_007689814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z158"/>
    <dbReference type="STRING" id="930090.W6Z158"/>
    <dbReference type="GeneID" id="19124706"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_56950"/>
    <dbReference type="eggNOG" id="KOG4776">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062474_0_0_1"/>
    <dbReference type="OrthoDB" id="445677at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011421">
        <property type="entry name" value="BCNT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027124">
        <property type="entry name" value="Swc5/CFDP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407:SF1">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07572">
        <property type="entry name" value="BCNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51279">
        <property type="entry name" value="BCNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCNT-C" evidence="4">
        <location>
            <begin position="273"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="146"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC45507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="355" mass="39342" checksum="D75D28A03246DD12" modified="2014-04-16" version="1" fragment="single">MPHTYGDEDLEVASEKYHESSDEDFDPNAAPAEDASSSEDEDHVTIEPAQRKGKRKAHQDEELDSGDEVTIQAARRKRSKKKGGKGNKDDDTELIISDDEGGEGGLVKTRAQRRTEGKEARPLARTEGATVDVDALWAQMMAAPLKPLQESKTQEANAPTQHTPVTNIQVSAEEEEQLTVKKTFTFAGQDTTEEKQIPRSQLDKYLKDGWKQAEATPAAESPAHSSSSQPDSKIRRPLRRPSRFDPNPTGYVRALAPEFQLSWPRTSTRPEPETAADPDAAALPKKAEKTQKLNVVDKSRMDWTGFVDKEGIAEELDTHGKTKEAYLGRMEFLAGVEARREEERRNAKIKAVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z189</accession>
    <name>W6Z189_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">IMS import disulfide relay-system CHCH-CHCH-like Cx9C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_38606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964028">
        <property type="protein sequence ID" value="EUC43473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690012.1">
        <property type="nucleotide sequence ID" value="XM_007691822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z189"/>
    <dbReference type="STRING" id="930090.W6Z189"/>
    <dbReference type="GeneID" id="19123509"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38606"/>
    <dbReference type="eggNOG" id="ENOG502SBX9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_188562_2_0_1"/>
    <dbReference type="OrthoDB" id="3821113at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034595">
        <property type="entry name" value="NDUFAF8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34561">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34561:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC43473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6794" checksum="93460D9AF01F134F" modified="2014-04-16" version="1">MPGRTRPIDKLATAAAKCSKESSLYGKCILADYNNVRKDMCVNEFMKLKECYLKAYKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1D1</accession>
    <name>W6Z1D1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aldehyde dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_95216</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687957.1">
        <property type="nucleotide sequence ID" value="XM_007689767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1D1"/>
    <dbReference type="STRING" id="930090.W6Z1D1"/>
    <dbReference type="GeneID" id="19128607"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95216"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_1_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019413">
        <property type="term" value="P:acetate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07091">
        <property type="entry name" value="ALDH_F1-2_Ald2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000011">
        <property type="entry name" value="ALD5p Mitochondrial aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000001">
        <property type="entry name" value="Mitochondrial aldehyde dehydrogenase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="10">
        <location>
            <begin position="29"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="499" mass="54304" checksum="3DFA6800B719562B" modified="2014-04-16" version="1">MSETSVKLSTPQTGEYEQPTGLFINNEFVKSVDGKTFEVINPSTEEVICSVAEATEKDVDIAVAAARKAFNGPWRKETPENRGRLLVKLAELFEKNADLLAAVEALDNGKAFNMARSVDLPAAAGCLRYYGGWADKIEGKIVDTTPDTFNYIRKEPIGVCGQIIPWNFPILMWSWKIGPAIAAGNTVVLKTAEQTPLSAYVACKLIKEAGFPPGVINVITGFGKVAGAAISSHMDVDKVAFTGSTVVGRQIMKAAAGSNLKKVTLELGGKSPNIVFADADLDEALNWVNFGIYFNHGQTCCAGSRVYVEESIYDKFIQRFRERAAQNAVGDPFAKDTFQGPQVSQLQFDRIMSYIEDGKKSGATVETGGKRKGDKGYFIEPTIFSNVTEDMKIQQEEIFGPVCTISKFKTKEEVIKIGNSTTYGLAAALHTTNLKTAIEVANALKAGTVWVNTYNTLHWQLPFGGYKESGIGRELGEAALDNYTQTKTVSIRLGDMLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1Q9</accession>
    <name>W6Z1Q9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_26212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687813.1">
        <property type="nucleotide sequence ID" value="XM_007689623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1Q9"/>
    <dbReference type="GeneID" id="19120898"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26212"/>
    <dbReference type="eggNOG" id="ENOG502S8FZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070842_0_0_1"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045030">
        <property type="entry name" value="LYSM1-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932">
        <property type="entry name" value="LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932:SF31">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="118"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="264" mass="29310" checksum="C9C164C4EB498AA2" modified="2014-04-16" version="1">MSEACCTCATLLTSIPPTYDEKTEKPSQFERRLDCCGRAICARCLTDNPRFQNYCPFCQIATGPSALPPQGLRDPPTYSPPDEQQLVDDELPPYSARNSLQAPSEKSKAKGEDAPDVLHFVDQNNDSVRSLSLRYGVPADALRRTNNLFADHLLAARRTILIPGEYYKGGVSLSPRPLEGEEEEIKKTKLRKFMVKCKVAEYDVALLYLEQANYNLEQAITAFKADEEWEKGHSLEAAKKGKSKASQSLGRKKWGFGGLTGQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2I5</accession>
    <name>W6Z2I5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="13">FBP aldolase</shortName>
            <ecNumber evidence="5 13">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_99553</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 13"/>
    <dbReference type="EMBL" id="KI964016">
        <property type="protein sequence ID" value="EUC43933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689582.1">
        <property type="nucleotide sequence ID" value="XM_007691392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2I5"/>
    <dbReference type="STRING" id="930090.W6Z2I5"/>
    <dbReference type="GeneID" id="19129491"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99553"/>
    <dbReference type="eggNOG" id="KOG4153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036923_0_0_1"/>
    <dbReference type="OrthoDB" id="35652at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904408">
        <property type="term" value="F:melatonin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061621">
        <property type="term" value="P:canonical glycolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00946">
        <property type="entry name" value="FBP_aldolase_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000013">
        <property type="entry name" value="Class II fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006628">
        <property type="entry name" value="PRK09197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559:SF0">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="268"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="289"/>
            <end position="292"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC43933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="361" mass="39466" checksum="2D8338BF24926436" modified="2014-04-16" version="1">MVQASEVLSRKTGVIVGDDILALFKHAQSEGYAIPAINVTSSSTVVAALEAARDAKSPIILQLSNGGAAYFAGKGVANGKQEASIAGSIAAAHYIRSIAPAYGIPVVLHTDHCAKKLLPWLDGMMDADEAYFKAHGEALFSSHMIDLSEEPKEWNIATTKKYLERAAPMKQMIEMEIGITGGEEDGVNNEDVDNNSLYTQPEDIYDIYKELSAVSPLFSIAAGFGNVHGVYKPGNVKLRPELLQKHQAYVKEKTNSKEDKPVFLVFHGGSGSSVDDFRQAISYGVVKVNLDTDMQWAYLSGIRDYIQSKSGYLQTQVGNPDGDDKPNKKYYDPRVWVREGEKSMSQRIKVALDDFYTAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2W8</accession>
    <name>W6Z2W8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_6343</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964007">
        <property type="protein sequence ID" value="EUC44270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2W8"/>
    <dbReference type="GeneID" id="19124929"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6343"/>
    <dbReference type="eggNOG" id="KOG1153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_4_1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886574" description="Peptidase S8/S53 domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="9">
        <location>
            <begin position="156"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC44270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="470" mass="49270" checksum="B88CCE374FA37ADF" modified="2014-04-16" version="1">MKSFFTLTASLLAASSSLVAAFPSPGFINKNTLPSNHSTEVKEYIVTWWRNETVPEPIERYMDALELNKNGDAILFESSPGVNPRVVILKMCDEHAAIFKSMAEINVVEEKAQVKSFVEQRDGSPWGLERISSAQGPSGSPQGQDFTYSFNDSSLGSGVDIYVIDTGMRTSHAVFTGRAIQGFTATGSFVDGDGHGTHVAGTAGGAKFGVAQGANLIEVKVLGDDGSGASSDTIRGMDWVIARHNKRKTEPGFIGSIMSMSWGLQGFANSVDEVITGASEAGIHVSVAAGNDGQDACGSTPAHLGGANSNIVTVGSVNINNKVSSFSNNGRCVDIYAPGEQILSSWSTGDNVINFLSGTSMACPHTTGVMAVLMTQDVAGLGQNPAALKAKLLATARKNDISGNLAGSANLLLSNGVNGNVAQRLVKNYVVPDHSGLNGSPAARAAARMAESAPIDKRFSLHSRDVQLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3A3</accession>
    <name>W6Z3A3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_27420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964009">
        <property type="protein sequence ID" value="EUC44188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689263.1">
        <property type="nucleotide sequence ID" value="XM_007691073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3A3"/>
    <dbReference type="GeneID" id="19121118"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27420"/>
    <dbReference type="HOGENOM" id="CLU_799220_0_0_1"/>
    <dbReference type="OrthoDB" id="10302652at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="347" mass="38242" checksum="56E0AF2DA23D10C7" modified="2014-04-16" version="1">MPYARRPLCLPAPTPDARASQAPSRDPPTAAAWLLPPACLPTLLATATTTSTTTVYVRRVCLRLKWRPPRLHEWGSRRRPWGGQGKRSFYFQTLPSAFACCCCYCPRRRMPNHHTRALTHARGGLFLTCLVSSCQIIIILVPFPSMGSRDPTVLPLLPWPLYAVAVVSIPAPSTIACWPRPCYSNAPCDLHFAPAACTHNPRPQITARTRRGPIGRVTDPFSHSFAACCVWCVRVCVCAPCPRVQFTAASRPFEQLHHSAAPPSAPPLAAAAGESRKTLAPNVAYGDWPMHARIPPTAMYRTRDRPRDARHGNAPREQRHGRPGPIAADRPWDVASYLLLRAPSAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3F8</accession>
    <name>W6Z3F8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_104230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964071">
        <property type="protein sequence ID" value="EUC42164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691336.1">
        <property type="nucleotide sequence ID" value="XM_007693146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3F8"/>
    <dbReference type="GeneID" id="19118468"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104230"/>
    <dbReference type="eggNOG" id="ENOG502R8MW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1562607_0_0_1"/>
    <dbReference type="OrthoDB" id="4158258at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="179" mass="19099" checksum="3CB8AEF151C8BC15" modified="2014-04-16" version="1">MTSAKSKASESGTSKNDTAGTSTASHDTPPAYDGSSTSEPPPTYESVGRALTALSQGDPDELILVPFVTRTVGFSIHNYNPFSHKQGEIRQSIVTRRMKRSHYLAHYVKDMNGNFVGTSTPAVDAALVFVPGKSSPEDSLRQVNEVAFKVQRLRGDGIGDWGKPLQDHPAGYGGGGMAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3N7</accession>
    <name>W6Z3N7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_93104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687125.1">
        <property type="nucleotide sequence ID" value="XM_007688935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3N7"/>
    <dbReference type="GeneID" id="19128205"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93104"/>
    <dbReference type="eggNOG" id="ENOG502QV4K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008719_1_3_1"/>
    <dbReference type="OrthoDB" id="4525710at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF25">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="566" mass="63708" checksum="D9ECB84F229B8B53" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4T9</accession>
    <name>W6Z4T9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_97430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688760.1">
        <property type="nucleotide sequence ID" value="XM_007690570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4T9"/>
    <dbReference type="GeneID" id="19129059"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97430"/>
    <dbReference type="HOGENOM" id="CLU_3129635_0_0_1"/>
    <dbReference type="OrthoDB" id="10303749at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="50" mass="5675" checksum="0A08638CE8C2FAD9" modified="2014-04-16" version="1" fragment="single">PPWSRTRHSAGVMTYSSPSPGCACRVRKTMSRYRMDMAHARMSPSGYDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z545</accession>
    <name>W6Z545_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_5681</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963991">
        <property type="protein sequence ID" value="EUC45105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688375.1">
        <property type="nucleotide sequence ID" value="XM_007690185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z545"/>
    <dbReference type="STRING" id="930090.W6Z545"/>
    <dbReference type="GeneID" id="19124700"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5681"/>
    <dbReference type="eggNOG" id="KOG0088">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1245147_0_0_1"/>
    <dbReference type="OrthoDB" id="10002389at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24529" checksum="D0BB56612106D690" modified="2014-04-16" version="1">MLRSKKSESHRIVVLGQSEVGKTCFVDMFLEGRHFISHSAVSSTPSSRHISHSGTSFTLSPRDLDLTGPLSSGYLTIVDEYLRTADGIVLLYDITCKSSFASVTHEFYVHAWTCRDDIGAKEVGGHVTKKRFGCVLVGNKRDVIVGEDAAKRQVDKNMAEQWASSQGAKHFEITANERSEVEEVVKALVDSIARARRMDQRDKANGATNGRGSVMRLLKRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z671</accession>
    <name>W6Z671_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_36964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688189.1">
        <property type="nucleotide sequence ID" value="XM_007689999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z671"/>
    <dbReference type="STRING" id="930090.W6Z671"/>
    <dbReference type="GeneID" id="19123151"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36964"/>
    <dbReference type="eggNOG" id="ENOG502SFH4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042426_1_0_1"/>
    <dbReference type="OrthoDB" id="5405654at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42053">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42053:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="247" mass="26543" checksum="E0C8047E615E9F53" modified="2014-04-16" version="1">MAATDSKPALSTLKTPMSATYPSELRSPMVTSATTPIFASIKREDSDIKTPITPPTAYLEFLKNLSPVLSSPMSTGTSCRFVFGESRPTSVTSSASSASFTSTSAPSDKDSPATSRSNSCGSCDTSKDEAKEPMSAPPTKVQTVTIPPPSPFRRHSARTPRLYIPQSPYSPATVRSPASAKSIQSPYSAVSSPKTWEADKKTGRSRRVSVREVVTRTVTYSRTPVDAKAPHFPQIDPAPRGKRRKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6F0</accession>
    <name>W6Z6F0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_90521</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686186.1">
        <property type="nucleotide sequence ID" value="XM_007687996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6F0"/>
    <dbReference type="GeneID" id="19127702"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90521"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_82_4_1"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="552"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="709"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="1038"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1002"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1005"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="1101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1175" mass="130359" checksum="8660A97F814C319B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6I2</accession>
    <name>W6Z6I2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfite efflux pump SSU1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_90512</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Sulphite efflux pump required for the secretion of sulphite as a reducing agent. In the presence of sulphite, cystine in keratin is directly cleaved to cysteine and S-sulphocysteine, and thereby, reduced proteins become accessible to hydrolysis by a variety of secreted endo- and exoproteases. Excretion of sulphite mediated by an efflux pump also represents a detoxification pathway for dermatophytes during infection of the epidermal stratum corneum, hair and nails, which are rich in cysteine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686209.1">
        <property type="nucleotide sequence ID" value="XM_007688019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6I2"/>
    <dbReference type="GeneID" id="19127700"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90512"/>
    <dbReference type="eggNOG" id="ENOG502QT02">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030057_6_1_1"/>
    <dbReference type="OrthoDB" id="1099at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000319">
        <property type="term" value="F:sulfite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09318">
        <property type="entry name" value="TDT_SSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.150:FF:000004">
        <property type="entry name" value="Malic acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051629">
        <property type="entry name" value="Sulfite_efflux_TDT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686:SF1">
        <property type="entry name" value="SULFITE EFFLUX PUMP SSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00056100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="365" mass="40397" checksum="382586980B2171B5" modified="2014-04-16" version="1">MGTGIVAVLLHTLSNLYQSYHDLLRTLSIVFFILNVGIFSVIFAISVLRYTLFPATWTLMLRHPVQSLFLGTMPMGFSTIVNMFVAICVPAWGGSAPYVAWGMWWLDVVISVACCLWLPFQMMTQHRNQHEKMTAAWLLPIVACIVAAASGGLVASVLPNDNHALITIITSYVLWSMGLPLALVILTMYFHRLTIHHLPPKEVIVSVFLPLGPMGQGGYAAMQLGIQASKVFPRTQTLHPLAGGILYVLGWITALVLWGFGLVWLFFAVASISRSRFPCNLGWWGFTFPIGVFTMSTITMGQEMPSAFFRIFGTMLAVGVILLWLLVAASTVKNVLYGDIFVAPCLKEMEKRAAAEAEMRAYRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z717</accession>
    <name>W6Z717_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_36684</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963981">
        <property type="protein sequence ID" value="EUC45588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687877.1">
        <property type="nucleotide sequence ID" value="XM_007689687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z717"/>
    <dbReference type="GeneID" id="19123086"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36684"/>
    <dbReference type="HOGENOM" id="CLU_2072726_0_0_1"/>
    <dbReference type="OrthoDB" id="3671183at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="126" mass="14151" checksum="5CE952BCE37A496F" modified="2014-04-16" version="1">MDHLDADRLLVQGQFGPDCSLLTRSRVSQQLDQAGGYGMNLLAVKTDGPHTSYTSHGQLWYMSRIVESTMGSCLQPVLPAVYLTLRAETRASYWLNVDLNACTFHVLSFFPSASGERRLDYRYTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z736</accession>
    <name>W6Z736_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_95169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963981">
        <property type="protein sequence ID" value="EUC45608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687903.1">
        <property type="nucleotide sequence ID" value="XM_007689713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z736"/>
    <dbReference type="GeneID" id="19128600"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95169"/>
    <dbReference type="HOGENOM" id="CLU_172675_0_0_1"/>
    <dbReference type="OrthoDB" id="3693038at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="111" mass="12834" checksum="A33E8F45E8DD5E7F" modified="2014-04-16" version="1">MPCTTIIITTTQTLTSPSTAANHKSLEKRITALSIKIATDRANRREMLPLDHTTWKREDPWSADLERFQIELEELWIEVRGQTLEFKTVWVDAVEKMYADEIGIWRASGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z774</accession>
    <name>W6Z774_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_100910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964030">
        <property type="protein sequence ID" value="EUC43409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690093.1">
        <property type="nucleotide sequence ID" value="XM_007691903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z774"/>
    <dbReference type="GeneID" id="19117768"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
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    </evidence>
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        </source>
    </evidence>
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</entry>
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        <recommendedName>
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        <alternativeName>
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        </alternativeName>
    </protein>
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        <name evidence="15" type="ORF">COCMIDRAFT_7108</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="15 16">ATCC 44560</strain>
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    </reference>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
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    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00176">
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    </dbReference>
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        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="1347"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="1702"/>
            <end position="1850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="73"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
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            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="716"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1870"/>
            <end position="1893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00073046"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00081329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43479.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1937" mass="213356" checksum="E9A7BC758674B460" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z878</accession>
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        <recommendedName>
            <fullName evidence="9">NF-kappa-B inhibitor-like protein 1</fullName>
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        <name evidence="7" type="ORF">COCMIDRAFT_110244</name>
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            <taxon>Dothideomycetes</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">ATCC 44560</strain>
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    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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        </subcellularLocation>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
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        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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        </location>
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        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
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    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC39901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="41291" checksum="25BBBC103672C660" modified="2014-04-16" version="1">MEDQASGVTEDGLYAKAKASPFHFKSGSTRRSRCRDNEDKHEDTDKHSRKRHRADQDEDTRREHRHSRRKHKHKHRAHHDRHPTSTRDGTYYDPDHRHRESLFDNLEESGAASPGKAPEDAFRESLFDALADDEGAAYWEGVYGQPVHIYSDKKPGADGKLERMTEDEYADYVRTKMWEKSHQHILEEREAKERARQKRKAQRSQLDDELEREEAERENIRRRMEESLCRGEERKKVKEAEAAWHSYTAKWDGLKNAQHSSDGAAIKAHDMIPWPVVSGQAKHVSKDEIERFLRASKSWREDSAALLKAERVRWHPDKMQQRFREHMDADTMKLVTAVFQIIDQLWNNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z885</accession>
    <name>W6Z885_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear condensin complex subunit 3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_4678</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687260.1">
        <property type="nucleotide sequence ID" value="XM_007689070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z885"/>
    <dbReference type="STRING" id="930090.W6Z885"/>
    <dbReference type="GeneID" id="19124335"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4678"/>
    <dbReference type="eggNOG" id="KOG2025">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004446_0_1_1"/>
    <dbReference type="OrthoDB" id="27187at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="9">
        <location>
            <begin position="647"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1017"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1062"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1088"/>
            <end position="1103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC46170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1140" mass="127148" checksum="53A2AD514D038C71" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8G6</accession>
    <name>W6Z8G6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_109969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964213">
        <property type="protein sequence ID" value="EUC39981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693493.1">
        <property type="nucleotide sequence ID" value="XM_007695303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8G6"/>
    <dbReference type="STRING" id="930090.W6Z8G6"/>
    <dbReference type="GeneID" id="19119525"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109969"/>
    <dbReference type="eggNOG" id="ENOG502QQ8X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_22_1"/>
    <dbReference type="OrthoDB" id="1577640at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="326" mass="35397" checksum="6ADDAA16910BB92A" modified="2014-04-16" version="1">MPRQPRREEYTVGWVCALPIESAAAKLMLDEEYDPPLLEPGETCDDVYSTGSIAGHNVVIACLESGRTGTNSAATLATRMQAMFKGIRFGLMVGIGGGVPSEQKDIRLGEVVVSVPGGTFAGVVQYDMGKTTPGNNIRTGNLNSPPRVLLSAVNVLKTDALLGRSKLLNILSKTQDIPSLRRCESSTDVLYDASYNHGNDSTCENCRSDKQLVRYQRRRGEEVVVHHGTIASGNQVMKSAAERDKISQKLGGVLCFEMEAAGLMNSFPCLVIRGISDYADSHKNDQWQGYAAATAAAYARELLLKIQPTRVMETARVEDVINDPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8U6</accession>
    <name>W6Z8U6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964197">
        <property type="protein sequence ID" value="EUC40111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693372.1">
        <property type="nucleotide sequence ID" value="XM_007695182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8U6"/>
    <dbReference type="STRING" id="930090.W6Z8U6"/>
    <dbReference type="GeneID" id="19121766"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30896"/>
    <dbReference type="eggNOG" id="ENOG502RXB4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009827_2_0_1"/>
    <dbReference type="OrthoDB" id="3034343at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="2">
        <location>
            <begin position="182"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="525" mass="59328" checksum="901B4CB59FC67A58" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8V9</accession>
    <name>W6Z8V9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein MAK16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_109588</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MAK16 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC40126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="entry name" value="Protein MAK16 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04874">
        <property type="entry name" value="Mak16"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="6">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="298"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="315"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="340" mass="39151" checksum="4E6F951492B852C1" modified="2014-04-16" version="1">MASDDLVWSIIGTDFCSFKLKTTKDQTFCRNEHNVSGYCSKQSCPLANSRYATIRSDPATGNLYLYIKAIERAHLPSQWWEKIKLPKNYAQALELVDQHLAYFPKFLVHKNKQRLTRLTQVNLRIRRLAKEEERLGERLVPRLAPKVRRREEGRERKALAAAKVERAIERVLIERLRSGAYGDRPINVEPNVWKRVMRGLEKEGQLKGDQDLDDGIEDEDEENEYEQEMENGVGEVEYVSDIEGESDDEMEDFEDWIGGQSPDDGTSGEDEESGSDEEEEDESEDEDTEALKKTLANLKRKRPAGPPPKPKKKPSKDSKGPKRKIEYEMERAPAREAMHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9E0</accession>
    <name>W6Z9E0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PDZ GRASP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_65731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9E0"/>
    <dbReference type="STRING" id="930090.W6Z9E0"/>
    <dbReference type="GeneID" id="19125007"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_65731"/>
    <dbReference type="eggNOG" id="KOG3834">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025095_0_0_1"/>
    <dbReference type="OrthoDB" id="3318at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000026">
        <property type="entry name" value="Golgi reassembly stacking protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007583">
        <property type="entry name" value="GRASP55_65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024958">
        <property type="entry name" value="GRASP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893">
        <property type="entry name" value="GOLGI REASSEMBLY STACKING PROTEIN GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893:SF0">
        <property type="entry name" value="GRASP65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04495">
        <property type="entry name" value="GRASP55_65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51865">
        <property type="entry name" value="PDZ_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ GRASP-type" evidence="6">
        <location>
            <begin position="39"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ GRASP-type" evidence="6">
        <location>
            <begin position="128"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="276"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="377" mass="39500" checksum="C28B6B52B7F091DB" modified="2014-04-16" version="1" fragment="single">MSVFGALNRFISRLDAAPLPSDTHAQQHHHHQSSTNGAYGFQVLRNANLEIPLEPWFDFVIGINGRTIDNPDPNLFATEVRNCAGTTISLGIFSAKGQKIREVYLQIPADQPTLGIALQWSPLAVAEDVWHILDVAPNSPADTAGLLPYGDYVIGSPEGLVRGESGLGELVEDFLNRPLRLYVYNHEYNVTRPVTITPTRNWGGEGALGCVLGFGALHRIPAGLDEPPPAPGETFFSAGDASGSTSFDEKRPLVSSMGIPAQSGAPAELFVPANMALPAKSPPPQGTAPPPKKKGRAHHVASSATGGGGGLDDYFKEGEQKSLEQDYAPTKGSGVPPPPKAGGPPRGPPKSGSASRTGTPLQGGGDAESATGAETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9K5</accession>
    <name>W6Z9K5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_41281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="762" mass="86153" checksum="5D85D7E654FD8F50" modified="2014-04-16" version="1"> </sequence>
</entry>
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    <accession>W6ZA19</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="22"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="67" mass="7070" checksum="44957D1A955F2BF7" modified="2014-04-16" version="1">MTKSNVEAAKRAAGQQAAVDHSDANSSYFSISSGIIVVLLKAIKAPVAVYFGMQDDSIMVRTADGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA74</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
    <sequence length="240" mass="27174" checksum="A129A444CA7487A7" modified="2014-04-16" version="1">MSRRNSAMYTTHPLTAQFDSAKFMVGGGVAIFHLATGRVILCSYEQHGRKVYFLPKGRRDAGEESGTGAEREGYEESGYRNRLLPLPTRHCQPQAHPRVHAATHTAEPVLLQLMPLREYQYVVYWYIAETLPPSLEGDLETEPGSPYKLPPRYPQNLSLRERIAMEPQGYEPRHHEGTGVDNMERQFKSELCSVEDAIKKLGQGHMMGEAMADVVRKGWEGIQKRFEMEDAATQQSPEAV</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690786.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="177" mass="18208" checksum="D09AA0DA5475E9A8" modified="2014-04-16" version="1" fragment="single">MASEQAYSPAPPPSPRLPPPPSSPHPTHLQAPQISPRRFAVQPPLLNTTLAPPPPSGPAYLHGSTPVTASSLSLPFSPSLTPSTYAPSPVAAASPMAMRGSAPAAPYNPQQWSRGGSVNGQHVQHSQISVPSRLHDVTGMEASMPSPPPPYSPGQNPNISQSLSTSTTSSPQPAANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAL0</accession>
    <name>W6ZAL0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_91721</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48096"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11991"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61897"/>
            <dbReference type="EC" id="2.1.1.319"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:48097"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="1"/>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686656.1">
        <property type="nucleotide sequence ID" value="XM_007688466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAL0"/>
    <dbReference type="STRING" id="930090.W6ZAL0"/>
    <dbReference type="GeneID" id="19127935"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91721"/>
    <dbReference type="eggNOG" id="KOG1499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017375_6_0_1"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000003">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000016">
        <property type="entry name" value="Protein arginine methyltransferase RmtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF123">
        <property type="entry name" value="RIBOSOMAL PROTEIN ARGININE N-METHYLTRANSFERASE RMT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="9">
        <location>
            <begin position="307"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC46833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="507" mass="56679" checksum="BE250A8CE6ADCB15" modified="2014-04-16" version="1">MSDTDSDTASSVGSIVEDASEPDTSTFKDLFSDRQWTRVSDMIAHDKTEHGFDLTETIKGLGPDADEITIIKLINYLRFEAQKGTDPKSIKVTLDDLSSDKYLQPVLEDDALLFELGDLMPNDDANAIDYDEYEAKLQKDMPEDFSKIKLVNDRDQDYFESYKGNSIHREMIEDRVRTEGYRDFIEKNADVFAGKTVMDVGCGTGILSLFCARAGAKKVFAVDNSGIAVRAKEIIEKNGYQDRIELIQGRAEDFNTQRRIGKEKVDIIISEWMGYGLLFEGMLDSVLRARDMYLKPDGIMVPSHCNIRLAPISDAEWIADSTGEKFWKDIYGFDFSPMIPGGLLNTHEIGVFDVPEKSLCGSANSHLLEMKTVSIKDLSFNIPLRMTLDRDIKSLEAIAIWFDTIFIHPGSSQDIKTIDNVDWGKNGIPGLGFSTGPSNTPTHWHQAVLLLDPEVAKKQTFKKGTVLEGTLTYAKEKGDDRGITVTVEWKGNGEQGDVEGKVERTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBA2</accession>
    <name>W6ZBA2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_97431</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688742.1">
        <property type="nucleotide sequence ID" value="XM_007690552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBA2"/>
    <dbReference type="GeneID" id="19129060"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97431"/>
    <dbReference type="eggNOG" id="ENOG502SJ0Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017443_2_1_1"/>
    <dbReference type="OrthoDB" id="3266505at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF9">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="215"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="588" mass="65848" checksum="368B91275AFBFCCE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBE2</accession>
    <name>W6ZBE2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">guanosine-diphosphatase</fullName>
            <ecNumber evidence="5">3.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_27005</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.42" evidence="5"/>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688727.1">
        <property type="nucleotide sequence ID" value="XM_007690537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBE2"/>
    <dbReference type="STRING" id="930090.W6ZBE2"/>
    <dbReference type="GeneID" id="19121043"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27005"/>
    <dbReference type="eggNOG" id="KOG1385">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010246_4_0_1"/>
    <dbReference type="OrthoDB" id="6372431at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004382">
        <property type="term" value="F:GDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="598" mass="65795" checksum="4CB24E228205119D" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="Han J."/>
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                <person name="Ciuffetti L.M."/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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    </feature>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC31</accession>
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            <fullName evidence="5">Hydrophobin</fullName>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964111">
        <property type="protein sequence ID" value="EUC41281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692220.1">
        <property type="nucleotide sequence ID" value="XM_007694030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC31"/>
    <dbReference type="GeneID" id="19118890"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106602"/>
    <dbReference type="HOGENOM" id="CLU_2385825_0_0_1"/>
    <dbReference type="OrthoDB" id="3694789at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886695" description="Hydrophobin" evidence="2">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12072" checksum="7F52C49037D0AAA5" modified="2014-04-16" version="1">MKLFVTLPLAFAALVVSTPTKLNSRLDLGKVQDALEARQAGGGPGLPTVTQAPSISPPPPVSQPIVCSCPKILGRCIIDATCGILSLYGGLYRFYVEFKLERYIQVRLRVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC35</accession>
    <name>W6ZC35_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_84631</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684109.1">
        <property type="nucleotide sequence ID" value="XM_007685919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC35"/>
    <dbReference type="GeneID" id="19126498"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84631"/>
    <dbReference type="eggNOG" id="ENOG502QR6D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013783_3_0_1"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000015">
        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF35">
        <property type="entry name" value="PEPTIDASE S53 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889899" description="tripeptidyl-peptidase II" evidence="16">
        <location>
            <begin position="22"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="17">
        <location>
            <begin position="212"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="545"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="546"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="580"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC49362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="616" mass="67168" checksum="6C06CC3DD938D279" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC78</accession>
    <name>W6ZC78_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcriptional regulatory protein RXT2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_89870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685961.1">
        <property type="nucleotide sequence ID" value="XM_007687771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZC78"/>
    <dbReference type="STRING" id="930090.W6ZC78"/>
    <dbReference type="GeneID" id="19127565"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89870"/>
    <dbReference type="eggNOG" id="ENOG502S5XA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022436_0_0_1"/>
    <dbReference type="OrthoDB" id="441210at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039602">
        <property type="entry name" value="Rxt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013904">
        <property type="entry name" value="RXT2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28232">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RXT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28232:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RXT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08595">
        <property type="entry name" value="RXT2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="46"/>
            <end position="174"/>
        </location>
    </feature>
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        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="198"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="632"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="532"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
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        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="641"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="664"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="712"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF08595"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="761" mass="83716" checksum="950CCAF7B214D72A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCA9</accession>
    <name>W6ZCA9_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_96611</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_96611"/>
    <dbReference type="HOGENOM" id="CLU_1320787_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="208" mass="24413" checksum="5F445739B75F6D15" modified="2014-04-16" version="1">MRITAILWAAKARTATPIPRRMQRDQVRKLLGLSDQQWPIFLRISLAVCQDYAGAKLSDISPPEKEEMMDRIRSVLHQEGLPPLDDEAIEWRISKCLPELRVKKRDIEHCHSWEATTETKFPRQLLREAVLAHIDKIPTKNLCYWTQIPQDVRQDVVEEANRRLAEKGMPVVDEAALLYRLRKYMNHWIKSGLVQDTKESRRHNDKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCZ4</accession>
    <name>W6ZCZ4_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_34586</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    </dbReference>
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    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502QWAA">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024810_3_1_1"/>
    <dbReference type="OrthoDB" id="18453at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GCR1-cAMP_receptor"/>
    </dbReference>
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        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05462">
        <property type="entry name" value="Dicty_CAR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GCR1CAMPR"/>
    </dbReference>
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        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="6">
        <location>
            <begin position="13"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="500" mass="56704" checksum="417A8B039B984C95" modified="2014-04-16" version="1">MAAKLPYNKALAFVVATRISSILSVVGSSIIVSTFIAFPFFRKPINRLVFFATLGNILTNVATLMSNSVLPAPGEPASGLCEFQGLLIQWFMVADSFWVLCMATNVFLVFFYGYDAQQLRHLEKWYFAFSYGVPCIPVIAYVVLSRTGHPIIGSATLWCWVSFDVEWMRIAFFYVPAWVTILAAVTIYSVTGYRIWQKQVELRFFSRDSNQFVTVRDVSDERENVGDISSGRNNIVVTTQIECDIQQQGDMFRSVSPDPDCISINSFSSTQRLSRIRGPDELVSRPLHDASQTRISRLLLEDVEAQLNFHHPPPSRNNYIATIITTSPPLRPMNRPPTAMSKPLPAAKRTPEGHAAAMAYFYVAFLMFLALFVVWLPSSINRMYQFTHKDRPSFALNILSATVLPLQGAWNAIIYIFTTRAECRRAWGMVVEKITGRYAQYQPWRELSVKEMTSSQVTRESAVDVEMGDIFRHDMRACQIKSPKNGHVKDDDRCSKLISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZET6</accession>
    <name>W6ZET6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_87051</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684967.1">
        <property type="nucleotide sequence ID" value="XM_007686777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZET6"/>
    <dbReference type="GeneID" id="19126976"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87051"/>
    <dbReference type="eggNOG" id="ENOG502S8TF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034677_0_0_1"/>
    <dbReference type="OrthoDB" id="5778525at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF27">
        <property type="entry name" value="TRANSCRIPTION FACTOR AP-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="115" mass="12291" checksum="B9657A315F9A3541" modified="2014-04-16" version="1">MCVKLLPAILLVHVGIVAVSLVAVLSLAELYGGAVTATQPSMGLLNMTVLHGGHRNHLPATRQHGISIWAESMALDTRQGNLEYCLDIASTPVDVHLHADSTDTEVSAYRLMHAL</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="7"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0677">Repeat</keyword>
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        <location>
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            <end position="365"/>
        </location>
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        <location>
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            <end position="467"/>
        </location>
    </feature>
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        <location>
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            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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        </location>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="635" mass="71819" checksum="29990D35C4442385" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFE4</accession>
    <name>W6ZFE4_COCMI</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_4722</name>
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        <dbReference type="NCBI Taxonomy" id="930090"/>
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            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="GeneID" id="19124352"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4722"/>
    <dbReference type="eggNOG" id="ENOG502SPFH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122014_0_0_1"/>
    <dbReference type="OrthoDB" id="3927857at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886987" evidence="1">
        <location>
            <begin position="20"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="205" mass="22603" checksum="90A1EC1F15167C8B" modified="2014-04-16" version="1">MRYLSIGAAVASLLASSTAFGLSPQEVLDKNSPRILDETGIDPCTLVDSPKANASVQLGSWLECAVNGFYPFPANKNWPEGHATSFSKDIRFTFNDTHYDFEGSRRLYNTFNATLGVAFAPFKHGFINTLGIPNANGDKGGFVYMIGWAGGFQTRIQRDVYFTNAAFAVVKEVEGERKIVEFRESSNIPNTAILPPPVEWTCEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFH1</accession>
    <name>W6ZFH1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_93273</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687240.1">
        <property type="nucleotide sequence ID" value="XM_007689050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFH1"/>
    <dbReference type="GeneID" id="19128239"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93273"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_7_2_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886992" evidence="4">
        <location>
            <begin position="19"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="22"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="6">
        <location>
            <begin position="460"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="545"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="588"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="608" mass="65981" checksum="C03D8604E935B44B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFK2</accession>
    <name>W6ZFK2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sodium/calcium exchanger membrane region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_32140</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682859.1">
        <property type="nucleotide sequence ID" value="XM_007684669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFK2"/>
    <dbReference type="GeneID" id="19122033"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32140"/>
    <dbReference type="eggNOG" id="KOG1397">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008721_4_0_1"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000011">
        <property type="entry name" value="Vacuolar calcium ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000021">
        <property type="entry name" value="Vacuolar calcium ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="516"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="215"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="452"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="74"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC50622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="606" mass="65552" checksum="20380040C3CA1AC0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFS9</accession>
    <name>W6ZFS9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_35989</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3R)-atrochrysone 2-carbonyl-[ACP] + H2O = (3R)-atrochrysone 2-carboxylate + holo-[ACP] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:64236"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:20479"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:234107"/>
            <dbReference type="ChEBI" id="CHEBI:234110"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:64237"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963967">
        <property type="protein sequence ID" value="EUC46369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687103.1">
        <property type="nucleotide sequence ID" value="XM_007688913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFS9"/>
    <dbReference type="STRING" id="930090.W6ZFS9"/>
    <dbReference type="GeneID" id="19122912"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35989"/>
    <dbReference type="eggNOG" id="KOG0813">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048478_1_3_1"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07722">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000328">
        <property type="entry name" value="Lactamase beta 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000041">
        <property type="entry name" value="Metallo-beta-lactamase domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047921">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="WHD_BLACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="31"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC46369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="275" mass="30316" checksum="06B3235C992274F5" modified="2014-04-16" version="1">MVDALVPLPEIEKLSDRVIRVLGGNPGKVSSTNTYVVGRGASRLLIDTGEGRPQWIASVKSLLSKENIAIEKVLLTHWHLDHIQGVPDLLEHAPNTKVYKKDPHSDWLPIADGQKFETEGATLRAFFCPGHTTDHMAFVLEEENAMFTADNVLGQGTAVFEDLATYMNSLDAMSKQFGGRAYPGHGPVIDDGPAKIKEYISHRKQREQQVLDVLAADESGLGLSSMDIVKVIYKNYPESLWEPAERGILQILNKLKQEGKVTGDKTWSLSGKSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG49</accession>
    <name>W6ZG49_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP synthase subunit beta</fullName>
            <ecNumber evidence="14">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_2258</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="14"/>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC49005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684495.1">
        <property type="nucleotide sequence ID" value="XM_007686305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG49"/>
    <dbReference type="STRING" id="930090.W6ZG49"/>
    <dbReference type="GeneID" id="19120281"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2258"/>
    <dbReference type="eggNOG" id="KOG1350">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022398_0_2_1"/>
    <dbReference type="OrthoDB" id="14523at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18110">
        <property type="entry name" value="ATP-synt_F1_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01133">
        <property type="entry name" value="F1-ATPase_beta_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000001">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.170:FF:000004">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000026">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039072">
        <property type="entry name" value="ATPase_subunit_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="184"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC49005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="514" mass="55247" checksum="F1446E67D39375EE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG76</accession>
    <name>W6ZG76_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_663</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682653.1">
        <property type="nucleotide sequence ID" value="XM_007684463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG76"/>
    <dbReference type="STRING" id="930090.W6ZG76"/>
    <dbReference type="GeneID" id="19125027"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_663"/>
    <dbReference type="eggNOG" id="ENOG502R2RV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004278_0_0_1"/>
    <dbReference type="OrthoDB" id="5312224at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF6">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="516"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="545"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="574"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="605"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="9">
        <location>
            <begin position="65"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="805"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="857"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="899"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1138"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="828"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="949"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="968"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1034"/>
            <end position="1068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1174" mass="127970" checksum="F2BB2D63BF015986" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGX0</accession>
    <name>W6ZGX0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_85459</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684336.1">
        <property type="nucleotide sequence ID" value="XM_007686146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGX0"/>
    <dbReference type="STRING" id="930090.W6ZGX0"/>
    <dbReference type="GeneID" id="19126670"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85459"/>
    <dbReference type="eggNOG" id="KOG0941">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001858_0_0_1"/>
    <dbReference type="OrthoDB" id="5981550at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000003">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.130.10">
        <property type="entry name" value="Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain (AZUL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032353">
        <property type="entry name" value="AZUL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042556">
        <property type="entry name" value="AZUL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF8">
        <property type="entry name" value="HECT-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16558">
        <property type="entry name" value="AZUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
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        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF0">
        <property type="entry name" value="PURINE-URACIL PERMEASE NCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC49513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="545" mass="60223" checksum="B1C176A1BFDFCDA9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI76</accession>
    <name>W6ZI76_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_83792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683785.1">
        <property type="nucleotide sequence ID" value="XM_007685595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI76"/>
    <dbReference type="GeneID" id="19126332"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83792"/>
    <dbReference type="HOGENOM" id="CLU_2605881_0_0_1"/>
    <dbReference type="OrthoDB" id="3689690at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="79" mass="8755" checksum="3CA3D7C49909032F" modified="2014-04-16" version="1" fragment="single">IKASNDKRPGYSISCSFCLVVLLIVHYRQGQSLRVRLVPIVCLMVNSIIAQSTAEPKDLAVQHCDIFRRAHCGPNSTLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ01</accession>
    <name>W6ZJ01_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683518.1">
        <property type="nucleotide sequence ID" value="XM_007685328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ01"/>
    <dbReference type="GeneID" id="19120267"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22526"/>
    <dbReference type="eggNOG" id="ENOG502R8ZK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_909634_0_0_1"/>
    <dbReference type="OrthoDB" id="3680815at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="315" mass="35025" checksum="AC29B8CF7E61C48C" modified="2014-04-16" version="1">MLPSLLQQPSPSSSSSSSTSSSHAASTSTSSTSSTSSSGSNSSSAIPKPTTPSPFFAPLPHTTWSPTAAALALTRDIASMNTTILADLHGLSSIPRIYTTLFHRTREFAATVRHFASVVASGSWAAAACLLVDWGVHVLRHPGVGLERFLNSQRESLYWILDDALLRICVDMWDPPSEQRQQKEICEREEKAREVTRVVPWDQATGPIVRVLAKAQVLVPIWGQMDVEETRKWEVPIYEGAQADWFEVGWFRRSRQFLRESSRIHEIWRTVRRAGKGQLPAELANVIVEDVAAFEELPLGDLRELYFPTGKRVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJ46</accession>
    <name>W6ZJ46_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-lysine N-methyltransferase EFM6</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Elongation factor methyltransferase 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">EFM6</name>
        <name evidence="2" type="ORF">COCMIDRAFT_32622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="KI963926">
        <property type="protein sequence ID" value="EUC50055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683414.1">
        <property type="nucleotide sequence ID" value="XM_007685224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJ46"/>
    <dbReference type="STRING" id="930090.W6ZJ46"/>
    <dbReference type="GeneID" id="19122145"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32622"/>
    <dbReference type="eggNOG" id="KOG2793">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055721_2_1_1"/>
    <dbReference type="OrthoDB" id="407325at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03198">
        <property type="entry name" value="Methyltr_EFM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033684">
        <property type="entry name" value="EFM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF152">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EFM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="79"/>
            <end position="81"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="226" mass="25048" checksum="D4688301FF7A05E1" modified="2014-04-16" version="1">MLELDGFAVSQDLVPAAPIKSAGVSKVDFDGLLSPPLSLHEDLKNGCGGQLWPAGMVLSKYMLRKHRDDVAGKEIVELGAGGGLVGLAVAIGCNVDKPLHITDQIPMFDLMERNIALNGLESCVKASVYDWGEPTPSQLPSHPDIILAADCVYFEPAFPLLQQTLKDLIGENTVCYFCFKRRRRADLTFMKTARKMFDVQEVDDDPDKEVYSREKLFLYRISKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJZ5</accession>
    <name>W6ZJZ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_24325</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685659.1">
        <property type="nucleotide sequence ID" value="XM_007687469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJZ5"/>
    <dbReference type="STRING" id="930090.W6ZJZ5"/>
    <dbReference type="GeneID" id="19120572"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24325"/>
    <dbReference type="eggNOG" id="ENOG502SX0Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_597363_0_0_1"/>
    <dbReference type="OrthoDB" id="1077582at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="7">
        <location>
            <begin position="293"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="464" mass="54953" checksum="F959491C6385BD53" modified="2014-04-16" version="1">MPGRYVHPDWSLSIMPVAAVPLAITIAYGIYILAYPPATSLARKQSMLYLLVPAFFTFRYCDYISPDSNHVDTLARACIIWFAHMSYEVCILEFKPDVRPGPNEMKERIKQAYKVFFDRSHVQIVEQQQQHLQEHQKEYNSLSRAVYSINVEEKQSLIASEKKTDDALNTSEQKSQQHTPQARYQHGYSRWQFVLYHTLKTLRLYAQACAWEYYDYHVSPFRKDPDAYANKSQIPFFSRLPSSLHWREVYWRTEEAFSWNVPTKWMYESYHSVFAIIHVALGIDGPEEWGLGLFGNLSAAWSVRRYWRHYWHNFIYHSFSGHVKCVTRGWLGMPRNMFTRLVENTLVFFLSGLMHSAVRWQVAPWSDIWAITFMYTSQMVPLVIEGGVVCCWRKVRKSLGYGPDAKWVNYAEYAIGYFWAFAWQFYSVSTYWLVRDKWTEEKMARTYQKEMESWGLNETEVTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKM0</accession>
    <name>W6ZKM0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_81564</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682871.1">
        <property type="nucleotide sequence ID" value="XM_007684681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKM0"/>
    <dbReference type="STRING" id="930090.W6ZKM0"/>
    <dbReference type="GeneID" id="19125898"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81564"/>
    <dbReference type="eggNOG" id="KOG1620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042569_3_0_1"/>
    <dbReference type="OrthoDB" id="338650at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000824">
        <property type="term" value="F:inositol-1,4,5,6-tetrakisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008440">
        <property type="term" value="F:inositol-1,4,5-trisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF103">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE MULTIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC50538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="332" mass="36912" checksum="0929A723D550B3C1" modified="2014-04-16" version="1">MATKKYDASKLKAYDSAAAGHEGVLSDESGAVVVKPCTLSEITFYETLSDHPDLARHLPTFMGQLSLSTDQAAAVDSVESGTIKTADGSIERLHGKHLDTDLHIVLENITNGFKKPNVLDLKLGARLWDDNSKQEKRDRLDAVSKETTSGSLGFRIAGMRTYKGTDVPDVPDELKEYVEVDKDNGYWVYNKMYGRKFNAENVDEGFVSFIYPGAKSEAELDRAREVLAYFLGEVKDIQEVFESKESRMYSASILLVYEGDVEEYGNTKQKLRSAHPEDEDEEDENLPKLAEVKMIDFAHASWTPGQGPDENALQGMKSTATILKSLLDKAHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKV8</accession>
    <name>W6ZKV8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lactam utilization protein lamB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_88029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685351.1">
        <property type="nucleotide sequence ID" value="XM_007687161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKV8"/>
    <dbReference type="STRING" id="930090.W6ZKV8"/>
    <dbReference type="GeneID" id="19127184"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88029"/>
    <dbReference type="eggNOG" id="ENOG502RG2S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069535_1_0_1"/>
    <dbReference type="OrthoDB" id="5295431at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003814">
        <property type="entry name" value="PRK05406.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292:SF0">
        <property type="entry name" value="5-OXOPROLINASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBGL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="28019" checksum="745A163625F640EF" modified="2014-04-16" version="1">MPAIKHPVKINVDLGEGYGNFKCGPDEELIPLIDYANVACGFHAGDPLIMHNTILLCKSHSIAVGAHPGLPDIQGFGRREISMTPEELTALTRYQVGALQAFLDAENMPLNHVKPHGVLYGMMYRDETVCRAVYAGVPRGTTVFGLAGTNHERVAREMGLGFVAEVYGDVKYNRDGTLVIDRKKKPWHPDETRRHVRSQVENATVTAVTGEEVKLPVGDYEVSLCCHSDSPGAVEIVKAAREIVDEFNSKHFPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLP9</accession>
    <name>W6ZLP9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="6">PPIase</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_80760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682578.1">
        <property type="nucleotide sequence ID" value="XM_007684388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLP9"/>
    <dbReference type="STRING" id="930090.W6ZLP9"/>
    <dbReference type="GeneID" id="19125729"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80760"/>
    <dbReference type="eggNOG" id="KOG0879">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_4_3_1"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000035">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="181" mass="19760" checksum="E167EBD35E207DDC" modified="2014-04-16" version="1">MADTTEPNPVVFFDITLGGEKLGSIKMELFKNIVPKTAENFRQFCTGETKNNRGQPQGYKGCKFHRVIKGFMIQGGDFINGNGTGSRTIYGTEKFADENFTLQHDKPGLLSMANSGPNTNGCQFFIITAKNGTPHLNGKHVVFGNVVEGMDVVTKIENTRTLANPEGKPVQDIVIAQCGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMA6</accession>
    <name>W6ZMA6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_79670</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682179.1">
        <property type="nucleotide sequence ID" value="XM_007683989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMA6"/>
    <dbReference type="STRING" id="930090.W6ZMA6"/>
    <dbReference type="GeneID" id="19125521"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79670"/>
    <dbReference type="eggNOG" id="ENOG502QWTJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008241_2_0_1"/>
    <dbReference type="OrthoDB" id="103349at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF7">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="707"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="709"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC51215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="783" mass="88088" checksum="AB2B533C04FFD39D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMS0</accession>
    <name>W6ZMS0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10 11">Catalase-peroxidase</fullName>
            <shortName evidence="10">CP</shortName>
            <ecNumber evidence="10 11">1.11.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peroxidase/catalase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">katG</name>
        <name evidence="13" type="ORF">COCMIDRAFT_37312</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 10 11">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10 11">
            <text>H2O2 + AH2 = A + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30275"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="10">Binds 1 heme b (iron(II)-protoporphyrin IX) group per monomer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10">Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10 11">Belongs to the peroxidase family. Peroxidase/catalase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.21" evidence="10 11"/>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688579.1">
        <property type="nucleotide sequence ID" value="XM_007690389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMS0"/>
    <dbReference type="STRING" id="930090.W6ZMS0"/>
    <dbReference type="GeneID" id="19123225"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37312"/>
    <dbReference type="eggNOG" id="ENOG502QTDY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025424_2_0_1"/>
    <dbReference type="OrthoDB" id="407695at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070301">
        <property type="term" value="P:cellular response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08200">
        <property type="entry name" value="catalase_peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000002">
        <property type="entry name" value="Catalase-peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000004">
        <property type="entry name" value="Catalase-peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000002">
        <property type="entry name" value="Catalase-peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01961">
        <property type="entry name" value="Catal_peroxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000763">
        <property type="entry name" value="Catalase_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00198">
        <property type="entry name" value="cat_per_HPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011635">
        <property type="entry name" value="PRK15061.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555:SF0">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555">
        <property type="entry name" value="HYDROPEROXIDASE I, BIFUNCTIONAL CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00460">
        <property type="entry name" value="BPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10 11" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10 11" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="5 10 11" id="KW-0408">Iron</keyword>
    <keyword evidence="3 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 10 11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="12">
        <location>
            <begin position="127"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="cross-link" description="Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-93)" evidence="10">
        <location>
            <begin position="242"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00074141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC44876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="761" mass="84354" checksum="4FAE3C2E75E6403F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMT6</accession>
    <name>W6ZMT6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="12">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_79434</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Proline-directed serine/threonine-protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="12"/>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682274.1">
        <property type="nucleotide sequence ID" value="XM_007684084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMT6"/>
    <dbReference type="SMR" id="W6ZMT6"/>
    <dbReference type="STRING" id="930090.W6ZMT6"/>
    <dbReference type="GeneID" id="19125474"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79434"/>
    <dbReference type="eggNOG" id="KOG0660">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0075018">
        <property type="term" value="P:positive regulation of appressorium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07849">
        <property type="entry name" value="STKc_ERK1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000040">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000073">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC51410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="352" mass="40759" checksum="041D12BEC756C280" modified="2014-04-16" version="1">MPPAGSGSSRKISFNVSEQYDIQDVVGEGAYGVVCSALHKPSGQKVAIKKITPFDHSMFCLRTLREMKLLRYFNHENIISILDIQKPRNYETFTEVYLIQELMETDMHRVIRTQELSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNANCDLKVCDFGLARSAASTEDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEMLSGKPLFPGKDYHHQLTLILDVLGTPTMEDYYGIKSRRAREYIRSLPFKKKIPWKAMFPKTNDLALDLLERLLAFNPVKRISVEDALKHPYLEPYHDPDDEPGADPIPEEFFDFDKNKDNLTKEQLKLLIYQEIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP09</accession>
    <name>W6ZP09_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZP09"/>
    <dbReference type="GeneID" id="19126599"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85096"/>
    <dbReference type="eggNOG" id="ENOG502RJ9H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_518854_0_0_1"/>
    <dbReference type="OrthoDB" id="3781356at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="543" mass="60946" checksum="E895A7AFF178B164" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP75</accession>
    <name>W6ZP75_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="9">HMG-CoA reductase</shortName>
            <ecNumber evidence="9">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_95702</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-mevalonate + 2 NADP(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15989"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Endoplasmic reticulum membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="9"/>
    <dbReference type="EMBL" id="KI963985">
        <property type="protein sequence ID" value="EUC45411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688112.1">
        <property type="nucleotide sequence ID" value="XM_007689922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZP75"/>
    <dbReference type="STRING" id="930090.W6ZP75"/>
    <dbReference type="GeneID" id="19128711"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95702"/>
    <dbReference type="eggNOG" id="KOG2480">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001734_0_0_1"/>
    <dbReference type="OrthoDB" id="310654at2759"/>
    <dbReference type="UniPathway" id="UPA00058">
        <property type="reaction ID" value="UER00103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00643">
        <property type="entry name" value="HMG-CoA_reductase_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3270.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.420:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.770.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3270.10">
        <property type="entry name" value="HMGR, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025583">
        <property type="entry name" value="HMG-CoA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004554">
        <property type="entry name" value="HMG_CoA_Rdtase_eu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023282">
        <property type="entry name" value="HMG_CoA_Rdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00533">
        <property type="entry name" value="HMG_CoA_R_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13323">
        <property type="entry name" value="HPIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01192">
        <property type="entry name" value="HMG_COA_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="11">
        <location>
            <begin position="260"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="640"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC45411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1177" mass="126586" checksum="681182CA658157ED" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPK8</accession>
    <name>W6ZPK8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_95210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687945.1">
        <property type="nucleotide sequence ID" value="XM_007689755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPK8"/>
    <dbReference type="GeneID" id="19128606"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95210"/>
    <dbReference type="eggNOG" id="ENOG502SMK9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_25_4_1"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="44"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="326"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="326"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC45546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="370" mass="42296" checksum="0735BD6AFE50F6FF" modified="2014-04-16" version="1">MRSPPPEVLKTWPKPNYIDPVTRGPGLMIVELTLLPIAMIVVFLRLWVRISWLKKSWYDDYLMIVAMIFSIGTTIIVIMASQLYGWDRHAWDLKPHEMMVGRQASMAGQTLFVLASSTIKMSILVSYFRIAPEKSVFRKLVWATFALVFAAFVVFLVALWVQCIPISSYWKLNADHRDCIPEGPPLVVQSVLNVVTDFMIYALPIPTLFSLSLPWSQRIGLIVLFSVGGLIVVASSFRAYWIHYTLFRTYDATWEGYQIWVWTAIETNVGVICGCIPALKPLLFPHRARQQGSRYASGSQHSKKKEKITPVIDQVELDTRRLTENNDSQPELAISTQPAHHSTFSERPMSGDTDKSRFEIDIEQQKAYMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPT7</accession>
    <name>W6ZPT7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_84610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684018.1">
        <property type="nucleotide sequence ID" value="XM_007685828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPT7"/>
    <dbReference type="GeneID" id="19126495"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84610"/>
    <dbReference type="eggNOG" id="ENOG502R8N5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_728733_0_0_1"/>
    <dbReference type="OrthoDB" id="3694332at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="380" mass="42570" checksum="387C0B06AFCB4DDE" modified="2014-04-16" version="1">MQLAGTMMECYDNDEVSLRLHQALTGAGFANFPGNPPDDMEMEYEPLLNTLEELTLASPEEMQACEDTIMADMDEWVPINDEAQVGDEGKDLKDTDDISEEQYEHLRAKYLDPDCQPTDYVPCACIECIKLYEWDDPAGPSASFAPILYKPTFNFVQSIPKPVLTPRSHLLDPRCPSPSPPSPLPTNPAPPTKRTTVNPFPPSLYKTTTLLHCPSPTTPDPSTPMLPFYTQEYIRSLRLLKLRRRWSHLPLSDFTTELATLARSLANPANNLATWPPLAAWLAHYYATMQGVPRNRRHRVKMGLLKGLEEVCQVRVRENKAAVEELVEAKGERLVVGVWGMVRLGVDEDCEVRGSLGLGGLREFTDEVVGRMSGGWAWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRA1</accession>
    <name>W6ZRA1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 95 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_93425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687310.1">
        <property type="nucleotide sequence ID" value="XM_007689120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRA1"/>
    <dbReference type="GeneID" id="19128267"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93425"/>
    <dbReference type="eggNOG" id="ENOG502QQ9E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004617_2_2_1"/>
    <dbReference type="OrthoDB" id="2848340at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.50">
        <property type="entry name" value="putative glycoside hydrolase family protein from bacillus halodurans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049053">
        <property type="entry name" value="AFCA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016518">
        <property type="entry name" value="Alpha-L-fucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054363">
        <property type="entry name" value="GH95_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027414">
        <property type="entry name" value="GH95_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31084">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31084:SF0">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14498">
        <property type="entry name" value="Glyco_hyd_65N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21307">
        <property type="entry name" value="Glyco_hydro_95_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22124">
        <property type="entry name" value="Glyco_hydro_95_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007663">
        <property type="entry name" value="UCP007663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890176" evidence="1">
        <location>
            <begin position="20"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 95 N-terminal" evidence="2">
        <location>
            <begin position="25"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 95 catalytic" evidence="4">
        <location>
            <begin position="283"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha fucosidase A-like C-terminal" evidence="3">
        <location>
            <begin position="714"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="805" mass="89798" checksum="6D9DA4E98E6655AE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRB4</accession>
    <name>W6ZRB4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_36178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687300.1">
        <property type="nucleotide sequence ID" value="XM_007689110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRB4"/>
    <dbReference type="GeneID" id="19122965"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36178"/>
    <dbReference type="HOGENOM" id="CLU_1844889_0_0_1"/>
    <dbReference type="OrthoDB" id="3686429at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC46216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="138" mass="16071" checksum="6ECC4251DB0A6CC2" modified="2014-04-16" version="1">MRYHKPPHPSLLQTVPASDFKDLLTVALDLHACSLDLLNIIPLDNVDITLYLDRHPLATAKELLIRHDNLDREYGWVLASDRACVDRVLSKFCKAGRRPSEWFEEFMSELESVRRLLEEKVAQWEKVYSHKPSFLRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTB0</accession>
    <name>W6ZTB0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyltransferase family 62 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_80968</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682744.1">
        <property type="nucleotide sequence ID" value="XM_007684554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTB0"/>
    <dbReference type="STRING" id="930090.W6ZTB0"/>
    <dbReference type="GeneID" id="19125772"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80968"/>
    <dbReference type="eggNOG" id="ENOG502QVDT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017872_3_0_1"/>
    <dbReference type="OrthoDB" id="204164at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140497">
        <property type="term" value="C:mannan polymerase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000017">
        <property type="entry name" value="Mannan polymerase II complex ANP1 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF2">
        <property type="entry name" value="MANNAN POLYMERASE II COMPLEX ANP1 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="405"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="484" mass="55342" checksum="67223DC33CE15F3E" modified="2014-04-16" version="1">MLPSYSTSKGKMHRHAFSNGAYPSQGGGTFSIQPHKFQPRSQPALRRRRTLIQRLLLVGSLFFTALFFFFPNLRPNLGSGPLSLITSSDDSQLETVRYYDLNNVQGTARGWEREERILLCAPLRDASPHLPMFFSHLKNLTYPHNLIDLAFLVGDSKDNTISLLTEKLKELQADPDPKQQFGEISIMEKDFGQKVNQDVESRHGFAAQASRRKSMAQARNWLLSAALRPTHSWVYWRDVDVETAPFTILEDLMRHNKDVIVPNVWRPLPDWLGGEQPYDLNSWQESETALALADTLDEDAVIVEGYAEYATWRPHLAYLRDPYGDPDMEMEIDGVGGVSILAKAKVFRAGCHFPAFSFEKHAETEGFGKMAKRMKFSVVGLPHYTIWHLYEPSVDDIRHMEEMEKERKAKEAEEEAKKAKEAKIKESFDEKKGDWEKEKAAVQELIQKAKSEAKEGEQKDKQPEGKKKEEAKEEKPAEKKEDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZVF4</accession>
    <name>W6ZVF4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Mediator complex subunit 12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_89467</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SRB8-11 complex, which itself associates with the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 12 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685795.1">
        <property type="nucleotide sequence ID" value="XM_007687605.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZVF4"/>
    <dbReference type="GeneID" id="19127485"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89467"/>
    <dbReference type="eggNOG" id="KOG4522">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002034_1_0_1"/>
    <dbReference type="OrthoDB" id="20828at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057344">
        <property type="entry name" value="ARM_SRB8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019035">
        <property type="entry name" value="Mediator_Med12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46567">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46567:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25326">
        <property type="entry name" value="ARM_SRB8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09497">
        <property type="entry name" value="Med12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01281">
        <property type="entry name" value="Med12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med12" evidence="13">
        <location>
            <begin position="223"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1379"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1381"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1412"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1458"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1473"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1489"/>
            <end position="1506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC47741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1557" mass="172338" checksum="FD3437E5C20E3FC4" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0K6</accession>
    <name>W7A0K6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin-conjugating enzyme E2-16 kDa</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">E2 ubiquitin-conjugating enzyme 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin-protein ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_84309</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="11">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683883.1">
        <property type="nucleotide sequence ID" value="XM_007685693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0K6"/>
    <dbReference type="STRING" id="930090.W7A0K6"/>
    <dbReference type="GeneID" id="19126438"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84309"/>
    <dbReference type="eggNOG" id="KOG0417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_13_3_1"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032933">
        <property type="term" value="P:SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23792">
        <property type="entry name" value="UBCc_UBE2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000010">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2-16 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="12">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00074661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00077197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC49566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="147" mass="16512" checksum="3DF4E7DA9536D95C" modified="2014-04-16" version="1">MALKRINKELTDLGRDPPSSCSAGPIGDDLFHWQATIMGPGDSPYSGGVFFLAIHFPTDYPFKPPKVNFTTRIYHPNINSNGSICLDILRDQWSPALTISKVLLSICSMLTDPNPDDPLVPEIAHVYKTDRSRYESTAREWTRKYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3H5</accession>
    <name>W7A3H5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase</fullName>
            <ecNumber evidence="6">2.1.3.2</ecNumber>
            <ecNumber evidence="5">3.5.1.2</ecNumber>
            <ecNumber evidence="17">6.3.4.16</ecNumber>
            <ecNumber evidence="4">6.3.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">COCMIDRAFT_728</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="27 28">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="22">Multifunctional protein that encodes the first 2 enzymatic activities of the de novo pyrimidine pathway: carbamoylphosphate synthetase (CPSase; EC 6.3.5.5) and aspartate transcarbamylase (ATCase; EC 2.1.3.2). The CPSase-function is accomplished in 2 steps, by a glutamine-dependent amidotransferase activity (GATase) that binds and cleaves glutamine to produce ammonia, followed by an ammonium-dependent carbamoyl phosphate synthetase, which reacts with the ammonia, hydrogencarbonate and ATP to form carbamoyl phosphate. The endogenously produced carbamoyl phosphate is sequestered and channeled to the ATCase active site. ATCase then catalyzes the formation of carbamoyl-L-aspartate from L-aspartate and carbamoyl phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">In the C-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">In the N-terminal section; belongs to the CarA family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="6"/>
    <dbReference type="EC" id="3.5.1.2" evidence="5"/>
    <dbReference type="EC" id="6.3.4.16" evidence="17"/>
    <dbReference type="EC" id="6.3.5.5" evidence="4"/>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682801.1">
        <property type="nucleotide sequence ID" value="XM_007684611.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W7A3H5"/>
    <dbReference type="GeneID" id="19125238"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_728"/>
    <dbReference type="eggNOG" id="KOG0370">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000513_2_1_1"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005951">
        <property type="term" value="C:carbamoyl-phosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004087">
        <property type="term" value="F:carbamoyl-phosphate synthase (ammonia) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GATASE_TYPE_1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 24" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10 24" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-grasp" evidence="25">
        <location>
            <begin position="555"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="25">
        <location>
            <begin position="1090"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="26">
        <location>
            <begin position="1347"/>
            <end position="1497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00013008"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00043984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
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    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048859"/>
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    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
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    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00058513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00081752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="EUC50576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1829" mass="202138" checksum="43701CB587D8AF88" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3W4</accession>
    <name>W7A3W4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD/PDEase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_81086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007684527.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19125796"/>
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    <dbReference type="OrthoDB" id="2378324at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
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    </dbReference>
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        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35569">
        <property type="entry name" value="CYANAMIDE HYDRATASE DDI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35569:SF1">
        <property type="entry name" value="CYANAMIDE HYDRATASE DDI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="1">
        <location>
            <begin position="44"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="228" mass="25380" checksum="403A2E8DCF22E2CF" modified="2014-04-16" version="1">MCPPSDLASAAVRDVGGAPDHYPLEASLDTPISKAAYTHAASILHPSILNHSIRVFKYADEIAKHDSSKYFTDPHQRDLLFTACLLHDIGTTQEYNGPQRFEVEGADAAVKHLSHFGVSKEDAHCVWTAIACHTSPGIAERISELSRIVRIAVITDFRRDVTEWSTLEAMRERLEAQHERVGIEKVLGDAVVEQAKMDPRKAPKVSWPHAMYTAWLAEPDWDGVNKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W7A499</accession>
    <name>W7A499_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_80825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682588.1">
        <property type="nucleotide sequence ID" value="XM_007684398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A499"/>
    <dbReference type="GeneID" id="19125746"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80825"/>
    <dbReference type="eggNOG" id="ENOG502SIH3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036233_0_0_1"/>
    <dbReference type="OrthoDB" id="5413188at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="44436" checksum="018C665A51E9EF86" modified="2014-04-16" version="1">MHDHRPQRPGRQFASVEESHRPDQTMASSRPVASLARPSDESWIDIASGPSSTSLCSATDEIITTGLTVQHDSTLHRRQNRRSRGGGQFSIGTGHRVTAAGGNSSQEEYEESESESDRVMTSSNEALGLSPLRHDPSSRSPLSVASSETLSDREDDDDENATAVNYPRSTRREFQPRPNAFSRPNAQQAIRSHSGTLYTPRRAVRPTGQRQQSYPQHTPFNAVAPNYQPDHDEALRASLSTLLSAAAAVRGLPKPGQPRTAPPSSTRVDPTSLRMVPESVALGNISEESTSSPRSTSSSPSEKPKRKANPPMTAARSGSKDRRAVRKVRKSGPLIEEISPTLLTWVVSAGVVVLVSAIGFSAGYVAGKEAGHAEALGQVGAAGVDAGRCGKEAVSGMKGTGLGLRKLRWGSGAGIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YKR4</accession>
    <name>W6YKR4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_41768</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964252">
        <property type="protein sequence ID" value="EUC39787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693690.1">
        <property type="nucleotide sequence ID" value="XM_007695500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YKR4"/>
    <dbReference type="STRING" id="930090.W6YKR4"/>
    <dbReference type="GeneID" id="19124130"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41768"/>
    <dbReference type="eggNOG" id="ENOG502SG5D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102631_0_0_1"/>
    <dbReference type="OrthoDB" id="2257100at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF38">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="155"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="111"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="173"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC39787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="219" mass="24100" checksum="C67B9134A55648B2" modified="2014-04-16" version="1">MQYTSATMQFGSADWQLGPSYPASQDNNHLIDTSSLLASSSASTGHLIAPDASLYPTADFNLFPTGDSPYLGHDFQLFPQGHASLPTAGNTIDTLAMAQRMKLSNNMDTAAQMTRDGSQSDSSWTSHKDRSSSSPEHISSSKTCSTKSSPVVQEPSSRIEKRKANTLAARRYRQKRVDQMSTMEAELKEIKAERDELKVRNARLEGEVETLRALLRAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLV4</accession>
    <name>W6YLV4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_9902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964190">
        <property type="protein sequence ID" value="EUC40172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693310.1">
        <property type="nucleotide sequence ID" value="XM_007695120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLV4"/>
    <dbReference type="GeneID" id="19129380"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9902"/>
    <dbReference type="eggNOG" id="ENOG502SF0E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059948_0_0_1"/>
    <dbReference type="OrthoDB" id="5120991at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="388" mass="43714" checksum="F7028D75C8A0761D" modified="2014-04-16" version="1">MAVQTDAQVAQLCRSAFEAEHFSNFREAFDRHGDAITALNRLADDARFLDRERKRDAHKQAKFHGKRREVLQPILSGHKTRLDVVLPSSFSAQESLTKLINGLPCLSFDEMLLSRSLKPLHDKMRPTVPQGTAINSKQIVASLLASSKGNSALIPTEIQHIFPLNKDGTHSVSFYTPLLDKAQPDITFHVYVSCENVFTSGRWYYFKVKDSSERQTLYVLQGLKRPRYQVTKTSLSRATEFTTPCVETVVTPVRSTGSSHDGAIGRQLTHFTCSSLPVIDKPDRTKHVKWQPRRMAWGGRNFVWKQGKGMLEKELCEVKREWPQPGSKTGKMLDETFEPIVHAQTKVAVKKTLVVTFGYGCGIDFLFRELVLASLLTSHLVQAFGHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLY3</accession>
    <name>W6YLY3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_41420</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964185">
        <property type="protein sequence ID" value="EUC40217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693257.1">
        <property type="nucleotide sequence ID" value="XM_007695067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YLY3"/>
    <dbReference type="STRING" id="930090.W6YLY3"/>
    <dbReference type="GeneID" id="19124055"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41420"/>
    <dbReference type="eggNOG" id="KOG4157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024893_2_0_1"/>
    <dbReference type="OrthoDB" id="2537459at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041738">
        <property type="entry name" value="GG_III-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861">
        <property type="entry name" value="GLYCOPROTEIN 38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861:SF4">
        <property type="entry name" value="SH3 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G13610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889222" description="WSC domain-containing protein" evidence="3">
        <location>
            <begin position="28"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="29"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="388" mass="41246" checksum="89DF6BD7A7C9D79D" modified="2014-04-16" version="1">MHNRFTSTLFGFAAFSTLLLSIQPAGASDWTYPYCSSLNTGEQDTAYTWPYQSNGNCTNHCKEEGGSWAFAVIKYTDCWCSNYVPGDTASLSDCLQDCPGFPDEKCGSKDKGLYIYVQMDGQPSGTKGGSQPSSTAAAPSKQSQQPQSQPQSQQPTYAPPPAQVVTSIVTQKPETVFSTVTAELDSTSSSSSTDTKKPSSTQAPSQTQEPVTVPTLVTESGNVVTRTVVITPSAPAPATNDSKDSPNVGAIAGGVAGGIIGLLAIIGIVFFVLWKRRRQQREGQEGGGGIQRNVSTMSRAGLLGGRAEKSPTPLTTTFGSQRSRSNEESITPMTPSTRRLSQPILVDSRLNPAAVLTFHGANLSRESLGSIDDSRDYGRQLNVRNPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNR7</accession>
    <name>W6YNR7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zinc finger CHCC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_30110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964123">
        <property type="protein sequence ID" value="EUC41032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692433.1">
        <property type="nucleotide sequence ID" value="XM_007694243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNR7"/>
    <dbReference type="STRING" id="930090.W6YNR7"/>
    <dbReference type="GeneID" id="19121615"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30110"/>
    <dbReference type="eggNOG" id="KOG3456">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083053_0_0_1"/>
    <dbReference type="OrthoDB" id="307899at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.40:FF:000003">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="2">
        <location>
            <begin position="133"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="212" mass="23402" checksum="E2582EBE647BAD93" modified="2014-04-16" version="1">MLPITLRALRSRSAATASRPFARYVSTATTSNQVPANDPVKRDAKPNVSATNEMATSSEGSFDQVLQESVQDAEELRTTQAPNYKGIWSRSQNPRAVAMSGPRFEQTIIADQPRPYAAIELIHQQPVRWTHDRVVSCDGGGGPLGHPRIFINTDKPQICWCTYCGLPFAHEKHRAVLEATPEHELSYPLGPKGNAAEVNETQKVTDEPLSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YNZ2</accession>
    <name>W6YNZ2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_107076</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="KI964120">
        <property type="protein sequence ID" value="EUC41102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692389.1">
        <property type="nucleotide sequence ID" value="XM_007694199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YNZ2"/>
    <dbReference type="STRING" id="930090.W6YNZ2"/>
    <dbReference type="GeneID" id="19118976"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107076"/>
    <dbReference type="eggNOG" id="ENOG502SATK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015488_0_0_1"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF10">
        <property type="entry name" value="GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001100">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00656">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <sequence length="382" mass="41491" checksum="DDFD55C6B7EC31B7" modified="2014-04-16" version="1">MVQVTQFVLATAALAGAATAFPKPEPRNTTVNPWIGKDRYVVERYGKKLDQTIASFLAKNDPLNAARTRTVAKKTSTFVWVTSRAGLSQIPEAIEQARRQRKGRKRMIVGLVLYNLPDRDCSAGESAGELSSAKDGLNIYKHEFVDKYAQLVSEAKDLDFAIVLEPDSLGNAVTNQGVPFCANATPIYEQGIAYAIAKLQFPNVSLYMDAAHGGWLGWADNLKPTAQIFARVVEAAKKINPAAKIRGYSTNVSNYNPFNAKVRENYTEWSPSWDESHYATSLGAAMAAEGMPTNFIIDQGRVALPGARKEWGEWCNVSPSGFGLRPGPAPNNTNVDSIVWIKPGGESDGACGLAGAPVAGAWFDDYVQMLVKNADPPLEPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YP56</accession>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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    </reference>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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        <source>
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    <sequence length="80" mass="7667" checksum="5AE09BA934717E98" modified="2014-04-16" version="1">MPLLTAIITLAIASPALAGPAAYGVCQAGCSAVVMACYSAAGFTWGATLGASAPASIIACNTAFGTCQAACAAVLLTPML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPF5</accession>
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        <recommendedName>
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    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Bushley K.E."/>
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
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                <person name="Han J."/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
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        <property type="entry name" value="PMF1/Nnf1"/>
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    </dbReference>
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        <property type="entry name" value="POLYAMINE-MODULATED FACTOR 1"/>
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    <dbReference type="Pfam" id="PF03188">
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    <dbReference type="PROSITE" id="PS50939">
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    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
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            <end position="93"/>
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    <feature type="transmembrane region" description="Helical" evidence="17">
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    <feature type="transmembrane region" description="Helical" evidence="17">
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        <location>
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            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="18">
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            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="469"/>
            <end position="786"/>
        </location>
    </feature>
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        </location>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="521"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
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    <feature type="compositionally biased region" description="Low complexity" evidence="16">
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    <feature type="compositionally biased region" description="Low complexity" evidence="16">
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    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="740"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC41247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="786" mass="85984" checksum="25D0D5DC72BA1480" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPY3</accession>
    <name>W6YPY3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Luciferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_10268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964284">
        <property type="protein sequence ID" value="EUC39665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_10268"/>
    <dbReference type="eggNOG" id="ENOG502S0WG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="9987011at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048273">
        <property type="entry name" value="Luciferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040841">
        <property type="entry name" value="Luciferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17648">
        <property type="entry name" value="Luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Luciferase" evidence="2">
        <location>
            <begin position="177"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="304" mass="33666" checksum="AF7634710C275E89" modified="2014-04-16" version="1">MQDLAPDLNASFSSIAPQPATMPTETYMHGLAVTLGLLLFPIITAFYVHKDYCAFLSLGPGGTPATPLGYLKIKLLSLICLRDPRRPIPIPPHYRPQRGYFFEDALPHRTGHKPEIRGIAPQRQQTQVSTKEIYGKLVLKIKELASDPRNRLTERTSCFEKHSTGLFTSIPITRTCGGEICHAHPSDGSMHLTLHPADANLIMAHGWGERHPLARGGWCRKFVPREFMLVYAPRDDEEVEIVTKIVAASIWWVSGINVSGDTEGPRRKSADVAAIGREMQGDQCWACRVNTCGGNKVEQMASDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ01</accession>
    <name>W6YQ01_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_111133</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964317">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ01"/>
    <dbReference type="STRING" id="930090.W6YQ01"/>
    <dbReference type="GeneID" id="19119717"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_111133"/>
    <dbReference type="eggNOG" id="KOG1001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_2_7_1"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF52">
        <property type="entry name" value="SINGLE-STRANDED DNA-DEPENDENT ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="67"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="474"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC39593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="652" mass="74087" checksum="703AF583490B5CD4" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQ82</accession>
    <name>W6YQ82_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_31148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964255">
        <property type="protein sequence ID" value="EUC39775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693702.1">
        <property type="nucleotide sequence ID" value="XM_007695512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQ82"/>
    <dbReference type="GeneID" id="19121807"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31148"/>
    <dbReference type="HOGENOM" id="CLU_1539876_0_0_1"/>
    <dbReference type="OrthoDB" id="3691291at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889305" evidence="2">
        <location>
            <begin position="23"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC39775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="182" mass="17729" checksum="28FF1BB65A30B55C" modified="2014-04-16" version="1">MLASTSISASTVLLLLASVAVAQDASTTASPSASPTSTSEGAFTIQTSVPAQDPWSCFEECFMEPCPPSPCSSTPNASLGTPVPLPRPISESIASIITDPSLSTVTGVMTIPAGETPISTGASVTSTGTSSSQARSSSSQTGSTRSPTSSGAPTATGNAVALNANAHLAPLAAAAAGAFALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR25</accession>
    <name>W6YR25_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_41626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964216">
        <property type="protein sequence ID" value="EUC39958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693518.1">
        <property type="nucleotide sequence ID" value="XM_007695328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR25"/>
    <dbReference type="STRING" id="930090.W6YR25"/>
    <dbReference type="GeneID" id="19124104"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41626"/>
    <dbReference type="HOGENOM" id="CLU_068940_0_0_1"/>
    <dbReference type="OrthoDB" id="5958943at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050778">
        <property type="entry name" value="Cueball_EGF_LRP_Nidogen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000033">
        <property type="entry name" value="LDLR_classB_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46513">
        <property type="entry name" value="VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00135">
        <property type="entry name" value="LY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013334328" description="SMP-30/Gluconolactonase/LRE-like region domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="39229" checksum="8C0D0619D202A5F2" modified="2014-04-16" version="1">MLLPSVFTLFQLSTALPRLQPRVSQYLVVLDTGVGHRSTPIPRWPTSLRRINTDGSNAANLTQFGVVVSDPNTLEQPILAYALTYSPSTSSLFSATGRGVVRTNIEGGNLEYILNKESDPSSQVVSITAAEQSQKLYYGDSNTGLIYSSNYNGSNVAVFRNVSQGLTFLSEDYSYANTHAGGIVVDEARGWLYWSSVSDGSIRRVLLSGEGQEQVIVTGLDKPGQLRIAGTSLYFAERGSWSSSPTAIKYLGRMIDELPASPTSPNLAVPTRTLISSTQSSLFTEIDYTGEKQTLGIESFVVYRNGVEQIVYFAVNSAGRTSFGKIVETVWRGSGDSRGPVFKVLNAETKDVGIPVGLEHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRR9</accession>
    <name>W6YRR9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_30852</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964191">
        <property type="protein sequence ID" value="EUC40163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693319.1">
        <property type="nucleotide sequence ID" value="XM_007695129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRR9"/>
    <dbReference type="GeneID" id="19121757"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30852"/>
    <dbReference type="eggNOG" id="ENOG502S0S9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051542_0_1_1"/>
    <dbReference type="OrthoDB" id="2094832at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051654">
        <property type="entry name" value="Meroterpenoid_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897:SF1">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="31613" checksum="DC834D49DDD261BD" modified="2014-04-16" version="1">MCPESSHASWYMEEPETIKPAIREVFEKHSNIRPELVAEHIKQVRDRAYQITHYPCIGGYYFLDLKAREAPCYPEIKRRVLNGEKLLDVGCCLGQEIHRMVTDGMPAENLYGCELKMELVNLGYEMFLDKEYLASKFIVANIFETPSELDQLDGQISIVHAQYFFHLFTWDDQLRLANRLVKLSKPSCEFLIFGGHMGANQETEPYHPDTGKFFIHSDESWRRLWDQVGSETKTSWEVETARKPADPNLLWLCGPDAYFMTFVVRRVQASCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS90</accession>
    <name>W6YS90_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like modifier HUB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_108708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964161">
        <property type="protein sequence ID" value="EUC40490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692996.1">
        <property type="nucleotide sequence ID" value="XM_007694806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS90"/>
    <dbReference type="STRING" id="930090.W6YS90"/>
    <dbReference type="GeneID" id="19119295"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108708"/>
    <dbReference type="eggNOG" id="KOG3493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156193_2_1_1"/>
    <dbReference type="OrthoDB" id="3881at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039732">
        <property type="entry name" value="Hub1/Ubl5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13042">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="77" mass="8499" checksum="F2FF4E29E85E998E" modified="2014-04-16" version="1">MILVTINDRLGTKTQVPCLPSDPIKLLKAMVAAKIGRPVHEIMLKRQGERPFHDNLTCADYAISNGVQIDLELNTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YS98</accession>
    <name>W6YS98_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 32 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_108927</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964169">
        <property type="protein sequence ID" value="EUC40388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693086.1">
        <property type="nucleotide sequence ID" value="XM_007694896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YS98"/>
    <dbReference type="STRING" id="930090.W6YS98"/>
    <dbReference type="GeneID" id="19119334"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108927"/>
    <dbReference type="eggNOG" id="KOG0228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013784_3_0_1"/>
    <dbReference type="OrthoDB" id="202537at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18621">
        <property type="entry name" value="GH32_XdINV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 32 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="5">
        <location>
            <begin position="47"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="6">
        <location>
            <begin position="463"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC40388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="624" mass="69184" checksum="EF99EB3C920956DD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSB8</accession>
    <name>W6YSB8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_103822</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964065">
        <property type="protein sequence ID" value="EUC42332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691166.1">
        <property type="nucleotide sequence ID" value="XM_007692976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSB8"/>
    <dbReference type="STRING" id="930090.W6YSB8"/>
    <dbReference type="GeneID" id="19118382"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103822"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF229">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="57937" checksum="5091B3C85131BAC3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSG2</accession>
    <name>W6YSG2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_108487</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA1 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964155">
        <property type="protein sequence ID" value="EUC40560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692917.1">
        <property type="nucleotide sequence ID" value="XM_007694727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSG2"/>
    <dbReference type="STRING" id="930090.W6YSG2"/>
    <dbReference type="GeneID" id="19119255"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108487"/>
    <dbReference type="eggNOG" id="ENOG502S786">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132216_1_0_1"/>
    <dbReference type="OrthoDB" id="1920692at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC40560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="86" mass="9866" checksum="1F11AE770148C93D" modified="2014-04-16" version="1">MGVPFEALLPYAIMTGFFAFSAVSVGKLQEIQNGGKRKRRGIDAWDRVMMERDRRLTGFMRGQTDKPVAPAGFELNNPWRCEQRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSR6</accession>
    <name>W6YSR6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AMP deaminase</fullName>
            <ecNumber evidence="4">3.5.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Myoadenylate deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_108458</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="4"/>
    <dbReference type="EMBL" id="KI964154">
        <property type="protein sequence ID" value="EUC40573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692905.1">
        <property type="nucleotide sequence ID" value="XM_007694715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSR6"/>
    <dbReference type="STRING" id="930090.W6YSR6"/>
    <dbReference type="GeneID" id="19119250"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108458"/>
    <dbReference type="eggNOG" id="KOG1096">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003782_0_0_1"/>
    <dbReference type="OrthoDB" id="1723809at2759"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01319">
        <property type="entry name" value="AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.800.20:FF:000001">
        <property type="entry name" value="AMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000214">
        <property type="entry name" value="AMP deaminase Amd1, putative (AFU_orthologue AFUA_8G02860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000300">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="147"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="288"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="898"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="946"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="900"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="952"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00078830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC40573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1081" mass="121281" checksum="90BFEC2AD3707B99" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTI1</accession>
    <name>W6YTI1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cobalamin-independent methionine synthase MetE C-terminal/archaeal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_102633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964050">
        <property type="protein sequence ID" value="EUC42762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690736.1">
        <property type="nucleotide sequence ID" value="XM_007692546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTI1"/>
    <dbReference type="STRING" id="930090.W6YTI1"/>
    <dbReference type="GeneID" id="19118121"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102633"/>
    <dbReference type="eggNOG" id="ENOG502QQV2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058877_0_0_1"/>
    <dbReference type="OrthoDB" id="7772923at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844:SF2">
        <property type="entry name" value="SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="1">
        <location>
            <begin position="184"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="406" mass="46196" checksum="BD4E0098C892A6EC" modified="2014-04-16" version="1">MTSLKRSPPFRAEHVGSLLRPQELVQKRYDVASGKAQPDELVPLEDKSVAEVVKFQQDCGLKVVSSGEYTRHMFWGTFFETLHGMKELQLGVLKGYNKDMFRAYAPDVKSFMEAKEVPNHVTVCVDKIRHPGKSSNQREVDLMKSLLPESEWKNIKITLISPSWYHFRYMNGSAYPKEVYANDEEYFADVAKAYQEELKILHSQGIRNIQIDDPNLAYFCSDDMLAGWKADKTNSKTADEMFDSYVKFYNKCFERPADMHLGIHLCRGNYVGSRHFSEGAYDLIAKKLFQDLDVDTYYLEYDTPRAGGFEPLEHLPKGKNVVLGVITSKFPKLEDKDEMIARVNQAADWIAKGTGQSHEDALKQCCVSPQCGFASHAEGNALGYEDMRKKLQLVRSIADAVWPGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU47</accession>
    <name>W6YU47_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Quinate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_102027</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964043">
        <property type="protein sequence ID" value="EUC42982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690513.1">
        <property type="nucleotide sequence ID" value="XM_007692323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU47"/>
    <dbReference type="GeneID" id="19117997"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_102027"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="508119at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF34">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="24"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC42982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="528" mass="59334" checksum="741FFA6C16DB9A4A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU54</accession>
    <name>W6YU54_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_107166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964122">
        <property type="protein sequence ID" value="EUC41058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692420.1">
        <property type="nucleotide sequence ID" value="XM_007694230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU54"/>
    <dbReference type="STRING" id="930090.W6YU54"/>
    <dbReference type="GeneID" id="19118994"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107166"/>
    <dbReference type="eggNOG" id="KOG1889">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003016_7_4_1"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072517">
        <property type="term" value="C:host cell viral assembly compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052629">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004438">
        <property type="term" value="F:phosphatidylinositol-3-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="621"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="2">
        <location>
            <begin position="117"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="703" mass="78775" checksum="8E4572B65EB35C41" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUC6</accession>
    <name>W6YUC6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mannosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_7469</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 22 family. PIGB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="KI964041">
        <property type="protein sequence ID" value="EUC43067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690418.1">
        <property type="nucleotide sequence ID" value="XM_007692228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUC6"/>
    <dbReference type="STRING" id="930090.W6YUC6"/>
    <dbReference type="GeneID" id="19125296"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7469"/>
    <dbReference type="eggNOG" id="KOG1771">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012353_1_0_1"/>
    <dbReference type="OrthoDB" id="416834at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the peptidase S10 family.</text>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
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    </dbReference>
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        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
    </feature>
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            <end position="628"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC43312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="628" mass="68889" checksum="809C58BCB5B3A40C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV87</accession>
    <name>W6YV87_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_29783</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964102">
        <property type="protein sequence ID" value="EUC41455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV87"/>
    <dbReference type="GeneID" id="19121568"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29783"/>
    <dbReference type="HOGENOM" id="CLU_940051_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="296" mass="32842" checksum="21F97E732C25B834" modified="2014-04-16" version="1">MSQHLLSAIKSARRHPGRGVESVRRLPARGRVLGGSAQRSAETQMQTELRVELSTQSDIPQAAGCSLHPSTSPPAQIHTSCCWAIPSNTIKLWPRRKLRARVQRIWHTWTRLLTARPCAAYYIKATRVISAAALTYLHAYIHTYIRGVRGSMSVCPSVRQSGETYIHRLHTYIYIYTTAGVAHVTRRVTPSQRACRSRQQQKKCSGRAAIWRQGSSHGGPSDQQPHAPDARQGRTAPRAGCRAGHNARQGHGPWRARGQSAREGERARHVEGEGEGEAAEAVVVCQIRRRDATEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVD4</accession>
    <name>W6YVD4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_105965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964099">
        <property type="protein sequence ID" value="EUC41505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YVD4"/>
    <dbReference type="STRING" id="930090.W6YVD4"/>
    <dbReference type="GeneID" id="19118778"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105965"/>
    <dbReference type="eggNOG" id="KOG0406">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="202840at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF8">
        <property type="entry name" value="S-TRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="97"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27072" checksum="DA36D15102836AE4" modified="2014-04-16" version="1">MAHVNGNAPKITLYTNHRCPYAHRAHIVLKELGLPYEEVIIDLDTPREPWYLEINPRGLVPAIKFNGEIVTESATVSTFLADAYPSHLFPATGSPEAALTRARINFFVDTWSTKAGSHWYKILTQDSEEEKAKLSQEFIETVSKELEPLLKDAKPFFGGSEKLTLAEALTAPFIIRIYAFSRRGVLPKSIAADLDALPNFSKWAAAVTKQESVTYVFDEDSIISSTVKRLEKMKEKNQAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXD2</accession>
    <name>W6YXD2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_39725</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964070">
        <property type="protein sequence ID" value="EUC42180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691293.1">
        <property type="nucleotide sequence ID" value="XM_007693103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXD2"/>
    <dbReference type="GeneID" id="19123740"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39725"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_0_1"/>
    <dbReference type="OrthoDB" id="2585655at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF29">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="490"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="75"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="566" mass="61978" checksum="ED6DD5814F24CB19" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXE2</accession>
    <name>W6YXE2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enolase</fullName>
            <ecNumber evidence="3">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_104101</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Mg(2+) is required for catalysis and for stabilizing the dimer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="3"/>
    <dbReference type="EMBL" id="KI964069">
        <property type="protein sequence ID" value="EUC42203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXE2"/>
    <dbReference type="STRING" id="930090.W6YXE2"/>
    <dbReference type="GeneID" id="19118442"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104101"/>
    <dbReference type="eggNOG" id="KOG2670">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031223_0_0_1"/>
    <dbReference type="OrthoDB" id="1739814at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
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    </dbReference>
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        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
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        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="15">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="14">
        <location>
            <begin position="143"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="374"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="398"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00031125"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00032132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC42203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="438" mass="47236" checksum="71EADBF141429804" modified="2014-04-16" version="1">MAITKIHARSVYDSRGNPTVEVDIVTETGLHRAIVPSGASTGSHEACELRDGDKSKWGGKGVTKAVANVNDTIAPALIKEKLDVKDQSAVDAFLNKLDGTKNKTNLGANAILGVSMAIAKAAAAEKGVPLYAHISDLAGTKKPYVLPVPFQNVLNGGSHAGGRLAFQEFMIVPSEAPTFSEAMRQGAEVYQKLKSLAKKTYGQSAGNVGDEGGVAPDIQTPEEALDLITKAIEEAGYTGKIKIAMDVASSEFYKADEKKYDLDFKNPDSDKSKWLTYEQLAELYKSLAEKYPIVSIEDPFAEDDWEAWSYFFKTSDFQIVGDDLTVTNPEFIKKAIELKSCNALLLKVNQIGTITEAIQAAKDAFGAGWGVMVSHRSGETEDVTIADIVVGLRAGQIKTGAPARSERLAKLNQILRIEEELGDNAIYAGNNFRTAINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXM8</accession>
    <name>W6YXM8_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_103910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007693001.1"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="OTU_dom"/>
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    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
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    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF7">
        <property type="entry name" value="OTU DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="21"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="332" mass="37149" checksum="4B556458C22D8FAC" modified="2014-04-16" version="1">MATRRHRANSPEFPILDANALYASSIRGDGNCLFNALSDQLYGHQDMHEVLRATTIEHMRDCSDFYRQYMAVNTVRRNPKRKTAAANAATKRLDTTYYTEEQLQQQFEHHVEKMGQPGEWADNMEVSAFASALNVNVRLWQADYTYLFSPRMTSASNADPAADDKRQTLHIAYHTWEHYSSVRNIAGPHTGIPNVNVVPKAMSKKRPSPSVDGDDDDQRQRSRKRRSPLPLFDSDSTPEGTDSSSDESHGFVASQQSTLQTPPPEPPRPVKLTIKLRGLRTCDASSTDSSREPTPAPKTILHTDTRPVPAEASPLKTPAVSKPLTPCYDFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXR7</accession>
    <name>W6YXR7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Retinol dehydrogenase 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_103696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964064">
        <property type="protein sequence ID" value="EUC42348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691133.1">
        <property type="nucleotide sequence ID" value="XM_007692943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXR7"/>
    <dbReference type="GeneID" id="19118360"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103696"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF33">
        <property type="entry name" value="OXIDOREDUCTASE BLI-4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="37305" checksum="BC45978CEA9FA2F0" modified="2014-04-16" version="1">MQTIKNTIAENFGKTISGAHSLAPADQQFSLEEVPDLSGKVAVVTGGSEGIGYGCTHTLLSKNISKLFIISMSKDIASDAISAIASELGQDKASRVEWLQCDLSDWSAVSRTSFEITQKTDRLDILINNAGRGIMTYQLASNGVDLHMAINHMGHAVLTSHLLPLLKSTAATGTKVRIAQLASNAHQNAPSDVSFSSLEELNQDLGPNGQYGRSKLAAILYVRYLARHLASSHPNVLVNATHPGVVETRQSVEHIHEAYPLAGYGVSVGLAPFKKTQFEGAVSTMFAATKTEKSGQYVCPPAIPEPGSEMSRDEELGERLMKLTEEVVREKTMGESKGKGCPFRFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYA8</accession>
    <name>W6YYA8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Extracellular mutant protein 11 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_27299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964006">
        <property type="protein sequence ID" value="EUC44322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689123.1">
        <property type="nucleotide sequence ID" value="XM_007690933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYA8"/>
    <dbReference type="GeneID" id="19121097"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27299"/>
    <dbReference type="eggNOG" id="ENOG502STPQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_559051_0_0_1"/>
    <dbReference type="OrthoDB" id="5346740at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070860">
        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001164">
        <property type="term" value="F:RNA polymerase I core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029178">
        <property type="entry name" value="Ecm11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053029">
        <property type="entry name" value="RNA_pol_I-specific_init_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244:SF3">
        <property type="entry name" value="EXTRACELLULAR MUTANT PROTEIN 11 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15463">
        <property type="entry name" value="ECM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Extracellular mutant protein 11 C-terminal" evidence="2">
        <location>
            <begin position="397"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="544" mass="61371" checksum="7162F6A622BCD060" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYI8</accession>
    <name>W6YYI8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ML-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_9525</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964150">
        <property type="protein sequence ID" value="EUC40624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692851.1">
        <property type="nucleotide sequence ID" value="XM_007694661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYI8"/>
    <dbReference type="STRING" id="930090.W6YYI8"/>
    <dbReference type="GeneID" id="19128617"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9525"/>
    <dbReference type="eggNOG" id="ENOG502QSVZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010226_1_0_1"/>
    <dbReference type="OrthoDB" id="5212126at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF2">
        <property type="entry name" value="FLAVIN CARRIER PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886938" description="ML-like domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="562"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="10">
        <location>
            <begin position="24"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="624"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="701"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="725" mass="79508" checksum="0488785ECCBE6280" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYN4</accession>
    <name>W6YYN4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Btz domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_37663</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CASC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688981.1">
        <property type="nucleotide sequence ID" value="XM_007690791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYN4"/>
    <dbReference type="STRING" id="930090.W6YYN4"/>
    <dbReference type="GeneID" id="19123297"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37663"/>
    <dbReference type="eggNOG" id="ENOG502QUZZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018142_1_0_1"/>
    <dbReference type="OrthoDB" id="5413466at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018545">
        <property type="entry name" value="Btz_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044796">
        <property type="entry name" value="MLN51_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46837">
        <property type="entry name" value="PROTEIN MLN51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46837:SF5">
        <property type="entry name" value="PROTEIN MLN51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09405">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01044">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Btz" evidence="14">
        <location>
            <begin position="122"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="112"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="434"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC44477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="691" mass="75039" checksum="4FF2EB6E1A96CCFB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0A5</accession>
    <name>W6Z0A5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cystathionine gamma-synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_26620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963990">
        <property type="protein sequence ID" value="EUC45117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688333.1">
        <property type="nucleotide sequence ID" value="XM_007690143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0A5"/>
    <dbReference type="STRING" id="930090.W6Z0A5"/>
    <dbReference type="GeneID" id="19120965"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26620"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_3_0_1"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000072">
        <property type="entry name" value="Putative cystathionine beta-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000066">
        <property type="entry name" value="Putative cystathionine beta-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF35">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE (AFU_ORTHOLOGUE AFUA_7G01590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="416"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC45117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="48078" checksum="0DC86561594E7DF3" modified="2014-04-16" version="1">MPSYHASTYGIHADDRINALTDVAPPIHTSTTFRYPRNPDKLQPVPDEGEFVDLQTPLVYSRLASASTNRLETILAPLMYPDATESELDGSNGLANHVVSYTSGLSAFHALLVNVVPKVVAISGGYHGCHGVIELHKKMHGVKTVDLHADESAWDAVGLGKGDLVHLETPLNPTGEAFEIAKYAKRAHARGALLSVDATFAPPSLQDAFKWGADFVMHSGTKYIGGHSDMLCGILATSAGPEGLKRAKILRAERIFLGAVLGNLESWLGVRSLRTLDLRVQRQSSNADNLVGWLNDSLNGKGEDTEAVKKVVSEVKHASLQTSDMSWLKQQMPNGFGPVFSIYMKEAKQARTLPSHLRLFHHATSLGGVESLIEWRRMSDTEVDERLLRVSVGVENWEDLKNDFLNAFKALASGEATQQTNDSQKVQVGQDGAQMPEAGAGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0G1</accession>
    <name>W6Z0G1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_96054</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688261.1">
        <property type="nucleotide sequence ID" value="XM_007690071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0G1"/>
    <dbReference type="GeneID" id="19128777"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96054"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF78">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="22"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="551" mass="61100" checksum="CAEC932A06ED8B55" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0M6</accession>
    <name>W6Z0M6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_28040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964027">
        <property type="protein sequence ID" value="EUC43515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689974.1">
        <property type="nucleotide sequence ID" value="XM_007691784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0M6"/>
    <dbReference type="STRING" id="930090.W6Z0M6"/>
    <dbReference type="GeneID" id="19121230"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28040"/>
    <dbReference type="eggNOG" id="KOG2551">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051938_2_0_1"/>
    <dbReference type="OrthoDB" id="2094269at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="313" mass="34224" checksum="08BA5D9D57F25DFF" modified="2014-04-16" version="1">MAAAAPPPNRPIKILMLHGYTQSGPLFQAKTGALRKTLNKAFPKGIELVYPTGPIRLTPTDFSLITGAVTDRTSAPDADEELDAWAWWRKRSTSDGSYVFDGLDEGFAHIASILKEQGPFDGVIGFSQGAAATAMVASLLEPKRKQAFDAQHAAGTGIPFPASFEGNIHPPLKFAVSYSGFAAIPPPPPPPQQQQQDGSTPTSQYMAFYEPEIETPILHFLGTQDVVIEEARSLVLVQRCKRKEDKYVVYHPGGHFLPSTQKASVNALVGFIREVLWEQEGAKEENEDNLEDIMGHFDAKKPAVAEQEAKFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1N8</accession>
    <name>W6Z1N8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_99671</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CENP-W/WIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964017">
        <property type="protein sequence ID" value="EUC43870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689616.1">
        <property type="nucleotide sequence ID" value="XM_007691426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1N8"/>
    <dbReference type="STRING" id="930090.W6Z1N8"/>
    <dbReference type="GeneID" id="19129512"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99671"/>
    <dbReference type="eggNOG" id="ENOG502SEGJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159428_1_1_1"/>
    <dbReference type="OrthoDB" id="2543597at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13732">
        <property type="entry name" value="HFD_CENP-W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000075">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052484">
        <property type="entry name" value="CENP-W/WIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="8">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC43870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="76" mass="8731" checksum="FB5C3FC1F825BBC5" modified="2014-04-16" version="1">MAPTLYPRGTVKKIVKAHSNRPLSKNVDILIYLNYVLFMQELINEASIKSKQRGERGISARNVKRVSEDVLRKYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z366</accession>
    <name>W6Z366_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_104421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691394.1">
        <property type="nucleotide sequence ID" value="XM_007693204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z366"/>
    <dbReference type="STRING" id="930090.W6Z366"/>
    <dbReference type="GeneID" id="19118498"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104421"/>
    <dbReference type="eggNOG" id="ENOG502RYMZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_13_0_1"/>
    <dbReference type="OrthoDB" id="5819582at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="60"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="477" mass="53862" checksum="38DA27A1D8FBD6FD" modified="2014-04-16" version="1">MLNLAETTLGETEKGLPSPSILGVSARYRSIHRRILRNLLPSFLLHNSTAARDEIRPTDFLDGMRGYAAFIVYCCHFFMPTHPQATRGFKGYNSDEDHWFTQLPIIRLIYSGHVSVSLFFVISGFSISLKPLKLIRNGSYSAFLDTMVSAIFRRPCRLYLPCLATLAITLIVACCGAFDFSYALTKNWPFLSKPLRIPIAHHSLSKQFADWAGQVWTWSDPLARRTRHPPYGVQLWTIPIELSCSFISFLALISFAKVRPAVRMSITTVIGVYFLFQNHPEATLFLAGTTLAELYLIRQELAVSAPSRSTESRKQKIQSSLLFGFGLFVASYPAAEGEKALFSAPLHYIASTLFGPSIRCPNLFITMGTVILVYVVSRSPFLQSMFATHVAKYLGKISFALYCVHQAMINSFGYRSMLFLWSFTGNDTVYRYELGLFLSWVIQTIVTIWAADVFWRFVDVPSVGISKWLEELCLVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3N1</accession>
    <name>W6Z3N1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_6174</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688923.1">
        <property type="nucleotide sequence ID" value="XM_007690733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3N1"/>
    <dbReference type="STRING" id="930090.W6Z3N1"/>
    <dbReference type="GeneID" id="19124871"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6174"/>
    <dbReference type="eggNOG" id="KOG2024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002346_0_0_1"/>
    <dbReference type="OrthoDB" id="408320at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005990">
        <property type="term" value="P:lactose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000018">
        <property type="entry name" value="Beta-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF2">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="domain" description="Beta galactosidase small chain/" evidence="7">
        <location>
            <begin position="751"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1036" mass="115931" checksum="716DFB3375B63EF9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3S7</accession>
    <name>W6Z3S7_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_25609</name>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="EUC46402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="183" mass="19845" checksum="DB48439CA7032A19" modified="2014-04-16" version="1">MGAHGGRVGCKLLRCQGSSAMWEKRFQIRWALQGRRVTTHTLDAPPAAGSRTRLGDCVSIRMKAPPPHTGVRSDFNKRIPSNGGMRCWGARRAQHSVYSGAPEGSLYSWGRACERAVAGLLGGPRRMPYASRHVAGGNAEAGYGHEARGSNAGTRRRLARMQKTSLPIYDSARDDWLWAGSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3Z8</accession>
    <name>W6Z3Z8_COCMI</name>
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    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_6245</name>
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        <lineage>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    <dbReference type="eggNOG" id="ENOG502S5MV">
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    </dbReference>
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    <dbReference type="OrthoDB" id="429427at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071008">
        <property type="term" value="C:U2-type post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:spliceosomal complex disassembly"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Ntr2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <end position="317"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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            <end position="420"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="428" mass="47268" checksum="0048BD26D30D8CD9" modified="2014-04-16" version="1">MKRSSSTRVARKIGSYDDDESADSTNSSQNEVQKPTVVKRPALGKAKKRSSLRMSFGAGDEANNGEESSDSAVVTPKKANLSRIALEKSAQLRARSPLVSESAKPTEYSKDYIAELRNSTPSTPRDLKISAEEEEEIRALDIAAKFGPVASLETTSSAIPTEAEIREKKARRRRLAHEENAYDGEDAAWASDDQGEDEFRQHRDKISLRPKDKWGETRLVHDDEDIAEGFDDYVEDGKIALGRKSEKEAQRRRRAEMAELINDAEGSSGDDGSGDSDEDRNFAFAAAQARAGRYGQKVDEDDDGTRTPPRITPLPDLDDILQGLTIDIEARKQRKALLLQKMQDLKDDKVRIEERKKYLQEQLQKTGEEYEKLRQESGLPALPTNTLEAGGGSRMITERGLDSLGTTPLGGTPLAGTPLANRSSEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4Q7</accession>
    <name>W6Z4Q7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_97457</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963998">
        <property type="protein sequence ID" value="EUC44713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4Q7"/>
    <dbReference type="GeneID" id="19129065"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97457"/>
    <dbReference type="eggNOG" id="ENOG502SHPH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043969_0_0_1"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF157">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="26"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="382" mass="42828" checksum="BC706BFCF725AFC5" modified="2014-04-16" version="1">MYLRPGFVVVIVGGVLTTISTIVVGLRYYCRYFLVGSLSASDHLMLVSLVVAWGTFIINYYQDVTSSGYRPAYLRRPDKRPEIEGYVLGVLISWWAYRFVYVIGLGFIKLSILFFYRSIAANVTFRRTVYGMMGFVVMYTFSATIAAIFQCQNPASAWSTTNYFAQFDPTLKREPAVCWDPVPLWVFSSACNLLTDILLLLMPLPTLLSLRIPMGKRLALIGIFSVGLMAIVASSVRMWVMYMWAESPYNSARYGADLLLWGQVETNSGIISASVPFLRLLFRNKERKPQKIYATPPEAQPPTPPKNDEYSPGQVPGVEMWPLANEKGLDRGESVGFITIHERSTIARESNWGPFVTIPESLSSDGKDSPYLAPALSPHKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z627</accession>
    <name>W6Z627_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lon protease homolog 2, peroxisomal</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_95500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9 12">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="KI963984">
        <property type="protein sequence ID" value="EUC45430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688042.1">
        <property type="nucleotide sequence ID" value="XM_007689852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z627"/>
    <dbReference type="STRING" id="930090.W6Z627"/>
    <dbReference type="GeneID" id="19128670"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95500"/>
    <dbReference type="eggNOG" id="KOG2004">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004109_4_0_1"/>
    <dbReference type="OrthoDB" id="2411602at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5270:FF:000002">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000091">
        <property type="entry name" value="Lon protease homolog 2, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000039">
        <property type="entry name" value="Lon protease homolog 2, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03121">
        <property type="entry name" value="lonp2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027501">
        <property type="entry name" value="Lonp2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="ATP DEPENDENT LON PROTEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="15">
        <location>
            <begin position="14"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="14">
        <location>
            <begin position="727"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Microbody targeting signal" evidence="8">
        <location>
            <begin position="926"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 10 12">
        <location>
            <position position="820"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 10 12">
        <location>
            <position position="863"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <begin position="484"/>
            <end position="491"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EUC45430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="928" mass="101329" checksum="12F808B9CB2B735F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6H2</accession>
    <name>W6Z6H2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_90596</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686202.1">
        <property type="nucleotide sequence ID" value="XM_007688012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6H2"/>
    <dbReference type="GeneID" id="19127719"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90596"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_0_1"/>
    <dbReference type="OrthoDB" id="2585655at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:001500">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF20">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_1"/>
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    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="443"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="66"/>
            <end position="506"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="526" mass="56890" checksum="71A837A45BA6FBBB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z705</accession>
    <name>W6Z705_COCMI</name>
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        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_94716</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
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    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
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            <end position="68"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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            <end position="390"/>
        </location>
    </feature>
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        <location>
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            <end position="423"/>
        </location>
    </feature>
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        <location>
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            <end position="450"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC45755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="535" mass="58672" checksum="77F413DB1DCE774A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7F1</accession>
    <name>W6Z7F1_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_26222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963980">
        <property type="protein sequence ID" value="EUC45673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7F1"/>
    <dbReference type="GeneID" id="19120900"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26222"/>
    <dbReference type="HOGENOM" id="CLU_1834809_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="140" mass="14839" checksum="315E4550FA74DD34" modified="2014-04-16" version="1">MPHRYCLAQPLLSPPTARLTVAARLHSTLLLHPITSSSNVCPSSPSTTCASAPTPRARLRLRLRLRPRPSSRLNGPWPSILSIRSPSAACQPPRRALLCASLLRLSAGIAAKAESWVTFCNHGGGAIASRHVPDTSPIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8A9</accession>
    <name>W6Z8A9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_4707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963970">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="entry name" value="Clavaminate synthase-like"/>
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    </dbReference>
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            <dbReference type="EMBL" id="EUC46200.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="45062" checksum="BCCFCE6257107D57" modified="2014-04-16" version="1">MNDYSTPNGVNHGRQELGIQPRLYSINNPPSLEGFKKLTTESSSIDYPLASTIKSHVPIYHLPDYSSSSPEQLAALQDEWYHILLSGPGVFVTKNLYKDTSLINDVNKVYSSIIEEEKQASSRRGDHFAGAGANDRIWNSLSKHRLLDAASFVRYYSNPWLPLISEAWLGPYHRLTAQVNIVKPGAKAQISHRDYHIGFQDSESCARFPRVVQVTSQFLTLQGAVAHSDMPVESGPTRLLPFSQKFEQGYMAYRIPEFQDFFLENHVSLPLEKGDGLFFNPALFHAAGQNDSADIMRSANLLQISSAFGKPMESIDTYPLVESTWDALSEMYVKNGLSDEVKAFVSVVAEGYPFPTNLDKRVPQAAGMAPTSEQDLILKCLKDHVPKEDVLSQLQKMKEDSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8C0</accession>
    <name>W6Z8C0_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">COCMIDRAFT_94035</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EUC46038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689303.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z8C0"/>
    <dbReference type="GeneID" id="19128373"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94035"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003731_0_0_1"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007234">
        <property type="term" value="P:osmosensory signaling via phosphorelay pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ethylene receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000289">
        <property type="entry name" value="Osmosensing histidine protein kinase SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="12 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="18">
        <location>
            <begin position="553"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="19">
        <location>
            <begin position="988"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="419"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="721"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="879"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1148"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="728"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="897"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="920"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="14">
        <location>
            <position position="1043"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EUC46038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1179" mass="129396" checksum="FFC6B185CE0B5A4B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z978</accession>
    <name>W6Z978_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_23973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            <strain evidence="3 4">ATCC 44560</strain>
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</entry>
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        <name evidence="2" type="ORF">COCMIDRAFT_35701</name>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
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                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </evidence>
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            <dbReference type="Google" id="ProtNLM"/>
        </source>
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</entry>
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        <lineage>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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            <end position="481"/>
        </location>
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        <location>
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            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="EMBL" id="EUC48552.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
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        </alternativeName>
    </protein>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
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                <person name="Bushley K.E."/>
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                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
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                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007686805.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6ZA11"/>
    <dbReference type="GeneID" id="19127009"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87217"/>
    <dbReference type="eggNOG" id="KOG1706">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032784_4_2_1"/>
    <dbReference type="OrthoDB" id="1688907at2759"/>
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        <property type="reaction ID" value="UER00113"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000053">
        <property type="term" value="P:argininosuccinate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="ASS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000019">
        <property type="entry name" value="Argininosuccinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1260.10:FF:000003">
        <property type="entry name" value="Argininosuccinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="entry name" value="Argininosuccinate synthetase, chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048268">
        <property type="entry name" value="Arginosuc_syn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048267">
        <property type="entry name" value="Arginosuc_syn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001770">
        <property type="entry name" value="PRK00509.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587:SF2">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20979">
        <property type="entry name" value="Arginosuc_syn_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="Argininosuccinate synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginosuccinate synthase-like N-terminal" evidence="12">
        <location>
            <begin position="5"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Arginosuccinate synthase C-terminal" evidence="13">
        <location>
            <begin position="178"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC48577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="415" mass="46839" checksum="94CD5BAF74BB58C4" modified="2014-04-16" version="1">MSKGRVCLAYSGGLDTSTILKWLIEEGYEVVCFLANVGQDEPWDEVEKKALKIGALKMVILDLQKEFVEELCFRAVQCNASYEGRYLLGTSLARPVIARAQIRVAQQEGCGFVSHGCTGKGNDQVRFELAFYTLQPSIKVIAPWRLPEFCDRFKGRQDLLDYAEKHGIPVTSTKAKPWSMDANLAHCSYEAGILEDPDVSPPDDMWTMTDSPLNAPNEPTDITVYFEKGIPVKVVTPEKTYTDSVELFVALNKLGYTHGIGRIDIVENRFIGLKSRGCYDSPAMTILRLAHLDLEGLVMDAQVRNLRDQFVSHNWSYQLYNGMYFSPEREFIENSLLFSQRRVNGEVRMKLYKGNAYVLGRSSKTEKLYSEEEASMDTLDNFSPMDTTGFIAIQSIRLKKYGLQKAEEGANMSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA99</accession>
    <name>W6ZA99_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_35498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963959">
        <property type="protein sequence ID" value="EUC46910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686557.1">
        <property type="nucleotide sequence ID" value="XM_007688367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA99"/>
    <dbReference type="GeneID" id="19122796"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_35498"/>
    <dbReference type="HOGENOM" id="CLU_1053770_0_0_1"/>
    <dbReference type="OrthoDB" id="3695651at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="261" mass="29036" checksum="B57312ED3571B185" modified="2014-04-16" version="1">MNARFMARMARYLDRGVEDLGGGGGEEERGEKGGMVGKRKRDCGDEGEETEEGEKEEKEKEKGKEVPLRKLTVKLKLVRCGVERGDGDGDGTSSSSCTFSQQQQQQQQRPGPSGQPKPSKQVQTTTSKLPALKTKPKSLAKTNADSPPKMLTRQSTRNLAPLSTMPTGPPKQKPARTPYFPHLHVTNEPPIPWHPIPLPCPYLPDDYEGPRAAWKRLFPNEAEFGEYGGRPTGWMAKMTWKAEEGWVERGEGDVYVERFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB93</accession>
    <name>W6ZB93_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Nnf1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_91166</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963957">
        <property type="protein sequence ID" value="EUC47098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686444.1">
        <property type="nucleotide sequence ID" value="XM_007688254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB93"/>
    <dbReference type="STRING" id="930090.W6ZB93"/>
    <dbReference type="GeneID" id="19127827"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91166"/>
    <dbReference type="eggNOG" id="ENOG502S9JT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064565_1_0_1"/>
    <dbReference type="OrthoDB" id="18453at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007128">
        <property type="entry name" value="PMF1/Nnf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15459">
        <property type="entry name" value="POLYAMINE-MODULATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15459:SF3">
        <property type="entry name" value="POLYAMINE-MODULATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03980">
        <property type="entry name" value="Nnf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24486" checksum="8A893DBB7A99E2EC" modified="2014-04-16" version="1">MMPAATNSNSRSPSPTPARPIAETPGPRAQGLINVFNQASKATLDKCSAKNFASCFPTAAQYSPEVLDNLRGQIVDQLDRTWKSNFEDIMERRNVVKLLNSLDQCIEDARLRKKRAEESANGGPVETPVPPHTLSPAEIHLAHLMPFLEKQATTMNTKLAETQQANTELLSTVTAQRAEIESLVRGLENVIKDIEASAQTMAQDDVQDLSKETRDLEMAMRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBE7</accession>
    <name>W6ZBE7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_3698</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat cdt2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686138.1">
        <property type="nucleotide sequence ID" value="XM_007687948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBE7"/>
    <dbReference type="STRING" id="930090.W6ZBE7"/>
    <dbReference type="GeneID" id="19123156"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3698"/>
    <dbReference type="eggNOG" id="KOG0321">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018451_0_0_1"/>
    <dbReference type="OrthoDB" id="2096344at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051865">
        <property type="entry name" value="WD-repeat_CDT2_adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852:SF0">
        <property type="entry name" value="DENTICLELESS PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852">
        <property type="entry name" value="LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="258"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="300"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="613"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="679" mass="74380" checksum="3284B572A819E4A8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBH1</accession>
    <name>W6ZBH1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_90600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686189.1">
        <property type="nucleotide sequence ID" value="XM_007687999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZBH1"/>
    <dbReference type="STRING" id="930090.W6ZBH1"/>
    <dbReference type="GeneID" id="19127721"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90600"/>
    <dbReference type="eggNOG" id="KOG0908">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_14_0_1"/>
    <dbReference type="OrthoDB" id="19690at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="112"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="155" mass="17135" checksum="42B029CEDC68119B" modified="2014-04-16" version="1">MPTEISAPLHFRTLLNAHTYLIADFYATWCPPCKQIAPVYNQFSNAHSVPGKFAFVKVNVDEQREIAGQYGVTAMPTFMLFKDGKKIEEVRGADVRGLKAMVEKAGGDVKAMEEKAKKTEEAKKATENGKGEEEEKTVSGSYGMTGGNHWKMSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBL7</accession>
    <name>W6ZBL7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_30048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964118">
        <property type="protein sequence ID" value="EUC41141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692343.1">
        <property type="nucleotide sequence ID" value="XM_007694153.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZBL7"/>
    <dbReference type="GeneID" id="19121608"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_30048"/>
    <dbReference type="eggNOG" id="KOG1840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_15_1"/>
    <dbReference type="OrthoDB" id="3694819at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="16"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="28923" checksum="24F80749DDBF1B5E" modified="2014-04-16" version="1">MESRKRVLGSKHPDTLVSVNNLGSVLESQGKYEEAEAIYQRAIEVREKVLRHKHPNTLTSVSNLGSVLERQGKYEEAEVMHRRDLEGSKKVLGRERPNTLTSVSNLGVVLERQGKYEEAEVMHRRDLEGSKKVLGREHPNTLTSVNNLGVVLERQGKYEEAEVMHRRXEHPNTLTSVNNLGVVLERQGKYEEAEVMHRRALEGNLLICTAERVTGTAWSSESITLIPEHVANTIAKCFYYMSSLGWQVLDREIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCC2</accession>
    <name>W6ZCC2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_1704</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683936.1">
        <property type="nucleotide sequence ID" value="XM_007685746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCC2"/>
    <dbReference type="STRING" id="930090.W6ZCC2"/>
    <dbReference type="GeneID" id="19119931"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1704"/>
    <dbReference type="eggNOG" id="KOG2360">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005316_7_4_1"/>
    <dbReference type="OrthoDB" id="435282at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1170:FF:000006">
        <property type="entry name" value="NOL1/NOP2/Sun domain family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049561">
        <property type="entry name" value="NSUN5_7_fdxn-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048889">
        <property type="entry name" value="NSUN5_RCM1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF4">
        <property type="entry name" value="28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21148">
        <property type="entry name" value="NSUN5_fdxn-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21153">
        <property type="entry name" value="NSUN5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="7">
        <location>
            <begin position="138"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="340"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="530"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="558"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="568" mass="62671" checksum="4571D1FEC37DD4E8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCX8</accession>
    <name>W6ZCX8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">60S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_5484</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963987">
        <property type="protein sequence ID" value="EUC45279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688169.1">
        <property type="nucleotide sequence ID" value="XM_007689979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCX8"/>
    <dbReference type="STRING" id="930090.W6ZCX8"/>
    <dbReference type="GeneID" id="19124632"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5484"/>
    <dbReference type="eggNOG" id="KOG0397">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061015_3_0_1"/>
    <dbReference type="OrthoDB" id="1734943at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_uL5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057266">
        <property type="entry name" value="Ribosomal_uL5_euk/arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003258">
        <property type="entry name" value="PRK04219.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="6">
        <location>
            <begin position="14"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="7">
        <location>
            <begin position="71"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC45279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="20546" checksum="C9592FFDF77740AD" modified="2014-04-16" version="1">MDFSITMSDSKASNPMRELRIQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELRKRNFSESGNFGFGISEHIDLGIKYDPSIGIYGMDFYVCMTRPGERVAKRRRCKSKIGPSHRVNQAETIKWYKNRFEGIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDA7</accession>
    <name>W6ZDA7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_22570</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="3">Belongs to the WD repeat AIP1 family.</text>
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        <property type="protein sequence ID" value="EUC49792.1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_22570"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_015246_1_0_1"/>
    <dbReference type="OrthoDB" id="2306at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0005884">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:actin filament depolymerization"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:actin filament severing"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="197"/>
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    </feature>
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        <location>
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    <feature type="repeat" description="WD" evidence="4">
        <location>
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    </feature>
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        <location>
            <begin position="541"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00038366"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC49792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="575" mass="60973" checksum="6FD0D52E174D38CA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEI6</accession>
    <name>W6ZEI6_COCMI</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">COCMIDRAFT_87322</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963941">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_87322"/>
    <dbReference type="eggNOG" id="ENOG502T5M9">
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    <dbReference type="OrthoDB" id="3672650at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="347" mass="40366" checksum="3EDB7528CF90EB43" modified="2014-04-16" version="1">MATLHQRMSNKLSMISNRSSDGLYKHRQSLLFRELEILLELNPSTFSSPLLALPREIRDQIFSYVLPDTSKDRPELHTCLWSAEMSNGEPWRHDIFGYGPSVPNALRLRPELLLINKQIREELLQNYFRRSKITLHAELRNTRANNEYFEFSQHILRLPMLKHTTHVRFYLEWNYTTLRNGSRDRMLKDQMRMTYNLLASIDKILQPLPNIETIELSVLFFWKYRSGKMYSLSMQDLFDLEGVFKRCAELRWLGLLGENDLPGKVKHTTSTYLSPSSAIPQTSSAGVGYKMSTERKGTEQSGGMEICISRDLSDAMEERRKSTVDFFGNYEIGEPLPLPSYRHGAMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEJ5</accession>
    <name>W6ZEJ5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Actin-related protein 2/3 complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_39929</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Cytoskeleton</location>
            <location evidence="7">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the WD repeat ARPC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964079">
        <property type="protein sequence ID" value="EUC41946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691523.1">
        <property type="nucleotide sequence ID" value="XM_007693333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEJ5"/>
    <dbReference type="STRING" id="930090.W6ZEJ5"/>
    <dbReference type="GeneID" id="19123776"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39929"/>
    <dbReference type="eggNOG" id="KOG1523">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034396_1_0_1"/>
    <dbReference type="OrthoDB" id="406844at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000601">
        <property type="term" value="P:positive regulation of Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000220">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038093">
        <property type="entry name" value="ARP2/3_su1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC41946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="364" mass="39831" checksum="8B993E5453511810" modified="2014-04-16" version="1">MPGPEVHHLFNSPIADHSFSADRQTLAVARENNVDVFQRSGNGYKPKDELTGHDKTVTGVDIAPKSGKIVTCSQDRNAYVWEPSPQGWKPTLVLLRINRAATCVRWAPSETKFAVGSGARLIPVCYFEEEDNWWVSKHLKKPIRSTVTCVSWHPNSVLLAAGSTDGHARVLSSFVKGVDERPEPSAWGERLPFNTVCGEYLNSTAGWIHSVAFSPSGNALAFAAHDSTLTVVYPSGPEQAPRAIVSVSTQVLPFMSLIWSSEDEIIAAGYNCEAFRLKGNESGWQLTGSLETKSRPGLADQREESALNMFRQMDLKGKSGTDDTKLKTVHQNTINTIRSFEESGSGVTKISSTGVDGRIVIWTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZEK0</accession>
    <name>W6ZEK0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_39935</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="KI964079">
        <property type="protein sequence ID" value="EUC41951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691524.1">
        <property type="nucleotide sequence ID" value="XM_007693334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZEK0"/>
    <dbReference type="STRING" id="930090.W6ZEK0"/>
    <dbReference type="GeneID" id="19123778"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39935"/>
    <dbReference type="eggNOG" id="KOG3355">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070631_2_1_1"/>
    <dbReference type="OrthoDB" id="59470at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060904">
        <property type="term" value="P:regulation of protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.310:FF:000002">
        <property type="entry name" value="Sulfhydryl oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF1">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ERV2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="65"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="172" mass="18966" checksum="D9B3BBEDDCBB72D6" modified="2014-04-16" version="1">MFRVAGLRARFAVLAILVMALCSFLLLGPYKVAPGHLTFATPGRDLGHTSQSLLTGHAIAPKLGNATAKAELGRAAWKVLHTTFARFPEKPTEEEKEALRSYVHLFQRLYPCGECAEHFGQVLAKYPPQVSSRTAAAMWGCYVHNIVNKRLKKPEFNCEDIGDAYDCGCAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF44</accession>
    <name>W6ZF44_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GTPase-activating protein GYP5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_32265</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the GYP5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683026.1">
        <property type="nucleotide sequence ID" value="XM_007684836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZF44"/>
    <dbReference type="STRING" id="930090.W6ZF44"/>
    <dbReference type="GeneID" id="19122060"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32265"/>
    <dbReference type="eggNOG" id="KOG1102">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008177_0_0_1"/>
    <dbReference type="OrthoDB" id="295078at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000044">
        <property type="entry name" value="GTPase-activating protein GYP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="3" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="12">
        <location>
            <begin position="392"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="426"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="758"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="431"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="449"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC50442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="901" mass="98403" checksum="3266F36048D20968" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFL0</accession>
    <name>W6ZFL0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_8129</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="KI964067">
        <property type="protein sequence ID" value="EUC42271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691201.1">
        <property type="nucleotide sequence ID" value="XM_007693011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFL0"/>
    <dbReference type="STRING" id="930090.W6ZFL0"/>
    <dbReference type="GeneID" id="19125842"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8129"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000012">
        <property type="entry name" value="Betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="484" mass="52620" checksum="F21C3C0E8CA52A7E" modified="2014-04-16" version="1">MAASIETRLFINNEFRNARSGESFTVRQSYDDSIVAENVQIAGEQDVNDAVDAAHAAFKHWRRTPAPERAKYMLKLADLIEENLDWLAELETAAMGAPISATRWIASSMPTWWRYYAGWTDKLGGESVEDLDGSYRMVRYEPLGVCAGIASWNATLFYLCWKIAPAVAAGNTFIFKSSEKAPLGALRFAELVRRAGFPPGVINLITGFGQTGGLLASHQKIRKISFTGSTLTGRKIQIAAANSNLKRVTLELGGKSAAIVFDDADIDEALTHMSQTFLLNCGQVCAATSRLLVQDTIAESFVAELKTRFQGFANALGDPSDPNTFLGPIADRMQRERVTSFIDAARSENLNILAGGQSQGPQNQFIQPTIILDPPSSSTLYRDEIFGPVLVIKTFKSEAEAIDMANDSAYGLGAALFTKDVPRALRLSSDLECGFVGINMPIQPSAYTPFGGAKESGYGREGGRLGLMAYLEPKTVAIAMKPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGQ6</accession>
    <name>W6ZGQ6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963934">
        <property type="protein sequence ID" value="EUC49210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684361.1">
        <property type="nucleotide sequence ID" value="XM_007686171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGQ6"/>
    <dbReference type="GeneID" id="19126641"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85310"/>
    <dbReference type="HOGENOM" id="CLU_733588_0_0_1"/>
    <dbReference type="OrthoDB" id="3695199at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="369" mass="41578" checksum="DD5C8DAB78126676" modified="2014-04-16" version="1">MAPEQGDEEQERKHYEAMNMNGKLRPMAMRIGFRNVNRWNQRQLVTIFLEYDRINPIRARNIPKDHKTTPAEIEAQHALVDRLIKEKKLQVPVPKRKRENGTTTGNNKRVKISSGDDDHISPSDSGKSNDKRVPRHVSGTKGVSKTGSRSDGVQKKSKQTEKPAATKPAPTKPAPTKPAPTKPRSRQASTLKPRQKKTNMDVGNPQDAESQNPSAPAVDPPFVTPGANPGDDDDSSESDDSDSGDDNGDDVHDDEDIEERDEDFEAEEISKAPSKNQGAPKTTGTSKGKGKDTSEVKAKPLGLHLGVRKIDRYTSLDWDPLNESIPNSRLTWYEQEQRFRAQQEKTRKEAQEEEPKKEWDWKKQLRRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHE9</accession>
    <name>W6ZHE9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_33193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684073.1">
        <property type="nucleotide sequence ID" value="XM_007685883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHE9"/>
    <dbReference type="GeneID" id="19122265"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33193"/>
    <dbReference type="HOGENOM" id="CLU_1266770_0_0_1"/>
    <dbReference type="OrthoDB" id="3691660at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="198" mass="22741" checksum="D0278B57273CF242" modified="2014-04-16" version="1">MTDHTNDQNNKHNTPQWGRYTRFMELEGSLFPDNEGDFASSFMNPRRPRDQSDQPAPFGNRVWTGEAFVYAPPPRPEEQMDFDSYQNPSLRQSGMTEVPGSAGILPGSPHVGGPSYLGNPQGSGSARQQDKDKFQFVGWNDEAKRMLYRWKRILKKGPSFFLHQFPGETEASLRDAWDKYGEEGKRLYEEWEAAQEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHU4</accession>
    <name>W6ZHU4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_79548</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682268.1">
        <property type="nucleotide sequence ID" value="XM_007684078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHU4"/>
    <dbReference type="GeneID" id="19125498"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79548"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_8_7_1"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005628">
        <property type="term" value="C:prospore membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005275">
        <property type="term" value="F:amine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030476">
        <property type="term" value="P:ascospore wall assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF21">
        <property type="entry name" value="DITYROSINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="66"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC51402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="502" mass="54413" checksum="56ADE1F2E47CD34F" modified="2014-04-16" version="1">MRSPIEFEKSHHYDQCRDSIESDRSSSRHSVDEEAQQSFADDVPLAPCPPPAQPYSAFSLNRRRFILGVVTAAGFFGPLCGAVYLPSLRLFQKIFNASEAAINGTVSIYMVVFAVAPLFGAAASDVGGRKTVYMVGLGSFLIANSLLATLPAYIWLLYILRIFQAFGSCIVFSVGAGTVADITEPASRASALAWFLMGPQLGPILGPLIGGQFATESRWRWVFAFLSITSFPVYLAIVFCMPETLRSLVGNGASVAKQPWISMPKLWTKPCTDTNVPKVPRPSFRKFMRLLKYPPHLIVCFNGAFQFAGLYGMYISFPTIWQEGYNWTTAEVGYAFLCPGIAMFLASIVVGRLSDYMRKKAIANSPDGKVAPERRIAIQIPGFLCAAAGKLMFGWFTLNHLHPALALCGAALAAVGVSIVFVTSTSFQTECDPTQTASLVALGGFLRNVAAAICAAIMGGILDGMGWGWAFTGLGIMDLLCIPGIVLILVRGAKWREELKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHW6</accession>
    <name>W6ZHW6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbohydrate-binding module family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_91230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC47009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686514.1">
        <property type="nucleotide sequence ID" value="XM_007688324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHW6"/>
    <dbReference type="GeneID" id="19127838"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91230"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011025_0_0_1"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF2">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G17620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890032" evidence="4">
        <location>
            <begin position="24"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="5">
        <location>
            <begin position="821"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="785"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="788"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC47009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="859" mass="90406" checksum="E6B266988C1BF447" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHX9</accession>
    <name>W6ZHX9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_1641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHX9"/>
    <dbReference type="GeneID" id="19119914"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1641"/>
    <dbReference type="eggNOG" id="ENOG502SIDW">
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    <dbReference type="OrthoDB" id="5169850at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32437" checksum="4334AC6E8C914870" modified="2014-04-16" version="1">MSELTNIRVPTPSNPSNLAPRYEIRKLKPVHLPWATAILAHSHGFHSNVWQKIWPDRDLGRWVVENSLNFEYLVRHQIDSGLSFGVFDTEYVFKTDAARATGGALLWDADEQATQSVEKTQGRAAEAKRLLDQMDFPLVSIILSYDGFKPLDPEKMKPLLAAWPEFPILYGVLEKRDQRDPASWKATAPRQVLMRNATSTRGDYEGRGIMGAAARWLQREAALMGFRGIQIEAMADRVIRVWTEGVQKPFKGTVVSEFECQTLEVDGEKPFGAARQRVVKAWVDLTA</sequence>
</entry>
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    <name>W6ZIG6_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_7208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="entry name" value="Sialate-O-sulfotransferase"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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            <begin position="140"/>
            <end position="230"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="408" mass="42617" checksum="9B1B742795F36358" modified="2014-04-16" version="1">MRHNSFAPLLLLAPATIIAATLRQRELSPATQLSDSWAYSGCYVDSIAVRALNSASQGDGTSMSAQTCTAFCGARGYPVAGLEYGSECWCGTALPSQVATDPATCNMPCSGDSPQVCGGPDRLTVYSRPAFSRTKPSPTGWQSLGCYTDNVSARTLSDPRAAGDQMSVELCASACAGSKYFGVEYAGECFCGDNILNGGTSASDGCNMPCRGDTSEFCGGSNRLNLYQAVQSQPEPVCAPTIQTGGQIFNGGFELGSTWTRNPSTTGISKEVSGLAYEGCYSELISPINPASALRSVAIVSNAGVTPGSVHTFSFYLGRRSSSAGYGALVNMKLTTPAGVVYWGLTFQACAGAQCNLVGTGGTVWKKYQTTIYFNYAQSLPLTITTSWSGATKLDGTDDVFIDGITIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIH0</accession>
    <name>W6ZIH0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_24937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963956">
        <property type="protein sequence ID" value="EUC47169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIH0"/>
    <dbReference type="GeneID" id="19120665"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24937"/>
    <dbReference type="HOGENOM" id="CLU_2037620_0_0_1"/>
    <dbReference type="OrthoDB" id="10349376at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="82"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="121" mass="13744" checksum="86E0549D8AF597CB" modified="2014-04-16" version="1">MQDCRLAQKSSGHRVGPTHISSVQRILVMKQRQQKHVTYVSCCETCRHAFTIGPAFMRVQFPKFTVRLGDSATMWSSLSRRAMRRSASKPPYDVFQKRKPQARGQVSLPVSSTPFYSAEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIS0</accession>
    <name>W6ZIS0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rrn9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_7050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964027">
        <property type="protein sequence ID" value="EUC43486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689961.1">
        <property type="nucleotide sequence ID" value="XM_007691771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIS0"/>
    <dbReference type="STRING" id="930090.W6ZIS0"/>
    <dbReference type="GeneID" id="19125163"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7050"/>
    <dbReference type="eggNOG" id="KOG3234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017870_2_0_1"/>
    <dbReference type="OrthoDB" id="5412288at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019622">
        <property type="entry name" value="Rrn9_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10680">
        <property type="entry name" value="RRN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rrn9" evidence="2">
        <location>
            <begin position="109"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
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</entry>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Xue C."/>
                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Han J."/>
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                <person name="Wang R."/>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683189.1">
        <property type="nucleotide sequence ID" value="XM_007684999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJT4"/>
    <dbReference type="GeneID" id="19126020"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82263"/>
    <dbReference type="eggNOG" id="ENOG502QPYR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026803_0_0_1"/>
    <dbReference type="OrthoDB" id="425936at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027372">
        <property type="entry name" value="Phytase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37957">
        <property type="entry name" value="BLR7070 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37957:SF1">
        <property type="entry name" value="PHYTASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13449">
        <property type="entry name" value="Phytase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887144" description="Phytase-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Phytase-like" evidence="2">
        <location>
            <begin position="140"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="523" mass="56809" checksum="F34BD4B84A3DFE44" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK92</accession>
    <name>W6ZK92_COCMI</name>
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        <recommendedName>
            <fullName evidence="10">Urea transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_34617</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC47879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK92"/>
    <dbReference type="STRING" id="930090.W6ZK92"/>
    <dbReference type="GeneID" id="19122597"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34617"/>
    <dbReference type="eggNOG" id="KOG2348">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023225_0_0_1"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050277">
        <property type="entry name" value="Sodium:Solute_Symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086:SF10">
        <property type="entry name" value="AGR155CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086">
        <property type="entry name" value="SODIUM/PROLINE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC47879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="57413" checksum="5A434A6AE1780466" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKG2</accession>
    <name>W6ZKG2_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
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    </gene>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964012">
        <property type="protein sequence ID" value="EUC44071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689413.1">
        <property type="nucleotide sequence ID" value="XM_007691223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKG2"/>
    <dbReference type="GeneID" id="19125382"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_77598"/>
    <dbReference type="eggNOG" id="ENOG502T00Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1611641_0_0_1"/>
    <dbReference type="OrthoDB" id="5425637at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890096" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="16730" checksum="FC4EF33269775A09" modified="2014-04-16" version="1" fragment="single">MNGPLLLSLFFPLLALAQDSSSGSSLPPPGYNGGSDNPQDPSDAGAAGSQKGAFSLSGGAVAAIIVVAVLVVLGSIASGVLWWLAKKRQWDVRASIRRASRRFTGRSTVDNKQNRSDRRTGIRLNSPPPGRNTNKMRDIEKGLPIPHKTPQTTTIITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKT7</accession>
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        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_777</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="5"/>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682807.1">
        <property type="nucleotide sequence ID" value="XM_007684617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKT7"/>
    <dbReference type="GeneID" id="19125385"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_777"/>
    <dbReference type="eggNOG" id="ENOG502SM9C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_3_1_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF32">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889914" description="AA9 family lytic polysaccharide monooxygenase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="8">
        <location>
            <begin position="20"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="352"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="501"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="501"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="518"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="531" mass="56393" checksum="C2923571EFF33493" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLD9</accession>
    <name>W6ZLD9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_21781</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682665.1">
        <property type="nucleotide sequence ID" value="XM_007684475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLD9"/>
    <dbReference type="STRING" id="930090.W6ZLD9"/>
    <dbReference type="GeneID" id="19120120"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21781"/>
    <dbReference type="eggNOG" id="KOG0371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004962_8_1_1"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="134"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC50768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="329" mass="37481" checksum="737E0812C49E9963" modified="2014-04-16" version="1">MDTNMEDVKMPEPMQLSSAPTSEPTTIPTLDGWIESLMSCKQLAESDVQRLCDKAREVLQDESNVQPVKCPVTVCGDIHGQFHDLMELFKIGGPNPDTNYLFMGDYVDRGYFSVETVTLLVALKIRYPQRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALIDNQIFCLHGGLSPSIDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEAFNHNNGLTLVARAHQLVMEGYNWSQDRNVVTIFSAPNYCYRCGNQAAIMEIDEHLKYTFLQFDPCPRAGEPMVSRRTPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM48</accession>
    <name>W6ZM48_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Pectinesterase</fullName>
            <ecNumber evidence="4 11">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_33900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in maceration and soft-rotting of plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1-&gt;4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)</text>
            <dbReference type="Rhea" id="RHEA:22380"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14573"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:140522"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pectinesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="4 11"/>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684835.1">
        <property type="nucleotide sequence ID" value="XM_007686645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZM48"/>
    <dbReference type="STRING" id="930090.W6ZM48"/>
    <dbReference type="GeneID" id="19122436"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33900"/>
    <dbReference type="eggNOG" id="ENOG502QSQ4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012243_1_0_1"/>
    <dbReference type="OrthoDB" id="2019149at2759"/>
    <dbReference type="UniPathway" id="UPA00545">
        <property type="reaction ID" value="UER00823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000014">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033131">
        <property type="entry name" value="Pectinesterase_Asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF127">
        <property type="entry name" value="PECTINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00503">
        <property type="entry name" value="PECTINESTERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005151159" description="Pectinesterase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="12">
        <location>
            <begin position="42"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC48619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="339" mass="36765" checksum="372E26CB569416A2" modified="2014-04-16" version="1">MRVTLAFLLSLIAATAAAPAEDVLRRASFDRSSAPAGCLTVGGNGKYKTVQSAVNALDKSTSKAQCIFIAKGTYTEQVYIQQLNSPLTIYGETKDTRSYTGNTVTITQRKSQDDTSSNDETATLRAHTPNFKVYNINLVNTRGQGSQALAVSAWADKQGYYGCVFKGYQDTVLAQLGNQVYAKSYIEGATDFIFGQKARAWFDGCDIGVLGAQQGWITANGRKEETNPSYYVINNSKVSHAIGATVSPGVYYLGRPWGNYARVVFQHTDLSNVINPQGWAAWNTGDARTDHVLFGEYQNTGAGASGKRAFGQTLKAALSITDILGSNYKDWVDVSYVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMJ1</accession>
    <name>W6ZMJ1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_97338</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963997">
        <property type="protein sequence ID" value="EUC44801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688698.1">
        <property type="nucleotide sequence ID" value="XM_007690508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMJ1"/>
    <dbReference type="GeneID" id="19129038"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97338"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000364">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000566">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF54">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC44801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="53813" checksum="22AAF853B6F3B5ED" modified="2014-04-16" version="1">MARDAMDDSASKDHTYIMEEVPTEKASLAGLPDHLHQAMRAGLSQEDAEFLYSVDKAEQRKIFHKVDWRLCPMLAILYLISHLDRANIGNAKIEGLEKTLGMKGTDYNVALMVFFVPYVLFEIPSNMILAKFKRPSYYMGTLTLCWGTFRMALFYCASATSGAFSGLLAAAIAKMNGIAGLEGWRWIFILEGIATVLLGASVFFLLPDSPDHAAGRWLTVDEARFLRLTHIVTRGVKRERRVNAEGKKERVKWGVIGQVVKDWQIYLQAMVFASNAVPNYGLKFTMPQILKNMGFTSTTAQLMTAPPYACGAISALVSSLLADRFTWRMPFIATGQALLIVAYAILFAKAEAIKDNVAVCYFAVHVACIGLYPILPGCNAWTINNLAGPEKRAVGIATMICIGNLGGIVGSFIFQEKESPKYETGFGSSLSFAAAGLVCAFTLEFLFFRINKRNAEKTEEEWRAIYTPAQLEKMGDRSPLFKYHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMV4</accession>
    <name>W6ZMV4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Conserved oligomeric Golgi complex subunit 6</fullName>
            <shortName evidence="10">COG complex subunit 6</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 10">Component of oligomeric Golgi complex 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_127</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as a component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the conserved oligomeric Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the COG6 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682063.1">
        <property type="nucleotide sequence ID" value="XM_007683873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMV4"/>
    <dbReference type="STRING" id="930090.W6ZMV4"/>
    <dbReference type="GeneID" id="19119828"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_127"/>
    <dbReference type="eggNOG" id="KOG3758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011361_1_0_1"/>
    <dbReference type="OrthoDB" id="272987at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010490">
        <property type="entry name" value="COG6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048369">
        <property type="entry name" value="COG6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048368">
        <property type="entry name" value="COG6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21506">
        <property type="entry name" value="COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21506:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20653">
        <property type="entry name" value="COG6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06419">
        <property type="entry name" value="COG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01087">
        <property type="entry name" value="COG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric complex COG6 N-terminal" evidence="12">
        <location>
            <begin position="59"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved Oligomeric Golgi complex subunit 6 C-terminal" evidence="13">
        <location>
            <begin position="203"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC51328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="694" mass="77035" checksum="A62E5D06726CB8BA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMW6</accession>
    <name>W6ZMW6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSM3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM3</name>
        <name evidence="11" type="ORF">COCMIDRAFT_86287</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684657.1">
        <property type="nucleotide sequence ID" value="XM_007686467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMW6"/>
    <dbReference type="STRING" id="930090.W6ZMW6"/>
    <dbReference type="GeneID" id="19126829"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86287"/>
    <dbReference type="eggNOG" id="KOG3460">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076902_5_1_1"/>
    <dbReference type="OrthoDB" id="29543at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140445">
        <property type="term" value="C:chromosome, telomeric repeat region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008266">
        <property type="term" value="F:poly(U) RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01730">
        <property type="entry name" value="LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000036">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034105">
        <property type="entry name" value="Lsm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040002">
        <property type="entry name" value="Sm-like_LSM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13110">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="9"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC48849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="96" mass="10955" checksum="5177B41EC89D57A7" modified="2014-04-16" version="1">MDEKEETNEPLDLVRLCIDEIVIVKLRGDRELKGRLHAYDSHCNLVLGDVEETIYIAEEDDDDQEPRVRTVKKQSEMLFIRGDSVVLIAPAEGTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZP29</accession>
    <name>W6ZP29_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_85071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963933">
        <property type="protein sequence ID" value="EUC49269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684233.1">
        <property type="nucleotide sequence ID" value="XM_007686043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZP29"/>
    <dbReference type="GeneID" id="19126590"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85071"/>
    <dbReference type="HOGENOM" id="CLU_2236124_0_0_1"/>
    <dbReference type="OrthoDB" id="10375936at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="112" mass="11959" checksum="0339777BF9F2A6D1" modified="2014-04-16" version="1" fragment="single">PPNAPLFIISICSSSAFAFHTPPFPPAPNLLFSHVCHPCISLIRIHALLPTIFSPQSLSVSVDLSKVTYSPPDGVKRAVIGLAPAPTFDLIDSCPWTISPPPPCQPPNLLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPN8</accession>
    <name>W6ZPN8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_95138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963981">
        <property type="protein sequence ID" value="EUC45581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687891.1">
        <property type="nucleotide sequence ID" value="XM_007689701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPN8"/>
    <dbReference type="GeneID" id="19128590"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_95138"/>
    <dbReference type="HOGENOM" id="CLU_196945_0_0_1"/>
    <dbReference type="OrthoDB" id="10409583at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="64" mass="7389" checksum="A77BA828D6779047" modified="2014-04-16" version="1" fragment="single">SLTETRCFFWFLWLHSSARLATHVEIRPRVNLHLPCAYLLTCVSIHLLLCVITSRILAKGRHAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQ86</accession>
    <name>W6ZQ86_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_76332</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687650.1">
        <property type="nucleotide sequence ID" value="XM_007689460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ86"/>
    <dbReference type="STRING" id="930090.W6ZQ86"/>
    <dbReference type="GeneID" id="19125343"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_76332"/>
    <dbReference type="HOGENOM" id="CLU_2020643_0_0_1"/>
    <dbReference type="OrthoDB" id="3690055at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="22"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC45881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="122" mass="14057" checksum="D268205509641CEB" modified="2014-04-16" version="1" fragment="single">SPRSGFLKNDTEPCTAQPTTPCPICHETITRKTPTRGLRIHIRNTKTAARMFVLTCHRTYQTKHNISSSSSSHPLLRPRTKSSRSNSMMRIKRCGHAFCYDCLETWVQKQNTCPMCRDRLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQA6</accession>
    <name>W6ZQA6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_83773</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683778.1">
        <property type="nucleotide sequence ID" value="XM_007685588.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZQA6"/>
    <dbReference type="GeneID" id="19126327"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83773"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001837_2_1_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000003">
        <property type="entry name" value="Class V chitinase CHIT5b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF2">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="4 13" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 14 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887643" description="chitinase" evidence="15">
        <location>
            <begin position="21"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="16">
        <location>
            <begin position="152"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="17">
        <location>
            <begin position="213"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="195"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC49669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1779" mass="196674" checksum="7BBD9230D55E85E1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRC2</accession>
    <name>W6ZRC2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Terpene synthase</fullName>
            <ecNumber evidence="4">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_93348</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="4"/>
    <dbReference type="EMBL" id="KI963969">
        <property type="protein sequence ID" value="EUC46226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687225.1">
        <property type="nucleotide sequence ID" value="XM_007689035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRC2"/>
    <dbReference type="GeneID" id="19128255"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93348"/>
    <dbReference type="eggNOG" id="ENOG502S2X0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042538_2_1_1"/>
    <dbReference type="OrthoDB" id="2861623at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010333">
        <property type="term" value="F:terpene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201:SF4">
        <property type="entry name" value="BETA-PINACENE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201">
        <property type="entry name" value="TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="365" mass="41928" checksum="5F74FE1F3B73A5B2" modified="2014-04-16" version="1">MDERITVTIPDLYKCFLTQEPRFNKGYQAAKLESERWLAKTCDFAPSMSKKVNACDFSFFISIAAPDAPPDRLKTLCDWGNWVFPFDDLFDSGELRTDLSTTERVLDSLMANMMGNPFTEHKLPIIKAHDDIYKRLEKGSSYGTQRRFVRAMQHYTLGVAHHVGHFTTNHIPSLEEMLSTRQLSVGVAPLYHLVEYAHEIVLPDEVFEHPVIETLERLGADFVILSNDILSYRKEEGEGCPFNMTAACRLAGYSAQEAFNILGSLLEQRYIQWDQAIHNLPSWGADIDIEVRRYIEGIQNVVQANISWSFRSQRYLGKNALEVRRTRKIDVMTTPPYLRIMDARISSLKSRCIPPTSKFDQLNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRV4</accession>
    <name>W6ZRV4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_92913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687053.1">
        <property type="nucleotide sequence ID" value="XM_007688863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRV4"/>
    <dbReference type="STRING" id="930090.W6ZRV4"/>
    <dbReference type="GeneID" id="19128171"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92913"/>
    <dbReference type="eggNOG" id="ENOG502SNBH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079943_0_0_1"/>
    <dbReference type="OrthoDB" id="20282at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039146">
        <property type="entry name" value="GPANK1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20923">
        <property type="entry name" value="BAT4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20923:SF1">
        <property type="entry name" value="G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="127"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="234" mass="25808" checksum="AC9B289A4190C04F" modified="2014-04-16" version="1">MTTSSSTHTSREQQTEDELPEDDPNISTAPFVEQRAFGRGLWKNPIQFVSSTPETQPAAASTNGKTMAEKYLAIMFPNGQPQPEPDAYPRCGICGEPVKESDQRIHYLSPAHQAALPRAPIPSAIDRTRMGLKYMEKHGFDVDARKGLGSSGQGMLFPLVPKEKRDKFGLGIDKKEHVKQKALGGASRADVSQGRLDAGKVRKLAQIEKKKHEKLQTMFYGNDEVEKYLGQLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRY3</accession>
    <name>W6ZRY3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_82230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GOT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683182.1">
        <property type="nucleotide sequence ID" value="XM_007684992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZRY3"/>
    <dbReference type="STRING" id="930090.W6ZRY3"/>
    <dbReference type="GeneID" id="19126015"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82230"/>
    <dbReference type="eggNOG" id="KOG1743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124519_1_0_1"/>
    <dbReference type="OrthoDB" id="204784at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000137">
        <property type="term" value="C:Golgi cis cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045176">
        <property type="entry name" value="Got1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493">
        <property type="entry name" value="CGI-141-RELATED/LIPASE CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493:SF9">
        <property type="entry name" value="GOLGI TRANSPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="139" mass="14964" checksum="C61A35089D8DD016" modified="2014-04-16" version="1">MPTMWLSDTQKIGVAFCSGGGLFLMGGVMMFFDRAMLAMGNILFIIGLTLIIGTTKTVAFFARKQKWKGTLAFVAGISLILMRWAFVGFIVELYGILVLFGDFLATIAGFVSNVPIIGPYIAKALQAISGATRNSDLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSP8</accession>
    <name>W6ZSP8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_81693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682874.1">
        <property type="nucleotide sequence ID" value="XM_007684684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSP8"/>
    <dbReference type="GeneID" id="19125919"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81693"/>
    <dbReference type="eggNOG" id="ENOG502T22I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_717786_0_0_1"/>
    <dbReference type="OrthoDB" id="3775616at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="389" mass="43484" checksum="543BA699B7CAAE77" modified="2014-04-16" version="1">MALRSIDSQLLLSGPVLSCESQNGECGETTPSRLLKRQRSSDKMQEKRKKSRQDSAAGSTPSCPLLVALREYGLLENVLSCLCPGDLLALLLCSKSIYQTLIPQPGSLENLLGKLRCSGKGVQIRRERHVKSSFFYAYECSEYVECGAIDGVAESRPCTNCKVTTCNECRIHCVYQSIFEKPCEDDELPNYSGFILLSPSEIPILSPHHLKDNLTTPQWQAPSPATSAPYHDQGFIDVPLEEESFGPPECVDDFLDLNLGTRTFAGPVASNVAHPSPVLRSLYQTTEGRKRRFCDDHLPSGIPKQRKDLSVHQCQCSLRSRFLDRWLCLRCYENEETTLRNTYVDHVAQCCCGSTHVREICMWCLGEISQPHTEEAQTDSENSLDEHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZT76</accession>
    <name>W6ZT76_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_80999</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates. The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site. Shows a broad primary substrate specificity. Favors hydrophobic residues at the P1 and P1' positions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682719.1">
        <property type="nucleotide sequence ID" value="XM_007684529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZT76"/>
    <dbReference type="GeneID" id="19125779"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80999"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_0_1_1"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06097">
        <property type="entry name" value="Aspergillopepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000024">
        <property type="entry name" value="Endothiapepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000026">
        <property type="entry name" value="Endothiapepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034163">
        <property type="entry name" value="Aspergillopepsin-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF23">
        <property type="entry name" value="ASPARTIC ENDOPEPTIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G15950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004890013" description="Peptidase A1 domain-containing protein" evidence="12">
        <location>
            <begin position="20"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="13">
        <location>
            <begin position="115"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC50714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="435" mass="45925" checksum="F66E6D4A3A06E164" modified="2014-04-16" version="1">MPSLRFLLFVALLAAVVLAVPAPSRKRGLQKRSFKVPRQLNKAHPTGPNGPAAMRKVFRKYNFKIREDFMVKDGFISFSKQTKGNDTATAAAAAGSSGNSSGTVAANPADNAALFLSPVDIGGQTLNLDFDSGSSDLWCFSTELDPQLIGQHTAFDPAKSATFKKVAGAQWKISYGDGSGAAGIVGMDTVTIGGVTVKNQAVELASQVSQSFVQDTNTDGLVGLAFSQLNTINDGTKKTPQKTFFANVMNDLDLPVFTADLDPDGTGVYEFGKIDATKFEGEMAWIPVKAETGFWQFGSTKFAVGDQLFDNPQGSDAIADTGTSLLLVDQQVADAYYSQVKGAQLNAQVGGFIFPCATTLPDMSVAIGDSYMAKIPGNQLIFAPVDKANTTCFGGVQGNQGSGLQIYGDTMFRAQFVAFNGGNQSLGFGQKPATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTG3</accession>
    <name>W6ZTG3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_91240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC47011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686515.1">
        <property type="nucleotide sequence ID" value="XM_007688325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTG3"/>
    <dbReference type="STRING" id="930090.W6ZTG3"/>
    <dbReference type="GeneID" id="19127842"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91240"/>
    <dbReference type="eggNOG" id="KOG2655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017718_0_0_1"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000238">
        <property type="entry name" value="Cell division control 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="24"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="314"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC47011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="381" mass="44058" checksum="477EDA86F4205255" modified="2014-04-16" version="1">MAESASPIGIANLPNQRHKIVAKRGAAFTIMVAGESGLGKTTFINTLFSTTIKNYADHKRRHHKQMDKTVEIEITKAELEEKFFKVRLTVIDTPGFGDYVNNRDSWQPIIEFLDDQHESYMLQEQQPRRTDKIDLRVHACLYFIRPTGHTLKPLDIEVMKKLCTRVNLIPVVAKADTLSPTDLAKFKMRVRQVIDAQGIKIYTPPLEDDDAAAMQHARSLIDAMPFSVIGSEKDVQTNDGRTVKGRQYAWGVAEVENEEHCDFKKLRAILIRTHMLDLIHTTEENHYEAYRAGQMETRKFGEARPRKLDNPKFKEEEEALRKRFTEQVKVEEQRFRQWEQKLIAERDRLNKDLEASHAEIKRLEGEVDALQGSINRSHGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZTP8</accession>
    <name>W6ZTP8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA topoisomerase I</fullName>
            <ecNumber evidence="7">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA topoisomerase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_80656</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="7"/>
    <dbReference type="EMBL" id="KI963920">
        <property type="protein sequence ID" value="EUC50924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682593.1">
        <property type="nucleotide sequence ID" value="XM_007684403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZTP8"/>
    <dbReference type="STRING" id="930090.W6ZTP8"/>
    <dbReference type="GeneID" id="19125706"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80656"/>
    <dbReference type="eggNOG" id="KOG0981">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009193_1_1_1"/>
    <dbReference type="OrthoDB" id="47179at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007097">
        <property type="term" value="P:nuclear migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000183">
        <property type="term" value="P:rDNA heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000019">
        <property type="term" value="P:regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009303">
        <property type="term" value="P:rRNA transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00659">
        <property type="entry name" value="Topo_IB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00660">
        <property type="entry name" value="Topoisomer_IB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.41:FF:000001">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.10:FF:000003">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.11.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.15.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.11.10">
        <property type="entry name" value="DNA Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="entry name" value="Topoisomerase I, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.41">
        <property type="entry name" value="Yeast DNA topoisomerase - domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013034">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013030">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025834">
        <property type="entry name" value="TopoI_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014727">
        <property type="entry name" value="TopoI_cat_a/b-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008336">
        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013499">
        <property type="entry name" value="TopoI_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14370">
        <property type="entry name" value="Topo_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00435">
        <property type="entry name" value="TOPEUc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52038">
        <property type="entry name" value="TOPO_IB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="DNA topoisomerase I eukaryotic-type" evidence="10">
        <location>
            <begin position="425"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="787"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="6">
        <location>
            <position position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC50924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="903" mass="102722" checksum="6F2F7BDA95360879" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZU81</accession>
    <name>W6ZU81_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial import receptor subunit Tom22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_80005</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom22 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682431.1">
        <property type="nucleotide sequence ID" value="XM_007684241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZU81"/>
    <dbReference type="STRING" id="930090.W6ZU81"/>
    <dbReference type="GeneID" id="19125582"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_80005"/>
    <dbReference type="eggNOG" id="KOG4111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094333_1_0_1"/>
    <dbReference type="OrthoDB" id="10016939at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005742">
        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd22884">
        <property type="entry name" value="TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005683">
        <property type="entry name" value="Tom22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04281">
        <property type="entry name" value="Tom22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC51099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="15939" checksum="5015427202157439" modified="2014-04-16" version="1">MVQLTEVTDEEFMREQEGPVDDEDWDTDSDSDTSSVHSVQPDETFFERLSALQDMIPASTRRSVSSKASTISSWFKSGLSMGGKTLWVVSTSALLLGVPWALAYSEEQMIVEQERAELQAQRAQNEFMAPGAPLPGQPQGAKPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUA1</accession>
    <name>W6ZUA1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable vacuolar protein sorting-associated protein 16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_24756</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686147.1">
        <property type="nucleotide sequence ID" value="XM_007687957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUA1"/>
    <dbReference type="STRING" id="930090.W6ZUA1"/>
    <dbReference type="GeneID" id="19120635"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24756"/>
    <dbReference type="eggNOG" id="KOG2280">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008909_1_0_1"/>
    <dbReference type="OrthoDB" id="1792at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000635">
        <property type="entry name" value="Probable vacuolar protein sorting-associated protein 16 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.780">
        <property type="entry name" value="Vps16, C-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016534">
        <property type="entry name" value="VPS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006925">
        <property type="entry name" value="Vps16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038132">
        <property type="entry name" value="Vps16_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006926">
        <property type="entry name" value="Vps16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04840">
        <property type="entry name" value="Vps16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04841">
        <property type="entry name" value="Vps16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007949">
        <property type="entry name" value="VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps16 N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Vps16 C-terminal" evidence="3">
        <location>
            <begin position="501"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR007949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC47271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="839" mass="94276" checksum="376B74421A94CD12" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUI5</accession>
    <name>W6ZUI5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate esterase family 5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_31734</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682380.1">
        <property type="nucleotide sequence ID" value="XM_007684190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUI5"/>
    <dbReference type="GeneID" id="19121945"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31734"/>
    <dbReference type="eggNOG" id="ENOG502RZTY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040058_6_2_1"/>
    <dbReference type="OrthoDB" id="3225429at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF9">
        <property type="entry name" value="CUTINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887715" evidence="3">
        <location>
            <begin position="21"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC51174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="235" mass="24782" checksum="8B222ACDBF621633" modified="2014-04-16" version="1">MHYTSTTPLLAFALIALSSAQETCPAIPPNDVEIGQPVPIVPGDIPKGCSAFEILVETDVSNPARGTSEPSFPKFGVIVGDPVVSNVSAQLPGVQGYPVQYPASSQVVTGGRQGTDDIVKRLTTQSAACPNQTFALVGYSQGASIMHRAAEKLPVSLFPRIKAVVMFGDPQQGLGALGDKFPIGLRPKVLQVCAKGDPVCDSGSCQYYHLTYVLPKLMDPAVAFIVRAFQGSPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUX1</accession>
    <name>W6ZUX1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_21358</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682108.1">
        <property type="nucleotide sequence ID" value="XM_007683918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUX1"/>
    <dbReference type="GeneID" id="19120049"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21358"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024886_0_0_1"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13738">
        <property type="entry name" value="Pyr_redox_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC51384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="59059" checksum="6CB35324ED885718" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZZA4</accession>
    <name>W6ZZA4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 8 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_85670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684457.1">
        <property type="nucleotide sequence ID" value="XM_007686267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZZA4"/>
    <dbReference type="STRING" id="930090.W6ZZA4"/>
    <dbReference type="GeneID" id="19126706"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_85670"/>
    <dbReference type="eggNOG" id="KOG1950">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049943_1_0_1"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000228">
        <property type="entry name" value="Galactinol synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="418" mass="47538" checksum="93DC77D3682B768B" modified="2014-04-16" version="1">MADNSRHGGPPSKNAYVTLLTRPSYLAGAILLAYTLHKHSPSTPLIICYTPDTLPESSVTAFAAEAKYSDIILQPVEHLRLPEDGTAHGMVAERFIDTWTKLRVFDLWDMPQKWERLCWLDADMMIFSDPSPLVFNAQNDEYLIGGDGMRTMAVHTCVCNLDHDAWAPAEWTKENCAMTPLTSPDQLAQVKSEPYTLTNFNSGTFLYRPSKQLADFVQQKFEELGNARLRAMKFPDQDFLNEAFDGRWAPLSWRTNALKTWRYWHTNIWTDDSYVAVLHYIVDKPWAARNKPDGSAGYLGKDGETHKWWWDEFEVWRREREEQGERELLEVVEKYVANKDGKANEEMKAIGGGAQDFAKKWDTKEKENEDGASKEGGGLKLSDDAQKKADEYGQGPHGPILRKPMLGERGHGPVVHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>W6YJQ4</accession>
    <name>W6YJQ4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_10320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964312">
        <property type="protein sequence ID" value="EUC39602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693879.1">
        <property type="nucleotide sequence ID" value="XM_007695689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YJQ4"/>
    <dbReference type="GeneID" id="19118245"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10320"/>
    <dbReference type="HOGENOM" id="CLU_3124726_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <source>
            <dbReference type="EMBL" id="EUC39602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="50" mass="5427" checksum="A3295A92008C4061" modified="2014-04-16" version="1">MVRKRIDCLVASIVSSIYSSYAHGPIGGDNASASARVDQSVSRIKREVYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YL54</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EUC39927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YL54"/>
    <dbReference type="GeneID" id="19117754"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10084"/>
    <dbReference type="HOGENOM" id="CLU_1045809_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="266" mass="28701" checksum="3D4FC7B2AB25A11F" modified="2014-04-16" version="1">MPPPPPRSMPSPSHTVPPPPTPTAPSSTPVPATAGYSHTIPLLPPSGIPPELFDYAVGCAVDCAVRHVVNDAVDHAVNRAVDRAIDDIYDLHVGRQDWSEHGTVRLTSVQHAMLSKTSPSQWKGFGPIDMELLDLSGRLCFTQHCGDSPASSFVENLLRVTQDMAGKTQEGSSLYWNHSVVLFLNKRVKVEVDGKSHSGLFVGATTLETPGGPPLPFGVYRIQLSGSTELILDLLKSGIDGTWIHELSETANETVDNEGFEEMTDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQD5</accession>
    <name>W6YQD5_COCMI</name>
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        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 43 protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="7" type="ORF">COCMIDRAFT_10134</name>
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    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC39865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693614.1">
        <property type="nucleotide sequence ID" value="XM_007695424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQD5"/>
    <dbReference type="STRING" id="930090.W6YQD5"/>
    <dbReference type="GeneID" id="19117856"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10134"/>
    <dbReference type="eggNOG" id="ENOG502QVC0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016508_1_1_1"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09001">
        <property type="entry name" value="GH43_FsAxh1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF15">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889311" evidence="5">
        <location>
            <begin position="20"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="6">
        <location>
            <begin position="342"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC39865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="550" mass="59626" checksum="41AB20E6C7A6B6DB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQY1</accession>
    <name>W6YQY1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_40014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964083">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQY1"/>
    <dbReference type="STRING" id="930090.W6YQY1"/>
    <dbReference type="GeneID" id="19123789"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40014"/>
    <dbReference type="HOGENOM" id="CLU_458545_0_0_1"/>
    <dbReference type="OrthoDB" id="3785839at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="572" mass="65140" checksum="9DDAE1EF42FC66E3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YQZ5</accession>
    <name>W6YQZ5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_8489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964083">
        <property type="protein sequence ID" value="EUC41862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691618.1">
        <property type="nucleotide sequence ID" value="XM_007693428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YQZ5"/>
    <dbReference type="GeneID" id="19126560"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8489"/>
    <dbReference type="eggNOG" id="ENOG502T6K0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105525_0_0_1"/>
    <dbReference type="OrthoDB" id="3794829at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC41862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="228" mass="25249" checksum="DBBC8D15B030D26B" modified="2014-04-16" version="1">MCLYWKKMHTCGHLSDRPYIEMCRPGLLSNNVCLDIKDDEQCRPSHFPCYFCIKAEARAEIEAQVRSDQEAIAKARQARENAVKEKVAAEMRAKEERVRREAREKATREREAEQRAKQEKEEDEIRAKKEGGPWIETLGGKKFKGKRNAGGSGTMGSPTRLLNSLSVAKMATGPKNTKENSSGNGDGGEMMGSKTVSVDMGGRAGVWGPKKILTRQENDVGTGSGTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR65</accession>
    <name>W6YR65_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TrmE-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_9936</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964195">
        <property type="protein sequence ID" value="EUC40125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693353.1">
        <property type="nucleotide sequence ID" value="XM_007695163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR65"/>
    <dbReference type="STRING" id="930090.W6YR65"/>
    <dbReference type="GeneID" id="19129455"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9936"/>
    <dbReference type="eggNOG" id="KOG1191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019624_3_0_1"/>
    <dbReference type="OrthoDB" id="188276at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14858">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="entry name" value="tRNA modification GTPase MnmE domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42714">
        <property type="entry name" value="TRNA MODIFICATION GTPASE GTPBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42714:SF2">
        <property type="entry name" value="TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP-binding protein TrmE N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="MnmE helical" evidence="3">
        <location>
            <begin position="122"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="222"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC40125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="53973" checksum="E8930F1D59B449FD" modified="2014-04-16" version="1">MSHSEMLNAYQIYQGLCPSTEFPKPRHATLRRLYAPHLPPSPATILDSGALVLYFPAPKTVTGEDVLELHVHGGPAVVRAVLAAIPECGTVSGTPAFKRSQIRYAEPGEFTRRAFANNRMNLPQIESLGETLSASTEQQRKLSVRGTTSSLAKRYEKWRRLLLEARGELEALIDFSEDQHFDESPAALCASVASQVQVLSTQMEAHISNAVRGELLRNGISVALLGAPNAGKSSLLNRIVGRDAAIVSQEAGTTRDVVEVGLDLGGWLVKIGDMAGLRRAGLVGGDVVGAVEQEGIRRAKQRALESDVLIVVQDATADMDVEVMETAKQCVDVGINVIVAINKSDQISALDAAQRRWKQKVHSALGLPEDRTCFISCKEVTAGNIPAFLTTLQDIFKSMTTALVPDSDPDPDPSIWQESLGATERQRLLLAECLGHLSAFLTTVDSSSAAACATDEEIDGEADEVDIVVAAECLRSAADALARITGRGESGDVEEVLGVVFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRI0</accession>
    <name>W6YRI0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PABS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_29242</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964074">
        <property type="protein sequence ID" value="EUC42057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691402.1">
        <property type="nucleotide sequence ID" value="XM_007693212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRI0"/>
    <dbReference type="GeneID" id="19121467"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29242"/>
    <dbReference type="eggNOG" id="ENOG502QTVA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017511_2_0_1"/>
    <dbReference type="OrthoDB" id="2016285at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000288">
        <property type="entry name" value="Spermine/spermidine synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037959">
        <property type="entry name" value="MFS_SpdSyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF59">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="63536" checksum="C37F5BF34F860386" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRK5</accession>
    <name>W6YRK5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_9939</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
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    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000061">
        <property type="entry name" value="MFS sugar transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
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    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
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        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="16"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="514"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="549" mass="60587" checksum="FE08066F6892C147" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YSC0</accession>
    <name>W6YSC0_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_39612</name>
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    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964065">
        <property type="protein sequence ID" value="EUC42337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YSC0"/>
    <dbReference type="STRING" id="930090.W6YSC0"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_39612"/>
    <dbReference type="eggNOG" id="ENOG502SIA0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_411114_0_0_1"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
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    </dbReference>
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        <property type="entry name" value="POZ domain"/>
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    </dbReference>
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        <location>
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            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="775" mass="85558" checksum="D272C31D8CB1E42C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTG3</accession>
    <name>W6YTG3_COCMI</name>
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        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="6" type="ORF">COCMIDRAFT_28657</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
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        <property type="protein sequence ID" value="EUC42742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692525.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19121347"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28657"/>
    <dbReference type="eggNOG" id="KOG4231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110090_0_0_1"/>
    <dbReference type="OrthoDB" id="5430240at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC42742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="166" mass="18393" checksum="B758654F2D02EB3F" modified="2014-04-16" version="1">MSHDDADLFSVSSFVRATMVNGSIQRLRSYPSTTEEPFDFTIWEAARATSAAPTFFAPIKFPNGMDFRDSGFGANNPIFELINEIRKEFPTKDISTIVSLGTGVSSSMKLGRGLVSVAEAYSKIAMNTKKTAESFEAQYSHQQGIYRHKYFHFNPTNGLQGVGLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTT7</accession>
    <name>W6YTT7_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_107492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964129">
        <property type="protein sequence ID" value="EUC40948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692535.1">
        <property type="nucleotide sequence ID" value="XM_007694345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTT7"/>
    <dbReference type="STRING" id="930090.W6YTT7"/>
    <dbReference type="GeneID" id="19119059"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107492"/>
    <dbReference type="eggNOG" id="ENOG502RHJM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038732_9_0_1"/>
    <dbReference type="OrthoDB" id="2349068at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF34">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="344" mass="36118" checksum="89034C43D34A0F82" modified="2014-04-16" version="1">MSTLTSHLPWTVSPLLINAPMSGFAGGHLAAAVSLAGGLGLIGGVRDMREVRRELDIAAELLGQTRGEGTMKVGVGFLPFAMELAEVLDVVREYKPAVVWLFAAKTLGAYKEWVDAVRSVSPEIRVWVQLGSVAAAMEVAREATPDVLCLQGADAGGHGFEKGASIVSLVPEATNALAAAGFADIALVASGGIVDGRGVAAALALGAQGVVMGTRFLASSEVKVHPKYQAAILEAQDGGQVTTRSKLFDQLRGPNIWPELYDGRGLVAQSHRDFASGMSLEEIQKLHNQEVAGEDKGYDTGLQGRAAIWAGTGVGLVNEVQSAKDIVDKIRKETKDVLLRVANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUH4</accession>
    <name>W6YUH4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <ecNumber evidence="3 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_106870</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="3 7"/>
    <dbReference type="EMBL" id="KI964116">
        <property type="protein sequence ID" value="EUC41180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692318.1">
        <property type="nucleotide sequence ID" value="XM_007694128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUH4"/>
    <dbReference type="STRING" id="930090.W6YUH4"/>
    <dbReference type="GeneID" id="19118937"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106870"/>
    <dbReference type="eggNOG" id="KOG3243">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089358_2_0_1"/>
    <dbReference type="OrthoDB" id="2965at2759"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.960:FF:000005">
        <property type="entry name" value="6,7-dimethyl-8-ribityllumazine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="entry name" value="Lumazine/riboflavin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058:SF0">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE DMRL SYNTHASE LUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="Lumazine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="208" mass="21957" checksum="78D440571A9D278A" modified="2014-04-16" version="1">MASLKGPGAPKTYDGSGLRIGIVHARWNTKIIDALLEGTRKKLREAGVKDENIVVQDVPGSYELPYAVKQLYSASQIQSSNTGVVGAAADLLGSTSDLTALTGQSAAKVSNQPFDAIIAIGVLIKGETMHFEYIADAVSHGLMRLQLDNNVPVIFGLLTLLSDEQGLMRAGIGGSDGKSGHNHGEDWGSAAVELGVKRKGWVEGKFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6YV46</accession>
    <name>W6YV46_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bms1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_101193</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964033">
        <property type="protein sequence ID" value="EUC43317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690178.1">
        <property type="nucleotide sequence ID" value="XM_007691988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YV46"/>
    <dbReference type="STRING" id="930090.W6YV46"/>
    <dbReference type="GeneID" id="19117826"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_101193"/>
    <dbReference type="eggNOG" id="KOG1980">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009858_1_0_1"/>
    <dbReference type="OrthoDB" id="119302at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
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    </dbReference>
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        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <location>
            <begin position="89"/>
            <end position="248"/>
        </location>
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        <location>
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        </location>
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            <end position="343"/>
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        </location>
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        </location>
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    </feature>
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    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC43317.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="802" mass="90455" checksum="374A4AF672277A91" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVG0</accession>
    <name>W6YVG0_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
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        <name evidence="2" type="ORF">COCMIDRAFT_38671</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="26634" checksum="C19DE0A18951EF9C" modified="2014-04-16" version="1">MARILITGSSDGLGLAAAQRLISQGHTVVLHARNPQRASDATTACPGAETVVTGDLSSLSETKALAAQVNNLGTFDAVIHNAGLFRGPLRKTSEGIPALAAVNTIAPYVLTALINRPKRLVFLSSEMHKYANKEEDLDDPLWKTRRRGLHNVMFAKAFARRWPEVRSNALDPGWVATKMGGSSAPESIDAAVESYVMLAVGEEAEKKSGCYFHPSKREGKPLEAAEDEKAQDRLLEVCAEFSGVRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVZ8</accession>
    <name>W6YVZ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="2">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_105490</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
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        <property type="protein sequence ID" value="EUC41703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693601.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6YVZ8"/>
    <dbReference type="GeneID" id="19118690"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105490"/>
    <dbReference type="eggNOG" id="KOG0169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002738_3_0_1"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF82">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="5">
        <location>
            <begin position="398"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="507"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="170"/>
            <end position="199"/>
        </location>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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        <location>
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            <end position="18"/>
        </location>
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            <begin position="19"/>
            <end position="229"/>
        </location>
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            <begin position="17"/>
            <end position="176"/>
        </location>
    </feature>
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        <location>
            <begin position="187"/>
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        </location>
    </feature>
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            <end position="203"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC42045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="229" mass="23685" checksum="DB8014B91D15576F" modified="2014-04-16" version="1">MLSKTLFVAAAMVAGVNAHFRLLEPFWRGSSFAAPASQYIYPCANVNETTDVSNRTVWPVTGGSTLINGSHEHALTAINLALGTNVTNFNISLVEMFNQTGTGLFCLKETGRANLEAGFKAAGYSGFDDQRINGLLGTIQVIQLGHSGSALYNCADIRFNSTAQLLSDDQCQNSTGVSGVAITNVGSESQNGGANGTSGQAPQPTGAAGHISPALGTAVFAAVLAWGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6YX05</accession>
    <name>W6YX05_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_104531</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">ATCC 44560</strain>
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    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC42053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="705" mass="79551" checksum="A55643DFC732EA31" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYF5</accession>
    <name>W6YYF5_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">COCMIDRAFT_103105</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502SI2I">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="651"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="713" mass="78808" checksum="BF0BB599E43E1691" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYH6</accession>
    <name>W6YYH6_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">CorA-like transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">COCMIDRAFT_39361</name>
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    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964055">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007692684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYH6"/>
    <dbReference type="STRING" id="930090.W6YYH6"/>
    <dbReference type="GeneID" id="19123670"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39361"/>
    <dbReference type="eggNOG" id="ENOG502SJEH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025521_1_0_1"/>
    <dbReference type="OrthoDB" id="5396681at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058257">
        <property type="entry name" value="CorA-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26616">
        <property type="entry name" value="CorA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="CorA-like transporter" evidence="3">
        <location>
            <begin position="10"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="537"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC42620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="594" mass="68690" checksum="984318EC7D2E1DEA" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYW2</accession>
    <name>W6YYW2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_28680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964050">
        <property type="protein sequence ID" value="EUC42768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690718.1">
        <property type="nucleotide sequence ID" value="XM_007692528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYW2"/>
    <dbReference type="GeneID" id="19121351"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28680"/>
    <dbReference type="eggNOG" id="ENOG502SVGN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_621100_0_0_1"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="441" mass="50739" checksum="6F988F76712C64B0" modified="2014-04-16" version="1">MTTPVAFSCWSLESLKAPYLPLTLDEYCCSTLPKSMLDRRNRDQVLYKAKNTNSNSKELVTICQLWILQCEDGLITAHETDEELNTNGSKSDFPSWGDDCLTGDAKRYIGIMMSHFVDSLDRPSETGSGNRILNTFENSIASCAHDVDEYSRGEVVKKFDIDKEREFLHNIDDIRGELGMIKRAILQQEEVWKTFASNAWPEHWTTGAEGRLIVKDDEQRSTAEENEWQIILRAQFQFDRFRRRIAQLDEDAARVEKSIMAKLDLKQKHASLQESHATGVMSAAVLGFTLITIIFTPLSFLTSLFALSIDSFQRNQIDFFIPNRENEADLTNRTRVYTANYIGKWAVLASTAVALLSMWLVIEYGMDVPVLRHRLAQLVKLSRRMLGLPKLIWESQYLKKVSEQVKLKVFREKGGCLPSFGGAQRTIWYTRLKLWWRRRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYX2</accession>
    <name>W6YYX2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_97877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964002">
        <property type="protein sequence ID" value="EUC44562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688961.1">
        <property type="nucleotide sequence ID" value="XM_007690771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYX2"/>
    <dbReference type="GeneID" id="19129141"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_97877"/>
    <dbReference type="eggNOG" id="ENOG502S0RS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_470230_0_0_1"/>
    <dbReference type="OrthoDB" id="3902588at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="2">
        <location>
            <begin position="397"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="606" mass="66203" checksum="2FE3AEF11F952DF2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YYY3</accession>
    <name>W6YYY3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipase B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964049">
        <property type="protein sequence ID" value="EUC42780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690690.1">
        <property type="nucleotide sequence ID" value="XM_007692500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YYY3"/>
    <dbReference type="ESTHER" id="cocmi-w6yyy3">
        <property type="family name" value="Canar_LipB"/>
    </dbReference>
    <dbReference type="GeneID" id="19123630"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39192"/>
    <dbReference type="eggNOG" id="ENOG502QSW8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029537_0_1_1"/>
    <dbReference type="OrthoDB" id="4605274at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053228">
        <property type="entry name" value="Stereospecific_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37574">
        <property type="entry name" value="LIPASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37574:SF1">
        <property type="entry name" value="LIPASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889380" description="Lipase B" evidence="1">
        <location>
            <begin position="20"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="51279" checksum="84A511EF6857992B" modified="2014-04-16" version="1">MRFFVSSLALLSIISQSLAVPAAIAQPSIEDATKTIEERQLLPDLLPGLLPGVVSLVKGLLTDVNVAVAEGKPQEVLNILQKLQPTTRPTNIQEAVAAHAKIWAIPTTRTDFFAAVATQIAGGLILDETLQTALNNALPVGENAIKNNNPDSASSIYPKKDATDAPYTLSESTLRQAIFIPSSFTYGAKRPVILVPGTATYGGTNFASNLRKLLTGKDFADPVWLNIPGAMLNDTQTNAEYIAYAINYISAISRQNQQNIAVVTWSQGGLDTQWVLKHWPSTRQVVKDFLPVSPDFKGTIFANALCLTPNSDISLLPCSASVVQQQATSDYIRSLRTNGGDSAYVPTTSFYSGFFDEIVEPQQGTSASAYMNDARNVGVTNIEVQRVCAGQPAGSFYGHSSLLSNPLTYALIVDALQQDGPGDLSRIDLKRVCSTLATPGLDLNDVLATIGLIPVSGALLLLDPTTKTFVEPPLRAYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZ63</accession>
    <name>W6YZ63_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAC3/GANP/THP3 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_102351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF4">
        <property type="entry name" value="PANTOTHENATE TRANSPORTER FEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="33"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC44757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="478" mass="52342" checksum="92AA1AEB18765560" modified="2014-04-16" version="1">MGVLGSSKSSNGDASKVMERKLIIKLGVFTTAPMVYCCACYFFNYLDRQAFANAYVAGLREDLSLKKNEYNILLSMYTSGLVVGAIPHSLIIQKIRPSIWLPLTLILWSGLTMCSAACKNYSQLCAVRFFQGLMEASLYSGTMYVMGSWYKPSEIAKRVAIFTAIGQAGSMFAGLMMTAMHKTMSGTAGLKGWQWVFIIDGLMGIPFGLFGFFTFPDLPATANVYYLSEEEKQFAASRLPPKKANTHSISPKSLLKRVLGKPHIYILTWFAVTCGMLEAFAFQGMFLLWLKYNAKRFSQTAINTYPLGTQAVAIVSQISAGFIIDRTGQRLPMVIIGALLQLVTAALLLVRNLSDAGVFTAFYISGTSFVVNPIMFSWANEICSRSGDDAARSVVLYVMSMGGQLLYTWWGIVLYPATDVPYWKKGSITMIVVCGVFIGTAFVVRWLDRNTAVVTDDETVASGDGTSATVIGEAPKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZN7</accession>
    <name>W6YZN7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Anaphase-promoting complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_60772</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964041">
        <property type="protein sequence ID" value="EUC43048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690437.1">
        <property type="nucleotide sequence ID" value="XM_007692247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZN7"/>
    <dbReference type="STRING" id="930090.W6YZN7"/>
    <dbReference type="GeneID" id="19124823"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_60772"/>
    <dbReference type="eggNOG" id="ENOG502RZA9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037984_0_1_1"/>
    <dbReference type="OrthoDB" id="2122982at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16494">
        <property type="entry name" value="RING-CH-C4HC3_ZSWM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039903">
        <property type="entry name" value="Zswim2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21540:SF0">
        <property type="entry name" value="PHD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21540">
        <property type="entry name" value="RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="152"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="27981" checksum="752CB003FAD30AAA" modified="2014-04-16" version="1" fragment="single">RAPPPKKSKRDPDAPVQEKRARIFRKRAPQSYLDVRERALTQRLTVLSRERCGTDDAPEEKVLIAGSTGNVYTVSIGLKPSCDCPHARKGNQCKHVVYVMLRVLKAREEIAYQLALVSSELREVMRNAPPIPGTDTEKQGEDGNRKPIEGECPICYDDLDAKEDTVYCKTSCGNNIHKVCMQNWVAAARNNATCPYCRAKWDTDAVLASKVGNINTSGLQRNEEGYINVASQLGLPGYRDYSTYYGGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1P5</accession>
    <name>W6Z1P5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_40264</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UTP23/FCF1 family. FCF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964096">
        <property type="protein sequence ID" value="EUC41569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691906.1">
        <property type="nucleotide sequence ID" value="XM_007693716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1P5"/>
    <dbReference type="STRING" id="930090.W6Z1P5"/>
    <dbReference type="GeneID" id="19123850"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40264"/>
    <dbReference type="eggNOG" id="KOG3165">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081098_0_1_1"/>
    <dbReference type="OrthoDB" id="76105at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd09864">
        <property type="entry name" value="PIN_Fcf1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000019">
        <property type="entry name" value="U3 small nucleolar RNA-associated protein 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037503">
        <property type="entry name" value="Fcf1_PIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="PIN" evidence="6">
        <location>
            <begin position="67"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC41569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="196" mass="22348" checksum="F13B2041D1F8DBD3" modified="2014-04-16" version="1">MGVAKKTRKFATTKRIVGQRDARLKKNQMAGEIEAKKKEEENKAKREIPQVSSALFFQANTALGPPYSVLVDTNFLSHTVHAKLELDKALMDLLYAKATPIITTCVMAELEKLGPKYRIALRIARDERWQRLKCDHKGTYADDCIVDRVQKHRIYLVATNDRDLKRRIRKIPGVPIVSVAKGKYVIERLPDVPDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2J0</accession>
    <name>W6Z2J0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_29437</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964083">
        <property type="protein sequence ID" value="EUC41859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691621.1">
        <property type="nucleotide sequence ID" value="XM_007693431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2J0"/>
    <dbReference type="GeneID" id="19121505"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29437"/>
    <dbReference type="eggNOG" id="ENOG502SV0G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061867_0_0_1"/>
    <dbReference type="OrthoDB" id="3648173at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF157">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="50"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="369"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC41859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="397" mass="43910" checksum="D5CF2C03D89A9FD8" modified="2014-04-16" version="1">MSIALDGTEFQPTITQPIVNVEAGDATNGFKTALAVEVPLMVLAISTVVLRVYSRLAIKKKLAADDILILLGTGAAFARTVLSCMSAEDNWGYDRKGPDRTSEVPYYQHIFERRIAYLFAVTFTRFSVLAYYLRIFPPGMASLRKCCYILLAMALALFIEVLTVLIVYCENISKLWTDDWLDFTGSQCFSSAVYSYSAAIGDSIIDSMIFALPIVYVWQLSKLKLRQRLGLVVIFGLGLTVCVVALLQIPFIKRRESNMQYFGSAVNILISIQISFAIIAASLPDLRALIARQFPHFSPLHHRSLATSVGRHPSGGSERGRIGVWDAEQGSPSQGVPAENARATPVGKRVFRKPDWLRNSIPASLMSTMITQNEVTRDSTEEPPVPPRIPEKVKAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2R0</accession>
    <name>W6Z2R0_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_104777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964079">
        <property type="protein sequence ID" value="EUC41939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691526.1">
        <property type="nucleotide sequence ID" value="XM_007693336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2R0"/>
    <dbReference type="STRING" id="930090.W6Z2R0"/>
    <dbReference type="GeneID" id="19118567"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104777"/>
    <dbReference type="HOGENOM" id="CLU_141125_0_0_1"/>
    <dbReference type="OrthoDB" id="3766782at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889487" evidence="2">
        <location>
            <begin position="21"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC41939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="114" mass="12556" checksum="8A1FE6DB9A181049" modified="2014-04-16" version="1">MRFNAVIASAILAATVSSAALPVPAEAAEKREAEPQLPTWPRPYGLPYGMAAEKREAEAEPQVPTWDRPYGFPHGMAAEKREAEAEPQLPTWPRPYGLPYGMAAEKRQPEALEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2R6</accession>
    <name>W6Z2R6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_6585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964013">
        <property type="protein sequence ID" value="EUC44023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689427.1">
        <property type="nucleotide sequence ID" value="XM_007691237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2R6"/>
    <dbReference type="GeneID" id="19125011"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6585"/>
    <dbReference type="HOGENOM" id="CLU_1758498_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="148" mass="16091" checksum="7C5BEDE8C4088334" modified="2014-04-16" version="1">MFRPSSAGTEDSTKCQPRRSSQLIRACSAASDTVHLPSGSIHREAVPSSYPPLILEPASLGSRAPVPAAFVSLQQYTKDMFTSINMVSRYCHMMTATFVDLRPADAVLLWLTGAPSHQDHPAASIPRAKAFSMQLHGHYTRYSGAMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2W0</accession>
    <name>W6Z2W0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_6425</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689220.1">
        <property type="nucleotide sequence ID" value="XM_007691030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2W0"/>
    <dbReference type="GeneID" id="19124958"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6425"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="VerF-like"/>
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        <source>
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            <dbReference type="ARBA" id="ARBA00023242"/>
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            <dbReference type="PROSITE" id="PS50157"/>
        </source>
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        <source>
            <dbReference type="EMBL" id="EUC44260.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="973" mass="108339" checksum="6DC7852734E37CE5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z310</accession>
    <name>W6Z310_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_104562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="entry name" value="P-loop_NTPase"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC42049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="36416" checksum="680D89615BA5A668" modified="2014-04-16" version="1">MPGAISCDAPAEGICGIYHITHPRSASNLFQKMMGQQPGFQYSSYKLFGAGFGALTQLQRGPLGSWPEEDREKLFGVFEAGFEGMIEEVEGAVGSGKKVFMKEHAVFLSAADKLLGRIYKDDNVAPLVLHERGVAPSKSSHTNPTSLPDSFLLKFQPIFQIRNPILMFPSLVRAQMDVKVAGRPRDPICQIMLQLRDSRTLYDWYAAQTTHTGITPRVIDADDVMNDAASMRKLCLQTGLDPDAIVYEWEERVVEDPMQARFLSTLAKSKGVVKGLDAKGKSVEGEMEKWVEEFGREDAEELARSVEKAMGDYEYMYSRRTVAGETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z352</accession>
    <name>W6Z352_COCMI</name>
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        <recommendedName>
            <fullName evidence="8">SPX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_98951</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EUC44153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007691136.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="19129364"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98951"/>
    <dbReference type="eggNOG" id="KOG1161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4580">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_249242_0_0_1"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033254">
        <property type="term" value="C:vacuolar transporter chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22647">
        <property type="entry name" value="CTF3_NTD_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07892">
        <property type="entry name" value="PolyPPase_VTC2-3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14480">
        <property type="entry name" value="SPX_VTC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.100.30:FF:000002">
        <property type="entry name" value="Vacuolar transporter chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012485">
        <property type="entry name" value="CENP-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF2">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 3 COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07778">
        <property type="entry name" value="CENP-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1397"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1422"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1462"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="702"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="788"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1261"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="809"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1299"/>
            <end position="1318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
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                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Dhillon B."/>
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                <person name="Han J."/>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Salamov A."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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            <dbReference type="ARBA" id="ARBA00022837"/>
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            <dbReference type="EMBL" id="EUC46507.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="18">
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            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="626" mass="70288" checksum="168E8DB1D8667A23" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4C4</accession>
    <name>W6Z4C4_COCMI</name>
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        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_7948</name>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="515"/>
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        </location>
    </feature>
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        <location>
            <begin position="104"/>
            <end position="541"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="13"/>
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        </location>
    </feature>
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        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="553" mass="60801" checksum="6AF346A978FCAAAB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4J8</accession>
    <name>W6Z4J8_COCMI</name>
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        <recommendedName>
            <fullName evidence="15">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="13" type="ORF">COCMIDRAFT_7917</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964058">
        <property type="protein sequence ID" value="EUC42539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690941.1">
        <property type="nucleotide sequence ID" value="XM_007692751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4J8"/>
    <dbReference type="STRING" id="930090.W6Z4J8"/>
    <dbReference type="GeneID" id="19125435"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7917"/>
    <dbReference type="eggNOG" id="KOG0056">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_6_3_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18583">
        <property type="entry name" value="ABC_6TM_HMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000287">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF503">
        <property type="entry name" value="MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="284"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="594"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="834"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="835"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="859"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC42539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="886" mass="98656" checksum="74185BC4DA8975CE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5R5</accession>
    <name>W6Z5R5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Beta-xylanase</fullName>
            <ecNumber evidence="10">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_26516</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="10"/>
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        <property type="protein sequence ID" value="EUC45305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007689989.1"/>
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    <dbReference type="GeneID" id="19120942"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26516"/>
    <dbReference type="eggNOG" id="ENOG502RWXU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="3055998at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF35">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889737" description="Beta-xylanase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="12">
        <location>
            <begin position="24"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC45305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="355" mass="39190" checksum="86B581CC3CBD2B31" modified="2014-04-16" version="1">MHFSILTTALALASIASGTPLSVRQTANALDAAFRARGRSYIGTSLTIRNDNTEQNIIRSSEFGSITPENAMKWDATEPNRNQFNWGNADAVANFATQNGKQMRCHTLVWYSQLPGWVNQINNNATLMSVMENHIKQVMGRYRGKCTHWDVVNEALNEDGTNRDNVFLRLIGEQYMPIAFRMAAAADPSAKLYYNDYNLEYGSAKHAGALRIVKLIQSWGLRIDGVGLQGHLVSEPTNTASQVTPSVQVLTKVLQDYADLNVDVAYTELDIRSKNPSTSQKLADAAAAWARVAQSCINVQRCIGMTVWGVADKYSWVPGTFNGEGSALLWNDNFQKKPAYTAFLDVLNGKNVTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5Z2</accession>
    <name>W6Z5Z2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_5394</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
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    </evidence>
    <sequence length="934" mass="104342" checksum="406632CBD8B5D1FE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7N1</accession>
    <name>W6Z7N1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_34790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963949">
        <property type="protein sequence ID" value="EUC47722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685757.1">
        <property type="nucleotide sequence ID" value="XM_007687567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7N1"/>
    <dbReference type="STRING" id="930090.W6Z7N1"/>
    <dbReference type="GeneID" id="19122640"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_34790"/>
    <dbReference type="eggNOG" id="KOG1432">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019692_4_1_1"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000054">
        <property type="entry name" value="DCR2p Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="218"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="552" mass="62486" checksum="13802127FF845CBC" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7N3</accession>
    <name>W6Z7N3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_5016</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687651.1">
        <property type="nucleotide sequence ID" value="XM_007689461.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z7N3"/>
    <dbReference type="GeneID" id="19124466"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5016"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_0_1"/>
    <dbReference type="OrthoDB" id="3681257at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000019">
        <property type="entry name" value="Polyketide synthase type I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="9">
        <location>
            <begin position="24"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="10">
        <location>
            <begin position="985"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="2323"/>
            <end position="2404"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="7">
        <location>
            <begin position="985"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="7">
        <location>
            <begin position="1141"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="7">
        <location>
            <position position="1017"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="7">
        <location>
            <position position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC45778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="2419" mass="265241" checksum="413E741F87689D6A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z831</accession>
    <name>W6Z831_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_6875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964021">
        <property type="protein sequence ID" value="EUC43709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689751.1">
        <property type="nucleotide sequence ID" value="XM_007691561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z831"/>
    <dbReference type="GeneID" id="19125110"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6875"/>
    <dbReference type="eggNOG" id="ENOG502TGYW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047857_0_0_1"/>
    <dbReference type="OrthoDB" id="3777651at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="332" mass="36791" checksum="41E52DE997E2B4FE" modified="2014-04-16" version="1">MDAERSKNASHSKTTKVSLTKTTLPAKSTSAPQKDKGVSEFTRGCGDAATLLSVKLHLSPRNGVKKSHGERASDTHPLNVAFKNASSDYRRHLYQTASLKTNNILKSLLTTLHESIPQTVLPSGSSKNASTSPLKFEGQVVSFDQTLEIRMLHYEALIAAQTEEVTELQKAWQAVVGEIRKLGAVYLGEKAMQDLLFAPTTGQQQGPDDSAAPLQPQYSSSPSKSTDVESTLFVPEHGISPLSKQKKYKYGASNPTSFPHFLYQPSQFGFEATLYIPHAEFGEDIQDLYQEIEEMGDEQVDDFVEMEKEQHAFWKKKKKKKKKKTVQLASAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z843</accession>
    <name>W6Z843_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_110334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964234">
        <property type="protein sequence ID" value="EUC39866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693615.1">
        <property type="nucleotide sequence ID" value="XM_007695425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z843"/>
    <dbReference type="GeneID" id="19119583"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110334"/>
    <dbReference type="eggNOG" id="ENOG502R380">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038397_0_0_1"/>
    <dbReference type="OrthoDB" id="3719074at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="525" mass="60174" checksum="34F19CFC6F8AE84D" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8H6</accession>
    <name>W6Z8H6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pectate lyase</fullName>
            <ecNumber evidence="10">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_10041</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="10"/>
    <dbReference type="EMBL" id="KI964212">
        <property type="protein sequence ID" value="EUC39991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693489.1">
        <property type="nucleotide sequence ID" value="XM_007695299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z8H6"/>
    <dbReference type="STRING" id="930090.W6Z8H6"/>
    <dbReference type="GeneID" id="19117672"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10041"/>
    <dbReference type="eggNOG" id="ENOG502QU39">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044863_3_1_1"/>
    <dbReference type="OrthoDB" id="441042at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025095019" description="Pectate lyase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC39991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="256" mass="26468" checksum="13CF4244ACD254F1" modified="2014-04-16" version="1">MKASVAISILSFALAASAGPARIFPRNFYTMMKRGSLPVPQGNGTETFSKPKEITGVFDGGLKTYGRGVSCTGQVEGGNSDAVFLLKDGATLKNAIIGKDQIEGVHCEGSCTIENVWWVSVCEDALTLKGDGDATVIGGGATAAEDKVIQHNGKGTVTIENFTVDNFGKLYRACGNCKESAERHVVIKGVKATNGKLLAGINSNFGDSATIDAATCATGVKEICEEFKGTTPGNEPDAVSKGPSSACQFSGKIAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8V7</accession>
    <name>W6Z8V7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_99410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="Han J."/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
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            <end position="150"/>
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    </feature>
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            <end position="232"/>
        </location>
    </feature>
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        <location>
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            <end position="217"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC40296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="462" mass="50484" checksum="C3F692C829AA024E" modified="2014-04-16" version="1">METISYTFATKRDDAVAPANPILASSLIDDDELDDLIDRLYNSGIREAKQEKERIGIGIKSVDTALFGGLESGRVIEISGEASAGVREVYTALLVTCLLQNPKSTAAVVDTTGNFDVLRLYTHIIARLSCQTQDLLAALRESVGFGSDARAEDVAAKMLDRVKIMRVFDFEGVREAVGEIGDEVEGRGGVGEKDVGQKEEVLGEEQVRVDEANEPPKRTFVPDSEDEGEEEEEEMLFEIKDKHILAPRVQDTDAISAPELEKPGHADTEEQATQTKSKKSTPSTLKFILIDNLARVFGPLSKNDMNKATSLASTLLLTLTCLTRHHTLYTLLVTPTTPPPAPRAASPTRAVPSHRSHAPNHSGPDQPEPIPQPSIFLSNKVGPGIPGLTGLMGLYSDVRVLISRMPYRKVDARIYYDENIDKARKRRVEMVGVLEVVGDRWGGRTGSWGVFAKGQDGIVDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9K1</accession>
    <name>W6Z9K1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lytic polysaccharide monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_25375</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963963">
        <property type="protein sequence ID" value="EUC46665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686823.1">
        <property type="nucleotide sequence ID" value="XM_007688633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z9K1"/>
    <dbReference type="STRING" id="930090.W6Z9K1"/>
    <dbReference type="GeneID" id="19120749"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25375"/>
    <dbReference type="eggNOG" id="ENOG502RY3D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_1_3_1"/>
    <dbReference type="OrthoDB" id="4849160at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF34">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889828" evidence="5">
        <location>
            <begin position="17"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="6">
        <location>
            <begin position="15"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC46665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="250" mass="26757" checksum="413E7ED5344EB374" modified="2014-04-16" version="1">MLSLLVLLAPLVAAHGHVDKVLADGKEYQGWNAALKYQNPIPATVGWQADNLDNGFVSPDAFGTSAIVCHKQGKSNGAYVTVKPGSKVTFKWDTWPVSHVGPVQEYIAPCNGDCGSVDPSSLQWTKISSKAWKSGSNPGKWATDDLIANNFSWDITFPNVAPGNYVVRHEIIALHAAGQTNGAQSYPQCINFKVEGSGTAKLSGGTPATSFYTANDPGIKFNVFTSFSSYPVPGPAVKSLTKRHAKDLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z9S1</accession>
    <name>W6Z9S1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="3">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_9675</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="3"/>
    <dbReference type="EMBL" id="KI964164">
        <property type="protein sequence ID" value="EUC40451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693025.1">
        <property type="nucleotide sequence ID" value="XM_007694835.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6Z9S1"/>
    <dbReference type="GeneID" id="19128909"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9675"/>
    <dbReference type="eggNOG" id="KOG0902">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000893_1_0_1"/>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030866">
        <property type="term" value="P:cortical actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140504">
        <property type="term" value="P:microlipophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060237">
        <property type="term" value="P:regulation of fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05167">
        <property type="entry name" value="PI4Kc_III_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.70:FF:000011">
        <property type="entry name" value="Phosphatidylinositol 4-kinase alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000022">
        <property type="entry name" value="Phosphatidylinositol 4-kinase stt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000014">
        <property type="entry name" value="Phosphatidylinositol 4-kinase STT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045495">
        <property type="entry name" value="PI4K_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF15">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19274">
        <property type="entry name" value="PI4K_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="10">
        <location>
            <begin position="1369"/>
            <end position="1555"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="1657"/>
            <end position="1926"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="300"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1942" mass="217436" checksum="5816DBED5694C3A1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAI3</accession>
    <name>W6ZAI3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_2408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684687.1">
        <property type="nucleotide sequence ID" value="XM_007686497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAI3"/>
    <dbReference type="STRING" id="930090.W6ZAI3"/>
    <dbReference type="GeneID" id="19120536"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2408"/>
    <dbReference type="eggNOG" id="ENOG502SANZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059580_1_0_1"/>
    <dbReference type="OrthoDB" id="5345504at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046591">
        <property type="entry name" value="DUF6649"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20354">
        <property type="entry name" value="DUF6649"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="241" mass="26452" checksum="7F38EE203B628B90" modified="2014-04-16" version="1">MAQVVAHSSQARPASYAQQQNAPHGKKRPADGSLENEQRLSKRFDLLNLVDHNGTRLYIPVPGSSQGTTTTQSQSSPTPVADALAFASTRPRRNRKPRAHDTMDIEDTPHRVYISDLSAELSDIESDEENPIFLSDIEKHLSRIPAHVLRGPDPTPNPQNQMVLYNVPTSLTVPEAQDNVRKAIVETRQRIRDRQVNPVTEPPGVFVRGAETGGAESSMVVERSNDIPPADEVGGDAMDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAX4</accession>
    <name>W6ZAX4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_27051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964000">
        <property type="protein sequence ID" value="EUC44619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688823.1">
        <property type="nucleotide sequence ID" value="XM_007690633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAX4"/>
    <dbReference type="GeneID" id="19121053"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27051"/>
    <dbReference type="HOGENOM" id="CLU_1128895_0_0_1"/>
    <dbReference type="OrthoDB" id="3737134at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="246" mass="27636" checksum="1F7F9B15F27E6B22" modified="2014-04-16" version="1">MPHSYNALFESSMTTTASMLPSRSNATHIIVPKASCQTASRCPVDLVKSKHMEIVLDFKWLDHKCVESFLSIVSQPEKFHGFLIDEKNLREQRLADWIISSPEEENVVGLEEPPPYTNAKHKRSRGAHSHSYAENSYPPNRKTDVNDPSTLKNNVRCVVLNRFPAMVASFIDRFRSASPSSSSSIYPTPPPPKQQHLHSNPSANSVCPLQNVPSNMLKRNSPPFPTTYSIMQIPSVWQPTRNSSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB67</accession>
    <name>W6ZB67_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_33510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963935">
        <property type="protein sequence ID" value="EUC49037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684409.1">
        <property type="nucleotide sequence ID" value="XM_007686219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB67"/>
    <dbReference type="GeneID" id="19122342"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33510"/>
    <dbReference type="HOGENOM" id="CLU_2621665_0_0_1"/>
    <dbReference type="OrthoDB" id="10442401at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="78" mass="8624" checksum="CF68E11284E43725" modified="2014-04-16" version="1">MQTSLVVTRTPHCERIAQLGTAAPCVVRPFLAAFDPSPIVPILAAPRPQLPILYCTLLQFLLVWTLTTTPCWYPFLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBQ7</accession>
    <name>W6ZBQ7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Acireductone dioxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Acireductone dioxygenase (Fe(2+)-requiring)</fullName>
            <shortName evidence="15">ARD'</shortName>
            <shortName evidence="15">Fe-ARD</shortName>
            <ecNumber evidence="15">1.13.11.54</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Acireductone dioxygenase (Ni(2+)-requiring)</fullName>
            <shortName evidence="15">ARD</shortName>
            <shortName evidence="15">Ni-ARD</shortName>
            <ecNumber evidence="15">1.13.11.53</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ADI1</name>
        <name evidence="19" type="ORF">COCMIDRAFT_35234</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:49016"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.53"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16723"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="15">Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat striatin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the acireductone dioxygenase (ARD) family.</text>
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        <property type="reaction ID" value="UER00878"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase"/>
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        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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        <property type="entry name" value="WD_REPEATS_REGION"/>
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    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="135"/>
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            <begin position="332"/>
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        <location>
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        <location>
            <position position="831"/>
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        <ligand>
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        <ligand>
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            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29033"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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        <source>
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        <source>
            <dbReference type="EMBL" id="EUC47238.1"/>
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        <source>
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    <sequence length="925" mass="101789" checksum="54F40F87C629947E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBZ5</accession>
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        <recommendedName>
            <fullName evidence="11">Zinc/iron permease</fullName>
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        <name evidence="9" type="ORF">COCMIDRAFT_106677</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="46591" checksum="F3C379811BD5A41C" modified="2014-04-16" version="1">MWDGLFMLLALSTVMGIASFLAGILPLSFNLSTRQLRTMTLLGTGVLVGTSLIVIIPEGIETMYSAGMKTHAHSRSVRSVAQPAILSARSLQGDLLHAPEFPAWKRADQVDVKDIGGAIELQMSKAKYARQAEKPTEDPHPQKGGDDDSTEGHKEGHTRVHAPEDEEKPHGHAEAGHDDGSSPHAYIGVALILGYILMFLVEHLPEALASGQPEYQPMHISLSNLARGPHNSSSLSVNGMGMQSAAVTPLATPGLPPPPTKKTPAATIGLVVHACADGIALGASSTAESTSLSLVIFFAIMLHKAPAAFGLTSVLLKQGLSKRKARTHLAFFSLAAPVGALATWTIVHMFGRNHLGGDEGLTWATGWVLCFSGGTFLYVAMHSMADATASQHAHEDPTANGYMEAYSGSNRMSKTDVSIVMLGMLLPLITQIGHAHSHGH</sequence>
</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">ATCC 44560</strain>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZC81</accession>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
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    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
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        <text evidence="13">Subunit of dynactin, a multiprotein complex part of a tripartite complex with dynein and a adapter, such as BICDL1, BICD2 or HOOK3. The dynactin complex is built around ACTR1A/ACTB filament and consists of an actin-related filament composed of a shoulder domain, a pointed end and a barbed end. Its length is defined by its flexible shoulder domain. The soulder is composed of 2 DCTN1 subunits, 4 DCTN2 and 2 DCTN3. The 4 DCNT2 (via N-terminus) bind the ACTR1A filament and act as molecular rulers to determine the length. The pointed end is important for binding dynein-dynactin cargo adapters. Consists of 4 subunits: ACTR10, DCNT4, DCTN5 and DCTN6. The barbed end is composed of a CAPZA1:CAPZB heterodimers, which binds ACTR1A/ACTB filament and dynactin and stabilizes dynactin. Interacts with ATP7B, but not ATP7A, in a copper-dependent manner. Interacts with ANK2; this interaction is required for localization at costameres. Interacts with N4BP2L1.</text>
    </comment>
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        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
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        <subcellularLocation>
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            <location evidence="2">Stress fiber</location>
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        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the dynactin subunit 4 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001725">
        <property type="term" value="C:stress fiber"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="DCTN4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13034">
        <property type="entry name" value="DYNACTIN P62 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13034:SF2">
        <property type="entry name" value="DYNACTIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05502">
        <property type="entry name" value="Dynactin_p62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
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        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
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        </location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
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        </location>
    </feature>
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        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00004529"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC41341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="570" mass="63117" checksum="FF84723CD5616200" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCS0</accession>
    <name>W6ZCS0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Translocation protein sec66</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_89713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963950">
        <property type="protein sequence ID" value="EUC47613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685863.1">
        <property type="nucleotide sequence ID" value="XM_007687673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCS0"/>
    <dbReference type="STRING" id="930090.W6ZCS0"/>
    <dbReference type="GeneID" id="19127529"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89713"/>
    <dbReference type="eggNOG" id="KOG4699">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066294_0_0_1"/>
    <dbReference type="OrthoDB" id="73168at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031207">
        <property type="term" value="C:Sec62/Sec63 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018624">
        <property type="entry name" value="Sec66"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28229">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28229:SF1">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09802">
        <property type="entry name" value="Sec66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="24151" checksum="B5652AA68D5E19BD" modified="2014-04-16" version="1">MWPFDAVDWLMLTVPFAYIGILAGSFGVFTNLYRKRKAANAASLEPWFPTHLQRNVYLSLLHMEDPKVPDSILKAALLRRATEDIHRIVQIRNAKQALQVLLQRGSVGDDLWQRFQRAEKEIEEELRDVVNEANAFAPNWGQTIFQSASEMAQNNHIRERLAEIEAKAPAEKEWWENRRAGIQSEFMKELDDEKAKSEEDGVMVEKSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZCU8</accession>
    <name>W6ZCU8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_96098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963988">
        <property type="protein sequence ID" value="EUC45234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688257.1">
        <property type="nucleotide sequence ID" value="XM_007690067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZCU8"/>
    <dbReference type="GeneID" id="19128786"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96098"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_23_1"/>
    <dbReference type="OrthoDB" id="195446at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="229"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="453" mass="51618" checksum="90C76C764A02D581" modified="2014-04-16" version="1">MDTAASLIAIATLCEKLIKYINATRAAKDDRQRLRSQIRACSHIILQLKDEAEDSENIEESEEWAKSMQLLSSPLHRLHEALSVAAQALSPRDSTVEKLKWPFKEQDVRKLIDAVRCEMDLLSLALDRNSTRLLQKISLHSQHNEQLLMELKATMGTRDVGHQAALENVAEKLGRLEMGQNGVQGHVQQLHERHDLEEAIRKRQSILEWLTPIDYESQQREAIRSRQAGTGQWLLNSQQYQDWLAEKHPTLFCPGIPGAGKTVLASIINEDLRHRFYANPQVGFAHLFFDYRRQDQQSLEVLFSGLLKQLVAQQLPLPKQVEAFYTTHRQKYSGQVRTVVPTLEAVIASFSRVFIVLDAVDECLAPEQNCTDFLCVIQELQGRHKLQLLATSRVIPEVTERFTTASVLQIQADAQDVRKYLTQQVHRLPGFVRKDVELQNEVVSSIVEAVRGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZD93</accession>
    <name>W6ZD93_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_88580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963946">
        <property type="protein sequence ID" value="EUC47955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685513.1">
        <property type="nucleotide sequence ID" value="XM_007687323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZD93"/>
    <dbReference type="GeneID" id="19127305"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88580"/>
    <dbReference type="HOGENOM" id="CLU_956420_0_0_1"/>
    <dbReference type="OrthoDB" id="3692963at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="294" mass="33534" checksum="A900B5457371E02F" modified="2014-04-16" version="1">MNTHQWLIEHCPLGATGNEMDPVAGPTGNSDTQETPIWPQRLLVRVDSHHSTQDTPDSLHSSNESRESEEETAPSSTPATLDTQDHYELHPSIISSIEALLQDSDNDNEPVDLLTPSSPQSYPISLAEQQTMILHQDLISLFIHHRIAATTFSAPSPSALLATEEMETLMSHYETNLISPLYSGISTRIHTSILYTAYIISDRTFFPRSPFTSLAFSYLSPQRYLVSRLRYQRVSSEMLVVFQNSQTLMRELEAVMWGRRRYLRRLRRYPEVVARTIWMLDPTVTHRWVGPLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDQ0</accession>
    <name>W6ZDQ0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4238 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_49889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685336.1">
        <property type="nucleotide sequence ID" value="XM_007687146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZDQ0"/>
    <dbReference type="STRING" id="930090.W6ZDQ0"/>
    <dbReference type="GeneID" id="19124457"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_49889"/>
    <dbReference type="eggNOG" id="ENOG502S5TP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022619_0_0_1"/>
    <dbReference type="OrthoDB" id="5340163at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025332">
        <property type="entry name" value="DUF4238"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14022">
        <property type="entry name" value="DUF4238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="51281" checksum="726F92FE0FCF2357" modified="2014-04-16" version="1" fragment="single">MDFTQYQHYVPQFMLRRFAPTQPIGPSNVSASYRKSERQRRKNNASVKVPHLDSSPPIITDKPIRRTFGQQDMYNDGLKDSVETKLGEIERKAARIIARVVDAQEAGKEGISLLRSEKDLLRKFQFVMRYRSPIFFRRFNHQTAEGYDSDDRDTFLEYMRDNQFSRPLDVWVNNLEKIIDTPMDPAGHWAWELAGTIYPPDAHWLATNIRSMYMAFVTPSDPQEEFILTENAFSIHEGPVSYTVDRFTGEEKQTVYTEFHLLTVISPRLAIVFRSNDMPEPLEDLFPGFREQKLDMLAAIASVHTDPEHATSLLEDLPIAKARNSYTTVRNGRIELAEGADGEPRMNDKFDFIFFRLESNHAQKINMVMLDQAYKIDQLVFKSKSALRKALEFYLEYPCLTRGLYSMKTVSDKPDDPRLRFLKKMEHVAHTLGSSAVAKYHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50332.1"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="30040" checksum="38449525504A60AF" modified="2014-04-16" version="1">MVASTTVSFDDFVKQSREKKKNETLAQQFLGGGSRGRKPNASAAGAKPRVDSEKPSLLSRINGGAGVQKRSASAKPAGSIDGKWQHDLHKLNNPRGAANTRNHLARTASASQVERNTRTFDKFASSLNRGAGAHNNDGAGISIRGVANGGPCTVIASNFAPGTTAADIEAVMSPIGGETLGCKLLSASPTVMVELQFATREGAENVIATFNNQKADGRLLYVYMKDVPASTHMSLSRAPAGRLTQSADDMEIDTGARAGSFQDGRYGFNEGGHRDPPRGPRRRY</sequence>
</entry>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
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            <taxon>Pleosporineae</taxon>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">ATCC 44560</strain>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
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        <property type="entry name" value="BROMO"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="350"/>
            <end position="422"/>
        </location>
    </feature>
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        <location>
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    </feature>
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        <location>
            <begin position="751"/>
            <end position="833"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
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    </feature>
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        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC50382.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="908" mass="98690" checksum="3539B66410EE4C9E" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZF92</accession>
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            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
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                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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                <person name="Lindquist E."/>
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                <person name="Ciuffetti L.M."/>
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            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08192">
        <property type="entry name" value="MAR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF97">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE IRON-TYPE_GLYCEROL DEHYDROGENASE GLDA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="2">
        <location>
            <begin position="20"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="3">
        <location>
            <begin position="185"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC48675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="379" mass="40853" checksum="D2EC9FD79EE7D75F" modified="2014-04-16" version="1">MTEATNRPLSGLWQPTQLQRLYYGADSVTKYLLACLPKTSSKAFIITGTSLATKTPLVKQVEELLGEKHAGTFSKIGEHAPVAQLDEATKLVKKDETIDTVISIGGGSPIDSAKAISYRLHEKTGKFLYHITIPTTLGAAECTFIAGYTGVDGVKIGVRAKELVPSVVFYDSKFALYTPERLWMSTGIRAMDHAVELLYHPTASEMPARWLALQSAATLFEALPKYKQDPKDEDNITRLQLAAYGSLGFIGYNLVGGIGLSHALGYALGSPYGIPHGITSCLTLGHVVKLKAQDPAAAEQIARLRPFIGESASGDTQVDAEIVGDRVLKLVKDLGLDNDLRNYKVGRDQVPVIMERATGGMIDGAVYDAVEGLVKGLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFA4</accession>
    <name>W6ZFA4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_104283</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964071">
        <property type="protein sequence ID" value="EUC42161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691335.1">
        <property type="nucleotide sequence ID" value="XM_007693145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFA4"/>
    <dbReference type="STRING" id="930090.W6ZFA4"/>
    <dbReference type="GeneID" id="19118477"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104283"/>
    <dbReference type="eggNOG" id="KOG1414">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_924351_0_0_1"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="218"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC42161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="302" mass="33225" checksum="C4022851F3303065" modified="2014-04-16" version="1">MSTTVMFSHTNSFGEPDLYGRMSGLSPGYGSFFNNFNTTAATEPINYNSHAPQHQNPGQAPIHGWSSSSLSILQPQSTQHTLASQPHTSTDPASTASINPVALSTPTFTPANRPTGYYDSTSTISSSQSNFDTSNSASPVSFTVPSRRDSLYLKESSSLYSQDEETPSRRPSTTTTATTAASPPSTTTTTTTTTTTTGRRRRSSEYVEPGSARAIYLEKNRRAASKCRSKQKHEQEQLVERSRQYERKNRMLKAEVDMLQSEVRALKDLLGQHAHCPDQRIAQYLQLEASRLASSRNYSASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFE0</accession>
    <name>W6ZFE0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">D-2-hydroxyglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="11">1.1.99.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_93512</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate. Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC). Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>(R)-malate + A = oxaloacetate + AH2</text>
            <dbReference type="Rhea" id="RHEA:67460"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15588"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:67461"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.39" evidence="11"/>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687314.1">
        <property type="nucleotide sequence ID" value="XM_007689124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFE0"/>
    <dbReference type="STRING" id="930090.W6ZFE0"/>
    <dbReference type="GeneID" id="19128282"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_93512"/>
    <dbReference type="eggNOG" id="KOG1232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_4_1_1"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051990">
        <property type="term" value="F:(R)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2190:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000053">
        <property type="entry name" value="D-lactate dehydrogenase (Cytochrome), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="17">
        <location>
            <begin position="125"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00039639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EUC46209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="557" mass="61530" checksum="3226A9FB21A8FEA1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFM4</accession>
    <name>W6ZFM4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydroorotate dehydrogenase (quinone), mitochondrial</fullName>
            <ecNumber evidence="5">1.3.5.2</ecNumber>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Dihydroorotate oxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">E3 ubiquitin-protein ligase CHIP</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">RING-type E3 ubiquitin transferase CHIP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">COCMIDRAFT_33948</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(S)-dihydroorotate + a quinone = orotate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="5"/>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="KI963939">
        <property type="protein sequence ID" value="EUC48673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684842.1">
        <property type="nucleotide sequence ID" value="XM_007686652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFM4"/>
    <dbReference type="STRING" id="930090.W6ZFM4"/>
    <dbReference type="GeneID" id="19122445"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33948"/>
    <dbReference type="eggNOG" id="KOG1436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4642">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_375047_0_0_1"/>
    <dbReference type="OrthoDB" id="14784at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106430">
        <property type="term" value="F:dihydroorotate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16654">
        <property type="entry name" value="RING-Ubox_CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000242">
        <property type="entry name" value="Dihydroorotate reductase PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045202">
        <property type="entry name" value="CHIP_RING-Ubox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF4">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0288">FMN</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="U-box" evidence="18">
        <location>
            <begin position="214"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="706"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00017599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EUC48673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="840" mass="92039" checksum="37807D9ABCFC1CF0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFR6</accession>
    <name>W6ZFR6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_93041</name>
    </gene>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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                <person name="Wang R."/>
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                <person name="Han J."/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC49110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="655" mass="71554" checksum="368FF75668973320" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZGM5</accession>
    <name>W6ZGM5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_7823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dothideomycetes</taxon>
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            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964054">
        <property type="protein sequence ID" value="EUC42651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690830.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZGM5"/>
    <dbReference type="GeneID" id="19125403"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7823"/>
    <dbReference type="HOGENOM" id="CLU_849890_0_0_1"/>
    <dbReference type="OrthoDB" id="3693998at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC42651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="327" mass="35988" checksum="165832B8AF83F588" modified="2014-04-16" version="1">MSKVGLMTRRLPIKNAHKAAKTAVTAAGVVLAGPIVSFLPLGPFTAILSLLATSLASSHLKHKIIGGVIAFLYAGGLHGFEGQLLALLSYFSFTSAFDKLSGNIHAMYKESAFTIGFSRPESTQLFLFVLSELLELPWAIPVVVRAVVNNVSQLASQSYATISSTKPSFDTSKPPLRLLIQTLSNLYTMDKYADDDVESLNASQDIQNGIPSSITPSLPPEIPSYESSPEEWSEEREVVEDTCDDELWKGGSLNDEERRTQALFDELNHLIDECDGLNSAQWNEVIELLNEKEGFEIDRGECMVSAHFEDWAQRDAEIELSVLYPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZH70</accession>
    <name>W6ZH70_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_1830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684048.1">
        <property type="nucleotide sequence ID" value="XM_007685858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZH70"/>
    <dbReference type="GeneID" id="19119955"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1830"/>
    <dbReference type="eggNOG" id="ENOG502SHIH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012049_0_0_1"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="598"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="598"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC49370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="679" mass="75988" checksum="1A306B9B4124E0E8" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHD4</accession>
    <name>W6ZHD4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_39007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964043">
        <property type="protein sequence ID" value="EUC42961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690496.1">
        <property type="nucleotide sequence ID" value="XM_007692306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHD4"/>
    <dbReference type="GeneID" id="19123593"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39007"/>
    <dbReference type="HOGENOM" id="CLU_857870_0_0_1"/>
    <dbReference type="OrthoDB" id="3690638at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="35757" checksum="E2641B036CB19B60" modified="2014-04-16" version="1">MHVNTHISLGAPFLSFSTLDHRIEQDPDLFFPSEAFQFSPDEPLYDSVSLVDGQIPGYSGSNNACSQSGLLEQTDYLGNTIYGSYKSVNTTQTLGTLDESVHQGTSGAGYSSTSGCIDPSVLTQHVHEPHSCSRPWLDQHTNQTLAENSQSQLSPQQPRPTQGTNARAPTMPNDMSIEAYPSPSSLPSLGQLTPQVASPSATTQIELDIPDGKVAIKPVGMRFTCKTCRKSIPNRRANLHNCKAPSRCEKCGRSIKLAKDLKRHMGLNNASPSCPALKNDSLWASSFMCLCRSKPYARKDIFVRHLRTSKAENHRCRTCNKNPCACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHQ9</accession>
    <name>W6ZHQ9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_84515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963931">
        <property type="protein sequence ID" value="EUC49525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684031.1">
        <property type="nucleotide sequence ID" value="XM_007685841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHQ9"/>
    <dbReference type="GeneID" id="19126479"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84515"/>
    <dbReference type="HOGENOM" id="CLU_2326263_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC49525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="99" mass="10771" checksum="A1D14C2F3DFF5B52" modified="2014-04-16" version="1" fragment="single">YWLVCDGRLCSPGSPGRGFCIPRRRCRPNTSPVHPLAILVRMPVISLANMDVFVLAVSCEPISRCGDISVQSSKLVEQIHDQTIVMSFPTLGVVPHPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZII0</accession>
    <name>W6ZII0_COCMI</name>
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        <recommendedName>
            <fullName evidence="4">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_28145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964031">
        <property type="protein sequence ID" value="EUC43361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690101.1">
        <property type="nucleotide sequence ID" value="XM_007691911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZII0"/>
    <dbReference type="STRING" id="930090.W6ZII0"/>
    <dbReference type="GeneID" id="19121253"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28145"/>
    <dbReference type="eggNOG" id="KOG2595">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039465_0_1_1"/>
    <dbReference type="OrthoDB" id="206700at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000060">
        <property type="entry name" value="TBC domain protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1310:FF:000001">
        <property type="entry name" value="TBC1 domain family, member 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045913">
        <property type="entry name" value="TBC20/Gyp8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913:SF7">
        <property type="entry name" value="RE60063P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 20/GTPASE"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
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        <location>
            <begin position="65"/>
            <end position="248"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC43361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="421" mass="47600" checksum="7034DE2C321AEA32" modified="2014-04-16" version="1">MASPTSSASLSRSVSASSTSLPSRHSTPVATLSPAEQEKEALVRAAIDNDDVAALVHLATTSHGLVSDSLRRTAWPLLLGCSESDIAKEPHAALPEHEDEHQVGLDVNRAFVYYPKNESENKLQQRKKDLSYVILDVLRRHPSLSYFQGYHDIVQVFLLVLGPEHAPAAVARLSLLRIRDFMLSSLEPALAQLELLRPILRAADPVLYDHLPKSQPSFALAGTITMFAHNIQDYKDITRLFDFFLARHAVMPIYLFAAVVLSKRDELLEIDQDDEDILYVMLGRLPQPFDVEFHIARTVELYERLPPARLNSWEWWRISSSSVLKSSATSDSLRRLTLEDGEMFLAQQERDLRRQQVLRRAAKNVEYLRLRLWFYRRYGAVSLAVLVGVYAVWLGRNGDVSTRYPLLGPLGQFLSKYLGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJB9</accession>
    <name>W6ZJB9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_89748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685955.1">
        <property type="nucleotide sequence ID" value="XM_007687765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJB9"/>
    <dbReference type="GeneID" id="19127541"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_89748"/>
    <dbReference type="HOGENOM" id="CLU_1844749_0_0_1"/>
    <dbReference type="OrthoDB" id="10565675at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887129" description="REJ domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="14774" checksum="E5D91F475E196886" modified="2014-04-16" version="1" fragment="single">TWNCDTSSTVMSVNCLVVSCSVLPLLWCASSKPTYTCSTSLPLSSMSSSVLPPVEKFAVCSALMITSSLSSTTCLSLTISPISSVSSTESLPFMVLLPSLRRSVKVSTSSWMVTSLLRICVSVRNLFSSELLKRVMST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZK46</accession>
    <name>W6ZK46_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7357 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_24368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963948">
        <property type="protein sequence ID" value="EUC47814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685666.1">
        <property type="nucleotide sequence ID" value="XM_007687476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZK46"/>
    <dbReference type="STRING" id="930090.W6ZK46"/>
    <dbReference type="GeneID" id="19120580"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24368"/>
    <dbReference type="eggNOG" id="ENOG502SF1H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002397_1_0_1"/>
    <dbReference type="OrthoDB" id="5368821at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055781">
        <property type="entry name" value="DUF7357"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24054">
        <property type="entry name" value="DUF7357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7357" evidence="2">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="697" mass="76015" checksum="AAA068EDB292FED6" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKY8</accession>
    <name>W6ZKY8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_21733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963921">
        <property type="protein sequence ID" value="EUC50715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682659.1">
        <property type="nucleotide sequence ID" value="XM_007684469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKY8"/>
    <dbReference type="GeneID" id="19120113"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21733"/>
    <dbReference type="HOGENOM" id="CLU_1288700_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="214" mass="24064" checksum="C54F1F6B6BC015AA" modified="2014-04-16" version="1">MAVSIRGRWIRYASIYDGGCDSGARERSSAWVAAQVCLDEFTNVEVLHVSPRRCMRVPRPDKLTRRFGSDETQGPRAHHLNRQSRRPSSASGAYSTVSTEKRPRRGLAMMPRDFLPNTPRLGGHACPMVIPTHLLTYLLTHEHFGLSDMGLTFKGPFLASSLPLICFFRLQIASSWDPNPHHANGRSQECLPNTVLCHYSRRAPAPQEIRFAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLE4</accession>
    <name>W6ZLE4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">NAD(P)H-hydrate epimerase</fullName>
            <ecNumber evidence="3 10">5.1.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">NAD(P)HX epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_2795</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="10">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.6" evidence="3 10"/>
    <dbReference type="EMBL" id="KI963942">
        <property type="protein sequence ID" value="EUC48354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685111.1">
        <property type="nucleotide sequence ID" value="XM_007686921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLE4"/>
    <dbReference type="STRING" id="930090.W6ZLE4"/>
    <dbReference type="GeneID" id="19121214"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_2795"/>
    <dbReference type="eggNOG" id="KOG2585">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024853_3_0_1"/>
    <dbReference type="OrthoDB" id="10064708at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NAD(P)HX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10260:FF:000005">
        <property type="entry name" value="NAD(P)H-hydrate epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032976">
        <property type="entry name" value="YJEFN_prot_NAXE-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232:SF10">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="11">
        <location>
            <begin position="11"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="61"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="127"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC48354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="236" mass="25644" checksum="7255655795BA3200" modified="2014-04-16" version="1">MAIRTLSAKSAAALDQELMSTGAFSIDQLMELAGLSVSQAVFKLQPLSKGKRILVACGPGNNGGDGLVAARHLFHYGYQPTIYYPKQSKNELYQRLKKQLEDLKVPFTEDFAGALNQTDHIVDAIFGFSFSGEVREPFPKVIEALASTSVPVLSVDAPSSWDIEEGPRDSGPGKGFMPPALISLTAPKPLIKKFSGRHFLGGRFLSPEMAEKYNLDIPKYEGLDQVVEMPVDGGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZLZ8</accession>
    <name>W6ZLZ8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_37595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688886.1">
        <property type="nucleotide sequence ID" value="XM_007690696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZLZ8"/>
    <dbReference type="STRING" id="930090.W6ZLZ8"/>
    <dbReference type="GeneID" id="19123280"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37595"/>
    <dbReference type="eggNOG" id="ENOG502SJHU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_665628_0_0_1"/>
    <dbReference type="OrthoDB" id="3674542at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="46774" checksum="7AA3C4AAA00CEAE9" modified="2014-04-16" version="1">MLSRDQRLSKRMQEADPALKEVDMDMLSYARKLFYFRHLANGGIGLGSVFVHTSEDAPGFLEAVVMARDFKSTDPRDKIFALWNLAQDKTGIDFKPHYTEPYERIYADFARAWINQKHSLDILGAVEASESSSSFYRKTPSWAPDWSVPTQTSCLVRKDYIPMKFISVVDDQQGKLYAADGGITRDTFEDTLLHFQDNVLHCTGLIIDQVGAILQQPPQISSETVHLQSGDPDWEFHCWTIELTQHFRNFGSSIYDDPLRAAWAMCHGDNTAAWPPNPDFKSPLDDPYTCQTELSKHVSAWVHGYRESEARNIVRQVLRGRRAFISEAGYMGLMPAYIADKWSEIGEMCHLAVIAGCSIPLVLRERDNETYTVLGACFVQGWMEGEWIETMMGAGSPTEFWTGMRGVAALRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMI3</accession>
    <name>W6ZMI3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_31742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963919">
        <property type="protein sequence ID" value="EUC51183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682381.1">
        <property type="nucleotide sequence ID" value="XM_007684191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMI3"/>
    <dbReference type="STRING" id="930090.W6ZMI3"/>
    <dbReference type="GeneID" id="19121946"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_31742"/>
    <dbReference type="eggNOG" id="ENOG502QQZ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048901_0_0_1"/>
    <dbReference type="OrthoDB" id="342264at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00027">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561">
        <property type="entry name" value="DNA REPLICATION REGULATOR DPB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 2-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC51183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="452" mass="50106" checksum="8FF7D8079A928C67" modified="2014-04-16" version="1">MGILKNLVIATTGTHTYPPKQIQGWIERNGGRYSPTVHEGVTHLLASEEAYKSKQRTEAVRQALSLCIQILSYDWLDDSLNARRKLPVKSYAREVLSDKRRMAKKLKRLGAEADGKKFREGCEEIKKLTGSEAELKDPSHPTPSPTLSIKSAQAPSSTPDDSRTQAKSHWKAEYHYYQDTTGFDYKITLVQTNVSNTVTAKYHIGLLESHTKPHTYWGLAQYQHLSTTTTTNSTSSPANPDPANPQKAHVESEKSRLLSLICPPPHIHPLCPRNSPFTTAWRSFRHAFHDLCLIPWESRFDAHATSLQKREAARLNAEPYRYVRPRLGMPVGVFPQAAGLFANAKSGSVGAGGGSEDAEYVRGQVGIPLFEGLDEKGLFGAVVVREREGERVRVEEERRKNGEIGVGVGGEVLEGKKKRRRREGGRLGDGVDGRGFVAPEFAHLLRGVGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMV8</accession>
    <name>W6ZMV8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_37255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688530.1">
        <property type="nucleotide sequence ID" value="XM_007690340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMV8"/>
    <dbReference type="STRING" id="930090.W6ZMV8"/>
    <dbReference type="GeneID" id="19123209"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37255"/>
    <dbReference type="eggNOG" id="ENOG502SVHP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036917_0_0_1"/>
    <dbReference type="OrthoDB" id="5431013at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF4">
        <property type="entry name" value="FUNGAL N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="436"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="149"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC44921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="54826" checksum="7AA5AD7FD9342CAD" modified="2014-04-16" version="1">MAEAIGLVASVLQLAGTGLKLSQALYQYADSVATADRRIRDVAKEIKLTSFVIEELGGIFKQDDTLSLISKSAIATANETLNECSTMFGEIEATLNKSKKGKMGRLMLPFREPKIELLRSHIDKLKSTLQLLMQVLMHAFHVSSKKLDREAEARQREEIRQLLENKKNTTKRYEESLQRFKTSDSNTELEDDEISFDDNGSVSTLVAKSIGSTMTSDSLAECAQHVRTLLENIERLQQALANASEGDDQSDDHQMVIGSYFAARSHLDTILLGSSSTRSKTVMLKAENHINEEALFRTSKPKTISVGKEKKESIIAIETGAEEKVEERVKQEKIPMRLQGTKRPNEGIAYVQRPKSSRQHISDTLFGSSKPHAGGDDQLRYGTSPFSCLSDHQGRIQTFGSASAWEYSYHYSMSPNPPEKEEICVSVPRSPAYAPALSSPAYSPASPPHSSPVPSPAYAPALSSPAQVEFAKPSSESVSEGDDEVDELLKEWTTCFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN58</accession>
    <name>W6ZN58_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC45016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688486.1">
        <property type="nucleotide sequence ID" value="XM_007690296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN58"/>
    <dbReference type="GeneID" id="19123206"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37247"/>
    <dbReference type="HOGENOM" id="CLU_2120675_0_0_1"/>
    <dbReference type="OrthoDB" id="10343621at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687675.1">
        <property type="nucleotide sequence ID" value="XM_007689485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQ43"/>
    <dbReference type="STRING" id="930090.W6ZQ43"/>
    <dbReference type="GeneID" id="19128454"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_94464"/>
    <dbReference type="eggNOG" id="KOG3043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_2_3_1"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF105">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G08790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="296" mass="32317" checksum="55CEACCEB1123C4E" modified="2014-04-16" version="1">MSCPDCFRGSSHANLGQSTGKGQVLGVHGLTCYVALPPTPIANKPESTIIYLPDAFGWQFINNQLLADAYAKETGFRVIIPDIINGGPLNPIAMQLMDAVSEPVKGFNIWGYFRKGSAFVRLLTIVLPFMMRSSAYKTYPKLLEFARRVKAELPDGAKLGVCGFCWGGLPSTLLCTEPLATWSQDRLIDAHFAAHPSRLSVPKMVVDAIEKFKVPYSLAAASEDPILTPDKIENLSSTLKSSFGPGDGGNEFNYEIVVYPGSQHGFAIRAKEGDEDAAVSAKEAQAQAVRWFQRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSM1</accession>
    <name>W6ZSM1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_22112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683004.1">
        <property type="nucleotide sequence ID" value="XM_007684814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSM1"/>
    <dbReference type="GeneID" id="19120185"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22112"/>
    <dbReference type="eggNOG" id="ENOG502S3TJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066055_2_1_1"/>
    <dbReference type="OrthoDB" id="3915838at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887687" evidence="1">
        <location>
            <begin position="18"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="164" mass="17426" checksum="51DB94C7378D9B59" modified="2014-04-16" version="1">MLTFFAPLLLLAQSAAAAPVEDVVRAAATVGKIRGVRDPIYHLYLQASPKNSSKPVLGPESAAEEFTIGGTIQSKKTNQFLNIATASTSYKPLVWGAKGDTTAWGLEGDTIITTQGSSYGRQLNFLVCNSADAGYYDLFLQTGSDAPSGKTCSNYQTIHLPCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSV0</accession>
    <name>W6ZSV0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Epoxide hydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_4273</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963962">
        <property type="protein sequence ID" value="EUC46736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686755.1">
        <property type="nucleotide sequence ID" value="XM_007688565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSV0"/>
    <dbReference type="STRING" id="930090.W6ZSV0"/>
    <dbReference type="GeneID" id="19124187"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4273"/>
    <dbReference type="eggNOG" id="KOG2565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_0_1"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF39">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="4">
        <location>
            <begin position="10"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC46736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="379" mass="43311" checksum="8944565CB811B44E" modified="2014-04-16" version="1">MSYSPPDSAKPFTLNISDQDLSEWRQLLQLSKLPPDTWEGWQEDGSVGLPRKWLSEAKDYWLNKYDWRAAEKHINSFPNYKMQIEDVDLHFIALFSEKKDAIPLILMHGWPGSFVEFLSILSIVKKKYSTKDLPYHIVVPSLPGYTLSTIKGHDKHWDGENCGRVMNQLMLNLGFDKYLAQGGDVGHHTARLMARDYEACVGIHLNMIVTHPDEKTVVDEVEKQTLARAQKWGATGMGYAIEHGTRPSTIGSVLASSPLAMLAWIGEKMVEWSDEDPSLDEILTNVSLYWFTSSFPSSLWYYFEFFGGSPIPKLDFTKKPLGYSFFPYELSVGVKSILEKETNLVFYQRHERGGHFAALERPADLWEDIEGFVSKAWKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSY9</accession>
    <name>W6ZSY9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_25273</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the GSE complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963961">
        <property type="protein sequence ID" value="EUC46801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686699.1">
        <property type="nucleotide sequence ID" value="XM_007688509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSY9"/>
    <dbReference type="STRING" id="930090.W6ZSY9"/>
    <dbReference type="GeneID" id="19120736"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25273"/>
    <dbReference type="eggNOG" id="KOG3886">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044099_0_0_1"/>
    <dbReference type="OrthoDB" id="10020193at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd11384">
        <property type="entry name" value="RagA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.190:FF:000007">
        <property type="entry name" value="GTP-binding protein GTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000488">
        <property type="entry name" value="Small monomeric GTPase (Gtr1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039397">
        <property type="entry name" value="RagA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF1">
        <property type="entry name" value="RAS-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC46801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="353" mass="39848" checksum="42A2307DEEAEE5D8" modified="2014-04-16" version="1">MNSVKRQKQRKVLLMGKSGAGKSSMRSIVFSNYVAKDVRRLGATIDVEHSNIKFMGNLMLNLWDCGGQDGFVENYLNQSRNHVFGSVAVLIFVFDIESREFAADVVSYSNIIRALHECSPSAKVFCLIHKMDLVQARLRQAMFDERAEYIREASEGFKDTVEFFATSIWDQSLYKAWTKIIYYLIPNAGTIEALLEQLAEVIDARELILYERTTCLTVAHVTRQTEESNPFTDRFERISSILKTHKQSMAKHTNIPAGSANFAEMQIKTGRFMFFITRLTENTNLAVAIPPSEQVFNAARVNIFQVRPKFAELDIAAKPRPPIQQAFAGSADTMGDASERNKGRETAMHGSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZT19</accession>
    <name>W6ZT19_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_25193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963960">
        <property type="protein sequence ID" value="EUC46851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686623.1">
        <property type="nucleotide sequence ID" value="XM_007688433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZT19"/>
    <dbReference type="STRING" id="930090.W6ZT19"/>
    <dbReference type="GeneID" id="19120720"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25193"/>
    <dbReference type="eggNOG" id="ENOG502RBAK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013400_1_0_1"/>
    <dbReference type="OrthoDB" id="7295497at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="588"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="637"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="547"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="358"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="452"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC46851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="717" mass="79502" checksum="838D8E4A8DB6E3A1" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUR7</accession>
    <name>W6ZUR7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein with SprT-like domain at the N terminus</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">COCMIDRAFT_3517</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Spartan family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963951">
        <property type="protein sequence ID" value="EUC47571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685906.1">
        <property type="nucleotide sequence ID" value="XM_007687716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUR7"/>
    <dbReference type="STRING" id="930090.W6ZUR7"/>
    <dbReference type="GeneID" id="19122722"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_3517"/>
    <dbReference type="eggNOG" id="KOG3931">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019426_0_0_1"/>
    <dbReference type="OrthoDB" id="5236983at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044245">
        <property type="entry name" value="Spartan"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055220">
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Schackwitz W."/>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
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                <person name="MohdZainudin N."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Han J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="4">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC49306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="328" mass="36982" checksum="48FCB4BC484A534F" modified="2014-04-16" version="1">MAPANQKTYKFYNGVTIPAVGFGTFASEGASGETYAAVTTALKTGYRHLDCAWFYQNEEEVGAAVRDFLKENPSVTRKDLFICTKVWNHLHEPDQVKWSFNSSLTKLGMDYIDAFLVHWPIAAESDDNHMPKLGPDGRYIIKKDLTENPEPTWRAMEELYESGKAKSIGVSNWTIDGLKKLLSFAKVKPMMNQIEIHPFLPNTDLVKFCQDNDILVSAYSPLGSQNQVPSTGEKVRTNAKLNEVAQRSGYDLAQVLLAWGLQRGYVVLPKSSTPSRIESNWNIPELSKEDFEAVEEVARGRHTRFVNMKDTFGYDVWPEETDGGELKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W7A0V4</accession>
    <name>W7A0V4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UNC-50 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_22656</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-50 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683733.1">
        <property type="nucleotide sequence ID" value="XM_007685543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A0V4"/>
    <dbReference type="STRING" id="930090.W7A0V4"/>
    <dbReference type="GeneID" id="19120293"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22656"/>
    <dbReference type="eggNOG" id="KOG3012">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066239_1_2_1"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007881">
        <property type="entry name" value="UNC-50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12841">
        <property type="entry name" value="PROTEIN UNC-50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12841:SF6">
        <property type="entry name" value="PROTEIN UNC-50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05216">
        <property type="entry name" value="UNC-50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC49671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="28992" checksum="80C3458433AFEB01" modified="2014-04-16" version="1">MPRFFKRMFKFPQMDFEMAAWEIMSLIIAPKKVFRQIFYHKQTTKTYHRPDPSFTYLLSFFLTLTSLAWGFAYADGFTQTLHIMLVFIFGHFLLLSVVVATLFFFLVGRLLGPDNTLLPGRRRGLYNLGEDSGKEELEFGYCWDVAIRAFVPVWAFLYVVQFICMPLVGTQHWFSLLLSNTLYLLALNYYFIITFLGYKELPFLHHTELLLVPVAVMAILWFASLFGFNMSTHFAPVLWTGAKLRKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W7A3U6</accession>
    <name>W7A3U6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_81305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682944.1">
        <property type="nucleotide sequence ID" value="XM_007684754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W7A3U6"/>
    <dbReference type="STRING" id="930090.W7A3U6"/>
    <dbReference type="GeneID" id="19125846"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81305"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_1_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000049">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC50676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="488" mass="52620" checksum="910AD42827582785" modified="2014-04-16" version="1">MALQYSPKSLPKQIFINNEYVNSKSAKKLTLHNPKNGELIANNVPLAGEEDVDAAVDAAEKAFPAWKKMSATQRRGILNKFAELIEKNANEIAQLTRISLGSPAAFGAFEIGLCAETFRYNAGFIDKFGGESWPQEDGFLKIVRNEPLGVVAGIVPWNGPIGTIGLKAAPALATGNCFILKPSEKTPFSSLALGTLIKEAGFPPGVFQILSGDGSTGALIASHMRIRKVSFTGSIATGKKIQEMAAKSNLKRVTLELGGKSPAVVFDDCNLENAVKWTADAITANTGQVCFAASRVYVQEGIYDAFIEKYKAAMKDKVKEIGDPDKTSTNIGPLVDEAQFKRVQGFIERGQEKGYGTLAVGGNRVGNSGYYIEPTVFTDIDEKSELHCEEIFGPVSVVKSFKTEEEVMALSNNTNFGLMAGVFTTDINRALRVASEFDSGMVGINCVSLMFMNTPFGGSKESGLGRECGIHALRAFTEPKTIMINMNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W7A4G0</accession>
    <name>W7A4G0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_21421</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat ELP2 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Elongator acetyltransferase complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037289">
        <property type="entry name" value="Elp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
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    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
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        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
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        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
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    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="54"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="103"/>
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        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="201"/>
            <end position="248"/>
        </location>
    </feature>
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        <location>
            <begin position="393"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="615"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="663"/>
            <end position="706"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC51021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="806" mass="88124" checksum="70792340492F925A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6YLP8</accession>
    <name>W6YLP8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_60758</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_007695157.1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_60758"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC40137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="93" mass="10260" checksum="B95767E89E782D1A" modified="2014-04-16" version="1" fragment="single">QQNLRSINAPSDSYQCKNGATPSLECVDPLARPTCSCSCTNGVIFNQILPMSPQKDTNCDSCELEKKKCFDREQECRAEIVSVVKDQEDAKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>W6YN47</accession>
    <name>W6YN47_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_108082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="KI964144">
        <property type="protein sequence ID" value="EUC40712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692766.1">
        <property type="nucleotide sequence ID" value="XM_007694576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YN47"/>
    <dbReference type="STRING" id="930090.W6YN47"/>
    <dbReference type="GeneID" id="19119182"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_108082"/>
    <dbReference type="eggNOG" id="KOG0903">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002446_2_0_1"/>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140504">
        <property type="term" value="P:microlipophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000786">
        <property type="term" value="P:positive regulation of autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042998">
        <property type="term" value="P:positive regulation of Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050714">
        <property type="term" value="P:positive regulation of protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05168">
        <property type="entry name" value="PI4Kc_III_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000016">
        <property type="entry name" value="PIK1p Phosphatidylinositol 4-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021601">
        <property type="entry name" value="Phosphatidylino_kinase_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057754">
        <property type="entry name" value="PI4-kinase_beta/PIK1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049160">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21245">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11522">
        <property type="entry name" value="Pik1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="7">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="6">
        <location>
            <begin position="697"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="189"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="544"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC40712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="991" mass="108986" checksum="01DE4A716344EE7A" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPR7</accession>
    <name>W6YPR7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_110964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964292">
        <property type="protein sequence ID" value="EUC39645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007695643.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6YPR7"/>
    <dbReference type="GeneID" id="19119693"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110964"/>
    <dbReference type="eggNOG" id="ENOG502SQVI">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057752_6_1_1"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="8"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC39645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="220" mass="25157" checksum="81A51D020D263AAD" modified="2014-04-16" version="1">MRDDGEFADLVLTHNAGSFHAHRIIVCPQSKVFYKACTGGFKEFTGTIQMDHVQYIELKKLVDFFYSSEYDNCLPEEADISLLQLHARMFALADQYDIPGLTHLAAGKYFSRCTTSWEPLEFLVSLQDVYETSPASTRLLRDTACTAIRKHLPRMLNSEGVAEMYDKVLSEIPDFTKDLLRCYVSNPLYGHCQSCFTYQPMEALQGRCKKCKKGNRSFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YPW2</accession>
    <name>W6YPW2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_78258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964103">
        <property type="protein sequence ID" value="EUC41422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692053.1">
        <property type="nucleotide sequence ID" value="XM_007693863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YPW2"/>
    <dbReference type="GeneID" id="19125405"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_78258"/>
    <dbReference type="HOGENOM" id="CLU_2580184_0_0_1"/>
    <dbReference type="OrthoDB" id="9970474at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40518">
        <property type="entry name" value="ACETOACETATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40518:SF1">
        <property type="entry name" value="ACETOACETATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC41422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="81" mass="8935" checksum="02F636F9E0843503" modified="2014-04-16" version="1" fragment="single">MATYGTFGGDAGRHPVPRSEAPWEKLKAESYSLFLKLSDLPKGTYDEFEASWADKENGEFKGGLGAVIIVRYTETPVGMFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR69</accession>
    <name>W6YR69_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Branched-chain-amino-acid aminotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_104809</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964079">
        <property type="protein sequence ID" value="EUC41952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691534.1">
        <property type="nucleotide sequence ID" value="XM_007693344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR69"/>
    <dbReference type="STRING" id="930090.W6YR69"/>
    <dbReference type="GeneID" id="19118577"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_104809"/>
    <dbReference type="eggNOG" id="KOG0975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031922_1_0_1"/>
    <dbReference type="OrthoDB" id="409992at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009081">
        <property type="term" value="P:branched-chain amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000010">
        <property type="entry name" value="Branched-chain amino acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009897">
        <property type="entry name" value="PRK13357.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42825">
        <property type="entry name" value="AMINO ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42825:SF2">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC41952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="373" mass="40755" checksum="8EDE7A9B486729EE" modified="2014-04-16" version="1">MSDFPPPPVDTIDWSNVGFKIREVAGHVESHYSVETGKWTPPVFVEDPYLRIHGMAPGLNYGMQCYEGMKAFRAPNNTINIFRPNKNAERMQHSASFISIPEVPTEHFLACCSLAVGMNAAYVPPHETGAAMYIRPLLFGSSAQLGLNPPQEYTFVVYCIPTGVYHGSNPVDAVILEDFDRAAPEGTGSAKVGGNYAPVLRHSEKAYKAGYGITLHLDSKTRSVVDEFSTSAFIGVKKDGDKVKLVASNSKNVIQSVTGDSVLRIAESFGWEVESREIAYDEISTFDEVLAAGTAAALVPIKSITMQSKGDKFTYAEAQQEPGPVCKKLLTTLKGIQQGKIEDNKNWLYKVERPEQFGKQDQANGAKVVGQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6YR76</accession>
    <name>W6YR76_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_41585</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964209">
        <property type="protein sequence ID" value="EUC40013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693471.1">
        <property type="nucleotide sequence ID" value="XM_007695281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YR76"/>
    <dbReference type="STRING" id="930090.W6YR76"/>
    <dbReference type="GeneID" id="19124090"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_41585"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF162">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC40013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="56636" checksum="36A08572B6C58C2C" modified="2014-04-16" version="1">MAVSSLLREFSIPQQVGTVAVISFFILLSIVAYGCYLHPLSHVPGPFVAKFSPIWGMRALYRMKFNSELQALHEKYGPVVRVAPNEVSFATIEAETAIYANQEDSRFSKAGTFLTLFSDLVLNAPTLITIPDPALHKRLHRVIQQAFTPQALASQEPIQKLHIEKAIPDFDESAEEGRSMDLADKLETMFWEVIGDLAFGEPLMAGKRPTYETLKQLGKGSMPMVEALSFMLVMPGVAPALEMARGFLSAMPMSSQLSKLVPSKKLRDCVDRKDGREDFLSAIMGSEKQGLTLDADAFFSNAMGLTLAGYQTTATTLASTFYHILRYTDAYKTLCTEIRSSFNNEADITGERLVRLPFLNACIRETLRLLPPANGKTAQRTAPSCTIADTYIPAGTIVSADLYTIQRSTKYFVDPARFRPERWLEGAEKNGFNGDNKSASRPFLIGSRACIGRHMAQQSIRLIMAKLLWRYDFELLDRNRFIWERDAGSSLIYTDYKLSVHVKRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRH2</accession>
    <name>W6YRH2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_29275</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964075">
        <property type="protein sequence ID" value="EUC42047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691430.1">
        <property type="nucleotide sequence ID" value="XM_007693240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRH2"/>
    <dbReference type="STRING" id="930090.W6YRH2"/>
    <dbReference type="GeneID" id="19121477"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29275"/>
    <dbReference type="eggNOG" id="KOG0045">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006072_1_2_1"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000072">
        <property type="entry name" value="Cysteine proteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="8">
        <location>
            <begin position="159"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="594"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="664"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="860"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1022"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1058"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="594"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="618"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="669"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC42047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1077" mass="121817" checksum="4C7F00DBF672B6C9" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRL8</accession>
    <name>W6YRL8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_29221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964073">
        <property type="protein sequence ID" value="EUC42092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691375.1">
        <property type="nucleotide sequence ID" value="XM_007693185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRL8"/>
    <dbReference type="GeneID" id="19121461"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29221"/>
    <dbReference type="eggNOG" id="ENOG502T70T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_401696_0_0_1"/>
    <dbReference type="OrthoDB" id="5330058at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="604" mass="67876" checksum="32B9C1E0442C18F0" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6YRP3</accession>
    <name>W6YRP3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_9921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964192">
        <property type="protein sequence ID" value="EUC40158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693332.1">
        <property type="nucleotide sequence ID" value="XM_007695142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YRP3"/>
    <dbReference type="STRING" id="930090.W6YRP3"/>
    <dbReference type="GeneID" id="19129422"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_9921"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC40158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="57416" checksum="0CDDD46750256A26" modified="2014-04-16" version="1">MSNIVSNNALLIVLWITNPLKLFLYYVILAIYNVYFHPLRKFPGPKLRAASDWPYVASLLRGTSPQDMLEMHKKYGRVVRVAPNELTFVSPAAWTEIYGQKRRGQEELVKDEKYYSGMGEPTLLHSNQEQHAHLRKLLAHGFSNSSLQKQEAIIQKYLDVLMNTLRHHCQDGRSVVDLKDWVNFFVFDVIAYLTYGQSFNCLETRNVHSWIELVPKLARFMALMQAAQRLPIFVKPLFLLYGISTNLRSNVRTIQAISKEKVDYRLNSRPLVPDFMEKLIDEYKEGRMTMYQLDSNASFLMAAGSETLATVLTHAVFQLLTNPRTLEKLTAEIRTKFTCAAEINMSSVNECKYLLGCIEETMRIQAPSPATHPRYTNATGAVIDGFQVPGNVAVGIPIYAACKSALNFYDAESYIPERWTGEDPLYNHDLREAARIFSLGPRDCLGRNLAYAELKLVIARLVWHFDLEACFDSNWSDQKVYMVWEKPPFMVKLAPVQGSWAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6YT13</accession>
    <name>W6YT13_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiaminase-2/PQQC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_103087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964055">
        <property type="protein sequence ID" value="EUC42592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690875.1">
        <property type="nucleotide sequence ID" value="XM_007692685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YT13"/>
    <dbReference type="GeneID" id="19118218"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103087"/>
    <dbReference type="eggNOG" id="ENOG502QQ9D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055855_0_0_1"/>
    <dbReference type="OrthoDB" id="37730at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19357">
        <property type="entry name" value="TenA_E_At3g16990-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053261">
        <property type="entry name" value="Polyketide-peptide_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41813">
        <property type="entry name" value="REGULATOR PAB1642, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11955)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41813:SF2">
        <property type="entry name" value="REGULATOR PAB1642, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11955)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiaminase-2/PQQC" evidence="1">
        <location>
            <begin position="41"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC42592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="333" mass="38090" checksum="FEC94EB8A88BDEE9" modified="2014-04-16" version="1">MLTHHPGTAVAHRKGEIDPTDVPWALTTHLLAINHQQLLRVTRHPFLERAAKGSLPKSVIAQWLSNDRQYIEGYLSTLRNTLLLVQSTYKSTIAPDAEPDIETRLIKWLEAGIHNGEREIQFFHEVAEIYKIDFHPSPLQESLKSEGLRRYEALFNAVASQQPNPFIPWLEGAILLWSTEKVYYEAWSWARRQDTQSSPRGYENDMDGGAMRREFIPNWSNRDFMMFVEQLERIVNEGVSIAVNRDDKRWAEVKNRADPIWRALLDAEEAFWPNVPGSEGSLLEPGVQRGIDGKMDENTLRSTGDDVILNEHQGVRAGDITTMRSNQHDAVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6YTL6</accession>
    <name>W6YTL6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_107613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964133">
        <property type="protein sequence ID" value="EUC40878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692594.1">
        <property type="nucleotide sequence ID" value="XM_007694404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YTL6"/>
    <dbReference type="GeneID" id="19119085"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107613"/>
    <dbReference type="HOGENOM" id="CLU_2757416_0_0_1"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="70" mass="7935" checksum="893789A4DFB7CE4D" modified="2014-04-16" version="1">MRERQPSTGGDWKYRGRKALLYYICVRLLTIYSFWGVFWVDVASLLTAKNNFLATAKTLGSSAESVDKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>W6YU81</accession>
    <name>W6YU81_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_40658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964119">
        <property type="protein sequence ID" value="EUC41110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692365.1">
        <property type="nucleotide sequence ID" value="XM_007694175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YU81"/>
    <dbReference type="STRING" id="930090.W6YU81"/>
    <dbReference type="GeneID" id="19123923"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_40658"/>
    <dbReference type="eggNOG" id="ENOG502QRI8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029881_1_1_1"/>
    <dbReference type="OrthoDB" id="5584247at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052246">
        <property type="entry name" value="Cell_Polariz_PKAAnc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13155:SF1">
        <property type="entry name" value="A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13155">
        <property type="entry name" value="A-KINASE ANCHOR PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="173"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="365" mass="41741" checksum="AB079B10EB4B7730" modified="2014-04-16" version="1">MSHPDDKVTMDYGPARNRFPTLFEVLSRKTVAPLDLFSFYIYMRDQQRSVDYLDFWLDVSQHLQLCRLYVRRLHRSMIEGTPDLDNSNRYSTFAMDNAGEGPSNEKGDNMSDQRLSAFLRSERGSPNHSPQHSQGSNQTGDFQRPSPYASETPGDSNSPGHNSSIDNTQPGREDLRASAEKILYTYLLPGSEREIIIPQSILSDVQEAIEGPEQRADPELFDQAKDYVFQAMERDAYPGFLQNKGLGNLVPQSMMVRLIVGLISFFAAMWTSFILIFLDKSRATRCWIILPFTIAIYLIFTHQYMLDPIIALAGYSEYTFFDFNKIREPFVKKTLARRSLTVLLMFLVVTVALCCLFIFVPGKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6YUK5</accession>
    <name>W6YUK5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_106765</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 13">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964114">
        <property type="protein sequence ID" value="EUC41213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692273.1">
        <property type="nucleotide sequence ID" value="XM_007694083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YUK5"/>
    <dbReference type="STRING" id="930090.W6YUK5"/>
    <dbReference type="GeneID" id="19118916"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_106765"/>
    <dbReference type="eggNOG" id="KOG2691">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093932_0_1_1"/>
    <dbReference type="OrthoDB" id="282270at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001193">
        <property type="term" value="P:maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd10508">
        <property type="entry name" value="Zn-ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000016">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034012">
        <property type="entry name" value="Zn_ribbon_RPB9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="14">
        <location>
            <begin position="87"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="11">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC41213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="132" mass="14279" checksum="D8C4CEE5038764E1" modified="2014-04-16" version="1">MSSPAAQTSGVKGGKEPILFRFCSECSNLLFPREDKSENKLLFACRTCNFTEEAPSSCVMRHEIASTVGATAGVTAEVAQDPTLPRVQKQCTECGENEAVFFQSQQRTAETGMALYYVCAGCGHVTRPSDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6YVQ0</accession>
    <name>W6YVQ0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MalT-like TPR region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_71777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964318">
        <property type="protein sequence ID" value="EUC39589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_007695701.1"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="3671074at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="27097" checksum="23913237FBCC4C1C" modified="2014-04-16" version="1" fragment="single">MQKTVHVAFDGWSEEYREWEKWALLSELKGRYWESLGQHRLAETAHRKALLLSTEILGPEHLFTLASMHNLALVLNSQKKYEEAETINEQTLARYKKVLGTEHPSTLTSMHNLAWVLNSQGKCKEAEEVNWQTLVLREKVLGPKHPDTLASMSNLAWVLSSQRKYKEAEVMNRQTLALRENVLGSEHLDTLTSVYYLAYSLAQQHYIDEPLRLYQRASTGYDLILGEGHPTTLACC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6YW05</accession>
    <name>W6YW05_COCMI</name>
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        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_8595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964089">
        <property type="protein sequence ID" value="EUC41713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007693555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YW05"/>
    <dbReference type="GeneID" id="19126771"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_8595"/>
    <dbReference type="eggNOG" id="KOG1204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_11_1"/>
    <dbReference type="OrthoDB" id="153074at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF8">
        <property type="entry name" value="BENZIL REDUCTASE ((S)-BENZOIN FORMING) IRC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC41713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="30027" checksum="3364EBDBEFD6DC14" modified="2014-04-16" version="1">MSSKPQVVLVVGGTSGIGYAITQTILSGPYLPLNTKVVAFGLIDSSIKLEFTKQQRERLRIVEGDVTVAEDRELAMRTCFNVFGGLDTLVYCAGIITPIQRLEKLDIEAAKRSFDVNVFGAMSMVQLVLPHLRASKASHPHNYGRGKVIILSSACDSAVSYHGWMPYSTTKAALTRFISCLAHEEPLLSVQGVYPKLTRTKMIDGLVEGKYRGVMADHEIERFRIWDDMGDEIVEPPELCGDAVAKLALGLFEGGKSGETLYYDEHVPSKIAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWL3</accession>
    <name>W6YWL3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Short-chain dehydrogenase/reductase 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Retinal short-chain dehydrogenase/reductase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_110176</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964223">
        <property type="protein sequence ID" value="EUC39914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693563.1">
        <property type="nucleotide sequence ID" value="XM_007695373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWL3"/>
    <dbReference type="GeneID" id="19119556"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_110176"/>
    <dbReference type="eggNOG" id="KOG1201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_5_2_1"/>
    <dbReference type="OrthoDB" id="10253736at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052650">
        <property type="term" value="F:all-trans-retinol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05339">
        <property type="entry name" value="17beta-HSDXI-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000131">
        <property type="entry name" value="Short-chain dehydrogenase/reductase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00059620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EUC39914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="358" mass="38947" checksum="43E81DC7A7557C02" modified="2014-04-16" version="1">MAAALQNLINLVATSATRVALNPIVTTALLWILTKGPLQLRRQLANRVPALRDPTQYAQILKALKVCLALGTAGVLNKQLNRLALNAGRLRSDKARWNWNREVAVVTGGCSGIGELVVKKLISKDIRVAILDIRQLPPSLQSVANVTFFACDITNPNAVYSTAEKIKATLGAPTILVNNAGIFVPHTILNTSDDHLRRIFDVNVLSNWYTTKAFLPDMLQHNKGHIVTVASAASFVGIAGMADYTATKAAILSFHESLNQELRHQYNSPNVLTTSIHPNWVRTPLIASVEDELKKRGASIIEPTVVADSIVKSITSCSGGQVMLPSDISKITYVRGLPNWLQESLRDSVSKLINNGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWQ9</accession>
    <name>W6YWQ9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_71425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964216">
        <property type="protein sequence ID" value="EUC39964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693524.1">
        <property type="nucleotide sequence ID" value="XM_007695334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWQ9"/>
    <dbReference type="GeneID" id="19125188"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_71425"/>
    <dbReference type="eggNOG" id="ENOG502R9DT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068279_3_2_1"/>
    <dbReference type="OrthoDB" id="1022638at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC39964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="18259" checksum="C1D8AC60BC602596" modified="2014-04-16" version="1" fragment="single">ADHMSDSVTIHVGTTPDQYMVHSARLRKSSKFFEKALEKVSCQSFRSRRVIDLADENSACFKVYLHWLYDKTLPTMISQDLESDSNMEGSVDTEYHLLSNCYAMGERLMDNGFKNAVVDALVEARLISHTGNCWEPCVGTVTIIYTGTPEHSQARRLMINM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6YWZ3</accession>
    <name>W6YWZ3_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_10004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964205">
        <property type="protein sequence ID" value="EUC40044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693446.1">
        <property type="nucleotide sequence ID" value="XM_007695256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YWZ3"/>
    <dbReference type="GeneID" id="19117589"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_10004"/>
    <dbReference type="HOGENOM" id="CLU_1454142_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004886200" evidence="2">
        <location>
            <begin position="19"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC40044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="186" mass="19120" checksum="59183A8532111C30" modified="2014-04-16" version="1">MNFFLLLTSLVLASSVQARPAVLDTPAAMTPDLTSGALPEDITTSTVDTPEVPNLDTTSSDAGSGLLPDFPFKRRQTSTSSGSVTVGDILSSNSASGAISQRRQTSTSSGSISIGDILSSNSASGSIAQRRQTSTSSGSATVGDILSSNSASGVLPQRRQSPDVDVDTNTPYVVTLRLDFGDLFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXR6</accession>
    <name>W6YXR6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_109051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964173">
        <property type="protein sequence ID" value="EUC40349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007693140.1">
        <property type="nucleotide sequence ID" value="XM_007694950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXR6"/>
    <dbReference type="STRING" id="930090.W6YXR6"/>
    <dbReference type="GeneID" id="19119358"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_109051"/>
    <dbReference type="HOGENOM" id="CLU_1027330_0_0_1"/>
    <dbReference type="OrthoDB" id="3764174at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC40349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="265" mass="29226" checksum="E29224BC66B8461C" modified="2014-04-16" version="1">MQATTASARATIEAFHARLAAAEKQQHQAWEQQDQQQFQDMYSPCNSSSTFHDLQCGHRIQTEYTASCGGLCARPVQGYPFVCPTCLIDVVRAEVALQGLTLKLNHDEAVESAGSSQESEVRRVAEQYIAAMLRRGYRACKAVAKFDEPRLQFFDEFMRQDGFGGVVEEDCHKEEPVTPRKRPGTATARKAKQNGLDQTPRTLDFRDSATGHAPAEREKRADMNQAVGGAMGGNPSQSVETWVNLPPESAATEAVRKAMEAFSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6YXW1</accession>
    <name>W6YXW1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_6494</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964010">
        <property type="protein sequence ID" value="EUC44172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689301.1">
        <property type="nucleotide sequence ID" value="XM_007691111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YXW1"/>
    <dbReference type="STRING" id="930090.W6YXW1"/>
    <dbReference type="GeneID" id="19124974"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6494"/>
    <dbReference type="eggNOG" id="KOG0176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_4_2_1"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03753">
        <property type="entry name" value="proteasome_alpha_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000015">
        <property type="entry name" value="Proteasome subunit alpha type-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033812">
        <property type="entry name" value="Proteasome_alpha_type_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="244" mass="26644" checksum="3C9B3689EC7B0A5A" modified="2014-04-16" version="1">MVPRSEYDRGINTFSPEGRLFQVEYSLEAIKLGSTAIGVATGEGVILGVEKRVTSTLLETSSVEKIVEIDRHIGCAMSGLQADARSMIEHARVESQNHAFNYAEPLRVESCTQAICDLALRFGEGAEGEESIMSRPFGVALLIAGYDEDGPSLYHAEPSGTFYRYDAKAIGSGSEGAQAELQNEFHKSLTLAEAEVLTLKTLKQVMEEKLDSKNVQLASVTKDKGFRIYTDEEMAEVVGRLPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZF7</accession>
    <name>W6YZF7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_39019</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964043">
        <property type="protein sequence ID" value="EUC42973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690502.1">
        <property type="nucleotide sequence ID" value="XM_007692312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZF7"/>
    <dbReference type="GeneID" id="19123599"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39019"/>
    <dbReference type="eggNOG" id="ENOG502QSZ7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021993_1_0_1"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000308">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF6">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="106"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC42973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="500" mass="54082" checksum="FBCDA3E223A9832A" modified="2014-04-16" version="1">MSAPFHSLFDIQPASQITNPEPAYKKNSDKAPHHIGVLPDVELDNFSVKKDGNDRQPSASKQSSQNGAVTSKTLTELENSRPATPTHDDGFARERTWNADPMTKWRILCCCLIYFSNGMNDAVVGALIPYMEKHYHISYTIMSLVFVGTAAGFIIAAFFTNSVLGKFGRAKTLVISETIQLSAYIVLVCTPPYPLVVLSFFMLGFGAAINLALNNVYCSHTHPPSVILGLAHGSYGVGGIIAPIIGTAMASGGILWSRFYFIAVGVRICCIVFAAWAFWSFKEDTEDNLLETTTTQQTAAEEATSKLKNLKHALKNKVTFFGALFIFAYQGAEVSISGWFISYLINYRNGDPRTVGYVTAGFWGGITIGRFVLTHAAPRIGERKFVVILTLGTVGLQLLAWLTPNLIGNAVAVCLLGLLLGPIYPCASTIFSRLMPRNIQTTAIGFIAGAGSSGGAVAPFTTGILAQASGTWVLNPVCLGMYGAMLACWFALPRVRKRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6YZZ3</accession>
    <name>W6YZZ3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_107095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI964120">
        <property type="protein sequence ID" value="EUC41104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007692391.1">
        <property type="nucleotide sequence ID" value="XM_007694201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6YZZ3"/>
    <dbReference type="GeneID" id="19118980"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_107095"/>
    <dbReference type="eggNOG" id="ENOG502SHVI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007426_5_0_1"/>
    <dbReference type="OrthoDB" id="4934715at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="23"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC41104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="732" mass="83586" checksum="000DC6A9096986EB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0E2</accession>
    <name>W6Z0E2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Smr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_7159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964030">
        <property type="protein sequence ID" value="EUC43400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690066.1">
        <property type="nucleotide sequence ID" value="XM_007691876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0E2"/>
    <dbReference type="STRING" id="930090.W6Z0E2"/>
    <dbReference type="GeneID" id="19125196"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7159"/>
    <dbReference type="eggNOG" id="KOG2401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023589_0_0_1"/>
    <dbReference type="OrthoDB" id="443981at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052772">
        <property type="entry name" value="Endo/PolyKinase_Domain-Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058864">
        <property type="entry name" value="UBA_10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46535">
        <property type="entry name" value="NEDD4-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46535:SF1">
        <property type="entry name" value="NEDD4-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26286">
        <property type="entry name" value="UBA_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="2">
        <location>
            <begin position="438"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="531" mass="57468" checksum="A720F80284DD49A2" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z0E4</accession>
    <name>W6Z0E4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pigment biosynthesis protein Ayg1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_7165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964030">
        <property type="protein sequence ID" value="EUC43405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690068.1">
        <property type="nucleotide sequence ID" value="XM_007691878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z0E4"/>
    <dbReference type="STRING" id="930090.W6Z0E4"/>
    <dbReference type="GeneID" id="19125199"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7165"/>
    <dbReference type="eggNOG" id="ENOG502S29V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053723_1_0_1"/>
    <dbReference type="OrthoDB" id="5409895at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000145">
        <property type="entry name" value="Pigment biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010520">
        <property type="entry name" value="FrsA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050261">
        <property type="entry name" value="FrsA_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946:SF12">
        <property type="entry name" value="CONIDIAL PIGMENT BIOSYNTHESIS PROTEIN AYG1 (AFU_ORTHOLOGUE AFUA_2G17550)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06500">
        <property type="entry name" value="FrsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC43405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="45659" checksum="EB790CCAD5CBBF12" modified="2014-04-16" version="1">MPDGTWILGDLFTKEYGHRGSIQKLWEQRWKFPCTKGVYPFHDGKFEDFEPIFKHLIDNNINDPYEDAYTNAFLPTAQRLAKEAQDMESKDKEAARKLYLNANAVYRLSRFPYIGTDLKKQVFEEQKSVYLRGTKLWDEPMLDISIPHTHASNGDGPQIPVYVRKPGGDGPFPTVLLITGLDGHRPDNTERTQEHLNRGWATVLCDIPGTTVDCPANRRDPLSSDRLFSSILDWIAQTPYLDAKKVLAWGLSAGGYYAIRLAHTHREKLVGSVGHGAGTHHYIGREWLAQVEKHEYPFGLEEAYRQKYGYASFEEVMEKCQDEFSLVTGKGEGVAVVGAGMQSCRLLLVNGVLDGCMPVEDSMLLAEYGSPKEMRFLRERLHMGYPEANATVYPWMEGVMRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z194</accession>
    <name>W6Z194_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_28071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964028">
        <property type="protein sequence ID" value="EUC43478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690007.1">
        <property type="nucleotide sequence ID" value="XM_007691817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z194"/>
    <dbReference type="STRING" id="930090.W6Z194"/>
    <dbReference type="GeneID" id="19121235"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28071"/>
    <dbReference type="eggNOG" id="ENOG502RJF6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066466_0_1_1"/>
    <dbReference type="OrthoDB" id="2862635at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070007">
        <property type="term" value="F:glutamic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13426">
        <property type="entry name" value="Peptidase_G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="entry name" value="Peptidase G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536:SF1">
        <property type="entry name" value="ASPERGILLOPEPSIN, PUTAITVE (AFU_ORTHOLOGUE AFUA_7G01200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00977">
        <property type="entry name" value="SCYTLDPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887047" evidence="2">
        <location>
            <begin position="18"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600250-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="273" mass="29703" checksum="82D84F1B0E395B21" modified="2014-04-16" version="1">MKLFIAFVVALTSSVLAEGVQARVHGNHQYLPQPFVEDSTALGIRCSRSVARDTDKEHRVVTDGTWSGAIIFKKLCAGNFVSVTGRFTIPIPKHTCTSNDTEKGSAWVGISNYTYGSMLQAGVDWEVERSGNVTYSAWYEWVPYLTTYLDDFEVRGGDVMQVDIATTTPTTANVRLINVSTGKDISIDATAAPDSFLTGDNAEWVMEDFSDEGKLPPLADFGEVVFTNASAKTSTGWVEDLGGATIINMVQDGKLVVDTHIPSLSQIAIKYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1A2</accession>
    <name>W6Z1A2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_38555</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KI964027">
        <property type="protein sequence ID" value="EUC43488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689975.1">
        <property type="nucleotide sequence ID" value="XM_007691785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1A2"/>
    <dbReference type="STRING" id="930090.W6Z1A2"/>
    <dbReference type="ESTHER" id="cocca-w6yhs1">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="19123500"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38555"/>
    <dbReference type="eggNOG" id="KOG1516">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_6_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012972036" description="Carboxylic ester hydrolase" evidence="4">
        <location>
            <begin position="16"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="18"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC43488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="549" mass="60727" checksum="46913C96DFB30023" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z1M8</accession>
    <name>W6Z1M8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PH domain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_105831</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964097">
        <property type="protein sequence ID" value="EUC41549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691930.1">
        <property type="nucleotide sequence ID" value="XM_007693740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z1M8"/>
    <dbReference type="STRING" id="930090.W6Z1M8"/>
    <dbReference type="GeneID" id="19118757"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_105831"/>
    <dbReference type="eggNOG" id="KOG2868">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058649_0_1_1"/>
    <dbReference type="OrthoDB" id="440673at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13182">
        <property type="entry name" value="EVH1-like_Dcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
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    <sequence length="263" mass="29486" checksum="A347365B6AF27AF9" modified="2014-04-16" version="1">MAPYRKARASQPQQPPPSDYETDAIPSVDVPLPPPRSNEELNLSVLRRQYPSLASIEHVTPYAALYTFNLETQQWEKMGVEGTLFICQLTPSPMGAERYCAIILNRRGLDNFYEELTSSDEMEISDPYVIIQGEQVYGIWIFADPPPSSTANCRQETAAKMMAVADRAKASRAALHGSPDAVSSTPMGRQLSLRELFGQHREQDADFSLHHHDSHPMPSMPHPPQQHQHQHQHQPYMTHGGPAQTDVLGQLFMRAKQNHNGLG</sequence>
</entry>
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    <accession>W6Z1R3</accession>
    <name>W6Z1R3_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
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    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_8705</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
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            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12 13">ATCC 44560</strain>
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    </reference>
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        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
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    </comment>
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        <property type="nucleotide sequence ID" value="XM_007693683.1"/>
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    <sequence length="2010" mass="219852" checksum="72175282BD6881B3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z206</accession>
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            <taxon>Ascomycota</taxon>
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            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963977">
        <property type="protein sequence ID" value="EUC45792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687667.1">
        <property type="nucleotide sequence ID" value="XM_007689477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z206"/>
    <dbReference type="GeneID" id="19123046"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36496"/>
    <dbReference type="eggNOG" id="ENOG502RXYE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029564_0_0_1"/>
    <dbReference type="OrthoDB" id="2448307at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC45792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="339" mass="38846" checksum="C9D8EB96714ABC1B" modified="2014-04-16" version="1">MYMPNTRWTWAFMLTAIAQVTIALALESYVFGKFQNEIHFAAEGAGANETRTIPTFLAVFMFGYIYQLFLTWDALRLKNTIQVIGLVLYNIGILVYAGIQFDQIKDAADDLNDSAFIPAFFWADVKPMLIALPCLMALATVIFAFEAWKLYDEFAWTIYKRISADTRLKKRYLTYQIYIALLKFDFFFFLAFTVQFLVVVENTKTVEQALTAAALVATFILLFLAAWWVRRESFAGMISIIIVYFISMGYFLFKLIRMWVADASRQEDYKPARKSLTAFAILTILLLICTIVTACLCTHNFNKGLKPHINDKVVQNDKPYSTEMPSLSGPVPSQRMEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z280</accession>
    <name>W6Z280_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_36459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963976">
        <property type="protein sequence ID" value="EUC45857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687623.1">
        <property type="nucleotide sequence ID" value="XM_007689433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z280"/>
    <dbReference type="GeneID" id="19123033"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_36459"/>
    <dbReference type="eggNOG" id="ENOG502TG2W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_521740_0_0_1"/>
    <dbReference type="OrthoDB" id="3695160at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="535" mass="58229" checksum="4E14E05B2C8BE098" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z2W4</accession>
    <name>W6Z2W4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL46</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_39898</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL46 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964077">
        <property type="protein sequence ID" value="EUC42004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691483.1">
        <property type="nucleotide sequence ID" value="XM_007693293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z2W4"/>
    <dbReference type="STRING" id="930090.W6Z2W4"/>
    <dbReference type="GeneID" id="19123771"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_39898"/>
    <dbReference type="eggNOG" id="KOG4548">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040204_1_1_1"/>
    <dbReference type="OrthoDB" id="414075at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04661">
        <property type="entry name" value="NUDIX_MRP_L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000018">
        <property type="entry name" value="39S ribosomal protein L46, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040008">
        <property type="entry name" value="Ribosomal_mL46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021757">
        <property type="entry name" value="Ribosomal_mL46_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033650">
        <property type="entry name" value="Ribosomal_mL46_NUDIX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11788">
        <property type="entry name" value="MRP-L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL46 N-terminal" evidence="9">
        <location>
            <begin position="60"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="167"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC42004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="337" mass="38338" checksum="D083E7508D27A42C" modified="2014-04-16" version="1">MNTGQQATRRLASRAGPSTCRSCRDTITRTYASAAAAVQTPDQTTQHVPPVAQASPSTAYAVNAGVVLSRPPQITRDLHPFESAFFLYQKRLNERLALPFTRYFYVKKRTPADLEWKRKMKQRLTPARDIGRYKGYGDEAWNDELLVGAPESDFEHQVGKLLEDAEQSGLEDAPDTTGANKMEREPVEKPMPRVTEADKKNDTKSLNRALQRTLYLLVKNKEGQWQFPQDRLKDEHLHGAANRIITSTGGVNMNTWLVGHVPIGHYQLEYREPRPSGSLKEYGAKTFFMKARIMAGQVDLKENKLGLQDFKWLAKEELQKEVDGSYWRSIKNMLAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z358</accession>
    <name>W6Z358_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Potassium transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_4670</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TrkH potassium transport family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963970">
        <property type="protein sequence ID" value="EUC46162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687257.1">
        <property type="nucleotide sequence ID" value="XM_007689067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z358"/>
    <dbReference type="STRING" id="930090.W6Z358"/>
    <dbReference type="GeneID" id="19124332"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4670"/>
    <dbReference type="eggNOG" id="KOG1341">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005947_0_1_1"/>
    <dbReference type="OrthoDB" id="9999863at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140107">
        <property type="term" value="F:high-affinity potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004773">
        <property type="entry name" value="K/Na_transp_Trk1/HKT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015958">
        <property type="entry name" value="Trk1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051143">
        <property type="entry name" value="TrkH_K-transport"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00934">
        <property type="entry name" value="2a38euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064:SF30">
        <property type="entry name" value="HIGH-AFFINITY POTASSIUM TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064">
        <property type="entry name" value="POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002450">
        <property type="entry name" value="K+_transpter_TRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="4 10" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="430"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="630"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="684"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="127"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="294"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR002450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC46162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="859" mass="96786" checksum="B0E96BA94FF47827" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3J7</accession>
    <name>W6Z3J7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_29120</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Non-catalytic component of the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964069">
        <property type="protein sequence ID" value="EUC42199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007691260.1">
        <property type="nucleotide sequence ID" value="XM_007693070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3J7"/>
    <dbReference type="STRING" id="930090.W6Z3J7"/>
    <dbReference type="GeneID" id="19121443"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_29120"/>
    <dbReference type="eggNOG" id="KOG0185">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072435_0_1_1"/>
    <dbReference type="OrthoDB" id="10248542at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03760">
        <property type="entry name" value="proteasome_beta_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000014">
        <property type="entry name" value="Proteasome subunit beta type-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016295">
        <property type="entry name" value="Proteasome_beta4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF6">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001213">
        <property type="entry name" value="Psome_endopept_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="260" mass="28917" checksum="8F7A0DD21C0D5BF9" modified="2014-04-16" version="1">MNHLPQAWGRPRDDVYGAYDPSHFSSDGPNQHTQSPIVTGTSVLAAKFKDGVVIAADNLASYGSLARFTDVKRLRKFNDEVVVGFGGDVSDMQYIDRLLNSLDIRENYSSSENSLNAKNLHTYLAKVMYNRRSKFDPLWNHLLIVGMDGESKPFLASADLLGTTFTSPSLATGFGAHLAQPILRTILPDEAAVENVTKEQAVDKIKECMKVLFYRDARSMDKYSIAVVTKEGVELDENVKLENQSWAFADRIRGYGTQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3M9</accession>
    <name>W6Z3M9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="15">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">COCMIDRAFT_6321</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="15"/>
    <dbReference type="EMBL" id="KI964006">
        <property type="protein sequence ID" value="EUC44343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007690927.1"/>
    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z3M9"/>
    <dbReference type="GeneID" id="19124921"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_6321"/>
    <dbReference type="eggNOG" id="KOG2204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003818_0_0_1"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
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        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017001">
        <property type="term" value="P:antibiotic catabolic process"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:carbohydrate metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002137">
        <property type="entry name" value="Beta-lactam_class-D_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF101">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00337">
        <property type="entry name" value="BETA_LACTAMASE_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="13" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 15 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="470"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="560"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="384"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC44343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="569" mass="64959" checksum="DF7DD0964729DA57" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3N2</accession>
    <name>W6Z3N2_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_93018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688933.1"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:translation release factor activity, codon nonspecific"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:mitochondrial translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Mito_Release_Factor_mL62"/>
    </dbReference>
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        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075:SF54">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110916">
        <property type="entry name" value="Peptidyl-tRNA hydrolase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="89"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC46362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="220" mass="23963" checksum="1E71FCBD6023652B" modified="2014-04-16" version="1">MRLQRRLILRPVVPVSCIAPVRCSPPTTRLPRRIACCCCYYSSSSSSSSSSSSSPSGSHGHGADDGLDAARTWLAALHAQTIPLETIGELTFSRSSGPGGQNVNKVSSKATLKVPLDALLPHVPAAMHSQIKHLRYLAPRSNTIVVHADDSRKQSDNARSCYRRLYEAIVLAARSAVPAEASPEQAQRVNSLQKSNNERRLKTKKLHSAKKSSRRTRTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3R7</accession>
    <name>W6Z3R7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_48590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964001">
        <property type="protein sequence ID" value="EUC44605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688902.1">
        <property type="nucleotide sequence ID" value="XM_007690712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3R7"/>
    <dbReference type="STRING" id="930090.W6Z3R7"/>
    <dbReference type="GeneID" id="19124409"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_48590"/>
    <dbReference type="eggNOG" id="ENOG502R2PD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_6_2_1"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="31"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="119" mass="13431" checksum="21EFFC021EF0B5DA" modified="2014-04-16" version="1" fragment="single">IRIMCIMPAQDAHAPIVIHVAHCPIDTDEHYIALSYCWGVDDTQEQIVMAGQKMTVRRNLAEAIRVIRSHNIIVPVWIDALSINQKDLVERARQVPRMGEIYDFATAVFSYIGNPTGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3V3</accession>
    <name>W6Z3V3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Terpene synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_37699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964004">
        <property type="protein sequence ID" value="EUC44423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689029.1">
        <property type="nucleotide sequence ID" value="XM_007690839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3V3"/>
    <dbReference type="GeneID" id="19123306"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37699"/>
    <dbReference type="eggNOG" id="ENOG502SPY5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047266_1_0_1"/>
    <dbReference type="OrthoDB" id="3004402at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887139" description="Terpene synthase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="44198" checksum="CA45D6CBFD1C3569" modified="2014-04-16" version="1">MNSLLNLVIFVLEQLLLVAPRDHVYAAAVAYAYDPVPNIPQYIRPKYASFPQHASRPNEHIKNNTIRLRPQAAGLPYRSSFDYVRAAKYWKANLEETIKVLELITTDTSTVDVEVGNGITLAKLARKELRPGLENRMVIATSHMFPSGDERQIRIIATLMIMYFVFDALSDLRDDFFSRFDGPKARRSQRTPSALQNHLDETVAGIYEEDAAGGNGGHEMLEALRGAFRCVHPEGNFPTVDSYLAFRRLNVGARFVIAAAKFTIKSNVDVSDPRFARFLSLIGDHLGLVNDLASYEKEARALSTGETKDMINIVAVMHNLMSLPSEKAAKAAAFSYLLQVETWIMEEIERLAAWEKLKDEEWWFLEAVFLSATGNTFFCMTSSRYSGEAAKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z3Y3</accession>
    <name>W6Z3Y3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Double-strand break repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">COCMIDRAFT_4499</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Core component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. Within the MRN complex, MRE11 possesses both single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. MRE11 first endonucleolytically cleaves the 5' strand at DNA DSB ends to prevent non-homologous end joining (NHEJ) and licence HR. It then generates a single-stranded DNA gap via 3' to 5' exonucleolytic degradation, which is required for single-strand invasion and recombination.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the MRN complex composed of two heterodimers RAD50 and MRE11 associated with a single NBS1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 17">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17 19">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687017.1">
        <property type="nucleotide sequence ID" value="XM_007688827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z3Y3"/>
    <dbReference type="STRING" id="930090.W6Z3Y3"/>
    <dbReference type="GeneID" id="19124261"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_4499"/>
    <dbReference type="eggNOG" id="KOG2310">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009535_1_1_1"/>
    <dbReference type="OrthoDB" id="30417at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140445">
        <property type="term" value="C:chromosome, telomeric repeat region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030437">
        <property type="term" value="P:ascospore formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010791">
        <property type="term" value="P:DNA double-strand break processing involved in repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990918">
        <property type="term" value="P:double-strand break repair involved in meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035753">
        <property type="term" value="P:maintenance of DNA trinucleotide repeats"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010780">
        <property type="term" value="P:meiotic DNA double-strand break formation involved in reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097552">
        <property type="term" value="P:mitochondrial double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062176">
        <property type="term" value="P:R-loop processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000011">
        <property type="entry name" value="Double-strand break repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.110">
        <property type="entry name" value="Mre11, capping domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003701">
        <property type="entry name" value="Mre11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038487">
        <property type="entry name" value="Mre11_capping_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007281">
        <property type="entry name" value="Mre11_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00583">
        <property type="entry name" value="mre11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139:SF1">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04152">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000882">
        <property type="entry name" value="DSB_repair_MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01347">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 17 19" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 17 19" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 17 19" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="11 17 19" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10 17 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 17 19" id="KW-0464">Manganese</keyword>
    <keyword evidence="15 17 19" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 17 19" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14 17 19" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mre11 DNA-binding" evidence="21">
        <location>
            <begin position="295"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="532"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="587"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="620"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="663"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="693"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="720"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00064981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR000882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000882-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU003447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EUC46467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="745" mass="84418" checksum="43F2231F556B0872" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4S9</accession>
    <name>W6Z4S9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_26751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963993">
        <property type="protein sequence ID" value="EUC44985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688472.1">
        <property type="nucleotide sequence ID" value="XM_007690282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4S9"/>
    <dbReference type="GeneID" id="19120989"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26751"/>
    <dbReference type="HOGENOM" id="CLU_2026300_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC44985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="122" mass="13672" checksum="AAF489D305632F0A" modified="2014-04-16" version="1">MHIISPIPNGKTTGPKHHHHQQQQQAYDSHQNNPQTHPSSKLKRTYYVTHARSPQCTAPHTQHATLAAPTGTVHPTHPPWHHTNAPHSPPHSHSAARACALSKRVDTTRHLPSRALDREVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z4X6</accession>
    <name>W6Z4X6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-coumarate-CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_103021</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964054">
        <property type="protein sequence ID" value="EUC42654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690855.1">
        <property type="nucleotide sequence ID" value="XM_007692665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z4X6"/>
    <dbReference type="STRING" id="930090.W6Z4X6"/>
    <dbReference type="GeneID" id="19118207"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_103021"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OrthoDB" id="1898221at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="33"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="442"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="57974" checksum="E9A786FD24E516A4" modified="2014-04-16" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z530</accession>
    <name>W6Z530_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TRUD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">COCMIDRAFT_28744</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964053">
        <property type="protein sequence ID" value="EUC42669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690801.1">
        <property type="nucleotide sequence ID" value="XM_007692611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z530"/>
    <dbReference type="STRING" id="930090.W6Z530"/>
    <dbReference type="GeneID" id="19121365"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28744"/>
    <dbReference type="eggNOG" id="KOG2339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005281_0_0_1"/>
    <dbReference type="OrthoDB" id="447290at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02576">
        <property type="entry name" value="PseudoU_synth_ScPUS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="entry name" value="TruD, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056963">
        <property type="entry name" value="PUS7L_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00094">
        <property type="entry name" value="tRNA_TruD_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326:SF21">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE PUS7L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23943">
        <property type="entry name" value="PUS7L_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037016">
        <property type="entry name" value="Pseudouridin_synth_euk_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRUD" evidence="4">
        <location>
            <begin position="420"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="249"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="588"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="740"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EUC42669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="801" mass="89247" checksum="4F7C31FC27031712" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z577</accession>
    <name>W6Z577_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_96972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963995">
        <property type="protein sequence ID" value="EUC44908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688614.1">
        <property type="nucleotide sequence ID" value="XM_007690424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z577"/>
    <dbReference type="GeneID" id="19128960"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_96972"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF236">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC44908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="317" mass="34914" checksum="F8999A685B957B03" modified="2014-04-16" version="1">MGNQFSQIFPPAPTFTESSLPDLKDKVFIVTGASAGVGKELARLLYSRNGTVYAAARSTEKTTAALAWIKEQHPSSKGKLAHLHLDLNDLEGIKPSVENFLAQESRLDVLVNNAGVMMTPQGSKTKQGYEQQLGTNCVAPFLFTKLLTPLLVSTAKKEPAGSVRVVWVSSSVAHVAAPKGGLDMQNLDYKKDASPTAKYAVSKGGNILHSIEYRKRYGGEGVVSVPLNPGNLTTDLQRYIPTWQRLLLKLLTYPAVNGAYTELFASLAPEAAKLKESEWVVPWGRVVPLREDYYSDLGKENAKVFWEWSEQQVERYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5H2</accession>
    <name>W6Z5H2_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_91396</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC47017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686518.1">
        <property type="nucleotide sequence ID" value="XM_007688328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5H2"/>
    <dbReference type="GeneID" id="19127873"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91396"/>
    <dbReference type="eggNOG" id="ENOG502SHJ2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019101_0_0_1"/>
    <dbReference type="OrthoDB" id="2988756at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF152">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="24"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="281"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC47017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="345" mass="38661" checksum="5A9D4BC8837EE7AB" modified="2014-04-16" version="1">MSDPNAILVECRVEYAMGSAIIGLRFFARWKTQGWRGFYWDDFFAFSSWVFFTLIYAMVEFLSVNEAPIAMTQEQRESLPPAMRKSMREGAKVMFASFYFLIFLVWSLKGCLIILFLHFTKDRFLYRYVQVVGGLSVAAFISAVVTQTTHCLPLEKNWQVLPDPGKECSAGVVINIVIAVGNVLVDAMLLVVPVWMLKDTKIGVWRKIKIIFLLSLDLFVMGMATARCVLSIGTSVQVALASVWAQREAVVSIFAVNAPVIHGLFRSKTWKLEESSCESSSSQTSTELSSTRKKTNIGMAMTETETSSRASTFDSVTDESPVSSPSQLRYSPHGKNKKGRPMRMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z5T3</accession>
    <name>W6Z5T3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein arginine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">COCMIDRAFT_28541</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KI964045">
        <property type="protein sequence ID" value="EUC42914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690557.1">
        <property type="nucleotide sequence ID" value="XM_007692367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z5T3"/>
    <dbReference type="STRING" id="930090.W6Z5T3"/>
    <dbReference type="GeneID" id="19121324"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_28541"/>
    <dbReference type="eggNOG" id="KOG0822">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010247_2_1_1"/>
    <dbReference type="OrthoDB" id="1368803at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071521">
        <property type="term" value="C:Cdc42 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
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</entry>
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                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Wang R."/>
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                <person name="Dhillon B."/>
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                <person name="Ciuffetti L.M."/>
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</entry>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Ohm R.A."/>
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                <person name="Han J."/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="69"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="111"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="150" mass="16029" checksum="C3EE0F929AC8BE5E" modified="2014-04-16" version="1">MSESDDAEICLRVLASTAILYRPISVPELVALVEQLEDLDDLESVQEVIGFYGIRPTLSEEWSACLQTLEGHSGEVSSVAFSPDSTQLASASWDSTVKIWDAASGACLQTLEGHSSYLTLVAFSPDSTRLASASHDSTVKIWDATSGACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6D4</accession>
    <name>W6Z6D4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Peroxisomal hydratase-dehydrogenase-epimerase</fullName>
            <ecNumber evidence="5">1.1.1.n12</ecNumber>
            <ecNumber evidence="6">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Multifunctional beta-oxidation protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">COCMIDRAFT_7403</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Second trifunctional enzyme acting on the beta-oxidation pathway for fatty acids, possessing hydratase-dehydrogenase-epimerase activities. Converts trans-2-enoyl-CoA via D-3-hydroxyacyl-CoA to 3-ketoacyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a (3R)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32711"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.n12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.n12" evidence="5"/>
    <dbReference type="EC" id="4.2.1.119" evidence="6"/>
    <dbReference type="EMBL" id="KI964039">
        <property type="protein sequence ID" value="EUC43109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690350.1">
        <property type="nucleotide sequence ID" value="XM_007692160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6D4"/>
    <dbReference type="STRING" id="930090.W6Z6D4"/>
    <dbReference type="GeneID" id="19125277"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7403"/>
    <dbReference type="eggNOG" id="KOG1206">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_18_0_1"/>
    <dbReference type="OrthoDB" id="3592703at2759"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018812">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05353">
        <property type="entry name" value="hydroxyacyl-CoA-like_DH_SDR_c-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000410">
        <property type="entry name" value="Peroxisomal multifunctional beta-oxidation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000013">
        <property type="entry name" value="Peroxisomal multifunctional enzyme type 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000185">
        <property type="entry name" value="peroxisomal multifunctional enzyme type 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051687">
        <property type="entry name" value="Peroxisomal_Beta-Oxidation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024:SF2">
        <property type="entry name" value="SCP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ketoreductase" evidence="22">
        <location>
            <begin position="315"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="766"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00052025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00055743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00073871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00081853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EUC43109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="904" mass="97540" checksum="D54C8A8900F02E0D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6J5</accession>
    <name>W6Z6J5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF833 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_90342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686092.1">
        <property type="nucleotide sequence ID" value="XM_007687902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6J5"/>
    <dbReference type="GeneID" id="19127663"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90342"/>
    <dbReference type="eggNOG" id="KOG2342">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047037_0_2_1"/>
    <dbReference type="OrthoDB" id="191601at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="SER/THR-RICH PROTEIN T10 IN DGCR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985:SF8">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC47357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35964" checksum="B417558EDDB30DCB" modified="2014-04-16" version="1">MCIAILTTAHPDYPFILLNNRDEYLHRPTAEATWWPSPDTQVLGGYDLHRPVHGTWMGVTRQGRIAVLTNYREEDEKIVEGARSRGLIPNAWLKSDPAKGETADEFAKRMIEQDGVEGVGGFSLCYGFMQDVVKKGKGLAIVSNRTPDVHGLVRLLQTPDETHALSNAAYSDRSWPKVIHGEEWTKKAIAESIAANESRDQFIQRLLALLRTDTMPRQKENEEWDMYLNQLRHSIFIPAIGRDHLEEHKMPAHEIGDVVKNKAADAASGCYGTQKNIIVLCDHKGKVTYLERTLYDVDAKPIEDGKGDRVFEFQIEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z6R9</accession>
    <name>W6Z6R9_COCMI</name>
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        <recommendedName>
            <fullName evidence="2">DUF7514 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_7334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964036">
        <property type="protein sequence ID" value="EUC43234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007690251.1">
        <property type="nucleotide sequence ID" value="XM_007692061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z6R9"/>
    <dbReference type="STRING" id="930090.W6Z6R9"/>
    <dbReference type="GeneID" id="19125257"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_7334"/>
    <dbReference type="eggNOG" id="ENOG502S6DG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021115_1_0_1"/>
    <dbReference type="OrthoDB" id="5413703at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055936">
        <property type="entry name" value="DUF7514"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611:SF1">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24355">
        <property type="entry name" value="DUF7514"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7514" evidence="2">
        <location>
            <begin position="220"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC43234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="609" mass="68769" checksum="57B2DD2DFE006195" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z7J0</accession>
    <name>W6Z7J0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_5070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963978">
        <property type="protein sequence ID" value="EUC45738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687709.1">
        <property type="nucleotide sequence ID" value="XM_007689519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z7J0"/>
    <dbReference type="GeneID" id="19124487"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_5070"/>
    <dbReference type="eggNOG" id="ENOG502QPR9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005049_0_1_1"/>
    <dbReference type="OrthoDB" id="3162439at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="42"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC45738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="664" mass="75504" checksum="54D6EB4E6EFF7CC3" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z809</accession>
    <name>W6Z809_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_88860</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="8"/>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685603.1">
        <property type="nucleotide sequence ID" value="XM_007687413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z809"/>
    <dbReference type="STRING" id="930090.W6Z809"/>
    <dbReference type="GeneID" id="19127359"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88860"/>
    <dbReference type="eggNOG" id="KOG2623">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024003_4_0_1"/>
    <dbReference type="OrthoDB" id="337870at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000001">
        <property type="entry name" value="Tyrosine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000227">
        <property type="entry name" value="Tyrosine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032005">
        <property type="entry name" value="TyrRSs_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF0">
        <property type="entry name" value="TYROSINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="TYROSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="tRNA-synt_1b"/>
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    </dbReference>
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        <property type="entry name" value="TyrRSs_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
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        <property type="entry name" value="Nucleotidylyl transferase"/>
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    </dbReference>
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        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
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    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="490"/>
            <end position="590"/>
        </location>
    </feature>
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            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="464"/>
            <end position="491"/>
        </location>
    </feature>
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        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC47857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="605" mass="66644" checksum="C4F425F73855A263" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8D4</accession>
    <name>W6Z8D4_COCMI</name>
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        <recommendedName>
            <fullName evidence="3 10">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_34565</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 10">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
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    <dbReference type="EMBL" id="KI963946">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="STRING" id="930090.W6Z8D4"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_34565"/>
    <dbReference type="eggNOG" id="KOG2628">
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    </dbReference>
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    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR025770">
        <property type="entry name" value="PPMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51564">
        <property type="entry name" value="SAM_ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="282"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
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            <end position="472"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="300"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC48002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="829" mass="90377" checksum="2225EEAA68DD2D56" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z8U5</accession>
    <name>W6Z8U5_COCMI</name>
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        <recommendedName>
            <fullName evidence="3">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_2935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007687106.1"/>
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    <dbReference type="KEGG" id="bor:COCMIDRAFT_2935"/>
    <dbReference type="eggNOG" id="ENOG502SR7C">
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    </dbReference>
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    <dbReference type="OrthoDB" id="2851338at2759"/>
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    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC48147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="29357" checksum="D3A02E0051351BE5" modified="2014-04-16" version="1">MAPPGILWVSSRITHPERLSADKFSDWYENDHIKDVLALPGATAAVRYQAVERPVKDGGEERAYSGEMPWLVVYELPDMVGFRESDGFKDIAQRNPPSQEQIETIYVNTQFSVRFYEEVQLFEGEKAKENGPVKFIISGALEPPSDTASTADFDRWYREEHIPLLSRIPGFIRSRRYEVKTAYTLNQLQPSDDMEKVPKYYALHEFGGEALPWKQIEESVGTEWAKKVMASVQKAEVGWYKVKRVFPESEWGNVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>W6Z935</accession>
    <name>W6Z935_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_38040</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964012">
        <property type="protein sequence ID" value="EUC44069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689401.1">
        <property type="nucleotide sequence ID" value="XM_007691211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6Z935"/>
    <dbReference type="GeneID" id="19123380"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38040"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000061">
        <property type="entry name" value="MFS sugar transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="539"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="77"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="598" mass="66044" checksum="F8313779A3CC10A5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA62</accession>
    <name>W6ZA62_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_27215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI964004">
        <property type="protein sequence ID" value="EUC44424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689021.1">
        <property type="nucleotide sequence ID" value="XM_007690831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA62"/>
    <dbReference type="GeneID" id="19121081"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_27215"/>
    <dbReference type="HOGENOM" id="CLU_2183484_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC44424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="109" mass="11729" checksum="EE3D3FCB8972C67D" modified="2014-04-16" version="1">MSPLVGETESHPSLSDIPYLYGTEKTWFPRLATMNRISAGFPGCGTPTVHNEFGIFSAPLSCINITLGQPMCTSASGIQPDSIDSTGRIEVFVTSSANTGQQRVFLFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZA92</accession>
    <name>W6ZA92_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_92092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963962">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_007688587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZA92"/>
    <dbReference type="STRING" id="930090.W6ZA92"/>
    <dbReference type="GeneID" id="19128008"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92092"/>
    <dbReference type="eggNOG" id="ENOG502STHN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_329813_0_0_1"/>
    <dbReference type="OrthoDB" id="3556832at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="776"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="870" mass="96029" checksum="DD4A5D217F199C2B" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZAD4</accession>
    <name>W6ZAD4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tyrosinase</fullName>
            <ecNumber evidence="3">1.14.18.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_98124</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2 L-dopa + O2 = 2 L-dopaquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:34287"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57504"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosine + O2 = L-dopaquinone + H2O</text>
            <dbReference type="Rhea" id="RHEA:18117"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosinase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.18.1" evidence="3"/>
    <dbReference type="EMBL" id="KI964003">
        <property type="protein sequence ID" value="EUC44489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688996.1">
        <property type="nucleotide sequence ID" value="XM_007690806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZAD4"/>
    <dbReference type="STRING" id="930090.W6ZAD4"/>
    <dbReference type="GeneID" id="19129190"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_98124"/>
    <dbReference type="eggNOG" id="ENOG502R1BY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013691_3_0_1"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004503">
        <property type="term" value="F:tyrosinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042438">
        <property type="term" value="P:melanin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041640">
        <property type="entry name" value="Tyrosinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF76">
        <property type="entry name" value="SHKT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18132">
        <property type="entry name" value="Tyrosinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0470">Melanin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004889854" description="tyrosinase" evidence="12">
        <location>
            <begin position="24"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="13">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="666"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="666"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="690"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC44489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="724" mass="79367" checksum="7910496DEA07A262" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZB30</accession>
    <name>W6ZB30_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">COCMIDRAFT_91296</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="KI963958">
        <property type="protein sequence ID" value="EUC47028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686525.1">
        <property type="nucleotide sequence ID" value="XM_007688335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZB30"/>
    <dbReference type="STRING" id="930090.W6ZB30"/>
    <dbReference type="GeneID" id="19127857"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_91296"/>
    <dbReference type="eggNOG" id="KOG2698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049768_1_0_1"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.10:FF:000003">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000012">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="13">
        <location>
            <begin position="148"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="72"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EUC47028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="326" mass="36410" checksum="1547896C295E3D06" modified="2014-04-16" version="1">MDADTTKPHSAVPTHMVNGGSPLRLTTEARDKKERENLFNAIETSNRGRQVVNFDGPTGYFPAKAFVANNNGGSANSGLEMSNGHTEQESEGEDAVVQTPLATSRAHSPYTQHPTIDFDGLSWPSKGTRHRKEATDEEKAENLKKLSGAVRTMLECLGEDPDREGLLDTPERYAKALLFFTKGYEENLRDIVNGAVFHEDHDELVIVRDIEIFSLCEHHLVPFTGKMHIGYIPNRRVIGLSKLARIAEMFARRFQVQERLTKQVALALSEMLQPQGVAVVVESSHLCMVMRGVQKTGATTTTSCMLGCMRSREKTRQEFLNLINRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZBL0</accession>
    <name>W6ZBL0_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_90932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
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        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="737"/>
            <end position="962"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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        <location>
            <begin position="117"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="565"/>
            <end position="614"/>
        </location>
    </feature>
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        <location>
            <begin position="633"/>
            <end position="659"/>
        </location>
    </feature>
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        <location>
            <begin position="1043"/>
            <end position="1074"/>
        </location>
    </feature>
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        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
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        <location>
            <begin position="265"/>
            <end position="281"/>
        </location>
    </feature>
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        <location>
            <begin position="282"/>
            <end position="294"/>
        </location>
    </feature>
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        <location>
            <begin position="304"/>
            <end position="316"/>
        </location>
    </feature>
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        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
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        <location>
            <begin position="396"/>
            <end position="413"/>
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        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
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        <location>
            <begin position="581"/>
            <end position="599"/>
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    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EUC47173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="1092" mass="122365" checksum="10BD69C1F96CB551" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZDB5</accession>
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        <recommendedName>
            <fullName evidence="7">NIMA interactive protein</fullName>
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    </protein>
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        <name evidence="5" type="ORF">COCMIDRAFT_89253</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ADIP family.</text>
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    </dbReference>
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        <property type="entry name" value="Afadin/alpha-actinin-bd"/>
    </dbReference>
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        <property type="entry name" value="AFADIN/ALPHA-ACTININ-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47057:SF1">
        <property type="entry name" value="AFADIN_ALPHA-ACTININ-BINDING PROTEIN"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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        </location>
    </feature>
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        </source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="619" mass="69025" checksum="27D36E6F17B24EE7" modified="2014-04-16" version="1"> </sequence>
</entry>
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        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">COCMIDRAFT_3095</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="809632at2759"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
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    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
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    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF19">
        <property type="entry name" value="ENOYL REDUCTASE (ER) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="23"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC47963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="353" mass="37636" checksum="48FBD550BA0EC917" modified="2014-04-16" version="1">MSGQETRQWVLANPPEGEPIISGENATFKLQTTTLPPPGPDEVLLKTLYFSNDPAQRAWIITNIEPERLYLPPVQKGEAMRSGAICEVVTSNSTSLKPGQLVLDFLLSWSEYLVVPANTVRPIHPDPSAGTRATHFVGALGATGLTAYYGLVDVARATAADTVVVSGAAGATGSLVVQIAKHIIGCKRVIGIAGGAQKCKWVESLGADACVDYQSASFKQDLRAATEGYVDVYFDNVGGEILSLMLTRMKKFGRVAACGAVSTYNSGDGGVMNWVDVISNRIEVKGFILLDAMEQGKTGAMIEELVKAAKEGKIQLGPETETVVPTKFEDVPKTWVMLFNGGNTGKLITELKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZE69</accession>
    <name>W6ZE69_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase C45 hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_88156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963944">
        <property type="protein sequence ID" value="EUC48163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685359.1">
        <property type="nucleotide sequence ID" value="XM_007687169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZE69"/>
    <dbReference type="STRING" id="930090.W6ZE69"/>
    <dbReference type="GeneID" id="19127212"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88156"/>
    <dbReference type="eggNOG" id="ENOG502RY9N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037787_1_0_1"/>
    <dbReference type="OrthoDB" id="189997at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.60.10">
        <property type="entry name" value="Penicillin V Acylase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047794">
        <property type="entry name" value="C45_proenzyme-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047801">
        <property type="entry name" value="Peptidase_C45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005079">
        <property type="entry name" value="Peptidase_C45_hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040521">
        <property type="entry name" value="C45_proenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34180:SF1">
        <property type="entry name" value="BETA-ALANYL-DOPAMINE_CARCININE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34180">
        <property type="entry name" value="PEPTIDASE C45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03417">
        <property type="entry name" value="AAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C45 hydrolase" evidence="1">
        <location>
            <begin position="106"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="341" mass="37816" checksum="AD6EAECECC4BD149" modified="2014-04-16" version="1">MLFVECEGTPYQIGYQHGQAAKLQINRSIEFYACLFLKNCKQRWPQVLEHALAFEQRAKEQWPMFHQEMQGIADGSGRDVLDIVALNVRTEINFGLFSDGCTALSWHTSDHAWLAQNWDWMTEQKQNLIITKIAQPNKPTIIQVTEAGILGKIGFNSSGVGTLFNAIKVYGVNSTRMPAHFGLRMALESKSADEAVRALQSFGMASSAHILIADATTAVGLEFTKSTFARLSPDSTGKIIHTNHLLLEHPGETDTVWLKDSLTRLQTMTENAKALGDGAGWEQVGQLFEDEQNAPGSICRTETKETGSGTLFNIVMDLKSKKAAVRIGRPIEVEETINLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFG8</accession>
    <name>W6ZFG8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proline--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_81720</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="2"/>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682905.1">
        <property type="nucleotide sequence ID" value="XM_007684715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZFG8"/>
    <dbReference type="STRING" id="930090.W6ZFG8"/>
    <dbReference type="GeneID" id="19125925"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_81720"/>
    <dbReference type="eggNOG" id="KOG4163">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_4_1_1"/>
    <dbReference type="OrthoDB" id="1350766at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00862">
        <property type="entry name" value="ProRS_anticodon_zinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.110.30:FF:000001">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000007">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000005">
        <property type="entry name" value="bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF2">
        <property type="entry name" value="BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="88"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC50597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="562" mass="63045" checksum="C14A315429FB3A9D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZFP7</accession>
    <name>W6ZFP7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_86606</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963938">
        <property type="protein sequence ID" value="EUC48703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684740.1">
        <property type="nucleotide sequence ID" value="XM_007686550.1"/>
    </dbReference>
    <dbReference type="STRING" id="930090.W6ZFP7"/>
    <dbReference type="GeneID" id="19126893"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_86606"/>
    <dbReference type="eggNOG" id="KOG0245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001485_20_1_1"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047496">
        <property type="term" value="P:vesicle transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22705">
        <property type="entry name" value="FHA_KIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01365">
        <property type="entry name" value="KISc_KIF1A_KIF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01233">
        <property type="entry name" value="PH_KIFIA_KIFIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000021">
        <property type="entry name" value="Kinesin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000047">
        <property type="entry name" value="Kinesin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022164">
        <property type="entry name" value="Kinesin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022140">
        <property type="entry name" value="Kinesin-like_KIF1-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032405">
        <property type="entry name" value="Kinesin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049780">
        <property type="entry name" value="PH_KIFIA_KIFIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12473">
        <property type="entry name" value="DUF3694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12423">
        <property type="entry name" value="KIF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16183">
        <property type="entry name" value="Kinesin_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="51"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="13">
        <location>
            <begin position="1541"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="645"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1507"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="465"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="790"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="645"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="141"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC48703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1666" mass="186284" checksum="37728FC717B87C24" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZG30</accession>
    <name>W6ZG30_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_92930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963966">
        <property type="protein sequence ID" value="EUC46469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687070.1">
        <property type="nucleotide sequence ID" value="XM_007688880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZG30"/>
    <dbReference type="GeneID" id="19128173"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_92930"/>
    <dbReference type="HOGENOM" id="CLU_2687663_0_0_1"/>
    <dbReference type="OrthoDB" id="3688287at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC46469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="75" mass="8152" checksum="C6DBA065A08B0731" modified="2014-04-16" version="1">MHGRCNTVRRRAGAERWTRPKGEGLERIGAGRGRGTVVGCVHGCARQRQTSYDTGGGRGGGDAMTCAREWHGWHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHK4</accession>
    <name>W6ZHK4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bicarbonate transporter-like transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_1865</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anion exchanger (TC 2.A.31) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963932">
        <property type="protein sequence ID" value="EUC49408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684051.1">
        <property type="nucleotide sequence ID" value="XM_007685861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHK4"/>
    <dbReference type="STRING" id="930090.W6ZHK4"/>
    <dbReference type="GeneID" id="19119958"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_1865"/>
    <dbReference type="eggNOG" id="KOG1172">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002289_7_2_1"/>
    <dbReference type="OrthoDB" id="1735926at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005452">
        <property type="term" value="F:solute:inorganic anion antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046713">
        <property type="term" value="P:borate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050801">
        <property type="term" value="P:monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.570:FF:000003">
        <property type="entry name" value="Anion exchange family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.570">
        <property type="entry name" value="Helical hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011531">
        <property type="entry name" value="HCO3_transpt-like_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003020">
        <property type="entry name" value="HCO3_transpt_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453">
        <property type="entry name" value="ANION EXCHANGE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453:SF38">
        <property type="entry name" value="ANION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00955">
        <property type="entry name" value="HCO3_cotransp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="484"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="9">
        <location>
            <begin position="40"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="9">
        <location>
            <begin position="215"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="557"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="581"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC49408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="600" mass="67218" checksum="4921C35F24F5EF6F" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZHY4</accession>
    <name>W6ZHY4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_84223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683903.1">
        <property type="nucleotide sequence ID" value="XM_007685713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZHY4"/>
    <dbReference type="GeneID" id="19126425"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_84223"/>
    <dbReference type="HOGENOM" id="CLU_1396180_0_0_1"/>
    <dbReference type="OrthoDB" id="10333188at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="201" mass="22679" checksum="0252F2E576040877" modified="2014-04-16" version="1">MAVQIGRRPDVWPHVVARTVPVRVEGLSMLVSNSERYLVNKIGATYAALKFASSTTHDSPIYFWAINTAYVAAYLLHQLRVCLKGRKRQRDVIQQRVGLMYPTVASLVIFELQFRSTYICIYRRVLADILDSEATTSINDHIGTPPPLFPLTAGQMAFLEPQAPLFPSPVSKAKKRYLFVSSKYSTSPAELPRKPLIARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZI32</accession>
    <name>W6ZI32_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">COCMIDRAFT_22819</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963930">
        <property type="protein sequence ID" value="EUC49655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683856.1">
        <property type="nucleotide sequence ID" value="XM_007685666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZI32"/>
    <dbReference type="STRING" id="930090.W6ZI32"/>
    <dbReference type="GeneID" id="19120327"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22819"/>
    <dbReference type="eggNOG" id="KOG0769">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_6_2_1"/>
    <dbReference type="OrthoDB" id="18574at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF2">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="39"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="143"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="246"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="433"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="290"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="446"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EUC49655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="52783" checksum="7AA74509172AF275" modified="2014-04-16" version="1">MADNSPDKINFIYNSQLDAFTLYHVSQENNTHNAIGPALPALGHATSGALGSAISKLITYPVDLVVTRLQVQRQLQHGKEHPHYDGVVDAFLKVYEREGGLKAFYSGCVHETFKGVVDSFLFFLAYSYVRQRRLSARASSHNLPALEEIGVGVIAGAFSKLISTPLQQVVTRKQTAAMMNQGSTIDPPPPLSTKDIASEIWREKGIQGFWSGYSASLILTLNPSITMLLHKALLRLVVPRAKRSDPGGRLTFLLAAISKALASTVTYPFSLAKARAQVSAQKPLSGSGETSDREKSDEPIKSKALQARQRTVFSTILRIAQTEGIRALYEGLGAEVLKGFFSHGITMLMKDHIHSIIISLYFTLQKALRKYPGPEEIAKSASEGVQDIYIHSKDKGIEAAENVTKSAKDIVEKGKEQVASVYSKGAEVAEAASRTAQDALESGSQHAEDVAKTVRDGVDDASQRAVDGITDSRVKDIDGTDKDMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIC8</accession>
    <name>W6ZIC8_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Microbial-type PARG catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_22728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963929">
        <property type="protein sequence ID" value="EUC49755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683750.1">
        <property type="nucleotide sequence ID" value="XM_007685560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIC8"/>
    <dbReference type="STRING" id="930090.W6ZIC8"/>
    <dbReference type="GeneID" id="19120315"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_22728"/>
    <dbReference type="eggNOG" id="ENOG502RY8X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024412_0_1_1"/>
    <dbReference type="OrthoDB" id="9985428at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02452">
        <property type="entry name" value="TIGR02452 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596">
        <property type="entry name" value="DUF2263 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596:SF1">
        <property type="entry name" value="MICROBIAL-TYPE PARG CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="PARG_cat_microb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Microbial-type PARG catalytic" evidence="2">
        <location>
            <begin position="106"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="333" mass="36394" checksum="D2C9BEC76894B408" modified="2014-04-16" version="1">MEQQSILSFLTKSRAPERSPRPQNSRSGHPYQDNSNSESHKKHHSKDKKHHKSKHRGPNHRRNMDLAKVADETKAVLPDILADIPNFDATKSSLTKLDDTDALSPADCPSFKSKASIKVLDMDSFDAALHLDPTYTVQKHLTSSPPTPQAPASTSILVLNLASERSPGGGWQKGALAQEECLCYRSSLSLSLPRSFYPLPTLSAIYTPNVVLFRDSMANGHALFPIAQLQDAASLPAVSVVSAAALRKPALSDDKATFKHLGARAVTKRKIRLVLRIAARNGHSRLVLGALGCGVFANPAEDVAKCFAEVFDEAEFQGGWWEEVVFAVLDNIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIR4</accession>
    <name>W6ZIR4_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_90539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963954">
        <property type="protein sequence ID" value="EUC47294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686181.1">
        <property type="nucleotide sequence ID" value="XM_007687991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIR4"/>
    <dbReference type="GeneID" id="19127709"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_90539"/>
    <dbReference type="eggNOG" id="ENOG502RPIA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110305_0_0_1"/>
    <dbReference type="OrthoDB" id="3672963at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC47294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="220" mass="24981" checksum="5B18788C40D69F91" modified="2014-04-16" version="1">MTRNHAKLGLETPPLSPTVAKEITLRGHLQEVLDKLPQDLPTYHHEELLGKHQQHTSCIYLTLALDGLCFLLHSPLFYYAVSPRIRREEQKARSSETNAATTQTPIVKNAHEGVIREPATYLALSKLCIDIKQEENGWVTRLLYNNAILIEGRDLCKEEDSSFITSFRFFCEEVEFLSSEFRSRERAGAILRGAVSEQDPFGEEETAYSQAEGKSQNTAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZIR6</accession>
    <name>W6ZIR6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_83255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963927">
        <property type="protein sequence ID" value="EUC49880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683537.1">
        <property type="nucleotide sequence ID" value="XM_007685347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZIR6"/>
    <dbReference type="STRING" id="930090.W6ZIR6"/>
    <dbReference type="GeneID" id="19126218"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83255"/>
    <dbReference type="eggNOG" id="ENOG502S2T0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_852550_0_0_1"/>
    <dbReference type="OrthoDB" id="3693598at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058925">
        <property type="entry name" value="zf-C2H2_AcuF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF7">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26082">
        <property type="entry name" value="zf-C2H2_AcuF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC49880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="326" mass="36905" checksum="8165BBFD73231861" modified="2014-04-16" version="1">MTLSVSAQCRSCIAILQEVISASPQPDRNGKNSRNLRMREELDRLSLFVGNIGALHQPESPMSIESRLQGAHDVLTHIVGLLDDLKEVTGELLDIVSGKREGMVSVAEETDDECGGEINHREKLAGPLNYHEHPGGLAYKPQIPNIKQSLRSKPTLDRESLPSFFTKATTIAAERLAPQLNAADESDSDDACSYTTISGSIDGDHESSTNVRIPKLDSLRTGHGKEFECPFCFRIKKFKSERMWKKHVFSDLRPYVCTFPDCDAPYFGDINKWFQHEMMFHRVNYKCFLCAKVFNQEGKYISHLGREHEEVLYYYSIIVLYQPLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJK9</accession>
    <name>W6ZJK9_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MutL C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">COCMIDRAFT_38302</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964019">
        <property type="protein sequence ID" value="EUC43786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689688.1">
        <property type="nucleotide sequence ID" value="XM_007691498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJK9"/>
    <dbReference type="STRING" id="930090.W6ZJK9"/>
    <dbReference type="GeneID" id="19123441"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_38302"/>
    <dbReference type="eggNOG" id="KOG1977">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1978">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005415_0_0_1"/>
    <dbReference type="OrthoDB" id="429932at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF47">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="3">
        <location>
            <begin position="698"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="407"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EUC43786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="982" mass="108158" checksum="0A7CD1E10FAAE175" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZJX1</accession>
    <name>W6ZJX1_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">COCMIDRAFT_82296</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963924">
        <property type="protein sequence ID" value="EUC50323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683211.1">
        <property type="nucleotide sequence ID" value="XM_007685021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZJX1"/>
    <dbReference type="STRING" id="930090.W6ZJX1"/>
    <dbReference type="GeneID" id="19126025"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_82296"/>
    <dbReference type="eggNOG" id="KOG4323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025079_0_0_1"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045814">
        <property type="term" value="P:negative regulation of gene expression, epigenetic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15502">
        <property type="entry name" value="PHD_Phf1p_Phf2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12628:SF10">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12628">
        <property type="entry name" value="POLYCOMB-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="229"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="100"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="340"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="381"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EUC50323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="496" mass="52416" checksum="53EE2F663DCFE8C3" modified="2014-04-16" version="1">MNPPNGPTDQSVADNAGGDGATSTSAVTPQSTTPMAMPPACSSQMASSPPGATAGTTSGPSFPQYSASTAAILERLQGKSGHAAGSAAFEAKRAEILQSYVTSDKLPTPPPAVTTGRRGRGGRVSTPSNLKTEVGASPAPTSSGRASGRGRGRGRGGRGGRGGKRKRSDSDEESHNDDDGDSDVSDSYTPLPTRTKSGRSVNKPVAFVPVIPEPAQGVKRRKSTKTLLAAKCKTCHRETDPSNNRIVFCDACSTAYHQYCHDPPIDNEVVTVLEKEFLCTPCTRAKQTAVEGAHDLVAAEDLSVDQQKRAYFSTLPQHQLVGLLLTATIRHPELPVFPPNVRTLISDTSNTKPQPQEPQQQQEQVQQNQQQPPPPTLQQPSTASPANGATPQFSSHPQSELGSTEAQILGDNSHPRTTIDLAGNQYDEDDGYDTDPPAHYPKAGNGLARTLRPESEDLNWLVDDNFEVFSHGWKGDGTGMGADGTLDGLGEGQKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKA3</accession>
    <name>W6ZKA3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylulose kinase</fullName>
            <ecNumber evidence="7">2.7.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">COCMIDRAFT_88890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17140"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.17" evidence="7"/>
    <dbReference type="EMBL" id="KI963947">
        <property type="protein sequence ID" value="EUC47889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685617.1">
        <property type="nucleotide sequence ID" value="XM_007687427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKA3"/>
    <dbReference type="STRING" id="930090.W6ZKA3"/>
    <dbReference type="GeneID" id="19127370"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_88890"/>
    <dbReference type="eggNOG" id="KOG2531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016149_5_0_1"/>
    <dbReference type="OrthoDB" id="1728974at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004856">
        <property type="term" value="F:D-xylulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005998">
        <property type="term" value="P:xylulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07776">
        <property type="entry name" value="ASKHA_NBD_FGGY_SpXK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000118">
        <property type="entry name" value="Xylulose kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042024">
        <property type="entry name" value="D-XK_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF57">
        <property type="entry name" value="XYLULOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="8">
        <location>
            <begin position="140"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="9">
        <location>
            <begin position="306"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EUC47889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="603" mass="65532" checksum="253DD6B05A7F9F98" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKL6</accession>
    <name>W6ZKL6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">COCMIDRAFT_99048</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the enhancer of polycomb family.</text>
    </comment>
    <dbReference type="EMBL" id="KI964011">
        <property type="protein sequence ID" value="EUC44116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007689380.1">
        <property type="nucleotide sequence ID" value="XM_007691190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKL6"/>
    <dbReference type="STRING" id="930090.W6ZKL6"/>
    <dbReference type="GeneID" id="19129387"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_99048"/>
    <dbReference type="eggNOG" id="KOG2261">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010580_1_0_1"/>
    <dbReference type="OrthoDB" id="435275at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Enhancer of polycomb-like N-terminal" evidence="10">
        <location>
            <begin position="11"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="318"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="419"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="536"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="570"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EUC44116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="587" mass="66979" checksum="87942891F8BDBF3D" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKW5</accession>
    <name>W6ZKW5_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_21948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963922">
        <property type="protein sequence ID" value="EUC50643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682833.1">
        <property type="nucleotide sequence ID" value="XM_007684643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZKW5"/>
    <dbReference type="GeneID" id="19120145"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_21948"/>
    <dbReference type="eggNOG" id="ENOG502S7BG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_685093_0_0_1"/>
    <dbReference type="OrthoDB" id="5286775at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="403" mass="45487" checksum="B11DE9DBABCA2116" modified="2014-04-16" version="1">MAFLRGVSDRIWSYMSPRKTQQRRDKPYAFKKPAVPTRTTDAHQAAAKPVITEESSDAPVKTRDPRSPSPQCDIDATLLPPSPPASAMLSDDLEGDTLLPLSPITPGQRAEGSSLDEWDANEETMVVDDGTYMDQQKNINAEEERRRRDQQGQELRDSGWSEDAVFLFQKLGMRGFEPLLPIGWINDFETLPEDLFTENLDKAFIKPAFGTEYGAQHALNKLFDLGGFVRDAWHTRAKRTPAFQIGKAVKAFTKWAMKDGKVDHLWSQLPLFQTVTFSRHVHPSVGEEKMLEKLGRLHDLWYDALKIGEAEQRGDSVVPEVPTLYGITASHSVMAFVSYAPGNSNRDQPQLRLIAMFDFNKEGYDVWNSLAIAIFIIHCRNRMMQLSECLSGPDTLTEEDPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZKX6</accession>
    <name>W6ZKX6_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dynamin GTPase</fullName>
            <ecNumber evidence="2">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_37873</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="2"/>
    <dbReference type="EMBL" id="KI964008">
        <property type="protein sequence ID" value="EUC44226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZM56</accession>
    <name>W6ZM56_COCMI</name>
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            <fullName evidence="10">Glutamate--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
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        <alternativeName>
            <fullName evidence="9">Glutamyl-tRNA synthetase</fullName>
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        <name evidence="15" type="ORF">COCMIDRAFT_21458</name>
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        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
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    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
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            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
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        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
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        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
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    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="An anticodon-binding domain of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="13">
        <location>
            <begin position="51"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class I anticodon-binding" evidence="14">
        <location>
            <begin position="418"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00072917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC51063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="541" mass="61721" checksum="BBBC29117A410EC5" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMR7</accession>
    <name>W6ZMR7_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="3">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_79324</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="3"/>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682267.1">
        <property type="nucleotide sequence ID" value="XM_007684077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMR7"/>
    <dbReference type="STRING" id="930090.W6ZMR7"/>
    <dbReference type="GeneID" id="19125451"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79324"/>
    <dbReference type="eggNOG" id="ENOG502QQFD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031603_2_0_1"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046355">
        <property type="term" value="P:mannan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000299">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF40">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004887603" description="mannan endo-1,4-beta-mannosidase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="7">
        <location>
            <begin position="34"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC51400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="491" mass="55477" checksum="8AAF1C132EE789AD" modified="2014-04-16" version="1">MKASLQLLLASLAAGSVLPRNEQTSHESAIADDDFVYVEGTRLYNKDGLYYLTGMNYWACMNLAASDSAGGNYSRLVTELDQMAAHGVNHLRIMASSEGAPTPQPFRMSPALQEAPGEYNEEIFQGLDICLAEMSKRGMRATMTLNNQWQWSGGFAQYVSWANNNTKIPYPPSWNLTASPQREVPGTGWGNYTEQGVDAASYNEFIAYANLIYNNTQAEQWYKDHIKTVMNRRNTVTGLLYTEDPAIMTWQLANEPQPSDILGYTGPYSLFSVPNPNDLLFPWVDRISSYIHSISPRQLISVGLESKQGEYYFKRVHDFPTVSYATTHCWVQNWGIYDMYGESDANLATSQQFARDFMKNSSRWALDIGKPVFLEEFGMARDNWVNKNKEYPYLSSVPTTHKDAYFTTIIGTVMDEFRNGGAYVGTCPWAYSGLYRPETQRANEFGMVWAGDPPHESPGWYGLYDDDHAMDIVKAQQEMIAQWIAENGTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZMY2</accession>
    <name>W6ZMY2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_23434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963937">
        <property type="protein sequence ID" value="EUC48869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684610.1">
        <property type="nucleotide sequence ID" value="XM_007686420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZMY2"/>
    <dbReference type="GeneID" id="19120431"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_23434"/>
    <dbReference type="HOGENOM" id="CLU_414457_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC48869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="662" mass="72198" checksum="DA0450F5B30A6BFB" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN05</accession>
    <name>W6ZN05_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">COCMIDRAFT_26816</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963994">
        <property type="protein sequence ID" value="EUC44956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688525.1">
        <property type="nucleotide sequence ID" value="XM_007690335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN05"/>
    <dbReference type="GeneID" id="19121007"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26816"/>
    <dbReference type="eggNOG" id="ENOG502S18D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027438_1_1_1"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="522"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EUC44956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="619" mass="69508" checksum="43ADAFC178C5B84C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZN45</accession>
    <name>W6ZN45_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aminopeptidase</fullName>
            <ecNumber evidence="11">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">COCMIDRAFT_33600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9 11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="11"/>
    <dbReference type="EMBL" id="KI963936">
        <property type="protein sequence ID" value="EUC48919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684513.1">
        <property type="nucleotide sequence ID" value="XM_007686323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZN45"/>
    <dbReference type="STRING" id="930090.W6ZN45"/>
    <dbReference type="MEROPS" id="M01.A25"/>
    <dbReference type="GeneID" id="19122360"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33600"/>
    <dbReference type="eggNOG" id="KOG1046">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003705_0_1_1"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1910:FF:000004">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF171">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="14">
        <location>
            <begin position="13"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="12">
        <location>
            <begin position="251"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="13">
        <location>
            <begin position="545"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EUC48919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="885" mass="99505" checksum="1409C4AD3693A45C" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZNP4</accession>
    <name>W6ZNP4_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Scytalone dehydratase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_37042</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the scytalone dehydratase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963989">
        <property type="protein sequence ID" value="EUC45166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007688290.1">
        <property type="nucleotide sequence ID" value="XM_007690100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZNP4"/>
    <dbReference type="STRING" id="930090.W6ZNP4"/>
    <dbReference type="GeneID" id="19123169"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_37042"/>
    <dbReference type="eggNOG" id="ENOG502S0P5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101889_0_0_1"/>
    <dbReference type="OrthoDB" id="5281072at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030411">
        <property type="term" value="F:scytalone dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006582">
        <property type="term" value="P:melanin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00531">
        <property type="entry name" value="NTF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004235">
        <property type="entry name" value="Scytalone_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049884">
        <property type="entry name" value="Scytalone_dh"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02982">
        <property type="entry name" value="Scytalone_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF024851">
        <property type="entry name" value="SCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Scytalone dehydratase-like" evidence="6">
        <location>
            <begin position="13"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR024851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR024851-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR024851-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC45166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="162" mass="18793" checksum="290AD2E4169CD055" modified="2014-04-16" version="1">MPHKTEVRPAPADIIECQAAAYEWAESYDSKDWDRLSRCLAPELYIDYRTVMGMMWEKMPAAEFLGMASSPRFLGNARIKTQHFMGQTKWIQKEPGYIIGHHQMRVAHQKYEDDALTQVLYKGHAHGNATLHYRQVDGEWKFAGLEPGIRWSEGDYGKIFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZPM2</accession>
    <name>W6ZPM2_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">COCMIDRAFT_26297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963982">
        <property type="protein sequence ID" value="EUC45561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687924.1">
        <property type="nucleotide sequence ID" value="XM_007689734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZPM2"/>
    <dbReference type="GeneID" id="19120907"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_26297"/>
    <dbReference type="HOGENOM" id="CLU_1250465_0_0_1"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EUC45561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="221" mass="23765" checksum="A657DD3685A3A105" modified="2014-04-16" version="1">MAVSREVLHVHYTWIVEQGRREGQGRSDLEVPSGSLPPAASGGLSWVSWATVGTGLESGTVGPANDACATTSLHTSQPVLRPAAPLGPSSVPRVAVLPPSRDYSRFPSARQVLVAASICFWHVSRRRHSARPTAISHFQLYRGAWRSSRRPHVDPSSSCVCVLLVPSLKLAWMLHGAVAAPHPDVEKGTSSKRAFSHHVSTSGPDLLRVRGSMYPDLFASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQI3</accession>
    <name>W6ZQI3_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_25939</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KI963974">
        <property type="protein sequence ID" value="EUC45961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007687507.1">
        <property type="nucleotide sequence ID" value="XM_007689317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQI3"/>
    <dbReference type="GeneID" id="19120853"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_25939"/>
    <dbReference type="eggNOG" id="ENOG502STHM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021978_0_0_1"/>
    <dbReference type="OrthoDB" id="3266505at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="76"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="645"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="645"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC45961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="683" mass="75786" checksum="E9DC43634AAAB0BD" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZQT8</accession>
    <name>W6ZQT8_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_83695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963928">
        <property type="protein sequence ID" value="EUC49859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683701.1">
        <property type="nucleotide sequence ID" value="XM_007685511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZQT8"/>
    <dbReference type="GeneID" id="19126308"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_83695"/>
    <dbReference type="eggNOG" id="ENOG502TD2T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061590_0_0_1"/>
    <dbReference type="OrthoDB" id="3797508at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC49859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="288" mass="31761" checksum="184145D11CDF24BF" modified="2014-04-16" version="1">MCWVTLTPSRGKKKGYQSTSDSSCVEDIVRVHRNPASPRLTNVRIKAPSVDVEVDEKLTHAHAYPHLQHHHRHPHLHPLHMHPIHGEHHLGVSLGLGHQHYRGSLDMSETWDPKLRGHGRKRSIPSPCPPPPPSTCPPPEPEPAPAPSHPPPPSCSPSSSPPPSTSPADTSPLIPPTIPRDPIYHTQIIQPTSPRTRNPGPSTVRETTRIALRTSTSNQPQQQQRHPRNNLRRVAGYQVLGRQVPWDWDCISSTAGSSNAGAKGKWVRRKSGGAGLVYPPFGDAEKWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZRA9</accession>
    <name>W6ZRA9_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_32610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">ATCC 44560</strain>
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    </dbReference>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Bushley K.E."/>
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                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
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                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
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                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
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                <person name="LaButti K."/>
                <person name="Han J."/>
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        </source>
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    </evidence>
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        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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            </authorList>
            <dbReference type="PubMed" id="23357949"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
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                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
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        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Glu-tRNAGln amidotransferase C subunit"/>
        <property type="match status" value="1"/>
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    <feature type="domain" description="Glutamyl-tRNA amidotransferase complex subunit Gta3" evidence="1">
        <location>
            <begin position="77"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EUC50454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="206" mass="23275" checksum="72AF342D9796E59A" modified="2014-04-16" version="1">MASRRVFAAVKLYRPTPCLQIRSFAPSTLRLEKDSKESAHPRKNVGIHPSELEQLLAEPTWSVESLLPPKTRVPDAPQVTSQQLHHLLRLSALPPPETPEQEKKMLDTLAAQLHFVGKIQEVDTTGVMPLRAIRDETAAAEEEQKITLETLKDALAKEKVVGRHHKRIQRDNTPVDAKDVEDWDVLGSAERKSSKYFVVESERPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZSJ6</accession>
    <name>W6ZSJ6_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_32304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963923">
        <property type="protein sequence ID" value="EUC50484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007683035.1">
        <property type="nucleotide sequence ID" value="XM_007684845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZSJ6"/>
    <dbReference type="GeneID" id="19122069"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_32304"/>
    <dbReference type="eggNOG" id="ENOG502SVX1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_644266_0_0_1"/>
    <dbReference type="OrthoDB" id="5421765at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC50484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="469" mass="50112" checksum="5041E49C1F06D12D" modified="2014-04-16" version="1">MARPLRVRSFDNVLGPHPQGRDAAPLECDGQNDIPECYSGTAGGVASKPDTPGVFPRTTDDSALAVETNGFGGSKPTVVQTSDIITATMIPTQSVNPTLSTTVVSSEPSLVTAGSVEGPTHDNSGLSTGEVVGIAVGTLFIGAALAFLAAFFVFKRRNRRQNANTGDRGYPSYGDSVPELTMVQKSVGSLGDMHSPYVQVPQTPMLARRPIPPAIPAPVNMDTTTNTDIAGFLPPIARDSEVGDRVSALFEKMHEHIERNYRDVHASITPSMESGIASFGAKGVNMTEMLQECSNPTTALKHALVSYVMAITSWNKDEEHAGTLFPEELSNMKSERHSNSSDPGATAAASLLKRISVYLYTSTSGTPESAQSWTIQSSAREAAEHFSMTFFPWANPTSSDQQKDEDLTSIIIEALEISIWLFGQPEVYEFEWGGAGRRGVLVSPGLVRRTNATGDEQGTRVVEGAVVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUG5</accession>
    <name>W6ZUG5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">COCMIDRAFT_24709</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963953">
        <property type="protein sequence ID" value="EUC47386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007686070.1">
        <property type="nucleotide sequence ID" value="XM_007687880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUG5"/>
    <dbReference type="GeneID" id="19120627"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_24709"/>
    <dbReference type="eggNOG" id="ENOG502S073">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024655_2_0_1"/>
    <dbReference type="OrthoDB" id="5355161at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF3">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EUC47386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="422" mass="47689" checksum="493ABBD77E15C0ED" modified="2014-04-16" version="1">MPADRTRGTNSQGRQRSCSECAKSKRKCGLEQPSCARCIRQRFSCIYPSQPHINATVPYSFTTDIDPTINQLNLPLDLTDLENINLDFNFDESAIVTTSNTDTLDFDFPANTTCITPFPAALQNSPHLENKIAIQKALTQARNYCLSINLSPYARARMGYFLEHMQLVPKIMVEQNCTPWMHPTLYDKNMPRCMQDAHATCALYITKNEINAERVTYHIRSRVEELIKETVPETPIEILARTQAIMLYQLMLVFGGDIHFRTQADALSSQLDDMGAMLLPIATEENEHVGALPLYPSTAAHSAWRSFVFRESARRTVLAAYQFTVMYTVLTGQIKTCSQDVALQSHITLSAHLWRATNAFDFAMSWNAKNHFVVKGLDFTNLLKEAQPDDLDVFGNILLISLQGIDDIRGWYHIRGGTLELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZUU5</accession>
    <name>W6ZUU5_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-CoA synthetase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">COCMIDRAFT_79622</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963918">
        <property type="protein sequence ID" value="EUC51349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007682238.1">
        <property type="nucleotide sequence ID" value="XM_007684048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZUU5"/>
    <dbReference type="STRING" id="930090.W6ZUU5"/>
    <dbReference type="GeneID" id="19125513"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_79622"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_2_1"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000026">
        <property type="entry name" value="Short-chain-fatty-acid--CoA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF422">
        <property type="entry name" value="BCDNA.GH02901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="48"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="455"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EUC51349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="560" mass="61956" checksum="C0D51241AB978FFE" modified="2014-04-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX31</accession>
    <name>W6ZX31_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_87475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685045.1">
        <property type="nucleotide sequence ID" value="XM_007686855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX31"/>
    <dbReference type="STRING" id="930090.W6ZX31"/>
    <dbReference type="GeneID" id="19127071"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87475"/>
    <dbReference type="eggNOG" id="KOG3504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169255_2_0_1"/>
    <dbReference type="OrthoDB" id="996720at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002673">
        <property type="entry name" value="Ribosomal_eL29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01779">
        <property type="entry name" value="Ribosomal_L29e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="81" mass="9273" checksum="10148AB8B175EF71" modified="2014-04-16" version="1" fragment="single">ALRQYHTAKSTSTTVAMAKSKNSSQHNQSKKNHRNGIKKPKTHRYPSLKGTDPKFRRNHRHALHGTMRALKEVKEGKRESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZX92</accession>
    <name>W6ZX92_COCMI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">COCMIDRAFT_87333</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">ATCC 44560</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. AKT2 hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="KI963941">
        <property type="protein sequence ID" value="EUC48466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007685087.1">
        <property type="nucleotide sequence ID" value="XM_007686897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZX92"/>
    <dbReference type="STRING" id="930090.W6ZX92"/>
    <dbReference type="GeneID" id="19127036"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_87333"/>
    <dbReference type="eggNOG" id="KOG4178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_3_1"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046464">
        <property type="term" value="P:acylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="36"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EUC48466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000054032"/>
        </source>
    </evidence>
    <sequence length="298" mass="33393" checksum="F2743B7FD7CEB04C" modified="2014-04-16" version="1">MPPEHSSGRTYILHPNGQKSHYILNDFTDPWKPHETVLIQHGFGRHSAFWYHWIPALSRHYRVVRRDLRGHGYSSYPGQKQTAEGDGDYEYNVDTIIGEIIDTLDQLGLQKVHFLGESTSGMLGEILAARHPERLLSLTVCSSPTYLPPAALQMFAFGHKDWPTACRQLGTRGWTEALAQVPGTIPISDSVYLPWYLGQVEVSDGEGLAQYAEFLSKLDARPWLDKIKVPTLILSPTQSAAVKAQDMEALRDTIPGSQLVPIFKPGHEIYVTAAEECQQAFLAFLEGLKKRDDTTQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-04-16" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>W6ZXB1</accession>
    <name>W6ZXB1_COCMI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">COCMIDRAFT_33976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Bipolaris oryzae ATCC 44560</name>
        <dbReference type="NCBI Taxonomy" id="930090"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Dothideomycetes</taxon>
            <taxon>Pleosporomycetidae</taxon>
            <taxon>Pleosporales</taxon>
            <taxon>Pleosporineae</taxon>
            <taxon>Pleosporaceae</taxon>
            <taxon>Bipolaris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2013" name="PLoS Genet." volume="9" first="E1003233" last="E1003233">
            <title>Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens.</title>
            <authorList>
                <person name="Condon B.J."/>
                <person name="Leng Y."/>
                <person name="Wu D."/>
                <person name="Bushley K.E."/>
                <person name="Ohm R.A."/>
                <person name="Otillar R."/>
                <person name="Martin J."/>
                <person name="Schackwitz W."/>
                <person name="Grimwood J."/>
                <person name="MohdZainudin N."/>
                <person name="Xue C."/>
                <person name="Wang R."/>
                <person name="Manning V.A."/>
                <person name="Dhillon B."/>
                <person name="Tu Z.J."/>
                <person name="Steffenson B.J."/>
                <person name="Salamov A."/>
                <person name="Sun H."/>
                <person name="Lowry S."/>
                <person name="LaButti K."/>
                <person name="Han J."/>
                <person name="Copeland A."/>
                <person name="Lindquist E."/>
                <person name="Barry K."/>
                <person name="Schmutz J."/>
                <person name="Baker S.E."/>
                <person name="Ciuffetti L.M."/>
                <person name="Grigoriev I.V."/>
                <person name="Zhong S."/>
                <person name="Turgeon B.G."/>
            </authorList>
            <dbReference type="PubMed" id="23357949"/>
            <dbReference type="DOI" id="10.1371/journal.pgen.1003233"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">ATCC 44560</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KI963940">
        <property type="protein sequence ID" value="EUC48491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_007684925.1">
        <property type="nucleotide sequence ID" value="XM_007686735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="W6ZXB1"/>
    <dbReference type="STRING" id="930090.W6ZXB1"/>
    <dbReference type="GeneID" id="19122452"/>
    <dbReference type="KEGG" id="bor:COCMIDRAFT_33976"/>
    <dbReference type="eggNOG" id="ENOG502SAXX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043406_0_0_1"/>
    <dbReference type="OrthoDB" id="2402960at2759"/>
    <dbReference type="Proteomes" id="UP000054032">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
   